253:
230:
127:
152:
504:
259:
158:
1441:
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001).
1105:
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997).
1853:
Hirakawa M, Tsuruya K, Yotsueda H, Tokumoto M, Ikeda H, Katafuchi R, Fujimi S, Hirakata H, Iida M (Jul 2006). "Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis".
1686:
Kremerskothen J, Plaas C, Kindler S, Frotscher M, Barnekow A (Feb 2005). "Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding protein".
1883:
Asanuma K, Yanagida-Asanuma E, Faul C, Tomino Y, Kim K, Mundel P (May 2006). "Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling".
1649:
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (Jan 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells".
1810:
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006).
266:
165:
1268:"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro"
792:
773:
88:
1606:
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004).
1199:
1181:
2008:
252:
1024:
1031:
229:
1965:"Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia"
1310:
1370:
Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O (Sep 1995).
1168:
1147:
1164:
151:
126:
1371:
1143:
1444:"Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs"
68:
1372:"Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence"
1115:
1565:"Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways"
1487:"Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1"
1326:"Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1"
265:
164:
258:
157:
837:
76:
818:
1522:"Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions"
1520:
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S (Sep 2004).
1266:
Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1999).
140:
55:
1726:"Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner"
1003:
978:
974:
970:
940:
915:
911:
907:
1963:
Garovic VD, Wagner SJ, Petrovic LM, Gray CE, Hall P, Sugimoto H, Kalluri R, Grande JP (Apr 2007).
1951:
1908:
1798:
1712:
1674:
100:
1007:
982:
944:
919:
1986:
1943:
1900:
1871:
1841:
1790:
1755:
1704:
1666:
1637:
1594:
1551:
1508:
1473:
1429:
1386:
1347:
1289:
1248:
48:
1769:"HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN"
1976:
1933:
1892:
1863:
1831:
1823:
1780:
1745:
1737:
1696:
1658:
1627:
1619:
1584:
1576:
1541:
1533:
1498:
1463:
1455:
1419:
1411:
1337:
1279:
1238:
1230:
345:
276:
220:
175:
503:
96:
1219:"Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes"
320:
1785:
1768:
1836:
1811:
1750:
1725:
1724:
Asanuma K, Kim K, Oh J, Giardino L, Chabanis S, Faul C, Reiser J, Mundel P (May 2005).
1563:
He JC, Husain M, Sunamoto M, D'Agati VD, Klotman ME, Iyengar R, Klotman PE (Sep 2004).
1243:
1218:
1632:
1607:
1589:
1564:
1546:
1521:
1468:
1443:
1424:
1399:
707:
702:
697:
692:
687:
682:
677:
672:
656:
651:
646:
641:
636:
631:
626:
621:
616:
611:
606:
601:
596:
591:
586:
581:
576:
571:
566:
550:
545:
2002:
1700:
532:
1912:
1802:
80:
1955:
1922:"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks"
1716:
1678:
338:
117:
104:
1204:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1186:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1938:
1921:
1920:
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006).
421:
1867:
237:
134:
84:
1284:
1267:
737:
481:
359:
304:
291:
203:
190:
92:
17:
1990:
1947:
1904:
1875:
1845:
1794:
1759:
1708:
1670:
1641:
1598:
1555:
1512:
1503:
1486:
1477:
1433:
1351:
1342:
1325:
1293:
1390:
1252:
1234:
1071:
1066:
1981:
1964:
1827:
1055:
882:
863:
1623:
1537:
1459:
1087:
849:
804:
1485:
Patrie KM, Drescher AJ, Welihinda A, Mundel P, Margolis B (Aug 2002).
1415:
1324:
Patrie KM, Drescher AJ, Welihinda A, Mundel P, Margolis B (Aug 2002).
1741:
1580:
1217:
Mundel P, Heid HW, Mundel TM, Krüger M, Reiser J, Kriz W (Oct 1997).
1039:
759:
1896:
1662:
708:
positive regulation of postsynaptic cytosolic calcium concentration
1119:
722:
718:
1767:
Husain M, D'Agati VD, He JC, Klotman ME, Klotman PE (Nov 2005).
