204:
180:
192:
1296:
Raymond; Oliva-Hemker, Maria; Pare, Pierre; Wild, Gary E.; Rioux, John D.; Yang, Huiying; Duerr, Richard H.; Cho, Judy H.; Steinhart, A. Hillary; Brant, Steven R.; Silverberg, Mark S. (2006). "Inflammatory Bowel
Disease Characteristics Among African Americans, Hispanics, and Non-Hispanic Whites: Characterization of a Large North American Cohort".
53:
137:
nodules can appear anywhere on the body, but the most common sites are the shins, arms, thighs, and torso. Each nodule typically disappears after around two weeks, though new ones may continue to form for up to six or eight weeks. A new nodule usually appears red and is hot and firm to the touch. The
1295:
Nguyen, Geoffrey C.; Torres, Esther A.; Regueiro, Miguel; Bromfield, Gillian; Bitton, Alain; Stempak, Joanne; Dassopoulos, Themistocles; Schumm, Philip; Gregory, Federico J.; Griffiths, Anne M.; Hanauer, Stephen B.; Hanson, Jennifer; Harris, Mary L.; Kane, Sunanda V.; Orkwis, Heather Kiraly; Lahaie,
471:
can be taken and examined microscopically to confirm an uncertain diagnosis. Microscopic examination usually reveals a neutrophilic infiltrate surrounding capillaries that results in septal thickening, with fibrotic changes in the fat around blood vessels. A characteristic microscopic finding is
138:
redness starts to fade and it gradually becomes softer and smaller until it disappears. Each nodule usually heals completely without scarring over the course of about two weeks. Joint pain and inflammation sometimes continue for several weeks or months after the nodules appear.
526:. Treatment should focus on the underlying cause. Symptoms can be treated with bed rest, leg elevation, compressive bandages, wet dressings, and nonsteroidal anti-inflammatory agents (NSAIDs). NSAIDs are usually more effective at the onset of EN versus with chronic disease.
458:
Erythema nodosum is probably a delayed hypersensitivity reaction to a variety of antigens. Although circulating immune complexes have been demonstrated in patients with inflammatory bowel disease, they have not been found in idiopathic or uncomplicated cases.
1667:
1652:
544:
has been used successfully in the treatment of
Erythema nodosum leprosum, and it was approved by the U.S. FDA for this use in July 1998. According to a 2009 meta-analysis, there is some evidence of benefit for both thalidomide and
1771:
100:, resulting in painful red/blue lumps or nodules that are usually seen symmetrically on both shins, on the thighs, arms, and elsewhere. It can be caused by a variety of conditions but 20 to 50% of cases are
1764:
1757:
3262:
1339:
GarcĂa-PorrĂşa, Carlos; González-Gay, Miguel A.; Vázquez-Caruncho, Manuel; LĂłpez-Lazaro, Luis; Lueiro, Mercedes; Fernández, Maria L.; Alvarez-Ferreira, Javier; Pujol, RamĂłn M. (2000).
3564:
3524:
522:
Erythema nodosum is self-limiting and usually resolves itself within 3–6 weeks. A recurring form does exist, and in children, it is attributed to repeated infections with
2852:
1558:
Van Veen, Natasja HJ; Lockwood, Diana NJ; van Brakel, Wim H; Ramirez Jr, Jose; Richardus, Jan
Hendrik (8 July 2009). "Interventions for erythema nodosum leprosum".
2264:
498:
The ESR is initially very high and falls as the nodules of erythema nodosum. The ASO titer is high in cases associated with a streptococcal throat infection. A
3569:
3404:
3255:
203:
3143:
3017:
3337:
864:
Mert, Ali; Ozaras, Resat; Tabak, Fehmi; Pekmezci, Salih; Demirkesen, Cuyan; Ozturk, Recep (2009). "Erythema
Nodosum: An Experience of 10 Years".
3248:
2571:
179:
450:
for causes is SORE SHINS (Streptococci, OCP, Rickettsia, Eponymous (Behçet), Sulfonamides, Hansen's
Disease (Leprosy), IBD, NHL, Sarcoidosis.
1242:
1217:
975:
845:
817:
696:
628:
475:
Additional evaluation should be performed to determine the underlying cause of erythema nodosum. This may include a full blood count (FBC),
3514:
2845:
1447:
Yurdakul, Sebahattin; Mat, Cem; Tüzün, Yalçin; Özyazgan, Yilmaz; Hamuryudan, Vedat; Uysal, Ömer; Şenocak, Mustafa; Yazici, Hasan (2001).
3303:
3047:
3463:
2353:
649:
2254:
1271:
3364:
2954:
2931:
2363:
2838:
1465:
1448:
172:), a rare form of chronic erythema nodosum characterized by asymmetrical nodules that are mildly tender and migrate over time.
3519:
2926:
2322:
1948:
476:
3473:
1357:
1340:
3200:
3161:
3052:
2515:
2206:
2043:
3121:
2058:
3554:
3483:
3431:
2892:
2682:
2437:
2128:
3359:
1090:
Bohn, S; BĂĽchner, S; Itin, P (1997). "Erythema nodosum: 112 cases. Epidemiology, clinical aspects and histopathology".
3205:
3181:
2432:
1963:
1918:
191:
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3126:
2987:
2785:
2505:
594:
3478:
3347:
3225:
3116:
3111:
2707:
447:
411:
61:
3419:
3369:
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2550:
2196:
2133:
2028:
1686:
574:
480:
286:
3498:
3318:
3176:
2919:
2815:
2510:
2229:
2201:
1831:
384:
243:
3488:
3414:
3323:
3308:
2790:
2702:
2018:
379:
272:
333:
3075:
2992:
2936:
2692:
2619:
2307:
1841:
1821:
292:
265:
17:
121:, and aching joints. Some people also experience stiffness or swelling in the joints and weight loss.
