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RGS9

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are also involved), and is thought to be important in the development of tolerance to opioid drugs. RGS9-deficient mice exhibit some motor and cognitive difficulties however, so inhibition of this protein is likely to cause similar side effects.
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Granneman JG, Zhai Y, Zhu Z, et al. (1998). "Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene".
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Sánchez-Blázquez P, Rodríguez-Muñoz M, Montero C, Garzón J (January 2005). "RGS-Rz and RGS9-2 proteins control mu-opioid receptor desensitisation in CNS: the role of activated Galphaz subunits".
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There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in
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Nishiguchi KM, Sandberg MA, Kooijman AC, et al. (2004). "Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation".
1524:"Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization" 2320:: CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT 848: 829: 137: 2424: 1367:
Garzón J, Rodríguez-Díaz M, López-Fando A, Sánchez-Blázquez P (February 2001). "RGS9 proteins facilitate acute tolerance to mu-opioid effects".
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Zachariou V, Georgescu D, Sanchez N, Rahman Z, DiLeone R, Berton O, Neve RL, Sim-Selley LJ, Selley DE, Gold SJ, Nestler EJ (November 2003).
1255: 301: 52: 1079: 1614: 1072: 278: 1147: 1294: 1242: 1221: 200: 175: 1749:"Type 5 G Protein Subunit (G 5) Controls the Interaction of Regulator of G Protein Signaling 9 (RGS9) with Membrane Anchors" 1238: 1217: 117: 1913:
Zhang K, Howes KA, He W, et al. (2000). "Structure, alternative splicing, and expression of the human RGS9 gene".
314: 213: 2393: 2269: 307: 206: 2335:: CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT 893: 125: 1172:
RGS9-2 is of particular interest as the most important RGS protein involved in terminating signalling by the
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Yu H, Bondarenko VA, Yamazaki A (2001). "Inhibition of retinal guanylyl cyclase by the RGS9-1 N-terminus".
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Psifogeorgou K, Papakosta P, Russo SJ, Neve RL, Kardassis D, Gold SJ, Zachariou V (October 2007).
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Hooks SB, Martemyanov K, Zachariou V (January 2008). "A role of RGS proteins in drug addiction".
1594: 1504: 1402: 1173: 1158: 149: 2026:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1055: 1030: 996: 971: 2079:"The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo" 552: 2231: 2211: 2182: 2145: 2108: 2065: 2012: 1959: 1930: 1901: 1879: 1840:"High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods" 1826: 1780: 1729: 1680: 1631: 1586: 1545: 1496: 1461: 1394: 1349: 97: 45: 1747:
Masuho, I.; Wakasugi-Masuho, H.; Posokhova, E. N.; Patton, J. R.; Martemyanov, K. A. (2011).
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Ajit SK, Young KH (2004). "Enhancement of pheromone response by RGS9 and Gbeta5 in yeast".
369: 145: 1165:, while RGS9-2 is found in the brain, and regulates dopamine and opioid signaling in the 2133: 2041: 1988: 1855: 1437: 1325: 2370: 2103: 2094: 2078: 1775: 1748: 1724: 1699: 1675: 1650: 1344: 1309: 1196:
and DEP helical-extension domain in protein stability and membrane anchor association.
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RGS9 is differentially regulated by Guanine nucleotide-binding protein subunit beta-5 (
2060: 2025: 2007: 1972: 1926: 1456: 1421: 763: 758: 753: 748: 743: 738: 733: 728: 723: 718: 713: 708: 703: 698: 693: 677: 672: 667: 662: 657: 652: 647: 642: 637: 632: 611: 606: 601: 108:, PERRS, RGS9L, regulator of G-protein signaling 9, regulator of G protein signaling 9 28: 2413: 2366: 2240: 1874: 1839: 1581: 1564: 1492: 1380: 1166: 588: 1598: 1508: 1406: 129: 1973:"R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1" 1715: 387: 166: 2157: 153: 2207: 1278:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Martemyanov KA, Krispel CM, Lishko PV, Burns ME, Arshavsky VY (December 2008).
