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Povidone-iodine

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501: 478: 671: 783:), and other opportunistic pathogens. Its ability to harbor such microbes further underscores the importance of using sterile products in any clinical setting. Since these bacteria are resistant to povidone iodine, statements that bacteria do not develop resistance to PVP-I, should be regarded with great caution: some bacteria are intrinsically resistant to a range of biocides including povidone-iodine. 967: 4441: 1103:, and is also effective against yeasts, molds, fungi, viruses, and protozoans. Drawbacks to its use in the form of aqueous solutions include irritation at the site of application, toxicity, and the staining of surrounding tissues. These deficiencies were overcome by the discovery and use of PVP-I, in which the iodine is carried in a 1131: 769:
Because of these critical indications, only sterile povidone-iodine should be used in most cases. Non-sterile product can be appropriate in limited circumstances in which people have intact, healthy skin that will not be compromised or cut. The non-sterile form of Povidone iodine has a long history
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or mixed infections. For these purposes PVP-I has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% povidone-iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is
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Iodine is absorbed into the body to various degrees, depending on application area and condition of the skin. As such, it interacts with diagnostic tests of the thyroid gland such as radioiodine diagnostics, as well as with various diagnostic agents used on the urine and stool, for example
1986: 830:. It is currently unclear whether PVP-I is more effective in reducing the number of cases of conjunctivitis in neonates over other methods. PVP-I appears to be very suitable for this purpose because, unlike other substances, it is also efficient against 2049:
Three methods are used to obtain povidone–iodine: exposing the polymer to iodine vapors , mixing PVP and iodine solutions , and heating dry PVP and iodine samples at 80–90°C until the titrated iodine concentration is constant
1902: 3767: 643:. The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. It works by releasing iodine which results in the death of a range of 1605:
Slater K, Cooke M, Fullerton F, Whitby M, Hay J, Lingard S, et al. (September 2020). "Peripheral intravenous catheter needleless connector decontamination study-Randomized controlled trial".
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Wong RH, Wong VW, Hung EC, Lee PY, Ng CS, Wan IY, et al. (2011). "Topical application of povidone-iodine before wound closure is associated with significant increase in serum iodine level".
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in 1811, it has been broadly used for the prevention and treatment of skin infections, as well as the treatment of wounds. Iodine has been recognized as an effective broad-spectrum
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Consequently, PVP-I has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in
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dressing. The rate of release of the iodine in the PVP-I is heavily dependent on the hydrogel composition: it increases with more CMC/PVA and decreases with more gelatin.
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Research has previously found that the polymer polyvinylpyrrolidone (PVP, povidone) can coil around individual carbon nanotubes to make them water-soluble.
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Povidone-iodine has found application in the field of nanomaterials. A wound-healing application has been developed which employs a mat of single wall
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PVP-I was discovered in 1955, at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out tests
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in a compound of more than 31,600 ppm of total iodine atoms. All the toxic and staining effects of PVP-I is due to the inactive iodine only.
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is almost twice as effective in preventing infection after surgery with a similar to lower risk of adverse events, and the combination of
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Slater K, Fullerton F, Cooke M, Snell S, Rickard CM (September 2018). "Needleless connector drying time-how long does it take?".
1891:(in German) (62nd ed.). Vienna: Österreichischer Apothekerverlag (Austrian pharmacist publishing company). pp. 983–5. 1820:
Najafi Bi R, Samani SM, Pishva N, Moheimani F (2003). "Formulation and Clinical Evaluation of Povidone-Iodine Ophthalmic Drop".
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Wong RH, Hung EC, Wong VW, Wan IY, Ng CS, Wan S, et al. (2009). "Povidone-iodine wound irrigation: A word of caution".
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Niedner R (1997). "Cytotoxicity and sensitization of povidone-iodine and other frequently used anti-infective agents".
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Free iodine, slowly liberated from the povidone-iodine (PVP-I) complex in solution, kills cells through iodination of
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because of incessant pleural effusions). For this purpose, povidone-iodine is equally effective and safe as
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Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of
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and proteins such as enzymes, rendering them (and itself) ineffective. It also reacts with many
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to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than
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and membrane compounds. This agent exhibits a broad range of microbiocidal activity against
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used to clean skin prior to surgery is better than any formulation of povidone-iodine.
844: 644: 2365: 2211:"Large area-aligned arrays from direct deposition of single-wall carbon nanotube inks" 948:, as well as with many metals, making it unsuitable for disinfecting metal piercings. 600:
Side effects include skin irritation and sometimes swelling. If used on large wounds,
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form and the concentration of free iodine is very low. The product thus serves as an
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Schematic of povidone-iodine complex wrapping a single wall carbon nanotube (black).
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Fleischer W, Reimer K (1997). "Povidone-iodine in antisepsis--state of the art".
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Kramer A, Dissemond J, Kim S, Willy C, Mayer D, Papke R, et al. (2018).
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World Health Organization model list of essential medicines: 22nd list (2021)
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to the target cells. Most commonly used 10% PVP-I delivers about 1–3 ppm of I
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Simmons TJ, Lee SH, Park TJ, Hashim DP, Ajayan PM, Linhardt RJ (2009).
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Wade RG, Burr NE, McCauley G, Bourke G, Efthimiou O (September 2020).
1130: 597:. It may be applied to the skin as a liquid, an ointment or a powder. 4326: 4216: 3224: 2726: 2557: 2503: 2484: 1449: 1447: 1092: 1033: 933: 861: 730: 726: 640: 612:
may occur. It is not recommended in women who are less than 32 weeks
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Makhayeva DN, Irmukhametova GS, Khutoryanskiy VV (January 2020).
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Makhayeva DN, Irmukhametova GS, Khutoryanskiy VV (2023-11-08).
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Rose H, Baldwin A, Dowson CG, Mahenthiralingam E (March 2009).
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Povidone-iodine came into commercial use in 1955. It is on the
247: 99: 839: 1002:). It is synthesized by mixing the PVP polymer with iodine (I 1728:"Biocide susceptibility of the Burkholderia cepacia complex" 462: 900:) and other diseases of the thyroid, after treatment with 2209:
Simmons TJ, Hashim D, Vajtai R, Ajayan PM (August 2007).
