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Although the mechanism is still unclear, it is thought to be caused by right to left shunting of blood flow due to an anatomic defect allowing communication between right and left-sided circulation, such as an
110:, patent foramen ovale, or pulmonary atrioventricular malformations, and a functional component that causes blood to move through the shunt, such as
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189:"Platypnea–Orthodeoxia Syndrome: Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea"
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Henkin, Stanislav; Negrotto, Sara; Pollak, Peter M.; Cullen, Michael W.; O'Cochlain, D. Fearghas; Wright, R. Scott (2015-10-01).
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286:"Cardiac Platypnea-Orthodeoxia Syndrome: An Often Unrecognized Malady: Cardiac Platypnea-Orthodeoxia Syndrome"
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132:"Platypnea-Orthodeoxia Syndrome: Diagnostic Challenge and the Importance of Heightened Clinical Suspicion"
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Knapper, Joseph T.; Schultz, Jason; Das, Gladwin; Sperling, Laurence S. (October 2014).
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255:. If this is an intentional citation to a retracted paper, please replace
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102:, or pulmonary shunting. In some cases, the cause is multifactorial.
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De
Vecchis, Renato; Baldi, Cesare; Ariano, Carmelina (2016-09-23).
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Shortness of breath and low oxygen saturation only while upright
114:, pulmonary hypertension, or absent superior vena cava.
94:), but no symptoms when lying down. It can be caused by
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269:|...|intentional=yes}}
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78:is a condition in which a person has
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96:ventilation-perfusion mismatch
76:Platypnea–orthodeoxia syndrome
25:Platypnea-orthodeoxia syndrome
1:
136:Texas Heart Institute Journal
352:. You can help Knowledge by
193:Journal of Clinical Medicine
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331:
399:Breathing abnormalities
84:low oxygen saturations
65:Differential diagnosis
40:cardiothoracic surgery
261:|...}}
238:(Retracted, see
148:10.14503/THIJ-14-4596
100:intracardiac shunting
69:Intracardiac shunting
108:atrial septal defect
290:Clinical Cardiology
244:10.3390/jcm10040883
80:shortness of breath
206:10.3390/jcm5100085
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302:10.1002/clc.22301
112:Ebstein's Anomaly
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296:(10): 645–649.
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92:orthodeoxia
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199:(10): 85.
118:References
54:hepatology
36:Cardiology
267:retracted
259:retracted
215:2077-0383
156:0730-2347
88:platypnea
50:neurology
31:Specialty
320:24912004
252:33671845
233:27669319
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