1094:
512:
72:
1608:"From ORFeome to biology: a functional genomics pipeline"
703:
postsynaptic modulation of chemical synaptic transmission
1400:"DNA cloning using in vitro site-specific recombination"
328:
673:
positive regulation of actin filament bundle assembly
493:
693:
regulation of long-term neuronal synaptic plasticity
996:
963:
933:
900:
456:
dentate gyrus of hippocampal formation granule cell
1160:
1158:
1156:
1139:
1137:
1135:
275:
174:
1165:GRCm38: Ensembl release 89: ENSMUSG00000043079
1398:Hartley JL, Temple GF, Brasch MA (Nov 2000).
8:
1144:GRCh38: Ensembl release 89: ENSG00000171992
733:
528:
386:Skeletal muscle tissue of rectus abdominis
316:
215:
112:
1980:
1937:
1835:
1784:
1749:
1631:
1588:
1545:
1502:
1467:
1423:
1341:
1283:
1242:
1305:
1303:
1131:
27:Mammalian protein found in Homo sapiens
29:
1969:Nephrology, Dialysis, Transplantation
1730:The Journal of Clinical Investigation
1569:The Journal of Clinical Investigation
280:
241:
236:
179:
138:
133:
7:
1786:10.1097/01.aids.0000191918.42110.27
1491:The Journal of Biological Chemistry
1330:The Journal of Biological Chemistry
678:regulation of stress fiber assembly
993:
960:
930:
897:
873:
854:
828:
809:
783:
764:
498:
416:
354:
333:
25:
1311:"Entrez Gene: SYNPO synaptopodin"
1090:that in humans is encoded by the
652:Schaffer collateral - CA1 synapse
1701:10.1111/j.1471-4159.2004.02888.x
502:
264:
257:
251:
228:
163:
156:
150:
125:
698:modification of dendritic spine
513:More reference expression data
482:More reference expression data
1:
1812:"The LIFEdb database in 2006"
448:tunica media of zone of aorta
249:
148:
2009:Genes on human chromosome 5
1223:The Journal of Cell Biology
2025:
1939:10.1016/j.cell.2006.09.026
1822:(Database issue): D415-8.
1868:10.1016/j.lfs.2006.02.031
1689:Journal of Neurochemistry
1200:"Mouse PubMed Reference:"
1182:"Human PubMed Reference:"
1070:
1065:
1061:
1054:
1038:
1019:
1000:
967:
956:
937:
904:
893:
880:
876:
861:
857:
848:
835:
831:
816:
812:
803:
790:
786:
771:
767:
758:
743:
736:
732:
716:
622:bicellular tight junction
531:
527:
510:
501:
492:
479:
428:
419:
378:Descending thoracic aorta
366:
357:
327:
319:
315:
298:
285:
248:
227:
218:
214:
197:
184:
147:
124:
115:
111:
66:
63:
53:
46:
41:
37:
32:
1114:SYNPO has been shown to
1032:Chr 18: 60.73 – 60.79 Mb
1025:Chr 5: 150.6 – 150.66 Mb
683:spine apparatus assembly
402:tendon of biceps brachii
444:external carotid artery
1816:Nucleic Acids Research
1504:10.1074/jbc.M203072200
1343:10.1074/jbc.M203072200
1285:10.1093/dnares/6.3.197
460:superior frontal gyrus
452:lumbar spinal ganglion
1385:(6547 Suppl): 3–174.
1235:10.1083/jcb.139.1.193
657:glutamatergic synapse
582:postsynaptic membrane
394:right coronary artery
243:Chromosome 18 (mouse)
1651:Nature Biotechnology
617:postsynaptic density
382:gastrocnemius muscle
141:Chromosome 5 (human)
1885:Nature Cell Biology
1982:10.1093/ndt/gfl711
1828:10.1093/nar/gkj139
1624:10.1101/gr.2576704
1538:10.1101/gr.2435604
1460:10.1101/gr.GR1547R
838:ENSMUSG00000043079
666:Biological process
637:actin cytoskeleton
560:Cellular component
539:Molecular function
1416:10.1101/gr.143000
1081:
1080:
1077:
1076:
1050:
1049:
1015:
1014:
990:
989:
952:
951:
927:
926:
889:
888:
870:
869:
844:
843:
825:
824:
799:
798:
780:
779:
728:
727:
523:
522:
519:
518:
488:
487:
475:
474:
413:
412:
311:
310:
282:18|18 D3- E1
210:
209:
105:SYNPO - orthologs
16:(Redirected from
2016:
1994:
1984:
1959:
1941:
1916:
1879:
1849:
1839:
1806:
1788:
1763:
1753:
1742:10.1172/JCI23371
1720:
1682:
1645:
1635:
1618:(10B): 2136–44.