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Antiseptic activity of PVP-I is because of free iodine (I
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Martin I, Sawatzky P, Liu G, Mulvey MR (February 2015).
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in very low concentration is significantly superior for
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World Health Organization's List of Essential Medicines
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Agarwal R, Khan A, Aggarwal AN, Gupta D (March 2012).
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of 2.5% concentration can be used for prevention of
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Stuart MC, Kouimtzi M, Hill SR (eds.). 297: 1957:Ullmann's Encyclopedia of Industrial Chemistry 1318:Encyclopedia of polymer science and technology 1252:British National Formulary (BNF), 69th Edition 4477:World Health Organization essential medicines 4201: 3761: 3031: 2878: 2381: 8: 2106: 2104: 1822:Iranian Journal of Pharmaceuticical Research 1779:"Neisseria gonorrhoeae in Canada: 2009-2013" 1552:"Consensus on Wound Antisepsis: Update 2018" 108: 21: 2317:European Journal of Cardio-Thoracic Surgery 1009:It is soluble in cold and mild-warm water, 217: 4208: 4194: 4186: 3963: 3768: 3754: 3746: 3038: 3024: 3016: 2885: 2871: 2863: 2388: 2374: 2366: 1495:Chen S, Chen JW, Guo B, Xu CS (May 2020). 499: 476: 29: 2328: 2311:Wong RH, Ng CS, Underwood MJ (May 2012). 2185: 2034: 2024: 1856: 1804: 1794: 1753: 1743: 1732:The Journal of Antimicrobial Chemotherapy 1471: 1405: 1196: 1194: 1192: 1190: 944:compounds, giving the corrosive compound 378: 2215:Journal of the American Chemical Society 1311: 1309: 965: 892:PVP-I is contraindicated in people with 686:. It may be used in first aid for minor 280:2-Pyrrolidinone, 1-ethenyl-, homopolymer 4436: 2313:"Iodine pleurodesis--a word of caution" 1245: 1243: 1241: 1239: 1237: 1235: 1233: 1186: 674:Wound area covered in povidone-iodine. 472: 342: 277: 1905:from the original on 22 February 2022. 1845:The Indian Journal of Medical Research 1277:from the original on 22 February 2022. 490: 20: 3150:Selenium disulfide (selenium sulfide) 1650:American Journal of Infection Control 1607:American Journal of Infection Control 1400:. Geneva: World Health Organization. 1360:. John Wiley & Sons. p. 68. 970:Structure of povidone-iodine complex. 790:) and PVP-I only acts as carrier of I 777: 741:; for the treatment of infections in 445: 425: 81: 7: 2361:. U.S. National Library of Medicine. 1432:from the original on 13 January 2017 205: 193: 181: 169: 157: 144: 405: 398: 313: 59:Betadine, Wokadine, Pyodine, others 2567:Iodine/octylphenoxypolyglycolether 1783:Canada Communicable Disease Report 1079:. These hydrogels can be used for 14: 3160:Zinc pyrithione (pyrithione zinc) 4439: 2668:Didecyldimethylammonium chloride 2296:10.1111/j.1744-1633.2011.00547.x 2267:10.1111/j.1744-1633.2009.00461.x 1556:Skin Pharmacology and Physiology 1382:from the original on 2017-01-13. 1343:from the original on 2017-01-13. 928:The iodine in PVP-I reacts with 818:, especially if it is caused by 770:of intrinsic contamination with 3120:Ciclopirox olamine (ciclopirox) 2759:Isopropanol (isopropyl alcohol) 2187:10.1016/j.eurpolymj.2023.112573 1989:from the original on 2022-02-22 654:. Povidone-iodine is available 67:polyvidone iodine, iodopovidone 2810:Chloramine-T (tosylchloramide) 1796:10.1002/14651858.CD001862.pub3 1006:), allowing the two to react. 876:There is strong evidence that 35:Povidone-iodine applied to an 1: 2621:Quaternary ammonium compounds 1354:Sneader W (31 October 2005). 920:rate to the product is 0.7%. 2140:10.1016/j.carbon.2009.02.005 1473:10.1097/SLA.0000000000004076 2013:Review Journal of Chemistry 1091:Following the discovery of 4493: 2815:Octenidine dihydrochloride 1662:10.1016/j.ajic.2018.05.007 1619:10.1016/j.ajic.2019.11.030 1513:10.1007/s00268-020-05384-7 1410:. WHO/MHP/HPS/EML/2021.02. 508:Chemical and physical data 3453:Potassium channel openers 2823: 2754:Propanol (propyl alcohol) 2077:Drug Discovery: A History 2075:Walter S (23 June 2005). 