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Cheng JY, Luu CD, Yong VH, et al. (2007). "Bradyopsia in an Asian man".
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Garzón J, Rodríguez-Muñoz M, López-Fando A, Sánchez-Blázquez P (March 2005).
1805:"Normalization and subtraction: two approaches to facilitate gene discovery" 1765: 1446: 1334: 1151: 793: 616: 530: 408: 353: 340: 252: 239: 141: 2215: 2186: 2149: 2112: 2069: 2050: 2016: 1997: 1963: 1955: 1934: 1864: 1784: 1733: 1684: 1635: 1590: 1549: 1540: 1523: 1500: 1465: 1398: 1353: 1905: 1883: 1830: 1119: 1114: 1651:"RGS9-2: probing an intracellular modulator of behavior as a drug target" 1103: 938: 919: 2141: 1389: 2245: 2235: 1821: 1804: 905: 860: 74: 1162: 1150:, such as RGS9, are signaling proteins that suppress the activity of 1087: 815: 2354: 1698:
Blundell J, Hoang CV, Potts B, Gold SJ, Powell CM (January 2008).
1181: 778: 774: 2362: 1310:"Functional comparison of RGS9 splice isoforms in a living cell" 1189: 1177: 1139: 121: 2258: 1565:"RGS9-2 is a negative modulator of mu-opioid receptor function" 568: 2254: 1649:
Traynor JR, Terzi D, Caldarone BJ, Zachariou V (March 2009).
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Overview of all the structural information available in the
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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regulation of G protein-coupled receptor signaling pathway
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Martemyanov KA, Lishko PV, Calero N, et al. (2003).
377: 2374: 1295:"Entrez Gene: RGS9 regulator of G-protein signalling 9" 764:
regulation of calcium ion export across plasma membrane
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positive regulation of NMDA glutamate receptor activity
1142:, which codes for a protein involved in regulation of 542: 1044: 1015: 985: 956: 2244:(Mouse Regulator of G-protein signaling 9) at the 1838:Cowan CW, Fariss RN, Sokal I, et al. (1998). 1700:"Motor coordination deficits in mice lacking RGS9" 1234: 1232: 1230: 1213: 1211: 1209: 324: 223: 16:Protein-coding gene in the species Homo sapiens 1239:GRCm38: Ensembl release 89: ENSMUSG00000020599 2394: 2270: 8: 709:G protein-coupled receptor signaling pathway 1218:GRCh38: Ensembl release 89: ENSG00000108370 2401: 2387: 2277: 2263: 2255: 1422:"Essential role for RGS9 in opiate action" 789: 719:negative regulation of signal transduction 584: 365: 264: 161: 63: 2102: 2059: 2049: 2006: 1996: 1873: 1863: 1820: 1774: 1764: 1723: 1674: 1580: 1539: 1455: 1445: 1388: 1343: 1333: 1803:Bonaldo MF, Lennon G, Soares MB (1997). 