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AKR7A2

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313: 290: 187: 212: 564: 1772: 40: 319: 218: 2524: 2544: 66: 1196:"Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase" 2002: 1393:"Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins" 1370:
Praml C, Savelyeva L, Perri P, Schwab M (1998). "Cloning of the human aflatoxin B1-aldehyde reductase gene at 1p35-1p36.1 in a region frequently altered in human tumor cells".
1997: 2158: 326: 225: 1812: 2052: 1341:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
1771: 1846: 2087: 787: 2047: 768: 148: 1932: 1875: 2623: 1987: 1176: 2589: 1805: 1751: 1158: 2608: 2082: 2042: 1312:
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
63: 2092: 2059: 1264: 312: 2618: 2186: 1947: 1860: 1612:"Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy" 1002: 995: 2243: 1942: 1842: 1565:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
289: 1798: 1246: 1696:"Synthesis and catabolism of gamma-hydroxybutyrate in SH-SY5Y human neuroblastoma cells: role of the aldo-keto reductase AKR7A2" 1855: 1145: 1124: 2181: 2007: 2399: 1270: 1141: 1992: 211: 186: 1489:"Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells" 1120: 2020: 128: 2153: 1917: 325: 224: 2514: 1922: 318: 217: 2384: 2582: 2500: 2487: 2474: 2461: 2448: 2435: 2422: 2196: 2168: 2140: 2102: 2069: 1972: 1838: 1744: 2394: 2348: 2291: 1962: 1829: 832: 136: 119:, AFAR, AFAR1, AFB1-AR1, AKR7, aldo-keto reductase family 7, member A2, aldo-keto reductase family 7 member A2 1524:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" 2296: 2120: 1927: 813: 2012: 1825: 2317: 2236: 2205: 1967: 1865: 2389: 2575: 1982: 1977: 1937: 1737: 1664: 1574: 1447: 200: 1790: 2353: 1870: 1276: 1084: 953: 906: 115: 17: 2286: 1639: 1598: 1056: 160: 1436:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 978: 957: 927: 902: 563: 2613: 1957: 1952: 1717: 1682: 1631: 1590: 1553: 1510: 1475: 1422: 1379: 1358: 1329: 1283: 1225: 108: 56: 2332: 2327: 2301: 2229: 2125: 1912: 1707: 1672: 1623: 1582: 1543: 1535: 1500: 1465: 1455: 1412: 1404: 1350: 1321: 1247:"Entrez Gene: AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)" 1215: 1207: 405: 336: 280: 235: 156: 2379: 2363: 2276: 2130: 2115: 380: 1668: 1578: 1451: 39: 2559: 2528: 2417: 2358: 1821: 1417: 1392: 1220: 1195: 1088: 1548: 1523: 1470: 1435: 1354: 702: 697: 692: 687: 682: 677: 661: 656: 651: 646: 630: 625: 620: 615: 610: 605: 2602: 2322: 2281: 1325: 1292: 592: 1643: 2555: 2271: 1611: 1602: 398: 177: 140: 164: 2495: 2430: 2266: 1181:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
2523: 481: 2073: 2025: 297: 194: 144: 2469: 2443: 2144: 732: 541: 419: 364: 351: 263: 250: 152: 2030: 1721: 1712: 1695: 1686: 1635: 1594: 1557: 1514: 1505: 1488: 1479: 1460: 1426: 1383: 1362: 1333: 1229: 1042: 1037: 1092: 1026: 877: 858: 1677: 1652: 1586: 2172: 1885: 1539: 1408: 1297: 1287: 844: 799: 1211: 85: 2482: 2252: 2210: 2106: 1900: 1895: 1890: 1880: 1780:: STRUCTURE OF THE AFLATOXIN ALDEHYDE REDUCTASE IN COMPLEX WITH NADPH 1096: 1062: 1010: 754: 2543: 1627: 2456: 2035: 1653:"The DNA sequence and biological annotation of human chromosome 1" 1066: 1296:(Human Aflatoxin B1 aldehyde reductase member 2 (AKR7A2)) at the 717: 713: 2551: 1073: 132: 2225: 1794: 1733: 572: 1729: 1282:
Overview of all the structural information available in the
2003:
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1434:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
2221: 388: 2563: 1522:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1194:
Ireland LS, Harrison DJ, Neal GE, Hayes JD (Aug 1998).