2026:10.1134/S2079978020010033 1394:World Health Organization 1357:Drug Discovery: A History 1289:"Povidone iodine topical" 1202:World Health Organization 1059:PVP-I can be loaded into 766:excessively slow to dry. 550: 268: 83:Consumer Drug Information 28: 2166:European Polymer Journal 1965:10.1002/14356007.w08_w03 1951:Kutscher B (June 2000). 1501:World Journal of Surgery 1206:WHO Model Formulary 2008 1063:, which can be based on 906:dermatitis herpetiformis 4169:Lactobacillus fermentum 3650:Glycopyrronium tosylate 3565:Aminobenzoate potassium 3497:5α-Reductase inhibitors 3445:Topilutamide (fluridil) 3390:5α-Reductase inhibitors 3365:Topical corticosteroids 3262:Topical corticosteroids 2921:Aluminium chlorohydrate 2764:Ethanol (ethyl alcohol) 2359:Drug Information Portal 1065:carboxymethyl cellulose 816:neonatal conjunctivitis 4297:Dichlorobenzyl alcohol 4238:Acriflavinium chloride 3878:Diiodohydroxyquinoline 3645:Glycopyrronium bromide 3488:Hair growth inhibitors 3175:Calcineurin inhibitors 2971:Phenylmercuric nitrate 2780:Potassium permanganate 2687:Mercuric amidochloride 1135: 971: 679: 678:has also been applied. 4317:Myristyl-benzalkonium 3234:urea-containing cream 2692:Phenylmercuric borate 2634:Benzethonium chloride 2063:U.S. patent 2,739,922 1885:Jasek W, ed. (2007). 1133: 974:Povidone-iodine is a 969: 908:(Duhring's disease). 904:, and in people with 827:Chlamydia trachomatis 821:Neisseria gonorrhoeae 673: 627:Povidone-iodine is a 3710:Pregnenolone acetate 3411:Saw palmetto extract 2663:Benzoxonium chloride 2577:Diiodohydroxypropane 2330:10.1093/ejcts/ezr137 1075:, or on crosslinked 984:polyvinylpyrrolidone 773:Burkholderia cepacia 256: / Rx-only 3527:Cyproterone acetate 3430:Cyproterone acetate 3381:Alopecia treatments 3329:Anti-inflammatories 3110:Cetrimonium bromide 3081:Cyproterone acetate 2894:Medicated dressings 2785:Sodium hypochlorite 2423:Ethacridine lactate 2178:2023EurPJ.20112573M 2132:2009Carbo..47.1561S 1069:poly(vinyl alcohol) 1019:polyethylene glycol 781:Pseudomonas cepacia 712:sodium hypochlorite 25: 16:Antiseptic solution 2850:Never to phase III 1924:(Suppl 2): 89–92. 1745:10.1093/jac/dkn540 1175:Tincture of iodine 1136: 1120:tincture of iodine 972: 704:tincture of iodine 680: 620:or who are taking 610:metabolic acidosis 4427: 4426: 4380:Local anesthetics 4183: 4182: 4121: 4120: 3743: 3742: 3680:Magnesium sulfate 3660:Hydrogen peroxide 3595:Calcium gluconate 3254:Lithium succinate 3249:Lithium gluconate 3145:Piroctone olamine 3013: 3012: 2860: 2859: 2800:Hydrogen peroxide 2697:Mercuric chloride 2455:Dibrompropamidine 2355:"Povidone-iodine" 2284:Surgical Practice 2255:Surgical Practice 2227:10.1021/ja073745e 2086:978-0-471-89979-2 1974:978-3-527-30385-4 1959:. pp. 1–22. 1930:10.1159/000246038 1898:978-3-85200-181-4 1705:10.1159/000246022 1568:10.1159/000481545 1460:Annals of Surgery 1367:978-0-470-01552-0 1328:978-0-470-07369-8 1262:978-0-85711-156-2 1223:978-92-4-154765-9 1036:and oxidation of 1015:isopropyl alcohol 930:hydrogen peroxide 888:Contraindications 882:denatured alcohol 716:hypochlorous acid 606:high blood sodium 589:before and after 587:skin disinfection 577:), also known as 568: 567: 458:CompTox Dashboard 251: 102: 4484: 4444: 4443: 4442: 4435: 4210: 4203: 4196: 4187: 4113:Methylrosaniline 3964: 3770: 3763: 3756: 3747: 3620:Deoxycholic acid 3610:Cromoglicic acid 3061:Anti-seborrheics 3040: 3033: 3026: 3017: 2887: 2880: 2873: 2864: 2390: 2383: 2376: 2367: 2362: 2342: 2332: 2307: 2278: 2239: 2238: 2206: 2200: 2199: 2189: 2157: 2151: 2150: 2148: 2142:. Archived from 2126:(6): 1561–1564. 2117: 2108: 2099: 2098: 2072: 2066: 2065: 2059: 2053: 2052: 2038: 2028: 2004: 1998: 1997: 1995: 1994: 1948: 1942: 1941: 1913: 1907: 1906: 1882: 1871: 1870: 1860: 1836: 1830: 1829: 1817: 1811: 1810: 1808: 1798: 1774: 1768: 1767: 1757: 1747: 1723: 1717: 1716: 1699:(Suppl 2): 3–9. 1688: 1682: 1681: 1656:(9): 1080–1081. 1645: 1639: 1638: 1613:(9): 1013–1018. 1602: 1596: 1595: 1547: 1541: 1540: 1507:(5): 1412–1424. 1492: 1486: 1485: 1475: 1466:(6): e481–e488. 