370:, to protect human mental privacy, identity, agency and equal access to cognitive enhancement and also prevent algorithm biases. In 2018, professor Yuste was awarded the Tällberg/Eliasson Foundation prize due to his commitment to exploring the ethical implications of using emerging AI in the field of neurotechnology. This prize, which is "awarded annually to outstanding leaders who demonstrate the willingness and capacity to address the complexity of 21st-century challenges in innovative, risk-taking, and ethical ways, and whose work is global in aspiration or implication and is rooted in universal values" is a substantial honor.
34:
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and its
Fundación Jiménez Díaz Hospital (1982–1987). Finding the treatment and understanding of mental diseases as "primitive", Yuste decided that instead of practicing medicine he would work on laying the scientific basis for future treatments through basic biological research. He worked for two
366:
single-neuron resolution that would be made available at observatory-like centers to the scientific community. Yuste has also spearheaded the development of ethical guidelines for neurotechnology and AI (ref
Goering 2016 and Yuste 2017), proposing that five new NeuroRights be added to the
365:
that now funds neuroscience research in over 500 laboratories and is slated to last until 2025. Yuste has warned against spreading the funds of the initiative too thin and argued that a focused effort is required to develop the technologies needed for large-scale, real-time brain imaging with
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channels are activated, thus allowing Ca ions to enter the cell. If one brings a calcium-sensitive dye into neurons in the brain, one can detect under the microscope when a neuron is active. The technique is detailed in Yuste's doctoral thesis
802:
487:
Ikegaya, Yuji; Aaron, Gloster; Cossart, Rosa; Aronov, Dmitriy; Lampl, Ilan; Ferster, David; Yuste, Rafael (2004). "Synfire Chains and
Cortical Songs: Temporal Modules of Cortical Activity". Science.
227:. There he developed the calcium imaging technique to measure and monitor the activity of neuronal populations. The technique is based on the fact that when an electric signal depolarizes a
423:
309:, Spain. In addition, he has served, or currently serves, on the scientific advisory board of several institutes, foundations, and companies in the US, Spain, and Israel, such as the
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Alivisatos, A. P.; Chun, M.; Church, G. M.; Greenspan, R. J.; Roukes, M. L.; Yuste, R. (2012). "The Brain
Activity Map Project and the Challenge of Functional Connectomics". Neuron.
477:
Carrillo-Reid, L., Han, S., Yang, W., Akrouh, A., and Yuste, R. (2019). Controlling visually-guided behavior by holographic activation of cortical ensembles. Cell 178, 447-457..
341:
In 2011 at a meeting with funding agencies, Yuste proposed the goal of developing technologies to "record every spike from every neuron" and then co-authored together with
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Yuste, Rafael; Bonhoeffer, Tobias (2001). "Morphological changes in dendritic spines associated with long-term synaptic plasticity". Annual Review of
Neuroscience.
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at
Columbia University and since 2014 the director of Columbia's Neurotechnology Center. Since 2019 he has been the Director of the NeuroRights Initiative.
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In 2019 Yuste was appointed
Ikerbasque Research Professor and since then he works several weeks per year at the Donostia International Physics Center in
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Carrillo-Reid, L., Yang, W., Bando, Y., Peterka, D. and Yuste, R. (2016). Imprinting and recalling cortical ensembles. Science 353: 691-694.
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Yuste, Rafael; Goering, Sara; Agüera y Arcas, Blaise; et al. (2017-11-09). "Four ethical priorities for neurotechnologies and AI". Nature.
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a white paper to elaborate this idea as a large-scale scientific project (then called the "Brain
Activity Map Project") modeled on the
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314:
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1318:"Rafael Yuste awarded DOD's highly-competitive Vannevar Bush Faculty Fellowship | Columbia University : Biological Sciences"
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As of 2021 Yuste has published more than 260 papers. According to Google
Scholar he has been cited more than 38,000 times for an
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Cossart, R., Aronov, D. and Yuste, R. (2003). Attractor dynamics of network UP states in the neocortex. Nature 423: 283-8
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799:"Rafael Yuste: "La misma tecnología que curará la esquizofrenia servirá para manipular la mente" (interview with Yuste)"
292:
as a random circuit using novel two-photon imaging methods in a large-scale study of the mouse cortical microcircuit.
