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The contralateral kidney often undergoes hypertrophy. This is believed to be a compensatory mechanism to the non-functional MCDK. About 90% of patients with an MCDK will have contralateral hypertrophy into adulthood. The impact of contralateral hypertrophy on long-term renal outcomes is unknown.
152:
When a diagnosis of multicystic kidney is made in utero by ultrasound, the disease is found to be bilateral in many cases. Those with bilateral disease often have other severe deformities or polysystemic malformation syndromes. In bilateral cases, the newborn has the classic characteristic of
248:
analysis of urine in individuals with probable multicystic dysplastic kidney should be done. One meta-analysis demonstrated that unilateral MCDK occurs more frequently in males and the greater percentage of MCDK occur on the left side of the body.
801:
600:
Schreuder, M. F.; Westland, R.; Van Wijk, J. A. E. (2009). "Unilateral multicystic dysplastic kidney: A meta-analysis of observational studies on the incidence, associated urinary tract malformations and the contralateral kidney".
374:
Chang, Ling-Wei; Chang, Fong-Ming; Chang, Chiung-Hsin; Yu, Chen-Hsiang; Cheng, Yueh-Chin; Chen, Hsi-Yao (2002). "Prenatal diagnosis of fetal multicystic dysplastic kidney with two-dimensional and three-dimensional ultrasound".
924:
168:
is seen even more often, in 18% to 43% of infants. Because the high incidence of reflux, voiding cystourethrography usually has been considered advisable in all newborns with a multicystic kidney.
261:
are generally taken to ensure the healthy kidney is functioning properly and that the unhealthy kidney is not causing adverse effects. In severe cases MCDK can lead to neonatal fatality (in
917:
910:
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1853:
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510:
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28:
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208:. Some mutations in genes associated with renal dysplasia (in syndromes) have been determined. The mutations in question occur at
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The bilateral condition is incompatible with survival, as the contralateral system frequently is abnormal as well. Contralateral
2006:
1878:
1312:
1858:
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136:. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal
1911:
1138:
992:
553:
Gaither, Thomas W.; Patel, Ankur; Patel, Chandni; Chuang, Kai-wen; Cohen, Ronald A.; Baskin, Laurence S. (2018).
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of MCDK is estimated to be 1 in every 4,000 live births, making it rare in terms of the general population.
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MCDK is not treatable. However, the patient is observed periodically for the first few years during which
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Van Eijk, L.; Cohen-Overbeek, T. E.; Den
Hollander, N. S.; Nijman, J. M.; Wladimiroff, J. W. (2002).
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555:"Natural History of Contralateral Hypertrophy in Patients with Multicystic Dysplastic Kidneys"
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This article is about kidney dysplasia in humans. For kidney dysplasia in dogs and cats, see
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1016:
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Stevenson, Roger E.; Hall, Judith G.; Everman, David B.; Solomon, Benjamin D. (2015-10-16).
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Practical Renal
Pathology, A Diagnostic Approach: A Volume in the Pattern Recognition Series
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2016:
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examination before birth. Mean age at the time of antenatal diagnosis is about 28 weeks A
154:
34:
This article is about MCDK, a congenital malformation. For the genetic disorder PCKD, see
432:
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883:
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The mechanism of multicystic dysplastic kidney is a result of an abnormal induction of
164:
obstruction is found in 3% to 12% of infants with multicystic kidney and contralateral
141:
388:
184:, which in turn may affect the digestive tract, nervous system, or other areas of the
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cases the prognosis might be better (it would be dependent on associated anomalies).
185:
850:
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738:"Unilateral multicystic dysplastic kidney: A combined pre- and postnatal assessment"
1996:
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Al-Khaldi, N.; Watson, A. R.; Zuccollo, J.; Twining, P.; Rose, D. H. (1994).
188:. If the mother had been taking certain prescription drugs such as those for
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Atlas of
Ultrasound in Obstetrics and Gynecology: A Multimedia Reference
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In regard to the epidemiology of multicystic dysplasia kidney, the
695:"Outcome of antenatally detected cystic dysplastic kidney disease"
231:
217:
213:
209:
176:
The cause of multicystic dysplastic kidney can be attributed to
1212:
906:
449:
Seseke, F. (2003). "Clinical
Aspects of Paediatric Urology".
1208:
128:) is a condition that results from the malformation of the
204:. This could be a result of a formation difficulty of the
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669:. Lippincott Williams & Wilkins. p. 439.
343:. Lippincott Williams & Wilkins. p. 152.
499:Lager, Donna J.; Abrahams, Neil (2012-11-07).
192:, this may be a precipitating factor as well.
1224:
918:
337:Doubilet, Peter M.; Benson, Carol B. (2003).
220:gene is also thought to play a role in MCDK.
180:. Renal dysplasia can be a consequence of a
8:
322:: CS1 maint: numeric names: authors list (
1513:Reproductive endocrinology and infertility
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951:
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911:
903:
784:
84:
43:
1854:Bachelor of Medicine, Bachelor of Surgery
753:
718:
639:Human Malformations and Related Anomalies
299:"Orphanet: Multicystic dysplastic kidney"
216:genes (branchio-oto-renal syndrome). The
642:. Oxford University Press. p. 800.
505:. Elsevier Health Sciences. p. 27.
69:Diagram of multicystic dysplastic kidney
742:Ultrasound in Obstetrics and Gynecology
369:
367:
289:
2048:Congenital disorders of urinary system
410:
408:
406:
315:
236:Ultrasound Scan -Vesicoureteral reflux
524:
522:
433:Multicystic Dysplastic Kidney Imaging
7:
1992:
1753:Physical medicine and rehabilitation
377:Ultrasound in Medicine & Biology
297:RESERVED, INSERM US14-- ALL RIGHTS.
