Knowledge (XXG)

SEMA4D

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Deborah A. Witherden, Megumi Watanabe, Olivia Garijo, Stephanie E. Rieder, Gor Sarkisyan, Shane J.F. Cronin, Petra Verdino, Ian A. Wilson, Atsushi Kumanogoh, Hitoshi Kikutani, Luc Teyton, Wolfgang H. Fischer, Wendy L. Havran (August 2012).
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Kumanogoh A, Watanabe C, Lee I, Wang X, Shi W, Araki H, Hirata H, Iwahori K, Uchida J, Yasui T, Matsumoto M, Yoshida K, Yakura H, Pan C, Parnes JR, Kikutani H (November 2000).
1621:"Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses" 318: 217: 2133:
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages".
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Love CA, Harlos K, Mavaddat N, et al. (2003). "The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D".
3495: 909: 890: 140: 4357: 2681: 2657: 2357:"Semaphorin 4D/Plexin-B1 Induces Endothelial Cell Migration through the Activation of PYK2, Src, and the Phosphatidylinositol 3-Kinase-Akt Pathway" 1934:"Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis" 4088: 2478:"Expression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factor" 4076: 3854: 4140: 4135: 4081: 3861: 2642: 2603: 1497: 1479: 4754: 4749: 3594: 3520: 2650: 2209:"Semaphorin CD100 from activated T lymphocytes induces process extension collapse in oligodendrocytes and death of immature neural cells" 304: 51: 4723: 4623: 4618: 4613: 4608: 3535: 1580:"Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling" 1516:"Entrez Gene: SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D" 1260: 1253: 281: 4588: 1515: 3824: 1378:
it functions as an R-Ras GTPase-activating protein (GAP) and repels axon growth cones in both the mature central nervous system.
4759: 4392: 3886: 3572: 1466: 1445: 4716: 4031: 3567: 1462: 203: 178: 4528: 4000: 3995: 3940: 3674: 3123: 1441: 4222: 3945: 120: 3540: 317: 216: 4252: 2677: 1417: 310: 209: 1891:"Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates" 3118: 2596: 1969:"Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration" 4302: 3197: 2575: 954: 128: 2244:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" 4266: 2287:"CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival" 1717:"Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation" 935: 2047:"CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes" 3609: 3604: 3599: 3589: 2896: 2824: 1371: 2953: 2871: 2632:: THE LIGAND-BINDING FACE OF THE SEMAPHORINS REVEALED BY THE HIGH RESOLUTION CRYSTAL STRUCTURE OF SEMA4D 1813:"CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion" 4190: 3903: 2589: 2093: 1771: 192: 107: 4217: 4036: 2571: 1236: 1232: 1228: 1224: 1220: 1216: 1212: 1208: 1204: 1200: 1190: 1186: 1182: 1174: 1159: 1155: 1151: 1147: 1143: 1139: 1129: 1125: 1121: 1113: 1089: 1068: 1064: 1060: 1056: 1052: 1048: 1044: 1034: 1030: 1018: 3624: 3358: 2195: 2158: 1920: 1842: 1746: 1663:"The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function" 1405: 152: 2082:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1760:"Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation" 1178: 1117: 1093: 1026: 1022: 2552: 2521:
Shanks K, Nkyimbeng-Takwi EH, Smith EP, Lipsky MM, DeTolla LJ, Keegan AD, Chapoval SP (2013).
