Knowledge

Surfactant protein D

Source πŸ“

398: 375: 2845: 2875: 2860: 2890: 2830: 272: 297: 2815: 2800: 2785: 649: 404: 303: 29: 2770: 2918: 55: 2844: 2874: 2859: 2889: 2829: 2364:
Rust K, Bingle L, Mariencheck W, Persson A, Crouch EC (February 1996). "Characterization of the human surfactant protein D promoter: transcriptional regulation of SP-D gene expression by glucocorticoids".
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KΓΆlble K, Lu J, Mole SE, Kaluz S, Reid KB (August 1993). "Assignment of the human pulmonary surfactant protein D gene (SFTP4) to 10q22-q23 close to the surfactant protein A gene cluster".
2133:
Rust K, Grosso L, Zhang V, Chang D, Persson A, Longmore W, et al. (October 1991). "Human surfactant protein D: SP-D contains a C-type lectin carbohydrate recognition domain".
1433:
Rust K, Grosso L, Zhang V, Chang D, Persson A, Longmore W, et al. (October 1991). "Human surfactant protein D: SP-D contains a C-type lectin carbohydrate recognition domain".
2784: 411: 310: 1241:, a nucleating neck region, and a C-terminal lectin domain. Three of these subunits assemble to form a homotrimer, which further assemble into a tetrameric complex. 2431:"Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule" 1672:"Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule" 1627:
Tino MJ, Wright JR (April 1999). "Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner".
2069:
Persson AV, Gibbons BJ, Shoemaker JD, Moxley MA, Longmore WJ (December 1992). "The major glycolipid recognized by SP-D in surfactant is phosphatidylinositol".
2162:
Kuroki Y, Shiratori M, Ogasawara Y, Tsuzuki A, Akino T (November 1991). "Characterization of pulmonary surfactant protein D: its copurification with lipids".
952: 933: 233: 2853:: Crystal structure of the trimer neck and carbohydrate recognition domain of human surfactant protein D in complex with p-nitrophenyl maltoside 2959: 2883:: crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with inositol-1-phosphate 2868:: crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with N-acetyl mannosamine 2978: 2749: 1353: 1335: 1915:"Selective inhibition of inducible NO synthase activity in vivo reverses inflammatory abnormalities in surfactant protein D-deficient mice" 397: 2228:"A different combination of transcription factors modulates the expression of the human transferrin promoter in liver and Sertoli cells" 2898:: crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with myoinositol 2838:: crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with maltotriose 1152: 1159: 374: 2769: 1517: 1713:"Molecular mechanisms of inhibition of influenza by surfactant protein D revealed by large-scale molecular dynamics simulation" 1322: 1301: 2519:"Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D" 296: 271: 2607:"Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D" 1318: 52: 1297: 213: 1250: 2823:: High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D with maltose 410: 309: 2952: 403: 302: 2742: 1258: 2721: 997: 221: 978: 2988: 2466:"Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D" 1378:"A parallel three stranded alpha-helical bundle at the nucleation site of collagen triple-helix formation" 1862:"Segmental allergen challenge alters multimeric structure and function of surfactant protein D in humans" 2945: 2808:: High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D 1531:
Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME (May 2008).
285: 2331:"Genomic organization of human surfactant protein D (SP-D). SP-D is encoded on chromosome 10q22.2-23.1" 2735: 2565: 2477: 2001:
Hansen S, Holmskov U (August 1998). "Structural aspects of collectins and receptors for collectins".
1956:
Guo CJ, Atochina-Vasserman EN, Abramova E, Foley JP, Zaman A, Crouch E, et al. (November 2008).
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Atochina-Vasserman EN, Winkler C, Abramova H, Schaumann F, Krug N, Gow AJ, et al. (April 2011).
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Guo CJ, Atochina-Vasserman EN, Abramova E, Foley JP, Zaman A, Crouch E, et al. (November 2008).
1389: 1274: 1234: 1219: 200: 1813:"Surfactant dysfunction and lung inflammation in the female mouse model of lymphangioleiomyomatosis" 2983: 2552:
Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, et al. (September 1999).
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Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, et al. (November 2013).
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Atochina-Vasserman EN, Beers MF, Kadire H, Tomer Y, Inch A, Scott P, et al. (December 2007).
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Atochina-Vasserman EN, Guo CJ, Abramova E, Golden TN, Sims M, James ML, et al. (July 2015).
1652: 1415: 245: 2717: 2677:"Activity of pulmonary surfactant protein-D (SP-D) in vivo is dependent on oligomeric structure" 1135: 1114: 1088: 1067: 2605:
Lausen M, Lynch N, Schlosser A, Tornoe I, Saekmose SG, Teisner B, et al. (November 1999).
