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Synthetic crystalline bovine insulin

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193: 31:), which was the first functional crystalline protein being fully synthesized in the world. Research on synthesizing bovine insulin started on 1958. Members in the research group were from the Chemistry Department of 74:) consisting of two chain, A and B. Chain A consists of 21 amino acid residues while chain consists of 30 amino acid residues. The main function of insulin is to regulate the concentrate of sugar in blood. 206: 89:, a team member who had made significant contributions, for the Nobel Chemistry Prize, but the nomination was unsuccessful. 56: 48: 36: 24: 259: 108: 78:
are caused by dysfunction on the synthesis or secretory of insulin while injecting insulin can treat type 1 diabetes.
44: 225: 192: 254: 249: 103: 32: 181: 171: 163: 75: 176: 151: 243: 210: 131:) (2015). "对人工合成结晶牛胰岛素的回忆(Memory on the research of synthesizing bovine insulin)". 82: 128: 98: 226:"中国人对诺贝尔奖的病态痴迷源自何处? (Why Chinese People are so obsessive on the Nobel Prize?)" 167: 86: 185: 229: 207:"揭秘我国首次申报诺贝尔奖始末(Revealing the First Application to Nobel Prize in China)" 71: 67: 19: 209:(in Chinese). People's Daily. 2005-10-08. Archived from 152:"The creation of synthetic crystalline bovine insulin" 55:) and Shanghai Institute of Organic Chemistry, CAS ( 16:In 1965, Chinese scientists first synthesized 8: 85:, the project's lead scientist, nominated 175: 120: 43:), Shanghai Institute of Biochemistry, 133:生命科学(Chinese Bulletin of Life Science) 7: 14: 191: 60: 52: 40: 28: 1: 109:Cell-free protein synthesis 276: 224:李岩(Yan Li) (2016-12-24). 168:10.1007/s13238-015-0221-x 228:. Tecent. Archived from 104:Panayotis Katsoyannis 150:Yeping Sun (2015). 18:crystalline bovine 260:Chinese inventions 33:Beijing University 267: 234: 233: 221: 215: 214: 203: 197: 196: 195: 189: 179: 147: 141: 140: 125: 62: 54: 42: 30: 275: 274: 270: 269: 268: 266: 265: 264: 240: 239: 238: 237: 223: 222: 218: 205: 204: 200: 190: 162:(11): 781–783. 149: 148: 144: 127: 126: 122: 117: 95: 76:Type 1 diabetes 12: 11: 5: 273: 271: 263: 262: 257: 252: 242: 241: 236: 235: 232:on 2018-04-21. 216: 213:on 2014-07-09. 198: 142: 135:(in Chinese). 119: 118: 116: 113: 112: 111: 106: 101: 94: 91: 13: 10: 9: 6: 4: 3: 2: 272: 261: 258: 256: 255:1965 in China 253: 251: 248: 247: 245: 231: 227: 220: 217: 212: 208: 202: 199: 194: 187: 183: 178: 173: 169: 165: 161: 157: 153: 146: 143: 139:(6): 777–779. 138: 134: 130: 124: 121: 114: 110: 107: 105: 102: 100: 97: 96: 92: 90: 88: 84: 79: 77: 73: 69: 66:Insulin is a 64: 58: 50: 46: 38: 34: 26: 22: 21: 250:Biochemistry 230:the original 219: 211:the original 201: 159: 156:Protein Cell 155: 145: 136: 132: 123: 83:Wang Yinglai 80: 65: 61:中科院上海有机化学研究所 53:中科院上海生物化学研究所 17: 15: 129:Zou Chenglu 99:Helmut Zahn 244:Categories 115:References 87:Niu Jingyi 29:人工合成结晶牛胰岛素 81:In 1979, 186:26487565 93:See also 177:4624679 72:peptide 68:protein 57:Chinese 49:Chinese 41:北京大学化学系 37:Chinese 25:Chinese 20:insulin 184:  174:  59:: 51:: 39:: 27:: 182:PMID 172:PMC 164:doi 63:). 45:CAS 246:: 180:. 170:. 158:. 154:. 137:27 188:. 166:: 160:6 70:( 47:( 35:( 23:(

Index

insulin
Chinese
Beijing University
Chinese
CAS
Chinese
Chinese
protein
peptide
Type 1 diabetes
Wang Yinglai
Niu Jingyi
Helmut Zahn
Panayotis Katsoyannis
Cell-free protein synthesis
Zou Chenglu
"The creation of synthetic crystalline bovine insulin"
doi
10.1007/s13238-015-0221-x
PMC
4624679
PMID
26487565
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"揭秘我国首次申报诺贝尔奖始末(Revealing the First Application to Nobel Prize in China)"
the original
"中国人对诺贝尔奖的病态痴迷源自何处? (Why Chinese People are so obsessive on the Nobel Prize?)"
the original
Categories
Biochemistry

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