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QRICH2

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FLJ25737 mRNA sequences perfectly match with two regions on the QRICH2 mRNA (bp 3157-4302 on QRICH2 match with bp 1-1146 on FLJ25737, bp 4998-5307 on QRICH2 match with bp 1140-1499 on FLJ25737). However, FLJ25737 locates on chromosome 7 and QRICH2 locates on chromosome 17.
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The function of QRICH2 protein is mostly unknown. QRICH2 has been shown to belong to the common expression groups on human chromosome 17. The following genes belonged to the common expression groups on chromosome 17:
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QRICH2 protein has well conserved orthologs in many species. The orthologous protein sequences match very well at the region where the high molecular weight Glutenin domain and ATPase involved domain is.
1484:. The high expression of QRICH2 gene in testis may suggest that QRICH2 protein has some functions related to hormone production in males. QRICH2 protein has some sequence similarities with the 953:, and this result is confirmed by the Gene Expression Profile for mouse and dog too. The subcellular location of QRICH2 protein is in the nucleus. QRICH2 is a soluble protein, its average 255: 154: 567: 548: 77: 841:
on human chromosome 17. The function of QRICH2 protein is mostly unknown, but it has been shown that QRICH2 gene contains a high molecular weight
1569: 1928: 1551: 1871:"The gene expression profiles of canine mammary cancer cells grown with carcinoma-associated fibroblasts (CAFs) as a co-culture in vitro" 241: 778: 771: 218: 1727: 1538: 1517: 1465: 140: 115: 1534: 1666: 1513: 57: 254: 153: 247: 146: 612: 65: 1590: 593: 129: 1823: 44: 754: 707: 686: 909:
QRICH2 mRNA is 5411 bp long, and its chromosomal location in human is 17q25.1. QRICH2 mRNA has 19
89: 733: 682: 1902: 1851: 1733: 1723: 37: 1892: 1882: 1869:
Król M, Pawłowski KM, Szyszko K, Maciejewski H, Dolka I, Manuali E, Jank M, Motyl T (2012).
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Chou PY, Fasman GD (1978). "Advances in Enzymology and Related Areas of Molecular Biology".
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and 13% is turning. The human tissue type with the highest level of QRICH2 expression is
1827: 1897: 1870: 1846: 1811: 954: 1610:. National Center for Biotechnology Information, Nucleotide Database. 26 January 2014. 957:
is -0.5995. QRICH2 protein interact with a number of other proteins including SSSCA1,
1922: 1481: 1751: 1710:. Prediction of the secondary structure of proteins from their amino acid sequence. 1621: 69: 1812:"Identification of common differentially expressed genes in urinary bladder cancer" 1622:"NCBI Gene Expression Omnibus (GEO): QRICH2 expression in various tissues in human" 1607: 327: 106: 1836: 93: 1796: 1574:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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involved domain (amino acid 1036-1413). QRICH2 locates between UBAL D2 gene and
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structure on QRICH2 mRNA because there isn't any complementary RNA sequences.
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QRICH2 protein is 1663 amino acids long, and 10.9% of the amino acids are
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Zaravinos A, Lambrou GI, Boulalas I, Delakas D, Spandidos DA (2011).
