302:
279:
176:
201:
553:
308:
207:
29:
1163:(CNS). The encoded protein functions in myelination. This protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with this gene cause X-linked Pelizaeus–Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for this gene.
2771:
55:
1879:
Kronquist KE, Crandall BF, Macklin WB, Campagnoni AT (1988). "Expression of myelin proteins in the developing human spinal cord: cloning and sequencing of human proteolipid protein cDNA".
1731:
Weimbs T, Dick T, Stoffel W, Boltshauser E (1991). "A point mutation at the X-chromosomal proteolipid protein locus in
Pelizaeus-Merzbacher disease leads to disruption of myelinogenesis".
2257:
315:
214:
1702:
Pratt VM, Trofatter JA, Schinzel A, et al. (1991). "A new mutation in the proteolipid protein (PLP) gene in a German family with
Pelizaeus-Merzbacher disease".
2691:
2751:
1167:
2094:
Mattei MG, Alliel PM, Dautigny A, et al. (1986). "The gene encoding for the major brain proteolipid (PLP) maps on the q-22 band of the human X chromosome".
2250:
2184:
Kahan I, Moscarello MA (1986). "The intramembranous domains of lipophilin in phosphatidylcholine vesicles are similar to those in the myelin membrane".
806:
787:
2487:
2482:
137:
2061:"Pelizaeus-Merzbacher disease: an X-linked neurologic disorder of myelin metabolism with a novel mutation in the gene encoding proteolipid protein"
2235:
2812:
1669:"Pelizaeus-Merzbacher disease: detection of mutations Thr181----Pro and Leu223----Pro in the proteolipid protein gene, and prenatal diagnosis"
2243:
1275:
1257:
2831:
1152:. It is a 4 transmembrane domain protein which is proposed to bind other copies of itself on the extracellular side of the membrane. In a
52:
2454:
1074:
301:
1081:
1149:
278:
1293:
1455:
Woodward K, Malcolm S (1999). "Proteolipid protein gene: Pelizaeus-Merzbacher disease in humans and neurodegeneration in mice".
1799:"Pelizaeus-Merzbacher disease: a valine to phenylalanine point mutation in a putative extracellular loop of myelin proteolipid"
1595:
Inoue K (2005). "PLP1-related inherited dysmyelinating disorders: Pelizaeus-Merzbacher disease and spastic paraplegia type 2".
1244:
1223:
2459:
1240:
1156:
sheath, as the layers of myelin wraps come together, PLP will bind itself and tightly hold the cellular membranes together.
200:
175:
1219:
1399:
Edwards, A M; Ross N W; Ulmer J B; Braun P E (Jan 1989). "Interaction of myelin basic protein and proteolipid protein".
117:
1556:"Pelizaeus-Merzbacher disease and spastic paraplegia type 2: two faces of myelin loss from mutations in the same gene"
1179:
314:
213:
2805:
2442:
1137:
1348:
Wood, D D; Vella G J; Moscarello M A (Oct 1984). "Interaction between human myelin basic protein and lipophilin".
1850:
Simons R, Alon N, Riordan JR (1987). "Human myelin DM-20 proteolipid protein deletion defined by cDNA sequence".
307:
206:
2224:
1916:
Edwards AM, Ross NW, Ulmer JB, Braun PE (1989). "Interaction of myelin basic protein and proteolipid protein".
851:
125:
1294:"Entrez Gene: PLP1 proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)"
2723:
1159:
This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the
832:
2836:
1160:
2798:
2274:
2230:
2474:
2430:
2324:
2144:
2019:
1966:
1810:
1634:"Molecular diagnostics for myelin proteolipid protein gene mutations in Pelizaeus-Merzbacher disease"
1183:
189:
104:
2464:
1057:
1047:
1043:
1039:
1031:
1012:
1008:
978:
974:
964:
960:
956:
952:
933:
929:
1760:
Popot JL, Pham Dinh D, Dautigny A (1991). "Major Myelin proteolipid: the 4-alpha-helix topology".
