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Pneumocystis jirovecii

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originally seen by Chagas have not yet been named as distinct species. Many other undescribed species presumably exist and those that have been detected in many mammals are only known from molecular sample detection from lung tissue or fluids, rather than by direct physical observation. Currently,
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The term PCP, which was widely used by practitioners and patients, has been retained for convenience, with the rationale that it now stands for the more general Pneumocystis pneumonia rather than Pneumocystis carinii pneumonia.
1761:"Pneumocystis oryctolagi sp. nov., an uncultured fungus causing pneumonia in rabbits at weaning: review of current knowledge, and description of a new taxon on genotypic, phylogenetic and phenotypic bases" 450: 254:
are not known, but presumably all resemble the others in the genus. The terminology follows zoological terms, rather than mycological terms, reflecting the initial misdetermination as a
294:-like cysts, eight spores form, which are released through rupture of the cyst wall. The cysts often collapse, forming crescent-shaped bodies visible in stained tissue. Whether 390:
over-replicate and damage alveolar epithelium, causing death by asphyxiation. Fluid leaks into alveoli, producing an exudate seen as honeycomb/cotton candy appearance on
1260:"Nova tripanozomiase humana: Estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., n. sp., ajente etiolojico de nova entidade morbida do homem" 438:
pneumonia in humans in 1952. After DNA analysis showed significant differences in the human variant, the proposal was made again in 1999 and has come into common use.
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James TY, Kauff F, Schoch CL, Matheny PB, Hofstetter V, Cox CJ, et al. (2006). "Reconstructing the early evolution of Fungi using a six-gene phylogeny".
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was redescribed as a human pathogen in 1942 by two Dutch investigators, van der Meer and Brug, who found it in three new cases: a 3-month-old infant with
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Cushion MT, Keely SP, Stringer JR (2004). "Molecular and phenotypic description of Pneumocystis wakefieldiae sp. nov., a new species in rats".
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from humans are based upon older classifications (still used by many, or those still debating the recognition of distinct species in the genus
864:"Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs" 1564:
Hawksworth DL (2007). "Responsibility in naming pathogens: the case of Pneumocystis jiroveci, the causal agent of pneumocystis pneumonia".
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is incorrect for the human variant, but still describes the species found in rats, and that name is typified by an isolate from rats.
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is correct. A change in the ICNafp now recognizes the validity of the 1976 publication, making the 1999 proposal redundant, and cites
1896: 834: 290:(multilobed) and closely associated with host cells. Globular cysts eventually form that have a thicker wall. Within these 2188: 2005: 1192:"De Novo Assembly of the Pneumocystis jirovecii Genome from a Single Bronchoalveolar Lavage Fluid Specimen from a Patient" 395: 445:, since the organism was believed to be a protozoan. After it became clear that it was a fungus, the name was changed to 617: 64: 510:
available from experimental rats, which can be maintained with infections. Genetic material of other species, such as
1073:- (stem augmentation) plus the genitive inflection appropriate to the sex and number of the person(s) honoured (e.g. 2023: 371:, but also patients with an immune system that is severely suppressed for other reasons, for example, following a 2206: 1066: 298:
takes place within the cysts, or what the genetic status is of the various cell types, is not known for certain.
274: 2257: 2088: 597: 334:. The sexual phase takes place in the host's lungs. This phase is presumed to involve formation of a diploid 1841:"Phylogeny of Pneumocystis carinii from 18 Primate Species Confirms Host Specificity and Suggests Coevolution" 2267: 258:
parasite. It is an extracellular fungus. All stages are found in lungs and because they cannot be cultured
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is typified (both lectotypified and epitypified) by samples from human autopsies dating from the 1960s.
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properties, Frenkel was the first to recognize the human pathogen as a distinct species. He named it "
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was applied to the organisms found in both rats and humans, as the parasite was not yet known to be
311: 136: 126: 116: 106: 2252: 315: 620:, Czechoslovakia, showed in a study of lung sections from 16 children that the organism labelled " 552:
in 1909, who discovered it in experimental animals, but confused it with part of the lifecycle of
1706: 1470: 1151: 816: 387: 183: 175: 59: 1053: 954:"A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship" 913:"Pneumocystis colonization is highly prevalent in the autopsied lungs of the general population" 426:" was proposed for the first time, to distinguish the organism found in humans from variants of 2167: 1314:
Delanoë P, Delanoë M (1912). "Sur les rapports des kystes de Carini du poumon des rats avec le
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was a fungal genus. Recent studies show it to be an unusual, in some ways a primitive genus of
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Cushion MT, Keely SP, Stringer JR (2005). "Validation of the name Pneumocystis wakefieldiae".
