258:
235:
132:
157:
2363:
1275:
patterning of these receptors during embryological development. The signals from the nerve and RYR1 activity appear to counterbalance each other. When RYR1 is eliminated, the acetylcholine receptor clusters appear in an abnormally narrow pattern, yet without signals from the nerve, the clusters are scattered and broad. Although their direct role is still unknown, RYR1 is required for proper distribution of acetylcholine receptor clusters.
509:
264:
163:
40:
1271:
essential for differentiation. This coincides with the observation that without RYR1 present, muscle cells appear in smaller groups, are underdeveloped, and lack organization. Fiber type composition is also affected, with less type 1 muscle fibers when there are decreased amounts of RYR1. These findings demonstrate RYR1 has a non-contractile role during muscle development.
1270:
RYR1 plays a signaling role during embryonic skeletal myogenesis. A correlation exists between RYR1-mediated Ca2+ signaling and the expression of multiple molecules involved in key myogenic signaling pathways. Of these, more than 10 differentially expressed genes belong to the Wnt family which are
1274:
RYR1 is mechanically linked to neuromuscular junctions for the calcium release-calcium induced biological process. While nerve-derived signals are required for acetylcholine receptor cluster distribution, there is evidence to suggest RYR1 activity is an important mediator in the formation and
1999:
Hwang SY, Wei J, Westhoff JH, Duncan RS, Ozawa F, Volpe P, Inokuchi K, Koulen P (August 2003). "Differential functional interaction of two Vesl/Homer protein isoforms with ryanodine receptor type 1: a novel mechanism for control of intracellular calcium signaling".
1719:
Böhm J, Leshinsky-Silver E, Vassilopoulos S, Le Gras S, Lerman-Sagie T, Ginzberg M, Jost B, Lev D, Laporte J (October 2012). "Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation".
1763:
Fruen BR, Balog EM, Schafer J, Nitu FR, Thomas DD, Cornea RL (January 2005). "Direct detection of calmodulin tuning by ryanodine receptor channel targets using a Ca2+-sensitive acrylodan-labeled calmodulin".
1267:(L-type calcium channels) within the sarcolemma of the T-tubule, which opens in response to depolarization, and thus effectively means that the RYR1 channel opens in response to depolarization of the cell.
2243:
Treves S, Anderson AA, Ducreux S, Divet A, Bleunven C, Grasso C, Paesante S, Zorzato F (October 2005). "Ryanodine receptor 1 mutations, dysregulation of calcium homeostasis and neuromuscular disorders".
1459:
Fujii J, Otsu K, Zorzato F, de Leon S, Khanna VK, Weiler JE, O'Brien PJ, MacLennan DH (July 1991). "Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia".
1911:"Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor"
3187:
4097:
1627:
Willemse H, Theodoratos A, Smith PN, Dulhunty AF (February 2016). "Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition".
3832:
3084:
3017:
271:
170:
2362:
4627:
942:
93:
923:
4028:
4011:
4006:
4001:
3996:
1570:
Filipova D, Walter AM, Gaspar JA, Brunn A, Linde NF, Ardestani MA, Deckert M, Hescheler J, Pfitzer G, Sachinidis A, Papadopoulos S (April 2016).
4033:
3131:
2403:
4647:
2342:
1441:
1423:
4085:
3266:
3983:
3004:
2420:
257:
3769:
1150:
1157:
2122:
Caswell AH, Motoike HK, Fan H, Brandt NR (January 1999). "Location of ryanodine receptor binding site on skeletal muscle triadin".
234:
1556:
2083:"Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin"
4362:
3361:
3139:
2455:
1410:
1389:
1303:
myopathy, a benign congenital myopathy. Alternatively spliced transcripts encoding different isoforms have been demonstrated.
4384:
2311:
156:
131:
1406:
4593:
2504:
1502:
Wu S, Ibarra MC, Malicdan MC, Murayama K, Ichihara Y, Kikuchi H, Nonaka I, Noguchi S, Hayashi YK, Nishino I (June 2006).
1385:
3959:
2871:
73:
4657:
4234:
1316:
270:
169:
2412:
2396:
1572:"Corrigendum: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel"
4588:
2798:
2335:
2159:"Association of triadin with the ryanodine receptor and calsequestrin in the lumen of the sarcoplasmic reticulum"
263:
162:
4578:
2839:
2715:
2292:
1264:
987:
81:
4583:
968:
1909:
Bultynck G, De Smet P, Rossi D, Callewaert G, Missiaen L, Sorrentino V, De Smedt H, Parys JB (March 2001).
4614:
2606:
2593:
2580:
2560:
2547:
2512:
1773:
1515:
1288:
4652:
2389:
2303:
2298:
1256:
145:
2487:
2328:
1822:
1583:
1468:
1292:
60:
1778:
1520:
2381:
1112:
1061:
2200:"Functional interaction of the cytoplasmic domain of triadin with the skeletal ryanodine receptor"
3954:
2830:
2477:
2288:
2269:
1745:
1652:
1362:
1252:
1225:
105:
1133:
1108:
1082:
1057:
2992:
2261:
2221:
2180:
2139:
2104:
2063:
2017:
1981:
1940:
1891:
1850:
1791:
1737:
1701:
1644:
1609:
1535:
1484:
1260:
53:
1870:"FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes"
3761:
2742:
2253:
2211:
2170:
2131:
2094:
2053:
2009:
1971:
1958:
Gaburjakova M, Gaburjakova J, Reiken S, Huang F, Marx SO, Rosemblit N, Marks AR (May 2001).
1930:
1922:
1881:
1840:
1830:
1783:
1729:
1691:
1683:
1636:
1599:
1591:
1525:
1476:
1296:
350:
281:
225:
180:
4297:
2437:
2315:
1233:
508:
325:
101:
1826:
1587:
1472:
4093:
2780:
1935:
1910:
1845:
1810:
1696:
1671:
1604:
1571:
39:
2013:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
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555:
550:
4641:
4631:
4047:
3720:
2198:
Groh S, Marty I, Ottolia M, Prestipino G, Chapel A, Villaz M, Ronjat M (April 1999).
1307:
may be the only known drug that is effective during cases of malignant hyperthermia.
537:
2273:
4400:
3791:
1809:
Cornea RL, Nitu F, Gruber S, Kohler K, Satzer M, Thomas DD, Fruen BR (April 2009).
1749:
1687:
1656:
343:
122:
2308:
85:
2040:
Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN (November 2002).
109:
4330:
4325:
4320:
4315:
4202:
4041:
2416:
1446:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1428:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2081:
Lee JM, Rho SH, Shin DW, Cho C, Park WJ, Eom SH, Ma J, Kim DH (February 2004).