2220:
2119:
1941:
1904:
1785:
1620:
1583:
1432:
1381:
149:
1035:
1016:
1004:
948:
925:
921:
2201:
2172:
2111:
2082:
2047:
1994:
1933:
1896:
1867:
1838:
1777:
1748:
1719:
1690:
1655:
1612:
1575:
1542:
1507:
1472:
1424:
1416:
1373:
1365:
1330:
97:
45:
2782:
2670:
2665:
2610:
2600:
2595:
2585:
2580:
2575:
2555:
1955:"Mutation of the proteolipid protein gene PLP in a human X chromosome-linked myelin disorder"
2696:
2525:
2505:
2412:
2407:
2402:
2397:
2392:
2387:
2377:
2367:
2362:
2352:
2347:
2270:
2193:
2162:
2152:
2103:
2072:
2037:
2027:
1984:
1974:
1925:
1888:
1859:
1828:
1818:
1769:
1740:
1711:
1680:
1645:
1604:
1567:
1532:
1497:
1464:
1408:
1357:
1320:
552:
394:
325:
269:
224:
2382:
2357:
2133:"Individual exons encode the integral membrane domains of human myelin proteolipid protein"
2309:
2304:
369:
145:
2148:
2023:
1970:
1814:
2077:
2060:
1685:
1668:
1650:
1633:
2167:
2132:
2042:
2008:"Pelizaeus-Merzbacher disease: tight linkage to proteolipid protein gene exon variant"
2007:
1989:
1954:
1468:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
640:
635:
630:
625:
609:
604:
599:
594:
28:
2825:
2197:
1863:
1833:
1798:
1325:
1308:
581:
2123:
1945:
1789:
1624:
1587:
1436:
2282:
1908:
1385:
387:
166:
1744:
129:
1571:
153:
2635:
2497:
1502:
1485:
1280:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1262:
National Center for
Biotechnology Information, U.S. National Library of Medicine
470:
2718:
2701:
2299:
1608:
286:
183:
133:
1420:
1369:
2728:
2157:
2032:
1979:
1823:
1715:
1521:"The proteolipid protein gene and myelin disorders in man and animal models"
751:
530:
408:
353:
340:
252:
239:
141:
1616:
1579:
1546:
1511:
1476:
1334:
2205:
2176:
2115:
2086:
2051:
1998:
1937:
1929:
1900:
1892:
1871:
1842:
1781:
1752:
1723:
1694:
1659:
1537:
1520:
1428:
1412:
1377:
1121:
1116:
2686:
2291:
1141:
1105:
896:
877:
1309:"Novel MITF targets identified using a two-step DNA microarray strategy"
2778:
2660:
2655:
2615:
2605:
2590:
2570:
2565:
2560:
2550:
2266:
2107:
1773:
1361:
863:
818:
2770:
74:
2545:
2540:
2535:
2530:
2520:
2515:
2510:
2422:
2278:
1153:
1089:
773:
1555:
108:, GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2, proteolipid protein 1
2711:
2706:
2620:
2372:
2342:
2337:
736:
732:
2738:
2733:
2650:
2640:
2630:
2625:
2435:
2332:
2314:
1195:
121:
2239:
1797:
Pham-Dinh D, Popot JL, Boespflug-Tanguy O, et al. (1991).
561:
2645:
1166:
In melanocytic cells PLP1 gene expression may be regulated by
1486:"The molecular pathogenesis of Pelizaeus-Merzbacher disease"
1667:
Strautnieks S, Rutland P, Winter RM, et al. (1992).
377:
2786:
2006:
Trofatter JA, Dlouhy SR, DeMyer W, et al. (1990).
1307:
Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008).
2231:
GeneReview/NCBI/NIH/UW entry on PLP1-Related
Disorders
2131:
Diehl HJ, Schaich M, Budzinski RM, Stoffel W (1987).
542:
1953:
Hudson LD, Puckett C, Berndt J, et al. (1989).
1632:
Doll R, Natowicz MR, Schiffmann R, Smith FI (1992).
2679:
2496:
2473:
2421:
2323:
2290:
1030:
997:
947:
914:
1236:
1234:
1232:
1215:
1213:
1211:
1519:Yool DA, Edgar JM, Montague P, Malcolm S (2000).
324:
223:
2059:Gencic S, Abuelo D, Ambler M, Hudson LD (1989).
2692:LDL-receptor-related protein-associated protein
1241:GRCm38: Ensembl release 89: ENSMUSG00000031425
2806:
2251:
1484:Garbern J, Cambi F, Shy M, Kamholz J (1999).
8:
1220:GRCh38: Ensembl release 89: ENSG00000123560
2813:
2799:
2258:
2244:
2236:
1027:
944:
747:
702:long-chain fatty acid biosynthetic process
577:
365:
264:
161:
63:
2488:Pulmonary surfactant-associated protein C
2483:Pulmonary surfactant-associated protein B
2223:at the U.S. National Library of Medicine
2166:
2156:
2076:
2041:
2031:
1988:
1978:
1832:
1822:
1684:
1649:
1536:
1501:
1324:
1178:Proteolipid protein 1 has been shown to
1207:
600:structural constituent of myelin sheath
682:positive regulation of gene expression
18:
2752:other cell membrane protein disorders
329:
290:
285:
228:
187:
182:
7:
2767:
2765:
2455:Myelin oligodendrocyte glycoprotein
662:integrin-mediated signaling pathway
2785:. You can help Knowledge (XXG) by
994:
911:
887:
868:
842:
823:
797:
778:
712:central nervous system myelination
547:
465:
403:
382:
14:
16:Type of myelin-associated protein
2769:
1326:10.1111/j.1755-148X.2008.00505.x
551:
427:inferior ganglion of vagus nerve
313:
306:
300:
277:
212:
205:
199:
174:
27:
2724:Phospholipid transfer proteins
2460:Myelin-associated glycoprotein
1356:(10). UNITED STATES: 1523–31.