1451: 1442: 1441: 1439: 1437: 1418: 1412: 1411: 1409: 1390: 1384: 1383: 1351: 1345: 1344: 1313: 1304: 1303: 1301: 1299: 1285: 1279: 1278: 1247: 1228: 1227: 1198: 1155:Cadexomer iodine 1140:carbon nanotubes 1097:Bernard Courtois 1027:Lugol's solution 1001: 1000: 999: 976:chemical complex 779: 757:associated with 743:decubitus ulcers 656:over the counter 639:, and elemental 629:chemical complex 618:thyroid problems 564: 563: 556: 503: 492: 481: 480: 466: 464: 449: 429: 409: 402: 382: 346: 326: 316: 315: 301: 249: 246: 221: 209: 197: 185: 173: 161: 148: 112: 101: 98: 85: 33: 26: 24: 4492: 4491: 4487: 4486: 4485: 4483: 4482: 4481: 4452: 4451: 4450: 4440: 4438: 4430: 4428: 4423: 4407: 4374: 4336: 4332:Povidone-iodine 4312:Hexylresorcinol 4277:Cetylpyridinium 4224: 4214: 4184: 4179: 4158:Povidone-iodine 4117: 4096: 4068: 4050: 3953: 3935: 3907: 3863: 3844: 3820:Oxytetracycline 3810:Chloramphenicol 3791: 3780:anti-infectives 3774: 3744: 3739: 3705:Povidone-iodine 3655:Hyaluronic acid 3580:Benzoylperoxide 3548: 3482: 3375: 3323: 3300: 3278:Skin lightening 3272: 3055: 3044: 3014: 3009: 2985: 2976:Povidone-iodine 2936:Cetylpyridinium 2931:Benzododecinium 2913:anti-infectives 2910: 2901: 2891: 2861: 2856: 2855: 2840:Clinical trials 2819: 2768: 2740: 2721: 2717:Mercuric iodide 2672: 2653:Cetylpyridinium 2615: 2581: 2572:Povidone-iodine 2552: 2533: 2494:Hexachlorophene 2487:and derivatives 2479: 2437: 2428:9-Aminoacridine 2408: 2394: 2353: 2350: 2345: 2310: 2281: 2252: 2248: 2246:Further reading 2243: 2242: 2221:(33): 10088–9. 2208: 2207: 2203: 2159: 2158: 2154: 2146: 2115: 2110: 2109: 2102: 2087: 2074: 2073: 2069: 2061: 2060: 2056: 2006: 2005: 2001: 1992: 1990: 1975: 1950: 1949: 1945: 1915: 1914: 1910: 1899: 1884: 1883: 1874: 1838: 1837: 1833: 1819: 1818: 1814: 1776: 1775: 1771: 1725: 1724: 1720: 1690: 1689: 1685: 1647: 1646: 1642: 1604: 1603: 1599: 1549: 1548: 1544: 1494: 1493: 1489: 1453: 1452: 1445: 1435: 1433: 1420: 1419: 1415: 1392: 1391: 1387: 1368: 1353: 1352: 1348: 1329: 1315: 1314: 1307: 1297: 1295: 1287: 1286: 1282: 1263: 1249: 1248: 1231: 1224: 1200: 1199: 1188: 1183: 1151: 1128: 1089: 1005: 998: 995: 994: 993: 991: 978:of the polymer 964: 926: 914: 894:hyperthyroidism 890: 874: 860:(fusion of the 854: 804: 797: 793: 789: 684:wound infection 668: 637:hydrogen iodide 602:kidney problems 571:Povidone-iodine 559: 557: 554:(what is this?) 551: 531: 525: 521: 484: 460: 452: 432: 412: 385: 365: 349: 329: 312: 304: 284: 281: 276: 275: 259: 228: 225: 122: 115: 110:Povidone-iodine 44: 23:Povidone-iodine 17: 12: 11: 5: 4490: 4488: 4480: 4479: 4474: 4469: 4464: 4454: 4453: 4449: 4448: 4425: 4424: 4422: 4421: 4415: 4413: 4409: 4408: 4406: 4405: 4400: 4395: 4390: 4384: 4382: 4376: 4375: 4373: 4372: 4367: 4362: 4357: 4352: 4346: 4344: 4338: 4337: 4335: 4334: 4329: 4324: 4319: 4314: 4309: 4304: 4299: 4294: 4289: 4287:Chlorquinaldol 4284: 4279: 4274: 4260: 4255: 4250: 4248:Amylmetacresol 4245: 4240: 4234: 4232: 4226: 4225: 4219:preparations ( 4215: 4213: 4212: 4205: 4198: 4190: 4181: 4180: 4178: 4177: 4172: 4165: 4160: 4155: 4150: 4145: 4140: 4135: 4129: 4127: 4123: 4122: 4119: 4118: 4116: 4115: 4110: 4104: 4102: 4098: 4097: 4095: 4094: 4092:Amphotericin B 4089: 4084: 4078: 4076: 4070: 4069: 4067: 4066: 4060: 4058: 4052: 4051: 4049: 4048: 4043: 4038: 4033: 4028: 4023: 4018: 4013: 4008: 4003: 3998: 3993: 3988: 3983: 3978: 3972: 3970: 3961: 3955: 3954: 3952: 3951: 3945: 3943: 3937: 3936: 3934: 3933: 3928: 3923: 3917: 3915: 3909: 3908: 3906: 3905: 3900: 3898:Broxyquinoline 3895: 3890: 3888:Chlorquinaldol 3885: 3880: 3874: 3872: 3865: 3864: 3862: 3861: 3855: 3853: 3846: 3845: 3843: 3842: 3837: 3832: 3827: 3822: 3817: 3812: 3807: 3801: 3799: 3793: 3792: 3775: 3773: 3772: 3765: 3758: 3750: 3741: 3740: 3738: 3737: 3732: 3727: 3722: 3712: 3707: 3702: 3697: 3692: 3687: 3682: 3677: 3672: 3667: 3662: 3657: 3652: 3647: 3642: 3632: 3627: 3622: 3617: 3612: 3607: 3602: 3597: 3592: 3587: 3582: 3577: 3567: 3562: 3556: 3554: 3550: 3549: 3547: 3546: 3541: 3540: 3539: 3537:Spironolactone 3534: 3529: 3524: 3512: 3511: 3510: 3505: 3492: 3490: 3484: 3483: 3481: 3480: 3479: 3478: 3473: 3463: 3462: 3461: 3449: 3448: 3447: 3442: 3440:Spironolactone 3437: 3432: 3427: 3415: 3414: 3413: 3408: 3403: 3398: 3385: 3383: 3377: 3376: 3374: 3373: 3370:hydrocortisone 3360: 3359: 3354: 3349: 3344: 3342:Gamolenic acid 3339: 3333: 3331: 3325: 3324: 3322: 3321: 3316: 3310: 3308: 3306:Skin darkening 3302: 3301: 3299: 3298: 3293: 3288: 3282: 3280: 3274: 3273: 3271: 3270: 3267:hydrocortisone 3258: 3257: 3256: 3251: 3239: 3238: 3237: 3227: 3222: 3220:Salicylic acid 3217: 3212: 3200: 3195: 3194: 3193: 3188: 3183: 3171: 3168:Antihistamines 