Knowledge (XXG)

RBM39

Source 📝

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The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a
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Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region".
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Sun NN, Fastje CD, Wong SS, Sheppard PR, Macdonald SJ, Ridenour G, Hyde JD, Witten ML (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line".
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transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.
793: 157: 774: 1812: 1788: 1312: 1807: 1694: 1294: 52: 321: 1136: 1129: 298: 1382: 1281: 1260: 220: 195: 1277: 1256: 1559:"Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta" 137: 1220: 1449:"Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors" 1403:"Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors" 334: 233: 1781: 327: 226: 1687: 838: 145: 1332:"Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma" 1224: 819: 1228: 1512:
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics".
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Dowhan DH, Hong EP, Auboeuf D, Dennis AP, Wilson MM, Berget SM, O'Malley BW (2005).
149: 1664: 1631:"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" 1549: 407: 186: 1575: 1558: 173: 1317:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006).
1613: 1584: 1541: 1504: 1474: 1465: 1448: 1428: 1419: 1402: 1723:: solution structure of RNA binding domain in RNA binding motif protein 23 1365: 1176: 1171: 1160: 887: 868: 864: 1533: 1192: 850: 805: 1347: 128:, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2, RNA binding motif protein 39 94: 90: 86: 82: 78: 74: 1144: 760: 1742: 1232: 723: 719: 1750: 1199: 141: 1676: 588: 1672: 397: 1762: 1330:
Imai H, Chan EK, Kiyosawa K, Fu XD, Tan EM (Dec 1993).
562: 1069: 1024: 962: 905: 1273: 1271: 1269: 1252: 1250: 1248: 1383:"Entrez Gene: RBM39 RNA binding motif protein 39" 344: 243: 16:Protein-coding gene in the species Homo sapiens 1396: 1394: 1392: 1278:GRCm38: Ensembl release 89: ENSMUSG00000027620 1782: 1688: 8: 1257:GRCh38: Ensembl release 89: ENSG00000131051 1789: 1775: 1695: 1681: 1673: 1401:Jung DJ, Na SY, Na DS, Lee JW (Jan 2002). 1066: 1021: 959: 902: 734: 699:regulation of transcription, DNA-templated 604: 385: 284: 181: 63: 1646: 1574: 1464: 1418: 1355: 1377: 1375: 1710: 1244: 1447:Jung DJ, Na SY, Na DS, Lee JW (2002). 