2698: 2663: 2628: 2593: 2540: 2505: 2452: 2417: 2382: 2352: 2313: 2278: 2249: 2214: 2179: 2150: 2121: 2086: 2057: 2018: 1989: 1944: 1891: 1842: 1793: 1742: 1693: 1644: 1609: 1562: 1499: 1450: 1407: 1262: 193: 45: 2688: 2653: 2618: 2583: 2573: 2530: 2495: 2485: 2442: 2407: 2374: 2342: 2303: 2270: 2239: 2204: 2171: 2142: 2111: 2078: 2047: 2039: 2010: 1979: 1969: 1934: 1926: 1881: 1873: 1832: 1824: 1783: 1773: 1732: 1724: 1683: 1636: 1599: 1552: 1544: 1489: 1481: 1442: 1397: 490: 421: 365: 320: 2793:: Solution Structure of the Coiled-Coil Trimerization Domain from Lung Surfactant Protein D 648: 241: 465: 2464:
Botas C, Poulain F, Akiyama J, Brown C, Allen L, Goerke J, et al. (September 1998).
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Holmskov U, Lawson P, Teisner B, Tornoe I, Willis AC, Morgan C, et al. (May 1997).
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Holmskov U, Lawson P, Teisner B, Tornoe I, Willis AC, Morgan C, et al. (May 1997).
1393: 2929: 2308: 2291: 2052: 2031: 1984: 1957: 1939: 1914: 1886: 1861: 1837: 1812: 1788: 1761: 1737: 1712: 1557: 1532: 1494: 1469: 1265:. Post-translational modification of SP-D i.e. S-nitrosylation switches its function. 28: 2535: 2518: 2347: 2330: 2244: 2227: 2209: 2192: 2116: 2099: 2014: 1604: 1587: 867: 862: 857: 852: 847: 842: 837: 832: 827: 822: 817: 812: 807: 802: 797: 792: 787: 771: 766: 761: 756: 751: 746: 741: 736: 731: 726: 710: 705: 700: 695: 690: 2972: 2588: 2553: 2500: 2465: 2175: 2146: 1446: 1402: 1377: 677: 2032:"Purification, characterization and cDNA cloning of human lung surfactant protein D" 1656: 1470:"Purification, characterization and cDNA cloning of human lung surfactant protein D" 1583: 1419: 483: 262: 225: 2658: 2641: 1974: 1930: 1778: 249: 2642:"Localization of lung surfactant protein D on mucosal surfaces in human tissues" 2378: 1533:"Surfactant protein D alters allergic lung responses in mice and human subjects" 1358:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
1877: 1548: 566: 2554:"Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D" 2292:"Accumulation of surfactant protein D in human pulmonary alveolar proteinosis" 382: 279: 229: 2623: 2606: 2578: 2490: 2447: 2430: 1828: 1688: 1671: 1640: 2396:"Normalization and subtraction: two approaches to facilitate gene discovery" 1223: 897: 626: 504: 449: 436: 348: 335: 237: 2702: 2693: 2676: 2667: 2632: 2597: 2544: 2274: 2100:"Pulmonary surfactant protein D specifically binds to phosphatidylinositol" 1993: 1948: 1895: 1846: 1797: 1746: 1648: 1566: 2509: 2456: 2421: 2386: 2356: 2317: 2282: 2253: 2218: 2183: 2154: 2125: 2090: 2061: 2022: 1697: 1613: 1503: 1454: 1411: 1199: 1194: 1238: 1183: 1042: 1023: 2082: 1958:"S-nitrosylation of surfactant protein-D controls inflammatory function" 1762:"S-nitrosylation of surfactant protein-D controls inflammatory function" 2925: 2640:
Madsen J, Kliem A, Tornoe I, Skjodt K, Koch C, Holmskov U (June 2000).
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Zhang L, Ikegami M, Crouch EC, Korfhagen TR, Whitsett JA (June 2001).
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
882: 878: 1230: 217: 2731: 1518:"Entrez Gene: SFTPD surfactant, pulmonary-associated protein D" 657: 2727: 2193:"Molecular structure of pulmonary surfactant protein D (SP-D)" 1588:"Molecular structure of pulmonary surfactant protein D (SP-D)" 1237:. Each SP-D subunit is composed of an N-terminal domain, a 2367:
American Journal of Respiratory Cell and Molecular Biology
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Schaeffer E, Guillou F, Part D, Zakin MM (November 1993).
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American Journal of Respiratory and Critical Care Medicine
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American Journal of Respiratory Cell and Molecular Biology
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American Journal of Respiratory Cell and Molecular Biology
863:
regulation of adhesion of symbiont to host epithelial cell
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HΓ₯kansson K, Lim NK, Hoppe HJ, Reid KB (March 1999).
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Crouch E, Persson A, Chang D, Heuser J (June 1994).
