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Robert Williams (English chemist)

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William's work in pure inorganic chemistry led to a two-volume textbook of inorganic chemistry, written with Courtenay Phillips, He became increasingly interested in enzyme catalysis, and in particular the role of metal ions, as for example the role of copper in proteins. He and
369:, then Oxford Professor of Chemistry, asked to see Bob.” He was told that three colleges—Christ Church, Pembroke and Wadham—needed a tutor in chemistry. “Each one will invite you to dine. Come back again in two weeks to give me your decision.” Williams joined 515: 44: 1501: 349:. He was impressed by what he saw there, and returned to Sweden after he gained his DPhil in 1950. During the longer stay he worked on protein purification and devised a method called 683: 446: 1471: 481:
between 1952 and 1955, but the birth of their first son, Timothy Ivor, interrupted her final exams. A second son, John M, was born in 1957. In 1981 Jelly published
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Williams argued that spatial separation of the H and OH ions produced in the conversion of ATP to ADP would be necessary for the catalysis. In the same year
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whereby atoms and groups in enzyme active sites are maintained by binding to the apoenzyme in positions and states appropriate to catalyse reactions.
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Williams contributed to understanding of the distribution of the chemical elements in living organisms and in collaborationwith
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Mitchell P (July 1961). "Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism".
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and was a Foreign Member of the Swedish, Portuguese, Czechoslovakian and Belgian science academies. He was a medallist of the
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Pope, M T; Weakley, T J; Williams, R J P (1959). "Distribution of molecular weights in some polyesters and polypeptides".
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manganese through zinc. From these findings he saw a parallel with the selective uptake of metal ions by organisms.
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in celebration of 50 years of its existence Williams described the correspondence between Mitchell and himself.
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Williams, R J P (2011). "Chemical advances in evolution by and changes in use of space during time".
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Williams retired in 1991 and devoted much of his retirement to the writing of the books mentioned.
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Irving, H. M. N. H.; Williams, R. J. P. (1953). "The stability of transition-metal complexes".
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proposed a similar idea in the form of the chemiosmotic hypothesis. In a special issue of the
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Gray, H B; Malmström, B G; Williams, R J P (2000). "Copper coordination in blue proteins".
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Irving, H; Williams, R J P (6 November 1948). "Order of Stability of Metal Complexes".
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in 1944. For his final undergraduate research year he worked with analytical chemist
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in 1955 and remained there for the rest of his life. His doctoral students include
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Mann, Stephen; Thomson, Andrew J. (2015). "Robert J. P. Williams (1926–2015)".
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Proceedings of the National Academy of Sciences of the United States of America
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While he was in Uppsala Williams met Jelly Klara BĂĽchli, a Dutch student from
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is the term used at Merton College for what other colleges call a scholarship.
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The Biological Chemistry of the Elements: the Inorganic Chemistry of Life
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Williams then spent another period back at Merton, having won a junior
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Evolution's Destiny: Co-evolving Chemistry of the Environment and Life
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Williams, R J P (1961). "Possible functions of chains of catalysts".
