324:
301:
198:
223:
589:
582:
575:
330:
229:
29:
1171:. In yeast the 9-1-1 complex (including RAD1) facilitates meiotic recombination. An alternative, but inaccurate, mechanism for repairing double-strand breaks is non-homologous end joining. In the rice plant, the 9-1-1 complex promotes accurate meiotic recombination by suppressing the alternative process of
1146:
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract
55:
1473:
Pereira C, Arroyo-Martinez GA, Guo MZ, Downey MS, Kelly ER, Grive KJ, Mahadevaiah SK, Sims JR, Faca VM, Tsai C, Schiltz CJ, Wit N, Jacobs H, Clark NL, Freire R, Turner J, Lyndaker AM, Brieno-Enriquez MA, Cohen PE, Smolka MB, Weiss RS (February 2022).
2155:
Dean FB, Lian L, O'Donnell M (1999). "cDNA cloning and gene mapping of human homologs for
Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster".
2083:
Marathi UK, Dahlen M, Sunnerhagen P, Romero AV, Ramagli LS, Siciliano MJ, Li L, Legerski RJ (1999). "RAD1, a human structural homolog of the
Schizosaccharomyces pombe RAD1 cell cycle checkpoint gene".
1720:
Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, Chen SM, Abraham RT, Wang XF (June 2001). "ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses".
2427:
Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, Chen SM, Abraham RT, Wang XF (2001). "ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses".
1960:
Bardwell AJ, Bardwell L, Johnson DK, Friedberg EC (1993). "Yeast DNA recombination and repair proteins Rad1 and Rad10 constitute a complex in vivo mediated by localized hydrophobic domains".
1366:
Bluyssen HA, van Os RI, Naus NC, Jaspers I, Hoeijmakers JH, de Klein A (January 1999). "A human and mouse homolog of the
Schizosaccharomyces pombe rad1+ cell cycle checkpoint control gene".
337:
236:
1147:
specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
1577:
Hang H, Zhang Y, Dunbrack RL, Wang C, Lieberman HB (April 2002). "Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1".
2601:
Hang H, Zhang Y, Dunbrack RL, Wang C, Lieberman HB (2002). "Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1".
837:
145:
1319:"Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis"
818:
2230:"Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression"
1763:
Dufault VM, Oestreich AJ, Vroman BT, Karnitz LM (Dec 2003). "Identification and characterization of RAD9B, a paralog of the RAD9 checkpoint gene".
1299:
1281:
2683:
2560:"Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy"
1800:"Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy"
323:
1072:
1065:
300:
1614:"Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro"
1404:
1268:
1247:
1423:"The Exonuclease Homolog OsRAD1 Promotes Accurate Meiotic Double-Strand Break Repair by Suppressing Nonhomologous End Joining"
1264:
222:
197:
52:
1243:
125:
1199:
2187:"The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1"
336:
235:
1172:
2386:"Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex"
329:
228:
2114:"Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex"
1530:"Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex"
1164:
882:
169:
133:
2466:"The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9"
2465:
2042:"HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene"
2632:"A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex"
1849:"A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex"
1182:. Testis-specific disruption of RAD1 in mice results in defective double-strand break repair, depletion of
863:
2300:"Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage"
1476:"Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis"
1168:
1179:
1612:
Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A (February 2003).
1909:
1625:
211:
2265:"HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins"
112:
2517:"Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin"
2343:"The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9"
1673:"The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9"
1044:
1040:
989:
985:
952:
2661:
2589:
2503:
2452:
2415:
2372:
2329:
2143:
2028:
1999:"A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease"
1985:
1878:
1829:
1745:
1702:
1559:
157:
1048:
1019:
993:
964:
960:
956:
2653:
2618:
2581:
2546:
2495:
2444:
2407:
2364:
2321:
2286:
2251:
2216:
2173:
2135:
2100:
2071:
2020:
1977:
1937:
1870:
1821:
1780:
1737:
1694:
1653:
1594:
1551:
1507:
1452:
1383:
1348:
105:
45:
2643:
2610:
2571:
2536:
2528:
2485:
2477:
2436:
2397:
2354:
2311:
2276:
2241:
2206:
2198:
2165:
2125:
2092:
2061:
2053:
2010:
1969:
1927:
1917:
1860:
1811:
1772:
1729:
1684:
1643:
1633:
1586:
1541:
1497:
1487:
1442:
1434:
1375:
1338:
1330:
588:
581:
574:
416:
347:
291:
246:
175:
391:
153:
1913:
1629:
1997:
Parker AE, Van de Weyer I, Laus MC, Oostveen I, Yon J, Verhasselt P, Luyten WH (1998).