18: 349: 310: 305: 248: 207: 202: 7: 1739: 1737: 1761:. You can help Knowledge (XXG) by 878: 855: 829: 810: 784: 765: 567: 485: 423: 402: 14: 1195:that in humans is encoded by the 1741: 1713: 1594:Toxicology and Industrial Health 578: 571: 333: 326: 320: 297: 232: 225: 219: 194: 27: 1813:Human chromosome 20 gene stubs 589:More reference expression data 551:More reference expression data 1: 1497:10.1016/S0888-7543(03)00235-0 663:microtubule organizing center 318: 217: 1808:Genes on human chromosome 20 1576:10.1016/j.molcel.2004.12.025 704:transcription, DNA-templated 447:right lobe of thyroid gland 1829: 1736: 1648:10.1016/j.cell.2006.09.026 673:protein-containing complex 459:left lobe of thyroid gland 1708: 1606:10.1191/0748233703th185oa 1313:"Mouse PubMed Reference:" 1295:"Human PubMed Reference:" 1175: 1170: 1166: 1159: 1143: 1137:Chr 2: 156.15 – 156.18 Mb 1124: 1093: 1048: 1017: 986: 929: 898: 885: 881: 862: 858: 849: 836: 832: 817: 813: 804: 791: 787: 772: 768: 759: 744: 737: 733: 717: 607: 603: 586: 570: 561: 548: 533:medullary collecting duct 497: 488: 435: 426: 396: 388: 384: 367: 354: 317: 296: 287: 283: 266: 253: 216: 193: 184: 180: 135: 132: 122: 115: 110: 71: 66: 49: 44: 39: 35: 26: 21: 1219:RBM39 has been shown to 648:microtubule cytoskeleton 517:Rostral migratory stream 1225:Estrogen receptor alpha 1130:Chr 20: 35.7 – 35.74 Mb 1466:10.1074/jbc.M110417200 1420:10.1074/jbc.M110417200 1229:Estrogen receptor beta 1189:RNA-binding protein 39 509:neural layer of retina 210:Chromosome 20 (human) 622:nucleic acid binding 312:Chromosome 2 (mouse) 67:List of PDB id codes 40:Available structures 1534:10.1038/nature03207 1526:2005Natur.433...77A 475:canal of the cervix 1749:This article on a 839:ENSMUSG00000027620 682:Biological process 641:Cellular component 615:Molecular function 439:right uterine tube 1770: 1769: 1731: 1730: 1348:10.1172/JCI116848 1186: 1185: 1182: 1181: 1155: 1154: 1120: 1119: 1063: 1062: 1013: 1012: 956: 955: 894: 893: 875: 874: 845: 844: 826: 825: 800: 799: 781: 780: 729: 728: 599: 598: 595: 594: 557: 556: 544: 543: 482: 481: 380: 379: 279: 278: 174:RBM39 - orthologs 106: 105: 102: 101: 50:Ortholog search: 1820: 1791: 1784: 1777: 1745: 1738: 1717: 1697: 1690: 1683: 1674: 1668: 1650: 1625: 1600:(7–10): 157–63. 1588: 1578: 1553: 1508: 1478: 1468: 1433: 1432: 1422: 1398: 1387: 1386: 1379: 1370: 1369: 1359: 1327: 1321: 1320: 1309: 1303: 1302: 1291: 1285: 1275: 1264: 1254: 1168: 1167: 1139: 1132: 1115: 1067: 1058: 1022: 1018:RefSeq (protein) 1008: 960: 951: 903: 879: 856: 830: 811: 785: 766: 735: 605: 591: 582: 575: 568: 553: 513:ventricular zone 501:genital tubercle 493: 491:Top expressed in 486: 471:ventricular zone 431: 429:Top expressed in 424: 403: 386: 376: 363: 352: 337: 330: 324: 313: 301: 285: 275: 262: 251: 236: 229: 223: 212: 198: 182: 176: 127: 120: 97: 64: 58: 37: 36: 31: 19: 1828: 1827: 1823: 1822: 1821: 1819: 1818: 1817: 1798: 1797: 1796: 1795: 1734: 1732: 1727: 1724: 1718: 1704: 1701: 1671: 1628: 1591: 1556: 1520:(7021): 77–83. 