2509: 2464: 2421: 2386: 2343: 2308: 2273: 2230: 2187: 2150: 2121: 2068: 2033: 1990: 1955: 1912: 1877: 1834: 1799: 1738: 1692: 1642: 1601: 1560: 100: 44: 4700: 1531:"Sema4D/plexin-B1 activates GSK-3β through R-Ras GAP activity, inducing growth cone collapse" 4696: 4688: 4397: 4130: 4051: 3614: 2807: 2733: 2542: 2534: 2499: 2489: 2454: 2446: 2411: 2400:"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach" 2376: 2368: 2333: 2298: 2263: 2255: 2220: 2179: 2142: 2111: 2101: 2058: 2023: 2015: 1980: 1945: 1902: 1867: 1824: 1789: 1779: 1728: 1682: 1674: 1632: 1591: 1550: 1542: 555: 397: 328: 272: 227: 148: 4457: 2993: 2988: 2911: 2004:"The Plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding" 1363: 372: 2097: 1775: 27: 4242: 3664: 3175: 2978: 2547: 2522: 2504: 2477: 2459: 2434: 2381: 2356: 1687: 1662: 1555: 1530: 1390: 2268: 2243: 2116: 2081: 2028: 2003: 1907: 1890: 1596: 1579: 824: 819: 814: 809: 804: 799: 794: 789: 784: 779: 774: 769: 764: 759: 754: 749: 744: 739: 734: 729: 724: 719: 714: 709: 704: 699: 694: 689: 684: 668: 663: 658: 653: 648: 632: 627: 622: 617: 612: 607: 602: 597: 4743: 4212: 3669: 2760: 2372: 1794: 1759: 1359: 584: 2199: 2162: 1924: 1846: 1750: 4568: 3876: 3866: 3397: 3363: 390: 169: 132: 2538: 1829: 1812: 1678: 156: 4578: 4227: 4005: 3980: 3679: 3301: 3227: 2701: 2225: 2208: 1985: 1968: 1950: 1933: 1502:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1367: 2523:"Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation" 2416: 2399: 2338: 2321: 2303: 2286: 2063: 2046: 1733: 1716: 473: 111:, C9orf164, CD100, M-sema-G, SEMAJ, coll-4, semaphorin 4D, COLL4, A8, GR3, BB18 4508: 4232: 3913: 3654: 3530: 3163: 3158: 3153: 3008: 2792: 2450: 1619:
Ishida I, Kumanogoh A, Suzuki K, Akahani S, Noda K, Kikutani H (August 2003).
1340: 289: 186: 136: 1872: 1856:"Identification of a novel transmembrane semaphorin expressed on lymphocytes" 1855: 1784: 1546: 4347: 4342: 4337: 4327: 4322: 4317: 4312: 2494: 1637: 1620: 854: 730:
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
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Smith EP, Shanks K, Lipsky MM, DeTolla LJ, Keegan AD, Chapoval SP (2011).
1881: 1838: 1803: 1742: 1300: 1295: 4653: 4553: 4367: 4352: 3555: 3550: 3458: 3148: 1284: 999: 980: 4603: 4598: 4593: 4493: 4307: 4297: 4124: 4103: 4098: 4066: 3871: 3791: 3786: 3781: 3776: 3771: 3689: 3382: 3222: 3217: 3212: 3207: 3202: 2673: 2259: 2019: 1336: 966: 921: 77: 73: 4543: 4503: 4488: 4472: 4467: 4447: 4442: 4377: 4185: 4155: 4119: 4110: 3923: 3891: 3755: 3750: 3720: 3699: 3659: 3619: 3485: 3463: 3346: 3341: 3336: 3331: 3326: 3321: 3190: 3185: 3180: 3128: 3113: 2983: 2973: 2936: 2931: 2849: 2844: 1401: 1386: 1375: 1268: 876: 2183: 1393:, though much about this interaction is still under investigation. 4668: 4643: 4563: 4558: 4548: 4538: 4523: 4518: 4513: 4498: 4452: 4437: 4402: 4387: 4382: 4372: 4292: 4287: 4282: 4261: 4257: 4247: 4160: 4061: 4056: 4015: 3965: 3960: 3955: 3950: 3935: 3928: 3908: 3896: 3839: 3834: 3829: 3819: 3814: 3807: 3745: 3735: 3730: 3725: 3715: 3694: 3684: 3649: 3644: 3639: 3634: 3629: 3584: 3579: 3545: 3510: 3505: 3500: 3490: 3478: 3473: 3453: 3448: 3443: 3438: 3392: 3284: 3279: 3098: 3082: 3075: 3070: 3065: 3060: 3055: 3050: 3025: 3003: 2998: 2891: 2817: 2812: 2802: 2322:"Sema4D induces angiogenesis through Met recruitment by Plexin B1" 2146: 839: 835: 4663: 4658: 4648: 4638: 4633: 4628: 4583: 4573: 4533: 4462: 4432: 4427: 4422: 4417: 4412: 4407: 4362: 4332: 4237: 4205: 4200: 4180: 4170: 4165: 4150: 4145: 4046: 4041: 4010: 3990: 3985: 3975: 3970: 3849: 3802: 3762: 3417: 3412: 3407: 3402: 3387: 3378: 3373: 3368: 3353: 3311: 3306: 3296: 3291: 3274: 3269: 3264: 3259: 3254: 3249: 3244: 3239: 3234: 3170: 3143: 3138: 3133: 3108: 3103: 3040: 3035: 3030: 3020: 3015: 2968: 2963: 2958: 2948: 2943: 2926: 2921: 2916: 2906: 2901: 2886: 2881: 2876: 2866: 2861: 2856: 2839: 2834: 2829: 2780: 2748: 2743: 2738: 2721: 2716: 2711: 2706: 1397: 1382: 1347: 564: 124: 2646: 2585: 820:
negative regulation of axon extension involved in axon guidance
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positive regulation of phosphatidylinositol 3-kinase signaling
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Ito Y, Oinuma I, Katoh H, Kaibuchi K, Negishi M (July 2006).
