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global. Bilateral and single-lung transplants continued to account for most procedures performed. Heart-lung transplants became reserved primarily for those patients with the
Eisenmenger anomaly or severe primary pulmonary hypertension. Jamieson was responsible for numerous descriptions of early heart-lung and double lung transplant techniques.
375:
Before 1980, just under 40 lung transplantation procedures had been attempted, all of which resulted in the patient's death within a few months and just one resulted in the patient's discharge from hospital. In 1979 at
Stanford, Jamieson performed 25 heart transplants, comprising more than 50 percent
448:
Simultaneous work in
Toronto, under Joel D. Cooper and the Toronto transplant group also reported success with single-lung transplants and then with en bloc bilateral lung transplants. Over the next two decades, the state of lung transplantation grew and multiple lung transplant centers became
900:
391:
reports on how cyclosporine led to a reduction in acute rejection and consequent longer survival rates following liver and kidney transplantation, Jamieson then demonstrated the possibility of using cyclosporine in human heart-lung transplantations. Subsequently, with
537:
By 1989, he had performed around 500 heart transplants and more than 50 heart-lung transplants. However, due to the shortage of donor supplies, an attempt was made to reduce heart-lung transplants. The heart was increasingly repaired where possible and
571:
disqualified a patient as fit for surgery. He argued that whatever the degree of right ventricular failure, PTA improved patients lives. While medical management may provide some temporary relief of symptoms, PTE is considered curative for CTEPH.
582:
Jamieson pioneered the procedure of pulmonary thromboendarterectomy (PTE). During his four decades at UCSD, he made modifications to the procedure of PTE, adapted surgical instruments and proposed a classification of CTEPH.
317:, also performed a combined heart-lung transplant in a 49-year-old man with emphysema, surviving for 23 days. The poor survival rates of these early transplantations, primarily resulted from inadequate
2014:
507:, to the University of California, San Diego. to which he introduced heart-lung, lung, double lung and living-related transplant, and established the first lung transplantation programme to be
366:, who had performed the first human heart transplant in America in 1967. Jamieson completed his residency in 1980 and stayed on as chief resident at Shumway's request. Later, he was listed in
575:
By 2011 there were approximately 30 centers worldwide that offered pulmonary endarterectomy and half of the 4,000 procedures performed were being done by
Jamieson's programme directorship at
2039:
479:
as director of the
Minnesota Heart and Lung Institute, performing Minnesota's first heart-lung transplant in the same year. In 1988, he performed the Midwest's first double-lung transplant.
564:(CTEPH). Many physicians have been unaware of the existence of CTEPH and as a consequence it has been underdiagnosed. Jamieson was the first to report that CTEPH can be corrected with PTE.
640:
234:
147:
417:
On 9 March 1981, Jamieson was part of the team that achieved the first long-term survival following a combined heart-lung transplant procedure, led by Bruce Reitz and accompanied by
402:(BMJ) on "Cardiac transplantation in 150 patients at Stanford University". This report was one of the developments that supported the recommencement of heart surgery in the UK under
2024:
2049:
230:. Following that, he continued to make significant contributions to heart-lung transplant procedures, and led programmes in cardiothoracic surgery in both adults and children.
1937:
409:
In
December 1980, he participated in the first successful human heart transplant using cyclosporine. The recipient was then age 20 and still living in 2017 at the age of 58.
1909:
337:
to weaken the bronchial anastomosis. It was on this background of tragic deaths that
Jamieson later acknowledged and shared his research on xenograft hyperacute rejection.
1708:"Pulmonary Endarterectomy Surgery- A Technically Demanding Cure for WHO Group IV Pulmonary Hypertension: Requirements for Centers of Excellence and Availability in Canada"
974:
561:
543:
194:
88:
2009:
301:. Despite surviving less than a day, her case showed that this kind of procedure could be effective. The second such transplant was performed in 1969, by
517:
The
International Registry for Heart Transplantation, which possesses global heart and heart-lung transplants records, and the editorial offices of the
277:. His childhood was spent on a 2.5 million acre ranch with pets that included a zebra, an ostrich and a giraffe. At the age of 18, Jamieson was sent to
2044:
1883:
866:
166:
567:
Jamieson's 2003 publication, describing the first 1,500 cases of PTE, confirmed the benefits of surgery and dismissed the myth that poor right
351:
media coverage of failed early heart transplantations, Jamieson published his first papers on xenograft hyperacute rejection in 1974 and 1975.