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Robert Joseph Paton Williams was born on 25 February 1926 in
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The Chemistry of Evolution: The Development of our Ecosystem
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Williams’s plan was to continue working with Irving for his
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he wrote three books in this area, as well as a book with
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Inorganic Chemistry: Principles and non-metals (volume 1)
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to Ernest Ivor Williams, a customs and excise officer at
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An investigation of the complex compounds of some metals
1110:"Metalloenzymes: entatic nature of their active sites" 738:. Wadham College, University of Oxford. Archived from 684:
Biographical Memoirs of Fellows of the Royal Society
212: 200: 182: 172: 151: 134: 111: 101: 91: 72: 50: 23: 276:(25 February 1926 – 21 March 2015) was an English 1405:Hasani, Ilire; Hoffmann, Robert (21 March 2015). 1341:Williams, R J P; FraĂşsto da Silva, J J R (2005). 1316:Williams, R J P; FraĂşsto da Silva, J J R (1996). 1502:Members of the Royal Swedish Academy of Sciences 442:for services to the community in North Oxford. 1318:The Natural Selection of the Chemical Elements 1050:C. S. G. Phillips; R. J. P. Williams (1965). 1025:C. S. G. Phillips; R. J. P. Williams (1965). 509:B. L. Vallee & R. J. P. Williams (1968). 8: 886:History of Modern Biomedicine Research Group 1394:(Supplement). 31 December 2009. p. 23. 318:, having missed six months’ schooling with 1472:Members of the Order of the British Empire 1108:Vallee, B. L.; Williams, R. J. P. (1968). 42: 20: 1143: 1133: 970: 959:Journal of Biological Inorganic Chemistry 778: 767:Journal of Biological Inorganic Chemistry 700: 593: 591: 546: 536: 447:Fellow of the Royal Society (FRS) in 1972 436:Member of the Order of the British Empire 400:In the first paper ever published in the 314:Williams failed to gain a scholarship to 453:(twice), the Royal Society (twice), the 677:Hill, H. A. O.; Thomson, A. J. (2016). 621: 619: 601:Light induced charge transfer in solids 501: 1052:Inorganic Chemistry: Metals (volume 2) 867:. University of Oxford. Archived from 672: 670: 668: 666: 636:(DPhil thesis). University of Oxford. 604:(DPhil thesis). University of Oxford. 7: 1407:"Academy of Europe: Williams Robert" 629:Silicification in biological systems 365:, Then, “out of the blue, in 1954, 1507:Alumni of the University of Oxford 341:, but he first visited the lab of 14: 1482:Fellows of Wadham College, Oxford 291:and an Emeritus Professor at the 655: 423:on geological aspects of life. 393:proposed of the concept of the 124: 410:Journal of Theoretical Biology 402:Journal of Theoretical Biology 1: 955:"The science of RJP Williams" 1477:Fellows of the Royal Society 1374:. Cambridge: RSC Publishing. 1181:10.1016/0022-5193(61)90023-6 865:"R J P Williams (1926–2015)" 718:University of Oxford Gazette 626:Perry, Carole Celia (1985). 