3354:
3220:
3070:
3027:
3022:
2977:
2038:
1836:
1811:
326:
304:
104:. It typically resolves spontaneously within 30 days. It is common in young people aged 12–20 years.
1749:
158:(bleeding under the skin) occurs with an erythema nodosum lesion, causing the lesion to look like a
3393:
3342:
3166:
3098:
3042:
2997:
2760:
2697:
2672:
2646:
2500:
2478:
2073:
2033:
1953:
1943:
1671:
511:
429:
315:
134:
3559:
3383:
3379:
3313:
3037:
3032:
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2902:
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2473:
2358:
2317:
2191:
2186:
2181:
2008:
1478:
1321:
889:
790:
492:
309:
298:
101:
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radial granulomas, well-defined nodular aggregates of histiocytes surrounding a stellate cleft.
345:
146:
3298:
3153:
2876:
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2373:
2249:
2244:
2123:
2097:
2023:
2013:
1851:
1826:
1726:
1697:
1615:
1571:
1513:
1470:
1429:
1406:
Mat, C.; Yurdakul, S; Uysal, S; Gogus, F; Ozyazgan, Y; Uysal, O; Fresko, I; Yazici, H (2005).
1362:
1313:
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1213:
1187:
1138:
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130:
68:
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1419:
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529:
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2063:
1908:
1846:
1589:
657:
569:
The term, Subacute
Migratory Panniculitis of Vilanova and Piñol, was named after the two
991:
Budden, Heidi; Ulloa-Gutierrez, Rolando; Dobson, Simon; Scheifele, David (August 2007).
761:"Erythema nodosum and erythema induratum (nodular vasculitis): Diagnosis and management"
117:
The first signs of erythema nodosum are often flu-like symptoms such as a fever, cough,
2949:
2914:
2810:
2800:
2717:
2259:
2087:
1182:
1157:
967:
935:
908:
533:
443:
histocompatibility antigen, which is present in 65% of patients with erythema nodosum.
1680:
1676:
1380:
3548:
3445:
3103:
2795:
2770:
2725:
2687:
2555:
2422:
2282:
2234:
2166:
2138:
1309:
777:
760:
561:. It is most common in the ages of 20–30, and affects women 3–6 times more than men.
523:
1482:
893:
794:
3280:
3210:
3132:
2740:
2312:
2292:
2107:
2102:
2092:
1933:
1737:
1567:
1325:
558:
250:
97:
93:
77:
1424:
1407:
577:(1902–1965) and Joaquin Aguade Piñol (1918–1977), in 1954, and was named in 1956.
1691:
1009:
992:
3240:
2775:
2600:
2302:
1968:
1721:
573:
dermatologists who provided a brief description and explanation of the disease,
546:
541:
507:
499:
488:
350:
73:
993:"Erythema Nodosum, Mycobacterium avium Lymphadenitis, and a 15-mm Mantoux Test"
3062:
2735:
2576:
2453:
2171:
2143:
1913:
1702:
1608:
Der
Hautarzt; Zeitschrift fĂĽr Dermatologie, Venerologie, und Verwandte Gebiete
1544:
1060:
960:
Mandell, Douglas, and
Bennett's Principles and Practice of Infectious Diseases
877:
720:
537:
484:
228:
155:
1281:
1173:
1134:
958:
Renault, Cybèle A.; Ernst, Joel D. (2015). "Mycobacterium leprae (Leprosy)".
2867:
2780:
2730:
2494:
2081:
2053:
1958:
1793:
1732:
1661:
1594:
1341:"Erythema nodosum: Etiologic and predictive factors in a defined population"
503:
361:
159:
1575:
1517:
1509:
1474:
1433:
1366:
1317:
1142:
1118:
1076:
1018:
944:
885:
786:
736:
1191:
1103:
1045:
623:(in Spanish). Vol. 6 (3rd ed.). Barcelona: Salvat. p. 193.
3192:
3089:
2830:
2805:
2427:
2407:
2343:
2297:
2239:
2176:
2118:
1938:
1887:
1816:
1619:
1496:
Silverman, W. A. (2002). "The
Schizophrenic Career of a 'Monster Drug'".
925:
570:
279:
258:
1644:
1158:"Hepatitis B vaccine associated with erythema nodosum and polyarthritis"
2604:
2458:
2368:
2287:
2274:
2224:
2153:
1877:
1872:
1867:
1606:
MascarĂł, J. M. (1978). "In memoriam
Joaquin Piñol Aguadé, 1918--1977".
656:. GOSH NHS Foundation Trust. April 2012. Ref: 2012F1224. Archived from
440:
254:
118:
1466:
10.1002/1529-0131(200111)44:11<2686::AID-ART448>3.0.CO;2-H
2216:
2161:
1928:
1923:
1897:
1806:
1656:
468:
404:
1408:"A double-blind trial of depot corticosteroids in Behcet's syndrome"
1208:
Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon C. (2009).
185:
Erythema nodosum lesion in a person with light skin and tuberculosis
133:(rounded lumps) below the skin surface, usually on the shins. These
1358:
10.1002/1529-0131(200003)43:3<584::AID-ANR15>3.0.CO;2-6
209:
Several lesions of erythema nodosum in an individual with dark skin
1882:
495:
elevated, and the blood showing an increase in white blood cells.
52:
808:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
2463:
1982:
1801:
532:
can be used for persistent lesions whose cause remains unknown.
3244:
2834:
1753:
689:
Fitzpatrick's color atlas and synopsis of clinical dermatology
654:
Great Ormond Street Hospital for Children NHS Foundation Trust
129:
Erythema nodosum is characterised by 1–2-inch (25–51 mm)
836:
William D. James; Timothy G. Berger; Dirk M. Elston (2011).