1219:
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982:
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906:
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The
Transplantation and Replacement of Thoracic Organs: The Present Status of Biological and Mechanical Replacement of the Heart and Lungs
58:
576:
242:
1440:
1015:
Margreiter, R. (October 2016). "History of Lung and Heart-Lung
Transplantation, With Special Emphasis on German-Speaking Countries".
306:
2004:
1893:
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796:
452:
He co-founded the International Society for Heart and Lung Transplantation (ISHLT) in 1981 and later became its president in 1986.
1435:. Spiro, Stephen G., Silvestri, Gerard A., AgustĂ, Alvar. (4th ed.). Philadelphia, PA: Elsevier Saunders. pp. 882–903.
2034:
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175:
92:
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246:
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In 1982, Jamieson became the director of heart and lung transplantation at Stanford and retained this position until 1986.
278:
652:
Jamieson has published more than 500 scientific papers and authored two key medical textbooks on heart and lung surgery.
1763:
Banks, Dalia A.; Manecke, Gerard R.; Maus, Timothy M.; Kerr, Kim M.; Jamieson, Stuart W. (2011). Joel A. Kaplan (ed.).
634:
141:
628:
355:
223:
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The Sulpizio Family Cardiovascular Center houses the Departments of Cardiology and Emergency Medicine in La Jolla
422:
946:
704:
728:
508:
393:
281:, affiliated with the University of London, to study medicine. He financed his studies by working as a waiter.
709:
476:
418:
398:
238:
760:“Pulmonary endarterectomy: recent changes in a single institution's experience of more than 2,700 patients”
257:
2019:
426:
298:
241:. Later, he became dean of cardiovascular affairs and chair and distinguished professor of surgery at the
171:
69:
850:
691:
739:
716:
1999:
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604:
434:
204:
1547:
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McShane, Pamela J.; Ruiz, Luis G.; Garrity, Edward R. (2012). "75. Clinical Respiratory Medicine".
442:
384:
359:
227:
1495:"ISHLT: The International Society for Heart & Lung Transplantation - Other Achievement Awards"
750:"Technical advances of pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension"
684:"Modern Management of Chronic Pulmonary Thromboembolism including Pulmonary Thromboendarterectomy"
495:
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425:, lived for 5 years. A series of combined heart-lung transplant procedures followed in which
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using cyclosporine, a fungal derivative whose immunosuppressive properties were reported by
208:
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363:
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1646:"Pulmonary thromboendarterectomy almost fifty years after the first surgical attempts"
1993:
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773:
615:
Jamieson is a cattle rancher and commercial helicopter pilot. He has three children.
600:
290:
830:
463:
207:
and in December 1980 was part of the team that performed the first successful human
368:
215:
30:
1563:
1465:
1312:
1220:"Norman E. Shumway, 83, Who Made the Heart Transplant a Standard Operation, Dies"
591:
In 1994, Jamieson led the team that performed the first open heart surgery on an
1129:
624:
322:
219:
135:
1723:
1078:
1061:
759:
749:
1983:
1977:
1971:
1965:
975:"UCSD transplant surgeon Stuart Jamieson to receive prestigious pioneer award"
550:
179:
1809:
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1379:
The Search for Anti-Inflammatory Drugs: Case Histories from Concept to Clinic
1280:
1231:
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and Norman Shumway, he published Stanford's achievements in a report in the
310:
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1298:
1272:
1155:
1095:
1044:
713:, No. 1 (1979), pp. 93–95. (With Edward B. Stinson and Norman Shumway)
237:(ISHLT), whilst he was professor and head of cardiothoracic surgery at the
1204:
529:
119:"Pulmonary endarterectomy: Experience and lessons learned in 1,500 cases"
729:"Pulmonary endarterectomy: Experience and lessons learned in 1,500 cases"
557:
380:
326:
270:
266:
186:
47:
1984:
12th Congress Hellenic Society of Thoracic & Cardiovascular Surgeons
1375:"Chapter 2 The History of the Discovery and Development of Cyclosporine"
294:
1769:. David L. Reich, Steven N. Konstadt. Elsevier Saunders. p. 755.