1511: 1481: 1446: 1442: 1440:Further reading 1437: 1436: 1400: 1399: 1390: 1381: 1380: 1373: 1329: 1328: 1324: 1311: 1310: 1306: 1293: 1292: 1288: 1276: 1267: 1255: 1246: 1241: 1217: 1208: 1177:View/Edit Mouse 1172:View/Edit Human 1135: 1128: 1125:Location (UCSC) 1111: 1107: 1103: 1099: 1095: 1089: 1085: 1081: 1077: 1073: 1054: 1050: 1044: 1040: 1036: 1032: 1028: 1004: 1000: 996: 992: 988: 982: 978: 974: 970: 966: 947: 943: 939: 935: 931: 925: 921: 917: 913: 909: 867: 820:ENSG00000131051 713: 689:mRNA processing 677: 636: 627:protein binding 587: 577: 576: 549: 540: 535: 531: 527: 523: 519: 515: 511: 507: 503: 489: 478: 473: 469: 465: 461: 457: 453: 449: 445: 443:Achilles tendon 441: 427: 371: 358: 350: 340: 339: 338: 331: 311: 288:Gene location ( 270: 257: 249: 239: 238: 237: 230: 208: 185:Gene location ( 136: 123: 116: 73: 51: 17: 12: 11: 5: 1826: 1824: 1816: 1815: 1810: 1800: 1799: 1794: 1793: 1786: 1779: 1771: 1768: 1767: 1746: 1729: 1728: 1726: 1725: 1719: 1712: 1709: 1706: 1705: 1702: 1700: 1699: 1692: 1685: 1677: 1670: 1669: 1626: 1589: 1554: 1509: 1479: 1459:(2): 1229–34. 1443: 1441: 1438: 1435: 1434: 1413:(2): 1229–34. 1388: 1371: 1342:(5): 2419–26. 1322: 1304: 1286: 1265: 1243: 1242: 1240: 1237: 1216: 1213: 1207: 1204: 1184: 1183: 1180: 1179: 1174: 1164: 1163: 1157: 1156: 1153: 1152: 1150: 1148: 1141: 1140: 1133: 1126: 1122: 1121: 1118: 1117: 1091: 1090: 1064: 1061: 1060: 1046: 1045: 1019: 1015: 1014: 1011: 1010: 984: 983: 957: 954: 953: 927: 926: 900: 896: 895: 892: 891: 883: 882: 876: 873: 872: 860: 859: 853: 847: 846: 843: 842: 834: 833: 827: 824: 823: 815: 814: 808: 802: 801: 798: 797: 789: 788: 782: 779: 778: 770: 769: 763: 757: 756: 751: 746: 742: 741: 731: 730: 727: 726: 715: 714: 712: 711: 706: 701: 696: 694:RNA processing 691: 685: 683: 679: 678: 676: 675: 670: 665: 660: 655: 650: 644: 642: 638: 637: 635: 634: 629: 624: 618: 616: 612: 611: 601: 600: 597: 596: 593: 592: 584: 583: 565: 559: 558: 555: 554: 546: 545: 542: 541: 539: 538: 534: 530: 526: 522: 518: 514: 510: 506: 505:tail of embryo 502: 498: 495: 494: 483: 480: 479: 477: 476: 472: 468: 467:body of uterus 464: 460: 456: 452: 448: 444: 440: 436: 433: 432: 420: 419: 411: 400: 394: 393: 390:RNA expression 382: 381: 378: 377: 369: 365: 364: 356: 353: 348: 342: 341: 332: 325: 319: 315: 314: 309: 303: 302: 294: 293: 281: 280: 277: 276: 268: 264: 263: 255: 252: 247: 241: 240: 231: 224: 218: 214: 213: 206: 200: 199: 191: 190: 178: 177: 134: 130: 129: 121: 113: 112: 108: 107: 104: 103: 100: 99: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1825: 1814: 1811: 1809: 1806: 1805: 1803: 1792: 1787: 1785: 1780: 1778: 1773: 1772: 1766: 1764: 1760: 1756: 1755:chromosome 20 1752: 1747: 1744: 1740: 1735: 1722: 1716: 1711: 1707: 1698: 1693: 1691: 1686: 1684: 1679: 1678: 1675: 1666: 1662: 1658: 1654: 1649: 1644: 1641:(3): 635–48. 1640: 1636: 1632: 1627: 1623: 1619: 1615: 1611: 1607: 1603: 1599: 1595: 1590: 1586: 1582: 1577: 1572: 1569:(3): 429–39. 