1289: 1287: 2292: 1205: 517:paraventricular nucleus of hypothalamus 724:positive regulation of GTPase activity 18: 329: 290: 285: 228: 187: 182: 7: 2351: 2349: 1369:The European Journal of Neuroscience 1528:The Journal of Biological Chemistry 1132:Regulator of G-protein signalling 9 739:dopamine receptor signaling pathway 2095:10.1523/JNEUROSCI.23-32-10175.2003 1655:Trends in Pharmacological Sciences 1041: 1012: 982: 953: 929: 910: 884: 865: 839: 820: 678:intracellular anatomical structure 607:protein-containing complex binding 547: 465: 403: 382: 14: 1154:by promoting their deactivation. 714:intracellular signal transduction 2353: 2325: 2310: 2295: 1582:10.1111/j.1471-4159.2007.04812.x 1493:10.1016/j.neuropharm.2004.08.016 1381:10.1046/j.0953-816x.2000.01444.x 558: 551: 513:dorsomedial hypothalamic nucleus 313: 306: 300: 277: 212: 205: 199: 174: 27: 1753:Journal of Biological Chemistry 2425:Human chromosome 17 gene stubs 1716:10.1016/j.brainres.2007.11.017 569:More reference expression data 531:More reference expression data 1: 2167:Biochem. Biophys. Res. Commun 1944:Biochem. Biophys. Res. Commun 1927:10.1016/S0378-1119(99)00393-5 1146:inside cells. Members of the 668:postsynaptic density membrane 447:muscle layer of sigmoid colon 298: 197: 2420:Genes on human chromosome 17 2373:. You can help Knowledge by 2030:Proc. Natl. Acad. Sci. U.S.A 1977:Proc. Natl. Acad. Sci. U.S.A 1844:Proc. Natl. Acad. Sci. U.S.A 2208:10.1001/archopht.125.8.1138 663:photoreceptor disc membrane 653:photoreceptor outer segment 638:photoreceptor inner segment 2441: 2348: 2179:10.1016/j.bbrc.2004.09.100 1667:10.1016/j.tips.2008.11.006 1080:Chr 11: 109.12 – 109.19 Mb 694:nervous system development 617:signal transducer activity 2290: 1628:10.1016/j.bcp.2007.07.045 1569:Journal of Neurochemistry 1274:"Mouse PubMed Reference:" 1256:"Human PubMed Reference:" 1118: 1113: 1109: 1102: 1086: 1067: 1048: 1019: 1008: 989: 960: 949: 936: 932: 917: 913: 904: 891: 887: 872: 868: 859: 846: 842: 827: 823: 814: 799: 792: 788: 772: 602:GTPase activator activity 587: 583: 566: 550: 541: 528: 477: 468: 415: 406: 376: 368: 364: 347: 334: 297: 276: 267: 263: 246: 233: 196: 173: 164: 160: 115: 112: 102: 95: 90: 71: 66: 49: 44: 39: 35: 26: 21: 1971:Hu G, Wensel TG (2002). 1615:Biochemical Pharmacology 1766:10.1074/jbc.M111.241513 1447:10.1073/pnas.2232594100 1335:10.1073/pnas.0808941106 1073:Chr 17: 65.1 – 65.23 Mb 749:response to amphetamine 2051:10.1073/pnas.242603899 1998:10.1073/pnas.152094799 1956:10.1006/bbrc.2001.5346 1865:10.1073/pnas.95.9.5351 1541:10.1074/jbc.M407005200 493:superior frontal gyrus 481:neural layer of retina 331:11 E1|11 71.86 cM 754:response to estradiol 673:glutamatergic synapse 292:Chromosome 11 (mouse) 190:Chromosome 17 (human) 729:response to estrogen 704:response to stimulus 509:ventromedial nucleus 67:List of PDB id codes 40:Available structures 2142:10.1038/nature02170 2134:2004Natur.427...75N 2042:2002PNAS...9916899M 1989:2002PNAS...99.9755H 1856:1998PNAS...95.5351C 1759:(24): 21806–21813. 