1334:
A History of Organ Transplantation: Ancient Legends to Modern Practice
1317:. University of Puerto Rico Medical Sciences Campus. 1987. p. 55.
503:
By 1989, Jamieson had transferred his entire surgical team, including
553:
256:
182:
1255:
Willis Hurst, J.; Bruce Fye, W.; Robbins, Robert C. (June 2000).
379:
In 1979, he described a series of successful transplantations in
112:"Cardiac transplantation in 150 patients at Stanford University"
705:"Cardiac transplantation in 150 patients at Stanford University"
947:"Recapitulation of the Opening Plenary Session: San Diego 2017"
661:
969:
967:
965:
963:
797:"Organ transplants have come far, but there's more to be done"
607:
when she was two years old. She recovered and made headlines.
1978:
Stuart Jamieson Professor of Surgery | Cardiothoracic Surgery
756:, Vol. 18, Issue 3 (2006), pp. 243–249. (With M. Madani)
289:
The first combined heart-lung transplant was accomplished by
421:
and Norman Shumway. The recipient, a 45-year-old woman with
1855:"11 Pulmonary Hypertension and Antiphospholipid Antibodies"
372:(2000), as one of Norman Shumway's distinguished trainees.
1766:
Kaplan's Cardiac Anesthesia E-Book: Expert Consult Premium
1362:. Reed Business Information. 18 January 1979. p. 155.
222:
team that performed the world's first successful combined
178:(PTE), a surgical procedure performed to remove organized
1336:. Pittsburgh: University of Pittsburgh Pre. p. 509.
1794:. Oudiz, Ronald J. Philadelphia: Elsevier. p. 439.
1706:
Ryan, John J.; Rich, Stuart; Archer, Stephen L. (2011).
1062:"C. Walton Lillehei, the "Father of Open Heart Surgery""
663:
Close to the Sun; The Journey of a Pioneer Heart Surgeon
235:
International Society for Heart and Lung Transplantation
1885:
Karen's Heart: The True Story of a Brave Baby Orangutan
429:
provided blood to the main airways, reducing bronchial
467:
University of Minnesota East Bank campus in the winter
1823:
1821:
1819:
1381:. Springer Science & Business Media. p. 58.
736:, Vol. 76, No. 5 (November 2003), pp. 1457–1464.
1112:
Yeung, Jonathan C.; Keshavjee, Shaf (January 2014).
2015:
Fellows of the Royal College of Surgeons of England
1644:Cerveri, I; D’Armini, A M; Viganò, M (April 2003).
1522:
Exploring America's Highways: Minnesota Trip Trivia
940:
938:
936:
265:Stuart Jamieson was born in 1947 and brought up in
129:
106:
83:
75:
65:
54:
40:
21:
1938:"Irvine H. Page Young Investigator Research Award"
934:
932:
930:
928:
926:
924:
922:
920:
918:
916:
313:. He lived for eight days. In 1971, South African
307:Cornell University Medical Center in New York City
2040:British expatriate academics in the United States
1489:
1487:
1377:. In Merluzzi, Vincent J.; Adams, Julian (eds.).
1853:Piette, Jean-Charles; Hunt, Beverley J. (2006).
1470:. Dimitry Novitzky. Kluwer Academic Publishers.
1403:"World's first successful heart-lung transplant"
1373:Borel, J. F.; Kis, Z. L.; Beveridge, T. (2012).
1010:
1008:
1006:
1004:
1002:
1000:
791:
789:
725:, Vol. 89, No. 3 (March 1986), pp. 383–388.