265:Robert Joseph Paton Williams 1320:. Oxford: Clarendon Press. 1295:. Oxford: Clarendon Press. 1029:. Oxford University Press. 724:(5093): 499. 23 April 2015. 417:JoĂŁo J. R. FraĂşsto da Silva 16:English chemist (1926–2015) 1523: 1431:Williams, Jelly K (1981). 1291:; Williams, R J P (1991). 1267:10.1016/j.jtbi.2010.09.021 1114:Proc. Natl. Acad. Sci. USA 1054:. Oxford University Press. 953:Thomson, Andrew J (2016). 761:Thomson, Andrew J (2015). 479:St Hilda's College, Oxford 455:Royal Society of Chemistry 972:10.1007/s00775-015-1328-5 780:10.1007/s00775-015-1262-6 488:Bob Williams died in the 258: 144: 41: 299:Education and early life 1289:FraĂşsto da Silva, J J R 490:John Radcliffe Hospital 434:Williams was appointed 316:Wallasey Grammar School 842:10.1002/ange.201504131 702:10.1098/rsbm.2016.0020 371:Wadham College, Oxford 324:Merton College, Oxford 289:Wadham College, Oxford 106:Irving–Williams series 1135:10.1073/pnas.59.2.498 1079:10.1007/s007750000146 538:10.1073/pnas.59.2.498 440:2010 New Year Honours 1345:. Elsevier Science. 1067:J. Biol. Inorg. Chem 1012:10.1039/jr9590003442 582:10.1039/JR9530003192 461:in 1981 and won the 293:University of Oxford 177:University of Oxford 96:University of Oxford 1487:Royal Medal winners 1216:1961Natur.191..144M 1126:1968PNAS...59..498V 924:1948Natur.162..746I 871:on 9 February 2016. 834:2015AngCh.127.7856M 598:Day, Peter (1965). 529:1968PNAS...59..498V 451:Biochemical Society 363:research fellowship 357:Career and research 67:, Cheshire, England 1391:The London Gazette 650:uk.bl.ethos.354861 492:on 21 March 2015. 430:Awards and honours 347:Uppsala University 1411:Academy of Europe 1366:Williams, R J P; 1210:(4784): 144–148. 918:(4123): 746–747. 821:Angewandte Chemie 445:He was elected a 383:Michael Thor Pope 367:Cyril Hinshelwood 332:transition series 262: 261: 230:Michael Thor Pope 213:Doctoral students 146:Scientific career 1514: 1467:English chemists 1451: 1450: 1428: 1422: 1421: 1419: 1417: 1402: 1396: 1395: 1382: 1376: 1375: 1363: 1357: 1356: 1338: 1332: 1331: 1313: 1307: 1306: 1285: 1279: 1278: 1250: 1244: 1243: 1224:10.1038/191144a0 1199: 1193: 1192: 1164: 1158: 1157: 1147: 1137: 1105: 1099: 1098: 1062: 1056: 1055: 1047: 1041: 1040: 1022: 1016: 1015: 999: 993: 992: 974: 950: 944: 943: 932:10.1038/162746a0 907: 901: 895: 889: 879: 873: 872: 860: 854: 853: 815: 809: 808: 782: 758: 752: 751: 749: 747: 732: 726: 725: 713: 707: 706: 704: 674: 661: 660: 659: 653: 623: 614: 613: 595: 586: 585: 567: 561: 560: 550: 540: 506: 459:Bakerian Lecture 421:Rosalind Rickaby 351:gradient elution 275: 245:Rachel E. Klevit 202:Doctoral advisor 196: 128: 126: 79: 61:25 February 1926 60: 58: 46: 36: 21: 1522: 1521: 1517: 1516: 1515: 1513: 1512: 1511: 1457: 1456: 1455: 1454: 1447: 1430: 1429: 1425: 1415: 1413: 1404: 1403: 1399: 1384: 1383: 1379: 1365: 1364: 1360: 1353: 1340: 1339: 1335: 1328: 1315: 1314: 1310: 1303: 1287: 1286: 1282: 1252: 1251: 1247: 1201: 1200: 1196: 1166: 1165: 1161: 1107: 1106: 1102: 1064: 1063: 1059: 1049: 1048: 1044: 1037: 1024: 1023: 1019: 1001: 1000: 996: 