1815:
Proceedings of the
National Academy of Sciences of the United States of America
426:
4310:
3676:
3044:
3012:
2371:: Crystal structure of calmodulin in complex with a ryanodine receptor peptide
2257:
1733:
1640:
1323:
1304:
1300:
242:
139:
89:
2216:
2199:
1672:"An explant muscle model to examine the refinement of the synaptic landscape"
64:, CCO, MHS, MHS1, PPP1R137, RYDR, RYR, RYR-1, SKRR, ryanodine receptor 1, KDS
4395:
4305:
2175:
2158:
1835:
1504:"Central core disease is due to RYR1 mutations in more than 90% of patients"
1480:
887:
486:
364:
309:
296:
208:
195:
97:
2265:
2225:
2108:
2099:
2082:
2067:
2058:
2041:
2021:
1985:
1976:
1959:
1944:
1895:
1886:
1869:
1854:
1795:
1741:
1705:
1648:
1613:
1539:
1530:
1503:
2184:
2143:
1488:
1197:
1192:
4408:
3756:
2735:
2730:
2725:
2720:
2652:
2647:
1811:"FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel"
1181:
1032:
1013:
773:
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
2135:
4535:
4292:
4128:
2629:
2624:
2619:
1229:
999:
954:
2304:
GeneReviews/NCBI/NIH/UW entry on
Malignant Hyperthermia Susceptibility
1926:
1787:
1595:
4212:
4207:
3941:
3936:
3882:
3877:
3693:
3681:
3671:
3666:
3654:
3649:
3644:
3531:
3526:
3521:
3413:
3349:
3344:
3339:
3334:
3329:
3324:
3319:
3254:
3249:
3239:
3234:
3229:
3180:
3175:
3165:
3160:
3037:
3032:
3027:
3022:
2928:
2923:
2918:
2908:
2903:
2893:
2888:
2818:
2813:
2808:
2803:
2706:
2701:
2696:
2691:
2679:
2674:
2669:
2664:
2573:
2540:
2535:
2530:
2525:
1343:
1338:
1333:
1328:
1259:, as well as a connection between the sarcoplasmic reticulum and the
1165:
909:
17:
2042:"Homer regulates gain of ryanodine receptor type 1 channel complex"
4446:
4377:
4372:
4367:
4284:
4271:
4266:
4261:
4256:
4251:
4246:
4197:
4190:
4185:
4180:
4175:
4170:
4165:
4160:
4155:
4143:
4138:
4133:
4123:
4118:
4113:
4108:
4023:
3967:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3872:
3867:
3862:
3857:
3852:
3847:
3842:
3823:
3818:
3813:
3808:
3796:
3713:
3708:
3703:
3688:
3626:
3621:
3616:
3607:
3602:
3588:
3583:
3574:
3569:
3564:
3555:
3550:
3541:
3536:
3503:
3498:
3493:
3488:
3479:
3470:
3465:
3460:
3451:
3446:
3441:
3436:
3427:
3422:
3408:
3403:
3398:
3393:
3388:
3383:
3378:
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3279:
3244:
3214:
3209:
3204:
3199:
3170:
3119:
3114:
3109:
3104:
3094:
3089:
3069:
3054:
3049:
2964:
2959:
2954:
2949:
2933:
2913:
2898:
2859:
2854:
2849:
2844:
2752:
2747:
2470:
2465:
2460:
872:
868:
4526:
4521:
4516:
4506:
4501:
4496:
4486:
4481:
4476:
4471:
4466:
4461:
4456:
4441:
4436:
4431:
4426:
4421:
4416:
4355:
4350:
4345:
4340:
4335:
4241:
4229:
4224:
4219:
4150:
4103:
4067:
4062:
4057:
4052:
3779:
3597:
3155:
2492:
2482:
1349:
1240:
77:
4556:
3741:
2987:
2775:
2432:
2385:
2324:
517:
4080:
3978:
3099:
3059:
2320:
1868:
Avila G, Lee EH, Perez CF, Allen PD, Dirksen RT (June 2003).
1960:"FKBP12 binding modulates ryanodine receptor channel gating"
333:
498:
591:
ryanodine-sensitive calcium-release channel activity
4569:
4393:
4282:
4078:
3976:
3952:
3754:
3360:
3265:
3130:
3003:
2870:
2829:
2791:
2503:
2448:
1557:"Entrez Gene: RYR1 ryanodine receptor 1 (skeletal)"
1126:
1101:
1075:
1050:
1402:
1400:
1398:
1381:
1379:
1377:
2299:GeneReviews/NIH/UW entry on Multiminicore Disease
778:regulation of cytosolic calcium ion concentration
280:
179:
2035:
2033:
2031:
853:release of sequestered calcium ion into cytosol
1407:GRCm38: Ensembl release 89: ENSMUSG00000030592
2397:
2336:
8:
1386:GRCh38: Ensembl release 89: ENSG00000196218
4628:United States National Library of Medicine
4566:
4553:
3751:
3738:
3000:
2984:
2788:
2772:
2445:
2429:
2404:
2390:
2382:
2343:
2329:
2321:
883:
672:junctional sarcoplasmic reticulum membrane
533:
395:Skeletal muscle tissue of rectus abdominis
321:
220:
117:
2291:at the U.S. National Library of Medicine
2215:
2174:
2098:
2057:
1975:
1934:
1885:
1844:
1834:
1777:
1695:
1670:Hanson MG, Niswander LA (December 2014).
1603:
1529:
1519:
4626:This article incorporates text from the
1551:
1549:
753:ossification involved in bone maturation
702:integral component of organelle membrane
596:calcium-induced calcium release activity
403:Skeletal muscle tissue of biceps brachii
2358:
1373:
1222:skeletal muscle-type ryanodine receptor
1218:skeletal muscle calcium release channel
551:voltage-gated calcium channel activity
29:
662:integral component of plasma membrane
285:
246:
241:
184:
143:
138:
7:
3770:Calcium-activated chloride channels
2204:The Journal of Biological Chemistry
2163:The Journal of Biological Chemistry
2087:The Journal of Biological Chemistry
2046:The Journal of Biological Chemistry
1964:The Journal of Biological Chemistry
1874:The Journal of Biological Chemistry
813:calcium ion transmembrane transport
453:medial head of gastrocnemius muscle
2840:Amiloride-sensitive cation channel
1295:, minicore myopathy with external
1236:. In humans, it is encoded by the
1123:
1098:
1072:
1047:
1023:
1004:
978:
959:
933:
914:
798:multicellular organism development
503:
421:
359:
338:
25:
2157:Guo W, Campbell KP (April 1995).