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Yuste, Rafael; Denk, Winfried (1995). "Dendritic spines as basic functional units of neuronal integration". Nature.
325:'s Conte Center (2013-2017). Yuste has served on the editorial board of numerous professional journals, among them
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where he worked four years as a postdoc, combining calcium imaging with the two-photon microscope invented by
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Yuste, R., Peinado, A. and Katz, L. C. (1992). Neuronal domains in developing neocortex. Science 257: 665-669
208:
274:, obtaining tenure in 2002 and becoming a full professor in 2006. Since 2004 he is also co-director of the
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827:"Columbia Establishes NeuroTechnology Center, Latest Step in Commitment to Interdisciplinary Neuroscience"
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Yuste, R. (2015). From the neuron doctrine to neural networks. Nature
Reviews Neuroscience 16: 487-497
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Yuste, Rafael; Church, George M. (2014). "The new century of the brain" (pdf). Scientific American.
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and, through discussions with John Hopfield and David Tank, becoming convinced of the importance of
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240:(1992), which was directed by Wiesel and Katz. It has since become one of the technical pillars of
215:'s government made him look for PhD opportunities in the United States. In 1987 he was admitted to
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2002 Mayor's Young Investigator Award for Excellence in Science and Technology, New York City
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Yang, Weijian; Yuste, Rafael (2017). "In vivo imaging of neural activity". Nature Methods.
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276:
1293:"El neurobiólogo Rafael Yuste inaugurará el jueves las celebraciones del Instituto Cajal"
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In 1996 Yuste became an assistant professor in the Department of Biological Sciences at
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1985 Young Researcher Award, National Research Council, Cajal Institute, Madrid, Spain
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241:
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263:(rather than just single neurons) for understanding the functioning of the brain (
703:"Obama presenta con el español Rafael Yuste su proyecto para estudiar el cerebro"
200:
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with a grant of US$ 2.5 million to fund research to test the hypothesis of the
1230:
887:"Dos millones de euros para el español que trazará el mapa del cerebro humano"
814:
A mí en Inglaterra me pillaron los recortes de la Thatcher y terminé en EEUU .
248:
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778:"El científico español que convenció a Obama de descifrar el cerebro humano"
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Los Tónicos de la Voluntad: Reglas y consejos sobre investigación científica
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Optical studies of calcium dynamics in developing neocortical neurons
1053:"TED talk about the beginning and importance of the BRAIN initiative"
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Optical studies of calcium dynamics in developing neocortical neurons
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Yuste's interest in neuroscience arose early, inspired by books like
159:
118:
1257:
1279:"UWIN Visiting Professor wins Eliasson Global Leadership Prize"
192:
The Tonics of the Will: Rules and Advice on Scientific Research
1170:"Rafael yuste - Tällberg / Eliasson Global Leadership Prize"
443:
2015 Corresponding Member Spanish Royal Academy of Medicine
194:) and supported by his parents. He studied medicine at the
862:"FUNCTIONAL CONNECTOMICS OF THE NEOCORTICAL MICROCIRCUIT"
727:"The Origins of the BRAIN Initiative: A Personal Journey"
651:"The Origins of the BRAIN Initiative: A Personal Journey"
313:, BIOFISIKA, a joint Biophysics Research Centre of the
1359:"Rafael Yuste in the "Neurotree" (Academic Genealogy)"
82:
Universidad Autónoma de Madrid, Rockefeller University
388:
1996 Klingenstein Foundation Young Investigator Award
940:"¿Qué tipo de humanidad queremos tras el COVID-19?"
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2012 Named “Five to Watch in 2013”, Nature Magazine
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Neuroscientist and neurorights advocate (born 1963)
997:"El mayor proyecto neurocientífico de la Historia"
801:(in Spanish). La Información. 2013. Archived from
170:announced in 2013. He is currently a professor at
1149:"Obama decepciona a 'su' neurocientífico español"
848:"Professor Rafael Yuste | Neurorights Initiative"
912:"PubMed search results Yuste R[Author]"
446:2017 Alumni Prize, Universidad Autónoma Madrid
434:2015 Premio Lección Conmemorativa Jiménez Díaz
428:2014 Lenfest Faculty Award Columbia University
970:. Universidad de Cuenca. 2017. Archived from
548:Yuste, R. (2010). Dendritic Spines. MIT Press
394:1997 EJLB Foundation Young Investigator Award
90:calcium imaging technique, brain activity map
8:
1013:(in Spanish). Fundación GADEA por la Ciencia
391:1997 Basil O'Connor Young Investigator Award
199:summers (1985/86) in the laboratory of the
1258:"José Luis Sanz nuevo Académico Numerario"
1231:"XLVII Lección Conmemorativa Jiménez Díaz"
1191:"Tallberg/Eliasson Global Leadership Goal"
32:
18:
1098:Yuste, Rafael; Church, George M. (2014).