1973:
1502:
1475:
1447:
1422:
28:
2541:
2516:
2066:
2041:
1776:
1648:
1613:
1343:
1318:
1317:
Freire R, Murguía JR, Tarsounas M, Lowndes NF, Moens PB, Jackson SP (September 1998).
752:
747:
742:
737:
732:
727:
722:
717:
712:
696:
691:
686:
681:
676:
660:
655:
650:
645:
640:
635:
630:
2677:
2211:
2186:
1932:
1897:
617:
2665:
2593:
2507:
2419:
2376:
2333:
2147:
2032:
1989:
1882:
1833:
1706:
1563:
137:
2456:
1749:
409:
188:
1167:. Recombination is a process that repairs the breaks and also promotes faithful
161:
1898:"Purification and characterization of human DNA damage checkpoint Rad complexes"
1421:
Hu Q, Tang D, Wang H, Shen Y, Chen X, Ji J, Du G, Li Y, Cheng Z (October 2016).
1304:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1286:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1187:
492:
308:
205:
141:
2057:
2015:
1998:
1638:
1183:
782:
552:
430:
375:
362:
274:
261:
149:
2657:
2648:
2631:
2622:
2614:
2585:
2576:
2559:
2550:
2499:
2481:
2448:
2411:
2402:
2385:
2368:
2359:
2342:
2325:
2316:
2299:
2290:
2281:
2264:
2255:
2246:
2229:
2220:
2169:
2096:
1941:
1922:
1874:
1865:
1848:
1825:
1816:
1799:
1784:
1741:
1698:
1689:
1672:
1657:
1598:
1590:
1511:
1456:
1379:
1334:
2202:
2177:
2139:
2130:
2113:
2104:
2075:
2024:
1981:
1555:
1546:
1529:
1387:
1352:
1112:
1107:
1096:
927:
908:
2384:
Burtelow MA, Roos-Mattjus PM, Rauen M, Babendure JR, Karnitz LM (2001).
1492:
1438:
2532:
2464:
Xiang SL, Kumano T, Iwasaki SI, Sun X, Yoshioka K, Yamamoto KC (2001).
1156:
1128:
894:
849:
82:
78:
74:
2490:
2440:
1896:
Lindsey-Boltz LA, Bermudez VP, Hurwitz J, Sancar A (September 2001).
1733:
1080:
804:
1218:
1212:
767:
763:
1206:
1135:
129:
1671:
Rauen M, Burtelow MA, Dufault VM, Karnitz LM (September 2000).
597:
1160:
1178:
During mammalian meiosis 9-1-1 complexes promote synapsis of
399:
748:
regulation of signal transduction by p53 class mediator
116:, HREC1, RAD1 homolog, RAD1 checkpoint DNA exonuclease
2341:
Rauen M, Burtelow MA, Dufault VM, Karnitz LM (2000).
2263:
Cai RL, Yan-Neale Y, Cueto MA, Xu H, Cohen D (2000).
564:
1798:
Griffith JD, Lindsey-Boltz LA, Sancar A (May 2002).
2185:St Onge RP, Udell CM, Casselman R, Davey S (1999).
1033:
1012:
978:
945:
1260:
1258:
1256:
1239:
1237:
1235:
346:
245:
2558:Griffith JD, Lindsey-Boltz LA, Sancar A (2002).
16:Protein-coding gene in the species Homo sapiens
1523:
1521:
1265:GRCm38: Ensembl release 89: ENSMUSG00000022248
2298:Burtelow MA, Kaufmann SH, Karnitz LM (2000).
1468:
1466:
8:
1405:"Entrez Gene: RAD1 RAD1 homolog (S. pombe)"
1244:GRCh38: Ensembl release 89: ENSG00000113456
743:nucleic acid phosphodiester bond hydrolysis
778:
733:meiotic recombination checkpoint signaling
613:
387:
286:
183:
63:
2647:
2575:
2540:
2489:
2401:
2358:
2315:
2280:
2245:
2210:
2129:
2065:
2014:
1931:
1921:
1864:
1815:
1688:
1647:
1637:
1545:
1501:
1491:
1446:
1342:
1416:
1414:
1399:
1397:
723:cellular response to DNA damage stimulus
677:intracellular membrane-bounded organelle
1231:
738:cellular response to ionizing radiation
1528:Volkmer E, Karnitz LM (January 1999).