3164: 3163: 3162: 3157: 3152: 3147: 3142: 3137: 3132: 3127: 3122: 3117: 3107: 3095: 3094: 3093: 3091:Spironolactone 3088: 3083: 3078: 3065: 3063: 3057: 3056: 3050:preparations ( 3048:dermatological 3045: 3043: 3042: 3035: 3028: 3020: 3011: 3010: 3008: 3007: 3001: 2993: 2991: 2987: 2986: 2984: 2983: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2943: 2938: 2933: 2928: 2923: 2917: 2915: 2903: 2902: 2892: 2890: 2889: 2882: 2875: 2867: 2858: 2857: 2854: 2853: 2852: 2851: 2848: 2837: 2831: 2825: 2824: 2821: 2820: 2818: 2817: 2812: 2807: 2802: 2797: 2792: 2787: 2782: 2776: 2774: 2770: 2769: 2767: 2766: 2761: 2756: 2750: 2748: 2742: 2741: 2739: 2738: 2736:Silver nitrate 2732: 2730: 2723: 2722: 2720: 2719: 2714: 2709: 2704: 2699: 2694: 2689: 2683: 2681: 2674: 2673: 2671: 2670: 2665: 2660: 2655: 2650: 2636: 2631: 2625: 2623: 2617: 2616: 2614: 2613: 2608: 2603: 2601:Chlorquinaldol 2598: 2592: 2590: 2583: 2582: 2580: 2579: 2574: 2569: 2563: 2561: 2554: 2553: 2551: 2550: 2544: 2542: 2535: 2534: 2532: 2531: 2526: 2521: 2516: 2511: 2506: 2501: 2496: 2490: 2488: 2481: 2480: 2478: 2477: 2472: 2467: 2462: 2457: 2451: 2449: 2439: 2438: 2436: 2435: 2430: 2425: 2419: 2417: 2410: 2409: 2395: 2393: 2392: 2385: 2378: 2370: 2364: 2363: 2349: 2348:External links 2346: 2344: 2343: 2308: 2279: 2249: 2247: 2244: 2241: 2240: 2201: 2152: 2149:on 2010-06-21. 2100: 2085: 2067: 2054: 1999: 1973: 1943: 1908: 1897: 1872: 1851:(3): 297–304. 1831: 1812: 1769: 1718: 1683: 1640: 1597: 1542: 1487: 1443: 1413: 1385: 1366: 1346: 1327: 1305: 1280: 1261: 1229: 1222: 1185: 1184: 1182: 1179: 1178: 1177: 1172: 1170:Lugol's iodine 1167: 1162: 1157: 1150: 1147: 1127: 1124: 1088: 1085: 1077:polyacrylamide 1003: 996: 963: 960: 946:mercury iodide 925: 922: 913: 910: 889: 886: 873: 870: 856:It is used in 853: 850: 845:Herpes simplex 803: 800: 795: 791: 787: 667: 664: 645:microorganisms 566: 565: 548: 547: 544: 538: 537: 527: 523: 519: 516: 510: 509: 505: 504: 494: 486: 485: 483: 482: 469: 467: 454: 453: 451: 450: 442: 440: 434: 433: 431: 430: 422: 420: 414: 413: 411: 410: 403: 395: 393: 387: 386: 384: 383: 375: 373: 367: 366: 364: 363: 359: 357: 351: 350: 348: 347: 339: 337: 331: 330: 328: 327: 319: 317: 306: 305: 303: 302: 294: 292: 286: 285: 283: 282: 279: 271: 270: 269: 266: 265: 261: 260: 258: 257: 243: 241: 235: 234: 230: 229: 227: 226: 224: 223: 211: 199: 187: 175: 163: 150: 137: 135: 129: 128: 125: 123:administration 117: 116: 114: 113: 95: 93: 87: 86: 79: 69: 68: 65: 61: 60: 57: 51: 50: 46: 45: 34: 15: 13: 10: 9: 6: 4: 3: 2: 4489: 4478: 4475: 4473: 4470: 4468: 4467:Disinfectants 4465: 4463: 4460: 4459: 4457: 4447: 4437: 4433: 4420: 4417: 4416: 4414: 4410: 4404: 4401: 4399: 4396: 4394: 4391: 4389: 4386: 4385: 4383: 4381: 4377: 4371: 4368: 4366: 4363: 4361: 4358: 4356: 4353: 4351: 4348: 4347: 4345: 4343: 4339: 4333: 4330: 4328: 4325: 4323: 4320: 4318: 4315: 4313: 4310: 4308: 4305: 4303: 4300: 4298: 4295: 4293: 4290: 4288: 4285: 4283: 4282:Chlorhexidine 4280: 4278: 4275: 4272: 4268: 4264: 4261: 4259: 4256: 4254: 4251: 4249: 4246: 4244: 4241: 4239: 4236: 4235: 4233: 4231: 4227: 4222: 4218: 4211: 4206: 4204: 4199: 4197: 4192: 4191: 4188: 4176: 4175:Copper usnate 4173: 4171: 4170: 4166: 4164: 4161: 4159: 4156: 4154: 4151: 4149: 4146: 4144: 4141: 4139: 4136: 4134: 4131: 4130: 4128: 4124: 4114: 4111: 4109: 4106: 4105: 4103: 4099: 4093: 4090: 4088: 4085: 4083: 4080: 4079: 4077: 4075: 4071: 4065: 4062: 4061: 4059: 4057: 4053: 4047: 4044: 4042: 4039: 4037: 4034: 4032: 4029: 4027: 4026:Propenidazole 4024: 4022: 4019: 4017: 4016:Fenticonazole 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3976:Metronidazole 3974: 3973: 3971: 3969: 3965: 3962: 3960: 3956: 3950: 3949:Sulfatolamide 3947: 3946: 3944: 3942: 3938: 3932: 3931:Ascorbic acid 3929: 3927: 3924: 3922: 3919: 3918: 3916: 3914: 3913:Organic acids 3910: 3904: 3901: 3899: 3896: 3894: 3891: 3889: 3886: 3884: 3881: 3879: 3876: 3875: 3873: 3870: 3866: 3860: 3857: 3856: 3854: 3851: 3847: 3841: 3838: 3836: 3833: 3831: 3828: 3826: 3823: 3821: 3818: 3816: 3813: 3811: 3808: 3806: 3803: 3802: 3800: 3798: 3794: 3789: 3785: 3781: 3778: 3777:Gynecological 3771: 3766: 3764: 3759: 3757: 3752: 3751: 3748: 3736: 3733: 3731: 3728: 3726: 3723: 3720: 3716: 3713: 3711: 3708: 3706: 3703: 3701: 