954:
Zheng, Huisong; Xie, Yinlong; Tap, Julien; Lepage, Patricia; Bertalan, Marcelo; Batto, Jean-Michel; Hansen, Torben; Le
Paslier, Denis; Linneberg, Allan; Nielsen, H. Bjørn; Pelletier, Eric; Renault, Pierre; Sicheritz-Ponten, Thomas; Turner, Keith; Zhu, Hongmei; Yu, Chang; Li, Shengting; Jian, Min; Zhou, Yan; Li, Yingrui; Zhang, Xiuqing; Li, Songgang; Qin, Nan; Yang, Huanming; Wang, Jian; Brunak, Søren; Doré, Joel; Guarner, Francisco; Kristiansen, Karsten; Pedersen, Oluf; Parkhill, Julian; Weissenbach, Jean; Antolin, Maria; Artiguenave, François; Blottiere, Hervé; Borruel, Natalia; Bruls, Thomas; Casellas, Francesc; Chervaux, Christian; Cultrone, Antonella; Delorme, Christine; Denariaz, Gérard; Dervyn, Rozenn; Forte, Miguel; Friss, Carsten; van de Guchte, Maarten; Guedon, Eric; Haimet, Florence; Jamet, Alexandre; Juste, Catherine; Kaci, Ghalia; Kleerebezem, Michiel; Knol, Jan; Kristensen, Michel; Layec, Severine; Le Roux, Karine; Leclerc, Marion; Maguin, Emmanuelle; Melo Minardi, Raquel; Oozeer, Raish; Rescigno, Maria; Sanchez, Nicolas; Tims, Sebastian; Torrejon, Toni; Varela, Encarna; de Vos, Willem; Winogradsky, Yohanan; Zoetendal, Erwin; Bork, Peer; Ehrlich, S. Dusko; Wang, Jun (2010).
339:. In particular, machine learning-based prediction and the general area of integrative systems biology where heterogeneous data from the molecular level are combined with phenotypic data from the healthcare sector. A general aim is to understand disease mechanisms at the level of protein network biology. An additional focus area is human proteome variation and precision medicine, where patient-specific adverse drug reaction profiles and the discrimination between treatment-related disease correlations and other comorbidities are investigated. The group engages in non-hypothesis-driven research, where massive amounts of data from widely different experimental technologies are combined and analysed with the objective of making discoveries that emerge from the data rather than being the result of specific experiments designed to confirm or disprove given hypotheses. The Brunak group has also over the years been highly within
214:. He is a professor of Disease Systems Biology at the University of Copenhagen and professor of bioinformatics at the Technical University of Denmark. As Research Director at the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen Medical School, he leads a research effort where molecular-level systems biology data are combined with phenotypic data from the healthcare sector, such as electronic patient records, registry information, and biobank questionnaires. A major aim is to understand the network biology basis for time-ordered comorbidities and discriminate between treatment-related disease correlations and other comorbidities in disease trajectories. Søren Brunak also holds a position as a Medical Informatics Officer at Rigshospitalet, the Capital Region of Denmark.
31:
840:
569:
953:
Qin, Junjie; Li, Ruiqiang; Raes, Jeroen; Arumugam, Manimozhiyan; Burgdorf, Kristoffer
Solvsten; Manichanh, Chaysavanh; Nielsen, Trine; Pons, Nicolas; Levenez, Florence; Yamada, Takuji; Mende, Daniel R.; Li, Junhua; Xu, Junming; Li, Shaochuan; Li, Dongfang; Cao, Jianjun; Wang, Bo; Liang, Huiqing;
414:(ISCB) 2001–2004, of the Danish Academy of Technical Sciences since 2002, the Danish Royal Society of Sciences and Letters since 2004, and of the Royal Swedish Academy of Sciences from 2016. He is a fellow of the International Society for Computational Biology (2009), and a Member of the
426:
in 2011. He was awarded the Julius
Thomsen's gold medal in 2013 and Dir. Ib Henriksens Prize for Outstanding Science Achievement in 2002. He was awarded the Villum Kann Rasmussen Prize for Research within the Natural and Technical Sciences (2006).
1948:
1215:
1958:
1973:
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and has produced numerous, highly used prediction methods, including SignalP, TargetP, NetGene, NetPhos, NetOglyc, NetNES, distanceP, and many others. As of 2017, according to
910:
Emanuelsson, Olof; Nielsen, Henrik; Brunak, Søren; von Heijne, Gunnar (2000). "Predicting
Subcellular Localization of Proteins Based on their N-terminal Amino Acid Sequence".
281:
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538:
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at the
Faculty for Health and Medical Sciences of the University of Copenhagen, a leading center for the study of human proteins of therapeutic value.
36:
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478:
Fogg, Christiana N.; Kovats, Diane K. (2016). "Message from the ISCB: 2016 ISCB Accomplishment by a Senior
Scientist Award Given to Søren Brunak".