1438:2003PNAS..10013656Z 1326:2008PNAS..10520988M 1144:signal transduction 427:islet of Langerhans 2361:This article on a 1822:10.1101/gr.6.9.791 1174:mu opioid receptor 1159:rod and cone cells 894:ENSMUSG00000020599 687:Biological process 626:Cellular component 595:Molecular function 485:olfactory tubercle 451:anterior pituitary 2382: 2381: 2343: 2342: 2305:: RGS9 RGS DOMAIN 2036:(26): 16899–903. 1481:Neuropharmacology 1129: 1128: 1125: 1124: 1098: 1097: 1063: 1062: 1038: 1037: 1004: 1003: 979: 978: 945: 944: 926: 925: 900: 899: 881: 880: 855: 854: 836: 835: 784: 783: 699:visual perception 579: 578: 575: 574: 537: 536: 524: 523: 489:nucleus accumbens 462: 461: 435:left uterine tube 431:nucleus accumbens 360: 359: 259: 258: 86: 85: 82: 81: 50:Ortholog search: 2432: 2403: 2396: 2389: 2357: 2350: 2329: 2314: 2299: 2279: 2272: 2265: 2256: 2219: 2196:Arch. Ophthalmol 2190: 2161: 2116: 2106: 2089:(32): 10175–81. 2073: 2063: 2053: 2020: 2010: 2000: 1967: 1938: 1909: 1887: 1877: 1867: 1834: 1824: 1789: 1788: 1778: 1768: 1744: 1738: 1737: 1727: 1695: 1689: 1688: 1678: 1646: 1640: 1639: 1609: 1603: 1602: 1584: 1560: 1554: 1553: 1543: 1519: 1513: 1512: 1476: 1470: 1469: 1459: 1449: 1432:(23): 13656–61. 1417: 1411: 1410: 1392: 1364: 1358: 1357: 1347: 1337: 1320:(52): 20988–93. 1305: 1299: 1298: 1291: 1282: 1281: 1270: 1264: 1263: 1252: 1246: 1236: 1225: 1215: 1134:, also known as 1111: 1110: 1082: 1075: 1058: 1042: 1033: 1013: 1009:RefSeq (protein) 999: 983: 974: 954: 930: 911: 885: 866: 840: 821: 790: 585: 571: 562: 555: 548: 533: 473: 471:Top expressed in 466: 411: 409:Top expressed in 404: 383: 366: 356: 343: 332: 317: 310: 304: 293: 281: 265: 255: 242: 231: 216: 209: 203: 192: 178: 162: 156: 154:RGS9 - orthologs 107: 100: 77: 64: 58: 37: 36: 31: 19: 2440: 2439: 2435: 2434: 2433: 2431: 2430: 2429: 2410: 2409: 2408: 2407: 2346: 2344: 2339: 2336: 2330: 2321: 2315: 2306: 2300: 2286: 2283: 2252: 2227: 2222: 2193: 2164: 2119: 2076: 2023: 1983:(15): 9755–60. 1970: 1941: 1912: 1890: 1837: 1802: 1798: 1796:Further reading 1793: 1792: 1746: 1745: 1741: 1697: 1696: 1692: 1648: 1647: 1643: 1611: 1610: 1606: 1562: 1561: 1557: 1534:(10): 8951–60. 