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and it contains two main function domains: a high molecular weight
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National Center for Biotechnology Information, Gene Database
1476:. QRICH2 may also be an up-regulated gene involved in cell 1766:"SOSUI, Classification and Secondary Structure Prediction" 317: 941:(Q). 38% of the QRICH2 protein secondary structure is 482: 849:
involved domain. QRICH2 gene is highly expressed in
747: 726: 700: 675: 1530: 1528: 1526: 1509: 1507: 1505: 264: 163: 1602: 1600: 1492:N(1)-acetyl-like protein 1 in several species. 16:Protein-coding gene in the species Homo sapiens 1799:. NCBI Nucleotide Database. 13 September 2006. 1535:GRCm38: Ensembl release 89: ENSMUSG00000070331 857:location of QRICH2 protein is in the nucleus. 1777: 1775: 925:gene on chromosome 17. There is no predicted 8: 1585: 1583: 1514:GRCh38: Ensembl release 89: ENSG00000129646 1752:"Expression data (EST profile) for QRICH2" 508: 305: 204: 101: 1896: 1886: 1845: 1835: 1768:. Expasy Bioinformatics Resource Portal. 1143: 1056: 996: 859: 837:that in humans is decoded by the QRICH2 1593:. Genecards, The Human Gene Compendium. 1501: 18: 269: 230: 225: 168: 127: 122: 7: 1785:. Basic Local Alignment Search Tool. 1708:Adv. Enzymol. Relat. Areas Mol. Biol 917:domain (amino acid 446-979) and an 744: 723: 697: 672: 648: 629: 603: 584: 558: 539: 487: 405: 343: 322: 14: 1695:. San Diego Supercomputer Center. 253: 246: 240: 217: 152: 145: 139: 114: 471:More reference expression data 383:right hemisphere of cerebellum 1: 238: 137: 1929:Genes on human chromosome 17 1837:10.1371/journal.pone.0018135 375:stromal cell of endometrium 367:right lobe of thyroid gland 1945: 779:Chr 11: 116.33 – 116.36 Mb 387:left lobe of thyroid gland 48:, glutamine rich 2, SPGF35 1720:10.1002/9780470122921.ch2 1608:"NCBI Nucleotide: QRICH2" 1570:"Mouse PubMed Reference:" 1552:"Human PubMed Reference:" 1115:Protein piccolo isoform 1 817: 812: 808: 801: 785: 766: 751: 730: 719: 704: 679: 668: 655: 651: 636: 632: 623: 610: 606: 591: 587: 578: 565: 561: 546: 542: 533: 518: 511: 507: 495: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 831:Glutamine-rich protein 2 772:Chr 17: 76.27 – 76.31 Mb 1667:"Nucleic acid dot plot" 1089:Spermine like protein 1 1888:10.1186/1746-6148-8-35 1265:Ailuropoda melanoleuca 1219:Canis lupus familiaris 863:NCBI Reference Number 1636:"PSORT II Prediction" 882:Protein: NP_115510.1 379:cerebellar hemisphere 232:Chromosome 11 (mouse) 130:Chromosome 17 (human) 1155:(Million years ago) 1828:2011PLoSO...618135Z 1650:"NCBI Gene: QRICH2" 1591:"Genecards: QRICH2" 1196:Nomascus leucogenys 1159:Accession(Protein) 1066:Accession(Protein) 425:seminiferous tubule 395:ganglionic eminence 1288:Otolemur garnettii 1242:Loxodonta africana 880:mRNA: NM_032134.1 613:ENSMUSG00000070331 94:QRICH2 - orthologs 1673:on 19 August 2015 1448: 1447: 1173:Rattus norvegicus 1137: 1136: 1051: 1050: 902: 901: 888:Protein: 1663 aa 872:Molecular weight 828: 827: 824: 823: 797: 796: 762: 761: 741: 740: 715: 714: 694: 693: 664: 663: 645: 644: 619: 618: 600: 599: 574: 573: 555: 554: 503: 502: 499: 498: 477: 476: 464: 463: 402: 401: 300: 299: 199: 198: 1936: 1911: 1910: 1900: 1890: 1866: 1860: 1859: 1849: 1839: 