1128: 1107: 1081: 1060: 2394:Bonaldo MF, Lennon G, Soares MB (September 1996). 1314: 1312: 1310: 1293: 1291: 1289: 808:respiratory gaseous exchange by respiratory system 204:, COLEC7, PSP-D, SFTP4, SP-D, surfactant protein D 1222:part of the collagenous family of lectins called 420: 319: 2098:Ogasawara Y, Kuroki Y, Akino T (October 1992). 16:Protein-coding gene in the species Homo sapiens 1578: 1576: 1537:The Journal of Allergy and Clinical Immunology 1319:GRCm38: Ensembl release 89: ENSMUSG00000021795 2953: 2778:: LUNG SURFACTANT PROTEIN D (SP-D) (FRAGMENT) 2743: 2290:Crouch E, Persson A, Chang D (January 1993). 8: 1586:, Persson A, Chang D, Heuser J (June 1994). 1371: 1369: 1367: 1298:GRCh38: Ensembl release 89: ENSG00000133661 823:negative regulation of T cell proliferation 2960: 2946: 2750: 2736: 2728: 893: 673: 461: 360: 257: 63: 2720:at the U.S. National Library of Medicine 2692: 2657: 2622: 2587: 2577: 2534: 2499: 2489: 2446: 2411: 2346: 2307: 2243: 2208: 2115: 2051: 1983: 1973: 1938: 1885: 1836: 1787: 1777: 1736: 1687: 1603: 1556: 1493: 1401: 1376:Hoppe HJ, Barlow PN, Reid KB (May 1994). 813:reactive oxygen species metabolic process 2765: 2135:Archives of Biochemistry and Biophysics 1435:Archives of Biochemistry and Biophysics 1285: 1249:Surfactant protein D has been shown to 2030:Lu J, Willis AC, Reid KB (June 1992). 1468:Lu J, Willis AC, Reid KB (June 1992). 18: 425: 386: 381: 324: 283: 278: 7: 2914: 2912: 1226:. In humans, SP-D is encoded by the 858:induction of bacterial agglutination 853:toll-like receptor signaling pathway 2681:The Journal of Biological Chemistry 2611:The Journal of Biological Chemistry 2435:The Journal of Biological Chemistry 2232:The Journal of Biological Chemistry 2197:The Journal of Biological Chemistry 2104:The Journal of Biological Chemistry 1676:The Journal of Biological Chemistry 1592:The Journal of Biological Chemistry 793:positive regulation of phagocytosis 1125: 1104: 1078: 1057: 1033: 1014: 988: 969: 943: 924: 643: 561: 499: 478: 14: 2325:Crouch, E.; Rust, K.; Veile, R.; 2296:The American Journal of Pathology 2038:. 284. 284 ( Pt 3) (3): 795–802. 818:regulation of cytokine production 742:clathrin-coated endocytic vesicle 2916: 2888: 2873: 2858: 2843: 2828: 2813: 2798: 2783: 2768: 647: 409: 402: 396: 373: 308: 301: 295: 270: 27: 2335:Journal of Biological Chemistry 2329:; Grosso, L. (February 1993). 737:endoplasmic reticulum membrane 658:More reference expression data 627:More reference expression data 1: 2536:10.1016/S0969-2126(99)80036-7 2348:10.1016/S0021-9258(18)53869-2 2245:10.1016/S0021-9258(19)49476-3 2210:10.1016/S0021-9258(17)32556-5 2117:10.1016/S0021-9258(19)36824-3 2015:10.1016/s0171-2985(98)80025-9 1605:10.1016/S0021-9258(17)32556-5 838:regulation of immune response 833:defense response to bacterium 803:receptor-mediated endocytosis 394: 293: 2979:Genes on human chromosome 10 2932:. You can help Knowledge by 2659:10.4049/jimmunol.164.11.5866 2176:10.1016/0005-2760(91)90006-4 2147:10.1016/0003-9861(91)90597-C 1975:10.1371/journal.pbio.0060266 1931:10.4049/jimmunol.179.12.8090 1779:10.1371/journal.pbio.0060266 1447:10.1016/0003-9861(91)90597-C 1403:10.1016/0014-5793(94)00383-1 2379:10.1165/ajrcmb.14.2.8630261 772:rough endoplasmic reticulum 3005: 2911: 1878:10.1164/rccm.201004-0654OC 1549:10.1016/j.jaci.2008.02.011 706:lipopolysaccharide binding 551:left lobe of thyroid gland 2763: 1354:"Mouse PubMed Reference:" 1336:"Human PubMed Reference:" 1198: 1193: 1189: 1182: 