2435:"Biology and function of neuroimmune semaphorins 4A and 4D" 2080:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
795:
negative regulation of transcription by RNA polymerase II
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Lewandrowski U, Moebius J, Walter U, Sickmann A (2006).
2045:
Granziero L, Circosta P, Scielzo C, et al. (2003).
1932:
Elhabazi A, Delaire S, Bensussan A, et al. (2001).
755:
negative regulation of peptidyl-tyrosine phosphorylation
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positive regulation of peptidyl-tyrosine phosphorylation
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Gerhard DS, Wagner L, Feingold EA, et al. (2004).
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Giraudon P, Vincent P, Vuaillat C, et al. (2004).
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Conrotto P, Valdembri D, Corso S, et al. (2005).
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Delaire S, Billard C, Tordjman R, et al. (2001).
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Tamagnone L, Artigiani S, Chen H, et al. (1999).
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Hall KT, Boumsell L, Schultze JL, et al. (1996).
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Deaglio S, Vaisitti T, Bergui L, et al. (2005).
1854:
Furuyama T, Inagaki S, Kosugi A, et al. (1997).
1811:
Herold C, Elhabazi A, Bismuth G, et al. (1997).
1715:
Bougeret C, Mansur IG, Dastot H, et al. (1992).
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negative regulation of alkaline phosphatase activity
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dentate gyrus of hippocampal formation granule cell
1458: 1456: 1454: 1437: 1435: 1433: 825:positive regulation of inhibitory synapse assembly 740:negative regulation of osteoblast differentiation 327: 226: 1463:GRCm38: Ensembl release 89: ENSMUSG00000021451 765:positive regulation of protein phosphorylation 4724: 2658: 2597: 8: 1442:GRCh38: Ensembl release 89: ENSG00000187764 745:positive regulation of collateral sprouting 4731: 4717: 2665: 2651: 2643: 2604: 2590: 2582: 1170: 1109: 1014: 850: 735:regulation of cell projection organization 580: 368: 267: 164: 62: 2682:list of human clusters of differentiation 2574:at the U.S. National Library of Medicine 2546: 2503: 2493: 2458: 2415: 2380: 2355:Basile JR, Afkhami T, Gutkind JS (2005). 2337: 2302: 2267: 2224: 2115: 2105: 2062: 2027: 1984: 1949: 1906: 1871: 1828: 1793: 1783: 1732: 1686: 1636: 1595: 1554: 603:transmembrane signaling receptor activity 2433:Nkyimbeng-Takwi EH, Chapoval SP (2011). 1343:family that in humans is encoded by the 785:ossification involved in bone maturation 690:negative regulation of apoptotic process 2619: 1429: 1408:to play a role in the healing process. 1400:damage repairs, SEMA4D interacts with 800:positive regulation of GTPase activity 17: 790:positive regulation of cell migration 654:integral component of plasma membrane 332: 293: 288: 231: 190: 185: 7: 4685: 4683: 715:negative regulation of cell adhesion 685:regulation of dendrite morphogenesis 770:semaphorin-plexin signaling pathway 725:positive regulation of axonogenesis 4703:. You can help Knowledge (XXG) by 1381:In the immune system, CD100 binds 1079: 990: 971: 945: 926: 900: 881: 700:multicellular organism development 550: 468: 406: 385: 14: 4687: 2622: 2373:10.1128/MCB.25.16.6889-6898.2005 2002:Vikis HG, Li W, Guan KL (2002). 