287:
264:
40:
448:
is a brief peripheral vasodilator; this compound was made to make its action longer and effective. It provokes cutaneous flushing in head and upper thorax with heat, but with no major effects in blood pressure. It is used in peripheral vascular diseases, like
78:
403:
1517:
740:
468:
Fischer and
Tebrock worked with this drug in more than two hundred patients for more than three years, achieving effective improvements, mainly in symptoms related to
60:
364:
557:
1407:
992:
1510:
1461:
695:
Fisher MM, Tebrock HW (1953). "Nicotinic alcohol (roniacol) in peripheral vascular diseases and allied conditions: its use and limitations".
733:
384:
1836:
1503:
771:
726:
121:
1841:
1831:
996:
762:
442:
It appears as a crystal that dissolves in water and alcohol with ease, also soluble in ether; melting range 147–148 °C.
203:
1478:
450:
243:
1422:
469:
1321:
1287:
1202:
944:
565:
55:
Roniacol; Roniacol tartrate; Nicotinyl tartrate; Nicotinyl alcohol tartrate; Nicotinic alcohol; Pyridylcarbinol
632:
587:
Richter IH, Fogel M, Fabricant H (1951). "An evaluation of roniacol tartrate in arteriosclerosis obliterans".
1466:
1346:
1341:
1316:
1283:
1245:
1029:
948:
884:
811:
615:"Medical Dictionary, Dictionary of medicine and human biology, medical, biological and chemical terminology"
614:
282:
1331:
1326:
1113:
1846:
1701:
1336:
803:
1377:
1103:
962:
458:
454:
1729:
1691:
1663:
749:
432:
259:
138:
1539:
1361:
807:
499:
494:
484:
428:
489:
1356:
1025:
880:
704:
677:
596:
539:
232:
350:
1588:
667:
659:
531:
299:
212:
1601:
1241:
1057:
192:
147:
286:
263:
1696:
1472:
1198:
1038:
672:
647:
522:
445:
1825:
1775:
1567:
845:
835:
535:
275:
70:
520:
Norwood WF (1963). "Vasodilator
Effects of Nicotinyl Tartrate (Roniacol Tartrate)".
1745:
1686:
1583:
1530:
1447:
1123:
1118:
1085:
1076:
1048:
977:
928:
918:
898:
893:
753:
101:
96:
91:
86:
31:
172:
1724:
1668:
1547:
1526:
1495:
1427:
1402:
1382:
1351:
1259:
1231:
1226:
1221:
1216:
1211:
1163:
1158:
1148:
1143:
1108:
1015:
1005:
933:
923:
903:
853:
820:
436:
39:
1800:
1795:
1780:
1770:
1765:
1760:
1755:
1630:
1593:
1578:
1442:
1417:
1397:
1392:
1387:
1296:
1269:
1264:
1254:
1168:
1138:
1133:
1128:
1062:
1010:
972:
913:
908:
830:
825:
788:
718:
462:
326:
183:
1805:
1785:
1750:
1635:
1625:
1615:
1610:
1552:
1153:
840:
793:
783:
64:
708:
681:
663:
600:
543:
1790:
1719:
1620:
1557:
1437:
1432:
1412:
1184:
957:
849:
480:
At least a couple of uses for this agent were discovered over the years:
17:
1810:
1279:
1095:
158:
1678:
1653:
967:
876:
775:
1711:
867:
349:
340:
223:
1499:
722:
248:
648:"Nicotinyl Alcohol Tartrate in Intermittent Claudication"
439:. It causes flushing and may decrease blood pressure.
410:
1738:
1710:
1677:
1646:
1566:
1538:
1370:
1309:
1278:
1240:
1197:
1177:
1094:
1084:
1075:
1047:
1024:
991:
942:
875:
866:
802:
770:
761:
338:
325:
298:
293:
274:
242:
222:
202:
182:
157:
137:
112:
77:
59:
51:
46:
171:
146:
392:InChI=1S/C6H7NO/c8-5-6-2-1-3-7-4-6/h1-4,8H,5H2
1511:
734:
8:
465:or migraine associated with vascular spasm.
30:
1518:
1504:
1496:
1091:
1081:
872:
767:
741:
727:
719:
285:
262:
191:
1408:Magnesium pyridoxal 5-phosphate glutamate
671:
633:"Buergers disease by dr .ravinder narwal"
211:
512:
389:
369:
258:
126:
276:
29:
231:
69:
7:
100:
90:
162:
697:New York State Journal of Medicine
589:New York State Journal of Medicine
25:
772:Cholesterol absorption inhibitors
536:10.1001/jama.1963.03710110065012
316:
310:
38:
1540:Phenylethanolamine derivatives
457:, thromboangiitis obliterans (
319:
304:
1:
1739:Other peripheral vasodilators
472:, ulcer healing and others.