1590:
Subacute Nodular Migratory Panniculitis (Vilanova Disease)
1449:"A double-blind trial of colchicine in Behçet's syndrome"
838:
Andrews' Diseases of the skin : clinical dermatology
249:
Several granulomatous mycobacterial infections including
246:
which, in children, is by far the most common precipitant
428:
EN may also be due to excessive antibody production in
1117:
Schwartz, Robert A.; Nervi, Stephen J. (2007-03-01).
682:
680:
678:
676:
674:
45:
Subacute migratory panniculitis of Vilanova and Piñol
1634:
840:(11th ed.). : Saunders/ Elsevier. p. 488.
691:(5th ed.). New York: McGraw-Hill. p. 148.
219:
EN is associated with a wide variety of conditions.
3507:
3453:
3444:
3392:
3288:
3279:
3190:
3152:
3097:
3088:
3061:
3010:
2901:
2885:
2866:
2749:
2716:
2660:
2645:
2636:
2593:
2564:
2543:
2534:
2487:
2446:
2415:
2404:
2397:
2386:
2331:
2273:
2215:
2152:
2072:
2001:
1990:
1981:
1896:
1860:
1792:
1785:
1712:
1638:
1266:(2nd ed.). Taylor & Francis. p. 151.
1061:"Cutaneous sarcoidosis: a dermatologic masquerader"
67:
40:
35:
1237:. Philadelphia: Hanley & Belfus. p. 105.
141:Less common variants of erythema nodosum include:
60:Erythema nodosum in a person who had recently had
1780:Diseases of the skin and appendages by morphology
1210:Robbins and Coltran Pathological Basis of Disease
831:
829:
340:Immune-mediated/Idiopathic granulomatous diseases
754:
752:
750:
748:
746:
549:in the treatment of erythema nodosum leprosum.
1531:Rouhi, Maureen (20 June 2005). "THALIDOMIDE".
1119:"Erythema nodosum: a sign of systemic disease"
759:Gilchrist, Heidi; Patterson, James W. (2010).
721:"Erythema nodosum: A sign of systemic disease"
714:
712:
710:
708:
3256:
2846:
2265:Pityriasis lichenoides et varioliformis acuta
1765:
8:
1919:Dermatofibroma (benign fibrous histiocytoma)
1260:"Practice Paper 4: Answers §Crohn's disease"
907:Laborada, Jennifer; Cohen, Philip R (2021).
557:Erythema nodosum is the most common form of
467:Erythema nodosum is diagnosed clinically. A
3405:Alpha-1 antitrypsin deficiency panniculitis
866:Scandinavian Journal of Infectious Diseases
650:"Information for Families Erythema nodosum"
3565:Reactive neutrophilic cutaneous conditions
3525:Marfanoid–progeroid–lipodystrophy syndrome
3450:
3285:
3263:
3249:
3241:
3144:Acute generalized exanthematous pustulosis
3094:
2907:
2882:
2853:
2839:
2831:
2642:
2540:
2412:
2401:
2394:
1998:
1987:
1789:
1772:
1758:
1750:
1635:
1203:
1201:
909:"Tuberculosis-Associated Erythema Nodosum"
859:
857:
51:
32:
3018:Acquired C1 esterase inhibitor deficiency
1464:
1423:
1356:
1181:
1092:Schweizerische Medizinische Wochenschrift
1032:Areias, E; GarcĂa E Silva, L (1984). "".
1008:
934:
924:
776:
27:Inflammation of fat tissue under the skin
3338:Subcutaneous fat necrosis of the newborn
1298:The American Journal of Gastroenterology
540:can be used in severe refractory cases.
372:Medications associated with EN include:
1560:Cochrane Database of Systematic Reviews
1533:Chemical & Engineering News Archive
1034:Medicina Cutanea Ibero-latino-americana
586:
239:Infections associated with EN include:
175:
170:subacute nodular migratory panniculitis
98:inflammation of subcutaneous fat tissue
18:Subacute nodular migratory panniculitis
2572:Disseminated intravascular coagulation
1264:Get Ahead! SURGERY 100 EMQs for Finals
719:Schwartz, R. A.; Nervi, S. J. (2007).
644:
642:
640:
3071:Episodic angioedema with eosinophilia
1212:. Saunders/Elsevier. pp. 372–3.
487:, intradermal tuberculin test, and a
7:
3515:Congenital generalized lipodystrophy
1385:The Lecturio Medical Concept Library
1258:Wigley, J.; Shantikumar, S. (2014).
997:Pediatric Infectious Disease Journal
3048:Urticaria-like follicular mucinosis
197:A single lesion of erythema nodosum
3570:Conditions of the subcutaneous fat
3464:Acquired generalized lipodystrophy
2354:Postinflammatory hyperpigmentation
968:10.1016/B978-1-4557-4801-3.00252-6
25:
2255:Transient acantholytic dermatosis
491:. The ESR is typically high, the
439:There is an association with the
3365:Lupus erythematosus panniculitis
2955:Localized heat contact urticaria
2932:Secondary cold contact urticaria
2364:Idiopathic guttate hypomelanosis
1310:10.1111/j.1572-0241.2006.00504.x
1156:Rogerson, S J; Nye, F J (1990).
778:10.1111/j.1529-8019.2010.01332.x
502:should be performed to rule out
202:
190:
178:
2374:Hypopigmented mycosis fungoides
1059:Katta, Rajani (15 April 2002).
687:Fitzpatrick, Thomas B. (2005).