1807: 1801: 1800: 1793: 1787: 1786: 1779: 1770: 1769: 1762: 1756: 1755: 1748: 1742: 1741: 1703: 1697: 1696: 1689: 1683: 1682: 1680: 1678: 1669:. Archived from 1663: 1657: 1656: 1646: 1640: 1639: 1632: 1626: 1625: 1618: 1612: 1611: 1604: 1595: 1594: 1587: 1578: 1577: 1566: 1560: 1559: 1548: 1542: 1532: 1521: 1511: 1144: 1057: 1006:Accession(mRNA) 997: 989: 988: 984: 860: 810: 809: 781: 774: 757: 745: 736: 724: 720:RefSeq (protein) 710: 698: 689: 673: 649: 630: 604: 585: 559: 540: 509: 488: 473: 453:secondary oocyte 413: 411:Top expressed in 406: 371:ventricular zone 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 1944: 1943: 1939: 1938: 1937: 1935: 1934: 1933: 1919: 1918: 1915: 1914: 1868: 1867: 1863: 1809: 1808: 1804: 1797:"NCBI FLJ25737" 1795: 1794: 1790: 1781: 1780: 1773: 1764: 1763: 1759: 1754:. Unigene NCBI. 1750: 1749: 1745: 1730: 1705: 1704: 1700: 1691: 1690: 1686: 1676: 1674: 1665: 1664: 1660: 1648: 1647: 1643: 1634: 1633: 1629: 1620: 1619: 1615: 1606: 1605: 1598: 1589: 1588: 1581: 1568: 1567: 1563: 1550: 1549: 1545: 1533: 1524: 1512: 1503: 1498: 1457: 1403:Gorilla gorilla 1334:Cavia porcellus 1142: 995: 990: 986: 982: 980: 979: 935: 907: 819:View/Edit Mouse 814:View/Edit Human 777: 770: 767:Location (UCSC) 753: 732: 706: 685: 681: 594:ENSG00000129646 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1942: 1940: 1932: 1931: 1921: 1920: 1913: 1912: 1861: 1802: 1788: 1771: 1757: 1743: 1728: 1698: 1684: 1658: 1641: 1627: 1613: 1596: 1579: 1561: 1543: 1522: 1500: 1499: 1497: 1494: 1456: 1453: 1446: 1445: 1442: 1439: 1436: 1435:NP_001028439.1 1433: 1430: 1427: 1423: 1422: 1419: 1416: 1413: 1410: 1407: 1404: 1400: 1399: 1396: 1393: 1390: 1389:XP_003913523.1 1387: 1384: 1381: 1377: 1376: 1373: 1370: 1367: 1366:XP_003997276.1 1364: 1361: 1358: 1354: 1353: 1350: 1347: 1344: 1341: 1338: 1335: 1331: 1330: 1327: 1324: 1321: 1320:XP_003131230.1 1318: 1315: 1312: 1308: 1307: 1304: 1301: 1298: 1297:XP_003785524.1 1295: 1292: 1289: 1285: 1284: 1281: 1278: 1275: 1274:XP_002919929.1 1272: 1269: 1266: 1262: 1261: 1258: 1255: 1252: 1251:XP_003417424.1 1249: 1246: 1243: 1239: 1238: 1235: 1232: 1229: 1226: 1223: 1220: 1216: 1215: 1212: 1209: 1206: 1205:XP_003279182.2 1203: 1200: 1197: 1193: 1192: 1189: 1186: 1183: 1180: 1177: 1174: 1170: 1169: 1166: 1163: 1160: 1157: 1151: 1148: 1141: 1138: 1135: 1134: 1131: 1128: 1125: 1122: 1119: 1116: 1113: 1109: 1108: 1105: 1102: 1099: 1096: 1093: 1092:NP_001012998.2 1090: 1087: 1083: 1082: 1079: 1076: 1073: 1070: 1067: 1064: 1061: 1049: 1048: 1045: 1042: 1039: 1036: 1033: 1030: 1027: 1023: 1022: 1019: 1016: 1013: 1010: 1007: 1004: 1001: 994: 991: 978: 975: 955:hydrophobicity 934: 931: 906: 903: 900: 899: 896: 893: 890: 886:mRNA: 5411 bp 884: 877: 876: 873: 870: 867: 864: 845:domain and an 826: 825: 822: 821: 816: 806: 805: 799: 798: 795: 794: 792: 790: 783: 782: 775: 768: 764: 763: 760: 759: 749: 748: 742: 739: 738: 728: 727: 721: 717: 716: 713: 712: 702: 701: 695: 692: 691: 677: 676: 670: 666: 665: 662: 661: 653: 652: 646: 643: 642: 634: 633: 627: 621: 620: 617: 616: 608: 607: 601: 598: 597: 589: 588: 582: 576: 575: 572: 571: 563: 562: 556: 553: 552: 544: 543: 537: 531: 530: 525: 520: 516: 515: 505: 504: 501: 500: 497: 496: 493: 492: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 445:primary oocyte 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1941: 1930: 1927: 1926: 1924: 1917: 1908: 1904: 1899: 1894: 1889: 1884: 1880: 1876: 1872: 1865: 1862: 1857: 1853: 1848: 1843: 1838: 1833: 1829: 1825: 1822:(4): e18135. 