717:chemical synaptic transmission
626:integral component of membrane
562:More reference expression data
531:More reference expression data
1:
1852:Biochem. Biophys. Res. Commun
1745:10.1515/bchm3.1990.371.2.1175
1469:10.1016/S0168-9525(99)01716-3
722:neuron projection development
298:
197:
2198:10.1016/0005-2736(86)90487-6
2137:Proc. Natl. Acad. Sci. U.S.A
2012:Proc. Natl. Acad. Sci. U.S.A
1959:Proc. Natl. Acad. Sci. U.S.A
1864:10.1016/0006-291X(87)90580-8
1803:Proc. Natl. Acad. Sci. U.S.A
1572:10.1177/08830738030180090801
1407:(1). UNITED STATES: 97–102.
1150:Pelizaeus–Merzbacher disease
707:substantia nigra development
605:structural molecule activity
2832:Genes on human chromosome X
1503:10.1001/archneur.56.10.1210
431:superior vestibular nucleus
2853:
2764:
2443:Myelin proteolipid protein
1138:myelin proteolipid protein
692:glial cell differentiation
489:lateral geniculate nucleus
2747:
1609:10.1007/s10048-004-0207-y
1313:Pigment Cell Melanoma Res
1276:"Mouse PubMed Reference:"
1258:"Human PubMed Reference:"
1120:
1115:
1111:
1104:
1088:
1082:Chr X: 135.72 – 135.74 Mb
1075:Chr X: 103.77 – 103.79 Mb
1069:
1054:
1001:
990:
971:
918:
907:
894:
890:
875:
871:
862:
849:
845:
830:
826:
817:
804:
800:
785:
781:
772:
757:
750:
746:
730:
610:identical protein binding
580:
576:
559:
550:
541:
528:
513:medial geniculate nucleus
509:medial vestibular nucleus
477:
468:
415:
406:
376:
368:
364:
347:
334:
297:
276:
267:
263:
246:
233:
196:
173:
164:
160:
115:
112:
102:
95:
90:
71:
66:
49:
44:
39:
35:
26:
21:
2225:Medical Subject Headings
1733:Biol. Chem. Hoppe-Seyler
505:dorsal tegmental nucleus
2158:10.1073/pnas.83.24.9807
2033:10.1073/pnas.86.23.9427
1980:10.1073/pnas.86.20.8128
1824:10.1073/pnas.88.17.7562
1716:10.1002/ajmg.1320380129
2781:-related article is a
2186:Biochim. Biophys. Acta
1161:central nervous system
493:ventral tegmental area
485:deep cerebellar nuclei
443:ventral tegmental area
2275:Cell surface receptor
1930:10.1002/jnr.490220113
1893:10.1002/jnr.490180303
1413:10.1002/jnr.490220113
1134:Proteolipid protein 1
687:inflammatory response
667:astrocyte development
2475:Pulmonary surfactant
2431:Myelin basic protein
2325:Membrane-spanning 4A
1184:Myelin basic protein
1148:are associated with
1136:(PLP1) is a form of
501:lateral hypothalamus
419:middle frontal gyrus
292:X chromosome (mouse)
190:X chromosome (human)
67:List of PDB id codes
40:Available structures
2465:Myelin protein zero
2221:PLP1+protein,+human
2149:1986PNAS...83.9807D
2024:1989PNAS...86.9427T
1971:1989PNAS...86.8128H
1815:1991PNAS...88.7562P
1538:10.1093/hmg/9.6.987
439:subthalamic nucleus
331:X F1|X 59.1 cM
2108:10.1007/BF00290964
1774:10.1007/BF01868534
1554:Hudson LD (2003).