3520:Familial partial lipodystrophy
3474:Acquired partial lipodystrophy
2927:Primary cold contact urticaria
2615:Lichen sclerosis et atrophicus
2323:Subcorneal pustular dermatosis
1949:Infantile digital fibromatosis
1568:10.1002/14651858.CD006949.pub2
481:antistreptolysin-O (ASO) titer
477:erythrocyte sedimentation rate
290:(LGV), caused by the bacteria
1:
3201:Necrolytic migratory erythema
3162:Erythema annulare centrifugum
3053:Chronic spontaneous urticaria
2207:Epidermolysis bullosa simplex
2044:Langerhans cell histiocytosis
227:About 30–50% of EN cases are
3484:HIV-associated lipodystrophy
3432:Superficial thrombophlebitis
2893:Urticarial allergic eruption
2683:Systemic lupus erythematosus
2438:Systemic lupus erythematosus
2129:Systemic lupus erythematosus
1010:10.1097/INF.0b013e31807a2fe1
619:Pedro-Pons, AgustĂn (1968).
407:associated with EN include:
329:associated with EN include:
3182:Annular erythema of infancy
1964:Lymphangioma circumscriptum
1425:10.1093/rheumatology/kei165
621:PatologĂa y ClĂnica MĂ©dicas
364:may be associated with EN.
96:condition characterized by
3591:
3127:Toxic epidermal necrolysis
2988:Delayed pressure urticaria
2786:Mucous membrane pemphigoid
1453:Arthritis & Rheumatism
1345:Arthritis & Rheumatism
145:Ulcerating forms, seen in
3479:Centrifugal lipodystrophy
3348:Post-steroid panniculitis
3226:Necrolytic acral erythema
3117:Erythema multiforme major
3112:Erythema multiforme minor
2968:
2945:
2910:
1545:10.1021/cen-v083n025.p122
1235:Infectious disease pearls
1123:American Family Physician
1065:American Family Physician
962:. pp. 2819–2831.e2.
878:10.1080/00365540410027184
810:Dermatology: 2-Volume Set
725:American Family Physician
432:leading to deposition of
62:streptococcal pharyngitis
59:
50:
3370:Sclerosing lipogranuloma
3122:Stevens–Johnson syndrome
2973:Dermatographic urticaria
2551:Thrombocytopenic purpura
2197:Dermatitis herpetiformis
2182:Acute contact dermatitis
2134:Pityriasis rubra pilaris
2059:Wiskott–Aldrich syndrome
2029:Lichen simplex chronicus
1909:Epidermal inclusion cyst
1233:Cunha, Burke A. (1999).
1174:10.1136/bmj.301.6747.345
506:diseases, in particular
287:Lymphogranuloma venereum
166:Erythema nodosum migrans
3499:Localized lipodystrophy
3360:Weber–Christian disease
3177:Erythema gyratum repens
2816:Squamous-cell carcinoma
2811:Systemic histoplasmosis
2202:Porphyria cutanea tarda
1832:Squamous-cell carcinoma
395:Hepatitis B vaccination
244:Streptococcal infection
231:(of an unknown cause).
154:, when a subcutaneous
3489:Lipoatrophia annularis
3304:Cytophagic histiocytic
2861:Urticaria and erythema
2791:Cicatricial pemphigoid
2708:Acne keloidalis nuchae
2703:Folliculitis decalvans
1510:10.1542/peds.110.2.404
599:Johns Hopkins Medicine
575:Xavier Montiu Vilanova
412:Non-Hodgkin's lymphoma
273:Histoplasma capsulatum
3076:Hereditary angioedema
2993:Cholinergic urticaria
2937:Reflex cold urticaria
2693:Loose anagen syndrome
2620:Necrobiosis lipoidica
2556:Actinic/solar purpura
2230:Insect bite reactions
2019:Seborrheic dermatitis
1842:Merkel-cell carcinoma
1822:Molluscum contagiosum
293:Chlamydia trachomatis
266:Mycoplasma pneumoniae
152:Erythema contusiforme
3355:Lipodermatosclerosis
3333:needle-shaped clefts
3221:Generalized erythema
3028:Autoimmune urticaria
3023:Adrenergic urticaria
2978:Vibratory angioedema
2516:Annulare centrifugum
2039:Glucagonoma syndrome
1837:Basal-cell carcinoma
1812:Seborrheic keratosis
926:10.7759/cureus.20184
812:. St. Louis: Mosby.
765:Dermatologic Therapy
483:and throat culture,
327:Autoimmune disorders
305:Coccidioides immitis
3555:Autoimmune diseases
3402:without vasculitis:
3343:Sclerema neonatorum
3295:without vasculitis
3167:Erythema marginatum
3099:Erythema multiforme
3043:Schnitzler syndrome
2998:Aquagenic urticaria
2761:Aphthous stomatitis
2698:Lichen planopilaris
2673:Androgenic alopecia
2479:Fixed drug eruption
2054:Pemphigus foliaceus
1954:Granular cell tumor
430:lepromatous leprosy
385:Oral contraceptives
316:Cat scratch disease
3384:Erythema induratum
3380:Nodular vasculitis
3038:Galvanic urticaria
3033:Exercise urticaria
2983:Pressure urticaria
2903:Physical urticaria
2886:Allergic urticaria
2781:Pemphigus vulgaris
2610:Granuloma annulare
2474:Carcinoid syndrome
2359:Tuberous sclerosis
2318:Coccidioidomycosis
2192:Bullous pemphigoid
2187:Pemphigus vulgaris
2119:Secondary syphilis
2009:Contact dermatitis
1713:External resources
1381:"Erythema Nodosum"
1098:(27–28): 1168–76.