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276:. A major, early center in bioinformatics that has existed for more than 20 years. In 2007, Søren Brunak was, with
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He has been participating in scientific advisory committees of several scientific organizations, such as the
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698:"Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites"
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Søren Brunak was in 1993 the founding director of the Center for
Biological Sequence Analysis at the
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Development of computational tools for data integration across molecular and phenotypic levels
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Petersen, Thomas
Nordahl; Brunak, Søren; von Heijne, Gunnar; Nielsen, Henrik (2011).
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from the
International Society for Computational Biology in 2016 and elected an
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89:
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773:
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987:
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814:
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956:"A human gut microbial gene catalogue established by metagenomic sequencing"
1057:
1005:
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923:
781:
509:
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888:
832:
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348:
156:
1024:"SignalP 4.0: discriminating signal peptides from transmembrane regions"
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1023:
292:
227:
797:"Neural network detects errors in the assignment of mRNA splice sites"
879:
854:
677:
150:
542:
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239:
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Nielsen, H.; Engelbrecht, J.; Brunak, S.; Von Heijne, G. (1997).
246:
in 1991 at the
Department of Structural Properties of Materials,
1180:
748:(2004). "Improved Prediction of Signal Peptides: SignalP 3.0".
1949:
Fellows of the International Society for Computational Biology
1124:
Lund O, Nielsen M, Lundegaard C, Kesmir C, Brunak S (2005).
303:(chairman), the Bioinformatics Advisory Committee at the
406:
Brunak has been a member of the Danish Academy for the
319:(Stockholm) and the Swiss Institute of Bioinformatics.
1959:
Members of the European Molecular Biology Organization
609:(MSc thesis). København : Niels Bohr Institutet.
410:
since 1997, a member of the Board of directors of the
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Novo Nordisk Foundation Center for Protein Research
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52:
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853:Brunak, S.; Engelbrecht, J.; Knudsen, S. (1990).
795:Brunak, S.; Engelbrecht, J.; Knudsen, S. (1990).
691:
689:
1974:Members of the Royal Swedish Academy of Sciences
1212:International Society for Computational Biology
556:
554:
552:
539:International Society for Computational Biology
412:International Society for Computational Biology
1192:
1111:Bioinformatics: The Machine Learning Approach
391:Bioinformatics: The Machine Learning Approach
202:biological and physical scientist working in
8:
735:
733:
313:Max Planck Institute for Molecular Genetics
1199:
1185:
1177:
1085:Neural Networks - Computers with Intuition
567:
386:Neural Networks - Computers with Intuition
29:
18:
16:Danish bioinformatics professor, scientist
1168:"Previous recipients of the annual award"
1039:
995:
878:
822:
763:
713:
524:
522:
37:Intelligent Systems for Molecular Biology
702:Protein Engineering Design and Selection
473:
471:
354:publications have been published in the
456:European Molecular Biology Organization
441:
439:
435:
416:European Molecular Biology Organization
280:, a founding research director of the
1099:(also published in Danish and German)
289:European Molecular Biology Laboratory
7:
740:Dyrløv Bendtsen, J.; Nielsen, H.;
14:
305:European Bioinformatics Institute
297:European Bioinformatics Institute
838:
1087:. World Scientific Publishing.
301:Wellcome Trust Sanger Institute
274:Technical University of Denmark
248:Technical University of Denmark
144:Technical University of Denmark
69:Technical University of Denmark
1140:"Commemoration Day 2013 - DTU"
1:
494:10.1093/bioinformatics/btw291
418:in 2009. Brunak received the
327:Brunak's main research is in
35:Søren Brunak speaking at the
1126:Immunological Bioinformatics
912:Journal of Molecular Biology
855:"Cleaning up gene databases"
751:Journal of Molecular Biology
629:"Staff - DTU Bioinformatics"
396:Immunological Bioinformatics
357:Journal of Molecular Biology
674:Søren Brunak's publications
420:ISCB Senior Scientist Award
317:Science for Life Laboratory
96:ISCB Senior Scientist Award
48:1958 (age 65–66)
1990:
1113:(2nd ed.). MIT Press.
1109:Baldi P, Brunak S (2001).
380:Selected book publications
250:, and in 2002 a Dr.Phil. (
222:Søren Brunak obtained his
774:10.1016/j.jmb.2004.05.028
167:
111:
28:
1954:Danish bioinformaticians
680:bibliographic database.
563:publications indexed by
236:University of Copenhagen
187:/disease-systems-biology
141:University of Copenhagen
65:University of Copenhagen
1011:(subscription required)
682:(subscription required)
515:(subscription required)
924:10.1006/jmbi.2000.3903
815:10.1093/nar/18.16.4797
802:Nucleic Acids Research
715:10.1093/protein/10.1.1
605:Brunak, Søren (1987).
244:Computational Biology
291:(EMBL, Heidelberg),
262:Stockholm University
232:Niels Bohr Institute
1857:Gustavo Stolovitzky
1481:Julio Collado-Vides
980:10.1038/nature08821
972:2010Natur.464...59.