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has had a broader application to many species. Frenkel and those before him believed that all
624:" was the causative agent of pneumonia in these children. The following year, Czech scientist 583: 554: 383: 323: 272:
stage is thought to be equivalent to the so-called vegetative state of other species (such as
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species cannot be grown in culture, so the availability of the human disease-causing agent,
283: 406:. In HIV patients, most cases occur when the CD4 count is below 200 cells per microliter. 367:
pneumonia is an important disease of immunocompromised humans, particularly patients with
1445:; etiologic agent of interstitial plasma cell pneumonia of premature and young infants". 743:
from rats actually infects humans. In an intermediate classification system, the various
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from humans could not infect experimental animals such as rats, and that the rat form of
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Vanek J, Jírovec O, Lukes J (1953). "Interstitial plasma cell pneumonia in infants".
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cases – a 4-month-old infant and a 21-year-old adult. There being only one described
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has been sequenced from a bronchoalveolar lavage sample. The genome is small, low in
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n. sp. from man: morphology, physiology, and immunology in relation to pathology".
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Richard S, Almeida JM, Cissé OH, Luraschi A, Nielsen O, Pagni M, Hauser PM (2018).
820: 705: 431: 376: 327: 582:. The genus was again discovered in 1912 by Delanoë and Delanoë, this time at the 391: 1817: 286:
branch of the fungal kingdom. The trophozoite stage is single-celled and appears
2193: 2082: 2010: 1063: 567: 399: 269: 2073: 1745: 668:, which is why both names still appear in publications. However, only the name 430:
in other animals. The organism was named thus in honor of Czech parasitologist
1621: 1600: 689: 347: 96: 1931: 350:. The ascospores may be disseminated by airborne transmission to new hosts. 2123: 1093: 681: 255: 76: 1874: 1825: 1786: 1718: 1675: 1630: 1585: 1550: 1466: 1427: 1225: 1147: 1039: 1021: 987: 969: 938: 897: 812: 1891: 1666: 1645: 1458: 1207: 879: 708:
with each species. Currently, only five species have been formally named:
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in Paris, who found it in rats and proposed the genus and species name
2154: 1984: 1710: 697: 649: 637: 605: 601: 403: 339: 331: 295: 260: 660:- see nomenclature above). Controversy existed over the relabeling of 2180: 1997: 767:. This terminology is still used by some researchers. The species of 579: 335: 319: 212: 86: 1902: 1702: 1395:, the cause of interstitial plasmacellular pneumonia in neonates)". 1360:
Vanek J. (1951). "Atypicka (interstitiálni) pneumonie detí vyvolaná
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puvodce t. zv intertitialnich plasmocelularnich pneumonii kojencw (
929: 912: 693: 609: 520: 457:). Both spellings are commonly used, but according to the ICNafp, 343: 291: 1094:"International Code of Nomenclature for algae, fungi, and plants" 744: 704:
that is incapable of cross-infecting other host species and has
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The earliest report of this genus appears to have been that of
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International Code of Nomenclature for algae, fungi, and plants
453:(ICNafp), which requires such names be spelled with double i ( 368: 1599:
Hugot J, Demanche C, Barriel V, Dei-Cas E, Guillot J (2003).
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is used exclusively for the human pathogen, whereas the name
502:, is limited. Hence, investigation of the whole genome of a 469:
as examples of the change in ICN Article 45, Ex 7. The name
1601:"Phylogenetic systematics and evolution of primate-derived 1605:
based on mitochondrial or nuclear DNA sequence comparison"
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Redhead SA, Cushion MT, Frenkel JK, Stringer JR (2006). "
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content, and lacks most amino-acid biosynthesis enzymes.
326:. The mode of sexual reproduction appears to be primary 1364:(Atypical interstitial pneumonia of infants produced by 1169: 952:
Stringer JR, Beard CB, Miller RF, Wakefield AE (2002).