1362:10.1007/BF00964678
852:ENSMUSG00000031425
650:Biological process
619:Cellular component
588:Molecular function
2794:
2793:
2759:
2758:
2271:membrane proteins
2065:Am. J. Hum. Genet
1704:Am. J. Med. Genet
1673:Am. J. Hum. Genet
1638:Am. J. Hum. Genet
1131:
1130:
1127:
1126:
1100:
1099:
1065:
1064:
1024:
1023:
986:
985:
941:
940:
903:
902:
884:
883:
858:
857:
839:
838:
813:
812:
794:
793:
742:
741:
657:axon ensheathment
572:
571:
568:
567:
537:
536:
524:
523:
517:nucleus accumbens
462:
461:
360:
359:
259:
258:
86:
85:
82:
81:
50:Ortholog search:
2844:
2815:
2808:
2801:
2773:
2766:
2260:
2253:
2246:
2237:
2209:
2180:
2170:
2160:
2127:
2090:
2080:
2055:
2045:
2035:
2002:
1992:
1982:
1949:
1918:J. Neurosci. Res
1912:
1881:J. Neurosci. Res
1875:
1846:
1836:
1826:
1793:
1756:
1727:
1698:
1688:
1663:
1653:
1628:
1591:
1550:
1540:
1515:
1505:
1480:
1441:
1440:
1401:J. Neurosci. Res
1396:
1390:
1389:
1345:
1339:
1338:
1328:
1304:
1298:
1297:
1290:
1284:
1283:
1272:
1266:
1265:
1254:
1248:
1238:
1227:
1217:
1113:
1112:
1084:
1077:
1060:
1028:
1019:
995:
991:RefSeq (protein)
981:
945:
936:
912:
888:
869:
843:
824:
798:
779:
748:
677:axon development
578:
564:
555:
548:
533:
473:
471:Top expressed in
466:
411:
409:Top expressed in
404:
383:
366:
356:
343:
332:
317:
310:
304:
293:
281:
265:
255:
242:
231:
216:
209:
203:
192:
178:
162:
156:
154:PLP1 - orthologs
107:
100:
77:
64:
58:
37:
36:
31:
19:
2852:
2851:
2847:
2846:
2845:
2843:
2842:
2841:
2822:
2821:
2820:
2819:
2762:
2760:
2755:
2743:
2697:Neurofibromin 2
2680:Other/ungrouped
2675:
2492:
2469:
2417:
2319:
2286:
2264:
2217:
2212:
2183:
2143:(24): 9807–11.
2130:
2093:
2058:
2018:(23): 9427–30.
2005:
1965:(20): 8128–31.
1952:
1915:
1878:
1849:
1796:
1759:
1739:(12): 1175–83.
1730:
1701:
1666:
1631:
1594:
1560:J. Child Neurol
1553:
1525:Hum. Mol. Genet
1518:
1483:
1454:
1450:
1448:Further reading
1445:
1444:
1398:
1397:
1393:
1347:
1346:
1342:
1306:
1305:
1301:
1292:
1291:
1287:
1274:
1273:
1269:
1256:
1255:
1251:
1239:
1230:
1218:
1209:
1204:
1192:
1176:
1122:View/Edit Mouse
1117:View/Edit Human
1080:
1073:
1070:Location (UCSC)
1056:
1050:
1046:
1042:
1038:
1034:
1015:
1011:
1007:
1003:
977:
973:
967:
963:
959:
955:
951:
932:
928:
924:
920:
833:ENSG00000123560
726:
697:cell maturation
645:
636:plasma membrane
614:
595:protein binding
560:
529:
520:
515:
511:
507:
503:
499:
495:
491:
487:
483:
481:globus pallidus
469:
458:
455:pars reticulata
453:
449:
445:
441:
437:
433:
429:
425:
423:corpus callosum
421:
407:
351:
338:
330:
320:
319:
318:
311:
291:
268:Gene location (
250:
237:
229:
219:
218:
217:
210:
188:
165:Gene location (
116:
103:
96:
73:
51:
17:
12:
11:
5:
2850:
2848:
2840:
2839:
2834:
2824:
2823:
2818:
2817:
2810:
2803:
2795:
2792:
2791:
2774:
2757:
2756:
2748:
2745:
2744:
2742:
2741:
2736:
2731:
2726:
2721:
2716:
2715:
2714:
2709:
2699:
2694:
2689:
2683:
2681:
2677:
2676:
2674:
2673:
2668:
2663:
2658:
2653:
2648:
2643:
2638:
2633:
2628:
2623:
2618:
2613:
2608:
2603:
2598:
2593:
2588:
2583:
2578:
2573:
2568:
2563:
2558:
2553:
2548:
2543:
2538:
2533:
2528:
2523:
2518:
2513:
2508:
2502:
2500:
2494:
2493:
2491:
2490:
2485:
2479:
2477:
2471:
2470:
2468:
2467:
2462:
2457:
2452:
2451:
2450:
2440:
2439:
2438:
2427:
2425:
2419:
2418:
2416:
2415:
2410:
2405:
2400:
2395:
2390:
2385:
2380:
2375:
2370:
2365:
2360:
2355:
2350:
2345:
2340:
2335:
2329:
2327:
2321:
2320:
2318:
2317:
2312:
2307:
2302:
2296:
2294:
2288:
2287:
2265:
2263:
2262:
2255:
2248:
2240:
2234:
2233:
2228:
2216:
2215:External links
2213:
2211:
2210:
2181:
2128:
2091:
2056:
2003:
1950:
1913:
1887:(3): 395–401.