451:arteriosclerosis obliterans
1863:
294:Chemical and physical data
1456:
1423:Omega−3-acid ethyl esters
562:Medical Dictionary Online
470:intermittent claudication
400:
380:
360:
117:
37:
1322:Bempedoic acid/ezetimibe
943:Niacin and derivatives (
635:. July 7, 2011. page 18.
1837:Hydroxymethyl compounds
1527:Peripheral vasodilators
1347:Fenofibrate/simvastatin
1342:Fenofibrate/pravastatin
1317:Amlodipine/atorvastatin
652:British Medical Journal
1647:Niacin and derivatives
1332:Ezetimibe/rosuvastatin
1327:Ezetimibe/atorvastatin
804:Bile acid sequestrants
664:10.1136/bmj.1.5012.207
646:Gillhespy, RO (1957).
564:. 2012. Archived from
502:(Topanicate, MG 28362)
461:), arterial embolism,
129:(Pyridin-3-yl)methanol
1702:Etofylline nicotinate
1337:Ezetimibe/simvastatin
750:Lipid-lowering agents
431:derivative used as a
1842:Hypolipidemic agents
1378:Alipogene tiparvovec
1104:Aluminium clofibrate
963:Aluminium nicotinate
1832:3-Pyridyl compounds
1730:Dihydroergocristine
1692:Xantinol nicotinate
1664:Inositol nicotinate
1114:Choline fenofibrate
433:hypolipidemic agent
34:
1679:Purine derivatives
1483:Never to phase III
1362:Niacin/simvastatin
1352:Niacin/laropiprant
1819:
1818:
1659:Nicotinyl alcohol
1493:
1492:
1357:Niacin/lovastatin
1305:
1304:
1193:
1192:
1071:
1070:
1026:ATP citrate lyase
983:Nicotinyl alcohol
881:HMG-CoA reductase
862:
861:
459:Buerger's disease
455:Raynaud's disease
421:Nicotinyl alcohol
418:
417:
351:Interactive image
244:CompTox Dashboard
32:Nicotinyl alcohol
27:Chemical compound
16:(Redirected from
1854:
1589:Phenoxybenzamine
1520:
1513:
1506:
1497:
1242:PCSK9 inhibitors
1092:
1082:
873:
768:
743:
736:
729:
720:
713:
712:
692:
686:
685:
675:
643:
637:
636:
629:
623:
622:
619:www.theodora.com
611:
605:
604:
584:
578:
577:
575:
573:
568:on June 14, 2011
558:"Ronicol Retard"
554:
548:
547:
517:
414:
413:
406:
353:
333:
321:
318:
312:
306:
289:
278:
267:
266:
252:
250:
235:
215:
195:
175:
165:
164:
150:
104:
94:
73:
42:
35:
33:
21:
1862:
1861:
1857:
1856:
1855:
1853:
1852:
1851:
1822:
1821:
1820:
1815:
1734:
1712:Ergot alkaloids
1706:
1673:
1642:
1605:
1562:
1534:
1524:
1494:
1489:
1488:
1473:Clinical trials
1452:
1366:
1301:
1274:
1236:
1199:CETP inhibitors
1189:
1173:
1067:
1058:Dextrothyroxine
1043:
1020:
987:
938:
858:
798:
757:
747:
717:
716:
694:
693:
689:
645:
644:
640:
631:
630:
626:
613:
612:
608:
586:
585:
581:
571:
569:
556:
555:
551:
519:
518:
514:
509:
478:
425:pyridylcarbinol
409:
407:
404:(what is this?)
