345:
322:
219:
244:
351:
250:
1807:
1299:
50:
358:
257:
1279:
850:
831:
180:
47:
1740:
1836:
1714:
1237:
1344:
1219:
1831:
1375:
344:
1430:
1058:
1683:
1614:
1065:
321:
1698:
1206:
1185:
1145:
1202:
243:
218:
1181:
1673:
1580:
160:
1846:
1841:
357:
256:
1602:
1426:
1419:
350:
249:
1337:
1597:
1519:
1368:
895:
168:
876:
1709:
1619:
1414:
1475:
1156:
that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of
1400:
1330:
232:
147:
1861:
1856:
1810:
1497:
1361:
1041:
990:
1020:
192:
1016:
969:
1851:
1693:
140:
40:
437:
368:
312:
267:
188:
1409:
1153:
412:
1314:
765:
760:
755:
750:
745:
740:
735:
730:
725:
720:
715:
710:
694:
689:
684:
679:
663:
658:
653:
648:
643:
638:
633:
628:
1825:
1721:
1542:
1283:
615:
172:
1688:
1657:
1607:
1590:
1537:
1490:
1310:
430:
209:
196:
1242:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1224:
National Center for
Biotechnology Information, U.S. National Library of Medicine
513:
1624:
1445:
1392:
1384:
329:
226:
176:
795:
573:
451:
396:
383:
295:
282:
184:
151:, ARTD8, BAL2, PARP-14, pART8, poly(ADP-ribose) polymerase family member 14
1255:
1105:
1100:
1705:
1089:
944:
925:
921:
1652:
1404:
1149:
1121:
907:
862:
117:
113:
109:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
1777:
1532:
1485:
1480:
1157:
1073:
817:
1298:
1792:
1787:
1782:
1772:
1765:
1760:
1755:
1750:
1745:
1735:
1730:
1585:
1549:
1470:
1465:
1460:
1450:
1125:
746:
negative regulation of interferon-gamma-mediated signaling pathway
780:
776:
1678:
1634:
1629:
1564:
1559:
1554:
1527:
1507:
1502:
1455:
1306:
1129:
164:
1357:
751:
positive regulation of interleukin-4-mediated signaling pathway
741:
negative regulation of tyrosine phosphorylation of STAT protein
736:
positive regulation of tyrosine phosphorylation of STAT protein
1440:
1435:
1141:
1353:
1256:"Entrez Gene: Poly(ADP-ribose) polymerase family member 14"
420:
1318:
585:
1160:
that perform this modification (Ame et al., 2004 ).
1666:
1645:
1573:
1518:
1391:
1034:
1009:
983:
962:
1198:
1196:
1194:
1177:
1175:
1173:
367:
266:
16:Protein-coding gene in the species Homo sapiens
1203:GRCm38: Ensembl release 89: ENSMUSG00000034422
1369:
1338:
8:
1118:Poly(ADP-ribose) polymerase family member 14
1182:GRCh38: Ensembl release 89: ENSG00000173193
1376:
1362:
1354:
1345:
1331:
1280:United States National Library of Medicine
791:
711:regulation of transcription, DNA-templated
611:
408:
307:
204:
58:
1278:This article incorporates text from the
1169:
1140:Poly(ADP-ribosyl)ation is an immediate
731:negative regulation of gene expression
18:
372:
333:
328:
271:
230:
225:
7:
1295:
1293:
654:NAD+ ADP-ribosyltransferase activity
1684:Proliferating Cell Nuclear Antigen
1615:Microhomology-mediated end joining
1031:
1006:
980:
959:
935:
912:
886:
867:
841:
822:
590:
508:
446:
425:
14:
1806:
1805:
1699:Meiotic recombination checkpoint
