191:
57:
95:. This controversy also depends on the exact CIS in question (i.e. cervical, skin, breast). Some authors do not classify them as cancer, however, recognizing that they can potentially become cancer. Others classify certain types as a non-invasive form of cancer. The term "
263:(BAC) of the lung is the only form of CIS that can kill directly because, in rare cases (the "pneumonic form"), it expands greatly and fills the lungs, preventing breathing and causing other dire effects on the host. Thus, the pneumonic form of BAC is a true
118:. Rather, the lesion is flat (in the skin, cervix, etc.) or follows the existing architecture of the organ (in the breast, lung, etc.). Exceptions include CIS of the colon (polyps), the bladder (preinvasive papillary cancer), or the breast (
135:
Many forms of CIS have a high probability of progression into cancer, and therefore removal may be recommended; however, progression of CIS is known to be highly variable and not all CIS becomes invasive cancer.
198:) in the uterine cervix: The abnormal epithelium is extending into a mucous gland to the left of center. This disease can progress to invasive cancer (squamous cell carcinoma) of the cervix.
603:
114:, is the accumulation of dysplastic epidermal cells within the epidermis only, that has failed to penetrate into the deeper dermis. For this reason, CIS will usually not form a
319:
is removed by excision (cutting it out) or by burning with a laser. Bowen's disease of the skin is removed by excision. Other forms require major surgery, the best known being
254:
505:
437:
358:
296:
unless it progresses into cancer. Therefore, its removal eliminates the risk of subsequent progression into a life-threatening condition.
555:
316:
204:
410:
664:
516:
979:
260:
502:
1010:
804:
126:
839:
797:
614:
320:
222:
119:
181:, has the potential to invade and spread to surrounding tissues and structures, and may eventually be lethal.
1051:
932:
896:
834:
937:
891:
96:
267:
entity, but is not "invasive" in the classical sense. For this reason, it is considered a form of CIS by
989:
970:
170:. Dysplasia can be low-grade or high-grade. High-grade dysplasia may also be referred to as carcinoma
942:
787:
777:
657:
829:
761:
312:
533:
1056:
922:
235:
140:
231:
111:
1025:
1015:
927:
484:
433:
427:
406:
354:
348:
64:
400:
914:
792:
474:
466:
244:
374:
1030:
1005:
650:
642:
520:
509:
212:
159:
These terms are related since they represent the steps of the progression toward cancer:
952:
910:
608:
479:
454:
304:
148:
1045:
756:
513:
470:
190:
56:
697:
324:
248:
619:
1020:
960:
819:
782:
705:
402:
International statistical classification of diseases and related health problems
268:
207:(SIL), previously called cervical intraepithelial neoplasia (CIN), is a form of
279:, and inclusion of this form of cancer among the types of CIS is controversial.
965:
814:
751:
715:
293:
272:
984:
870:
855:
736:
720:
625:
455:"Ductal carcinoma in situ: terminology, classification, and natural history"
308:
264:
208:
163:
488:
974:
865:
824:
809:
682:
674:
88:
69:
17:
595:
405:(10. rev., 2. ed.). Geneva: World Health Organization. p. 38.
875:
860:
300:
276:
746:
678:
178:
167:
92:
429:
Common surgical diseases an algorithmic approach to problem solving
247:
often contain areas of CIS that will almost always transform into
189:
115:
630:
292:
is, by definition, a localized phenomenon, with no potential for
91:, there is disagreement over whether CIS should be classified as
710:
646:
166:
is the earliest form of precancerous lesion recognizable in a
106:" (from Latin for "in its place"). For example, carcinoma
87:) is a group of abnormal cells. While they are a form of
512:
in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds)
102:
These abnormal cells grow in their normal place, thus "
585:
459:
Journal of the
National Cancer Institute. Monographs
228:
of the breast is the most common precancer in women.
998:
951:
909:
884:
848:
770:
729:
696:
689:
589:
63:
43:
35:
219:may be used interchangeably with high-grade SIL.
514:Cancer Management: A Multidisciplinary Approach
255:High-grade prostatic intraepithelial neoplasia
658:
426:Myers JA, Millikan KW, Saclarides TJ (2008).
8:
342:
340:
693:
665:
651:
643:
586:
177:Invasive carcinoma, usually simply called
55:
32:
478:
432:(2nd rev. ed.). New York: Springer.
501:Ridge JA, Glisson BS, Lango MN, et al.
336:
27:Pre-cancerous abnormal growth of tissue
257:is equivalent to CIS of the prostate.
7:
350:Oncology: An Evidence-Based Approach
321:intraductal carcinoma of the breast
399:World Health Organization (2004).