2512: 1694:
Lyon RC, Johnston SM, Watson DG, et al. (2007).
1651:
Gregory SG, Barlow KF, McLay KE, et al. (2006).
1610:
Jordanova A, Irobi J, Thomas FP, et al. (2006).
553: 2408: 2372: 2341: 2310: 2259: 2195: 2167: 2139: 2101: 2068: 1998:
Malate dehydrogenase (oxaloacetate-decarboxylating)
1837: 1391:Kelly VP, Sherratt PJ, Crouch DH, Hayes JD (2002). 971: 946: 920: 895: 2159:Vitamin-K-epoxide reductase (warfarin-insensitive) 1137: 1135: 1133: 1116: 1114: 1112: 335: 234: 27:Protein-coding gene in the species Homo sapiens 1142:GRCm38: Ensembl release 89: ENSMUSG00000028743 2583: 2237: 1806: 1745: 8: 621:phenanthrene-9,10-epoxide hydrolase activity 1121:GRCh38: Ensembl release 89: ENSG00000053371 2590: 2576: 2244: 2230: 2222: 2088:D-lactate dehydrogenase (cytochrome c-553) 1813: 1799: 1791: 1752: 1738: 1730: 728: 588: 376: 275: 172: 74: 1711: 1676: 1547: 1504: 1469: 1459: 1416: 1219: 1933:D-malate dehydrogenase (decarboxylating) 1241: 1239: 2519: 1767: 1487:Praml C, Savelyeva L, Schwab M (2003). 1108: 606:alditol:NADP+ 1-oxidoreductase activity 1988:Malate dehydrogenase (decarboxylating) 1087:, such as AKR7A2, are involved in the 516:crypt of lieberkuhn of small intestine 29: 340: 301: 296: 239: 198: 193: 7: 2540: 2538: 2083:D-lactate dehydrogenase (cytochrome) 2093:Mannitol dehydrogenase (cytochrome) 683:cellular aldehyde metabolic process 626:aldo-keto reductase (NADP) activity 18:Succinic semialdehyde dehydrogenase 2187:Quinoprotein glucose dehydrogenase 1948:Glycerol-3-phosphate dehydrogenase 1861:3-hydroxybutyryl-CoA dehydrogenase 968: 943: 917: 892: 868: 849: 823: 804: 778: 759: 558: 476: 414: 393: 25: 1943:Glucose-6-phosphate dehydrogenase 2542: 2522: 1770: 562: 324: 317: 311: 288: 223: 216: 210: 185: 38: 1856:3-hydroxyacyl-CoA dehydrogenase 2182:Malate dehydrogenase (quinone) 2008:Phosphogluconate dehydrogenase 698:carbohydrate metabolic process 688:daunorubicin metabolic process 573:More reference expression data 542:More reference expression data 1: 2624:Human chromosome 1 gene stubs 1355:10.1016/S0378-1119(97)00411-3 693:doxorubicin metabolic process 309: 208: 2562:. You can help Knowledge by 2021:Hydroxysteroid dehydrogenase 1993:Malate dehydrogenase (NADP+) 1440:Proc. Natl. Acad. Sci. U.S.A 1326:10.1016/0378-1119(94)90802-8 678:xenobiotic metabolic process 2609:Genes on human chromosome 1 2154:Vitamin K epoxide reductase 1923:Carbohydrate dehydrogenases 1918:Beta-Ketoacyl ACP reductase 2640: 2537: 1275:gene details page in the 611:electron transfer activity 430:mucosa of transverse colon 2619:Gamma-Hydroxybutyric acid 2400:Michaelis–Menten kinetics 1973:L-threonine dehydrogenase 1765: 1177:"Mouse