1568: 1564: 1560: 1555: 1551: 1547: 1543: 1539: 1535: 1531: 1527: 1523: 1519: 1515: 1510: 1506: 1502: 1498: 1494: 1491:(1): 153–67. 1490: 1486: 1480: 1476: 1472: 1467: 1462: 1458: 1454: 1453:J. Biol. Chem 1450: 1445: 1444: 1439: 1430: 1426: 1421: 1416: 1412: 1408: 1407:J. Biol. Chem 1404: 1397: 1395: 1393: 1389: 1384: 1378: 1376: 1372: 1367: 1363: 1358: 1353: 1349: 1345: 1341: 1337: 1336:J Clin Invest 1333: 1326: 1323: 1318: 1314: 1308: 1305: 1300: 1296: 1290: 1287: 1283: 1279: 1274: 1272: 1270: 1266: 1262: 1258: 1253: 1251: 1249: 1245: 1238: 1236: 1234: 1230: 1226: 1222: 1214: 1212: 1205: 1203: 1201: 1198: 1194: 1190: 1178: 1173: 1169: 1165: 1162: 1158: 1151: 1149: 1146: 1142: 1138: 1134: 1131: 1127: 1123: 1116: 1114: 1110: 1106: 1102: 1098: 1092: 1088: 1084: 1080: 1076: 1072: 1068: 1065: 1059: 1057: 1053: 1047: 1043: 1039: 1035: 1031: 1027: 1023: 1020: 1016: 1009: 1007: 1003: 999: 995: 991: 985: 981: 977: 973: 969: 965: 961: 958: 952: 950: 946: 942: 938: 934: 928: 924: 920: 916: 912: 908: 904: 901: 899:RefSeq (mRNA) 897: 890: 889: 884: 880: 877: 871: 870: 866: 861: 857: 854: 852: 848: 841: 840: 835: 831: 828: 822: 821: 816: 812: 809: 807: 803: 796: 795: 790: 786: 783: 777: 776: 771: 767: 764: 762: 758: 755: 752: 750: 747: 743: 740: 736: 732: 725: 721: 716: 710: 707: 705: 702: 700: 697: 695: 692: 690: 687: 686: 684: 681: 680: 674: 671: 669: 668:nuclear speck 666: 664: 661: 659: 656: 654: 651: 649: 646: 645: 643: 640: 639: 633: 630: 628: 625: 623: 620: 619: 617: 614: 613: 610: 609:Gene ontology 606: 602: 590: 585: 581: 574: 569: 566: 564: 560: 552: 547: 537:Gonadal ridge 536: 532: 528: 524: 520: 516: 512: 508: 504: 500: 499: 496: 492: 487: 484: 474: 470: 466: 462: 458: 454: 450: 446: 442: 438: 437: 434: 430: 425: 422: 421: 418: 416: 412: 410: 409: 405: 404: 401: 399: 395: 391: 387: 383: 375: 370: 366: 362: 357: 347: 343: 336: 329: 323: 316: 308: 304: 300: 295: 291: 286: 282: 274: 269: 265: 261: 256: 246: 242: 235: 228: 222: 215: 211: 205: 201: 197: 192: 188: 183: 179: 175: 171: 167: 163: 159: 155: 151: 147: 143: 139: 131: 126: 119: 114: 109: 98: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 1763:expanding it 1748: 1733: 1720: 1638: 1634: 1597: 1593: 1566: 1562: 1517: 1513: 1488: 1484: 1456: 1452: 1410: 1406: 1339: 1335: 1325: 1316: 1307: 1298: 1289: 1218: 1215:Interactions 1209: 1196: 1188: 1187: 1113:NP_001349698 1109:NP_001349697 1105:NP_001349696 1101:NP_001349695 1097:NP_001349694 1094: 1087:NP_001349693 1083:NP_001349692 1075:NP_001278044 1071:NP_001278043 1049: 1042:NP_001310353 1038:NP_001310352 1034:NP_001310351 1030:NP_001229529 1026:NP_001229528 1006:NM_001362769 1002:NM_001362768 998:NM_001362767 994:NM_001362766 990:NM_001362765 987: 980:NM_001362764 976:NM_001362763 968:NM_001291115 964:NM_001291114 949:NM_001323424 945:NM_001323423 941:NM_001323422 930: 