3700:Oxymetazoline 3698: 3696: 3693: 3691: 3688: 3686: 3683: 3681: 3678: 3676: 3673: 3671: 3668: 3666: 3663: 3661: 3658: 3656: 3653: 3651: 3648: 3646: 3643: 3640: 3636: 3633: 3631: 3628: 3626: 3623: 3621: 3618: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3586: 3583: 3581: 3578: 3575: 3571: 3568: 3566: 3563: 3561: 3558: 3557: 3555: 3551: 3545: 3542: 3538: 3535: 3533: 3530: 3528: 3525: 3523: 3520: 3519: 3518: 3517: 3516:Antiandrogens 3513: 3509: 3506: 3504: 3501: 3500: 3499: 3498: 3494: 3493: 3491: 3489: 3485: 3477: 3474: 3472: 3469: 3468: 3467: 3464: 3460: 3457: 3456: 3455: 3454: 3450: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3428: 3426: 3423: 3422: 3421: 3420: 3419:Antiandrogens 3416: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3393: 3392: 3391: 3387: 3386: 3384: 3382: 3378: 3371: 3367: 3366: 3362: 3361: 3358: 3355: 3353: 3350: 3348: 3345: 3343: 3340: 3338: 3335: 3334: 3332: 3330: 3326: 3320: 3317: 3315: 3314:Afamelanotide 3312: 3311: 3309: 3307: 3303: 3297: 3294: 3292: 3289: 3287: 3284: 3283: 3281: 3279: 3275: 3268: 3264: 3263: 3259: 3255: 3252: 3250: 3247: 3246: 3245: 3244: 3243:Lithium salts 3240: 3235: 3231: 3228: 3226: 3223: 3221: 3218: 3216: 3213: 3211: 3208: 3207: 3206: 3205: 3201: 3199: 3196: 3192: 3189: 3187: 3184: 3182: 3179: 3178: 3177: 3176: 3172: 3170: 3169: 3165: 3161: 3158: 3156: 3153: 3151: 3148: 3146: 3143: 3141: 3138: 3136: 3133: 3131: 3128: 3126: 3123: 3121: 3118: 3115: 3111: 3108: 3106: 3103: 3102: 3101: 3100: 3096: 3092: 3089: 3087: 3084: 3082: 3079: 3077: 3074: 3073: 3072: 3071: 3070:Antiandrogens 3067: 3066: 3064: 3062: 3058: 3053: 3049: 3041: 3036: 3034: 3029: 3027: 3022: 3021: 3018: 3005: 3002: 2999: 2995: 2994: 2992: 2988: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2942: 2941:Chlorhexidine 2939: 2937: 2934: 2932: 2929: 2927: 2924: 2922: 2919: 2918: 2916: 2914: 2908: 2904: 2899: 2895: 2888: 2883: 2881: 2876: 2874: 2869: 2868: 2865: 2849: 2847: 2844: 2843: 2841: 2838: 2835: 2832: 2830: 2827: 2826: 2822: 2816: 2813: 2811: 2808: 2806: 2803: 2801: 2798: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2777: 2775: 2771: 2765: 2762: 2760: 2757: 2755: 2752: 2751: 2749: 2747: 2743: 2737: 2734: 2733: 2731: 2728: 2724: 2718: 2715: 2713: 2710: 2708: 2705: 2703: 2700: 2698: 2695: 2693: 2690: 2688: 2685: 2684: 2682: 2679: 2675: 2669: 2666: 2664: 2661: 2659: 2656: 2654: 2651: 2648: 2644: 2640: 2637: 2635: 2632: 2630: 2627: 2626: 2624: 2622: 2618: 2612: 2609: 2607: 2604: 2602: 2599: 2597: 2594: 2593: 2591: 2588: 2584: 2578: 2575: 2573: 2570: 2568: 2565: 2564: 2562: 2559: 2555: 2549: 2548:Nitrofurazone 2546: 2545: 2543: 2540: 2536: 2530: 2527: 2525: 2522: 2520: 2519:Chloroxylenol 2517: 2515: 2512: 2510: 2507: 2505: 2502: 2500: 2497: 2495: 2492: 2491: 2489: 2486: 2482: 2476: 2473: 2471: 2468: 2466: 2463: 2461: 2460:Chlorhexidine 2458: 2456: 2453: 2452: 2450: 2448: 2444: 2440: 2434: 2431: 2429: 2426: 2424: 2421: 2420: 2418: 2415: 2411: 2406: 2402: 2401:disinfectants 2398: 2391: 2386: 2384: 2379: 2377: 2372: 2371: 2368: 2360: 2356: 2352: 2351: 2347: 2340: 2336: 2331: 2326: 2322: 2318: 2314: 2309: 2305: 2301: 2297: 2293: 2289: 2285: 2280: 2276: 2272: 2268: 2264: 2260: 2256: 2251: 2250: 2245: 2236: 2232: 2228: 2224: 2220: 2216: 2212: 2205: 2202: 2197: 2193: 2188: 2183: 2179: 2175: 2171: 2167: 2163: 2156: 2153: 2145: 2141: 2137: 2133: 2129: 2125: 2121: 2114: 2107: 2105: 2101: 2096: 2092: 2088: 2082: 2078: 2071: 2068: 2064: 2058: 2055: 2051: 2046: 2042: 2037: 2032: 2027: 2022: 2018: 2014: 2010: 2003: 2000: 1988: 1984: 1980: 1976: 1970: 1966: 1962: 1958: 1954: 1947: 1944: 1939: 1935: 1931: 1927: 1923: 1919: 1912: 1909: 1904: 1900: 1894: 1890: 1889: 1888:Austria-Codex 1881: 1879: 1877: 1873: 1868: 1864: 1859: 1854: 1850: 1846: 1842: 1835: 1832: 1828:(3): 157–160. 1827: 1823: 1816: 1813: 1807: 1802: 1797: 1792: 1788: 1784: 1780: 1773: 1770: 1765: 1761: 1756: 1751: 1746: 1741: 1738:(3): 502–10. 