PubMed Reference:" 1159:"Human PubMed Reference:" 1041: 1036: 1032: 1025: 1009: 1003:Chr 4: 139.04 – 139.05 Mb 990: 975: 950: 939: 924: 899: 888: 875: 871: 856: 852: 843: 830: 826: 811: 807: 798: 785: 781: 766: 762: 753: 738: 731: 727: 711: 591: 587: 570: 561: 552: 539: 488: 479: 426: 417: 387: 379: 375: 358: 345: 308: 287: 278: 274: 257: 244: 207: 184: 175: 171: 126: 123: 113: 106: 101: 82: 77: 60: 55: 50: 46: 37: 32: 2292:Diffusion-limited enzyme 1963:Isocitrate dehydrogenase 703:electron transport chain 2121:L-gulonolactone oxidase 1928:Carnitine dehydrogenase 1826:alcohol oxidoreductases 616:oxidoreductase activity 520:external carotid artery 512:internal carotid artery 2013:Sorbitol dehydrogenase 1713:10.1074/jbc.M702465200 1506:10.1038/sj.onc.1206684 1461:10.1073/pnas.242603899 996:Chr 1: 19.3 – 19.31 Mb 2385:Eadie–Hofstee diagram 2318:Allosteric regulation 2206:Choline dehydrogenase 1968:Lactate dehydrogenase 1866:Alcohol dehydrogenase 657:extracellular exosome 2395:Lineweaver–Burk plot 1983:Malate dehydrogenase 1978:L-xylulose reductase 1938:DXP reductoisomerase 1269:genome location and 1085:Aldo-keto reductases 442:right adrenal cortex 342:4 D3|4 70.64 cM 303:Chromosome 4 (mouse) 201:Chromosome 1 (human) 78:List of PDB id codes 51:Available structures 1871:Aldo-keto reductase 1678:10.1038/nature04727 1669:2006Natur.441..315G 1587:10.1038/nature04209 1579:2005Natur.437.1173R 1452:2002PNAS...9916899M 1277:UCSC Genome Browser 466:canal of the cervix 458:left adrenal cortex 438:right adrenal gland 2550:This article on a 2354:Enzyme superfamily 2287:Enzyme promiscuity 1540:10.1101/gr.2596504 1409:10.1042/BJ20020342 1069:is encoded by the 1057:aldehyde reductase 833:ENSMUSG00000028743 671:Biological process 640:Cellular component 599:Molecular function 500:left lobe of liver 450:left adrenal gland 446:right uterine tube 165:AKR7A2 - orthologs 2571: 2570: 2510: 2509: 2219: 2218: 2199:: other acceptors 2175:/similar acceptor 1958:IMP dehydrogenase 1953:HMG-CoA reductase 1788: 1787: 1446:(26): 16899–903. 1212:10.1042/bj3320021 1052: 1051: 1048: 1047: 1021: 1020: 986: 985: 965: 964: 935: 934: 914: 913: 884: 883: 865: 864: 839: 838: 820: 819: 794: 793: 775: 774: 723: 722: 583: 582: 579: 578: 548: 547: 535: 534: 473: 472: 371: 370: 270: 269: 97: 96: 93: 92: 61:Ortholog search: 16:(Redirected from 2631: 2592: 2585: 2578: 2546: 2539: 2527: 2526: 2518: 2390:Hanes–Woolf plot 2333:Enzyme activator 2328:Enzyme inhibitor 2302:Enzyme catalysis 2246: 2239: 2232: 2223: 2126:Xanthine oxidase 1913:Aldose reductase 1815: 1808: 1801: 1792: 1774: 1754: 1747: 1740: 1731: 1725: 1715: 1706:(36): 25986–92. 