684:, but soon afterwards evidence began accumulating that 382:
Identified by methenamine silver stain of lung tissue,
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If the personal name ends with a consonant (except -
700:, including humans, appears to have its own type of 2057: 1915: 911:Ponce CA, Gallo M, Bustamante R, Vargas SL (2010). 759:, while the original rat infecting form was called 751:or forms. For example, the human "form" was called 1644:Keely S, Fischer J, Cushion M, Stringer J (2004). 346:containing the products of meiosis, eight haploid 250:The complete lifecycles of any of the species of 1337:van der Meer MG, Brug SL (1942). "Infection à 1291:Carini A. (1910). "Formas des eschizogonia do 1241:Vorläufige Mitteilung. Arch. Schiff. Tropenhyg 1113: 1111: 1109: 1107: 616:. Nine years later (1951), Dr. Josef Vanek at 1804:species, co-evolution and pathogenic power". 443:International Code of Zoological Nomenclature 8: 1190:Cisse, O. H; Pagni, M; Hauser, P. M (2012). 786: 784: 1650:sp. nov., a new species in laboratory mice" 648:differed physiologically and had different 612:, they considered the human parasite to be 1903: 1800:Aliouat-Denis, C-M.; et al. (2008). " 42: 31: 1864: 1776: 1665: 1620: 1540: 1320:Comptes Rendus de l'Académie des Sciences 1275: 1215: 1029: 1001:Stringer JR, Beard CB, Miller RF (2009). 977: 928: 887: 857: 855: 780: 1239:Chagas C (1909). "Neue Trypanosomen". 747:in different mammals have been called 731:Historical and even recent reports of 441:The name was spelled according to the 570:infecting humans. The rediscovery of 7: 2217:b50139eb-b8ea-4472-8424-14972a53fd6f 2034:75b8c351-efd0-4789-b7f2-68568114deba 1525:: has the name really been changed?" 739:) which does not mean that the true 1341:chez l'homme et chez les animaux". 1126:: nomenclature and typifications". 514:, can be compared to the genome of 318:phases. Asexual multiplication of 562:) and later called both organisms 25: 1806:Infection, Genetics and Evolution 640:. Following the realization that 1890: 1839:Demanche C, et al. (2001). 1778:10.1111/j.1574-6976.2006.00037.x 1646:"Phylogenetic identification of 1140:10.1111/j.1550-7408.2005.00072.x 1003:"Spelling Pneumocystis jiroveci" 63: 1857:10.1128/JCM.39.6.2126-2133.2001 1759:Dei-Cas E, et al. (2006). 1277:10.1590/S0074-02761909000200008 716:as originally named from rats, 264:, direct observation of living 422:-specific. In 1976, the name " 1: 1578:10.1016/S1473-3099(06)70663-6 1170:"Pneumocystis Genome Project" 837:. Dpd.cdc.gov. Archived from 835:"see DPDx life-cycle diagram" 396:trimethoprim/sulfamethoxazole 392:hematoxylin and eosin-stained 1818:10.1016/j.meegid.2008.05.001 1010:Emerging Infectious Diseases 958:Emerging Infectious Diseases 618:Charles University in Prague 342:, and then production of an 219:. The causative organism of 1054:"ICBN Recommendation 60C.1" 506:is largely based upon true 310:is thought to include