1297:
356:
349:
343:
320:
255:
248:
242:
217:
1146:post-translational modification
664:protein ADP-ribosylase activity
574:More reference expression data
1:
1837:Human chromosome 3 gene stubs
766:protein mono-ADP-ribosylation
721:protein poly-ADP-ribosylation
532:epithelium of small intestine
341:
240:
1581:Transcription-coupled repair
1317:. You can help Knowledge by
716:transcription, DNA-templated
634:glycosyltransferase activity
1832:Genes on human chromosome 3
1128:, is encoded by the PARP14
1878:
1603:Non-homologous end joining
1427:Nucleotide excision repair
1420:Poly ADP ribose polymerase
1292:
1801:
1238:"Mouse PubMed Reference:"
1220:"Human PubMed Reference:"
1104:
1099:
1095:
1088:
1072:
1059:Chr 3: 122.68 – 122.73 Mb
1053:
1038:
1013:
1002:
987:
966:
955:
942:
938:
919:
915:
906:
893:
889:
874:
870:
861:
848:
844:
829:
825:
816:
801:
794:
790:
774:
614:
610:
598:
593:
584:
571:
520:
511:
458:
449:
419:
411:
407:
390:
377:
340:
319:
310:
306:
289:
276:
239:
216:
207:
203:
158:
155:
145:
138:
133:
66:
61:
44:
39:
34:
30:
26:
21:
1598:Homology directed repair
1520:Homologous recombination
1066:Chr 16: 35.65 – 35.69 Mb
726:protein ADP-ribosylation
1620:Postreplication repair
1415:Uracil-DNA glycosylase
761:innate immune response
552:mucous cell of stomach
548:lumbar spinal ganglion
544:mesenteric lymph nodes
756:immune system process
335:Chromosome 16 (mouse)
1726:core protein complex
1401:Base excision repair
629:transferase activity
233:Chromosome 3 (human)
62:List of PDB id codes
35:Available structures
1498:DNA mismatch repair
560:conjunctival fornix
1847:Molecular genetics
1842:Cellular processes
1305:This article on a
1282:, which is in the
896:ENSMUSG00000034422
704:Biological process
673:Cellular component
622:Molecular function
197:PARP14 - orthologs
1819:
1818:
1694:Adaptive response
1326:
1325:
1144:damage-dependent
1115:
1114:
1111:
1110:
1084:
1083:
1049:
1048:
1028:
1027:
998:
997:
977:
976:
951:
950:
932:
931:
902:
901:
883:
882:
857:
856:
838:
837:
786:
785:
606:
605:
602:
601:
580:
579:
567:
566:
524:intestinal villus
505:
504:
403:
402:
302:
301:
129:
128:
125:
124:
45:Ortholog search:
1869:
1809:
1808:
1378:
1371:
1364:
1355:
1347:
1340:
1333:
1301:
1294:
1266:
1265:
1263:
1262:
1252:
1246:
1245:
1234:
1228:
1227:
1216:
1210:
1200:
1189:
1179:
1154:nuclear proteins
1097:
1096:
1068:
1061:
1044:
1032:
1023:
1007:
1003:RefSeq (protein)
993:
981:
972:
960:
936:
913:
887:
868:
842:
823:
792:
612:
591:
576:
516:
514:Top expressed in
509:
474:white blood cell
466:nasal epithelium
454:
452:Top expressed in
447:
426:
409:
399:
386:
375:
360:
353:
347:
336:
324:
308:
298:
285:
274:
259:
252:
246:
235:
221:
205:
199:
150:
143:
120:
59:
53:
32:
31:
19:
1877:
1876:
1872:
1871:
1870:
1868:
1867:
1866:
1822:
1821:
1820:
1815:
1797:
1667:Other/ungrouped
1662:
1641:
1569:
1514:
1410:DNA glycosylase
1393:Excision repair
1387:
1382:
1352:
1351:
1290:
1275:
1273:Further reading
1270:
1269:
1260:
1258:
1254:
1253:
1249:
1236:
1235:
1231:
1218:
1217:
1213:
1201:
1192:
1180:
1171:
1166:
1138:
1106:View/Edit Mouse
1101:View/Edit Human
1064:
1057:
1054:Location (UCSC)
1040:
1019:
1015:
989:
968:
924:
877:ENSG00000173193
770:
699:
668:
644:protein binding
572:
563:
558:
554:
550:
546:
542:
538:
534:
530:
526:
512:
501:
496:
492:
488:
484:
480:
476:
472:
470:Achilles tendon
468:
464:
450:
394:
381:
373:
363:
362:
361:
354:
334:
311:Gene location (
293:
280:
272:
262:
261:
260:
253:
231:
208:Gene location (
159:
146:
139:
68:
46:
17:
12:
11:
5:
1875:
1873:
1865:
1864:
1859:
1854:
1849:
1844:
1839:
1834:
1824:
1823:
1817:
1816:
1814:
1813:
1802:
1799:
1798:
1796:
1795:
1790:
1785:
1780:
1775:
1770:
1769:
1768:
1763:
1758:
1753:
1748:
1743:
1738:
1733:
1718:
1717:
1712:
1702:
1701:
1696:
1691:
1686:
1681:
1676:
1670:
1668:
1664:
1663:
1661:
1660:
1655:
1649:
1647:
1643:
1642:
1640:
1639:
1638:
1637:
1632:
1622:
1617:
1612:
1611:
1610:
1600:
1595:
1594:
1593:
1588:
1577:
1575:
1574:Other pathways
1571:
1570:
1568:
1567:
1562:
1557:
1552:
1547:
1546:
1545:
1535:
1530:
1524:
1522:
1516:
1515:
1513:
1512:
1511:
1510:
1505:
1495:
1494:
1493:
1488:
1483:
1478:
1473:
1468:
1463:
1458:
1453:
1448:
1443:
1438:
1424:
1423:
1422:
1417:
1412:
1397:
1395:
1389:
1388:
1383:
1381:
1380:
1373:
1366:
1358:
1350:
1349:
1342:
1335:
1327:
1324:
1323:
1302:
1274:
1271:
1268:
1267:
1247:
1229:
1211:
1190:
1168:
1167:
1165:
1162:
1137:
1134:
1113:
1112:
1109:
1108:
1103:
1093:
1092:
1086:
1085:
1082:
1081:
1079:
1077:
1070:
1069:
1062:
1055:
1051:
1050:
1047:
1046:
1036:
1035:
1029:
1026:
1025:
1011:
1010:
1004:
1000:
999:
996:
995:
985:
984:
978:
975:
974:
964:
963:
957:
953:
952:
949:
948:
940:
939:
933:
930:
929:
917:
916:
910:
904:
903:
900:
899:
891:
890:
884:
881:
880:
872:
871:
865:
859:
858:
855:
854:
846:
845:
839:
836:
835:
827:
826:
820:
814:
813:
808:
803:
799:
798:
788:
787:
784:
783:
772:
771:
769:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
713:
707:
705:
701:
700:
698:
697:
692:
687:
682:
676:
674:
670:
669:
667:
666:
661:
659:enzyme binding
656:
651:
646:
641:
636:
631:
625:
623:
619:
618:
608:
607:
604:
603:
600:
599:
596:
595:
588:
582:
581:
578:
577:
569:
568:
565:
564:
562:
561:
557:
553:
549:
545:
541:
537:
533:
529:
525:
521:
518:
517:
506:
503:
502:
500:
499:
495:
491:
487:
483:
479:
475:
471:
467:
463:
459:
456:
455:
443:
442:
434:
423:
417:
416:
413:RNA expression
405:
404:
401:
400:
392:
388:
387:
379:
376:
371:
365:
364:
355:
348:
342:
338:
337:
332:
326:
325:
317:
316:
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
229:
223:
222:
214:
213:
201:
200:
157:
153:
152:
144:
136:
135:
131:
130:
127:
126:
123:
122:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1874:
1863:
1860:
1858:
1855:
1853:
1850:
1848:
1845:
1843:
1840:
1838:
1835:
1833:
1830:
1829:
1827:
1812:
1804:
1803:
1800:
1794:
1791:
1789:
1786:
1784:
1781:
1779:
1776:
1774:
1771:
1767:
1764:
1762:
1759:
1757:
1754:
1752:
1749:
1747:
1744:
1742:
1739:
1737:
1734:
1732:
1729:
1728:
1727:
1723:
1722:FANC proteins
1720:
1719:
1716:
1713:
1711:
1707:
1704:
1703:
1700:
1697:
1695:
1692:
1690:
1687:
1685:
1682:
1680:
1677:
1675:
1672:
1671:
1669:
1665:
1659:
1656:
1654:
1651:
1650:
1648:
1644:
1636:
1633:
1631:
1628:
1627:
1626:
1623:
1621:
1618:
1616:
1613:
1609:
1606:
1605:
1604:
1601:
1599:
1596:
1592:
1589:
1587:
1584:
1583:
1582:
1579:
1578:
1576:
1572:
1566:
1563:
1561:
1558:
1556:
1553:
1551:
1548:
1544:
1543:RecQ helicase
1541:
1540:
1539:
1536:
1534:
1531:
1529:
1526:
1525:
1523:
1521:
1517:
1509:
1506:
1504:
1501:
1500:
1499:
1496:
1492:
1489:
1487:
1484:
1482:
1479:
1477:
1474:
1472:
1469:
1467:
1464:
1462:
1459:
1457:
1454:
1452:
1449:
1447:
1444:
1442:
1439:
1437:
1434:
1433:
1432:
1428:
1425:
1421:
1418:
1416:
1413:
1411:
1408:
1407:
1406:
1402:
1399:
1398:
1396:
1394:
1390:
1386:
1379:
1374:
1372:
1367:
1365:
1360:
1359:
1356:
1348:
1343:
1341:
1336:
1334:
1329:
1328:
1322:
1320:
1316:
1312:
1308:
1303:
1300:
1296:
1291:
1288:
1287:
1285:
1284:public domain
1281:
1272:
1257:
1251:
1248:
1243:
1239:
1233:
1230:
1225:
1221:
1215:
1212:
1208:
1204:
1199:
1197:
1195:
1191:
1187:
1183:
1178:
1176:
1174:
1170:
1163:
1161:
1159:
1155:
1151:
1147:
1143:
1135:
1133:
1131:
1127:
1123:
1119:
1107:
1102:
1098:
1094:
1091:
1087:
1080:
1078:
1075:
1071:
1067:
1063:
1060:
1056:
1052:
1045:
1043:
1037:
1033:
1030:
1024:
1022:
1018:
1012:
1008:
1005:
1001:
994:
992:
986:
982:
979:
973:
971:
965:
961:
958:
956:RefSeq (mRNA)
954:
947:
946:
941:
937:
934:
928:
927:
923:
918:
914:
911:
909:
905:
898:
897:
892:
888:
885:
879:
878:
873:
869:
866:
864:
860:
853:
852:
847:
843:
840:
834:
833:
828:
824:
821:
819:
815:
812:
809:
807:
804:
800:
797:
793:
789:
782:
778:
773:
767:
764:
762:
759:
757:
754:
752:
749:
747:
744:
742:
739:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
708:
706:
703:
702:
696:
693:
691:
688:
686:
683:
681:
678:
677:
675:
672:
671:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
626:
624:
621:
620:
617:
616:Gene ontology
613:
609:
597:
592:
589:
587:
583:
575:
570:
559:
555:
551:
547:
543:
539:
535:
531:
527:
523:
522:
519:
515:
510:
507:
497:
493:
489:
485:
481:
477:
473:
469:
465:
461:
460:
457:
453:
448:
445:
444:
441:
439:
435:
433:
432:
428:
427:
424:
422:
418:
414:
410:
406:
398:
393:
389:
385:
380:
374:16|16 B3
370:
366:
359:
352:
346:
339:
331:
327:
323:
318:
314:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
234:
228:
224:
220:
215:
211:
206:
202:
198:
194:
190:
186:
182:
178:
174:
170:
166:
162:
154:
149:
142:
137:
132:
121:
119:
115:
111:
107:
103:
99:
95:
91:
87:
83:
79:
75:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
1725:
1706:DNA helicase
1689:8-Oxoguanine
1658:SOS response
1538:RecF pathway
1491:Excinuclease
1319:expanding it
1311:chromosome 3
1304:
1289:
1277:
1276:
1259:. Retrieved
1250:
1241:
1232:
1223:
1214:
1139:
1117:
1116:
1042:NP_001034619
1039:
1014:
991:NM_001039530
988:
967:
943:
920:
894:
875:
849:
830:
810:
805:
649:NAD+ binding
436:
429:
294:122,730,840
281:122,680,839
156:External IDs
67:
1021:NP_060024.2
639:RNA binding
528:Paneth cell
486:granulocyte
462:sural nerve
395:35,691,914
382:35,653,244
134:Identifiers
1862:Senescence
1857:DNA repair
1826:Categories
1646:Regulation
1625:Photolyase
1385:DNA repair
1261:2016-03-02
1209:, May 2017
1188:, May 2017
1164:References
1152:and other
556:white pulp
536:lymph node
498:lymph node
440:(ortholog)
177:HomoloGene
1466:XPG/ERCC5
1451:XPD/ERCC2
1309:on human
1124:that, in
1017:NP_060024
970:NM_017554
796:Orthologs
695:cytoplasm
185:GeneCards
1852:Mutation
1811:Category
1461:XPF/DDB1
1456:XPE/DDB1
1205:–
1184:–
1150:histones
1136:Function
1090:Wikidata
775:Sources:
680:membrane
494:appendix
478:monocyte
1653:SOS box
1405:AP site
1207:Ensembl
1186:Ensembl
1158:enzymes
1122:protein
908:UniProt
863:Ensembl
802:Species
781:QuickGO
690:cytosol
685:nucleus
540:jejunum
490:decidua
415:pattern
173:1919489
141:Aliases
1778:FANCD2
1773:FANCD1
1533:RecBCD
1486:RAD23B
1481:RAD23A
1126:humans
1076:search
1074:PubMed
945:Q2EMV9
926:Q8N546
922:Q460N5
851:547253
818:Entrez
586:BioGPS
482:spleen
273:3q21.1
189:PARP14
165:610028
148:PARP14
22:PARP14
1793:FANCN
1788:FANCJ
1783:FANCI
1766:FANCM
1761:FANCL
1756:FANCG
1751:FANCF
1746:FANCE
1741:FANCC
1736:FANCB
1731:FANCA
1591:ERCC8
1586:ERCC6
1550:RAD51
1471:ERCC1
1313:is a
1120:is a
832:54625
811:Mouse
806:Human
777:Amigo
438:Mouse
431:Human
378:Start
313:Mouse
277:Start
210:Human
181:19697
1679:PcrA
1635:CRY2
1630:CRY1
1565:LexA
1560:Slx4
1555:Sgs1
1528:RecA
1508:MSH2
1503:MLH1
1431:ERCC
1315:stub
1307:gene
1130:gene
421:Bgee
369:Band
330:Chr.
268:Band
227:Chr.
161:OMIM
118:4PY4
114:4F1Q
110:4F1L
106:4D86
102:4ABL
98:4ABK
94:3VFQ
90:3SMJ
86:3SMI
82:3SE2
78:3Q71
74:3Q6Z
70:3GOY
51:RCSB
48:PDBe
1715:WRN
1710:BLM
1674:Ogt
1476:RPA
1446:XPC
1441:XPB
1436:XPA
1148:of
1142:DNA
594:n/a
391:End
290:End
193:OMA
169:MGI
41:PDB
1828::
1724::
1708::
1608:Ku
1240:.
1222:.
1193:^
1172:^
1132:.
779:/
397:bp
384:bp
296:bp
283:bp
191:;
187::
183:;
179::
175:;
171::
167:;
163::
116:,
112:,
108:,
104:,
100:,
96:,
92:,
88:,
84:,
80:,
76:,
72:,
1429:/
1403:/
1377:e
1370:t
1363:v
1346:e
1339:t
1332:v
1321:.
1286:.
1264:.
1244:.
1226:.
315:)
212:)
195::
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