1737: 1733: 1729: 1722: 1719: 1714: 1710: 1706: 1702: 1698: 1694: 1687: 1684: 1679: 1675: 1671: 1667: 1663: 1659: 1655: 1651: 1644: 1641: 1636: 1632: 1628: 1624: 1620: 1616: 1612: 1608: 1601: 1598: 1593: 1589: 1585: 1581: 1577: 1573: 1569: 1565: 1561: 1557: 1553: 1546: 1543: 1538: 1534: 1530: 1526: 1522: 1518: 1514: 1510: 1506: 1502: 1498: 1491: 1488: 1483: 1479: 1474: 1469: 1465: 1461: 1457: 1450: 1448: 1444: 1431: 1427: 1426:www.drugs.com 1423: 1417: 1414: 1408: 1403: 1399: 1395: 1389: 1386: 1381: 1377: 1373: 1369: 1363: 1359: 1358: 1350: 1347: 1342: 1338: 1334: 1330: 1324: 1320: 1319: 1312: 1310: 1306: 1294: 1290: 1284: 1281: 1276: 1272: 1268: 1264: 1258: 1254: 1253: 1246: 1244: 1242: 1240: 1238: 1236: 1234: 1230: 1225: 1219: 1215: 1211: 1207: 1203: 1197: 1195: 1193: 1191: 1187: 1180: 1176: 1173: 1171: 1168: 1166: 1163: 1161: 1158: 1156: 1153: 1152: 1148: 1146: 1143: 1141: 1132: 1125: 1123: 1121: 1117: 1112: 1110: 1106: 1102: 1098: 1094: 1086: 1084: 1082: 1078: 1074: 1070: 1066: 1062: 1057: 1055: 1051: 1047: 1043: 1039: 1035: 1030: 1028: 1024: 1020: 1016: 1012: 1011:ethyl alcohol 1007: 989: 985: 981: 977: 968: 961: 959: 957: 956: 949: 947: 943: 939: 935: 931: 923: 921: 919: 918:sensitization 911: 909: 907: 903: 899: 898:thyroid gland 895: 887: 885: 883: 879: 878:chlorhexidine 871: 869: 867: 863: 859: 851: 849: 847: 846: 841: 837: 833: 829: 828: 823: 822: 817: 813: 809: 801: 799: 784: 782: 775: 774: 767: 764: 760: 756: 752: 748: 747:stasis ulcers 744: 740: 736: 732: 728: 723: 721: 720:wound healing 717: 713: 709: 708:Chlorhexidine 705: 701: 697: 693: 689: 685: 677: 672: 665: 663: 661: 657: 653: 648: 646: 642: 638: 634: 630: 625: 623: 619: 615: 611: 607: 603: 598: 596: 592: 588: 584: 580: 576: 572: 562: 555: 549: 545: 543: 539: 535: 530: 517: 515: 511: 506: 502: 498: 495: 493: 491:ECHA InfoCard 487: 479: 475: 474:DTXSID8035712 471: 470: 468: 459: 455: 448: 447:ChEMBL1201724 444: 443: 441: 439: 435: 428: 424: 423: 421: 419: 415: 408: 404: 401: 397: 396: 394: 392: 388: 381: 377: 376: 374: 372: 368: 361: 360: 358: 356: 352: 345: 341: 340: 338: 336: 332: 325: 321: 320: 318: 311: 307: 300: 296: 295: 293: 291: 287: 278: 274: 267: 262: 255: 245: 244: 242: 240: 236: 231: 220: 215: 212: 208: 203: 200: 196: 191: 188: 184: 179: 176: 172: 167: 164: 160: 155: 152: 151: 147: 142: 139: 138: 136: 134: 130: 126: 124: 118: 111: 106: 97: 96: 94: 92: 88: 84: 80: 78: 74: 70: 66: 62: 58: 56: 52: 49:Clinical data 47: 42: 38: 32: 27: 19: 4419:Flurbiprofen 4331: 4322:Oxyquinoline 4258:Benzethonium 4253:Benzalkonium 4167: 4157: 4153:Furazolidone 4143:Policresulen 4046:Flutrimazole 4031:Butoconazole 4011:Ketoconazole 3981:Clotrimazole 3941:Sulfonamides 3903:Oxyquinoline 3735:Tralokinumab 3719:progesterone 3715:Progestogens 3704: 3685:Metandienone 3670:Lebrikizumab 3615:Delgocitinib 3574:testosterone 3544:Eflornithine 3522:Bicalutamide 3514: 3495: 3476:Ritlecitinib 3465: 3451: 3425:Bicalutamide 3417: 3388: 3363: 3352:Pimecrolimus 3337:Alitretinoin 3319:Melanotan II 3286:Hydroquinone 3260: 3241: 3204:Keratolytics 3202: 3198:Isotretinoin 3186:Pimecrolimus 3173: 3166: 3135:Ketoconazole 3130:Clotrimazole 3097: 3076:Bicalutamide 3068: 2975: 2956:Fusidic acid 2926:Benzalkonium 2629:Benzalkonium 2606:Oxyquinoline 2571: 2514:Triclocarban 2499:Policresulen 2475:Polihexanide 2358: 2320: 2316: 2290:(3): 79–82. 2287: 2283: 2261:(4): 123–4. 2258: 2254: 2218: 2214: 2204: 2169: 2165: 2155: 2144:the original 2123: 2119: 2076: 2070: 2057: 2048: 2019:(1): 40–57. 2016: 2012: 2002: 1991:. 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3296:Monobenzone 3181:Cyclosporin 3099:Antifungals 2836:from market 2707:Nitromersol 2639:Cetrimonium 2596:Dequalinium 2589:derivatives 2541:derivatives 2465:Propamidine 2416:derivatives 2397:Antiseptics 2323:(5): 1209. 1918:Dermatology 1693:Dermatology 1214:10665/44053 1101:bactericide 1071:(PVA), and 1038:cytoplasmic 986:, PVP) and 938:taurolidine 902:radioiodine 858:pleurodesis 852:Pleurodesis 838:(including 763:trichomonal 497:100.110.412 264:Identifiers 64:Other names 55:Trade names 41:cotton swab 4456:Categories 4388:Benzocaine 4360:Gramicidin 4350:Bacitracin 4307:Hexetidine 4302:Hexamidine 4163:Protiofate 4133:Clodantoin 4108:Ciclopirox 3996:Ornidazole 3986:Miconazole 3968:Imidazoles 3883:Clioquinol 3840:Pentamycin 3815:Hachimycin 3805:Candicidin 3730:Tiratricol 3675:Lokivetmab 3665:Ivermectin 3625:Diclofenac 3471:Nepidermin 3357:Tacrolimus 3215:Resorcinol 3191:Tacrolimus 3155:Xenysalate 3140:Miconazole 3125:Climbazole 3105:Bifonazole 2966:Nitrofural 2951:Framycetin 2946:Clioquinol 2795:Monalazone 2712:Thiomersal 2611:Clioquinol 2539:Nitrofuran 2524:Biphenylol 2470:Hexamidine 2443:Biguanides 2172:: 112573. 