both 2284: 2263:Fungal pathogens of humans 1746:10.3852/mycologia.97.1.268 394:slides. Drug of choice is 357: 1622:10.1080/10635150390250893 275:Schizosaccharomyces pombe 189: 182: 165: 158: 60:Scientific classification 58: 50: 41: 34: 692:, related to a group of 598:congenital heart disease 1494:Natl Cancer Inst Monogr 1343:Amer Soc Belge Méd Trop 772:they are cryptic taxa. 322:cells likely occurs by 232:immunocompromised hosts 1917:Pneumocystis jirovecii 1897:Pneumocystis jirovecii 1397:CSL. Hyg. Epid. Mikrob 1069:are formed by adding - 1022:10.3201/eid1503.081060 970:10.3201/eid0809.020096 634:interstitial pneumonia 574:cysts was reported by 529: 447:Pneumocystis jirovecii 373:bone marrow transplant 360:Pneumocystis pneumonia 204:Pneumocystis jirovecii 169:Pneumocystis jirovecii 36:Pneumocystis jirovecii 1667:10.1099/mic.0.26921-0 1490:Pneumocystis jiroveci 1459:10.1542/peds.19.4.543 1441:Gajdusek DC (1957). " 1297:Soc Med Cir São Paulo 1264:Mem Inst Oswaldo Cruz 1208:10.1128/mBio.00428-12 880:10.1128/mBio.02201-17 654:Pneumocystis jiroveci 524: 424:Pneumocystis jiroveci 358:Further information: 230:, particularly among 226:, it is an important 2089:Pneumocystis carinii 2059:Pneumocystis carinii 1899:at Wikimedia Commons 1523:Pneumocystis carinii 1519:Gigliotti F (2005). 1488:Frenkel JK (1976). " 1443:Pneumocystis carinii 1393:Pneumocystis carinii 1389:Pneumocystis carinii 1387:Jírovec O. (1952). " 1366:Pneumocystis carinii 1362:Pneumocystis carinii 1128:J Eukaryot Microbiol 761:Pneumocystis carinii 753:Pneumocystis carinii 724:also from rats, and 588:Pneumocystis carinii 564:Schizotrypanum cruzi 525:Microscopy image of 416:Pneumocystis carinii 193:Pneumocystis carinii 107:Pneumocystidomycetes 18:Pneumocystis carinii 1765:FEMS Microbiol. Rev 1648:Pneumocystis murina 1416:Annales Paediatrici 805:10.1038/nature05110 449:, according to the 414:At first, the name 388:type II pneumocytes 1845:J. Clin. Microbiol 1566:Lancet Infect. Dis 1453:(4 Pt 1): 543–65. 1316:Trypanosoma lewisi 1293:Trypanosoma lewisi 1098:www.iapt-taxon.org 632:" as the cause of 600:and in two of 104 530: 384:type I pneumocytes 332:self-fertilization 268:is difficult. The 211:) is a yeast-like 2240: 2239: 2225:Open Tree of Life 2042:Open Tree of Life 1909:Taxon identifiers 1895:Media related to 1660:(Pt 5): 1153–65. 1258:Chagas C (1909). 1124:Trypanosoma cruzi 799:(7113): 818–822. 584:Pasteur Institute 578:in 1910, also in 558:(causal agent of 555:Trypanosoma cruzi 354:Medical relevance 306:The lifecycle of 200: 199: 151:P. jirovecii 127:Pneumocystidaceae 27:Species of fungus 16:(Redirected from 2275: 2233: 2232: 2220: 2219: 2210: 2209: 2197: 2196: 2194:NHMSYS0020535955 2184: 2183: 2171: 2170: 2158: 2157: 2145: 2144: 2132: 2131: 2119: 2118: 2106: 2105: 2093: 2092: 2091: 2078: 2077: 2076: 2050: 2049: 2037: 2036: 2027: 2026: 2014: 2013: 2011:NHMSYS0020535956 2001: 2000: 1988: 1987: 1975: 1974: 1962: 1961: 1949: 1948: 1936: 1935: 1934: 1904: 1894: 1879: 1878: 1868: 1851:(6): 2126–2133. 