1876:
1847:
1809:(17): 7562–6.
1794:
1762:J. Membr. Biol
1757:
1728:
1699:
1664:
1629:
1592:
1551:
1516:
1496:(10): 1210–4.
1481:
1451:
1449:
1446:
1443:
1442:
1391:
1350:Neurochem. Res
1340:
1299:
1285:
1267:
1249:
1228:
1206:
1205:
1203:
1200:
1199:
1198:
1191:
1188:
1175:
1172:
1129:
1128:
1125:
1124:
1119:
1109:
1108:
1102:
1101:
1098:
1097:
1095:
1093:
1086:
1085:
1078:
1071:
1067:
1066:
1063:
1062:
1052:
1051:
1025:
1022:
1021:
999:
998:
992:
988:
987:
984:
983:
969:
968:
942:
939:
938:
916:
915:
909:
905:
904:
901:
900:
892:
891:
885:
882:
881:
873:
872:
866:
860:
859:
856:
855:
847:
846:
840:
837:
836:
828:
827:
821:
815:
814:
811:
810:
802:
801:
795:
792:
791:
783:
782:
776:
770:
769:
764:
759:
755:
754:
744:
743:
740:
739:
728:
727:
725:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
674:
669:
664:
659:
653:
651:
647:
646:
644:
643:
638:
633:
628:
622:
620:
616:
615:
613:
612:
607:
602:
597:
591:
589:
585:
584:
574:
573:
570:
569:
566:
565:
557:
556:
545:
539:
538:
535:
534:
526:
525:
522:
521:
519:
518:
514:
510:
506:
502:
498:
497:pontine nuclei
494:
490:
486:
482:
478:
475:
474:
463:
460:
459:
457:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
416:
413:
412:
400:
399:
391:
380:
374:
373:
370:RNA expression
362:
361:
358:
357:
349:
345:
344:
336:
333:
328:
322:
321:
312:
305:
299:
295:
294:
289:
283:
282:
274:
273:
261:
260:
257:
256:
248:
244:
243:
235:
232:
227:
221:
220:
211:
204:
198:
194:
193:
186:
180:
179:
171:
170:
158:
157:
114:
110:
109:
101:
93:
92:
88:
87:
84:
83:
80:
79:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2849:
2838:
2837:Protein stubs
2835:
2833:
2830:
2829:
2827:
2816:
2811:
2809:
2804:
2802:
2797:
2796:
2790:
2788:
2784:
2780:
2775:
2772:
2768:
2763:
2754:
2753:
2746:
2740:
2737:
2735:
2732:
2730:
2727:
2725:
2722:
2720:
2717:
2713:
2710:
2708:
2705:
2704:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2685:
2684:
2682:
2678:
2672:
2669:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2647:
2644:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2622:
2619:
2617:
2614:
2612:
2609:
2607:
2604:
2602:
2599:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2557:
2554:
2552:
2549:
2547:
2544:
2542:
2539:
2537:
2534:
2532:
2529:
2527:
2524:
2522:
2519:
2517:
2514:
2512:
2509:
2507:
2504:
2503:
2501:
2499:
2495:
2489:
2486:
2484:
2481:
2480:
2478:
2476:
2472:
2466:
2463:
2461:
2458:
2456:
2453:
2449:
2446:
2445:
2444:
2441:
2437:
2434:
2433:
2432:
2429:
2428:
2426:
2424:
2420:
2414:
2411:
2409:
2406:
2404:
2401:
2399:
2396:
2394:
2391:
2389:
2386:
2384:
2381:
2379:
2376:
2374:
2371:
2369:
2366:
2364:
2361:
2359:
2356:
2354:
2351:
2349:
2346:
2344:
2341:
2339:
2336:
2334:
2331:
2330:
2328:
2326:
2322:
2316:
2313:
2311:
2308:
2306:
2303:
2301:
2298:
2297:
2295:
2293:
2289:
2284:
2280:
2276:
2272:
2268:
2261:
2256:
2254:
2249:
2247:
2242:
2241:
2238:
2232:
2229:
2226:
2222:
2219:
2218:
2214:
2207:
2203:
2199:
2195:
2191:
2187:
2182:
2178:
2174:
2169:
2164:
2159:
2154:
2150:
2146:
2142:
2138:
2134:
2129:
2125:
2121:
2117:
2113:
2109:
2105:
2101:
2097:
2092:
2088:
2084:
2079:
2074:
2071:(3): 435–42.