1821: 1817: 1813: 1806: 1803: 1798: 1792: 1789: 1784: 1778: 1776: 1772: 1767: 1761: 1758: 1753: 1747: 1744: 1739: 1735: 1731: 1729:9780470122921 1725: 1721: 1717: 1713: 1709: 1702: 1699: 1694: 1693:"CHOFAS tool" 1688: 1685: 1672: 1668: 1662: 1659: 1655: 1651: 1645: 1642: 1637: 1631: 1628: 1623: 1617: 1614: 1609: 1603: 1601: 1597: 1592: 1586: 1584: 1580: 1575: 1571: 1565: 1562: 1557: 1553: 1547: 1544: 1540: 1536: 1531: 1529: 1527: 1523: 1519: 1515: 1510: 1508: 1506: 1502: 1495: 1493: 1491: 1487: 1483: 1482:morphogenesis 1480:and cellular 1479: 1475: 1471: 1467: 1463: 1454: 1452: 1443: 1440: 1437: 1434: 1431: 1428: 1425: 1424: 1420: 1417: 1414: 1411: 1408: 1405: 1402: 1401: 1397: 1394: 1391: 1388: 1385: 1382: 1379: 1378: 1374: 1371: 1368: 1365: 1362: 1359: 1356: 1355: 1351: 1348: 1345: 1342: 1339: 1336: 1333: 1332: 1328: 1325: 1322: 1319: 1316: 1313: 1310: 1309: 1305: 1302: 1299: 1296: 1293: 1290: 1287: 1286: 1282: 1279: 1276: 1273: 1270: 1267: 1264: 1263: 1259: 1256: 1253: 1250: 1247: 1244: 1241: 1240: 1236: 1233: 1230: 1227: 1224: 1221: 1218: 1217: 1213: 1210: 1207: 1204: 1201: 1198: 1195: 1194: 1190: 1187: 1184: 1181: 1178: 1175: 1172: 1171: 1167: 1164: 1161: 1158: 1156: 1152: 1149: 1146: 1145: 1139: 1132: 1129: 1126: 1123: 1120: 1117: 1114: 1111: 1110: 1106: 1103: 1100: 1097: 1094: 1091: 1088: 1085: 1084: 1080: 1077: 1074: 1071: 1068: 1065: 1063:Protein name 1062: 1059: 1058: 1055: 1046: 1043: 1040: 1037: 1034: 1031: 1028: 1025: 1024: 1020: 1017: 1014: 1011: 1008: 1005: 1002: 999: 998: 992: 985: 976: 974: 972: 968: 964: 960: 956: 952: 948: 944: 940: 932: 930: 928: 924: 920: 916: 912: 904: 897: 894: 891: 889: 885: 883: 879: 878: 874: 871: 868: 865: 862: 861: 858: 856: 852: 848: 844: 840: 836: 832: 820: 815: 811: 807: 804: 800: 793: 791: 788: 784: 780: 776: 773: 769: 765: 758: 756: 750: 746: 743: 737: 735: 729: 725: 722: 718: 711: 709: 703: 699: 696: 690: 688: 684: 678: 674: 671: 669:RefSeq (mRNA) 667: 660: 659: 654: 650: 647: 641: 640: 635: 631: 628: 626: 622: 615: 614: 609: 605: 602: 596: 595: 590: 586: 583: 581: 577: 570: 569: 564: 560: 557: 551: 550: 545: 541: 538: 536: 532: 529: 526: 524: 521: 517: 514: 510: 506: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 271:11|11 E2 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 1916: 1878: 1875:BMC Vet. Res 1874: 1864: 1819: 1815: 1805: 1791: 1783:"NCBI BLAST" 1760: 1746: 1711: 1707: 1701: 1687: 1675:. Retrieved 1671:the original 1661: 1653: 1644: 1630: 1616: 1573: 1564: 1555: 1546: 1458: 1449: 1426:Mus musculus 1412:XP_004041087 1380:Papio anubis 1343:XP_003461498 1154: 1150:Common name 1052: 936: 908: 887: 881: 830: 829: 755:NP_001028439 752: 731: 708:NM_001033267 705: 687:NM_001388453 680: 656: 637: 611: 592: 566: 547: 527: 522: 429:spermatocyte 363:right testis 333: 326: 292:116,357,067 279:116,332,151 53:External IDs 1429:House mouse 1357:Felis catus 1228:XP_533125.3 1182:XP_577148.4 1162:Length(aa) 1153:Divergence 1118:NP_149015.2 1069:Length(aa) 1009:Length(bp) 943:alpha-helix 895:180.8 kdal 855:subcellular 457:granulocyte 391:sural nerve 359:left testis 191:76,308,276 178:76,274,049 31:Identifiers 1714:: 45–148. 