1521: 1520: 1516: 1478: 1477: 1473: 1419: 1418: 1414: 1366: 1365: 1361: 1307: 1306: 1302: 1293: 1292: 1285: 1272: 1271: 1267: 1254: 1253: 1249: 1237: 1228: 1216: 1207: 1202: 1120:View/Edit Mouse 1115:View/Edit Human 1078: 1071: 1068:Location (UCSC) 1054: 1050: 1029: 1025: 1021: 995: 991: 970: 966: 962: 875:ENSG00000108370 768: 744:protein folding 682: 658:plasma membrane 621: 612:GTPase activity 567: 557: 556: 529: 520: 515: 511: 507: 505:median eminence 503: 501:arcuate nucleus 499: 497:globus pallidus 495: 491: 487: 483: 469: 458: 453: 449: 445: 441: 437: 433: 429: 425: 423:caudate nucleus 421: 407: 351: 338: 330: 320: 319: 318: 311: 291: 268:Gene location ( 250: 237: 229: 219: 218: 217: 210: 188: 165:Gene location ( 116: 103: 96: 73: 51: 17: 12: 11: 5: 2438: 2436: 2428: 2427: 2422: 2412: 2411: 2406: 2405: 2398: 2391: 2383: 2380: 2379: 2358: 2341: 2340: 2338: 2337: 2331: 2324: 2322: 2316: 2309: 2307: 2301: 2294: 2291: 2288: 2287: 2284: 2282: 2281: 2274: 2267: 2259: 2250: 2249: 2226: 2225:External links 2223: 2221: 2220: 2202:(8): 1138–40. 2191: 2162: 2128:(6969): 75–8. 2117: 2074: 2021: 1968: 1939: 1910: 1894:Mol. Pharmacol 1888: 1835: 1815:(9): 791–806. 1799: 1797: 1794: 1791: 1790: 1739: 1704:Brain Research 1690: 1641: 1604: 1555: 1514: 1471: 1412: 1359: 1300: 1283: 1265: 1247: 1226: 1204: 1203: 1201: 1198: 1127: 1126: 1123: 1122: 1117: 1107: 1106: 1100: 1099: 1096: 1095: 1093: 1091: 1084: 1083: 1076: 1069: 1065: 1064: 1061: 1060: 1046: 1045: 1039: 1036: 1035: 1017: 1016: 1010: 1006: 1005: 1002: 1001: 987: 986: 980: 977: 976: 958: 957: 951: 947: 946: 943: 942: 934: 933: 927: 924: 923: 915: 914: 908: 902: 901: 898: 897: 889: 888: 882: 879: 878: 870: 869: 863: 857: 856: 853: 852: 844: 843: 837: 834: 833: 825: 824: 818: 812: 811: 806: 801: 797: 796: 786: 785: 782: 781: 770: 769: 767: 766: 761: 756: 751: 746: 741: 736: 731: 726: 721: 716: 711: 706: 701: 696: 690: 688: 684: 683: 681: 680: 675: 670: 665: 660: 655: 650: 645: 640: 635: 629: 627: 623: 622: 620: 619: 614: 609: 604: 598: 596: 592: 591: 581: 580: 577: 576: 573: 572: 564: 563: 545: 539: 538: 535: 534: 526: 525: 522: 521: 519: 518: 514: 510: 506: 502: 498: 494: 490: 486: 482: 478: 475: 474: 463: 460: 459: 457: 456: 452: 448: 444: 443:gastric mucosa 440: 436: 432: 428: 424: 420: 416: 413: 412: 400: 399: 391: 380: 374: 373: 370:RNA expression 362: 361: 358: 357: 349: 345: 344: 336: 333: 328: 322: 321: 312: 305: 299: 295: 294: 289: 283: 282: 274: 273: 261: 260: 257: 256: 248: 244: 243: 235: 232: 227: 221: 220: 211: 204: 198: 194: 193: 186: 180: 179: 171: 170: 158: 157: 114: 110: 109: 101: 93: 92: 88: 87: 84: 83: 80: 79: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2437: 2426: 2423: 2421: 2418: 2417: 2415: 2404: 2399: 2397: 2392: 2390: 2385: 2384: 2378: 2376: 2372: 2368: 2367:chromosome 17 2364: 2359: 2356: 2352: 2347: 2334: 2328: 2323: 2319: 2313: 2308: 2304: 2298: 2293: 2289: 2280: 2275: 2273: 2268: 2266: 2261: 2260: 2257: 2253: 2247: 2243: 2242: 2237: 2233: 2229: 2228: 2224: 2217: 2213: 2209: 2205: 2201: 2197: 2192: 2188: 2184: 2180: 2176: 2173:(2): 686–91. 