595:"Erythema Nodosum"
493:C-reactive protein
299:Epstein-Barr virus
113:Pre-eruptive phase
108:Signs and symptoms
3575:Medical mnemonics
3542:
3541:
3538:
3537:
3440:
3439:
3238:
3237:
3234:
3233:
3154:Figurate erythema
3084:
3083:
3006:
3005:
2828:
2827:
2824:
2823:
2668:Telogen effluvium
2632:
2631:
2628:
2627:
2589:
2588:
2585:
2584:
2530:
2529:
2382:
2381:
2250:Lichen spinulosus
2245:Keratosis pilaris
2124:Mycosis fungoides
2024:Stasis dermatitis
2014:Atopic dermatitis
1977:
1976:
1852:Trichoepithelioma
1827:Actinic keratosis
1747:
1746:
1244:978-1-56053-203-3
1219:978-1-4160-4930-2
977:978-1-4557-4801-3
847:978-1-4377-0314-6
819:978-1-4160-2999-1
698:978-0-07-144019-6
630:978-84-345-1106-4
423:Pancreatic cancer
418:Carcinoid tumours
83:
82:
30:Medical condition
16:(Redirected from
3582:
3451:
3429:with vasculitis:
3410:Erythema nodosum
3377:with vasculitis:
3286:
3273:subcutaneous fat
3265:
3258:
3251:
3242:
3206:Erythema toxicum
3172:Erythema migrans
3138:Erythema nodosum
3095:
2908:
2883:
2855:
2848:
2841:
2832:
2766:Oral candidiasis
2643:
2541:
2469:Erythema nodosum
2413:
2402:
2395:
2339:Tinea versicolor
2177:Bullous impetigo
2114:Pityriasis rosea
2049:Lichen sclerosus
2034:Darier's disease
1999:
1988:
1944:Kaposi's sarcoma
1790:
1774:
1767:
1760:
1751:
1636:
1624:
1623:
1603:
1597:
1586:
1580:
1579:
1555:
1549:
1548:
1528:
1522:
1521:
1493:
1487:
1486:
1468:
1444:
1438:
1437:
1427:
1403:
1397:
1396:
1394:
1392:
1377:
1371:
1370:
1360:
1336:
1330:
1329:
1292:
1286:
1285:
1255:
1249:
1248:
1230:
1224:
1223:
1205:
1196:
1195:
1185:
1153:
1147:
1146:
1114:
1108:
1107:
1087:
1081:
1080:
1071:(8): 1581–1584.
1056:
1050:
1049:
1029:
1023:
1022:
1012:
988:
982:
981:
955:
949:
948:
938:
928:
904:
898:
897:
861:
852:
851:
833:
824:
823:
805:
799:
798:
780:
756:
741:
740:
716:
703:
702:
684:
669:
668:
666:
665:
646:
635:
634:
616:
610:
609:
607:
605:
591:
530:Potassium iodide
512:Löfgren syndrome
434:immune complexes
334:Behçet's disease
206:
194:
182:
86:Erythema nodosum
55:
36:Erythema nodosum
33:
21:
3590:
3589:
3585:
3584:
3583:
3581:
3580:
3579:
3545:
3544:
3543:
3534:
3530:Poland syndrome
3503:
3436:
3388:
3275:
3269:
3239:
3230:
3216:Palmar erythema
3186:
3148:
3102:
3080:
3057:
3011:Other urticaria
3002:
2964:
2960:Solar urticaria
2941:
2897:
2870:
2862:
2859:
2829:
2820:
2752:
2745:
2712:
2678:Alopecia areata
2656:
2638:
2624:
2581:
2560:
2536:
2526:
2483:
2442:
2428:Viral exanthems
2406:
2390:
2388:
2378:
2349:Pityriasis alba
2327:
2269:
2211:
2148:
2068:
2064:Zinc deficiency
1994:
1992:
1973:
1901:
1892:
1856:
1847:Nevus sebaceous
1781:
1778:
1748:
1743:
1742:
1708:
1707:
1647:
1633:
1628:
1627:
1605:
1604:
1600:
1587:
1583:
1562:(3): CD006949.
1557:
1556:
1552:
1530:
1529:
1525:
1495:
1494:
1490:
1459:(11): 2686–92.
1446:
1445:
1441:
1405:
1404:
1400:
1390:
1388:
1379:
1378:
1374:
1338:
1337:
1333:
1294:
1293:
1289:
1274:
1257:
1256:
1252:
1245:
1232:
1231:
1227:
1220:
1207:
1206:
1199:
1155:
1154:
1150:
1116:
1115:
1111:
1089:
1088:
1084:
1058:
1057:
1053:
1031:
1030:
1026:
990:
989:
985:
978:
957:
956:
952:
906:
905:
901:
863:
862:
855:
848:
835:
834:
827:
820:
807:
806:
802:
758:
757:
744:
718:
717:
706:
699:
686:
685:
672:
663:
661:
648:
647:
638:
631:
618:
617:
613:
603:
601:
593:
592:
588:
583:
567:
555:
534:Corticosteroids
520:
465:
456:
454:Pathophysiology
402:
370:
359:
346:Crohn's disease
342:
324:
237:
225:
217:
210:
207:
198:
195:
186:
183:
168:(also known as
147:Crohn's disease
127:
115:
110:
31:
28:
23:
22:
15:
12:
11:
5:
3588:
3586:
3578:
3577:
3572:
3567:
3562:
3557:
3547:
3546:
3540:
3539:
3536:
3535:
3533:
3532:
3527:
3522:
3517:
3511:
3509:
3505:
3504:
3502:
3501:
3492:
3491:
3486:
3481:
3476:
3467:
3466:
3457:
3455:
3448:
3442:
3441:
3438:
3437:
3435:
3434:
3425:
3424:
3423:
3422:
3417:
3407:
3398:
3396:
3390:
3389:
3387:
3386:
3373:
3372:
3367:
3362:
3357:
3352:
3351:
3350:
3345:
3340:
3329:
3328:
3327:
3326:
3321:
3316:
3311:
3306:
3301:
3292:
3290:
3283:
3277:
3276:
3270:
3268:
3267:
3260:
3253:
3245:
3236:
3235:
3232:
3231:
3229:
3228:
3223:
3218:
3213:
3208:
3203:
3197:
3195:
3188:
3187:
3185:
3184:
3179:
3174:
3169:
3164:
3158:
3156:
3150:
3149:
3147:
3146:
3141:
3129:
3124:
3119:
3114:
3108:
3106:
3092:
3086:
3085:
3082:
3081:
3079:
3078:
3073:
3067:
3065:
3059:
3058:
3056:
3055:
3050:
3045:
3040:
3035:
3030:
3025:
3020:
3014:
3012:
3008:
3007:
3004:
3003:
3001:
3000:
2995:
2990:
2985:
2980:
2975:
2969:
2966:
2965:
2963:
2962:
2957:
2952:
2950:Heat urticaria
2946:
2943:
2942:
2940:
2939:
2934:
2929:
2924:
2923:
2922:
2915:Cold urticaria
2911:
2905:
2899:
2898:
2896:
2895:
2889:
2887:
2880:
2864:
2863:
2860:
2858:
2857:
2850:
2843:
2835:
2826:
2825:
2822:
2821:
2819:
2818:
2813:
2808:
2803:
2801:Coxsackievirus
2798:
2793:
2788:
2783:
2778:
2773:
2768:
2763:
2757:
2755:
2747:
2746:
2744:
2743:
2738:
2733:
2728:
2722:
2720:
2714:
2713:
2711:
2710:
2705:
2700:
2695:
2690:
2685:
2680:
2675:
2670:
2664:
2662:
2658:
2657:
2655:
2654:
2651:
2649:
2640:
2634:
2633:
2630:
2629:
2626:
2625:
2623:
2622:
2617:
2612:
2607:
2597:
2595:
2591:
2590:
2587:
2586:
2583:
2582:
2580:
2579:
2574:
2568:
2566:
2562:
2561:
2559:
2558:
2553:
2547:
2545:
2538:
2532:
2531:
2528:
2527:
2525:
2524:
2518:
2513:
2511:Gyratum repens
2508:
2503:
2497:
2491:
2489:
2485:
2484:
2482:
2481:
2476:
2471:
2466:
2461:
2456:
2450:
2448:
2444:
2443:
2441:
2440:
2435:
2433:Toxic erythema
2430:
2425:
2423:Drug eruptions
2419:
2417:
2410:
2399:
2392:
2384:
2383:
2380:
2379:
2377:
2376:
2371:
2366:
2361:
2356:
2351:
2346:
2341:
2335:
2333:
2329:
2328:
2326:
2325:
2320:
2315:
2310:
2305:
2300:
2295:
2290:
2285:
2279:
2277:
2271:
2270:
2268:
2267:
2262:
2260:Lichen nitidus
2257:
2252:
2247:
2242:
2237:
2232:
2227:
2221:
2219:
2213:
2212:
2210:
2209:
2204:
2199:
2194:
2189:
2184:
2179:
2174:
2169:
2164:
2162:Herpes simplex
2158:
2156:
2150:
2149:
2147:
2146:
2141:
2136:
2131:
2126:
2121:
2116:
2111:
2105:
2100:
2095:
2090:
2084:
2078:
2076:
2070:
2069:
2067:
2066:
2061:
2056:
2051:
2046:
2041:
2036:
2031:
2026:
2021:
2016:
2011:
2005:
2003:
1996:
1985:
1979:
1978:
1975:
1974:
1972:
1971:
1966:
1961:
1956:
1951:
1946:
1941:
1936:
1931:
1926:
1921:
1916:
1911:
1905:
1903:
1894:
1893:
1891:
1890:
1885:
1880:
1875:
1870:
1864:
1862:
1858:
1857:
1855:
1854:
1849:
1844:
1839:
1834:
1829:
1824:
1819:
1814:
1809:
1804:
1798:
1796:
1787:
1783:
1782:
1779:
1777:
1776:
1769:
1762:
1754:
1745:
1744:
1741:
1740:
1729:
1717:
1716:
1714:
1710:
1709:
1706:
1705:
1694:
1683:
1664:
1648:
1643:
1642:
1640:
1639:Classification
1632:
1631:External links
1629:
1626:
1625:
1598:
1581:
1550:
1523:
1488:
1439:
1398:
1387:. 24 July 2020
1372:
1331:
1304:(5): 1012–23.
1287:
1272:
1250:
1243:
1225:
1218:
1197:
1148:
1129:(5): 695–700.
1109:
1082:
1051:
1024:
1003:(8): 764–765.
983:
976:
950:
919:(12): e20184.
899:
872:(6–7): 424–7.
853:
846:
825:
818:
800:
742:
731:(5): 695–700.