1836: 1830: 1829: 1797: 1791: 1790: 1780: 1756: 1750: 1749: 1729: 1723: 1722: 1686: 1680: 1679: 1669: 1641: 1635: 1634: 1624: 1596: 1590: 1589: 1561: 1555: 1554: 1544: 1516: 1510: 1509: 1485: 1479: 1478: 1438: 1432: 1431: 1411: 1405: 1404: 1384: 1378: 1377: 1357: 1351: 1350: 1334: 1328: 1327: 1311: 1305: 1304: 1288: 1282: 1281: 1279: 1255: 1249: 1248: 1236: 1230: 1229: 1219: 1202:(1): e00428–12. 1187: 1181: 1180: 1178: 1177: 1166: 1160: 1159: 1115: 1102: 1101: 1090: 1084: 1083: 1050: 1044: 1043: 1033: 1007: 998: 992: 991: 981: 949: 943: 942: 932: 908: 902: 901: 891: 859: 850: 849: 847: 846: 831: 825: 824: 788: 749:formae speciales 656:" (corrected to 434:, who described 377:silent infection 284:Taphrinomycotina 282:, belong to the 171: 117:Pneumocystidales 68: 67: 54:cysts in tissue 46: 32: 21: 2283: 2282: 2278: 2277: 2276: 2274: 2273: 2272: 2258:Parasitic fungi 2243: 2242: 2241: 2236: 2228: 2223: 2215: 2213: 2205: 2200: 2192: 2187: 2179: 2174: 2166: 2161: 2153: 2148: 2140: 2135: 2127: 2122: 2114: 2109: 2101: 2096: 2087: 2086: 2081: 2072: 2071: 2066: 2053: 2045: 2040: 2032: 2030: 2022: 2017: 2009: 2004: 1996: 1991: 1983: 1978: 1970: 1965: 1957: 1952: 1944: 1939: 1930: 1929: 1924: 1911: 1887: 1882: 1838: 1837: 1833: 1799: 1798: 1794: 1758: 1757: 1753: 1731: 1730: 1726: 1703:10.2307/3762163 1688: 1687: 1683: 1643: 1642: 1638: 1598: 1597: 1593: 1563: 1562: 1558: 1529:Clin Infect Dis 1518: 1517: 1513: 1487: 1486: 1482: 1440: 1439: 1435: 1413: 1412: 1408: 1386: 1385: 1381: 1359: 1358: 1354: 1336: 1335: 1331: 1313: 1312: 1308: 1290: 1289: 1285: 1257: 1256: 1252: 1238: 1237: 1233: 1189: 1188: 1184: 1175: 1173: 1172:. Pgp.cchmc.org 1168: 1167: 1163: 1117: 1116: 1105: 1092: 1091: 1087: 1079:Théodore Lecard 1052: 1051: 1047: 1016:(3): 506a–506. 1005: 1000: 999: 995: 951: 950: 946: 917:Clin Infect Dis 910: 909: 905: 861: 860: 853: 844: 842: 833: 832: 828: 790: 789: 782: 778: 722:P. wakefieldiae 696:. Every tested 546: 493: 412: 362: 356: 304: 248: 178: 173: 167: 154: 62: 28: 23: 22: 15: 12: 11: 5: 2281: 2279: 2271: 2270: 2268:Fungus species 2265: 2260: 2255: 2245: 2244: 2238: 2237: 2235: 2234: 2221: 2211: 2198: 2185: 2172: 2159: 2146: 2133: 2120: 2107: 2094: 2079: 2063: 2061: 2055: 2054: 2052: 2051: 2038: 2028: 2015: 2002: 1989: 1976: 1963: 1950: 1937: 1921: 1919: 1913: 1912: 1907: 1901: 1900: 1886: 1885:External links 1883: 1881: 1880: 1831: 1812:(5): 708–726. 1792: 1771:(6): 853–871. 1751: 1724: 1697:(3): 429–438. 1681: 1636: 1615:(6): 735–744. 1591: 1556: 1542:10.1086/498150 1535:(12): 1752–5. 1511: 1480: 1433: 1406: 1379: 1370:Casop Lék Cesk 1352: 1329: 1306: 1283: 1270:(2): 159–218. 1250: 1231: 1182: 1161: 1103: 1085: 1045: 993: 944: 930:10.1086/649868 923:(3): 347–353. 903: 851: 826: 779: 777: 774: 728:from rabbits. 590:after Carini. 