18:
351:
312:
307:
250:
209:
204:
7:
2515:Zou L, Cortez D, Elledge SJ (2002).
2040:Udell CM, Lee SK, Davey S (1998).
1974:10.1111/j.1365-2958.1993.tb01662.x
1125:Cell cycle checkpoint protein RAD1
1030:
1009:
975:
942:
918:
899:
873:
854:
828:
809:
569:
487:
425:
404:
14:
1131:that in humans is encoded by the
636:exodeoxyribonuclease III activity
1159:, double-strand breaks occur in
587:
580:
573:
335:
328:
322:
299:
234:
227:
221:
196:
27:
1198:RAD1 homolog has been shown to
718:DNA damage checkpoint signaling
2112:Volkmer E, Karnitz LM (1999).
1847:Hirai I, Wang HG (July 2002).
598:More reference expression data
553:More reference expression data
1:
2470:Biochem. Biophys. Res. Commun
2228:Hang H, Lieberman HB (2000).
1777:10.1016/s0888-7543(03)00200-3
320:
219:
1902:Proc. Natl. Acad. Sci. U.S.A
1618:Proc. Natl. Acad. Sci. U.S.A
713:substantia nigra development
2684:Genes on human chromosome 5
2700:
1173:non-homologous end joining
646:3'-5' exonuclease activity
539:medial ganglionic eminence
461:superior surface of tongue
2630:Hirai I, Wang HG (2002).
1300:"Mouse PubMed Reference:"
1282:"Human PubMed Reference:"
1111:
1106:
1102:
1095:
1079:
1060:
1037:
1016:
1005:
982:
949:
938:
925:
921:
906:
902:
893:
880:
876:
861:
857:
848:
835:
831:
816:
812:
803:
788:
781:
777:
761:
616:
612:
595:
572:
563:
550:
499:
490:
437:
428:
398:
390:
386:
369:
356:
319:
298:
289:
285:
268:
255:
218:
195:
186:
182:
173:
168:
123:
120:
110:
103:
98:
71:
66:
49:
44:
39:
35:
26:
21:
2016:10.1074/jbc.273.29.18332
692:checkpoint clamp complex
1639:10.1073/pnas.0437927100
1073:Chr 15: 10.49 – 10.5 Mb
1066:Chr 5: 34.91 – 34.92 Mb
2649:10.1074/jbc.M203079200
2615:10.1006/geno.2002.6737
2577:10.1074/jbc.C200129200
2482:10.1006/bbrc.2001.5685
2403:10.1074/jbc.M102946200
2360:10.1074/jbc.M005782200
2317:10.1074/jbc.M001244200
2282:10.1074/jbc.M000168200
2247:10.1006/geno.2000.6142
2170:10.1006/geno.1998.5587
2097:10.1006/geno.1998.5589
2058:10.1093/nar/26.17.3971
1923:10.1073/pnas.201373498
1866:10.1074/jbc.M203079200
1817:10.1074/jbc.C200129200
1690:10.1074/jbc.M005782200
1591:10.1006/geno.2002.6737
1380:10.1006/geno.1998.5582
1335:10.1101/gad.12.16.2560
1180:homologous chromosomes
1169:chromosome segregation
465:ventral tegmental area
2203:10.1091/mbc.10.6.1985
2131:10.1074/jbc.274.2.567
1547:10.1074/jbc.274.2.567
314:Chromosome 15 (mouse)
656:exonuclease activity
212:Chromosome 5 (human)
67:List of PDB id codes
40:Available structures
1914:2001PNAS...9811236L
1630:2003PNAS..100.1633B
1493:10.7554/eLife.68677
1439:10.1104/pp.16.00831
631:damaged DNA binding
523:endocardial cushion
2533:10.1101/gad.950302
883:ENSMUSG00000022248
706:Biological process
670:Cellular component
661:hydrolase activity
624:Molecular function
2046:Nucleic Acids Res
1122:
1121:
1118:
1117:
1091:
1090:
1056:
1055:
1027:
1026:
1001:
1000:
972:
971:
934:
933:
915:
914:
889:
888:
870:
869:
844:
843:
825:
824:
773:
772:
651:nuclease activity
608:
607:
604:
603:
559:
558:
546:
545:
484:
483:
382:
381:
281:
280:
94:
93:
90:
89:
50:Ortholog search:
2691:
2669:
2651:
2626:
2597:
2579:
2554:
2544:
2511:
2493:
2460:
2441:10.1038/35082110
2435:(6840): 969–74.