1166: 1147: 1132: 1111: 1100: 1085: 1064: 1053: 1040: 1036: 1021: 1017: 1008: 995: 991: 976: 972: 963: 950: 946: 931: 927: 918: 903: 896: 892: 876: 843:lung alveolus development 701:identical protein binding 676: 672: 655: 646: 637: 624: 573: 564: 511: 502: 472: 464: 460: 443: 430: 393: 372: 363: 359: 342: 329: 292: 269: 260: 256: 211: 208: 198: 191: 186: 71: 66: 49: 44: 39: 35: 26: 21: 2722:Medical Subject Headings 2624:10.1074/jbc.274.45.32234 2579:10.1073/pnas.96.19.10794 2491:10.1073/pnas.95.20.11869 2448:10.1074/jbc.272.21.13743 1829:10.1165/rcmb.2014-0224OC 1689:10.1074/jbc.272.21.13743 1641:10.1165/ajrcmb.20.4.3439 1160:Chr 14: 40.89 – 40.91 Mb 1153:Chr 10: 79.94 – 79.98 Mb 2036:The Biochemical Journal 1474:The Biochemical Journal 1220:lung surfactant protein 527:upper lobe of left lung 2928:-related article is a 2694:10.1074/jbc.M010191200 2275:10.1006/geno.1993.1324 848:innate immune response 788:surfactant homeostasis 711:monosaccharide binding 2646:Journal of Immunology 1919:Journal of Immunology 868:developmental process 828:macrophage chemotaxis 798:immune system process 427:14 B|14 22.36 cM 388:Chromosome 14 (mouse) 286:Chromosome 10 (human) 2718:Surfactant+Protein+D 1275:pulmonary surfactant 1235:innate immune system 1212:Surfactant protein D 752:extracellular region 696:carbohydrate binding 601:olfactory epithelium 67:List of PDB id codes 40:Available structures 2570:1999PNAS...9610794H 2482:1998PNAS...9511869B 2083:10.1021/bi00163a030 1543:(5): 1140–1147.e2. 1394:1994FEBSL.344..191H 1233:and is part of the 767:multivesicular body 762:extracellular space 613:conjunctival fornix 539:germinal epithelium 2413:10.1101/gr.6.9.791 1239:collagenous region 998:ENSMUSG00000021795 781:Biological process 720:Cellular component 684:Molecular function 523:upper lobe of lung 515:lower lobe of lung 2941: 2940: 2906: 2905: 2238:(31): 23399–408. 2044:10.1042/bj2840795 1729:10.1021/bi4010683 1486:10.1042/bj2840795 1263:influenza A virus 1209: 1208: 1205: 1204: 1178: 1177: 1143: 1142: 1122: 1121: 1096: 1095: 1075: 1074: 1049: 1048: 1030: 1029: 1004: 1003: 985: 984: 959: 958: 940: 939: 888: 887: 747:endocytic vesicle 668: 667: 664: 663: 633: 632: 620: 619: 558: 557: 456: 455: 355: 354: 250:SFTPD - orthologs 182: 181: 178: 177: 50:Ortholog search: 2996: 2962: 2955: 2948: 2920: 2913: 2892: 2877: 2862: 2847: 2832: 2817: 2802: 2787: 2772: 2752: 2745: 2738: 2729: 2706: 2696: 2671: 2661: 2636: 2626: 2617:(45): 32234–40. 2601: 2591: 2581: 2548: 2538: 2513: 2503: 2493: 2476:(20): 11869–74. 2460: 2450: 2425: 2415: 2390: 2360: 2350: 2341:(4): 2976–2983. 2327:Donis-Keller, H. 2321: 2311: 2286: 2257: 2247: 2222: 2212: 2187: 2158: 2129: 2119: 2094: 2065: 2055: 2026: 1997: 1987: 1977: 1952: 1942: 1900: 1899: 1889: 1857: 1851: 1850: 1840: 1808: 1802: 1801: 1791: 1781: 1757: 1751: 1750: 1740: 1708: 1702: 1701: 1691: 1667: 1661: 1660: 1624: 1618: 1617: 1607: 1580: 1571: 1570: 1560: 1528: 1522: 1521: 1514: 1508: 1507: 1497: 1465: 1459: 1458: 1430: 1424: 1423: 1405: 1373: 1362: 1361: 1350: 1344: 1343: 1332: 1326: 1316: 1305: 1295: 1214:, also known as 1191: 1190: 1162: 1155: 1138: 1126: 1117: 1105: 1101:RefSeq (protein) 1091: 1079: 1070: 1058: 1034: 1015: 989: 970: 944: 925: 894: 674: 660: 651: 644: 629: 569: 567:Top expressed in 562: 543:body of pancreas 507: 505:Top expressed in 500: 479: 462: 452: 439: 428: 413: 406: 400: 389: 377: 361: 351: 338: 327: 312: 305: 299: 288: 274: 258: 252: 203: 196: 173: 64: 58: 37: 36: 31: 19: 3004: 3003: 2999: 2998: 2997: 2995: 2994: 2993: 2969: 2968: 2967: 2966: 2909: 2907: 2902: 2899: 2893: 2884: 2878: 2869: 2863: 2854: 2848: 2839: 2833: 2824: 2818: 2809: 2803: 2794: 2788: 2779: 2773: 2759: 2756: 2714: 2709: 2687:(22): 19214–9. 