554: 500:lumbar subsegment of spinal cord 442:inferior ganglion of vagus nerve 316: 309: 303: 280: 215: 208: 202: 177: 26: 1362:molecule which is secreted by 1358:Semaphorin 4D (Sema 4D) is an 649:integral component of membrane 565:More reference expression data 534:More reference expression data 1: 1908:10.1016/S0092-8674(00)80063-X 1597:10.1016/S1074-7613(00)00062-5 301: 200: 2539:10.1016/j.molimm.2013.05.228 2086:Proc. Natl. Acad. Sci. U.S.A 1830:10.4049/jimmunol.157.12.5262 1764:Proc. Natl. Acad. Sci. U.S.A 1679:10.1016/j.immuni.2012.05.026 4755:Clusters of differentiation 4750:Genes on human chromosome 9 2678:clusters of differentiation 2226:10.4049/jimmunol.172.2.1246 1986:10.4049/jimmunol.166.7.4348 1951:10.4049/jimmunol.166.7.4341 815:neural crest cell migration 628:signaling receptor activity 613:semaphorin receptor binding 4776: 4682: 2417:10.1074/mcp.M500324-MCP200 2339:10.1182/blood-2004-07-2885 2304:10.1182/blood-2004-10-3873 2064:10.1182/blood-2002-05-1339 1734:10.4049/jimmunol.148.2.318 1418:Cluster of differentiation 710:nervous system development 598:signaling receptor binding 2617: 2451:10.1007/s12026-010-8201-y 1498:"Mouse PubMed Reference:" 1480:"Human PubMed Reference:" 1299: 1294: 1290: 1283: 1267: 1248: 1197: 1136: 1105: 1086: 1041: 1010: 997: 993: 978: 974: 965: 952: 948: 933: 929: 920: 907: 903: 888: 884: 875: 860: 853: 849: 833: 623:identical protein binding 583: 579: 562: 553: 544: 531: 480: 471: 418: 409: 379: 371: 367: 350: 337: 300: 279: 270: 266: 249: 236: 199: 176: 167: 163: 118: 115: 105: 98: 93: 70: 65: 48: 43: 38: 34: 25: 20: 2576:Medical Subject Headings 1873:10.1074/jbc.271.52.33376 1785:10.1073/pnas.93.21.11780 1547:10.1038/sj.embor.7400737 1261:Chr 13: 51.69 – 51.79 Mb 750:regulation of cell shape 454:internal globus pallidus 2495:10.1186/1471-2172-12-30 633:chemorepellent activity 4760:Membrane protein stubs 4699:–related article is a 2107:10.1073/pnas.242603899 1372:central nervous system 1254:Chr 9: 89.36 – 89.5 Mb 492:mesenteric lymph nodes 2572:SEMA4D+protein,+human 2404:Mol. Cell. Proteomics 1638:10.1093/intimm/dxg098 705:leukocyte aggregation 295:Chromosome 13 (mouse) 760:cell differentiation 193:Chromosome 9 (human) 66:List of PDB id codes 39:Available structures 2098:2002PNAS...9916899M 1776:1996PNAS...9311780H 1406:Gamma delta T cells 810:negative chemotaxis 669:extracellular space 2260:10.1101/gr.2596504 2020:10.1101/gad.966402 1376:plexin B1 receptor 955:ENSMUSG00000021451 678:Biological process 642:Cellular component 618:neuropilin binding 591:Molecular function 508:tibiofemoral joint 157:SEMA4D - orthologs 4712: 4711: 4677: 4676: 2640: 2639: 2172:Nat. Struct. Biol 2092:(26): 16899–903. 