97:Due to atresia at 10 weeks gestation
2002:
663:Schwartz, M. William (2012-01-01).
603:Nephrology Dialysis Transplantation
1889:Medical Scientist Training Program
25:
140:disease, and it is a cause of an
29:Familial renal disease in animals
2021:
2011:
2001:
1991:
1982:
1981:
876:
755:10.1046/j.0960-7692.2001.00497.x
699:Archives of Disease in Childhood
60:
2022:
1879:Doctor of Osteopathic Medicine
1313:Oral and maxillofacial surgery
937:malformations and deformations
666:The 5 Minute Pediatric Consult
1:
1003:Multicystic dysplastic kidney
894:Multicystic dysplastic kidney
451:Imaging in Paediatric Urology
389:10.1016/s0301-5629(02)00535-5
240:MCDK is usually diagnosed by
122:Multicystic dysplastic kidney
47:Multicystic dysplastic kidney
1859:Bachelor of Medical Sciences
1626:Neurosurgical anesthesiology
459:10.1007/978-3-642-55785-9_1
416:Multicystic Renal Dysplasia
55:Multicystic renal dysplasia
2069:
571:10.1016/j.juro.2017.06.075
33:
26:
1977:
1139:Penoscrotal transposition
1134:Posterior urethral valves
993:Polycystic kidney disease
483:Potter Syndrome~treatment
68:
59:
36:Polycystic kidney disease
1813:Transplantation medicine
1704:Clinical neurophysiology
1621:Obstetric anesthesiology
1541:Interventional radiology
1301:Digestive system surgery
1684:Intensive care medicine
1658:Mass gathering medicine
1503:Maternal–fetal medicine
1008:Medullary sponge kidney
115:Nephrectomy, if needed
1276:Cardiothoracic surgery
237:
202:metanephric mesenchyme
162:ureteropelvic junction
1927:Personalized medicine
1786:Reproductive medicine
1711:Occupational medicine
1665:Evolutionary medicine
979:Papillorenal syndrome
235:
166:vesicoureteral reflux
1947:Traditional medicine
1907:Alternative medicine
1774:Addiction psychiatry
1588:Transfusion medicine
1583:Medical microbiology
1498:Gynecologic oncology
1350:Reproductive surgery
1159:Prune belly syndrome
1032:Supernumerary kidney
711:10.1136/adc.70.6.520
1969:History of medicine
1952:Veterinary medicine
1759:Preventive medicine
1611:Adolescent medicine
1453:Infectious diseases
265:cases), however in
1917:Molecular oncology
1874:Doctor of Medicine
1864:Master of Medicine
1781:Radiation oncology
1653:Emergency medicine
1606:Addiction medicine
1573:Clinical chemistry
1568:Clinical pathology
1360:Transplant surgery
1318:Orthopedic surgery
1296:Colorectal surgery
837:External resources
615:10.1093/ndt/gfn777
559:Journal of Urology
530:"Kidney Dysplasia"
238:
148:Signs and symptoms
2035:
2034:
1869:Master of Surgery
1833:
1832:
1818:Tropical medicine
1764:Prison healthcare
1679:Hospital medicine
1643:Disaster medicine
1633:Aviation medicine
1448:Hospital medicine
1355:Surgical oncology
1340:Pediatric surgery
1334:
1281:Endocrine surgery
1206:
1205:
1202:
1201:
1147:
1146:
1106:Bladder exstrophy
1085:
1084:
1077:Duplicated ureter
871:
870:
534:www.niddk.nih.gov
468:978-3-642-62803-0
453:. pp. 1–67.
155:Potter's syndrome
134:fetal development
119:
118:
103:Diagnostic method
41:Medical condition
16:(Redirected from
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2025:
2024:
2015:
2005:
2004:
1995:
1994:
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1984:
1689:Medical genetics
1674:General practice
1551:Nuclear medicine
1426:Gastroenterology
1382:Vascular surgery
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1027:Nephronophthisis
1017:Horseshoe kidney
969:Renal hypoplasia
952:
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609:(6): 1810–1818.
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182:genetic syndrome
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80:Medical genetics
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1973:
1962:Chief physician
1895:
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1823:Travel medicine
1808:Sports medicine
1791:Sexual medicine
1731:Palliative care
1726:Pain management
1670:Family medicine
1648:Diving medicine
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1345:Plastic surgery
1291:General surgery
1271:Cardiac surgery
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1189:Urachal fistula
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998:Meckel syndrome
974:Potter sequence
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817:Q61.40-Q61.41)
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788:Classification
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780:External links
778:
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748:(2): 180–183.
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565:(1): 280–286.
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512:978-1455737864
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1578:Cytopathology
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1518:Urogynecology
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1248:Specialties
1129:Hypospadias
259:ultrasounds
246:microscopic
107:Ultrasound
52:Other names
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1769:Psychiatry
1755:(PM&R)
1748:Phlebology
1736:Pediatrics
1563:Anatomical
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539:2015-11-24
285:References
267:unilateral
242:ultrasound
1957:Physician
1841:education
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1411:Angiology
1375:Andrology
1168:Vestigial
948:Abdominal
851:radio/458
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488:eMedicine
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356:2 January
279:incidence
263:bilateral
253:Treatment
228:Diagnosis
112:Treatment
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178:genetics
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