2674: 2652:(11): 5866–70. 2639: 2604: 2564:(19): 10794–9. 2551: 2516: 2463: 2441:(21): 13743–9. 2428: 2400:Genome Research 2393: 2363: 2324: 2289: 2260: 2225: 2203:(25): 17311–9. 2190: 2161: 2132: 2110:(29): 21244–9. 2097: 2077:(48): 12183–9. 2068: 2029: 2000: 1955: 1912: 1908: 1906:Further reading 1903: 1859: 1858: 1854: 1810: 1809: 1805: 1759: 1758: 1754: 1723:(47): 8527–38. 1710: 1709: 1705: 1682:(21): 13743–9. 1669: 1668: 1664: 1626: 1625: 1621: 1598:(25): 17311–9. 1582: 1581: 1574: 1530: 1529: 1525: 1516: 1515: 1511: 1467: 1466: 1462: 1432: 1431: 1427: 1375: 1374: 1365: 1352: 1351: 1347: 1334: 1333: 1329: 1317: 1308: 1296: 1287: 1283: 1271: 1247: 1200:View/Edit Mouse 1195:View/Edit Human 1158: 1151: 1148:Location (UCSC) 1134: 1113: 1087: 1066: 979:ENSG00000133661 872: 776: 715: 691:protein binding 656: 625: 616: 611: 607: 603: 599: 595: 591: 587: 583: 581:right lung lobe 579: 565: 554: 549: 545: 541: 537: 533: 529: 525: 521: 519:visceral pleura 517: 503: 447: 434: 426: 416: 415: 414: 407: 387: 364:Gene location ( 346: 333: 325: 315: 314: 313: 306: 284: 261:Gene location ( 212: 199: 192: 73: 51: 17: 12: 11: 5: 3002: 3000: 2992: 2991: 2986: 2981: 2971: 2970: 2965: 2964: 2957: 2950: 2942: 2939: 2938: 2921: 2904: 2903: 2901: 2900: 2894: 2887: 2885: 2879: 2872: 2870: 2864: 2857: 2855: 2849: 2842: 2840: 2834: 2827: 2825: 2819: 2812: 2810: 2804: 2797: 2795: 2789: 2782: 2780: 2774: 2767: 2764: 2761: 2760: 2757: 2755: 2754: 2747: 2740: 2732: 2726: 2725: 2713: 2712:External links 2710: 2708: 2707: 2672: 2637: 2602: 2549: 2514: 2461: 2426: 2406:(9): 791–806. 2391: 2361: 2322: 2287: 2258: 2223: 2188: 2159: 2130: 2095: 2066: 2027: 1998: 1953: 1925:(12): 8090–7. 1909: 1907: 1904: 1902: 1901: 1852: 1803: 1752: 1703: 1662: 1619: 1572: 1523: 1509: 1480:(3): 795–802. 1460: 1425: 1388:(2–3): 191–5. 1363: 1345: 1327: 1306: 1284: 1282: 1279: 1278: 1277: 1270: 1267: 1246: 1243: 1207: 1206: 1203: 1202: 1197: 1187: 1186: 1180: 1179: 1176: 1175: 1173: 1171: 1164: 1163: 1156: 1149: 1145: 1144: 1141: 1140: 1130: 1129: 1123: 1120: 1119: 1109: 1108: 1102: 1098: 1097: 1094: 1093: 1083: 1082: 1076: 1073: 1072: 1062: 1061: 1055: 1051: 1050: 1047: 1046: 1038: 1037: 1031: 1028: 1027: 1019: 1018: 1012: 1006: 1005: 1002: 1001: 993: 992: 986: 983: 982: 974: 973: 967: 961: 960: 957: 956: 948: 947: 941: 938: 937: 929: 928: 922: 916: 915: 910: 905: 901: 900: 890: 889: 886: 885: 874: 873: 871: 870: 865: 860: 855: 850: 845: 840: 835: 830: 825: 820: 815: 810: 805: 800: 795: 790: 784: 782: 778: 777: 775: 774: 769: 764: 759: 754: 749: 744: 739: 734: 729: 723: 721: 717: 716: 714: 713: 708: 703: 698: 693: 687: 685: 681: 680: 670: 669: 666: 665: 662: 661: 653: 652: 641: 635: 634: 631: 630: 622: 621: 618: 617: 615: 614: 610: 606: 602: 598: 594: 593:lacrimal gland 590: 589:left lung lobe 586: 582: 578: 574: 571: 570: 559: 556: 555: 553: 552: 548: 544: 540: 536: 532: 528: 524: 520: 516: 512: 509: 508: 496: 495: 487: 476: 470: 469: 466:RNA expression 458: 457: 454: 453: 445: 441: 440: 432: 429: 424: 418: 417: 408: 401: 395: 391: 390: 385: 379: 378: 370: 369: 357: 356: 353: 352: 344: 340: 339: 331: 328: 323: 317: 316: 307: 300: 294: 290: 289: 282: 276: 275: 267: 266: 254: 253: 210: 206: 205: 197: 189: 188: 184: 183: 180: 179: 176: 