1602:
1592:
1581:10.1172/JCI21004
1559:
1549:
1516:
1506:
1497:(33): 30183–90.
1481:
1471:
1437:
1427:
1394:
1376:
1356:
1355:
1345:
1336:(33): 30183–90.
1321:
1315:
1314:
1307:
1298:
1297:
1287:
1263:
1257:
1256:
1246:
1214:
1208:
1207:
1196:
1190:
1189:
1178:
1172:
1162:
1151:
1141:
1063:
1062:
1034:
1027:
1010:
994:
985:
961:
957:RefSeq (protein)
947:
931:
922:
898:
874:
855:
829:
810:
784:
765:
734:
529:
515:
506:
499:
484:
424:
422:Top expressed in
417:
362:
360:Top expressed in
355:
334:
317:
307:
294:
283:
268:
261:
255:
244:
232:
216:
206:
193:
182:
167:
160:
154:
143:
129:
113:
107:
58:
51:
30:
21:
2024:
2023:
2019:
2018:
2017:
2015:
2014:
2013:
1999:
1998:
1997:
1962:
1919:
1897:10.1038/ncb1400
1882:
1852:
1809:
1779:(17): 1975–80.
1766:
1723:
1685:
1663:10.1038/nbt1046
1648:
1612:Genome Research
1605:
1562:
1526:Genome Research
1519:
1484:
1448:Genome Research
1440:
1410:(11): 1788–95.
1404:Genome Research
1397:
1374:
1369:
1365:
1363:Further reading
1360:
1359:
1323:
1322:
1318:
1309:
1308:
1301:
1265:
1264:
1260:
1216:
1215:
1211:
1198:
1197:
1193:
1180:
1179:
1175:
1163:
1154:
1142:
1133:
1128:
1112:
1103:
1072:View/Edit Mouse
1067:View/Edit Human
1030:
1023:
1020:Location (UCSC)
1006:
1002:
981:
977:
973:
969:
943:
939:
918:
914:
910:
906:
819:ENSG00000171992
712:
688:visual learning
661:
647:spine apparatus
597:cell projection
592:plasma membrane
587:dendritic spine
555:
546:protein binding
511:
480:
471:
466:
462:
458:
454:
450:
446:
442:
440:muscle of thigh
438:
434:
432:ascending aorta
420:
409:
404:
400:
396:
392:
390:ascending aorta
388:
384:
380:
376:
372:
370:muscle of thigh
358:
302:
289:
281:
271:
270:
269:
262:
242:
219:Gene location (
201:
188:
180:
170:
169:
168:
161:
139:
116:Gene location (
67:
54:
47:
28:
23:
22:
15:
12:
11:
5:
2022:
2020:
2012:
2011:
2001:
2000:
1996:
1995:
1975:(4): 1136–43.
1960:
1917:
1880:
1850:
1807:
1764:
1736:(5): 1188–98.
1721:
1695:(3): 597–606.
1683:
1646:
1603:
1560:
1517:
1482:
1438:
1395:
1366:
1364:
1361:
1358:
1357:
1316:
1299:
1278:(3): 197–205.
1258:
1229:(1): 193–204.
1209:
1191:
1173:
1152:
1130:
1129:
1127:
1124:
1111:
1108:
1102:
1099:
1079:
1078:
1075:
1074:
1069:
1059:
1058:
1052:
1051:
1048:
1047:
1045:
1043:
1036:
1035:
1028:
1021:
1017:
1016:
1013:
1012:
998:
997:
991:
988:
987:
965:
964:
958:
954:
953:
950:
949:
935:
934:
928:
925:
924:
902:
901:
895:
891:
890:
887:
886:
878:
877:
871:
868:
867:
859:
858:
852:
846:
845:
842:
841:
833:
832:
826:
823:
822:
814:
813:
807:
801:
800:
797:
796:
788:
787:
781:
778:
777:
769:
768:
762:
756:
755:
750:
745:
741:
740:
730:
729:
726:
725:
714:
713:
711:
710:
705:
700:
695:
690:
685:
680:
675:
669:
667:
663:
662:
660:
659:
654:
649:
644:
639:
634:
629:
624:
619:
614:
609:
604:
599:
594:
589:
584:
579:
574:
569:
563:
561:
557:
556:
554:
553:
548:
542:
540:
536:
535:
525:
524:
521:
520:
517:
516:
508:
507:
496:
490:
489:
486:
485:
477:
476:
473:
472:
470:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
429:
426:
425:
414:
411:
410:
408:
407:
406:left ventricle
403:
399:
395:
391:
387:
383:
379:
375:
371:
367:
364:
363:
351:
350:
342:
331:
325:
324:
321:RNA expression
313:
312:
309:
308:
300:
296:
295:
287:
284:
279:
273:
272:
263:
256:
250:
246:
245:
240:
234:
233:
225:
224:
212:
211:
208:
207:
199:
195:
194:
186:
183:
178:
172:
171:
162:
155:
149:
145:
144:
137:
131:
130:
122:
121:
109:
108:
65:
61:
60:
59:, synaptopodin
52:
44:
43:
39:
38:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2021:
2010:
2007:
2006:
2004:
1992:
1988:
1983:
1978:
1974:
1970:
1966:
1961:
1957:
1953:
1949:
1945:
1940:
1935:
1932:(3): 635–48.
