126:
hypnotic wears off. Rebound phenomena do not necessarily only occur on discontinuation of a prescribed dosage. Another example is early morning rebound insomnia which may occur when a rapidly eliminated hypnotic wears off which leads to rebounding awakeness forcing the person to become wide awake
66:
that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage. In the case of re-emergence, the severity of the symptoms is often worse than pretreatment levels.
49:
that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage. In the case of re-emergence, the severity of the symptoms is often worse than pretreatment levels.
139:, due to its selectivity for type1 benzodiazepine receptors and long half-life, does not cause daytime anxiety rebound effects during treatment, showing that half-life is very important for determining whether a nighttime
143:
will cause next-day rebound withdrawal effects or not. Daytime rebound effects are not necessarily mild but can sometimes produce quite marked psychiatric and psychological disturbances.
92:
on its effects in order to fall asleep. Therefore, when a person has stopped taking the medication and is 'rebounding' from its effects, they may experience insomnia as a symptom of
1084:
291:
experienced a rebound. The cause of the rebound is unclear however, since around a third of people with COVID-19 experience a symptom rebound regardless of treatment.
814:
Fernandez, Hubert H.; Martha E. Trieschmann; Michael S. Okun (3 Aug 2004). "Rebound psychosis: Effect of discontinuation of antipsychotics in
Parkinson's disease".
171:
and a return of ADHD symptoms but in a temporarily exaggerated form. Up to a third of ADHD children experience a rebound effect when methylphenidate is withdrawn.
466:
Lee A, Lader M (January 1988). "Tolerance and rebound during and after short-term administration of quazepam, triazolam and placebo to healthy human volunteers".
859:"Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse"
306:
can cause a much more severe case of the psoriasis to develop. Therefore, withdrawal should be gradual, until very little actual medication is being applied.
1764:
1634:
1047:
972:"Understanding the risk of using medications for attention deficit hyperactivity disorder with respect to physical growth and cardiovascular function"
1077:
775:"Persistent tardive rebound panic disorder, rebound anxiety and insomnia following paroxetine withdrawal: a review of rebound-withdrawal phenomena"
287:
were published. In May, CDC even issued a health alert informing physicians about "Paxlovid rebounds", which received attention when US president
1907:
184:
96:. Occasionally, this insomnia may be worse than the insomnia the drug was intended to treat. Common medicines known to cause this problem are
1431:
653:
Rosenfeld AA (February 1979). "Depression and psychotic regression following prolonged methylphenidate use and withdrawal: case report".
1070:
1938:
1785:
1234:
544:
Hilbert JM, Battista D (September 1991). "Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics".
119:
858:
1487:
372:
731:
1540:
1406:
1497:
1389:
610:
Garland EJ (1998). "Pharmacotherapy of adolescent attention deficit hyperactivity disorder: challenges, choices and caveats".
1971:
1966:
1891:
1546:
1140:
1718:
423:
Kales A, Soldatos CR, Bixler EO, Kales JD (April 1983). "Early morning insomnia with rapidly eliminated benzodiazepines".
31:
1567:
1400:
1365:
774:
689:
1931:
1795:
1724:
1712:
1370:
1124:
127:
before he or she has had a full night's sleep. One drug which seems to be commonly associated with these problems is
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1205:
1159:
1110:
1096:
320:
1801:
1595:
1360:
1324:
1258:
1242:
1195:
1168:
732:"Effects of stimulants on the continuous performance test (CPT): implications for CPT use and interpretation"
1780:
1412:
1266:
340:
315:
216:
276:
from painkillers when the dose is lowered, the medication wears off, or the drug is abruptly discontinued.
88:
substances taken to relieve primary insomnia. Regular use of these substances can cause a person to become
1866:
1827:
1658:
1556:
1436:
1376:
1355:
1314:
1303:
1247:
1150:
1115:
257:
131:, due to its high potency and ultra short half life, but these effects can occur with other short-acting
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1535:
1345:
1284:
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1817:
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89:
1664:
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1395:
894:
839:
635:
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526:
388:
Lader, Malcolm (January 1994). "Anxiety or depression during withdrawal of hypnotic treatments".
902:
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Daytime rebound effects of anxiety, metallic taste, perceptual disturbances which are typical
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1524:
1155:
1129:
335:
156:
109:
93:
17:
567:
Adam K; Oswald I (May 1989). "Can a rapidly-eliminated hypnotic cause daytime anxiety?".
436:
1772:
1462:
1218:
996:
971:
514:
361:
295:
269:
180:
132:
123:
115:
Rebound depression may appear to arise in patients previously free of such an illness.
59:
30:
This article is about the pharmacological term. For the energy conservation term, see
1960:
1119:
941:
874:
747:
479:
401:
220:
212:
192:
843:
639:
596:
530:
1618:
898:
112:
and which are prescribed to people having difficulties falling or staying asleep.