2172: 2168: 2163: 2159: 2155: 2151: 2147: 2143: 2139: 2135: 2131: 2127: 2123: 2118: 2114: 2110: 2105: 2100: 2096: 2092: 2088: 2084: 2080: 2075: 2071: 2067: 2062: 2057: 2052: 2047: 2043: 2039: 2035: 2031: 2027: 2022: 2018: 2014: 2009: 2004: 1999: 1994: 1990: 1986: 1982: 1978: 1974: 1969: 1965: 1961: 1957: 1953: 1949: 1945: 1940: 1936: 1932: 1928: 1924: 1920: 1916: 1911: 1907: 1903: 1900:(4): 687–94. 1899: 1895: 1889: 1885: 1881: 1876: 1871: 1866: 1861: 1857: 1853: 1850:(9): 5351–6. 1849: 1845: 1841: 1836: 1832: 1828: 1823: 1818: 1814: 1810: 1806: 1801: 1800: 1795: 1786: 1782: 1777: 1772: 1767: 1762: 1758: 1754: 1750: 1743: 1740: 1735: 1731: 1726: 1721: 1717: 1713: 1709: 1705: 1701: 1694: 1691: 1686: 1682: 1677: 1672: 1668: 1664: 1661:(3): 105–11. 1660: 1656: 1652: 1645: 1642: 1637: 1633: 1629: 1625: 1621: 1617: 1616: 1608: 1605: 1600: 1596: 1592: 1588: 1583: 1578: 1575:(2): 617–25. 1574: 1570: 1566: 1559: 1556: 1551: 1547: 1542: 1537: 1533: 1529: 1525: 1518: 1515: 1510: 1506: 1502: 1498: 1494: 1490: 1487:(1): 134–50. 1486: 1482: 1475: 1472: 1467: 1463: 1458: 1453: 1448: 1443: 1439: 1435: 1431: 1427: 1423: 1416: 1413: 1408: 1404: 1400: 1396: 1391: 1386: 1382: 1378: 1375:(4): 801–11. 1374: 1370: 1363: 1360: 1355: 1351: 1346: 1341: 1336: 1331: 1327: 1323: 1319: 1315: 1311: 1304: 1301: 1296: 1290: 1288: 1284: 1279: 1275: 1269: 1266: 1261: 1257: 1251: 1248: 1244: 1240: 1235: 1233: 1231: 1227: 1223: 1219: 1214: 1212: 1210: 1206: 1199: 1197: 1195: 1191: 1186: 1183: 1179: 1175: 1170: 1168: 1167:basal ganglia 1164: 1160: 1155: 1153: 1149: 1145: 1141: 1138:, is a human 1137: 1133: 1121: 1116: 1112: 1108: 1105: 1101: 1094: 1092: 1089: 1085: 1081: 1077: 1074: 1070: 1066: 1059: 1057: 1053: 1047: 1043: 1040: 1034: 1032: 1028: 1024: 1018: 1014: 1011: 1007: 1000: 998: 994: 988: 984: 981: 975: 973: 969: 965: 959: 955: 952: 950:RefSeq (mRNA) 948: 941: 940: 935: 931: 928: 922: 921: 916: 912: 909: 907: 903: 896: 895: 890: 886: 883: 877: 876: 871: 867: 864: 862: 858: 851: 850: 845: 841: 838: 832: 831: 826: 822: 819: 817: 813: 810: 807: 805: 802: 798: 795: 791: 787: 780: 776: 771: 765: 762: 760: 757: 755: 752: 750: 747: 745: 742: 740: 737: 735: 732: 730: 727: 725: 722: 720: 717: 715: 712: 710: 707: 705: 702: 700: 697: 695: 692: 691: 689: 686: 685: 679: 676: 674: 671: 669: 666: 664: 661: 659: 656: 654: 651: 649: 646: 644: 641: 639: 636: 634: 631: 630: 628: 625: 624: 618: 615: 613: 610: 608: 605: 603: 600: 599: 597: 594: 593: 590: 589:Gene ontology 586: 582: 570: 565: 561: 554: 549: 546: 544: 540: 532: 527: 