1690: 1680: 1663:(7091): 315–21. 1647: 1606: 1573:(7062): 1173–8. 1561: 1551: 1518: 1508: 1483: 1473: 1463: 1430: 1420: 1403:(Pt 3): 847–61. 1387: 1366: 1337: 1251: 1250: 1243: 1234: 1233: 1223: 1191: 1185: 1184: 1173: 1167: 1166: 1155: 1149: 1139: 1128: 1118: 1034: 1033: 1005: 998: 981: 969: 960: 944: 940:RefSeq (protein) 930: 918: 909: 893: 869: 850: 824: 805: 779: 760: 729: 589: 575: 566: 559: 544: 484: 482:Top expressed in 477: 422: 420:Top expressed in 415: 394: 377: 367: 354: 343: 328: 321: 315: 304: 292: 276: 266: 253: 242: 227: 220: 214: 203: 189: 173: 167: 118: 111: 88: 75: 69: 48: 47: 42: 30: 21: 2639: 2638: 2634: 2633: 2632: 2630: 2629: 2628: 2599: 2598: 2597: 2596: 2535: 2533: 2521: 2513: 2511: 2506: 2418:Oxidoreductases 2404: 2380:Enzyme kinetics 2368: 2364:List of enzymes 2337: 2306: 2277:Catalytic triad 2255: 2250: 2220: 2215: 2191: 2163: 2135: 2131:Alcohol oxidase 2116:Glucose oxidase 2097: 2064: 1833: 1822:Oxidoreductases 1819: 1789: 1784: 1781: 1775: 1761: 1758: 1728: 1693: 1650: 1609: 1564: 1534:(10B): 2121–7. 1521: 1499:(30): 4765–73. 1486: 1433: 1390: 1369: 1349:(1–2): 149–56. 1340: 1311: 1307: 1305:Further reading 1260: 1255: 1254: 1245: 1244: 1237: 1193: 1192: 1188: 1175: 1174: 1170: 1157: 1156: 1152: 1140: 1131: 1119: 1110: 1105: 1082: 1043:View/Edit Mouse 1038:View/Edit Human 1001: 994: 991:Location (UCSC) 977: 956: 952: 926: 905: 901: 814:ENSG00000053371 707: 666: 652:Golgi apparatus 635: 631:protein binding 571: 540: 531: 526: 524:right ventricle 522: 518: 514: 510: 506: 502: 498: 496:proximal tubule 494: 480: 469: 464: 460: 456: 452: 448: 444: 440: 436: 432: 418: 362: 349: 341: 331: 330: 329: 322: 302: 279:Gene location ( 261: 248: 240: 230: 229: 228: 221: 199: 176:Gene location ( 127: 114: 107: 84: 62: 28: 23: 22: 15: 12: 11: 5: 2637: 2635: 2627: 2626: 2621: 2616: 2611: 2601: 2600: 2595: 2594: 2587: 2580: 2572: 2569: 2568: 2547: 2532: 2531: 2508: 2507: 2505: 2504: 2491: 2478: 2465: 2452: 2439: 2426: 2412: 2410: 2406: 2405: 2403: 2402: 2397: 2392: 2387: 2382: 2376: 2374: 2370: 2369: 2367: 2366: 2361: 2356: 2351: 2345: 2343: 2342:Classification 2339: 2338: 2336: 2335: 2330: 2325: 2320: 2314: 2312: 2308: 2307: 2305: 2304: 2299: 2294: 2289: 2284: 2279: 2274: 2269: 2263: 2261: 2257: 2256: 2251: 2249: 2248: 2241: 2234: 2226: 2217: 2216: 2214: 2213: 2208: 2202: 2200: 2193: 2192: 2190: 2189: 2184: 2178: 2176: 2165: 2164: 2162: 2161: 2156: 2150: 2148: 2137: 2136: 2134: 2133: 2128: 2123: 2118: 2112: 2110: 2099: 2098: 2096: 2095: 2090: 2085: 2079: 2077: 2066: 2065: 2063: 2062: 2057: 2056: 2055: 2050: 2040: 2039: 2038: 2033: 2016: 2015: 2010: 2005: 2000: 1995: 1990: 1985: 1980: 1975: 1970: 1965: 1960: 1955: 1950: 1945: 1940: 1935: 1930: 1925: 1920: 1915: 1910: 1909: 1908: 1903: 1898: 1893: 1888: 1883: 1878: 1868: 1863: 1858: 1852: 1850: 1835: 1834: 1820: 1818: 1817: 1810: 1803: 1795: 1786: 1785: 1783: 1782: 1776: 1769: 1766: 1763: 1762: 1759: 1757: 1756: 1749: 1742: 1734: 1727: 1726: 1691: 1648: 1628:10.1038/ng1727 1622:(2): 197–202. 