2070:
2066:
2062:
2057:
2053:
2049:
2044:
2039:
2034:
2029:
2025:
2021:
2017:
2013:
2009:
2004:
2000:
1996:
1991:
1986:
1981:
1976:
1972:
1968:
1964:
1960:
1956:
1951:
1947:
1943:
1939:
1935:
1931:
1927:
1924:(1): 97–102.
1923:
1919:
1914:
1910:
1906:
1902:
1898:
1894:
1890:
1886:
1882:
1877:
1873:
1869:
1865:
1861:
1858:(2): 666–71.
1857:
1853:
1848:
1844:
1840:
1835:
1830:
1825:
1820:
1816:
1812:
1808:
1804:
1800:
1795:
1791:
1787:
1783:
1779:
1775:
1771:
1768:(3): 233–46.
1767:
1763:
1758:
1754:
1750:
1746:
1742:
1738:
1734:
1729:
1725:
1721:
1717:
1713:
1709:
1705:
1700:
1696:
1692:
1687:
1682:
1678:
1674:
1670:
1665:
1661:
1657:
1652:
1647:
1643:
1639:
1635:
1630:
1626:
1622:
1618:
1614:
1610:
1606:
1602:
1598:
1597:Neurogenetics
1593:
1589:
1585:
1581:
1577:
1573:
1569:
1566:(9): 616–24.
1565:
1561:
1557:
1552:
1548:
1544:
1539:
1534:
1531:(6): 987–92.
1530:
1526:
1522:
1517:
1513:
1509:
1504:
1499:
1495:
1491:
1487:
1482:
1478:
1474:
1470:
1466:
1462:
1458:
1453:
1452:
1447:
1438:
1434:
1430:
1426:
1422:
1418:
1414:
1410:
1406:
1402:
1395:
1392:
1387:
1383:
1379:
1375:
1371:
1367:
1363:
1359:
1355:
1351:
1344:
1341:
1336:
1332:
1327:
1322:
1319:(6): 665–76.
1318:
1314:
1310:
1303:
1300:
1295:
1289:
1286:
1281:
1277:
1271:
1268:
1263:
1259:
1253:
1250:
1246:
1242:
1237:
1235:
1233:
1229:
1225:
1221:
1216:
1214:
1212:
1208:
1201:
1197:
1194:
1193:
1189:
1187:
1185:
1181:
1173:
1171:
1169:
1164:
1162:
1157:
1155:
1151:
1147:
1143:
1139:
1135:
1123:
1118:
1114:
1110:
1107:
1103:
1096:
1094:
1091:
1087:
1083:
1079:
1076:
1072:
1068:
1061:
1059:
1053:
1049:
1045:
1041:
1037:
1033:
1029:
1026:
1020:
1018:
1014:
1010:
1006:
1000:
996:
993:
989:
982:
980:
976:
970:
966:
962:
958:
954:
950:
946:
943:
937:
935:
931:
927:
923:
917:
913:
910:
908:RefSeq (mRNA)
906:
899:
898:
893:
889:
886:
880:
879:
874:
870:
867:
865:
861:
854:
853:
848:
844:
841:
835:
834:
829:
825:
822:
820:
816:
809:
808:
803:
799:
796:
790:
789:
784:
780:
777:
775:
771:
768:
765:
763:
760:
756:
753:
749:
745:
738:
734:
729:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
654:
652:
649:
648:
642:
639:
637:
634:
632:
631:myelin sheath
629:
627:
624:
623:
621:
618:
617:
611:
608:
606:
603:
601:
598:
596:
593:
592:
590:
587:
586:
583:
582:Gene ontology
579:
575:
563:
558:
554:
549:
546:
544:
540:
532:
527:
516:
512:
508:
504:
500:
496:
492:
488:
484:
480:
479:
476:
472:
467:
464:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
417:
414:
410:
405:
402:
401:
398:
396:
392:
390:
389:
385:
384:
381:
379:
375:
371:
367:
363:
355:
350:
346:
342:
337:
327:
323:
316:
309:
303:
296:
288:
284:
280:
275:
271:
266:
262:
254:
249:
245:
241:
236:
226:
222:
215:
208:
202:
195:
191:
185:
181:
177:
172:
168:
163:
159:
155:
151:
147:
143:
139:
135:
131:
127:
123:
119:
111:
106:
99:
94:
89:
78:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
2787:expanding it
2776:
2761:
2749:
2447:
2283:cytoskeleton
2273:(other than
2192:(1): 223–6.