2423:
2405:
2380:
2362:
2353:(38): 29767–71.
2337:
2319:
2294:
2284:
2275:(36): 27909–16.
2259:
2249:
2224:
2214:
2181:
2151:
2133:
2108:
2079:
2069:
2036:
2018:
1993:
1946:
1945:
1935:
1925:
1908:(20): 11236–41.
1893:
1887:
1886:
1868:
1844:
1838:
1837:
1819:
1795:
1789:
1788:
1760:
1754:
1753:
1734:10.1038/35082110
1728:(6840): 969–74.
1717:
1711:
1710:
1692:
1683:(38): 29767–71.
1668:
1662:
1661:
1651:
1641:
1609:
1603:
1602:
1574:
1568:
1567:
1549:
1525:
1516:
1515:
1505:
1495:
1470:
1461:
1460:
1450:
1418:
1409:
1408:
1401:
1392:
1391:
1363:
1357:
1356:
1346:
1314:
1308:
1307:
1296:
1290:
1289:
1278:
1272:
1262:
1251:
1241:
1104:
1103:
1075:
1068:
1051:
1031:
1022:
1010:
1006:RefSeq (protein)
996:
976:
967:
943:
919:
900:
874:
855:
829:
810:
779:
614:
600:
591:
584:
577:
570:
555:
515:ventricular zone
495:
493:Top expressed in
488:
441:secondary oocyte
433:
431:Top expressed in
426:
405:
388:
378:
365:
354:
339:
332:
326:
315:
303:
287:
277:
264:
253:
238:
231:
225:
214:
200:
184:
178:
164:
162:RAD1 - orthologs
115:
108:
85:
64:
58:
37:
36:
31:
19:
2699:
2698:
2694:
2693:
2692:
2690:
2689:
2688:
2674:
2673:
2672:
2642:(28): 25722–7.
2629:
2600:
2570:(18): 15233–6.
2557:
2514:
2463:
2426:
2396:(28): 25903–9.
2383:
2340:
2310:(34): 26343–8.
2297:
2262:
2227:
2191:Mol. Biol. Cell
2184:
2154:
2111:
2082:
2039:
2009:(29): 18332–9.
1996:
1959:
1955:
1953:Further reading
1950:
1949:
1895:
1894:
1890:
1859:(28): 25722–7.
1846:
1845:
1841:
1810:(18): 15233–6.
1797:
1796:
1792:
1762:
1761:
1757:
1719:
1718:
1714:
1670:
1669:
1665:
1611:
1610:
1606:
1576:
1575:
1571:
1527:
1526:
1519:
1472:
1471:
1464:
1420:
1419:
1412:
1403:
1402:
1395:
1365:
1364:
1360:
1329:(16): 2560–73.
1316:
1315:
1311:
1298:
1297:
1293:
1280:
1279:
1275:
1263:
1254:
1242:
1233:
1228:
1196:
1153:
1144:
1113:View/Edit Mouse
1108:View/Edit Human
1071:
1064:
1061:Location (UCSC)
1047:
1043:
1039:
1018:
992:
988:
984:
963:
959:
955:
951:
864:ENSG00000113456
757:
728:DNA replication
701:
665:
641:protein binding
596:
586:
585:
579:
578:
551:
542:
537:
533:
529:
525:
521:
517:
513:
509:
505:
491:
480:
477:Achilles tendon
475:
471:
467:
463:
459:
455:
453:visceral pleura
451:
447:
443:
429:
373:
360:
352:
342:
341:
340:
333:
313:
290:Gene location (
272:
259:
251:
241:
240:
239:
232:
210:
187:Gene location (
174:
124:
111:
104:
73:
51:
17:
12:
11:
5:
2697:
2695:
2687:
2686:
2676:
2675:
2671:
2670:
2627:
2598:
2555:
2527:(2): 198–208.