952: 951: 947: 909: 908: 904: 896: 892: 882:Robert Williams 880: 876: 862: 861: 857: 817: 816: 812: 760: 759: 755: 745: 743: 734: 733: 729: 715: 714: 710: 676: 675: 664: 654: 625: 624: 617: 597: 596: 589: 569: 568: 564: 508: 507: 503: 498: 471: 432: 359: 301: 267: 254: 194: 168: 130: 127: 1952) 122: 118: 92:Alma mater 87: 81: 77: 68: 62: 56: 54: 37: 28: 26: 17: 12: 11: 5: 1520: 1518: 1510: 1509: 1504: 1499: 1494: 1489: 1484: 1479: 1474: 1469: 1459: 1458: 1453: 1452: 1445: 1437:Nelson Thornes 1433:A Dutch Reader 1423: 1397: 1377: 1368:Rickaby, R E M 1358: 1351: 1333: 1326: 1308: 1301: 1280: 1261:(1): 146–159. 1255:J. Theor. Biol 1245: 1194: 1169:J. Theor. Biol 1159: 1120:(2): 498–505. 1100: 1073:(5): 551–559. 1057: 1042: 1036:978-0198551188 1035: 1017: 994: 945: 902: 898:Postmastership 890: 874: 855: 810: 773:(4): 617–618. 753: 736:"Bob Williams" 727: 716:"Obituaries". 708: 662: 615: 587: 562: 523:(2): 498–505. 500: 499: 497: 494: 483:A Dutch Reader 470: 467: 431: 428: 406:Peter Mitchell 358: 355: 300: 297: 260: 259: 256: 255: 253: 252: 247: 242: 237: 232: 227: 222: 216: 214: 210: 209: 204: 198: 197: 186: 180: 179: 174: 170: 169: 167: 166: 164:Metalloenzymes 161: 155: 153: 149: 148: 142: 141: 136: 132: 131: 120: 116: 115: 113: 109: 108: 103: 102:Known for 99: 98: 93: 89: 88: 82: 80:(aged 89) 74: 70: 69: 63: 52: 48: 47: 39: 38: 27: 24: 15: 13: 10: 9: 6: 4: 3: 2: 1519: 1508: 1505: 1503: 1500: 1498: 1495: 1493: 1490: 1488: 1485: 1483: 1480: 1478: 1475: 1473: 1470: 1468: 1465: 1464: 1462: 1448: 1446:9780859503495 1442: 1438: 1434: 1427: 1424: 1412: 1408: 1401: 1398: 1393: 1392: 1387: 1381: 1378: 1373: 1369: 1362: 1359: 1354: 1352:9780444521552 1348: 1344: 1337: 1334: 1329: 1327:9780198558422 1323: 1319: 1312: 1309: 1304: 1302:0-19-850848-4 1298: 1294: 1290: 1284: 1281: 1276: 1272: 1268: 1264: 1260: 1256: 1249: 1246: 1241: 1237: 1233: 1229: 1225: 1221: 1217: 1213: 1209: 1205: 1198: 1195: 1190: 1186: 1182: 1178: 1174: 1170: 1163: 1160: 1155: 1151: 1146: 1141: 1136: 1131: 1127: 1123: 1119: 1115: 1111: 1104: 1101: 1096: 1092: 1088: 1084: 1080: 1076: 1072: 1068: 1061: 1058: 1053: 1046: 1043: 1038: 1032: 1028: 1021: 1018: 1013: 1009: 1006:: 3442–3446. 1005: 1004:J. Chem. Soc. 998: 995: 990: 986: 982: 978: 973: 968: 964: 960: 956: 949: 946: 941: 937: 933: 929: 925: 921: 917: 913: 906: 903: 899: 894: 891: 887: 883: 878: 875: 870: 866: 863:Anon (2015). 859: 856: 851: 847: 843: 839: 835: 831: 827: 823: 822: 814: 811: 806: 802: 798: 794: 790: 786: 781: 776: 772: 768: 764: 757: 754: 742:on 3 May 2015 741: 737: 731: 728: 723: 719: 712: 709: 703: 698: 694: 693:Royal Society 690: 686: 685: 680: 673: 671: 669: 667: 663: 658: 651: 647: 643: 639: 635: 631: 630: 622: 620: 616: 611: 607: 603: 602: 594: 592: 588: 583: 579: 576:: 3192–3210. 