1858:
1809:
248:
97:
623:
1945:
1502:
1456:
987:
236:
152:
105:
926:"Rebound hypertension after discontinuation of transdermal clonidine therapy"
882:
797:
1839:
709:
444:
303:
288:
232:
128:
1032:
1005:
890:
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755:
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Sudden and severe emergence or re-emergence of psychosis may appear when
1912:
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674:
284:
280:
200:
140:
136:
101:
85:
81:
1878:
1579:
196:
63:
46:
827:
1691:
1048:"Covid rebound can happen even in people who haven't taken Paxlovid"
231:
Rebound hypertension, above pre-treatment level, was observed after
279:
In 2022, reports of viral RNA and symptom rebound in people with
501:
Kales A (1990). "Quazepam: hypnotic efficacy and side effects".
1066:
1019:
Maizels M (December 2004). "The patient with daily headaches".
924:
Metz, Stewart; Catherine Klein; Nancy Morton (January 1987).
773:
Bhanji NH, Chouinard G, Kolivakis T, Margolese HC (2006).
62:
rebound phenomenon, is the emergence or re-emergence of
1923:
1877:
1838:
1747:
1690:
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1617:
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1523:
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1344:
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1257:
1233:
1226:
1217:
1183:
1103:
730:Riccio CA, Waldrop JJ, Reynolds CR, Lowe P (2001).
360:
1630:Acute intoxication from hallucinogens (bad trip)
1078:
8:
122:can occur the next day after a short-acting
1635:Hallucinogen persisting perception disorder
1230:
1223:
1085:
1071:
1063:
359:Reber, Arthur S.; Reber, Emily S. (2001).
995:
84:that occurs following discontinuation of
688:Smucker WD, Hedayat M (September 2001).
1765:Kindling (sedative–hypnotic withdrawal)
351:
1908:Chronic solvent-induced encephalopathy
869:(1). John Wiley & Sons A/S: 3–13.
45:, is the emergence or re-emergence of
1432:Alcohol-induced respiratory reactions
7:
857:Moncrieff, Joanna (23 March 2006).
294:Abrupt withdrawal of highly potent
1939:Anabolic-androgenic steroids abuse
1568:Synthetic cannabinoid use disorder
690:"Evaluation and treatment of ADHD"
515:10.1002/j.1875-9114.1990.tb02545.x
120:benzodiazepine withdrawal symptoms
25:
1488:Caffeine-induced anxiety disorder
976:Child Adolesc Psychiatr Clin N Am
390:Journal of Psychosomatic Research
1541:Cannabinoid hyperemesis syndrome
930:The American Journal of Medicine
875:10.1111/j.1600-0447.2006.00787.x
748:10.1176/appi.neuropsych.13.3.326
480:10.1097/00004850-198801000-00002
1498:Caffeine-induced sleep disorder
1390:Fetal alcohol spectrum disorder
736:J Neuropsychiatry Clin Neurosci
1892:Sudden sniffing death syndrome
1547:Intravenous marijuana syndrome
1141:Post-acute-withdrawal syndrome
863:Acta Psychiatrica Scandinavica
1:
1719:Opioid-induced endocrinopathy
1046:Reynolds Lewis (2022-08-02).
32:Rebound effect (conservation)
1932:Anabolic-androgenic steroids
1459:(alcohol use disorder (AUD))
1401:Positional alcohol nystagmus
1366:Alcohol-related brain damage
942:10.1016/0002-9343(87)90371-8
612:J. Psychopharmacol. (Oxford)
509:(1): 1–10, discussion 10–2.
402:10.1016/0022-3999(94)90142-2
1796:Benzodiazepine use disorder
1725:Opioid-induced constipation
1713:Opioid-induced hyperalgesia
1407:Wernicke–Korsakoff syndrome
1371:Alcohol withdrawal syndrome
1160:Substance-related disorders
1125:Substance-induced psychosis
1097:substance-related disorders
1988:
1493:Caffeine-induced psychosis
1424:Respiratory tract diseases
1409:(WKS, Korsakoff psychosis)
1206:Combined drug intoxication
624:10.1177/026988119801200410
321:Supersensitivity psychosis
29:
18:Rebound withdrawal effects
1802:Benzodiazepine dependence
1786:Benzodiazepine withdrawal
1596:Prenatal cocaine exposure
1259:Gastrointestinal diseases
988:10.1016/j.chc.2007.11.010
970:Vitiello B (April 2008).
396:(Supplement 1): 113–123.
227:Alpha-2 adrenergic agents
1361:Alcoholic polyneuropathy
1325:Alcohol-related dementia
1243:Alcoholic cardiomyopathy
1196:Polysubstance dependence
1169:Psychological dependence
468:Int Clin Psychopharmacol
363:Dictionary of Psychology
1781:Benzodiazepine overdose
1413:Wernicke encephalopathy
1267:Alcoholic liver disease
1235:Cardiovascular diseases
445:10.1126/science.6131538
341:Unintended consequences
316:Disuse supersensitivity
252:) can lead to constant
58:The rebound effect, or
1867:Amphetamine dependence
1828:Barbiturate dependence
1659:Green Tobacco Sickness
1557:Amotivational syndrome
1437:Alcoholic lung disease
1377:Alcoholic hallucinosis
1356:Alcoholic hallucinosis
1304:Alcoholic ketoacidosis
1248:Alcohol flush reaction
1116:Substance intoxication
581:10.1055/s-2007-1014592
258:rhinitis medicamentosa
1972:Psychiatric diagnosis
1967:Clinical pharmacology
1562:Cannabis use disorder
1285:Auto-brewery syndrome
667:10.1176/ajp.136.2.226
367:. Penguin Reference.