175: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 3001: 2990: 2989:Protein stubs 2987: 2985: 2982: 2980: 2977: 2976: 2974: 2963: 2958: 2956: 2951: 2949: 2944: 2943: 2937: 2935: 2931: 2927: 2922: 2919: 2915: 2910: 2897: 2891: 2886: 2882: 2876: 2871: 2867: 2861: 2856: 2852: 2846: 2841: 2837: 2831: 2826: 2822: 2816: 2811: 2807: 2801: 2796: 2792: 2786: 2781: 2777: 2771: 2766: 2762: 2753: 2748: 2746: 2741: 2739: 2734: 2733: 2730: 2723: 2719: 2716: 2715: 2711: 2704: 2700: 2695: 2690: 2686: 2682: 2678: 2673: 2669: 2665: 2660: 2655: 2651: 2647: 2643: 2638: 2634: 2630: 2625: 2620: 2616: 2612: 2608: 2603: 2599: 2595: 2590: 2585: 2580: 2575: 2571: 2567: 2563: 2559: 2555: 2550: 2546: 2542: 2537: 2532: 2529:(3): 255–64. 2528: 2524: 2520: 2515: 2511: 2507: 2502: 2497: 2492: 2487: 2483: 2479: 2475: 2471: 2467: 2462: 2458: 2454: 2449: 2444: 2440: 2436: 2432: 2427: 2423: 2419: 2414: 2409: 2405: 2401: 2397: 2392: 2388: 2384: 2380: 2376: 2373:(2): 121–30. 2372: 2368: 2362: 2358: 2354: 2349: 2344: 2340: 2336: 2332: 2328: 2323: 2319: 2315: 2310: 2305: 2301: 2297: 2293: 2288: 2284: 2280: 2276: 2272: 2268: 2264: 2259: 2255: 2251: 2246: 2241: 2237: 2233: 2229: 2224: 2220: 2216: 2211: 2206: 2202: 2198: 2194: 2189: 2185: 2181: 2177: 2173: 2170:(2): 185–90. 2169: 2165: 2160: 2156: 2152: 2148: 2144: 2141:(1): 116–26. 2140: 2136: 2131: 2127: 2123: 2118: 2113: 2109: 2105: 2101: 2096: 2092: 2088: 2084: 2080: 2076: 2072: 2067: 2063: 2059: 2054: 2049: 2045: 2041: 2037: 2033: 2028: 2024: 2020: 2016: 2012: 2009:(2): 165–89. 2008: 2004: 2003:Immunobiology 1999: 1995: 1991: 1986: 1981: 1976: 1971: 1967: 1963: 1959: 1954: 1950: 1946: 1941: 1936: 1932: 1928: 1924: 1920: 1916: 1911: 1910: 1905: 1897: 1893: 1888: 1883: 1879: 1875: 1872:(7): 856–64. 1871: 1867: 1863: 1856: 1853: 1848: 1844: 1839: 1834: 1830: 1826: 1823:(1): 96–104. 1822: 1818: 1814: 1807: 1804: 1799: 1795: 1790: 1785: 1780: 1775: 1771: 1767: 1763: 1756: 1753: 1748: 1744: 1739: 1734: 1730: 1726: 1722: 1718: 1714: 1707: 1704: 1699: 1695: 1690: 1685: 1681: 1677: 1673: 1666: 1663: 1658: 1654: 1650: 1646: 1642: 1638: 1635:(4): 759–68. 1634: 1630: 1623: 1620: 1615: 1611: 1606: 1601: 1597: 1593: 1589: 1585: 1579: 1577: 1573: 1568: 1564: 1559: 1554: 1550: 1546: 1542: 1538: 1534: 1527: 1524: 1519: 1513: 1510: 1505: 1501: 1496: 1491: 1487: 1483: 1479: 1475: 1471: 1464: 1461: 1456: 1452: 1448: 1444: 1441:(1): 116–26. 1440: 1436: 1429: 1426: 1421: 1417: 1413: 1409: 1404: 1399: 1395: 1391: 1387: 1383: 1379: 1372: 1370: 1368: 1364: 1359: 1355: 1349: 1346: 1341: 1337: 1331: 1328: 1324: 1320: 1315: 1313: 1311: 1307: 1303: 1299: 1294: 1292: 1290: 1286: 1280: 1276: 1273: 1272: 1268: 1266: 1264: 1260: 1259:hemagglutinin 1256: 1252: 1244: 1242: 1240: 1236: 1232: 1229: 1225: 1221: 1217: 1213: 1201: 1196: 1192: 1188: 1185: 1181: 1174: 1172: 1169: 1165: 1161: 1157: 1154: 1150: 1146: 1139: 1137: 1131: 1127: 1124: 1118: 1116: 1110: 1106: 1103: 1099: 1092: 1090: 1084: 1080: 1077: 1071: 1069: 1063: 1059: 1056: 1054:RefSeq (mRNA) 1052: 1045: 1044: 1039: 1035: 1032: 1026: 1025: 1020: 1016: 1013: 1011: 1007: 1000: 999: 994: 990: 987: 981: 980: 975: 971: 968: 966: 962: 955: 954: 949: 945: 942: 936: 935: 930: 926: 923: 921: 917: 914: 911: 909: 906: 902: 899: 895: 891: 884: 880: 875: 869: 866: 864: 861: 859: 856: 854: 851: 849: 846: 844: 841: 839: 836: 834: 831: 829: 826: 824: 821: 819: 816: 814: 811: 809: 806: 804: 801: 799: 796: 794: 791: 789: 786: 785: 783: 780: 779: 773: 770: 768: 765: 763: 760: 758: 755: 753: 750: 