1607: 1562: 1519: 1484: 1431: 1388: 1378:(22): 5014–8. 1367: 1338: 1320:(1–2): 171–4. 1308: 1306: 1303: 1302: 1301: 1280: 1259: 1258:External links 1256: 1253: 1252: 1235: 1186: 1168: 1150: 1129: 1107: 1106: 1104: 1101: 1089:detoxification 1081: 1078: 1050: 1049: 1046: 1045: 1040: 1030: 1029: 1023: 1022: 1019: 1018: 1016: 1014: 1007: 1006: 999: 992: 988: 987: 984: 983: 973: 972: 966: 963: 962: 948: 947: 941: 937: 936: 933: 932: 922: 921: 915: 912: 911: 897: 896: 890: 886: 885: 882: 881: 873: 872: 866: 863: 862: 854: 853: 847: 841: 840: 837: 836: 828: 827: 821: 818: 817: 809: 808: 802: 796: 795: 792: 791: 783: 782: 776: 773: 772: 764: 763: 757: 751: 750: 745: 740: 736: 735: 725: 724: 721: 720: 709: 708: 706: 705: 700: 695: 690: 685: 680: 674: 672: 668: 667: 665: 664: 659: 654: 649: 643: 641: 637: 636: 634: 633: 628: 623: 618: 613: 608: 602: 600: 596: 595: 585: 584: 581: 580: 577: 576: 568: 567: 556: 550: 549: 546: 545: 537: 536: 533: 532: 530: 529: 525: 521: 517: 513: 509: 505: 501: 497: 493: 489: 486: 485: 474: 471: 470: 468: 467: 463: 459: 455: 454:jejunal mucosa 451: 447: 443: 439: 435: 431: 427: 424: 423: 411: 410: 402: 391: 385: 384: 381:RNA expression 373: 372: 369: 368: 360: 356: 355: 347: 344: 339: 333: 332: 323: 316: 310: 306: 305: 300: 294: 293: 285: 284: 272: 271: 268: 267: 259: 255: 254: 246: 243: 238: 232: 231: 222: 215: 209: 205: 204: 197: 191: 190: 182: 181: 169: 168: 125: 121: 120: 112: 104: 103: 99: 98: 95: 94: 91: 90: 80: 79: 71: 70: 59: 53: 52: 44: 43: 35: 34: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2636: 2625: 2622: 2620: 2617: 2615: 2612: 2610: 2607: 2606: 2604: 2593: 2588: 2586: 2581: 2579: 2574: 2573: 2567: 2565: 2561: 2557: 2553: 2548: 2545: 2541: 2536: 2530: 2525: 2520: 2516: 2502: 2498: 2497: 2492: 2489: 2485: 2484: 2479: 2476: 2472: 2471: 2466: 2463: 2459: 2458: 2453: 2450: 2446: 2445: 2440: 2437: 2433: 2432: 2427: 2424: 2420: 2419: 2414: 2413: 2411: 2407: 2401: 2398: 2396: 2393: 2391: 2388: 2386: 2383: 2381: 2378: 2377: 2375: 2371: 2365: 2362: 2360: 2359:Enzyme family 2357: 2355: 2352: 2350: 2347: 2346: 2344: 2340: 2334: 2331: 2329: 2326: 2324: 2323:Cooperativity 2321: 2319: 2316: 2315: 2313: 2309: 2303: 2300: 2298: 2295: 2293: 2290: 2288: 2285: 2283: 2282:Oxyanion hole 2280: 2278: 2275: 2273: 2270: 2268: 2265: 2264: 2262: 2258: 2254: 