1931:
1927:
1923:
1918:
1914:
1910:
1906:
1902:
1898:
1894:
1891:(5): 485–91.
1890:
1886:
1881:
1877:
1873:
1869:
1865:
1862:(8): 757–63.
1861:
1857:
1856:Life Sciences
1851:
1847:
1843:
1838:
1833:
1829:
1825:
1821:
1817:
1813:
1808:
1804:
1800:
1796:
1792:
1787:
1782:
1778:
1774:
1770:
1765:
1761:
1757:
1752:
1747:
1743:
1739:
1735:
1731:
1727:
1722:
1718:
1714:
1710:
1706:
1702:
1698:
1694:
1690:
1684:
1680:
1676:
1672:
1668:
1664:
1660:
1657:(1): 94–101.
1656:
1652:
1647:
1643:
1639:
1634:
1629:
1625:
1621:
1617:
1613:
1609:
1604:
1600:
1596:
1591:
1586:
1582:
1578:
1575:(5): 643–51.
1574:
1570:
1566:
1561:
1557:
1553:
1548:
1543:
1539:
1535:
1532:(9): 1711–8.
1531:
1527:
1523:
1518:
1514:
1510:
1505:
1500:
1496:
1492:
1488:
1483:
1479:
1475:
1470:
1465:
1461:
1457:
1454:(3): 422–35.
1453:
1449:
1445:
1439:
1435:
1431:
1426:
1421:
1417:
1413:
1409:
1405:
1401:
1396:
1392:
1388:
1384:
1380:
1373:
1368:
1367:
1362:
1353:
1349:
1344:
1339:
1335:
1331:
1327:
1320:
1317:
1312:
1306:
1304:
1300:
1295:
1291:
1286:
1281:
1277:
1273:
1269:
1262:
1259:
1254:
1250:
1245:
1240:
1236:
1232:
1228:
1224:
1220:
1213:
1210:
1205:
1201:
1195:
1192:
1187:
1183:
1177:
1174:
1170:
1166:
1161:
1159:
1157:
1153:
1149:
1145:
1140:
1138:
1136:
1132:
1125:
1123:
1121:
1117:
1109:
1107:
1100:
1098:
1096:
1093:
1089:
1085:
1073:
1068:
1064:
1060:
1057:
1053:
1046:
1044:
1041:
1037:
1033:
1029:
1026:
1022:
1018:
1011:
1009:
1005:
999:
995:
992:
986:
984:
980:
976:
972:
966:
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948:
946:
942:
936:
932:
929:
923:
921:
917:
913:
909:
903:
899:
896:
894:RefSeq (mRNA)
892:
885:
884:
879:
875:
872:
866:
865:
860:
856:
853:
851:
847:
840:
839:
834:
830:
827:
821:
820:
815:
811:
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795:
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789:
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766:
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731:
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709:
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623:
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583:
580:
578:
577:cell junction
575:
573:
570:
568:
565:
564:
562:
559:
558:
552:
551:actin binding
549:
547:
544:
543:
541:
538:
537:
534:
533:Gene ontology
530:
526:
514:
509:
505:
500:
497:
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491:
483:
478:
467:
463:
459:
455:
451:
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431:
430:
427:
423:
418:
415:
405:
401:
398:right auricle
397:
393:
389:
385:
381:
377:
374:apex of heart
373:
369:
368:
365:
361:
356:
353:
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336:
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136:
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98:
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90:
86:
82:
78:
74:
70:
62:
57:
50:
45:
40:
36:
31:
19:
1972:
1968:
1929:
1925:
1888:
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1859:
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1815:
1776:
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1733:
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1692:
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1611:
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1525:
1494:
1490:
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1447:
1407:
1403:
1382:
1378:
1333:
1329:
1319:
1275:
1272:DNA Research
1271:
1261:
1226:
1222:
1212:
1203:
1194:
1185:
1176:
1113:
1110:Interactions
1104:
1091:
1084:Synaptopodin
1083:
1082:
1004:NP_001103445
1001:
979:NP_001159681
975:NP_001159680
971:NP_001103444
968:
941:NM_001109975
938:
916:NM_001166209
912:NM_001166208
908:NM_001109974
905:
881:
862:
836:
817:
791:
772:
752:
747:
642:stress fiber
607:cytoskeleton
464:cumulus cell
436:aortic valve
344:
337:
202:150,659,207
189:150,601,080
64:External IDs
18:Synaptopodin
468:ankle joint
303:60,793,214
290:60,727,045
42:Identifiers
1171:, May 2017
1150:, May 2017
1126:References
627:Z discdkac
572:perikaryon
348:(ortholog)
85:HomoloGene
1008:NP_796314
983:NP_009217
945:NM_177340
920:NM_007286
738:Orthologs
567:cytoplasm
93:GeneCards
2003:Category
1991:17255128
1948:17081983
1913:12861229
1905:16622418
1876:16564554
1846:16381901
1803:40286329
1795:16260903
1760:15841212
1709:15659229
1671:15592455
1642:15489336
1599:15343382
1556:15342556
1513:12042308
1478:11230166
1434:11076863
1352:12042308
1294:10470851
1167:–
1146:–
1116:interact
1101:Function
1056:Wikidata
717:Sources:
612:membrane
1956:7827573
1837:1347501
1751:1070637
1717:1837841
1679:7200157
1391:7566098
1253:9314539
1244:2139823
1169:Ensembl
1148:Ensembl
1088:protein
850:UniProt
805:Ensembl
744:Species
723:QuickGO
632:nucleus
602:synapse
323:pattern
81:1099446
49:Aliases
1989:
1954:
1946:
1911:
1903:
1874:
1844:
1834:
1801:
1793:
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1669:
1640:
1633:528930
1630:
1597:
1590:514582
1587:
1554:
1547:515316
1544:
1511:
1476:
1469:311072
1466:
1432:
1425:310948
1422:
1389:
1379:Nature
1350:
1292:
1251:
1241:
1042:search
1040:PubMed
883:Q8CC35
864:Q8N3V7
793:104027
760:Entrez
494:BioGPS
181:5q33.1
73:608155
1952:S2CID
1909:S2CID
1799:S2CID
1713:S2CID
1675:S2CID
1375:(PDF)
1120:MAGI1
1118:with
1092:SYNPO
1086:is a
774:11346
753:Mouse
748:Human
719:Amigo
346:Mouse
339:Human
286:Start
221:Mouse
185:Start
118:Human
97:SYNPO
56:SYNPO
33:SYNPO
1987:PMID
1944:PMID
1926:Cell
1901:PMID
1872:PMID
1842:PMID
1791:PMID
1773:AIDS
1756:PMID
1705:PMID
1667:PMID
1638:PMID
1595:PMID
1552:PMID
1509:PMID
1474:PMID
1430:PMID
1387:PMID
1348:PMID
1290:PMID
1249:PMID
1095:gene
329:Bgee
277:Band
238:Chr.
176:Band
135:Chr.
89:5274
69:OMIM
1977:doi
1934:doi
1930:127
1893:doi
1864:doi
1832:PMC
1824:doi
1781:doi
1746:PMC
1738:doi
1734:115
1697:doi
1659:doi
1628:PMC
1620:doi
1585:PMC
1577:doi
1573:114
1542:PMC
1534:doi
1499:doi
1495:277
1464:PMC
1456:doi
1420:PMC
1412:doi
1383:377
1338:doi
1334:277
1280:doi
1239:PMC
1231:doi
1227:139
299:End
198:End
101:OMA
77:MGI
2005::
1985:.
1973:22
1971:.
1967:.
1950:.
1942:.
1928:.
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1907:.
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1328:.
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1184:.
1155:^
1134:^
1122:.
1097:.
721:/
305:bp
292:bp
204:bp
191:bp
99:;
95::
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87::
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79::
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71::
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1255:.
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