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1260:(in Spanish). Real Academia de Ciencias
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337:Brain Activity Map and BRAIN Initiative
219:and joined the group of Nobel laureate
1406:Autonomous University of Madrid alumni
455:2018 Eliasson Global Leadership Prize
368:Universal Declaration of Human Rights
7:
1411:Members of the Royal Spanish Academy
1209:Arnold and Mabel Beckman Foundation
1032:"People: SCIENTIFIC ADVISORY BOARD"
594::10.1038/scientificamerican0314-38.
452:2017 “Hero” Award, Fundación Querer
1345:"Yuste Lab at Columbia University"
1151:(in Spanish). El Mundo. 2014-02-18
14:
1127:10.1038/scientificamerican0314-38
561::10.1146/annurev.neuro.24.1.1071.
406:Beckman Young Investigators Award
357:. Two years later then president
315:Spanish National Research Council
166:and one of the initiators of the
1229:Universidad Autónoma de Madrid.
461:2020 Vannevar Bush Faculty Award
439:Spanish Royal Academy of Science
319:University of the Basque Country
135:Torsten Wiesel, Lawrence C. Katz
1441:21st-century Spanish scientists
1436:20th-century Spanish scientists
416:2002 Young Investigator Award,
333:(associate editor since 1998).
1100:"The new century of the brain"
607::10.1016/j.neuron.2012.06.006.
410:2001 John Merck Scholars Award
399:Epilepsy Foundation of America
329:(chief editor, 2006-2013) and
196:Universidad Autónoma de Madrid
1:
1011:"Scientific Advisory Council"
995:Pere Estupinya (2013-03-11).
928:. Google Scholar. 2021-06-05.
780:(in Spanish). BBC. 2013-04-04
631:. Universidad de Cuenca. 2017
701:María Ramírez (2013-04-02).
424:NIH Director's Pioneer Award
327:Frontiers in Neural Circuits
286:NIH Director's Pioneer Award
1421:21st-century Spanish people
1416:20th-century Spanish people
1396:Columbia University faculty
284:In 2013 Yuste received the
1457:
1299:. Europa Press. 2020-02-19
747:10.1016/j.cell.2017.10.026
671:10.1016/j.cell.2017.10.026
437:2015 Corresponding Member
374:Selected honors and awards
946:(in Spanish). 26 May 2020
864:. nih.gov. Archived from
495::10.1126/science.1093173.
384:Sloan Research Fellowship
211:, but the budget cuts of
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1374:publications indexed by
1322:www.biology.columbia.edu
449:2016 Telva Science Prize
418:Society for Neuroscience
401:Young Investigator Award
162:) is a Spanish–American
158:(born April 25, 1963 in
1391:Spanish neuroscientists
349:, Ralph Greenspan, and
209:University of Cambridge
38:Yuste at his microscope
1401:Sloan Research Fellows
999:(in Spanish). El País.
217:Rockefeller University
184:Santiago Ramón y Cajal
725:Rafael Yuste (2017).
649:Rafael Yuste (2017).
567:Policy and commentary
466:Selected publications
1074:"The observer corps"
538::10.1038/nmeth.4230.
355:Human Genome Project
247:Yuste then moved to
1119:2014SciAm.310c..38Y
1107:Scientific American
272:Columbia University
172:Columbia University
113:Columbia University
513::10.1038/375682a0.
458:2020 Cajal Diploma
1297:www.infosalus.com
965:"CV Rafael Yuste"
626:"CV Rafael Yuste"
581::10.1038/551159a.
577:(7679): 159–163.
491:(5670): 559–564.
361:announced the US
279:for Brain Science
253:Bell Laboratories
213:Margaret Thatcher
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131:Doctoral advisors
96:Scientific career
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225:Lawrence C. Katz
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1372:Rafael Yuste
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1301:. Retrieved
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