2247: 2242: 2240: 2235: 2233: 2228: 2227: 2224: 2212: 2209: 2207: 2204: 2203: 2201: 2198: 2194: 2188: 2185: 2183: 2180: 2179: 2177: 2174: 2170: 2166: 2160: 2157: 2155: 2152: 2151: 2149: 2146: 2142: 2138: 2132: 2129: 2127: 2124: 2122: 2119: 2117: 2114: 2113: 2111: 2108: 2104: 2100: 2094: 2091: 2089: 2086: 2084: 2081: 2080: 2078: 2075: 2071: 2067: 2061: 2058: 2054: 2051: 2049: 2046: 2045: 2044: 2041: 2037: 2034: 2032: 2029: 2028: 2027: 2024: 2022: 2018: 2017: 2014: 2011: 2009: 2006: 2004: 2001: 1999: 1996: 1994: 1991: 1989: 1986: 1984: 1981: 1979: 1976: 1974: 1971: 1969: 1966: 1964: 1961: 1959: 1956: 1954: 1951: 1949: 1946: 1944: 1941: 1939: 1936: 1934: 1931: 1929: 1926: 1924: 1921: 1919: 1916: 1914: 1911: 1907: 1904: 1902: 1899: 1897: 1894: 1892: 1889: 1887: 1884: 1882: 1879: 1877: 1874: 1873: 1872: 1869: 1867: 1864: 1862: 1859: 1857: 1854: 1853: 1851: 1848: 1844: 1840: 1836: 1831: 1827: 1823: 1816: 1811: 1809: 1804: 1802: 1797: 1796: 1793: 1779: 1773: 1768: 1764: 1755: 1750: 1748: 1743: 1741: 1736: 1735: 1732: 1723: 1719: 1714: 1709: 1705: 1701: 1700:J. Biol. Chem 1697: 1692: 1688: 1684: 1679: 1674: 1670: 1666: 1662: 1658: 1654: 1649: 1645: 1641: 1637: 1633: 1629: 1625: 1621: 1617: 1613: 1608: 1604: 1600: 1596: 1592: 1588: 1584: 1580: 1576: 1572: 1568: 1563: 1559: 1555: 1550: 1545: 1541: 1537: 1533: 1529: 1525: 1520: 1516: 1512: 1507: 1502: 1498: 1494: 1490: 1485: 1481: 1477: 1472: 1467: 1462: 1457: 1453: 1449: 1445: 1441: 1437: 1432: 1428: 1424: 1419: 1414: 1410: 1406: 1402: 1398: 1394: 1389: 1385: 1381: 1377: 1373: 1368: 1364: 1360: 1356: 1352: 1348: 1344: 1339: 1335: 1331: 1327: 1323: 1319: 1315: 1310: 1309: 1304: 1299: 1295: 1294: 1289: 1285: 1281: 1278: 1274: 1273: 1268: 1267: 1262: 1261: 1257: 1248: 1242: 1240: 1236: 1231: 1227: 1222: 1217: 1213: 1209: 1205: 1201: 1197: 1190: 1187: 1182: 1178: 1172: 1169: 1164: 1160: 1154: 1151: 1147: 1143: 1138: 1136: 1134: 1130: 1126: 1122: 1117: 1115: 1113: 1109: 1102: 1100: 1098: 1094: 1090: 1086: 1079: 1077: 1075: 1072: 1068: 1064: 1060: 1058: 1055:Aflatoxin B1 1044: 1039: 1035: 1031: 1028: 1024: 1017: 1015: 1012: 1008: 1004: 1000: 997: 993: 989: 982: 980: 974: 970: 967: 961: 959: 955: 949: 945: 942: 938: 931: 929: 923: 919: 916: 910: 908: 904: 898: 894: 891: 889:RefSeq (mRNA) 887: 880: 879: 874: 870: 867: 861: 860: 855: 851: 848: 846: 842: 835: 834: 829: 825: 822: 816: 815: 810: 806: 803: 801: 797: 790: 789: 784: 780: 777: 771: 770: 765: 761: 758: 756: 752: 749: 746: 744: 741: 737: 734: 730: 726: 719: 715: 710: 704: 701: 699: 696: 694: 691: 689: 686: 684: 681: 679: 676: 675: 673: 670: 669: 663: 660: 658: 655: 653: 650: 648: 645: 644: 642: 639: 638: 632: 