808:skeletal muscle fiber development
27:Protein and coding gene in humans
2361:
848:cellular response to calcium ion
788:cellular calcium ion homeostasis
758:regulation of cardiac conduction
586:calcium-release channel activity
507:
457:extensor digitorum longus muscle
269:
262:
256:
233:
168:
161:
155:
130:
38:
4363:Voltage-dependent anion channel
2456:Inositol trisphosphate receptor
1676:Journal of Neuroscience Methods
712:sarcoplasmic reticulum membrane
4385:General bacterial porin family
1688:10.1016/j.jneumeth.2014.09.013
1263:. RYR1 is associated with the
637:integral component of membrane
518:More reference expression data
487:More reference expression data
1:
2014:10.1016/S0143-4160(03)00082-4
838:cellular response to caffeine
254:
153:
4648:Genes on human chromosome 19
722:cytoplasmic vesicle membrane
682:smooth endoplasmic reticulum
843:protein homotetramerization
803:ion transmembrane transport
783:outflow tract morphogenesis
692:junctional membrane complex
4674:
3804:Chloride Channel Accessory
2413:Membrane transport protein
727:protein-containing complex
707:ryanodine receptor complex
469:sternocleidomastoid muscle
4610:
4565:
4552:
3750:
3737:
2999:
2983:
2799:Epithelial sodium channel
2787:
2771:
2444:
2428:
2356:
2258:10.1016/j.nmd.2005.06.008
1734:10.1007/s00401-012-1007-3
1641:10.1007/s00424-015-1738-9
1442:"Mouse PubMed Reference:"
1424:"Human PubMed Reference:"
1287:gene are associated with
1196:
1191:
1187:
1180:
1164:
1145:
1130:
1105:
1094:
1079:
1054:
1043:
1030:
1026:
1011:
1007:
998:
985:
981:
966:
962:
953:
940:
936:
921:
917:
908:
893:
886:
882:
866:
536:
532:
515:
506:
497:
484:
433:
424:
371:
362:
332:
324:
320:
303:
290:
253:
232:
223:
219:
202:
189:
152:
129:
120:
116:
71:
68:
58:
51:
46:
37:
32:
2716:Cation channels of sperm
2309:RYR1 Variation Database
2293:Medical Subject Headings
2217:10.1074/jbc.274.18.12278
1265:dihydropyridine receptor
556:calcium channel activity
399:tibialis anterior muscle
2246:Neuromuscular Disorders
2176:10.1074/jbc.270.16.9027
1915:The Biochemical Journal
1836:10.1073/pnas.0813010106
1481:10.1126/science.1862346
1315:RYR1 has been shown to
1255:release channel in the
1151:Chr 19: 38.43 – 38.6 Mb
833:transmembrane transport
732:calcium channel complex
441:vastus lateralis muscle
391:vastus lateralis muscle
2100:10.1074/jbc.M312446200
2059:10.1074/jbc.M207675200
1977:10.1074/jbc.M100856200
1887:10.1074/jbc.M205866200
1289:malignant hyperthermia
1257:sarcoplasmic reticulum
667:sarcoplasmic reticulum
437:triceps brachii muscle
387:triceps brachii muscle
2792:Constitutively active
1722:Acta Neuropathologica
1279:Clinical significance
1224:is one of a class of
823:calcium ion transport
697:extracellular exosome
146:Chromosome 19 (human)
1531:10.1093/brain/awl077
1293:central core disease
1251:RYR1 functions as a
1210:Ryanodine receptor 1
1158:Chr 7: 29 – 29.13 Mb
818:response to caffeine
571:ion channel activity
449:gastrocnemius muscle
379:gastrocnemius muscle
287:7 B1|7 16.94 cM
248:Chromosome 7 (mouse)
4559:By gating mechanism
2289:RYR1+protein,+human
1827:2009PNAS..106.6128C
1588:2016NatSR...624450F
1473:1991Sci...253..448F
1232:found primarily in
1226:ryanodine receptors
763:response to hypoxia
601:calcium ion binding
4658:Muscle stabilizers
4630:, which is in the
4086:TRP cation channel
3984:CNG cation channel
3267:Tandem pore domain
2478:Ryanodine receptor
2314:2012-03-01 at the
1576:Scientific Reports
1363:Ryanodine receptor
988:ENSMUSG00000030592
768:muscle contraction
746:Biological process
625:Cellular component
606:nucleotide binding
561:calmodulin binding
544:Molecular function
411:thoracic diaphragm
4622:
4621:
4606:
4605:
4602:
4601:
4594:Stretch-activated
4571:Ion channel class
4548:
4547:
4544:
4543:
3733:
3732:
3729:
3728:
3005:Calcium-activated
2993:Potassium channel
2979:
2978:
2975:
2974:
2767:
2766:
2763:
2762:
2379:
2378:
2136:10.1021/bi981306+
1927:10.1042/bj3540413
1788:10.1021/bi048246u
1596:10.1038/srep24450
1514:(Pt 6): 1470–80.
1283:Mutations in the
1261:transverse tubule
1207:
1206:
1203:
1202:
1176:
1175:
1141:
1140:
1120:
1119:
1090:
1089:
1069:
1068:
1039:
1038:
1020:
1019:
994:
993:
975:
974:
949:
948:
930:
929:
878:
877:
677:terminal cisterna
616:metal ion binding
528:
527:
524:
523:
493:
492:
480:
479:
418:
417:
316:
315:
215:
214:
16:(Redirected from
4665:
4567:
4554:
3762:Chloride channel
3752:
3739:
3132:Inward-rectifier
3001:
2985:
2789:
2773:
2743:Two-pore channel
2446:
2430:
2406:
2399:
2392:
2383:
2365:
2345:
2338:
2331:
2322:
2277:
2252:(9–10): 577–87.
2230:
2229:
2219:
2210:(18): 12278–83.
2195:
2189:
2188:
2178:
2154:
2148:
2147:
2119:
2113:
2112:
2102:
2093:(8): 6994–7000.
2078:
2072:
2071:
2061:
2052:(47): 44722–30.
2037:
2026:
2025:
1996:
1990:
1989:
1979:
1955:
1949:
1948:
1938:
1921:(Pt 2): 413–22.
1906:
1900:
1899:
1889:
1865:
1859:
1858:
1848:
1838:
1806:
1800:
1799:
1781:
1760:
1754:
1753:
1716:
1710:
1709:
1699:
1667:
1661:
1660:
1624:
1618:
1617:
1607:
1567:
1561:
1560:
1553:
1544:
1543:
1533:
1523:
1499:
1493:
1492:
1467:(5018): 448–51.