576:Antonio Carini 560:Chagas disease 545: 542: 532:The genome of 492: 486: 411: 408: 355: 352: 338:, followed by 324:binary fission 303: 300: 278:), which like 247: 244: 228:human pathogen 198: 197: 196: 195: 187: 186: 180: 179: 174: 163: 162: 156: 155: 148: 146: 142: 141: 134: 130: 129: 124: 120: 119: 114: 110: 109: 104: 100: 99: 94: 90: 89: 84: 80: 79: 74: 70: 69: 56: 55: 48: 47: 39: 38: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2280: 2269: 2266: 2264: 2261: 2259: 2256: 2254: 2251: 2250: 2248: 2231: 2226: 2222: 2218: 2212: 2208: 2203: 2199: 2195: 2190: 2186: 2182: 2177: 2173: 2169: 2164: 2160: 2156: 2151: 2147: 2143: 2138: 2134: 2130: 2125: 2121: 2117: 2112: 2108: 2104: 2099: 2095: 2090: 2084: 2080: 2075: 2069: 2065: 2064: 2062: 2060: 2056: 2048: 2043: 2039: 2035: 2029: 2025: 2020: 2016: 2012: 2007: 2003: 1999: 1994: 1990: 1986: 1981: 1977: 1973: 1968: 1964: 1960: 1955: 1951: 1947: 1942: 1938: 1933: 1927: 1923: 1922: 1920: 1918: 1914: 1910: 1905: 1898: 1893: 1889: 1888: 1884: 1876: 1872: 1867: 1862: 1858: 1854: 1850: 1846: 1842: 1835: 1832: 1827: 1823: 1819: 1815: 1811: 1807: 1803: 1796: 1793: 1788: 1784: 1779: 1774: 1770: 1766: 1762: 1755: 1752: 1747: 1743: 1739: 1735: 1728: 1725: 1720: 1716: 1712: 1708: 1704: 1700: 1696: 1692: 1685: 1682: 1677: 1673: 1668: 1663: 1659: 1655: 1651: 1649: 1640: 1637: 1632: 1628: 1623: 1618: 1614: 1610: 1606: 1604: 1595: 1592: 1587: 1583: 1579: 1575: 1571: 1567: 1560: 1557: 1552: 1548: 1543: 1538: 1534: 1530: 1526: 1524: 1515: 1512: 1507: 1503: 1499: 1495: 1491: 1484: 1481: 1476: 1472: 1468: 1464: 1460: 1456: 1452: 1448: 1444: 1437: 1434: 1429: 1425: 1421: 1417: 1410: 1407: 1402: 1398: 1394: 1390: 1383: 1380: 1375: 1371: 1367: 1363: 1356: 1353: 1348: 1344: 1340: 1333: 1330: 1325: 1321: 1317: 1310: 1307: 1302: 1298: 1294: 1287: 1284: 1278: 1273: 1269: 1265: 1261: 1254: 1251: 1246: 1242: 1235: 1232: 1227: 1223: 1218: 1213: 1209: 1205: 1201: 1197: 1193: 1186: 1183: 1171: 1165: 1162: 1157: 1153: 1149: 1145: 1141: 1137: 1133: 1129: 1125: 1121: 1114: 1112: 1110: 1108: 1104: 1099: 1095: 1089: 1086: 1082: 1080: 1076: 1072: 1068: 1065: 1061: 1055: 1049: 1046: 1041: 1037: 1032: 1027: 1023: 1019: 1015: 1011: 1004: 997: 994: 989: 985: 980: 975: 971: 967: 963: 959: 955: 948: 945: 940: 936: 931: 926: 922: 918: 914: 907: 904: 899: 895: 890: 885: 881: 877: 873: 869: 865: 858: 856: 852: 841:on 2013-03-18 840: 836: 830: 827: 822: 818: 814: 810: 806: 802: 798: 794: 787: 785: 781: 775: 773: 770: 766: 762: 758: 754: 750: 746: 742: 738: 734: 729: 727: 726:P. oryctolagi 723: 719: 715: 712:from humans, 711: 707: 703: 699: 695: 691: 687: 683: 679: 675: 671: 667: 664:in humans as 663: 659: 655: 651: 647: 643: 639: 635: 631: 627: 623: 619: 615: 611: 607: 603: 599: 595: 591: 589: 585: 581: 577: 573: 569: 565: 561: 557: 556: 551: 550:Carlos Chagas 543: 541: 539: 535: 528: 523: 519: 517: 513: 509: 505: 501: 497: 490: 487: 485: 483: 478: 474: 472: 468: 464: 460: 456: 452: 448: 444: 439: 437: 433: 429: 425: 421: 417: 409: 407: 405: 401: 397: 393: 389: 385: 