2512:
2461:
2424:
2381:
2338:
2295:
2260:
2225:
2197:(6): 1985–95.
2182:
2152:
2109:
2080:
2052:(17): 3971–6.
2037:
1994:
1968:(6): 1177–88.
1962:Mol. Microbiol
1956:
1954:
1951:
1948:
1947:
1888:
1839:
1790:
1755:
1712:
1663:
1604:
1569:
1517:
1462:
1433:(2): 1105–16.
1410:
1393:
1358:
1309:
1291:
1273:
1252:
1230:
1229:
1227:
1224:
1223:
1222:
1216:
1210:
1195:
1192:
1163:that initiate
1152:
1149:
1143:
1140:
1120:
1119:
1116:
1115:
1110:
1100:
1099:
1093:
1092:
1089:
1088:
1086:
1084:
1077:
1076:
1069:
1062:
1058:
1057:
1054:
1053:
1035:
1034:
1028:
1025:
1024:
1014:
1013:
1007:
1003:
1002:
999:
998:
980:
979:
973:
970:
969:
947:
946:
940:
936:
935:
932:
931:
923:
922:
916:
913:
912:
904:
903:
897:
891:
890:
887:
886:
878:
877:
871:
868:
867:
859:
858:
852:
846:
845:
842:
841:
833:
832:
826:
823:
822:
814:
813:
807:
801:
800:
795:
790:
786:
785:
775:
774:
771:
770:
759:
758:
756:
755:
750:
745:
740:
735:
730:
725:
720:
715:
709:
707:
703:
702:
700:
699:
694:
689:
684:
679:
673:
671:
667:
666:
664:
663:
658:
653:
648:
643:
638:
633:
627:
625:
621:
620:
610:
609:
606:
605:
602:
601:
593:
592:
567:
561:
560:
557:
556:
548:
547:
544:
543:
541:
540:
536:
532:
528:
524:
520:
516:
512:
508:
504:
500:
497:
496:
485:
482:
481:
479:
478:
474:
470:
466:
462:
458:
454:
450:
446:
442:
438:
435:
434:
422:
421:
413:
402:
396:
395:
392:RNA expression
384:
383:
380:
379:
371:
367:
366:
358:
355:
350:
344:
343:
334:
327:
321:
317:
316:
311:
305:
304:
296:
295:
283:
282:
279:
278:
270:
266:
265:
257:
254:
249:
243:
242:
233:
226:
220:
216:
215:
208:
202:
201:
193:
192:
180:
179:
172:
166:
165:
122:
118:
117:
109:
101:
100:
96:
95:
92:
91:
88:
87:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2696:
2685:
2682:
2681:
2679:
2667:
2663:
2659:
2655:
2650:
2645:
2641:
2637:
2636:J. Biol. Chem
2633:
2628:
2624:
2620:
2616:
2612:
2609:(4): 487–92.
2608:
2604:
2599:
2595:
2591:
2587:
2583:
2578:
2573:
2569:
2565:
2564:J. Biol. Chem
2561:
2556:
2552:
2548:
2543:
2538:
2534:
2530:
2526:
2522:
2518:
2513:
2509:
2505:
2501:
2497:
2492:
2487:
2483:
2479:
2476:(4): 932–40.
2475:
2471:
2467:
2462:
2458:
2454:
2450:
2446:
2442:
2438:
2434:
2430:
2425:
2421:
2417:
2413:
2409:
2404:
2399:
2395:
2391:
2390:J. Biol. Chem
2387:
2382:
2378:
2374:
2370:
2366:
2361:
2356:
2352:
2348:
2347:J. Biol. Chem
2344:
2339:
2335:
2331:
2327:
2323:
2318:
2313:
2309:
2305:
2304:J. Biol. Chem
2301:
2296:
2292:
2288:
2283:
2278:
2274:
2270:
2269:J. Biol. Chem
2266:
2261:
2257:
2253:
2248:
2243:
2239:
2235:
2231:
2226:
2222:
2218:
2213:
2208:
2204:
2200:
2196:
2192:
2188:
2183:
2179:
2175:
2171:
2167:
2164:(3): 424–36.
2163:
2159:
2153:
2149:
2145:
2141:
2137:
2132:
2127:
2124:(2): 567–70.