704:
697:
670:
636:
629:
611:
585:
584:
582:
579:
566:
563:
554:
551:
519:
516:
464:
461:
455:
452:
426:
425:
420:
415:
401:
398:
397:
396:
393:
390:
387:
382:
377:
369:
366:
358:
355:
354:
353:
348:
341:
338:
337:
336:
323:
320:
319:
318:
313:
301:
296:
283:
276:
269:
262:
247:
236:
233:
224:
221:
216:
213:
212:
211:
208:
201:
199:
196:
189:
187:
184:
177:
174:
173:
163:
149:
126:
125:Eruptive phase
123:
114:
111:
109:
106:
81:
80:
71:
65:
64:
57:
56:
48:
47:
42:
38:
37:
29:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3587:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3552:
3550:
3531:
3528:
3526:
3523:
3521:
3518:
3516:
3513:
3512:
3510:
3506:
3500:
3497:
3494:
3493:
3490:
3487:
3485:
3482:
3480:
3477:
3475:
3472:
3469:
3468:
3465:
3462:
3459:
3458:
3456:
3452:
3449:
3447:
3446:Lipodystrophy
3443:
3433:
3430:
3427:
3426:
3421:
3418:
3416:
3413:
3412:
3411:
3408:
3406:
3403:
3400:
3399:
3397:
3395:
3391:
3385:
3381:
3378:
3375:
3374:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3349:
3346:
3344:
3341:
3339:
3336:
3335:
3334:
3331:
3330:
3325:
3322:
3320:
3317:
3315:
3312:
3310:
3307:
3305:
3302:
3300:
3297:
3296:
3294:
3293:
3291:
3287:
3284:
3282:
3278:
3274:
3271:Disorders of
3266:
3261:
3259:
3254:
3252:
3247:
3246:
3243:
3227:
3224:
3222:
3219:
3217:
3214:
3212:
3209:
3207:
3204:
3202:
3199:
3198:
3196:
3194:
3189:
3183:
3180:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3159:
3157:
3155:
3151:
3145:
3142:
3139:
3135:
3134:
3130:
3128:
3125:
3123:
3120:
3118:
3115:
3113:
3110:
3109:
3107:
3105:
3104:drug eruption
3100:
3096:
3093:
3091:
3087:
3077:
3074:
3072:
3069:
3068:
3066:
3064:
3060:
3054:
3051:
3049:
3046:
3044:
3041:
3039:
3036:
3034:
3031:
3029:
3026:
3024:
3021:
3019:
3016:
3015:
3013:
3009:
2999:
2996:
2994:
2991:
2989:
2986:
2984:
2981:
2979:
2976:
2974:
2971:
2970:
2967:
2961:
2958:
2956:
2953:
2951:
2948:
2947:
2944:
2938:
2935:
2933:
2930:
2928:
2925:
2921:
2918:
2917:
2916:
2913:
2912:
2909:
2906:
2904:
2900:
2894:
2891:
2890:
2888:
2884:
2881:
2878:
2874:
2869:
2865:
2856:
2851:
2849:
2844:
2842:
2837:
2836:
2833:
2817:
2814:
2812:
2809:
2807:
2804:
2802:
2799:
2797:
2794:
2792:
2789:
2787:
2784:
2782:
2779:
2777:
2774:
2772:
2771:Lichen planus
2769:
2767:
2764:
2762:
2759:
2758:
2756:
2754:
2748:
2742:
2739:
2737:
2734:
2732:
2729:
2727:
2726:Onychomycosis
2724:
2723:
2721:
2719:
2715:
2709:
2706:
2704:
2701:
2699:
2696:
2694:
2691:
2689:
2688:Tinea capitis
2686:
2684:
2681:
2679:
2676:
2674:
2671:
2669:
2666:
2665:
2663:
2659:
2653:
2652:
2650:
2648:
2644:
2641:
2637:Miscellaneous
2635:
2621:
2618:
2616:
2613:
2611:
2608:
2606:
2602:
2599:
2598:
2596:
2592:
2578:
2575:
2573:
2570:
2569:
2567:
2563:
2557:
2554:
2552:
2549:
2548:
2546:
2542:
2539:
2535:Nonblanchable
2533:
2522:
2519:
2517:
2514:
2512:
2509:
2507:
2504:
2502:
2498:
2496:
2493:
2492:
2490:
2486:
2480:
2477:
2475:
2472:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2451:
2449:
2445:
2439:
2436:
2434:
2431:
2429:
2426:
2424:
2421:
2420:
2418:
2414:
2411:
2409:
2403:
2400:
2396:
2393:
2385:
2375:
2372:
2370:
2367:
2365:
2362:
2360:
2357:
2355:
2352:
2350:
2347:
2345:
2342:
2340:
2337:
2336:
2334:
2332:Hypopigmented
2330:
2324:
2321:
2319:
2316:
2314:
2311:
2309:
2306:
2304:
2301:
2299:
2296:
2294:
2291:
2289:
2286:
2284:
2283:Acne vulgaris
2281:
2280:
2278:
2276:
2272:
2266:
2263:
2261:
2258:
2256:
2253:
2251:
2248:
2246:
2243:
2241:
2238:
2236:
2235:Lichen planus
2233:
2231:
2228:
2226:
2223:
2222:
2220:
2218:
2214:
2208:
2205:
2203:
2200:
2198:
2195:
2193:
2190:
2188:
2185:
2183:
2180:
2178:
2175:
2173:
2170:
2168:
2167:Herpes zoster
2165:
2163:
2160:
2159:
2157:
2155:
2151:
2145:
2142:
2140:
2139:Parapsoriasis
2137:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2112:
2109:
2106:
2104:
2101:
2099:
2096:
2094:
2091:
2089:
2085:
2083:
2080:
2079:
2077:
2075:
2071:
2065:
2062:
2060:
2057:
2055:
2052:
2050:
2047:
2045:
2042:
2040:
2037:
2035:
2032:
2030:
2027:
2025:
2022:
2020:
2017:
2015:
2012:
2010:
2007:
2006:
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1967:
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1962:
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1957:
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1945:
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1932:
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1927:
1925:
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1917:
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1654:
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1646:
1641:
1637:
1630:
1621:
1617:
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1351:(3): 584–92.
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1083:
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1043:
1040:(6): 489–95.
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660:on 2017-04-19
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72:
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66:
63:
58:
54:
49:
46:
43:
39:
34:
19:
3495:
3470:
3461:generalized:
3460:
3428:
3409:
3401:
3376:
3332:
3281:Panniculitis
3211:Erythroderma
3137:
3133:panniculitis
3131:
2741:Ingrown nail
2468:
2313:Dermatophyte
2308:Gonococcemia
2293:Folliculitis
1934:Neurofibroma
1902:subcutaneous
1731:
1720:
1696:
1685:
1666:
1651:
1611:
1607:
1601:
1588:
1584:
1559:
1553:
1536:
1532:
1526:
1504:(2): 404–6.