754:Seminars in Thoracic and Cardiovascular Surgery
445:. Use of cyclosporine reduced acute rejection.
1972:Stuart Jamieson interviews Sir Terence English
1426:
1424:
1250:
1248:
717:"Primary Pulmonary Hypertension and Pregnancy"
376:of the total performed globally at that time.
1552:The Journal of Heart and Lung Transplantation
1171:"Xenograft hyperacute rejection. A new model"
894:
892:
890:
888:
886:
884:
851:"Leading Heart Surgeon to Join Staff at UCSD"
844:
842:
840:
820:
818:
562:chronic thromboembolic pulmonary hypertension
560:) from the pulmonary arteries of people with
544:Chronic thromboembolic pulmonary hypertension
195:chronic thromboembolic pulmonary hypertension
89:chronic thromboembolic pulmonary hypertension
8:
905:. CurtCo/SDM LLC. p. 80. Archived from
261:Stuart Jamieson 2023 (his giraffe on screen)
2050:University of California, San Diego faculty
1910:"Open-Heart Surgery Performed On Orangutan"
1701:
1699:
1697:
1525:. Exploring America's Highway. p. 42.
1118:Cold Spring Harbor Perspectives in Medicine
1114:"Overview of Clinical Lung Transplantation"
1107:
1105:
549:PTE is an operation that removes organized
1859:Hughes Syndrome: Antiphospholipid Syndrome
29:
18:
1739:
1677:
1594:"Stuart W Jamieson | RadcliffeCardiology"
1288:
1186:
1145:
1077:
233:In 1986, he was elected president of the
2025:Physicians of St Mary's Hospital, London
528:
494:
491:UC San Diego Medical Center in Hillcrest
486:
462:
1861:(2nd ed.). Springer. p. 120.
785:
627:Atherosclerosis Research Prize of the
358:awarded him a fellowship to study at
297:, in a two-year-old girl with severe
7:
746:, Vol 1, No. 1 (2004), pp. 1–3.
688:Advanced Therapy in Thoracic Surgery
1314:Puerto Rico Health Sciences Journal
577:University of California, San Diego
521:also moved to UCSD Medical Center.
362:under the pioneering heart surgeon
243:University of California, San Diego
138:Atherosclerosis Research Prize 1978
35:Stuart Jamieson in his library 2019
2010:Alumni of the University of London
1712:The Canadian Journal of Cardiology
1218:Altman, Lawrence K. (2006-02-11).
1029:10.1016/j.transproceed.2016.07.015
14:
1829:"Stuart Jamieson | UCSD Profiles"
200:In his early career, he wrote on
59:St Mary's Hospital Medical School
1857:. In Munther A Khamashta (ed.).
1188:10.1097/00007890-197405000-00016
869:from the original on 6 June 2023
774:10.1016/j.athoracsur.2012.04.004
768:, Vol. 94, Issue 1 (July 2012),
519:Journal of Heart Transplantation
211:using the then newly discovered
2045:University of Minnesota faculty
1546:Jamieson, Stuart (April 2018).
979:UC San Diego School of Medicine
540:pulmonary thromboendarterectomy
224:heart-lung transplant procedure
176:pulmonary thromboendarterectomy
93:Pulmonary thromboendarterectomy
1966:Interview with Stuart Jamieson
1888:. San Diego Zoo Global Press.
765:The Annals of Thoracic Surgery
733:The Annals of Thoracic Surgery
513:Sulpizio Cardiovascular Center
247:Sulpizio Cardiovascular Center
121:The Annals of Thoracic Surgery
91:(CTEPH) can be corrected with
1:
1433:Clinical respiratory medicine
1072:(13): 1364–1365. 1999-09-28.
849:Wolf, Leslie (7 April 1989).
603:. He repaired her penny-size
511:certified and co-founded the
273:), where he was educated at
1564:10.1016/j.healun.2018.01.001
1169:Jamieson, S. W. (May 1974).
899:Stanger, Shelby (May 2011).