401:
396:
393:
388:
387:
376:
373:
368:
367:
356:
331:
315:
309:
270:
246:
238:
218:
198:
178:
161:
153:
133:
130:
125:
124:
108:
28:
23:
22:
15:
12:
11:
5:
1860:
1858:
1850:
1849:
1844:
1839:
1834:
1824:
1823:
1817:
1816:
1814:
1813:
1808:
1803:
1798:
1793:
1788:
1783:
1778:
1773:
1768:
1763:
1758:
1753:
1748:
1742:
1740:
1736:
1735:
1733:
1732:
1727:
1722:
1716:
1714:
1708:
1707:
1705:
1704:
1699:
1697:Pentoxifylline
1694:
1689:
1683:
1681:
1675:
1674:
1672:
1671:
1666:
1661:
1656:
1650:
1648:
1644:
1643:
1641:
1640:
1639:
1638:
1633:
1628:
1623:
1618:
1613:
1603:
1598:
1597:
1596:
1591:
1586:
1581:
1575:Non-selective
1572:
1570:
1568:Alpha blockers
1564:
1563:
1561:
1560:
1555:
1550:
1544:
1542:
1536:
1535:
1525:
1523:
1522:
1515:
1508:
1500:
1491:
1490:
1487:
1486:
1485:
1484:
1481:
1470:
1464:
1458:
1457:
1454:
1453:
1451:
1450:
1445:
1440:
1435:
1430:
1425:
1420:
1415:
1410:
1405:
1400:
1395:
1390:
1385:
1380:
1374:
1372:
1368:
1367:
1365:
1364:
1359:
1354:
1349:
1344:
1339:
1334:
1329:
1324:
1319:
1313:
1311:
1307:
1306:
1303:
1302:
1300:
1299:
1293:
1291:
1276:
1275:
1273:
1272:
1267:
1262:
1257:
1251:
1249:
1238:
1237:
1235:
1234:
1229:
1224:
1219:
1214:
1208:
1206:
1195:
1194:
1191:
1190:
1188:
1187:
1181:
1179:
1175:
1174:
1172:
1171:
1166:
1161:
1156:
1151:
1146:
1141:
1136:
1131:
1126:
1121:
1116:
1111:
1106:
1100:
1098:
1089:
1079:
1073:
1072:
1069:
1068:
1066:
1065:
1060:
1054:
1052:
1045:
1044:
1042:
1041:
1039:Bempedoic acid
1035:
1033:
1022:
1021:
1019:
1018:
1013:
1008:
1002:
1000:
989:
988:
986:
985:
980:
975:
970:
965:
960:
954:
952:
940:
939:
937:
936:
931:
926:
921:
916:
911:
906:
901:
896:
890:
888:
870:
864:
863:
860:
859:
857:
856:
843:
838:
833:
828:
823:
817:
815:
800:
799:
797:
796:
791:
786:
780:
778:
765:
759:
758:
748:
746:
745:
738:
731:
723:
715:
714:
687:
658:(2): 207–208.
638:
624:
606:
595:(10): 1303–4.
579:
549:
511:
510:
508:
505:
504:
503:
497:
492:
487:
477:
474:
446:Nicotinic acid
416:
415:
398:
397:
395:
394:
391:
383:
382:
381:
378:
377:
375:
374:
371:
363:
362:
361:
358:
357:
355:
354:
346:
344:
336:
335:
329:
323:
322:
313:
307:
302:
296:
295:
291:
290:
280:
272:
271:
269:
268:
255:
253:
240:
239:
237:
236:
228:
226:
220:
219:
217:
216:
208:
206:
200:
199:
197:
196:
188:
186:
180:
179:
177:
176:
168:
166:
155:
154:
152:
151:
143:
141:
135:
134:
132:
131:
128:
120:
119:
118:
115:
114:
110:
109:
107:
106:
83:
81:
75:
74:
67:
57:
56:
53:
49:
48:
44:
43:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1859:
1848:
1845:
1843:
1840:
1838:
1835:
1833:
1830:
1829:
1827:
1812:
1809:
1807:
1804:
1802:
1799:
1797:
1794:
1792:
1789:
1787:
1784:
1782:
1779:
1777:
1776:Naftidrofuryl
1774:
1772:
1769:
1767:
1764:
1762:
1759:
1757:
1754:
1752:
1749:
1747:
1744:
1743:
1741:
1737:
1731:
1728:
1726:
1723:
1721:
1718:
1717:
1715:
1713:
1709:
1703:
1700:
1698:
1695:
1693:
1690:
1688:
1685:
1684:
1682:
1680:
1676:
1670:
1667:
1665:
1662:
1660:
1657:
1655:
1652:
1651:
1649:
1645:
1637:
1634:
1632:
1629:
1627:
1624:
1622:
1619:
1617:
1614:
1612:
1609:
1608:
1607:
1599:
1595:
1592:
1590:
1587:
1585:
1582:
1580:
1577:
1576:
1574:
1573:
1571:
1569:
1565:
1559:
1556:
1554:
1551:
1549:
1546:
1545:
1543:
1541:
1537:
1532:
1528:
1521:
1516:
1514:
1509:
1507:
1502:
1501:
1498:
1482:
1480:
1477:
1476:
1474:
1471:
1468:
1465:
1463:
1460:
1459:
1455:
1449:
1446:
1444:
1441:
1439:
1436:
1434:
1431:
1429:
1426:
1424:
1421:
1419:
1416:
1414:
1411:
1409:
1406:
1404:
1401:
1399:
1396:
1394:
1391:
1389:
1386:
1384:
1381:
1379:
1376:
1375:
1373:
1369:
1363:
1360:
1358:
1355:
1353:
1350:
1348:
1345:
1343:
1340:
1338:
1335:
1333:
1330:
1328:
1325:
1323:
1320:
1318:
1315:
1314:
1312:
1308:
1298:
1295:
1294:
1292:
1289:
1285:
1281:
1277:
1271:
1268:
1266:
1263:
1261:
1258:
1256:
1253:
1252:
1250:
1247:
1243:
1239:
1233:
1230:
1228:
1225:
1223:
1220:
1218:
1215:
1213:
1210:
1209:
1207:
1204:
1200:
1196:
1186:
1183:
1182:
1180:
1176:
1170:
1167:
1165:
1162:
1160:
1157:
1155:
1152:
1150:
1147:
1145:
1142:
1140:
1137:
1135:
1132:
1130:
1127:
1125:
1122:
1120:
1117:
1115:
1112:
1110:
1107:
1105:
1102:
1101:
1099:
1097:
1093:
1090:
1087:
1086:PPAR agonists
1083:
1080:
1078:
1077:Blood vessels
1074:
1064:
1061:
1059:
1056:
1055:
1053:
1050:
1049:Thyromimetics
1046:
1040:
1037:
1036:
1034:
1031:
1027:
1023:
1017:
1014:
1012:
1009:
1007:
1004:
1003:
1001:
998:
994:
990:
984:
981:
979:
976:
974:
971:
969:
966:
964:
961:
959:
956:
955:
953:
950:
946:
941:
935:
932:
930:
927:
925:
922:
920:
917:
915:
912:
910:
907:
905:
902:
900:
897:
895:
892:
891:
889:
886:
882:
878:
874:
871:
869:
865:
855:
851:
847:
846:Soluble fiber
844:
842:
839:
837:
836:Colestyramine
834:
832:
829:
827:
824:
822:
819:
818:
816:
813:
809:
805:
801:
795:
792:
790:
787:
785:
782:
781:
779:
777:
773:
769:
766:
764:
760:
755:
751:
744:
739:
737:
732:
730:
725:
724:
721:
710:
706:
702:
698:
691:
688:
683:
679:
674:
669:
665:
661:
657:
653:
649:
642:
639:
634:
628:
625:
620:
616:
610:
607:
602:
598:
594:
590:
583:
580:
567:
563:
559:
553:
550:
545:
541:
537:
533:
529:
525:
524:
516:
513:
506:
501:
498:
496:
493:
491:
488:
486:
483:
482:
481:
475:
473:
471:
466:
464:
460:
456:
452:
447:
443:
440:
438:
434:
430:
426:
422:
412:
405:
399:
390:
386:
379:
370:
366:
359:
352:
348:
347:
345:
342:
337:
330:
328:
324:
303:
301:
297:
292:
288:
284:
281:
279:
277:ECHA InfoCard
273:
265:
261:
260:DTXSID6023367
257:
256:
254:
245:
241:
234:
230:
229:
227:
225:
221:
214:
210:
209:
207:
205:
201:
194:
190:
189:
187:
185:
181:
174:
170:
169:
167:
160:
156:
149:
145:
144:
142:
140:
136:
127:
123:
116:
111:
103:
98:
93:
88:
85:
84:
82:
80:
76:
72:
68:
66:
62:
58:
54:
50:
47:Clinical data
45:
41:
36:
19:
1847:Vasodilators
1746:Cyclandelate
1687:Pentifylline
1658:
1584:Phentolamine
1448:Volanesorsen
1310:Combinations
1282:inhibitors (
1124:Clinofibrate
1119:Ciprofibrate
1028:inhibitors (
995:inhibitors (
982:
978:Nicofuranose
929:Rosuvastatin
919:Pitavastatin
899:Cerivastatin
894:Atorvastatin
700:
696:
690:
655:
651:
641:
627:
618:
609:
592:
588:
582:
570:. Retrieved
566:the original
561:
552:
527:
521:
515:
479:
467:
444:
441:
424:
420:
419:
408:
402:
1725:Nicergoline
1669:Ciclonicate
1548:Isoxsuprine
1469:from market
1428:Policosanol
1403:Lapaquistat
1383:Azacosterol
1260:Bococizumab
1232:Torcetrapib
1227:Obicetrapib
1222:Evacetrapib
1217:Dalcetrapib
1212:Anacetrapib
1164:Ronifibrate
1159:Pemafibrate
1149:Gemfibrozil
1144:Fenofibrate
1109:Bezafibrate
1016:Mitratapide
1006:Dirlotapide
934:Simvastatin
924:Pravastatin
904:Fluvastatin
854:glucomannan
821:Colesevelam
703:(1): 65–8.