2123:
2119:
2118:J. Biol. Chem
2115:
2110:
2106:
2102:
2098:
2094:
2090:
2086:
2081:
2077:
2073:
2068:
2063:
2059:
2055:
2051:
2047:
2043:
2038:
2034:
2030:
2026:
2022:
2017:
2012:
2008:
2004:
2003:J. Biol. Chem
2000:
1995:
1991:
1987:
1983:
1979:
1975:
1971:
1967:
1963:
1958:
1957:
1952:
1943:
1939:
1934:
1929:
1924:
1919:
1915:
1911:
1907:
1903:
1899:
1892:
1889:
1884:
1880:
1876:
1872:
1867:
1862:
1858:
1854:
1853:J. Biol. Chem
1850:
1843:
1840:
1835:
1831:
1827:
1823:
1818:
1813:
1809:
1805:
1804:J. Biol. Chem
1801:
1794:
1791:
1786:
1782:
1778:
1774:
1771:(6): 644–51.
1770:
1766:
1759:
1756:
1751:
1747:
1743:
1739:
1735:
1731:
1727:
1723:
1716:
1713:
1708:
1704:
1700:
1696:
1691:
1686:
1682:
1678:
1677:J. Biol. Chem
1674:
1667:
1664:
1659:
1655:
1650:
1645:
1640:
1635:
1631:
1627:
1624:(4): 1633–8.
1623:
1619:
1615:
1608:
1605:
1600:
1596:
1592:
1588:
1585:(4): 487–92.
1584:
1580:
1573:
1570:
1565:
1561:
1557:
1553:
1548:
1543:
1540:(2): 567–70.
1539:
1535:
1534:J. Biol. Chem
1531:
1524:
1522:
1518:
1513:
1509:
1504:
1499:
1494:
1489:
1485:
1481:
1477:
1469:
1467:
1463:
1458:
1454:
1449:
1444:
1440:
1436:
1432:
1428:
1427:Plant Physiol
1424:
1417:
1415:
1411:
1406:
1400:
1398:
1394:
1389:
1385:
1381:
1377:
1373:
1369:
1362:
1359:
1354:
1350:
1345:
1340:
1336:
1332:
1328:
1324:
1320:
1313:
1310:
1305:
1301:
1295:
1292:
1287:
1283:
1277:
1274:
1270:
1266:
1261:
1259:
1257:
1253:
1249:
1245:
1240:
1238:
1236:
1232:
1225:
1220:
1217:
1214:
1211:
1208:
1205:
1204:
1203:
1201:
1193:
1191:
1189:
1185:
1181:
1176:
1174:
1170:
1166:
1165:recombination
1162:
1158:
1150:
1148:
1141:
1139:
1137:
1134:
1130:
1126:
1114:
1109:
1105:
1101:
1098:
1094:
1087:
1085:
1082:
1078:
1074:
1070:
1067:
1063:
1059:
1052:
1050:
1046:
1042:
1036:
1032:
1029:
1023:
1021:
1015:
1011:
1008:
1004:
997:
995:
991:
987:
981:
977:
974:
968:
966:
962:
958:
954:
948:
944:
941:
939:RefSeq (mRNA)
937:
930:
929:
924:
920:
917:
911:
910:
905:
901:
898:
896:
892:
885:
884:
879:
875:
872:
866:
865:
860:
856:
853:
851:
847:
840:
839:
834:
830:
827:
821:
820:
815:
811:
808:
806:
802:
799:
796:
794:
791:
787:
784:
780:
776:
769:
765:
760:
754:
751:
749:
746:
744:
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
711:
710:
708:
705:
704:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
674:
672:
669:
668:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
628:
626:
623:
622:
619:
618:Gene ontology
615:
611:
599:
594:
590:
583:
576:
571:
568:
566:
562:
554:
549:
538:
534:
530:
526:
522:
518:
514:
510:
506:
502:
501:
498:
494:
489:
486:
476:
472:
468:
464:
460:
457:renal medulla
456:
452:
448:
444:
440:
439:
436:
432:
427:
424:
423:
420:
418:
414:
412:
411:
407:
406:
403:
401:
397:
393:
389:
385:
377:
372:
368:
364:
359:
353:15|15 A1
349:
345:
338:
331:
325:
318:
310:
306:
302:
297:
293:
288:
284:
276:
271:
267:
263:
258:
248:
244:
237:
230:
224:
217:
213:
207:
203:
199:
194:
190:
185:
181:
177:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
127:
119:
114:
107:
102:
97:
86:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
2639:
2635:
2606:
2602:
2567:
2563:
2524:
2520:
2473:
2469:
2432:
2428:
2393:
2389:
2350:
2346:
2307:
2303:
2272:
2268:
2240:(1): 24–33.