575: 574: 573:J. Chem. Soc. 566: 563: 558: 554: 549: 544: 539: 534: 530: 526: 522: 518: 517: 512: 505: 502: 495: 493: 491: 486: 484: 480: 476: 469:Personal life 468: 466: 464: 460: 456: 452: 448: 443: 441: 438:(MBE) in the 437: 429: 427: 424: 422: 418: 413: 411: 407: 403: 398: 396: 395:entatic state 392: 386: 384: 380: 376: 372: 368: 364: 356: 354: 352: 348: 344: 343:Arne Tiselius 340: 335: 333: 329: 325: 321: 317: 312: 310: 306: 298: 296: 294: 290: 286: 283: 279: 274: 270: 266: 257: 251: 248: 246: 243: 241: 238: 236: 233: 231: 228: 226: 223: 221: 218: 217: 215: 211: 208: 205: 203: 199: 192: 191: 187: 185: 181: 178: 175: 171: 165: 162: 160: 157: 156: 154: 150: 147: 143: 140: 137: 133: 114: 110: 107: 104: 100: 97: 94: 90: 85: 76:21 March 2015 75: 71: 66: 53: 49: 45: 40: 35: 31: 22: 19: 1432: 1426: 1416:10 September 1414:. 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London: 496:References 353:analysis. 320:diphtheria 57:1926-02-25 850:0044-8249 789:0949-8257 642:863542406 610:944386301 475:Groningen 465:in 1995. 375:Peter Day 309:Liverpool 220:Peter Day 159:Chemistry 86:, England 1370:(2012). 1275:20869970 1232:13771349 1189:13785509 1087:11085645 989:18533741 981:26759252 805:39414172 797:25913871 746:23 March 634:ox.ac.uk 305:Wallasey 282:Emeritus 65:Wallasey 1240:1784050 1212:Bibcode 1154:5238980 1122:Bibcode 1095:1815405 940:6943144 920:Bibcode 888:website 884:on the 830:Bibcode 557:5238980 525:Bibcode 278:chemist 129:​ 121:​ 1443:  1349:  1324:  1299:  1273:  1238:  1230:  1204:Nature 1187:  1152:  1145:224700 1142:  1093:  1085:  1033:  987:  979:  938:  912:Nature 848:  803:  795:  787:  648:  640:  608:  555:  548:224700 545:  285:Fellow 195:(1950) 193:  184:Thesis 152:Fields 135:Awards 112:Spouse 84:Oxford 1236:S2CID 1091:S2CID 985:S2CID 936:S2CID 801:S2CID 646:EThOS 339:DPhil 280:, an 271: 123:( 119: 32: 1441:ISBN 1418:2022 1347:ISBN 1322:ISBN 1297:ISBN 1271:PMID 1228:PMID 1185:PMID 1150:PMID 1083:PMID 1031:ISBN 977:PMID 846:ISSN 793:PMID 785:ISSN 748:2015 638:OCLC 606:OCLC 553:PMID 381:and 73:Died 51:Born 1263:doi 1259:268 1220:doi 1208:191 1177:doi 1140:PMC 1130:doi 1075:doi 1008:doi 967:doi 928:doi 916:162 838:doi 826:127 775:doi 722:145 697:doi 578:doi 543:PMC 533:doi 345:at 287:at 273:FRS 269:MBE 34:FRS 30:MBE 1463:: 1439:. 1435:. 1409:. 1388:. 1269:. 1257:. 1234:. 1226:. 1218:. 1206:. 1183:. 1171:. 1148:. 1138:. 1128:. 1118:59 1116:. 1112:. 1089:. 1081:. 1069:. 983:. 975:. 963:21 961:. 957:. 934:. 926:. 914:. 844:. 836:. 824:. 799:. 791:. 783:. 771:20 769:. 765:. 720:. 689:62 687:. 681:. 665:^ 644:. 632:. 618:^ 590:^ 551:. 541:. 531:. 521:59 519:. 513:. 485:. 385:. 377:, 295:. 125:m. 1449:. 1420:. 1355:. 1330:. 1305:. 1277:. 1265:: 1242:. 1222:: 1214:: 1191:. 1179:: 1173:1 1156:. 1132:: 1124:: 1097:. 1077:: 1071:5 1039:. 1014:. 1010:: 991:. 969:: 942:. 930:: 922:: 852:. 840:: 832:: 807:. 777:: 750:. 705:. 699:: 652:. 612:. 584:. 580:: 559:. 535:: 527:: 59:) 55:(

Index

MBE
FRS

Wallasey
Oxford
University of Oxford
Irving–Williams series
Royal Medal
Chemistry
Metalloenzymes
University of Oxford
Thesis
An investigation of the complex compounds of some metals
Doctoral advisor
Harry Irving
Peter Day
Carole Perry
Michael Thor Pope
Tony Orchard
Chris Dobson
Rachel E. Klevit
Stephen Mann
MBE
FRS
chemist
Emeritus
Fellow
Wadham College, Oxford
University of Oxford
Wallasey

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