244:topical decongestants
151:Rebound effects from
1818:Barbiturate overdose
1591:Cocaine intoxication
1331:Alcohol intoxication
1173:Substance dependence
782:Can J Clin Pharmacol
242:Continuous usage of
187:, can cause rebound
80:Rebound insomnia is
27:Pharmacological term
1851:Stimulant psychosis
1736:Opioid use disorder
1680:Nicotine dependence
1670:Nicotine withdrawal
1513:Caffeine dependence
1273:Alcoholic hepatitis
1165:Physical dependence
1136:Neonatal withdrawal
437:1983Sci...220...95K
326:Physical dependence
268:Another example of
203:when discontinued.
165:stimulant psychosis
1665:Nicotine poisoning
1607:Cocaine dependence
1536:Cannabis arteritis
1396:Korsakoff syndrome
1296:Endocrine diseases
816:Movement Disorders
569:Pharmacopsychiatry
548:. 52 Suppl: 21–6.
76:Sedative hypnotics
43:rebound phenomenon
1954:
1953:
1708:Opioid withdrawal
1471:
1470:
1445:
1444:
982:(2): 459–74, xi.
905:on 5 January 2013
828:10.1002/mds.20260
546:J Clin Psychiatry
264:Other medications
239:discontinuation.
161:dextroamphetamine
16:(Redirected from
1979:
1898:Toluene toxicity
1382:Delirium tremens
1278:Zieve's syndrome
1231:
1224:
1087:
1080:
1073:
1064:
1058:
1057:
1055:
1054:
1043:
1037:
1036:
1027:(12): 2299–306.
1021:Am Fam Physician
1016:
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901:. Archived from
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796:. Archived from
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758:. Archived from
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708:. Archived from
694:Am Fam Physician
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331:Rebound headache
274:rebound headache
254:nasal congestion
21:
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1703:Opioid overdose
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1317:system diseases
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1156:Substance abuse
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336:Drug withdrawal
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296:corticosteroids
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181:antidepressants
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175:Antidepressants
157:methylphenidate
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110:benzodiazepines
78:
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35:
28:
23:
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11:
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1463:Binge drinking
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849:
822:(1): 104–105.
806:
803:on 2006-04-12.
765:
762:on 2012-07-14.
722:
680:
645:
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536:
493:
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431:(4592): 95–7.
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270:pharmaceutical
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213:antipsychotics
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207:Antipsychotics
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133:hypnotic drugs
124:benzodiazepine
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60:pharmaceutical
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39:rebound effect
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1188:
1186:substance use
1182:
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1120:Drug overdose
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1094:Psychoactive
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1810:barbiturate
256:, known as
106:anxiolytics
98:eszopiclone
1961:Categories
1840:Stimulants
1503:Caffeinism
1457:Alcoholism
1130:Withdrawal
1053:2022-08-04
955:5 December
716:2009-04-27
347:References
300:clobetasol
298:, such as
237:guanfacine
189:depression
169:depression
153:stimulants
147:Stimulants
94:withdrawal
54:Definition
1946:Chocolate
1348:disorders
883:1600-0447
304:psoriasis
289:Joe Biden
233:clonidine
129:triazolam
90:dependent
1879:Volatile
1754:hypnotic
1749:Sedative
1648:Nicotine
1525:Cannabis
1477:Caffeine
1336:Hangover
1184:Combined
1033:15617293
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310:See also
285:Paxlovid
281:COVID-19
217:switched
201:insomnia
163:include
155:such as
141:hypnotic
137:Quazepam
108:such as
102:zolpidem
86:sedative
82:insomnia
71:Examples
64:symptoms
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1924:Related
1881:solvent
1692:Opioids
1580:Cocaine
1373:(AWS):
1315:Nervous
1269:(ALD):
1219:Alcohol
1104:General
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433:Bibcode
425:Science
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197:anxiety
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199:, and
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1738:(OUD)
1727:(OIC)
1721:(OIE)
1715:(OIH)
1661:(GTS)
1598:(PCE)
1564:(CUD)
1543:(CHS)
1403:(PAN)
1384:(DTs)
1327:(ARD)
1306:(AKA)
1287:(ABS)
1250:(AFR)
1208:(CDI)
909:3 May
895:S2CID
840:S2CID
801:(PDF)
778:(PDF)
636:S2CID
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527:S2CID
185:SSRIs
179:Many
41:, or
1904:SUD
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946:PMID
911:2009
887:PMID
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832:PMID
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671:PMID
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585:PMID
550:PMID
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484:PMID
449:PMID
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369:ISBN
302:for
215:are
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