2189:
2185:
2140:
2136:
2102:(4): 352–3.
2099:
2095:
2068:
2064:
2015:
2011:
1962:
1958:
1921:
1917:
1884:
1880:
1855:
1851:
1806:
1802:
1765:
1761:
1736:
1732:
1710:(1): 136–9.
1707:
1703:
1679:(4): 871–8.
1676:
1672:
1644:(1): 161–9.
1641:
1637:
1600:
1596:
1563:
1559:
1528:
1524:
1493:
1490:Arch. Neurol
1489:
1463:(4): 125–8.
1460:
1457:Trends Genet
1456:
1404:
1400:
1394:
1353:
1349:
1343:
1316:
1312:
1302:
1288:
1279:
1270:
1261:
1252:
1177:
1174:Interactions
1165:
1158:
1145:
1133:
1132:
1058:NP_001346049
1055:
1048:NP_001346048
1044:NP_001346047
1040:NP_001346046
1032:NP_001277490
1013:NP_001291933
1009:NP_001122306
1002:
979:NM_001359120
975:NM_001359119
972:
965:NM_001359118
961:NM_001359117
957:NM_001290562
953:NM_001290561
934:NM_001305004
930:NM_001128834
919:
895:
876:
850:
831:
805:
786:
766:
761:
393:
386:
352:135,740,482
339:135,723,420
251:103,792,619
238:103,773,718
113:External IDs
72:
2498:Tetraspanin
1603:(1): 1–16.
672:myelination
447:spinal cord
91:Identifiers
2826:Categories
2702:Presenilin
2096:Hum. Genet
1247:, May 2017
1226:, May 2017
1202:References
451:C1 segment
397:(ortholog)
134:HomoloGene
2750:see also
2729:Dysferlin
1421:0360-4012
1370:0364-3190
1142:Mutations
1036:NP_035253
1017:NP_955772
1005:NP_000524
949:NM_011123
926:NM_000533
922:NM_199478
752:Orthologs
142:GeneCards
2687:Calnexin
2292:Arrestin
2124:35833817
1946:33666906
1790:24450880
1625:32631043
1617:15627202
1588:38917872
1580:14572140
1547:10767322
1512:10520936
1477:10203813
1437:33666906
1335:19067971
1243:–
1222:–
1190:See also
1180:interact
1106:Wikidata
731:Sources:
641:membrane
2779:protein
2671:TSPAN34
2666:TSPAN33
2661:TSPAN32
2656:TSPAN31
2651:TSPAN30
2646:TSPAN29
2641:TSPAN28
2636:TSPAN27
2631:TSPAN26
2626:TSPAN25
2621:TSPAN24
2616:TSPAN23
2611:TSPAN22
2606:TSPAN21
2601:TSPAN20
2596:TSPAN19
2591:TSPAN18
2586:TSPAN17
2581:TSPAN16
2576:TSPAN15
2571:TSPAN14
2566:TSPAN13
2561:TSPAN12
2556:TSPAN11
2551:TSPAN10
2279:enzymes
2269:: cell
2267:Protein
2206:3768366
2177:3467339
2145:Bibcode
2116:3457761
2087:2773936
2078:1683421
2052:2480601
2020:Bibcode
1999:2479017
1967:Bibcode
1938:2467009
1909:4367384
1901:2449536
1872:2441695
1843:1715570
1811:Bibcode
1782:1711121
1753:1708672
1724:1707231
1695:1384324
1686:1682779
1660:1376966
1651:1682866
1429:2467009
1386:9751765
1378:6083474
1245:Ensembl
1224:Ensembl
1140:(PLP).
