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Len
Stephens, Karen Anderson, David Stokoe, Hediye Erdjument-Bromage, Gavin F. Painter, Andrew B. Holmes, Piers R.J. Gaffney, Colin B. Reese, Frank McCormick, Paul Tempst, J. Coadwell, Phillip T. Hawkins (1998) Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent
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David Stokoe, Leonard R. Stephens, Terry
Copeland, Piers R. J. Gaffney, Colin B. Reese, Gavin F. Painter, Andrew B. Holmes, Frank McCormick, Phillip T. Hawkins (1997) Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B.
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L. Stephens, A. Smrcka, F.T. Cooke, T.R. Jackson, P.C. Sternweis, P.T. Hawkins (1994) A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits.
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P.T. Hawkins, T.R. Jackson, L.R. Stephens (1992) Platelet-derived growth factor stimulates synthesis of Ptdlns(3,4,5)P3 by activating a Ptdlns(4,5)P2 3-OH kinase.
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122:-activated Type 1B PI3K (PI3KΥ) and, in a sustained body of work, defined its structure, explained its complex pattern of regulation by GβΥ and
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as the key output signal produced by this enzyme. They identified and isolated the
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activation, a key pathway through which PtdIns(3,4,5)P3 formation regulates
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functions in eukaryotic cells. Together with his long-time collaborator
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Phill
Hawkins has contributed much to the understanding of
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16:"Phill Hawkins" redirects here. Not to be confused with
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Phill
Hawkins has received several awards, including:
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is the main substrate of receptor-controlled Type 1
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185:) in 1990 and became a group leader in 2003.
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694:Academics of the University of Cambridge
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724:Alumni of the University of Birmingham
199:Fellow of the Royal Society of London
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181:(UK). He joined the AFRC IAPGR (now
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297:Activation of Protein Kinase B.
82:Phillip (Phill) Thomas Hawkins
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91:, senior group leader at the
729:Fellows of the Royal Society
699:British molecular biologists
673:Prince Andrew, Duke of York
87:(born 5 October 1958) is a
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133:. They - in parallel with
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112:phosphoinositide 3-kinases
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153:Phill Hawkins received a
126:, and proved its role in
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550:Maria Grazia Spillantini
530:Christopher J. Schofield
219:"Dr Phillip Hawkins FRS"
175:University of Birmingham
189:Awards and recognition
106:, he established that
714:British immunologists
510:William D. Richardson
163:University of Bristol
318:Phill Hawkins' group
622:Margaret Buckingham
560:Brigitta Stockinger
128:inflammatory events
89:molecular biologist
60:signal transduction
322:Babraham Institute
183:Babraham Institute
143:cell proliferation
104:Leonard R Stephens
93:Babraham Institute
70:Babraham Institute
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173:(1983) from the
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231:. Retrieved
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171:Biochemistry
159:Biochemistry
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135:Dario Alessi
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66:Institutions
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18:Phil Hawkins
709:1958 births
637:Eric Kandel
606:Bill Bryson
580:Terry Wyatt
545:Terry Speed
525:John Savill
475:Edith Heard
400:Mervyn Bibb
233:25 February
35:Nationality
688:Categories
535:Paul Sharp
520:Kerry Rowe
500:Anne Mills
395:Mike Bevan
390:Keith Ball
205:References
56:immunology
425:Ara Darzi
304:, 710-714
287:, 567-570
254:, 157-159
179:Cambridge
161:from the
627:Chen Zhu
599:Honorary
364:elected
615:Foreign
373:Fellows
366:in 2013
360:of the
358:Fellows
320:at the
299:Science
282:Science
270:, 83-93
131:in vivo
39:British
249:Nature
52:Fields
666:Royal
265:Cell
235:2014
149:Life
120:GPCR
302:279
285:277
252:358
169:in
167:PhD
157:in
155:BSc
124:Ras
85:FRS
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268:77
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