1456:
1450:
1449:
1438:
1432:
1431:
1420:
1414:
1404:
1393:
1383:
1291:susceptibility,
1216:) also known as
1189:
1188:
1160:
1153:
1136:
1124:
1115:
1099:
1095:RefSeq (protein)
1085:
1073:
1064:
1048:
1024:
1005:
979:
960:
934:
915:
884:
828:skin development
566:protease binding
534:
520:
511:
504:
489:
465:digastric muscle
461:plantaris muscle
429:
427:Top expressed in
422:
367:
365:Top expressed in
360:
339:
322:
312:
299:
288:
273:
266:
260:
249:
237:
221:
211:
198:
187:
172:
165:
159:
148:
134:
118:
112:
110:RYR1 - orthologs
63:
56:
42:
30:
21:
4673:
4672:
4668:
4667:
4666:
4664:
4663:
4662:
4638:
4637:
4623:
4618:
4598:
4561:
4540:
4389:
4288:
4278:
4074:
3972:
3948:
3746:
3725:
3639:
3516:
3373:
3356:
3261:
3225:
3195:
3151:
3143:
3126:
3080:
2995:
2971:
2944:
2883:
2866:
2825:
2783:
2759:
2642:
2614:
2601:
2588:
2568:
2555:
2520:
2499:
2440:
2438:Calcium channel
2424:
2410:
2380:
2375:
2372:
2366:
2352:
2349:
2316:Wayback Machine
2285:
2280:
2242:
2238:
2236:Further reading
2233:
2197:
2196:
2192:
2169:(16): 9027–30.
2156:
2155:
2151:
2121:
2120:
2116:
2080:
2079:
2075:
2039:
2038:
2029:
1998:
1997:
1993:
1970:(20): 16931–5.
1957:
1956:
1952:
1908:
1907:
1903:
1880:(25): 22600–8.
1867:
1866:
1862:
1821:(15): 6128–33.
1808:
1807:
1803:
1779:10.1.1.578.9139
1762:
1761:
1757:
1718:
1717:
1713:
1669:
1668:
1664:
1629:Pflügers Archiv
1626:
1625:
1621:
1569:
1568:
1564:
1555:
1554:
1547:
1521:10.1.1.328.2103
1501:
1500:
1496:
1458:
1457:
1453:
1440:
1439:
1435:
1422:
1421:
1417:
1405:
1396:
1384:
1375:
1371:
1359:
1313:
1297:ophthalmoplegia
1281:
1249:
1234:skeletal muscle
1198:View/Edit Mouse
1193:View/Edit Human
1156:
1149:
1146:Location (UCSC)
1132:
1111:
1107:
1081:
1060:
1056:
969:ENSG00000196218
862:
741:
657:plasma membrane
620:
576:protein binding
516:
485:
476:
473:muscle of thigh
471:
467:
463:
459:
455:
451:
447:
445:temporal muscle
443:
439:
425:
414:
409:
405:
401:
397:
393:
389:
385:
383:muscle of thigh
381:
377:
363:
307:
294:
286:
276:
275:
274:
267:
247:
224:Gene location (
206:
193:
185:
175:
174:
173:
166:
144:
121:Gene location (
72:
59:
52:
28:
23:
22:
15:
12:
11:
5:
4671:
4669:
4661:
4660:
4655:
4650:
4640:
4639:
4620:
4619:
4611:
4608:
4607:
4604:
4603:
4600:
4599:
4597:
4596:
4591:
4586:
4581:
4575:
4573:
4563:
4562:
4557:
4550:
4549:
4546:
4545:
4542:
4541:
4539:
4538:
4533:
4532:
4531:
4530:
4529:
4524:
4519:
4511:
4510:
4509:
4504:
4499:
4491:
4490:
4489:
4484:
4479:
4474:
4469:
4464:
4459:
4451:
4450:
4449:
4444:
4439:
4434:
4429:
4424:
4419:
4405:
4403:
4391:
4390:
4388:
4387:
4382:
4381:
4380:
4375:
4370:
4360:
4359:
4358:
4353:
4348:
4343:
4338:
4333:
4328:
4323:
4318:
4313:
4302:
4300:
4286:
4280:
4279:
4277:
4276:
4275:
4274:
4269:
4264:
4259:
4254:
4249:
4239:
4238:
4237:
4232:
4222:
4217:
4216:
4215:
4210:
4205:
4195:
4194:
4193:
4188:
4183:
4178:
4173:
4168:
4163:
4158:
4148:
4147:
4146:
4141:
4136:
4131:
4126:
4121:
4116:
4111:
4101:
4090:
4088:
4076:
4075:
4073:
4072:
4071:
4070:
4065:
4060:
4055:
4050:
4038:
4037:
4036:
4031:
4026:
4016:
4015:
4014:
4009:
4004:
3999:
3988:
3986:
3974:
3973:
3971:
3970:
3964:
3962:
3960:Proton channel
3950:
3949:
3947:
3946:
3945:
3944:
3939:
3929:
3928:
3927:
3922:
3917:
3912:
3907:
3902:
3897:
3887:
3886:
3885:
3880:
3875:
3870:
3865:
3860:
3855:
3850:
3845:
3835:
3830:
3829:
3828:
3827:
3826:
3821:
3816:
3811:
3801:
3800:
3799:
3794:
3784:
3783:
3782:
3766:
3764:
3748:
3747:
3742:
3735:
3734:
3731:
3730:
3727:
3726:
3724:
3723:
3718:
3717:
3716:
3711:
3706:
3696:
3691:
3686:
3685:
3684:
3679:
3674:
3669:
3659:
3658:
3657:
3652:
3647:
3637:
3632:
3631:
3630:
3629:
3624:
3619:
3612:
3611:
3610:
3605:
3600:
3593:
3592:
3591:
3586:
3579:
3578:
3577:
3572:
3567:
3560:
3559:
3558:
3553:
3546:
3545:
3544:
3539:
3534:
3529:
3524:
3514:
3509:
3508:
3507:
3506:
3501:
3496:
3491:
3484:
3483:
3482:
3475:
3474:
3473:
3468:
3463:
3456:
3455:
3454:
3449:
3444:
3439:
3432:
3431:
3430:
3425:
3418:
3417:
3416:
3411:
3406:
3401:
3396:
3391:
3386:
3381:
3371:
3366:
3364:
3358:
3357:
3355:
3354:
3353:
3352:
3347:
3342:
3337:
3332:
3327:
3322:
3317:
3312:
3307:
3302:
3297:
3292:
3287:
3282:
3271:
3269:
3263:
3262:
3260:
3259:
3258:
3257:
3252:
3247:
3242:
3237:
3232:
3223:
3219:
3218:
3217:
3212:
3207:
3202:
3193:
3185:
3184:
3183:
3178:
3173:
3168:
3163:
3158:
3149:
3145:
3141:
3136:
3134:
3128:
3127:
3125:
3124:
3123:
3122:
3117:
3112:
3107:
3102:
3097:
3092:
3087:
3078:
3074:
3073:
3072:
3064:
3063:
3062:
3057:
3052:
3042:
3041:
3040:
3035:
3030:
3025:
3020:
3009:
3007:
2997:
2996:
2988:
2981:
2980:
2977:
2976:
2973:
2972:
2970:
2969:
2968:
2967:
2962:
2957:
2952:
2942:
2938:
2937:
2936:
2931:
2926:
2921:
2916:
2911:
2906:
2901:
2896:
2891:
2881:
2876:
2874:
2868:
2867:
2865:
2864:
2863:
2862:
2857:
2852:
2847:
2836:
2834:
2827:
2826:
2824:
2823:
2822:
2821:
2816:
2811:
2806:
2795:
2793:
2785:
2784:
2781:Sodium channel
2776:
2769:
2768:
2765:
2764:
2761:
2760:
2758:
2757:
2756:
2755:
2750:
2740:
2739:
2738:
2733:
2728:
2723:
2712:
2711:
2710:
2709:
2704:
2699:
2694:
2684:
2683:
2682:
2677:
2672:
2667:
2657:
2656:
2655:
2650:
2640:
2635:
2634:
2633:
2632:
2627:
2622:
2612:
2604:
2599:
2591:
2586:
2578:
2577:
2576:
2566:
2558:
2553:
2545:
2544:
2543:
2538:
2533:
2528:
2518:
2509:
2507:
2501:
2500:
2498:
2497:
2496:
2495:
2490:
2485:
2475:
2474:
2473:
2468:
2463:
2452:
2450:
2442:
2441:
2433:
2426:
2425:
2411:
2409:
2408:
2401:
2394:
2386:
2377:
2376:
2374:
2373:
2367:
2360:
2357:
2354:
2353:
2350:
2348:
2347:
2340:
2333:
2325:
2319:
2318:
2306:
2301:
2296:
2284:
2283:External links
2281:
2279:
2278:
2239:
2237:
2234:
2232:
2231:
2190:
2149:
2114:
2073:
2027:
1991:
1950:
1901:
1860:
1801:
1755:
1711:
1662:
1619:
1562:
1545:
1494:
1451:
1433:
1415:
1394:
1372:
1370:
1367:
1366:
1365:
1358:
1355:
1354:
1353:
1347:
1341:
1336:
1331:
1326:
1312:
1309:
1280:
1277:
1248:
1245:
1205:
1204:
1201:
1200:
1195:
1185:
1184:
1178:
1177:
1174:
1173:
1171:
1169:
1162:
1161:
1154:
1147:
1143:
1142:
1139:
1138:
1128:
1127:
1121:
1118:
1117:
1103:
1102:
1096:
1092:
1091:
1088:
1087:
1077:
1076:
1070:
1067:
1066:
1052:
1051:
1045:
1041:
1040:
1037:
1036:
1028:
1027:
1021:
1018:
1017:
1009:
1008:
1002:
996:
995:
992:
991:
983:
982:
976:
973:
972:
964:
963:
957:
951:
950:
947:
946:
938:
937:
931:
928:
927:
919:
918:
912:
906:
905:
900:
895:
891:
890:
880:
879:
876:
875:
864:
863:
861:
860:
855:
850:
845:
840:
835:
830:
825:
820:
815:
810:
805:
800:
795:
790:
785:
780:
775:
770:
765:
760:
755:
749:
747:
743:
742:
740:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
674:
669:
664:
659:
654:
649:
644:
639:
634:
628:
626:
622:
621:
619:
618:
613:
608:
603:
598:
593:
588:
583:
581:enzyme binding
578:
573:
568:
563:
558:
553:
547:
545:
541:
540:
530:
529:
526:
525:
522:
521:
513:
512:
501:
495:
494:
491:
490:
482:
481:
478:
477:
475:
474:
470:
466:
462:
458:
454:
450:
446:
442:
438:
434:
431:
430:
419:
416:
415:
413:
412:
408:
407:deltoid muscle
404:
400:
396:
392:
388:
384:
380:
376:
372:
369:
368:
356:
355:
347:
336:
330:
329:
326:RNA expression
318:
317:
314:
313:
305:
301:
300:
292:
289:
284:
278:
277:
268:
261:
255:
251:
250:
245:
239:
238:
230:
229:
217:
216:
213:
212:
204:
200:
199:
191:
188:
183:
177:
176:
167:
160:
154:
150:
149:
142:
136:
135:
127:
126:
114:
113:
70:
66:
65:
57:
49:
48:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4670:
4659:
4656:
4654:
4651:
4649:
4646:
4645:
4643:
4636:
4635:
4633:
4632:public domain
4629:
4617:
4616:
4609:
4595:
4592:
4590:
4589:Voltage-gated
4587:
4585:
4582:
4580:
4577:
4576:
4574:
4572:
4568:
4564:
4560:
4555:
4551:
4537:
4534:
4528:
4525:
4523:
4520:
4518:
4515:
4514:
4512:
4508:
4505:
4503:
4500:
4498:
4495:
4494:
4492:
4488:
4485:
4483:
4480:
4478:
4475:
4473:
4470:
4468:
4465:
4463:
4460:
4458:
4455:
4454:
4452:
4448:
4445:
4443:
4440:
4438:
4435:
4433:
4430:
4428:
4425:
4423:
4420:
4418:
4415:
4414:
4412:
4411:
4410:
4407:
4406:
4404:
4402:
4399:
4397:
4392:
4386:
4383:
4379:
4376:
4374:
4371:
4369:
4366:
4365:
4364:
4361:
4357:
4354:
4352:
4349:
4347:
4344:
4342:
4339:
4337:
4334:
4332:
4329:
4327:
4324:
4322:
4319:
4317:
4314:
4312:
4309:
4308:
4307:
4304:
4303:
4301:
4299:
4296:
4294:
4290:
4281:
4273:
4270:
4268:
4265:
4263:
4260:
4258:
4255:
4253:
4250:
4248:
4245:
4244:
4243:
4240:
4236:
4233:
4231:
4228:
4227:
4226:
4223:
4221:
4218:
4214:
4211:
4209:
4206:
4204:
4201:
4200:
4199:
4196:
4192:
4189:
4187:
4184:
4182:
4179:
4177:
4174:
4172:
4169:
4167:
4164:
4162:
4159:
4157:
4154:
4153:
4152:
4149:
4145:
4142:
4140:
4137:
4135:
4132:
4130:
4127:
4125:
4122:
4120:
4117:
4115:
4112:
4110:
4107:
4106:
4105:
4102:
4099:
4095:
4092:
4091:
4089:
4087:
4084:
4082:
4077:
4069:
4066:
4064:
4061:
4059:
4056:
4054:
4051:
4049:
4046:
4045:
4044:
4043:
4039:
4035:
4032:
4030:
4027:
4025:
4022:
4021:
4020:
4017:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3994:
3993:
3990:
3989:
3987:
3985:
3982:
3980:
3975:
3969:
3966:
3965:
3963:
3961:
3958:
3956:
3951:
3943:
3940:
3938:
3935:
3934:
3933:
3930:
3926:
3923:
3921:
3918:
3916:
3913:
3911:
3908:
3906:
3903:
3901:
3898:
3896:
3893:
3892:
3891:
3888:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3840:
3839:
3836:
3834:
3831:
3825:
3822:
3820:
3817:
3815:
3812:
3810:
3807:
3806:
3805:
3802:
3798:
3795:
3793:
3790:
3789:
3788:
3785:
3781:
3778:
3777:
3776:
3773:
3772:
3771:
3768:
3767:
3765:
3763:
3760:
3758:
3753:
3749:
3745:
3744:Miscellaneous
3740:
3736:
3722:
3721:Shaker (gene)
3719:
3715:
3712:
3710:
3707:
3705:
3702:
3701:
3700:
3697:
3695:
3694:minK/ISK-like
3692:
3690:
3687:
3683:
3680:
3678:
3675:
3673:
3670:
3668:
3665:
3664:
3663:
3660:
3656:
3653:
3651:
3648:
3646:
3643:
3642:
3641:
3634:
3633:
3628:
3625:
3623:
3620:
3618:
3615:
3614:
3613:
3609:
3606:
3604:
3601:
3599:
3596:
3595:
3594:
3590:
3587:
3585:
3582:
3581:
3580:
3576:
3573:
3571:
3568:
3566:
3563:
3562:
3561:
3557:
3554:
3552:
3549:
3548:
3547:
3543:
3540:
3538:
3535:
3533:
3530:
3528:
3525:
3523:
3520:
3519:
3518:
3511:
3510:
3505:
3502:
3500:
3497:
3495:
3492:
3490:
3487:
3486:
3485:
3481:
3478:
3477:
3476:
3472:
3469:
3467:
3464:
3462:
3459:
3458:
3457:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3434:
3433:
3429:
3426:
3424:
3421:
3420:
3419:
3415:
3412:
3410:
3407:
3405:
3402:
3400:
3397:
3395:
3392:
3390:
3387:
3385:
3382:
3380:
3377:
3376:
3375:
3368:
3367:
3365:
3363:
3362:Voltage-gated
3359:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3326:
3323:
3321:
3318:
3316:
3313:
3311:
3308:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3288:
3286:
3283:
3281:
3278:
3277:
3276:
3273:
3272:
3270:
3268:
3264:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3236:
3233:
3231:
3228:
3227:
3226:
3220:
3216:
3213:
3211:
3208:
3206:
3203:
3201:
3198:
3197:
3196:
3189:
3186:
3182:
3179:
3177:
3174:
3172:
3169:
3167:
3164:
3162:
3159:
3157:
3154:
3153:
3152:
3146:
3144:
3138:
3137:
3135:
3133:
3129:
3121:
3118:
3116:
3113:
3111:
3108:
3106:
3103:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3082:
3081:
3075:
3071:
3068:
3067:
3065:
3061:
3058:
3056:
3053:
3051:
3048:
3047:
3046:
3043:
3039:
3036:
3034:
3031:
3029:
3026:
3024:
3021:
3019:
3016:
3015:
3014:
3011:
3010:
3008:
3006:
3002:
2998:
2994:
2991:
2986:
2982:
2966:
2963:
2961:
2958:
2956:
2953:
2951:
2948:
2947:
2946:
2939:
2935:
2932:
2930:
2927:
2925:
2922:
2920:
2917:
2915:
2912:
2910:
2907:
2905:
2902:
2900:
2897:
2895:
2892:
2890:
2887:
2886:
2885:
2878:
2877:
2875:
2873:
2872:Voltage-gated
2869:
2861:
2858:
2856:
2853:
2851:
2848:
2846:
2843:
2842:
2841:
2838:
2837:
2835:
2832:
2828:
2820:
2817:
2815:
2812:
2810:
2807:
2805:
2802:
2801:
2800:
2797:
2796:
2794:
2790:
2786:
2782:
2779:
2774:
2770:
2754:
2751:
2749:
2746:
2745:
2744:
2741:
2737:
2734:
2732:
2729:
2727:
2724:
2722:
2719:
2718:
2717:
2714:
2713:
2708:
2705:
2703:
2700:
2698:
2695:
2693:
2690:
2689:
2688:
2685:
2681:
2678:
2676:
2673:
2671:
2668:
2666:
2663:
2662:
2661:
2658:
2654:
2651:
2649:
2646:
2645:
2644:
2637:
2636:
2631:
2628:
2626:
2623:
2621:
2618:
2617:
2616:
2608:
2605:
2603:
2595:
2592:
2590:
2582:
2579:
2575:
2572:
2571:
2570:
2562:
2559:
2557:
2549:
2546:
2542:
2539:
2537:
2534:
2532:
2529:
2527:
2524:
2523:
2522:
2514:
2511:
2510:
2508:
2506:
2505:Voltage-gated
2502:
2494:
2491:
2489:
2486:
2484:
2481:
2480:
2479:
2476:
2472:
2469:
2467:
2464:
2462:
2459:
2458:
2457:
2454:
2453:
2451:
2447:
2443:
2439:
2436:
2431:
2427:
2422:
2418:
2414:
2407:
2402:
2400:
2395:
2393:
2388:
2387:
2384:
2370:
2364:
2359:
2355:
2346:
2341:
2339:
2334:
2332:
2327:
2326:
2323:
2317:
2313:
2310:
2307:
2305:
2302:
2300:
2297:
2294:
2290:
2287:
2286:
2282:
2275:
2271:
2267:
2263:
2259:
2255:
2251:
2247:
2241:
2240:
2235:
2227:
2223:
2218:
2213:
2209:
2205:
2201:
2194:
2191:
2186:
2182:
2177:
2172:
2168:
2164:
2160:
2153:
2150:
2145:
2141:
2137:
2133:
2129:
2125:
2118:
2115:
2110:
2106:
2101:
2096:
2092:
2088:
2084:
2077:
2074:
2069:
2065:
2060:
2055:
2051:
2047:
2043:
2036:
2034:
2032:
2028:
2023:
2019:
2015:
2011:
2008:(2): 177–84.