748: 745: 743: 740: 738: 735: 733: 730: 728: 725: 724: 722: 719: 718: 712: 709: 707: 704: 702: 699: 697: 694: 692: 689: 688: 686: 683: 682: 679: 678:Gene ontology 675: 671: 659: 654: 650: 645: 642: 640: 636: 628: 623: 612: 608: 605:parotid gland 604: 600: 596: 592: 588: 584: 580: 576: 575: 572: 568: 563: 560: 550: 546: 542: 538: 534: 530: 526: 522: 518: 514: 513: 510: 506: 501: 498: 497: 494: 492: 488: 486: 485: 481: 480: 477: 475: 471: 467: 463: 459: 451: 446: 442: 438: 433: 423: 419: 412: 405: 399: 392: 384: 380: 376: 371: 367: 362: 358: 350: 345: 341: 337: 332: 322: 318: 311: 304: 298: 291: 287: 281: 277: 273: 268: 264: 259: 255: 251: 247: 243: 239: 235: 231: 227: 223: 219: 215: 207: 202: 195: 190: 185: 174: 172: 168: 164: 160: 156: 152: 148: 144: 140: 136: 132: 128: 124: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 2934:expanding it 2923: 2908: 2895: 2880: 2865: 2850: 2835: 2820: 2805: 2790: 2775: 2684: 2680: 2649: 2645: 2614: 2610: 2561: 2557: 2526: 2522: 2473: 2469: 2438: 2434: 2403: 2399: 2370: 2366: 2338: 2334: 2302:(1): 241–8. 2299: 2295: 2269:(2): 294–8. 2266: 2262: 2235: 2231: 2200: 2196: 2167: 2163: 2138: 2134: 2107: 2103: 2074: 2071:Biochemistry 2070: 2035: 2006: 2002: 1968:(11): e266. 1965: 1962:PLOS Biology 1961: 1922: 1918: 1869: 1865: 1855: 1820: 1816: 1806: 1772:(11): e266. 1769: 1766:PLOS Biology 1765: 1755: 1720: 1717:Biochemistry 1716: 1706: 1679: 1675: 1665: 1632: 1628: 1622: 1595: 1591: 1540: 1536: 1526: 1512: 1477: 1473: 1463: 1438: 1434: 1428: 1385: 1382:FEBS Letters 1381: 1357: 1348: 1339: 1330: 1248: 1245:Interactions 1227: 1215: 1211: 1210: 1133: 1112: 1086: 1065: 1041: 1022: 996: 977: 951: 932: 912: 907: 489: 482: 209:External IDs 72: 2758:PDB gallery 547:skin of leg 448:40,907,106 435:40,894,171 347:79,982,614 334:79,937,467 187:Identifiers 2984:Collectins 2973:Categories 1325:, May 2017 1304:, May 2017 1281:References 577:right lung 531:right lung 493:(ortholog) 230:HomoloGene 2523:Structure 1224:collectin 1136:NP_033186 1115:NP_003010 1089:NM_009160 1068:NM_003019 898:Orthologs 727:cytoplasm 585:left lung 238:GeneCards 2703:11278637 2668:10820266 2633:10542261 2598:10485905 2545:10368295 2263:Genomics 1994:19007302 1949:18056350 1896:21131470 1847:25474372 1798:19007302 1747:24224757 1657:29437779 1649:10101009 1584:Crouch E 1567:18355911 1321:– 1300:– 1269:See also 1251:interact 1184:Wikidata 877:Sources: 757:lysosome 732:collagen 535:testicle 2926:protein 2566:Bibcode 2510:9751757 2478:Bibcode 2457:9153228 2422:8889548 2387:8630261 2357:8428971 2318:8424457 2309:1886847 2283:8406480 2254:8226864 2219:8006040 2184:1932100 2155:1898081 2126:1400434 2091:1457414 2062:1339284 2053:1132609 2023:9777404 1985:2581630 1940:4009628 1887:3086753 1838:4566108 1789:2581630 1738:3927399 1698:9153228 1614:8006040 1558:4145593 1504:1339284 1495:1132609 1476:. 284. 1455:1898081 1420:2920539 1412:8187882 1390:Bibcode 1323:Ensembl 1302:Ensembl 1218:, is a 1010:UniProt 965:Ensembl 904:Species 883:QuickGO 597:trachea 468:pattern 326:10q22.3 194:Aliases 2724:(MeSH) 2701:  2666:  2631:  2596:  2586:  2543:  2508:  2498:  2455:  2420:  2385:  2355:  2316:  2306:  2281:  2252:  2217:  2182:  2153:  2124:  2089:  2060:  2050:  2021:  1992:  1982:  1947:  1937:  1894:  1884:  1845:  1835:  1796:  1786:  1745:  1735:  1696:  1655:  1647:  1612:  1565:  1555:  1502:  1492:  1453:  1418:  1410:  1257:, and 1170:search 1168:PubMed 1043:P50404 1024:P35247 920:Entrez 639:BioGPS 609:uterus 226:109515 218:178635 