380: 378: 374: 370: 366: 361: 353: 351: 349: 345: 341: 337: 333: 329: 325: 321: 317: 313: 309: 301: 299: 297: 293: 289: 285: 281: 277: 276: 271: 267: 263: 262: 257: 253: 245: 243: 241: 238:was known as 237: 233: 229: 225: 223: 218: 215:of the genus 214: 210: 206: 205: 194: 191: 190: 188: 185: 181: 177: 172: 170: 164: 161: 160:Binomial name 157: 153: 152: 147: 144: 143: 140: 139: 135: 132: 131: 128: 125: 122: 121: 118: 115: 112: 111: 108: 105: 102: 101: 98: 95: 92: 91: 88: 85: 82: 81: 78: 75: 72: 71: 66: 61: 57: 53: 49: 45: 40: 37: 33: 30: 19: 2058: 1916: 1848: 1844: 1834: 1809: 1805: 1802:Pneumocystis 1801: 1795: 1768: 1764: 1754: 1737: 1733: 1727: 1694: 1690: 1684: 1657: 1654:Microbiology 1653: 1647: 1639: 1612: 1608: 1603:Pneumocystis 1602: 1594: 1569: 1565: 1559: 1532: 1528: 1522: 1514: 1497: 1493: 1489: 1483: 1450: 1446: 1442: 1436: 1419: 1415: 1409: 1400: 1396: 1392: 1388: 1382: 1373: 1369: 1365: 1361: 1355: 1346: 1342: 1339:Pneumocystis 1338: 1332: 1323: 1319: 1315: 1309: 1300: 1296: 1292: 1286: 1267: 1263: 1253: 1244: 1240: 1234: 1199: 1195: 1185: 1174:. Retrieved 1164: 1131: 1127: 1123: 1120:Pneumocystis 1119: 1097: 1088: 1074: 1070: 1064:substantival 1059: 1057: 1048: 1013: 1009: 996: 964:(9): 891–6. 961: 957: 947: 920: 916: 906: 871: 867: 843:. Retrieved 839:the original 829: 796: 792: 769:Pneumocystis 768: 764: 760: 756: 752: 748: 740: 737:Pneumocystis 736: 732: 730: 725: 721: 717: 713: 710:P. jirovecii 709: 702:Pneumocystis 701: 686:Pneumocystis 685: 678:Pneumocystis 677: 673: 670:P. jirovecii 669: 666:P. jirovecii 665: 661: 658:P. jirovecii 657: 653: 646:Pneumocystis 645: 642:Pneumocystis 641: 629: 626:Otto Jírovec 621: 613: 594:Pneumocystis 593: 592: 587: 572:Pneumocystis 571: 566:, a form of 563: 553: 547: 534:P. jirovecii 533: 531: 527:P. jirovecii 526: 515: 512:P. jirovecii 511: 507: 504:Pneumocystis 503: 500:P. jirovecii 499: 496:Pneumocystis 495: 494: 489:Pneumocystis 488: 481: 479: 475: 470: 466: 463:Pneumocystis 462: 459:P. jirovecii 458: 454: 446: 440: 436:Pneumocystis 435: 432:Otto Jirovec 428:Pneumocystis 427: 423: 415: 413: 410:Nomenclature 381: 365:Pneumocystis 364: 363: 330:, a form of 328:homothallism 308:P. jirovecii 307: 305: 302:Homothallism 280:Pneumocystis 279: 273: 266:Pneumocystis 265: 259: 252:Pneumocystis 251: 249: 239: 236:P. jirovecii 235: 222:Pneumocystis 221: 217:Pneumocystis 216: 208: 207:(previously 203: 202: 201: 192: 168: 166: 150: 149: 138:Pneumocystis 137: 52:P. jirovecii 51: 35: 29: 2083:Wikispecies 1422:(1): 1–21. 1134:(1): 2–11. 720:from mice, 568:trypanosome 471:P. jiroveci 467:P. jiroveci 400:pentamidine 270:trophozoite 176:J.K.Frenkel 2253:Ascomycota 2247:Categories 1572:(1): 3–5. 1447:Pediatrics 1247:: 120–122. 1176:2013-03-26 845:2013-03-26 776:References 741:P. carinii 733:P. carinii 714:P. carinii 706:co-evolved 690:Ascomycota 682:protozoans 674:P. carinii 662:P. carinii 630:P. carinii 628:reported " 622:P. carinii 614:P. carinii 516:P. carinii 508:P. carinii 482:P. carinii 348:ascospores 240:P. carinii 209:P. carinii 97:Ascomycota 93:Division: 1734:Mycologia 1691:Mycologia 1609:Syst Biol 1500:: 13–27. 