864:UniProt
819:Ensembl
758:Species
737:QuickGO
372:pattern
98:Aliases
2546:TSPAN9
2541:TSPAN8
2536:TSPAN7
2531:TSPAN6
2526:TSPAN5
2521:TSPAN4
2516:TSPAN3
2511:TSPAN2
2506:TSPAN1
2423:Myelin
2413:MS4A18
2408:MS4A15
2403:MS4A14
2398:MS4A13
2393:MS4A12
2388:MS4A10
2378:MS4A8B
2368:MS4A6E
2363:MS4A6A
2353:MS4A4E
2348:MS4A4A
2281:, and
2227:(MeSH)
2204:
2175:
2168:387231
2165:
2122:
2114:
2085:
2075:
2050:
2043:298509
2040:
1997:
1990:298228
1987:
1944:
1936:
1907:
1899:
1870:
1841:
1831:
1788:
1780:
1751:
1722:
1693:
1683:
1658:
1648:
1623:
1615:
1586:
1578:
1545:
1510:
1475:
1435:
1427:
1419:
1384:
1376:
1368:
1333:
1154:myelin
1092:search
1090:PubMed
897:P60202
878:P60201
774:Entrez
543:BioGPS
230:Xq22.2
122:300401
2777:This
2712:PSEN2
2707:PSEN1
2383:MS4A9
2373:MS4A7
2358:MS4A5
2343:MS4A3
2338:MS4A2
2333:MS4A1
2310:ARRB2
2305:ARRB1
2120:S2CID
1942:S2CID
1905:S2CID
1834:52341
1786:S2CID
1621:S2CID
1584:S2CID
1433:S2CID
1382:S2CID
1182:with
807:18823
767:Mouse
762:Human
733:Amigo
395:Mouse
388:Human
335:Start
270:Mouse
234:Start
167:Human
130:97623
2783:stub
2739:OTOF
2734:STRC
2448:PLP1
2436:PMP2
2315:ARR3
2202:PMID
2173:PMID
2112:PMID
2083:PMID
2048:PMID
1995:PMID
1934:PMID
1897:PMID
1868:PMID
1839:PMID
1778:PMID
1749:PMID
1720:PMID
1691:PMID
1656:PMID
1613:PMID
1576:PMID
1543:PMID
1508:PMID
1473:PMID
1425:PMID
1417:ISSN
1374:PMID
1366:ISSN
1331:PMID
1196:PLP2
1168:MITF
1146:PLP1
788:5354
435:pons
378:Bgee
326:Band
287:Chr.
225:Band
184:Chr.
146:PLP1
118:OMIM
105:PLP1
75:2XPG
56:RCSB
53:PDBe
22:PLP1
2719:HFE
2300:SAG
2194:doi
2190:862
2163:PMC
2153:doi
2104:doi
2073:PMC
2038:PMC
2028:doi
1985:PMC
1975:doi
1926:doi
1889:doi
1860:doi
1856:146
1829:PMC
1819:doi
1770:doi
1766:120
1741:doi
1737:371
1712:doi
1681:PMC
1646:PMC
1605:doi
1568:doi
1533:doi
1498:doi
1465:doi
1409:doi
1358:doi
1321:doi
1144:in
348:End
247:End
150:OMA
138:448
126:MGI
46:PDB
2828::
2277:,
2200:.
2188:.
2171:.
2161:.
2151:.
2141:83
2139:.
2135:.
2118:.
2110:.
2100:72
2098:.
2081:.
2069:45
2067:.
2063:.
2046:.
2036:.
2026:.
2016:86
2014:.
2010:.
1993:.
1983:.
1973:.
1963:86
1961:.
1957:.
1940:.
1932:.
1922:22
1920:.
1903:.
1895:.
1885:18
1883:.
1866:.
1854:.
1837:.
1827:.
1817:.
1807:88
1805:.
1801:.
1784:.
1776:.
1764:.
1747:.
1735:.
1718:.
1708:38
1706:.
1689:.
1677:51
1675:.
1671:.
1654:.
1642:51
1640:.
1636:.
1619:.
1611:.
1599:.
1582:.
1574:.
1564:18
1562:.
1558:.
1541:.
1527:.
1523:.
1506:.
1494:56
1492:.
1488:.
1471:.
1461:15
1459:.
1431:.
1423:.
1415:.
1405:22
1403:.
1380:.
1372:.
1364:.
1352:.
1329:.
1317:21
1315:.
1311:.
1278:.
1260:.
1231:^
1210:^
1186:.
1170:.
735:/
354:bp
341:bp
253:bp
240:bp
148:;
144::
140:;
136::
132:;
128::
124:;
120::
2814:e
2807:t
2800:v
2789:.
2285:)
2259:e
2252:t
2245:v
2208:.
2196::
2179:.
2155::
2147::
2126:.
2106::
2089:.
2054:.
2030::
2022::
2001:.
1977::
1969::
1948:.
1928::
1911:.
1891::
1874:.
1862::
1845:.
1821::
1813::
1792:.
1772::
1755:.
1743::
1726:.
1714::
1697:.
1662:.
1627:.
1607::
1601:6
1590:.
1570::
1549:.
1535::
1529:9
1514:.
1500::
1479:.
1467::
1439:.
1411::
1388:.
1360::
1354:9
1337:.
1323::
1296:.
1282:.
1264:.
272:)
169:)
152::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.