1993:2022-02-22 1436:11 January 1271:1031488649 1181:References 751:gynecology 583:antiseptic 542:Molar mass 427:CHEBI:8347 380:85H0HZU99M 355:ChemSpider 299:25655-41-8 290:CAS Number 273:IUPAC name 4403:Lidocaine 4398:Dyclonine 4148:Nifuratel 4087:Natamycin 4056:Triazoles 3991:Econazole 3869:Quinoline 3859:Acetarsol 3852:compounds 3639:estradiol 3635:Estrogens 3630:Dupilumab 3570:Androgens 3532:Flutamide 3459:Minoxidil 3435:Flutamide 3347:Oxaceprol 3114:cetrimide 3086:Flutamide 3000:dressings 2981:Triclosan 2909:dressings 2846:Phase III 2834:Withdrawn 2729:compounds 2702:Merbromin 2678:Mercurial 2658:Cetrimide 2587:Quinoline 2529:Fenticlor 2509:Triclosan 2433:Euflavine 2196:0014-3057 2095:318418088 1983:225472250 1635:210193248 1576:1660-5527 1537:210950872 1521:1432-2323 1337:899175361 1293:drugs.com 1105:complexed 1061:hydrogels 988:triiodide 962:Structure 755:vaginitis 696:abrasions 585:used for 121:Routes of 77:Drugs.com 4446:Medicine 4365:Neomycin 4271:chloride 4243:Ambazone 4082:Nystatin 4074:Polyenes 3600:Collagen 3590:Caffeine 3291:Mequinol 3210:Coal tar 3006:bandages 2998:paraffin 2961:Iodoform 2907:Ointment 2790:Halazone 2746:Alcohols 2680:products 2647:chloride 2560:products 2447:amidines 2414:Acridine 2339:22219431 2304:70528331 2275:71797553 2235:17663555 2045:33362938 1987:Archived 1903:Archived 1867:22561614 1764:19153076 1678:46968733 1670:29880433 1627:31928890 1584:29262416 1529:31996985 1482:32773627 1430:Archived 1396:(2021). 1380:Archived 1376:62301847 1341:Archived 1275:Archived 1160:Iodophor 1149:See also 1126:Research 1116:in vitro 1109:iodophor 1050:protozoa 1042:bacteria 1023:glycerol 980:povidone 955:Guaiacum 812:solution 808:buffered 759:candidal 700:blisters 660:Betadine 633:povidone 614:pregnant 581:, is an 561:(verify) 546:variable 335:DrugBank 214:QG51AD01 133:ATC code 105:DailyMed 39:using a 37:abrasion 4393:Cocaine 4267:bromide 4138:Inosine 3850:Arsenic 3717:(e.g., 3637:(e.g., 3572:(e.g., 3368:(e.g., 3265:(e.g., 2643:bromide 2174:Bibcode 2128:Bibcode 2036:7749746 1938:9403263 1858:3361864 1806:6457593 1755:2640157 1713:9403248 1592:3601026 1165:Inadine 1087:History 1073:gelatin 1067:(CMC), 1054:viruses 958:resin. 942:mercury 836:viruses 622:lithium 591:surgery 514:Formula 344:DB06812 310:PubChem 216: ( 204: ( 202:S01AX18 192: ( 190:R02AA15 180: ( 178:G01AX11 168: ( 166:D11AC06 156: ( 154:D09AA09 149:) 143: ( 141:D08AG02 127:Topical 107::  4472:Iodine 4432:Portal 4327:Phenol 4217:Throat 3553:Others 3466:Others 3225:Sulfur 3046:Other 2829:WHO-EM 2727:Silver 2558:Iodine 2504:Phenol 2485:Phenol 2337:  2302:  2273:  2233:  2194:  2120:Carbon 2093:  2083:  2043:  2033:  1981:  1971:  1936:  1895:  1865:  1855:  1803:  1762:  1752:  1711:  1676:  1668:  1633:  1625:  1590:  1582:  1574:  1535:  1527:  1519:  1480:  1374:  1364:  1335:  1325:  1298:11 May 1269:  1259:  1220:  1093:iodine 1052:, and 1034:lipids 1021:, and 934:silver 862:pleura 810:PVP-I 778:a.k.a. 731:ulcers 727:wounds 641:iodine 608:, and 595:wounds 438:ChEMBL 407:C08043 400:D00863 324:410087 252: 103:  4412:Other 4126:Other 4101:Other 2996:Soft 2990:Other 2911:with 2805:Eosin 2773:Other 2300:S2CID 2271:S2CID 2147:(PDF) 2116:(PDF) 1979:S2CID 1674:S2CID 1631:S2CID 1588:S2CID 1533:S2CID 1081:wound 1046:fungi 832:fungi 824:, or 749:; in 739:burns 692:burns 676:Gauze 575:PVP-I 418:ChEBI 3782:and 3230:Urea 3004:Zinc 2445:and 2399:and 2335:PMID 2231:PMID 2192:ISSN 2091:OCLC 2081:ISBN 2041:PMID 1969:ISBN 1934:PMID 1893:ISBN 1863:PMID 1760:PMID 1709:PMID 1666:PMID 1623:PMID 1580:PMID 1572:ISSN 1525:PMID 1517:ISSN 1478:PMID 1438:2017 1372:OCLC 1362:ISBN 1333:OCLC 1323:ISBN 1300:2024 1267:OCLC 1257:ISBN 1218:ISBN 916:The 880:and 866:talc 842:and 834:and 802:Eyes 753:for 745:and 737:and 735:cuts 714:and 698:and 688:cuts 391:KEGG 371:UNII 362:none 73:AHFS 4221:R02 3788:G01 3052:D11 2898:D09 2405:D08 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Index


abrasion
cotton swab
Trade names
AHFS
Drugs.com
Consumer Drug Information
License data
DailyMed
Povidone-iodine
Routes of
administration

ATC code
D08AG02
WHO
D09AA09
WHO
D11AC06
WHO
G01AX11
WHO
R02AA15
WHO
S01AX18
WHO
QG51AD01
WHO
Legal status
OTC
IUPAC name
CAS Number

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