629: 627: 624: 622: 619: 617: 614: 612: 609: 607: 604: 603: 601: 598: 597: 594: 593:Gene ontology 590: 586: 574: 569: 565: 560: 557: 555: 551: 543: 538: 527: 523: 519: 515: 511: 507: 503: 499: 495: 491: 490: 487: 483: 478: 475: 465: 461: 457: 453: 449: 445: 441: 437: 433: 429: 428: 425: 421: 416: 413: 412: 409: 407: 403: 401: 400: 396: 395: 392: 390: 386: 382: 378: 374: 366: 361: 357: 353: 348: 338: 334: 327: 320: 314: 307: 299: 295: 291: 286: 282: 277: 273: 265: 260: 256: 252: 247: 237: 233: 226: 219: 213: 206: 202: 196: 192: 188: 183: 179: 174: 170: 166: 162: 158: 154: 150: 146: 142: 138: 134: 130: 122: 117: 110: 105: 100: 89: 87: 81: 76: 73: 72: 68: 65: 58: 54: 49: 45: 41: 36: 31: 19: 2564:expanding it 2556:chromosome 1 2549: 2534: 2496:Translocases 2493: 2480: 2467: 2454: 2441: 2431:Transferases 2428: 2415: 2272:Binding site 2019: 1905: 1777: 1703: 1699: 1660: 1656: 1619: 1615: 1570: 1566: 1531: 1527: 1496: 1492: 1443: 1439: 1400: 1396: 1375: 1371: 1346: 1342: 1317: 1313: 1291: 1271: 1265: 1206:(1): 21–34. 1203: 1199: 1189: 1180: 1171: 1162: 1153: 1083: 1070: 1054: 1053: 976: 954:NP_001307908 951: 925: 907:NM_001320979 900: 876: 857: 831: 812: 786: 767: 747: 742: 528:motor neuron 508:human kidney 492:right kidney 462:human kidney 404: 397: 363:139,045,737 350:139,038,055 124:External IDs 83: 2267:Active site 2147:as acceptor 1760:PDB gallery 504:Paneth cell 262:19,312,144 249:19,303,965 102:Identifiers 2603:Categories 2470:Isomerases 2444:Hydrolases 2311:Regulation 2074:cytochrome 1616:Nat. Genet 1528:Genome Res 1397:Biochem. J 1372:Cancer Res 1148:, May 2017 1127:, May 2017 1103:References 408:(ortholog) 145:HomoloGene 2554:on human 2349:EC number 2145:disulfide 1200:Biochem J 1093:aldehydes 979:NP_079613 958:NP_003680 928:NM_025337 903:NM_003689 733:Orthologs 647:cytoplasm 153:GeneCards 2614:EC 1.1.1 2373:Kinetics 2297:Cofactor 2260:Activity 2109:acceptor 2076:acceptor 2053:11β-HSD2 2048:11β-HSD1 1849:acceptor 1722:17591773 1687:16710414 1644:16668375 1636:16429158 1595:16189514 1558:15489334 1515:12879023 1493:Oncogene 1480:12477932 1427:12071861 1144:– 1123:– 1080:Function 1065:that in 1059:member 2 1027:Wikidata 712:Sources: 434:duodenum 2529:Biology 2483:Ligases 2253:Enzymes 2173:quinone 1665:Bibcode 1603:4427026 1575:Bibcode 1448:Bibcode 1418:1222835 1384:9823300 1363:9373149 1334:8125298 1298:PDBe-KB 1288:UniProt 1230:9576847 1221:1219447 1146:Ensembl 1125:Ensembl 1097:ketones 845:UniProt 800:Ensembl 739:Species 718:QuickGO 662:cytosol 383:pattern 241:1p36.13 109:Aliases 2515:Portal 2457:Lyases 2211:L2HGDH 2197:1.1.99 2107:oxygen 2031:3β-HSD 1720:  1685:  1657:Nature 1642:  1634:  1601:  1593:  