25:
556:"Understanding Cervical Changes"
311:, without conventional surgical
194:High-grade dysplasia (carcinoma
317:Dysplasia of the uterine cervix
205:squamous intraepithelial lesion
565:. National Institute of Health
1:
980:Clonally transmissible cancer
471:10.1093/jncimonographs/lgq035
261:Bronchioloalveolar carcinoma
536:. National Cancer Institute
534:"Cancer Staging Fact Sheet"
1073:
1011:Index of oncology articles
307:) can be removed using an
143:classification, carcinoma
563:National Cancer Institute
379:World Health Organization
353:. Springer. p. 162.
299:Some forms of CIS (e.g.,
110:of the skin, also called
54:
147:is reported as TisN0M0 (
933:Prostate cancer staging
897:Paraneoplastic syndrome
971:Tumor suppressor genes
938:Gleason grading system
892:Precancerous condition
503:"Head and Neck Tumors"
305:tumours of the bladder
199:
99:" has also been used.
990:Carcinogenic bacteria
730:Malignant progression
215:. The term carcinoma
211:that can progress to
193:
943:Dukes classification
762:Sentinel lymph node
323:(also treated with
810:Respiratory system
519:2013-10-04 at the
508:2009-07-20 at the
453:Allred DC (2010).
251:if left untreated.
236:squamous carcinoma
200:
127:lobular carcinoma
1039:
1038:
1026:Cancer and nausea
905:
904:
742:Carcinoma in situ
640:
639:
439:978-0-387-75246-4
360:978-0-387-31056-5
223:Ductal carcinoma
120:ductal carcinoma
75:
74:
30:Medical condition
16:(Redirected from
1064:
840:Endocrine system
805:Digestive system
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347:Chang A (2007).
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521:Wayback Machine
510:Wayback Machine
500:
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465:(41): 134–138.
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232:Bowen's disease
213:cervical cancer
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112:Bowen's disease
31:
28:
23:
22:
15:
12:
11:
5:
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1052:Histopathology
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953:Carcinogenesis
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835:Nervous system
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798:nasopharyngeal
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590:Classification
583:
582:External links
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523:. 11 ed. 2008.
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788:oropharyngeal
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778:Head and neck
776:
775:
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769:
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757:Primary tumor
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698:Benign tumors
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412:9789241546492
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380:
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375:"II Neoplams"
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303:and polypoid
302:
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39:
34:
19:
741:
673:Overview of
624:
613:
602:
567:. Retrieved
562:
550:
538:. Retrieved
528:
497:
462:
458:
448:
428:
421:
401:
394:
382:. Retrieved
378:
369:
349:
325:radiotherapy
301:colon polyps
298:
289:
287:
269:pathologists
249:colon cancer
245:Colon polyps
241:of the skin.
238:
224:
216:
195:
171:
158:
144:
138:
134:
128:
121:
107:
103:
101:
84:
79:
77:
76:
47:
37:
1021:Cancer pain
961:Cancer cell
706:Hyperplasia
273:oncologists
155:Terminology
44:Other names
1046:Categories
966:Carcinogen
830:Urogenital
771:Topography
752:Metastasis
716:Pseudocyst
690:Conditions
331:References
294:metastasis
288:Carcinoma
97:pre-cancer
78:Carcinoma
36:Carcinoma
1057:Carcinoma
985:Oncovirus
975:oncogenes
928:Ann Arbor
871:Papilloma
856:Carcinoma
849:Histology
793:laryngeal
737:Dysplasia
721:Hamartoma
626:SNOMED CT
313:resection
309:endoscope
284:Treatment
265:malignant
209:dysplasia
203:Cervical
164:Dysplasia
65:Specialty
18:Precancer
1006:Research
866:Blastoma
683:oncology
631:68956006
540:June 24,
517:Archived
506:Archived
489:20956817
277:surgeons
186:Examples
89:neoplasm
70:Oncology
50:neoplasm
1016:History
915:grading
911:Staging
876:Adenoma
861:Sarcoma
620:D002278
609:M8010/2
569:17 June
480:5161057
384:19 June
290:in situ
239:in situ
225:in situ
217:in situ
196:in situ
172:in situ
145:in situ
139:In the
129:in situ
122:in situ
108:in situ
104:in situ
80:in situ
48:in situ
38:in situ
747:Cancer
679:cancer
675:tumors
487:
477:
436:
409:
357:
179:cancer
168:biopsy
93:cancer
999:Misc.
885:Other
825:Blood
604:ICD-O
559:(PDF)
234:is a
149:stage
116:tumor
1031:Diet
820:Skin
815:Bone
783:oral
711:Cyst
681:and
615:MeSH
571:2014
542:2014
485:PMID
463:2010
434:ISBN
407:ISBN
386:2014
355:ISBN
151:0).
923:TNM
475:PMC
467:doi
327:).
275:or
141:TNM
132:).
125:or
85:CIS
1048::
677:,
629::
618::
607::
561:.
483:.
473:.
461:.
457:.
377:.
339:^
315:.
973:/
913:/
666:e
659:t
652:v
596:D
573:.
544:.
491:.
469::
442:.
415:.
388:.
363:.
174:.
83:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