309:, in a 43-year-old man with
2055:Stanford University faculty
2030:British transplant surgeons
1882:Irvine, Georgeanne (2018).
1598:www.radcliffecardiology.com
1130:10.1101/cshperspect.a015628
1017:Transplantation Proceedings
945:Valentine, Vincent (2017).
635:Ellis Island Medal of Honor
471:In 1986, Jamieson replaced
142:Ellis Island Medal of Honor
44:1947 (age 76–77)
2071:
1724:10.1016/j.cjca.2011.09.013
1079:10.1161/01.CIR.100.13.1364
740:"Pulmonary endarterectomy"
629:American Heart Association
437:remained intact after the
356:American Heart Association
245:, where he co-founded the
218:. In 1981, he was part of
1464:D.K. Cooper, ed. (1990).
427:alternative blood vessels
170:(born 1947) is a British
156:
99:
28:
2005:Alumni of Falcon College
1548:"Dr. Michael Peter Kaye"
1328:Hamilton, David (2012).
533:pulmonary endarterectomy
253:Early life and education
1050:(subscription required)
710:British Medical Journal
666:, RosettaBooks (2019),
477:University of Minnesota
431:restricted blood supply
399:British Medical Journal
239:University of Minnesota
163:Stuart William Jamieson
2035:White Rhodesian people
1942:professional.heart.org
1792:Pulmonary hypertension
1662:10.1136/heart.89.4.369
1519:Heim, Michael (2004).
1273:10.1002/clc.4960230620
801:Orange County Register
534:
500:
492:
468:
435:coronary blood vessels
423:Eisenmenger's syndrome
321:and difficulties with
299:pulmonary hypertension
262:
172:cardiothoracic surgeon
70:Cardiothoracic surgeon
1790:Kim, Nick H. (2016).
827:"Stuart Jamieson, MD"
648:Selected publications
532:
498:
490:
466:
341:Early surgical career
260:
87:First to report that
569:ventricular function
542:(PTE) performed for
205:hyperacute rejection
1915:The Washington Post
1261:Clinical Cardiology
1257:"Norman E. Shumway"
641:ISHLT Pioneer Award
404:Sir Terence English
385:Jean-Francois Borel
369:Clinical Cardiology
360:Stanford University
228:Stanford University
148:ISHLT Pioneer Award
1224:The New York Times
902:San Diego Magazine
803:. 19 February 2014
535:
525:Heart-lung surgery
505:Michael Peter Kaye
501:
493:
469:
315:Christiaan Barnard
303:C. Walton Lillehei
279:St Mary's Hospital
263:
191:pulmonary arteries
174:, specialising in
23:Stuart W. Jamieson
1868:978-1-85233-873-2
1833:profiles.ucsd.edu
1776:978-1-4377-1617-7
1625:. 23 October 2017
1532:978-0-9744358-1-7
1477:978-94-010-6805-5
1388:978-1-4615-9848-0
1343:978-0-8229-4413-3
855:Los Angeles Times
692:Michael M. Madani
672:978-1-948122-32-0
605:hole in the heart
587:Karen (orangutan)
345:Following 1971's
319:immunosuppression
213:immunosuppressant
160:
159:
76:Years active
2062:
1953:
1952:
1950:
1948:
1934:
1928:
1927:
1925:
1923:
1918:. 27 August 1994
1906:
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1023:(8): 2779–2781.
1012:
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981:. Archived from
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958:
957:
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911:
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846:
835:
834:
829:. Archived from
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699:Journal articles
439:bronchial artery
209:heart transplant
169:
33:
19:
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1175:Transplantation
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909:on 6 June 2023.
898:
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833:on 6 June 2023.
825:Dunning, Joel.
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527:
485:
473:Walton Lillehei
461:
415:
348:Life Magazine's
343:
335:corticosteroids
329:. In addition,
287:
255:
193:in people with
165:
50:
45:
36:
24:
17:
16:British surgeon
12:
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5:
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1960:External links
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1755:
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1656:(4): 369–370.
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1442:978-1455723294
1441:
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1409:. 8 April 2016
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