516: 512: 508: 504: 500: 496: 492: 488: 484: 480: 479: 476: 472: 467: 464: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 417: 414: 410: 405: 402: 401: 398: 396: 392: 390: 389: 385: 384: 381: 379: 375: 371: 367: 363: 355: 350: 346: 342: 337: 327: 323: 316: 309: 303: 296: 288: 284: 280: 275: 271: 266: 262: 254: 249: 245: 241: 236: 226: 222: 215: 208: 202: 195: 191: 185: 181: 177: 172: 168: 163: 159: 155: 151: 147: 143: 139: 135: 131: 127: 123: 119: 111: 106: 99: 94: 89: 78: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 2375:expanding it 2360: 2345: 2332: 2317: 2302: 2251: 2239: 2199: 2195: 2170: 2166: 2125: 2121: 2086: 2082: 2033: 2029: 1980: 1976: 1947: 1943: 1921:(1): 23–34. 1918: 1914: 1897: 1893: 1847: 1843: 1812: 1808: 1756: 1752: 1742: 1707: 1703: 1693: 1658: 1654: 1644: 1622:(1): 76–84. 1619: 1613: 1607: 1572: 1568: 1558: 1531: 1527: 1517: 1484: 1480: 1474: 1429: 1425: 1415: 1390:10261/154868 1372: 1368: 1362: 1317: 1313: 1303: 1277: 1268: 1259: 1250: 1187: 1171: 1156: 1135: 1131: 1130: 1052:NP_001159406 1049: 1027:NP_001159405 1023:NP_001075424 1020: 993:NM_001165934 990: 968:NM_001165933 964:NM_001081955 961: 937: 918: 892: 873: 847: 828: 808: 803: 393: 386: 352:109,188,955 339:109,116,181 113:External IDs 72: 2285:PDB gallery 2083:J. Neurosci 1950:(1): 12–9. 439:granulocyte 251:65,227,703 238:65,100,812 91:Identifiers 2414:Categories 1809:Genome Res 1245:, May 2017 1224:, May 2017 1200:References 1194:DEP domain 1192:) via the 1176:(although 1152:G proteins 1148:RGS family 455:C1 segment 397:(ortholog) 134:HomoloGene 2365:on human 1710:: 78–85. 1056:NP_035398 1031:NP_003826 997:NM_011268 972:NM_003835 794:Orthologs 643:cytoplasm 142:GeneCards 2216:17698770 2187:15474482 2150:14702087 2113:14614075 2070:12477932 2017:12119397 1964:11485301 1935:10564809 1785:21511947 1734:18073128 1685:19211160 1636:17880927 1599:23246884 1591:17725581 1550:15632124 1509:40755580 1501:15617734 1466:14595021 1407:23943994 1399:11207815 1354:19098104 1241:– 1220:– 1104:Wikidata 773:Sources: 648:membrane 2246:PDBe-KB 2236:UniProt 2130:Bibcode 2104:6741003 2038:Bibcode 1985:Bibcode 1906:9765512 1884:9560279 1852:Bibcode 1831:8889548 1776:3122235 1725:2241663 1676:3394094 1434:Bibcode 1345:2634932 1322:Bibcode 1243:Ensembl 1222:Ensembl 1161:of the 906:UniProt 861:Ensembl 800:Species 779:QuickGO 633:nucleus 419:putamen 372:pattern 230:17q24.1 130:1338824 98:Aliases 2241:O54828 2214:  2185:  2158:953980 2156:  2148:  2122:Nature 2111:  2101:  2068:  2061:139241 2058:  2015:  2008:125004 2005:  1962:  1933:  1904:  1882:  1872:  1829:  1783:  1773:  1732:  1722:  1683:  1673:  1634:  1597:  1589:  1548:  1507:  1499:  1464:  1457:263869 