2007:
2003:
1995:
1992:
1987:
1983:
1978:
1973:
1969:
1965:
1961:
1954:
1951:
1946:
1942:
1937:
1932:
1928:
1924:
1920:
1916:
1912:
1905:
1902:
1897:
1893:
1888:
1883:
1879:
1875:
1871:
1864:
1861:
1856:
1852:
1847:
1842:
1837:
1832:
1828:
1824:
1820:
1816:
1812:
1805:
1802:
1797:
1793:
1789:
1785:
1780:
1775:
1772:(1): 278–84.
1771:
1767:
1759:
1756:
1751:
1747:
1743:
1739:
1735:
1731:
1728:(4): 575–81.
1727:
1723:
1715:
1712:
1707:
1703:
1698:
1693:
1689:
1685:
1681:
1677:
1673:
1666:
1663:
1658:
1654:
1650:
1646:
1642:
1638:
1635:(2): 269–78.
1634:
1630:
1623:
1620:
1615:
1611:
1606:
1601:
1597:
1593:
1589:
1585:
1581:
1577:
1573:
1566:
1563:
1558:
1552:
1550:
1546:
1541:
1537:
1532:
1527:
1522:
1517:
1513:
1509:
1505:
1498:
1495:
1490:
1486:
1482:
1478:
1474:
1470:
1466:
1462:
1455:
1452:
1447:
1443:
1437:
1434:
1429:
1425:
1419:
1416:
1412:
1408:
1403:
1401:
1399:
1395:
1391:
1387:
1382:
1380:
1378:
1374:
1368:
1364:
1361:
1360:
1356:
1351:
1348:
1345:
1342:
1340:
1337:
1335:
1332:
1330:
1327:
1325:
1322:
1321:
1320:
1318:
1310:
1308:
1306:
1302:
1298:
1294:
1290:
1286:
1278:
1276:
1272:
1268:
1266:
1262:
1258:
1254:
1246:
1244:
1242:
1239:
1235:
1231:
1227:
1223:
1219:
1215:
1211:
1199:
1194:
1190:
1186:
1183:
1179:
1172:
1170:
1167:
1163:
1159:
1155:
1152:
1148:
1144:
1137:
1135:
1129:
1125:
1122:
1116:
1114:
1110:
1104:
1100:
1097:
1093:
1086:
1084:
1078:
1074:
1071:
1065:
1063:
1059:
1053:
1049:
1046:
1044:RefSeq (mRNA)
1042:
1035:
1034:
1029:
1025:
1022:
1016:
1015:
1010:
1006:
1003:
1001:
997:
990:
989:
984:
980:
977:
971:
970:
965:
961:
958:
956:
952:
945:
944:
939:
935:
932:
926:
925:
920:
916:
913:
911:
907:
904:
901:
899:
896:
892:
889:
885:
881:
874:
870:
865:
859:
856:
854:
851:
849:
846:
844:
841:
839:
836:
834:
831:
829:
826:
824:
821:
819:
816:
814:
811:
809:
806:
804:
801:
799:
796:
794:
793:ion transport
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
754:
751:
750:
748:
745:
744:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
629:
627:
624:
623:
617:
614:
612:
609:
607:
604:
602:
599:
597:
594:
592:
589:
587:
584:
582:
579:
577:
574:
572:
569:
567:
564:
562:
559:
557:
554:
552:
549:
548:
546:
543:
542:
539:
538:Gene ontology
535:
531:
519:
514:
510:
505:
502:
500:
496:
488:
483:
472:
468:
464:
460:
456:
452:
448:
444:
440:
436:
435:
432:
428:
423:
420:
410:
406:
402:
398:
394:
390:
386:
382:
378:
374:
373:
370:
366:
361:
358:
357:
354:
352:
348:
346:
345:
341:
340:
337:
335:
331:
327:
323:
319:
311:
306:
302:
298:
293:
283:
279:
272:
265:
259:
252:
244:
240:
236:
231:
227:
222:
218:
210:
205:
201:
197:
192:
182:
178:
171:
164:
158:
151:
147:
141:
137:
133:
128:
124:
119:
115:
111:
107:
103:
99:
95:
91:
87:
83:
79:
75:
67:
62:
55:
50:
45:
41:
36:
31:
19:
4653:Ion channels
4625:
4624:
4612:
4579:Ligand-gated
4570:
4558:
4401:Gap junction
4394:
4283:
4079:
4040:
4018:
3991:
3977:
3953:
3931:
3889:
3837:
3803:
3786:
3774:
3755:
3743:
3698:
3661:
3635:
3512:
3369:
3274:
3221:
3191:
3147:
3076:
2989:
2940:
2879:
2777:
2686:
2659:
2638:
2610:
2597:
2584:
2564:
2551:
2516:
2449:Ligand-gated
2434:
2417:ion channels
2368:
2249:
2245:
2207:
2203:
2193:
2166:
2162:
2152:
2127:
2124:Biochemistry
2123:
2117:
2090:
2086:
2076:
2049:
2045:
2005:
2002:Cell Calcium
2001:
1994:
1967:
1963:
1953:
1918:
1914:
1904:
1877:
1873:
1863:
1818:
1814:
1804:
1769:
1766:Biochemistry
1765:
1758:
1725:
1721:
1714:
1679:
1675:
1665:
1632:
1628:
1622:
1579:
1575:
1565:
1511:
1507:
1497:
1464:
1460:
1454:
1445:
1436:
1427:
1418:
1314:
1311:Interactions
1284:
1282:
1273:
1269:
1250:
1237:
1221:
1217:
1213:
1209:
1208:
1131:
1113:NP_001036188
1106:
1080:
1062:NM_001042723
1055:
1031:
1012:
986:
967:
941:
922:
902:
897:
349:
342:
69:External IDs
4584:Light-gated
3066:IK channel
2351:PDB gallery
2130:(1): 90–7.
687:cell cortex
611:ATP binding
308:29,125,179
295:29,003,344
207:38,595,273
194:38,433,691
47:Identifiers
4642:Categories
3787:Bestrophin
3045:SK channel
3013:BK channel
2687:γ-subunits
2660:β-subunits
2643:δ-subunits
1682:: 95–104.