2237:
2233:
2194:
2190:
2161:
2157:
2121:
2117:
2091:(2): 344–7.
2088:
2084:
2049:
2045:
2006:
2002:
1965:
1961:
1905:
1901:
1891:
1856:
1852:
1842:
1807:
1803:
1793:
1768:
1764:
1758:
1725:
1721:
1715:
1680:
1676:
1666:
1621:
1617:
1607:
1582:
1578:
1572:
1537:
1533:
1483:
1479:
1430:
1426:
1374:(2): 331–7.
1371:
1367:
1361:
1326:
1322:
1312:
1303:
1294:
1285:
1276:
1197:
1194:Interactions
1177:
1154:
1145:
1132:
1124:
1123:
1045:NP_001276377
1041:NP_001276376
1038:
1017:
990:NM_001289448
986:NM_001289447
983:
953:NM_001033673
950:
926:
907:
881:
862:
836:
817:
797:
792:
535:otic placode
531:otic vesicle
511:spermatocyte
415:
408:
121:External IDs
72:
1188:infertility
687:nucleoplasm
374:10,499,149
361:10,486,104
273:34,918,989
260:34,905,260
99:Identifiers
1486:: e68677.
1271:, May 2017
1250:, May 2017
1226:References
1184:germ cells
753:DNA repair
682:chromosome
419:(ortholog)
142:HomoloGene
2521:Genes Dev
2491:2297/1794
1323:Genes Dev
1049:NP_035362
1020:NP_002844
994:NM_011232
965:NM_133377
961:NM_133282
957:NM_002853
783:Orthologs
170:EC number
150:GeneCards
2678:Category
2666:35202138
2658:11994305
2623:11944979
2603:Genomics
2594:24820773
2586:11907025
2551:11799063
2508:20694221
2500:11573955
2449:11418864
2420:25624886
2412:11340080
2377:34505615
2369:10884395
2334:24638557
2326:10852904
2291:10846170
2256:10777662
2234:Genomics
2221:10359610
2158:Genomics
2148:28787137
2085:Genomics
2033:24604811
1990:45135386
1942:11572977
1883:35202138
1875:11994305
1834:24820773
1826:11907025
1785:14611806
1765:Genomics
1742:11418864
1707:34505615
1699:10884395
1658:12578958
1599:11944979
1579:Genomics
1564:28787137
1512:35133274
1457:27512017
1368:Genomics
1267:–
1246:–
1200:interact
1142:Function
1097:Wikidata
762:Sources:
527:ectoderm
507:epiblast
176:3.1.11.2
2457:4429058
2178:9878245
2140:9872989
2105:9828139
2076:9705507
2025:9660799
1982:8361362
1910:Bibcode
1750:4429058
1626:Bibcode
1556:9872989
1503:8824475
1448:5047095
1388:9828137
1353:9716408
1269:Ensembl
1248:Ensembl
1157:meiosis
1155:During
1151:Meiosis
1129:protein
895:UniProt
850:Ensembl
789:Species
768:QuickGO
697:nucleus
469:pylorus
449:urethra
394:pattern
138:1316678
106:Aliases
2664:
2656:
2621:
2592:
2584:
2549:
2542:155323
2539:
2506:
2498:
2455:
2447:
2429:Nature
2418:
2410:
2375:
2367:
2332:
2324:
2289:
2254:
2219:
2209:
2176:
2146:
2138:
2103:
2074:
2067:147814
2064:
2031:
2023:
1988:
1980:
1940:
1930:
1881:
1873:
1832:
1824:
1783:
1748:
1740:
1722:Nature
1705:
1697:
1656:
1649:149884
1646:
1597:
1562:
1554:
1510:
1500:
1455:
1445:
1386:
1351:
1344:317084
1341:
1215:, and
1202:with:
1083:search
1081:PubMed
928:Q9QWZ1
909:O60671
805:Entrez
565:BioGPS
519:morula
503:embryo
473:cardia
445:nipple
252:5p13.2
130:603153
2662:S2CID
2590:S2CID
2504:S2CID
2453:S2CID
2416:S2CID
2373:S2CID
2330:S2CID
2212:25401
2144:S2CID
2029:S2CID
1986:S2CID
1933:58713
1879:S2CID
1830:S2CID
1746:S2CID
1703:S2CID
1560:S2CID
1480:Elife
1219:RAD9A
1213:RAD17
1127:is a
838:19355
798:Mouse
793:Human
764:Amigo
417:Mouse
410:Human
357:Start
292:Mouse
256:Start
189:Human
146:37695
2654:PMID
2619:PMID
2582:PMID
2547:PMID
2496:PMID
2445:PMID
2408:PMID
2365:PMID
2322:PMID
2287:PMID
2252:PMID
2217:PMID
2174:PMID
2136:PMID
2101:PMID
2072:PMID
2021:PMID
1978:PMID
1938:PMID
1871:PMID
1822:PMID
1781:PMID
1738:PMID
1695:PMID
1654:PMID
1595:PMID
1552:PMID
1508:PMID
1453:PMID
1384:PMID
1349:PMID
1207:HUS1
1186:and
1175:.