1454:  1405:  1397:  1352:  1342:  1163:retina 1090:search 1088:PubMed 939:O54828 920:O75916 816:Entrez 543:BioGPS 122:604067 2369:is a 2154:S2CID 1875:20264 1595:S2CID 1505:S2CID 1403:S2CID 1182:RGS17 849:19739 809:Mouse 804:Human 775:Amigo 395:Mouse 388:Human 335:Start 270:Mouse 234:Start 167:Human 2371:stub 2363:gene 2333:1fqk 2318:1fqj 2303:1fqi 2234:for 2212:PMID 2183:PMID 2146:PMID 2109:PMID 2066:PMID 2013:PMID 1960:PMID 1931:PMID 1915:Gene 1902:PMID 1880:PMID 1827:PMID 1781:PMID 1730:PMID 1708:1190 1681:PMID 1632:PMID 1587:PMID 1546:PMID 1497:PMID 1462:PMID 1395:PMID 1350:PMID 1190:GNB5 1180:and 1178:RGS4 1140:gene 1136:RGS9 830:8787 378:Bgee 326:Band 287:Chr. 225:Band 184:Chr. 146:RGS9 138:2845 118:OMIM 105:RGS9 75:2PBI 56:RCSB 53:PDBe 22:RGS9 2232:PDB 2204:doi 2200:125 2175:doi 2171:324 2138:doi 2126:427 2099:PMC 2091:doi 2056:PMC 2046:doi 2003:PMC 1993:doi 1952:doi 1948:286 1923:doi 1919:240 1870:PMC 1860:doi 1817:doi 1771:PMC 1761:doi 1757:286 1720:PMC 1712:doi 1671:PMC 1663:doi 1624:doi 1577:doi 1573:103 1536:doi 1532:280 1489:doi 1452:PMC 1442:doi 1430:100 1385:hdl 1377:doi 1340:PMC 1330:doi 1318:105 348:End 247:End 150:OMA 126:MGI 46:PDB 2416:: 2238:: 2210:. 2198:. 2181:. 2169:. 2152:. 2144:. 2136:. 2124:. 2107:. 2097:. 2087:23 2085:. 2081:. 2064:. 2054:. 2044:. 2034:99 2032:. 2028:. 2011:. 2001:. 1991:. 1981:99 1979:. 1975:. 1958:. 1946:. 1929:. 1917:. 1898:54 1896:. 1878:. 1868:. 1858:. 1848:95 1846:. 1842:. 1825:. 1811:. 1807:. 1779:. 1769:. 1755:. 1751:. 1728:. 1718:. 1706:. 1702:. 1679:. 1669:. 1659:30 1657:. 1653:. 1630:. 1620:75 1618:. 1593:. 1585:. 1571:. 1567:. 1544:. 1530:. 1526:. 1503:. 1495:. 1485:48 1483:. 1460:. 1450:. 1440:. 1428:. 1424:. 1401:. 1393:. 1383:. 1373:13 1371:. 1348:. 1338:. 1328:. 1316:. 1312:. 1286:^ 1276:. 1258:. 1229:^ 1208:^ 1169:. 777:/ 354:bp 341:bp 253:bp 240:bp 148:; 144:: 140:; 136:: 132:; 128:: 124:; 120:: 2402:e 2395:t 2388:v 2377:. 2278:e 2271:t 2264:v 2248:. 2218:. 2206:: 2189:. 2177:: 2160:. 2140:: 2132:: 2115:. 2093:: 2072:. 2048:: 2040:: 2019:. 1995:: 1987:: 1966:. 1954:: 1937:. 1925:: 1908:. 1886:. 1862:: 1854:: 1833:. 1819:: 1813:6 1787:. 1763:: 1736:. 1714:: 1687:. 1665:: 1638:. 1626:: 1601:. 1579:: 1552:. 1538:: 1511:. 1491:: 1468:. 1444:: 1436:: 1409:. 1387:: 1379:: 1356:. 1332:: 1324:: 1297:. 1280:. 1262:. 272:) 169:) 152::

Index


PDB
PDBe
RCSB
2PBI
Aliases
RGS9
OMIM
604067
MGI
1338824
HomoloGene
2845
GeneCards
RGS9
OMA
RGS9 - orthologs
Human
Chromosome 17 (human)
Chr.
Chromosome 17 (human)
Chromosome 17 (human)
Genomic location for RGS9
Genomic location for RGS9
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.

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