500:Pantenicate
495:Nicofibrate
485:Eniclobrate
476:Derivatives
437:vasodilator
334: g·mol
283:100.002.604
233:CHEBI:45213
113:Identifiers
52:Other names
1826:Categories
1801:Ifenprodil
1796:Cinepazide
1781:Butalamine
1771:Sulcotidil
1766:Vinburnine
1761:Bencyclane
1756:Moxisylyte
1631:Tamsulosin
1600:Selective
1594:Tolazoline
1579:Buflomedil
1443:Triparanol
1418:Mipomersen
1398:Darapladib
1393:Benfluorex
1388:Azalanstat
1297:Evinacumab
1270:Inclisiran
1265:Evolocumab
1255:Alirocumab
1169:Simfibrate
1139:Etofibrate
1134:Clofibride
1129:Clofibrate
1063:Resmetirom
1011:Lomitapide
973:Niceritrol
914:Mevastatin
909:Lovastatin
831:Colestipol
826:Colestilan
789:Hyzetimibe
507:References
463:chilblains
372:OCc1cccnc1
339:3D model (
327:Molar mass
213:9TF312056Y
184:ChemSpider
139:CAS Number
122:IUPAC name
1806:Azapetine
1786:Visnadine
1751:Vincamine
1636:Terazosin
1626:Silodosin
1616:Doxazosin
1611:Alfuzosin
1606:-blockers
1553:Buphenine
1479:Phase III
1467:Withdrawn
1154:Nafenopin
841:Colextran
794:SCH-48461
784:Ezetimibe
490:Mepiroxol
435:and as a
71:Monograph
65:Drugs.com
1791:Cetiedil
1720:Ergoloid
1621:Prazosin
1558:Bamethan
1438:Tiadenol
1433:Probucol
1413:Meglutol
1185:GW501516
1096:Fibrates
958:Acipimox
850:psyllium
848:such as
763:GI tract
709:13025721
682:13383231
601:14843421
572:July 27,
544:14066712
530:: 1013.
411:(verify)
148:100-55-0
79:ATC code
18:Roniacol
1811:Fasudil
1280:ANGPTL3
877:Statins
673:1974214
427:) is a
332:109.128
300:Formula
159:PubChem
99: (
97:C04AC02
95:)
89: (
87:C10AD05
1654:Niacin
1602:α
1462:WHO-EM
1178:Others
1051:(VLDL)
968:Niacin
808:resins
776:NPC1L1
707:
680:
670:
599:
542:
429:niacin
365:SMILES
1371:Other
1088:(LDL)
868:Liver
385:InChI
341:JSmol
224:ChEBI
997:VLDL
993:MTTP
947:and
852:and
705:PMID
678:PMID
597:PMID
574:2012
540:PMID
523:JAMA
204:UNII
193:7229
173:7510
61:AHFS
1531:C04
1288:HDL
1284:LDL
1246:LDL
1203:HDL
1030:LDL
949:LDL
945:HDL
885:LDL
812:LDL
754:C10
668:PMC
660:doi
532:doi
528:186
249:EPA
163:CID
102:WHO
92:WHO
1828::
1475::
883:,
774:,
701:53
699:.
676:.
666:.
656:18
654:.
650:.
617:.
593:51
591:.
560:.
538:.
526:.
453:,
1604:1
1533:)
1529:(
1519:e
1512:t
1505:v
1290:)
1286:/
1248:)
1244:(
1205:)
1201:(
1032:)
999:)
951:)
887:)
879:(
814:)
810:(
806:/
756:)
752:(
742:e
735:t
728:v
711:.
684:.
662::
621:.
603:.
576:.
546:.
534::
423:(
343:)
320:O
317:N
314:7
311:H
308:6
305:C
251:)
247:(
105:)
63:/
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