871:1990Natur.343..123B
362:Protein Engineering
337:medical informatics
230:, in 1987 from the
212:medical informatics
131:Medical Informatics
1964:Systems biologists
1923:Reinhard Schneider
1715:Marie-France Sagot
1710:Xiaole Shirley Liu
1041:10.1038/nmeth.1701
39:conference in 2016
1931:
1930:
1837:Núria López Bigas
1771:Katherine Pollard
1731:Serafim Batzoglou
1654:Terry Gaasterland
1378:Gunnar von Heijne
1317:Michael Ashburner
1094:978-9971-5-0939-2
809:(16): 4797–4801.
607:Computerens fysik
488:(11): 1758–1759.
402:Awards and honors
224:Master of Science
198:(born 1958) is a
193:
192:
157:Computerens fysik
113:Scientific career
1981:
1888:Takashi Gojobori
1847:Teresa Przytycka
1827:Christina Leslie
1649:Patricia Babbitt
1628:Olga Troyanskaya
1552:Christine Orengo
1450:Robert Gentleman
1301:Alfonso Valencia
1260:Michael Waterman
1216:year of election
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918:(4): 1005–1016.
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880:10.1038/343123a0
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792:
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659:. Archived from
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541:. Archived from
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408:Natural Sciences
341:machine learning
309:Institut Pasteur
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33:
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1883:Mikhail Gelfand
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1807:A. Keith Dunker
1790:
1761:Rafael Irizarry
1741:Mark Borodovsky
1719:
1688:
1674:William Pearson
1637:
1603:Andrea Califano
1586:
1572:Anna Tramontano
1567:Sarah Teichmann
1522:Helen M. Berman
1510:
1496:Thomas Lengauer
1459:
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1419:Steven Salzberg
1404:Minoru Kanehisa
1399:David Eisenberg
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1281:Lawrence Hunter
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1034:(10): 785–786.
1021:
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1016:
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966:(7285): 59–65.
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765:10.1.1.165.2784
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695:
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687:
681:
676:indexed by the
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651:
650:
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637:
635:
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582:"Brunak, Søren"
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452:people.embo.org
445:
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382:
333:systems biology
325:
270:
260:Faculty of the
258:Natural Science
220:
208:systems biology
175:
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129:
127:Systems Biology
125:
107:
67:
61:Alma mater
40:
24:
17:
12:
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5:
1987:
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1873:Barbara Bryant
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1817:Wolfgang Huber
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1659:Hanah Margalit
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1577:Shoshana Wodak
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1527:Steven Brenner
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1501:Michael Levitt
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1332:Richard Durbin
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1255:Janet Thornton
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1230:David Haussler
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1028:Nature Methods
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945:
902:
845:
787:
758:(4): 783–795.
742:Von Heijne, G.
729:
685:
666:
663:on 2007-11-21.
653:"Soren Brunak"
644:
620:
597:
573:
565:Google Scholar
548:
545:on 2017-03-20.
531:"ISCB Fellows"
518:
481:Bioinformatics
467:
448:"Soren Brunak"
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403:
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373:Nature Methods
345:Google Scholar
329:bioinformatics
324:
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315:(Berlin), the
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1903:Fran Lewitter
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1822:Sorin Istrail
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1812:Eran Halperin
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1705:Eleazar Eskin
1703:
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1618:William Noble
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1608:Daphne Koller
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1562:Lincoln Stein
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1547:Michal Linial
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1746:Rita Casadio
1736:Judith Blake
1700:Vineet Bafna
1633:Tandy Warnow
1623:Lior Pachter
1613:Anders Krogh
1598:Alex Bateman
1582:Haim Wolfson
1532:Dan Gusfield
1445:Nir Friedman
1435:Amos Bairoch
1394:Pierre Baldi
1358:Jill Mesirov
1327:Søren Brunak
1326:
1291:Chris Sander
1286:Eugene Myers
1250:Temple Smith
1235:David Lipman
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1893:Trey Ideker
1776:Ben Raphael
1756:Osamu Gotoh
1751:Paul Flicek
1664:Yves Moreau
1542:Janet Kelso
1537:Barry Honig
1491:Des Higgins
1455:Andrej Šali
1440:Ewan Birney
1322:Phil Bourne
1296:Gary Stormo
1276:Russ Altman
1240:Webb Miller
657:www.mva.org
424:ISCB Fellow
347:, his most
256:) from the
102:ISCB Fellow
90:EMBO Member
53:Nationality
1938:Categories
1842:Dana Pe'er
1802:Atul Butte
1684:Mike Steel
1679:Mona Singh
1557:Aviv Regev
1368:Ron Shamir
1353:Peter Karp
1079:Brunak S,
746:Brunak, S.
638:2017-03-28
633:Cbs.dtu.dk
591:2017-03-28
461:2017-03-28
431:References
226:degree in
1918:Mihai Pop
1878:Sean Eddy
1081:Lautrup B
1050:1548-7091
988:0028-0836
932:0022-2836
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218:Education
185:/research
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323:Research
238:and his
1908:Jun Liu
1832:Ming Li
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1062:S2CID
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240:Ph.D.
1866:2022
1795:2021
1724:2020
1693:2019
1642:2018
1591:2017
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1428:2014
1387:2013
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1089:ISBN
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