1136:gene
1133:RAD1
819:5810
400:Bgee
348:Band
309:Chr.
247:Band
206:Chr.
154:RAD1
126:OMIM
113:RAD1
83:3GGR
79:3G65
75:3A1J
56:RCSB
53:PDBe
22:RAD1
2644:doi
2640:277
2611:doi
2572:doi
2568:277
2537:PMC
2529:doi
2486:hdl
2478:doi
2474:287
2437:doi
2433:411
2398:doi
2394:276
2355:doi
2351:275
2312:doi
2308:275
2277:doi
2273:275
2242:doi
2207:PMC
2199:doi
2166:doi
2126:doi
2122:274
2093:doi
2062:PMC
2054:doi
2011:doi
2007:273
1970:doi
1928:PMC
1918:doi
1861:doi
1857:277
1812:doi
1808:277
1773:doi
1730:doi
1726:411
1685:doi
1681:275
1644:PMC
1634:doi
1622:100
1587:doi
1542:doi
1538:274
1498:PMC
1488:doi
1443:PMC
1435:doi
1431:172
1376:doi
1339:PMC
1331:doi
1161:DNA
370:End
269:End
158:OMA
134:MGI
46:PDB
2680::
2660:.
2652:.
2638:.
2634:.
2617:.
2607:79
2605:.
2588:.
2580:.
2566:.
2562:.
2545:.
2535:.
2525:16
2523:.
2519:.
2502:.
2494:.
2484:.
2472:.
2468:.
2451:.
2443:.
2431:.
2414:.
2406:.
2392:.
2388:.
2371:.
2363:.
2349:.
2345:.
2328:.
2320:.
2306:.
2302:.
2285:.
2271:.
2267:.
2250:.
2238:65
2236:.
2232:.
2215:.
2205:.
2195:10
2193:.
2189:.
2172:.
2162:54
2160:.
2142:.
2134:.
2120:.
2116:.
2099:.
2089:54
2087:.
2070:.
2060:.
2050:26
2048:.
2044:.
2027:.
2019:.
2005:.
2001:.
1984:.
1976:.
1964:.
1936:.
1926:.
1916:.
1906:98
1904:.
1900:.
1877:.
1869:.
1855:.
1851:.
1828:.
1820:.
1806:.
1802:.
1779:.
1769:82
1767:.
1744:.
1736:.
1724:.
1701:.
1693:.
1679:.
1675:.
1652:.
1642:.
1632:.
1620:.
1616:.
1593:.
1583:79
1581:.
1558:.
1550:.
1536:.
1532:.
1520:^
1506:.
1496:.
1484:11
1482:.
1478:.
1465:^
1451:.
1441:.
1429:.
1425:.
1413:^
1396:^
1382:.
1372:54
1370:.
1347:.
1337:.
1327:12
1325:.
1321:.
1302:.
1284:.
1255:^
1234:^
1190:.
1138:.
766:/
376:bp
363:bp
275:bp
262:bp
156:;
152::
148:;
144::
140:;
136::
132:;
128::
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2668:.
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2258:.
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2168::
2150:.
2128::
2107:.
2095::
2078:.
2056::
2035:.
2013::
1992:.
1972::
1966:8
1944:.
1920::
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1288:.
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160::
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