1413:, May 2017
1392:, May 2017
1369:References
1324:calmodulin
1305:Dantrolene
737:sarcolemma
717:Z discdkac
353:(ortholog)
90:HomoloGene
4615:disorders
4613:see also
4396:Cytoplasm
4306:Aquaporin
3775:Anoctamin
3598:11.1/hERG
1774:CiteSeerX
1582:: 24450.
1516:CiteSeerX
1301:samaritan
1134:NP_033135
1109:NP_000531
1083:NM_009109
1058:NM_000540
888:Orthologs
858:transport
632:cytoplasm
98:GeneCards
4409:Connexin
3689:minK/ISK
2312:Archived
2274:31372661
2266:16084090
2226:10212196
2109:14638677
2068:12223488
2022:12810060
1986:11279144
1945:11171121
1896:12704193
1855:19332786
1796:15628869
1742:22752422
1706:25251554
1649:26438192
1614:27102063
1540:16621918
1409:–
1388:–
1357:See also
1317:interact
1247:Function
1182:Wikidata
867:Sources:
652:T-tubule
642:membrane
4536:Innexin
4293:solutes
2185:7721813
2144:9890886
1936:1221670
1846:2662960
1823:Bibcode
1750:9014320
1697:4252626
1657:5894066
1605:4840354
1584:Bibcode
1489:1862346
1469:Bibcode
1461:Science
1411:Ensembl
1390:Ensembl
1253:calcium
1230:protein
1000:UniProt
955:Ensembl
894:Species
873:QuickGO
328:pattern
186:19q13.2
54:Aliases
2833:-gated
2831:Proton
2607:T-type
2594:R-type
2581:Q-type
2561:P-type
2548:N-type
2513:L-type
2295:(MeSH)
2272:
2264:
2224:
2183:
2142:
2107:
2066:
2020:
1984:
1943:
1933:
1894:
1853:
1843:
1794:
1776:
1748:
1740:
1704:
1694:
1655:
1647:
1612:
1602:
1538:
1518:
1487:
1344:HOMER3
1339:HOMER2
1334:HOMER1
1329:FKBP1A
1319:with:
1228:and a
1168:search
1166:PubMed
1033:E9PZQ0
1014:P21817
910:Entrez
647:I band
499:BioGPS
375:glutes
78:180901
4447:GJA10
4298:Porin
4198:TRPML
3968:HVCN1
3662:KCNIP
3517:α7-12
2421:TC 1A
2270:S2CID
1746:S2CID
1653:S2CID
1508:Brain
1214:RYR-1
943:20190
903:Mouse
898:Human
869:Amigo
351:Mouse
344:Human
291:Start
226:Mouse
190:Start
123:Human
94:68069
86:99659
4527:GJD4
4522:GJD3
4517:GJD2
4507:GJC3
4502:GJC2
4497:GJC1
4487:GJB7
4482:GJB6
4477:GJB5
4472:GJB4
4467:GJB3
4462:GJB2
4457:GJB1
4442:GJA9
4437:GJA8
4432:GJA5
4427:GJA4
4422:GJA3
4417:GJA1
4242:TRPV
4225:TRPP
4220:TRPN
4151:TRPM
4104:TRPC
4094:TRPA
3932:CLNS
3890:CLIC
3838:CLCN
3833:CFTR
3780:ANO1
3699:MiRP
3627:12.3
3622:12.2
3617:12.1
3608:11.3
3603:11.2
3589:10.2
3584:10.1
3374:α1-6
3188:GIRK
2602:α2.3
2589:α2.1
2556:α2.2
2369:2bcx
2262:PMID
2222:PMID
2181:PMID
2140:PMID
2105:PMID
2064:PMID
2018:PMID
1982:PMID
1941:PMID
1892:PMID
1851:PMID
1792:PMID
1738:PMID
1702:PMID
1645:PMID
1610:PMID
1536:PMID
1485:PMID
1350:TRDN
1299:and
1285:RYR1
1241:gene
1238:RYR1
924:6261
334:Bgee
282:Band
243:Chr.
181:Band
140:Chr.
102:RYR1
74:OMIM
61:RYR1
33:RYR1
18:RyR1
4291:(+
4129:4AP
4042:HCN
3575:9.3
3570:9.2
3565:9.1
3556:8.2
3551:8.1
3542:7.5
3537:7.4
3532:7.3
3527:7.2
3522:7.1
3504:6.4
3499:6.3
3494:6.2
3489:6.1
3480:5.1
3471:4.3
3466:4.2
3461:4.1
3452:3.4
3447:3.3
3442:3.2
3437:3.1
3428:2.2
3423:2.1
3414:1.8
3409:1.7
3404:1.6
3399:1.5
3394:1.4
3389:1.3
3384:1.2
3379:1.1
3275:K2P
3255:7.1
3250:6.2
3245:6.1
3240:5.1
3235:4.2
3230:4.1
3215:3.4
3210:3.3
3205:3.2
3200:3.1
3181:2.6
3176:2.4
3171:2.3
3166:2.2
3161:2.1
3156:1.1
3142:ATP
3120:5.1
3115:4.2
3110:4.1
3105:3.1
3100:2.3
3095:2.2
3090:2.1
3085:1.1
3070:IK1
3060:SK3
3055:SK2
3050:SK1
2929:1.9
2924:1.8
2919:1.7
2914:1.6
2909:1.5
2904:1.4
2899:1.3
2894:1.2
2889:1.1
2778:Na:
2630:3.3
2625:3.2
2620:3.1
2574:2.1
2541:1.4
2536:1.3
2531:1.2
2526:1.1
2435:Ca:
2254:doi
2212:doi
2208:274
2171:doi
2167:270
2132:doi
2095:doi
2091:279
2054:doi
2050:277
2010:doi
1972:doi
1968:276
1931:PMC
1923:doi
1919:354
1882:doi
1878:278
1841:PMC
1831:doi
1819:106
1784:doi
1730:doi
1726:124
1692:PMC
1684:doi
1680:238
1637:doi
1633:468
1600:PMC
1592:doi
1526:doi
1512:129
1477:doi
1465:253
1346:and
1220:or
304:End
203:End
106:OMA
82:MGI
4644::
4513:D
4493:C
4453:B
4413:A
4295:):
4048:FC
3942:1B
3937:1A
3925:L1
3883:KB
3878:KA
3757:Cl
3350:18
3345:17
3340:16
3335:15
3330:13
3325:12
3320:10
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