1541:, May 2017 1520:, May 2017 1496:References 1486:spermidine 1468:, QRICH2, 1337:Guinea pig 1311:Sus scrofa 1003:Gene name 947:beta-sheet 853:, and the 337:(ortholog) 74:HomoloGene 1176:Brown rat 1168:Coverage 1165:Identity 1140:Orthologs 1081:Location 1078:Coverage 1075:Identity 1021:Location 1018:Coverage 1015:Identity 945:, 39% is 939:Glutamine 927:stem loop 869:location 734:NP_115510 683:NM_032134 513:Orthologs 421:spermatid 82:GeneCards 1923:Category 1907:22453032 1856:21483740 1816:PLOS ONE 1537:– 1516:– 1490:spermine 1478:adhesion 1455:Function 1291:Bushbaby 1245:Elephant 1147:Species 1133:7q11.23 1124:3.00e-10 1098:6.00e-46 1072:E-value 1060:Species 1032:AK058102 1029:FLJ25373 1012:E-value 1000:Species 993:paralogs 977:Homology 915:Glutenin 892:17q25.1 843:Glutenin 803:Wikidata 449:epiblast 1898:3355042 1847:3070717 1824:Bibcode 1539:Ensembl 1518:Ensembl 1470:ANAPC11 1406:Gorilla 1107:Xq21.1 933:Protein 923:PRPSAP1 866:Length 835:protein 625:UniProt 580:Ensembl 519:Species 312:pattern 170:17q25.1 70:2684912 38:Aliases 1905:  1895:  1881:: 35. 1854:  1844:  1738:364941 1736:  1726:  1677:14 May 1383:Babbon 1199:Gibbon 981:": --> 951:testis 919:ATPase 851:testis 847:ATPase 789:search 787:PubMed 658:Q3V2A7 639:Q9H0J4 568:217341 535:Entrez 483:BioGPS 441:embryo 437:embryo 433:zygote 86:QRICH2 62:618304 45:QRICH2 22:QRICH2 1462:NCOR1 1268:Panda 1112:Human 1086:Human 1026:Human 971:SNAI1 967:NUP98 963:GAPDH 959:TSSC1 911:exons 898:6.25 833:is a 549:84074 528:Mouse 523:Human 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:12951 1903:PMID 1852:PMID 1734:PMID 1724:ISBN 1679:2013 1474:PER1 1472:and 1466:GFAP 1444:30% 1432:92.3 1421:30% 1398:97% 1392:2043 1375:98% 1369:1755 1363:94.2 1352:99% 1346:1852 1340:92.3 1329:99% 1323:1983 1317:94.2 1314:Boar 1306:99% 1300:1963 1283:99% 1277:1903 1271:94.2 1260:99% 1254:1973 1248:98.7 1237:99% 1231:1936 1225:94.2 1214:99% 1208:1768 1202:20.4 1191:99% 1185:1971 1179:92.3 1121:5142 1047:ch7 1035:1499 983:edit 969:and 905:Gene 839:gene 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 1893:PMC 1883:doi 1842:PMC 1832:doi 1716:doi 1441:77% 1438:592 1418:99% 1415:507 1409:8.8 1395:80% 1372:61% 1360:Cat 1349:61% 1326:63% 1303:63% 1280:64% 1257:65% 1234:67% 1222:Dog 1211:80% 1188:51% 1130:33% 1127:30% 1104:39% 1101:34% 1095:632 1044:27% 1041:99% 1038:0.0 875:PI 491:n/a 288:End 187:End 90:OMA 66:MGI 1925:: 1901:. 1891:. 1877:. 1873:. 1850:. 1840:. 1830:. 1818:. 1814:. 1774:^ 1732:. 1722:. 1712:47 1652:. 1599:^ 1582:^ 1572:. 1554:. 1525:^ 1504:^ 1464:, 1386:29 1294:74 973:. 965:, 961:, 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 1909:. 1885:: 1879:8 1858:. 1834:: 1826:: 1820:6 1740:. 1718:: 1681:. 1638:. 1624:. 1576:. 1558:. 1488:/ 987:] 212:) 109:) 92::

Index

Aliases
QRICH2
OMIM
618304
MGI
2684912
HomoloGene
12951
GeneCards
QRICH2
OMA
QRICH2 - orthologs
Human
Chromosome 17 (human)
Chr.
Chromosome 17 (human)
Chromosome 17 (human)
Genomic location for QRICH2
Genomic location for QRICH2
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.
Chromosome 11 (mouse)
Genomic location for QRICH2
Genomic location for QRICH2
Band
bp

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