911:NM_001242600 907:NM_001242599 886: 863: 837: 818: 792: 773: 753: 748: 709:RNA splicing 521:spermatocyte 413: 406: 372:156,180,238 359:156,147,239 133:External IDs 72: 1703:PDB gallery 658:nucleoplasm 632:RNA binding 529:granulocyte 525:neural tube 463:sural nerve 455:right ovary 351:2|2 H1 271:35,742,312 258:35,701,347 111:Identifiers 1802:Categories 1284:, May 2017 1263:, May 2017 1239:References 451:left ovary 417:(ortholog) 154:HomoloGene 1753:on human 1563:Mol. Cell 1079:NP_573505 1056:NP_909122 1052:NP_004893 972:NM_133242 937:NM_184244 933:NM_184241 923:NM_184237 919:NM_184234 915:NM_004902 739:Orthologs 162:GeneCards 1657:17081983 1622:14394243 1614:15747776 1585:15694343 1542:15635413 1505:14667819 1485:Genomics 1475:11704680 1429:11704680 1280:– 1259:– 1221:interact 1206:Function 1161:Wikidata 718:Sources: 250:20q11.22 1665:7827573 1550:4344740 1522:Bibcode 1366:8227358 1282:Ensembl 1261:Ensembl 1193:protein 851:UniProt 806:Ensembl 745:Species 724:QuickGO 653:nucleus 392:pattern 150:2157953 118:Aliases 1663:  1655:  1620:  1612:  1583:  1548:  1540:  1514:Nature 1503:  1473:  1427:  1364:  1357:288425 1354:  1147:search 1145:PubMed 888:Q8VH51 869:Q5QP23 865:Q14498 794:170791 761:Entrez 563:BioGPS 158:136465 142:604739 1757:is a 1661:S2CID 1618:S2CID 1546:S2CID 1233:C-jun 1223:with 1197:RBM39 1191:is a 754:Mouse 749:Human 720:Amigo 415:Mouse 408:Human 355:Start 290:Mouse 254:Start 187:Human 166:RBM39 125:RBM39 22:RBM39 1759:stub 1751:gene 1721:2cq4 1653:PMID 1635:Cell 1610:PMID 1581:PMID 1538:PMID 1501:PMID 1471:PMID 1425:PMID 1362:PMID 1231:and 1200:gene 775:9584 398:Bgee 346:Band 307:Chr. 245:Band 204:Chr. 138:OMIM 95:4YUD 91:4OZ1 87:4OZ0 83:4OO6 79:2MHN 75:2JRS 56:RCSB 53:PDBe 1643:doi 1639:127 1602:doi 1571:doi 1530:doi 1518:433 1493:doi 1461:doi 1457:277 1415:doi 1411:277 1352:PMC 1344:doi 368:End 267:End 170:OMA 146:MGI 46:PDB 1804:: 1659:. 1651:. 1637:. 1633:. 1616:. 1608:. 1598:19 1596:. 1579:. 1567:17 1565:. 1561:. 1544:. 1536:. 1528:. 1516:. 1499:. 1489:83 1487:. 1469:. 1455:. 1451:. 1423:. 1409:. 1405:. 1391:^ 1374:^ 1360:. 1350:. 1340:92 1338:. 1334:. 1315:. 1297:. 1268:^ 1247:^ 1235:. 1227:, 1202:. 722:/ 374:bp 361:bp 273:bp 260:bp 168:; 164:: 160:; 156:: 152:; 148:: 144:; 140:: 93:, 89:, 85:, 81:, 77:, 1790:e 1783:t 1776:v 1765:. 1696:e 1689:t 1682:v 1667:. 1645:: 1624:. 1604:: 1587:. 1573:: 1552:. 1532:: 1524:: 1507:. 1495:: 1477:. 1463:: 1431:. 1417:: 1385:. 1368:. 1346:: 1319:. 1301:. 292:) 189:) 172::

Index


PDB
PDBe
RCSB
2JRS
2MHN
4OO6
4OZ0
4OZ1
4YUD
Aliases
RBM39
OMIM
604739
MGI
2157953
HomoloGene
136465
GeneCards
RBM39
OMA
RBM39 - orthologs
Human
Chromosome 20 (human)
Chr.
Chromosome 20 (human)
Chromosome 20 (human)
Genomic location for RBM39
Genomic location for RBM39
Band

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