1376:: 1121–4. 1326:: 658–61. 718:P. murina 650:antigenic 480:The name 256:protozoan 246:Lifecycle 224:pneumonia 145:Species: 83:Kingdom: 77:Eukaryota 2176:MycoBank 2168:10730690 2137:Fungorum 2103:60022106 2098:AusFungi 2074:Q2099992 2068:Wikidata 1993:MycoBank 1967:Fungorum 1946:60022107 1941:AusFungi 1926:Wikidata 1875:11376046 1826:18565802 1787:17064284 1719:21148866 1676:15133075 1631:14668114 1586:17182335 1551:16288399 1475:19507186 1467:13419426 1428:13051050 1349:: 301–9. 1226:23269827 1156:38119833 1148:16441572 1075:lecardii 1067:epithets 1040:19239784 988:12194762 939:20047487 898:29463658 813:17051209 638:neonates 288:amoeboid 184:Synonyms 123:Family: 73:Domain: 2155:2610979 1985:2610978 1932:Q134478 1740:: 268. 1711:3762163 1217:3531804 1031:2681121 979:2732539 889:5821091 821:4302864 765:carinii 757:hominis 698:primate 608:in the 606:species 602:autopsy 544:History 404:dapsone 340:meiosis 320:haploid 312:asexual 296:meiosis 261:ex vivo 133:Genus: 113:Order: 103:Class: 2230:352919 2214:NZOR: 2181:446182 2142:446182 2129:PNCCCA 2047:405725 2031:NZOR: 1998:450384 1972:450385 1959:200101 1873:  1863:  1824:  1785:  1717:  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1018:doi 974:PMC 966:doi 925:doi 884:PMC 876:doi 801:doi 797:443 636:in 538:G+C 369:HIV 2249:: 2227:: 2204:: 2191:: 2178:: 2165:: 2152:: 2139:: 2126:: 2113:: 2100:: 2085:: 2070:: 2044:: 2021:: 2008:: 1995:: 1982:: 1969:: 1956:: 1943:: 1928:: 1869:. 1859:. 1849:39 1847:. 1843:. 1820:. 1808:. 1781:. 1769:30 1767:. 1763:. 1738:97 1736:. 1713:. 1705:. 1695:96 1693:. 1670:. 1656:. 1652:. 1625:. 1613:52 1611:. 1607:. 1580:. 1568:. 1545:. 1533:41 1531:. 1527:. 1498:43 1496:. 1469:. 1461:. 1451:19 1449:. 1418:. 1399:. 1374:90 1372:. 1347:22 1345:. 1322:. 1301:38 1299:. 1266:. 1262:. 1245:13 1243:. 1220:. 1210:. 1198:. 1194:. 1150:. 1142:. 1132:53 1130:. 1106:^ 1096:. 1081:). 1060:er 1056:. 1034:. 1024:. 1014:15 1012:. 1008:. 982:. 972:. 960:. 956:. 933:. 921:50 919:. 915:. 892:. 882:. 870:. 866:. 854:^ 815:. 807:. 795:. 783:^ 518:. 455:ii 398:, 379:. 242:. 1877:. 1855:: 1828:. 1816:: 1810:8 1789:. 1775:: 1748:. 1744:: 1721:. 1701:: 1678:. 1664:: 1633:. 1619:: 1588:. 1576:: 1570:7 1553:. 1539:: 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Index

Pneumocystis carinii
"P. jirovecii" cysts in tissue
Scientific classification
Edit this classification
Eukaryota
Fungi
Ascomycota
Pneumocystidomycetes
Pneumocystidales
Pneumocystidaceae
Pneumocystis
Binomial name
J.K.Frenkel
Synonyms
fungus
Pneumocystis pneumonia
human pathogen
immunocompromised hosts
protozoan
ex vivo
trophozoite
Schizosaccharomyces pombe
Taphrinomycotina
amoeboid
ascus
meiosis
asexual
sexual
haploid
binary fission

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