1501:
1497:
1491:
1456:
1452:
1442:
1415:
1412:Rheumatology
1411:
1401:
1389:. Retrieved
1384:
1375:
1348:
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1301:
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1234:
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996:
986:
959:
953:
916:
912:
902:
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865:
837:
809:
803:
771:(4): 320–7.
768:
764:
728:
724:
688:
662:. Retrieved
658:the original
653:
620:
614:
602:. Retrieved
598:
589:
568:
559:panniculitis
556:
553:Epidemiology
528:
521:
497:
474:
466:
457:
445:
438:
427:
403:
380:Sulfonamides
371:
360:
325:
310:Valley fever
303:
291:
285:
278:
271:
264:
251:tuberculosis
238:
226:
218:
169:
165:
151:
140:
135:subcutaneous
128:
116:
94:inflammatory
89:
85:
84:
78:rheumatology
44:
2796:Herpesvirus
2776:Leukoplakia
2601:Scleroderma
2488:Specialized
2416:Generalized
2391:involvement
2303:Candidiasis
1995:involvement
1969:Myxoid cyst
1817:Acrochordon
1722:MedlinePlus
1539:(25): 122.
547:clofazimine
542:Thalidomide
508:sarcoidosis
500:chest X-ray
489:chest x-ray
389:Penicillins
368:Medications
351:Sarcoidosis
74:Dermatology
41:Other names
3549:Categories
3508:Congenital
3496:localized:
3319:Pancreatic
3063:Angioedema
2736:Paronychia
2577:Vasculitis
2501:Multiforme
2499:Erythema (
2454:Cellulitis
2405:Blanchable
2154:Blistering
2144:Ichthyosis
2002:Eczematous
1914:Hemangioma
1698:DiseasesDB
1498:Pediatrics
664:2017-04-19
581:References
538:colchicine
485:urinalysis
376:Omeprazole
322:Autoimmune
229:idiopathic
223:Idiopathic
156:hemorrhage
102:idiopathic
3560:Erythemas
3324:Traumatic
3309:Factitial
2868:Urticaria
2731:Psoriasis
2639:disorders
2594:Indurated
2495:Urticaria
2447:Localized
2389:epidermal
2172:Varicella
2082:Psoriasis
1993:epidermal
1959:Leiomyoma
1861:Pigmented
1794:Epidermal
1733:eMedicine
1595:eMedicine
1282:893164082
1135:0002-838X
518:Treatment
504:pulmonary
463:Diagnosis
446:A useful
362:Pregnancy
357:Pregnancy
235:Infection
160:contusion
69:Specialty
3471:partial:
3454:Acquired
3193:erythema
3090:Erythema
2920:Familial
2806:Syphilis
2753:membrane
2408:Erythema
2344:Vitiligo
2298:Impetigo
2275:Pustular
2240:Miliaria
2088:Corporis
1939:Xanthoma
1888:Melanoma
1868:Freckles
1738:derm/138
1576:19588412
1518:12165600
1483:19523919
1475:11710724
1434:16263779
1367:10728752
1318:16696785
1143:17375516
1077:11989634
1019:17848899
945:35004007
894:13123205
886:15307561
795:39695627
787:20666819
737:17375516
448:mnemonic
392:Bromides
280:Yersinia
259:M. avium
162:(bruise)
92:) is an
3420:Chronic
3289:Lobular
2877:chronic
2605:morphea
2565:Papular
2544:Macular
2537:Purpura
2521:Ab igne
2506:Migrans
2459:Abscess
2387:Without
2369:Leprosy
2288:Rosacea
2225:Scabies
2217:Papular
2086:Tinea (
2074:Scaling
1878:Melasma
1873:Lentigo
1786:Growths
1692:D004893
1391:21 July
1326:7720460
1192:2144199
1183:1663612
1104:9324739
1046:6152299
936:8723782
604:12 June
571:Catalan
479:(ESR),
441:HLA-B27
405:Cancers
261:complex
255:leprosy
131:nodules
119:malaise
3394:Septal
3191:Other
2751:Mucous
2647:Ulcers
2108:Faciei
2103:Manuum
2093:Cruris
1983:Rashes
1929:Lipoma
1924:Keloid
1898:Dermal
1807:Callus
1727:000881
1620:363649
1618:
1574:
1516:
1481:
1473:
1432:
1365:
1324:
1316:
1280:
1270:
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1190:
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933:
913:Cureus
892:
884:
844:
816:
793:
785:
735:
695:
627:
565:Eponym
469:biopsy
400:Cancer
257:, and
215:Causes
3415:Acute
3314:Gouty
2873:acute
2098:Pedis
1883:Nevus
1681:017.1
1677:695.2
1479:S2CID
1322:S2CID
890:S2CID
791:S2CID
414:(NHL)
3299:Cold
2718:Nail
2661:Hair
2464:Boil
1991:With
1802:Wart
1703:4462
1687:MeSH
1672:9-CM
1616:PMID
1572:PMID
1514:PMID
1471:PMID
1430:PMID
1393:2021
1363:PMID
1314:PMID
1278:OCLC
1268:ISBN
1239:ISBN
1214:ISBN
1188:PMID
1139:PMID
1131:ISSN
1100:PMID
1073:PMID
1042:PMID
1015:PMID
972:ISBN
941:PMID
882:PMID
842:ISBN
814:ISBN
783:PMID
733:PMID
693:ISBN
625:ISBN
606:2019
536:and
510:and
2398:Red
1900:and
1668:ICD
1662:L52
1653:ICD
1593:at
1564:doi
1541:doi
1506:doi
1502:110
1461:doi
1420:doi
1353:doi
1306:doi
1302:101
1178:PMC
1170:doi
1166:301
1162:BMJ
1096:127
1005:doi
964:doi
931:PMC
921:doi
874:doi
773:doi
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