1567:Nature 1556:  1549:528928 1546:  1513:  1478:  1471:139241 1468:  1425:  1415:  1382:  1361:  1332:  1293:O43488 1272:AKR7A2 1266:AKR7A2 1263:Human 1228:  1218:  1071:AKR7A2 1067:humans 1063:enzyme 1061:is an 1013:search 1011:PubMed 878:Q8CG76 859:O43488 788:110198 755:Entrez 554:BioGPS 157:AKR7A2 141:107796 133:603418 116:AKR7A2 33:AKR7A2 2558:is a 2409:Types 2169:1.1.5 2141:1.1.4 2103:1.1.3 2070:1.1.2 2036:NSDHL 1839:1.1.1 1640:S2CID 1599:S2CID 748:Mouse 743:Human 714:Amigo 406:Mouse 399:Human 346:Start 281:Mouse 245:Start 178:Human 2560:stub 2552:gene 2501:list 2494:EC7 2488:list 2481:EC6 2475:list 2468:EC5 2462:list 2455:EC4 2449:list 2442:EC3 2436:list 2429:EC2 2423:list 2416:EC1 1886:1B10 1847:NADP 1832:1.1) 1778:2bp1 1718:PMID 1683:PMID 1632:PMID 1591:PMID 1554:PMID 1511:PMID 1476:PMID 1423:PMID 1380:PMID 1359:PMID 1343:Gene 1330:PMID 1314:Gene 1286:for 1226:PMID 1095:and 1074:gene 769:8574 389:Bgee 337:Band 298:Chr. 236:Band 195:Chr. 149:2737 129:OMIM 86:2BP1 67:RCSB 64:PDBe 2060:17β 2043:11β 1906:7A2 1901:1C4 1896:1C3 1891:1C1 1881:1B1 1876:1A1 1843:NAD 1708:doi 1704:282 1673:doi 1661:441 1624:doi 1583:doi 1571:437 1544:PMC 1536:doi 1501:doi 1466:PMC 1456:doi 1413:PMC 1405:doi 1401:366 1351:doi 1347:200 1322:doi 1318:138 1284:PDB 1216:PMC 1208:doi 1204:332 1091:of 359:End 258:End 161:OMA 137:MGI 57:PDB 2605:: 2171:: 2143:: 2105:: 2072:: 2026:3β 1841:: 1830:EC 1824:: 1716:. 1702:. 1698:. 1681:. 1671:. 1659:. 1655:. 1638:. 1630:. 1620:38 1618:. 1614:. 1597:. 1589:. 1581:. 1569:. 1552:. 1542:. 1532:14 1530:. 1526:. 1509:. 1497:22 1495:. 1491:. 1474:. 1464:. 1454:. 1444:99 1442:. 1438:. 1421:. 1411:. 1399:. 1395:. 1376:58 1374:. 1357:. 1345:. 1328:. 1316:. 1290:: 1238:^ 1224:. 1214:. 1202:. 1198:. 1179:. 1161:. 1132:^ 1111:^ 1099:. 1076:. 716:/ 365:bp 352:bp 264:bp 251:bp 159:; 155:: 151:; 147:: 143:; 139:: 135:; 131:: 2591:e 2584:t 2577:v 2566:. 2517:: 2503:) 2499:( 2490:) 2486:( 2477:) 2473:( 2464:) 2460:( 2451:) 2447:( 2438:) 2434:( 2425:) 2421:( 2245:e 2238:t 2231:v 2023:: 1845:/ 1828:( 1814:e 1807:t 1800:v 1753:e 1746:t 1739:v 1724:. 1710:: 1689:. 1675:: 1667:: 1646:. 1626:: 1605:. 1585:: 1577:: 1560:. 1538:: 1517:. 1503:: 1482:. 1458:: 1450:: 1429:. 1407:: 1386:. 1365:. 1353:: 1336:. 1324:: 1300:. 1279:. 1249:. 1232:. 1210:: 1183:. 1165:. 283:) 180:) 163:: 20:)

Index

Succinic semialdehyde dehydrogenase

PDB
PDBe
RCSB
2BP1
Aliases
AKR7A2
OMIM
603418
MGI
107796
HomoloGene
2737
GeneCards
AKR7A2
OMA
AKR7A2 - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for AKR7A2
Genomic location for AKR7A2
Band
bp
bp
Mouse
Chromosome 4 (mouse)

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