2924:This 2589:17962 2501:21732 1653:S2CID 1416:S2CID 1255:DMBT1 1253:with 1228:SFTPD 953:20390 913:Mouse 908:Human 879:Amigo 491:Mouse 484:Human 431:Start 366:Mouse 330:Start 263:Human 242:SFTPD 201:SFTPD 22:SFTPD 2930:stub 2896:2os9 2881:2ork 2866:2orj 2851:2ggx 2836:2ggu 2821:1pwb 2806:1pw9 2791:1m7l 2776:1b08 2699:PMID 2664:PMID 2629:PMID 2594:PMID 2541:PMID 2506:PMID 2453:PMID 2418:PMID 2383:PMID 2353:PMID 2314:PMID 2279:PMID 2250:PMID 2215:PMID 2180:PMID 2168:1086 2151:PMID 2122:PMID 2087:PMID 2058:PMID 2019:PMID 1990:PMID 1945:PMID 1892:PMID 1843:PMID 1794:PMID 1743:PMID 1694:PMID 1645:PMID 1610:PMID 1563:PMID 1500:PMID 1451:PMID 1408:PMID 1231:gene 1216:SP-D 934:6441 474:Bgee 422:Band 383:Chr. 321:Band 280:Chr. 234:2272 214:OMIM 171:4M18 167:4M17 163:4E52 159:3IKR 155:3IKQ 151:3IKP 147:3IKN 143:3G84 139:3G83 135:3G81 131:3DBZ 127:2RIE 123:2RID 119:2RIC 115:2RIB 111:2RIA 107:2OS9 103:2ORK 99:2ORJ 95:2GGX 91:2GGU 87:1PWB 83:1PW9 79:1M7L 75:1B08 56:RCSB 53:PDBe 2689:doi 2685:276 2654:doi 2650:164 2619:doi 2615:274 2584:PMC 2574:doi 2531:doi 2496:PMC 2486:doi 2443:doi 2439:272 2408:doi 2375:doi 2343:doi 2339:268 2304:PMC 2300:142 2271:doi 2240:doi 2236:268 2205:doi 2201:269 2172:doi 2143:doi 2139:290 2112:doi 2108:267 2079:doi 2048:PMC 2040:doi 2011:doi 2007:199 1980:PMC 1970:doi 1935:PMC 1927:doi 1923:179 1882:PMC 1874:doi 1870:183 1833:PMC 1825:doi 1784:PMC 1774:doi 1733:PMC 1725:doi 1684:doi 1680:272 1637:doi 1600:doi 1596:269 1553:PMC 1545:doi 1541:121 1490:PMC 1482:doi 1478:284 1443:doi 1439:290 1398:doi 1386:344 1261:of 444:End 343:End 246:OMA 222:MGI 46:PDB 2975:: 2697:. 2683:. 2679:. 2662:. 2648:. 2644:. 2627:. 2613:. 2609:. 2592:. 2582:. 2572:. 2562:96 2560:. 2556:. 2539:. 2525:. 2521:. 2504:. 2494:. 2484:. 2474:95 2472:. 2468:. 2451:. 2437:. 2433:. 2416:. 2402:. 2398:. 2381:. 2371:14 2369:. 2351:. 2337:. 2333:. 2312:. 2298:. 2294:. 2277:. 2267:17 2265:. 2248:. 2234:. 2230:. 2213:. 2199:. 2195:. 2178:. 2166:. 2149:. 2137:. 2120:. 2106:. 2102:. 2085:. 2075:31 2073:. 2056:. 2046:. 2034:. 2017:. 2005:. 1988:. 1978:. 1964:. 1960:. 1943:. 1933:. 1921:. 1917:. 1890:. 1880:. 1868:. 1864:. 1841:. 1831:. 1821:53 1819:. 1815:. 1792:. 1782:. 1768:. 1764:. 1741:. 1731:. 1721:52 1719:. 1715:. 1692:. 1678:. 1674:. 1651:. 1643:. 1633:20 1631:. 1608:. 1594:. 1590:. 1575:^ 1561:. 1551:. 1539:. 1535:. 1498:. 1488:. 1472:. 1449:. 1437:. 1414:. 1406:. 1396:. 1384:. 1380:. 1366:^ 1356:. 1338:. 1309:^ 1288:^ 881:/ 450:bp 437:bp 349:bp 336:bp 244:; 240:: 236:; 232:: 228:; 224:: 220:; 216:: 169:, 165:, 161:, 157:, 153:, 149:, 145:, 141:, 137:, 133:, 129:, 125:, 121:, 117:, 113:, 109:, 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 2961:e 2954:t 2947:v 2936:. 2751:e 2744:t 2737:v 2705:. 2691:: 2670:. 2656:: 2635:. 2621:: 2600:. 2576:: 2568:: 2547:. 2533:: 2527:7 2512:. 2488:: 2480:: 2459:. 2445:: 2424:. 2410:: 2404:6 2389:. 2377:: 2359:. 2345:: 2320:. 2285:. 2273:: 2256:. 2242:: 2221:. 2207:: 2186:. 2174:: 2157:. 2145:: 2128:. 2114:: 2093:. 2081:: 2064:. 2042:: 2025:. 2013:: 1996:. 1972:: 1966:6 1951:. 1929:: 1898:. 1876:: 1849:. 1827:: 1800:. 1776:: 1770:6 1749:. 1727:: 1700:. 1686:: 1659:. 1639:: 1616:. 1602:: 1569:. 1547:: 1520:. 1506:. 1484:: 1457:. 1445:: 1422:. 1400:: 1392:: 1360:. 1342:. 368:) 265:) 248::

Index


PDB
PDBe
RCSB
1B08
1M7L
1PW9
1PWB
2GGU
2GGX
2ORJ
2ORK
2OS9
2RIA
2RIB
2RIC
2RID
2RIE
3DBZ
3G81
3G83
3G84
3IKN
3IKP
3IKQ
3IKR
4E52
4M17
4M18
Aliases

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