1310: 1309: 1306: 1305: 1279: 1278: 1244: 1243: 1167: 1166: 1101: 1100: 1076: 1075: 1006: 1005: 987: 986: 961: 960: 942: 941: 916: 915: 897: 896: 845: 844: 575: 574: 571: 570: 540: 539: 527: 526: 465: 464: 363: 362: 262: 261: 89: 88: 85: 84: 49:Ortholog search: 4767: 4733: 4726: 4719: 4697:membrane protein 4691: 4684: 2667: 2660: 2653: 2644: 2626: 2606: 2599: 2592: 2583: 2560: 2550: 2517: 2507: 2497: 2472: 2462: 2429: 2419: 2394: 2384: 2351: 2341: 2316: 2306: 2281: 2271: 2238: 2228: 2203: 2166: 2129: 2119: 2109: 2076: 2066: 2041: 2031: 1998: 1988: 1963: 1953: 1928: 1910: 1885: 1875: 1866:(52): 33376–81. 1850: 1832: 1807: 1797: 1787: 1754: 1736: 1701: 1700: 1690: 1657: 1651: 1650: 1640: 1616: 1610: 1609: 1599: 1575: 1569: 1568: 1558: 1526: 1520: 1519: 1512: 1506: 1505: 1494: 1488: 1487: 1476: 1470: 1460: 1449: 1439: 1370:collapse in the 1364:oligodendrocytes 1319:) also known as 1292: 1291: 1263: 1256: 1239: 1171: 1162: 1110: 1106:RefSeq (protein) 1096: 1080: 1071: 1015: 991: 972: 946: 927: 901: 882: 851: 581: 567: 558: 551: 536: 476: 474:Top expressed in 469: 458:substantia nigra 414: 412:Top expressed in 407: 386: 369: 359: 346: 335: 320: 313: 307: 296: 284: 268: 258: 245: 234: 219: 212: 206: 195: 181: 165: 159: 110: 103: 80: 63: 57: 36: 35: 30: 18: 4775: 4774: 4770: 4769: 4768: 4766: 4765: 4764: 4740: 4739: 4738: 4737: 4680: 4678: 4673: 4477: 4271: 4020: 3704: 3427: 3087: 2685: 2671: 2641: 2636: 2633: 2627: 2613: 2610: 2568: 2563: 2520: 2475: 2432: 2397: 2367:(16): 6889–98. 2361:Mol. Cell. Biol 2354: 2319: 2284: 2254:(10B): 2121–7. 2241: 2206: 2169: 2132: 2079: 2044: 2001: 1966: 1931: 1888: 1853: 1810: 1770:(21): 11780–5. 1757: 1714: 1710: 1708:Further reading 1705: 1704: 1659: 1658: 1654: 1618: 1617: 1613: 1577: 1576: 1572: 1528: 1527: 1523: 1514: 1513: 1509: 1496: 1495: 1491: 1478: 1477: 1473: 1461: 1452: 1440: 1431: 1426: 1414: 1391:dendritic cells 1356: 1327:ifferentiation 1301:View/Edit Mouse 1296:View/Edit Human 1259: 1252: 1249:Location (UCSC) 1235: 1231: 1227: 1223: 1219: 1215: 1211: 1207: 1203: 1199: 1193: 1189: 1185: 1181: 1177: 1158: 1154: 1150: 1146: 1142: 1138: 1132: 1128: 1124: 1120: 1116: 1092: 1088: 1067: 1063: 1059: 1055: 1051: 1047: 1043: 1037: 1033: 1029: 1025: 1021: 936:ENSG00000187764 829: 780:immune response 673: 664:plasma membrane 637: 608:protein binding 563: 532: 523: 518: 514: 510: 506: 502: 498: 494: 490: 488:muscle of thigh 486: 472: 461: 456: 452: 450:muscle of thigh 448: 444: 440: 436: 432: 430:corpus callosum 428: 424: 410: 354: 341: 333: 323: 322: 321: 314: 294: 271:Gene location ( 253: 240: 232: 222: 221: 220: 213: 191: 168:Gene location ( 119: 106: 99: 72: 50: 12: 11: 5: 4773: 4771: 4763: 4762: 4757: 4752: 4742: 4741: 4736: 4735: 4728: 4721: 4713: 4710: 4709: 4692: 4675: 4674: 4672: 4671: 4666: 4661: 4656: 4651: 4646: 4641: 4636: 4631: 4626: 4621: 4616: 4611: 4606: 4601: 4596: 4591: 4586: 4581: 4576: 4571: 4566: 4561: 4556: 4551: 4546: 4541: 4536: 4531: 4526: 4521: 4516: 4511: 4506: 4501: 4496: 4491: 4485: 4483: 4479: 4478: 4476: 4475: 4470: 4465: 4460: 4455: 4450: 4445: 4440: 4435: 4430: 4425: 4420: 4415: 4410: 4405: 4400: 4395: 4390: 4385: 4380: 4375: 4370: 4365: 4360: 4355: 4350: 4345: 4340: 4335: 4330: 4325: 4320: 4315: 4310: 4305: 4300: 4295: 4290: 4285: 4279: 4277: 4273: 4272: 4270: 4269: 4264: 4255: 4250: 4245: 4240: 4235: 4230: 4225: 4220: 4215: 4210: 4209: 4208: 4203: 4193: 4188: 4183: 4178: 4173: 4168: 4163: 4158: 4153: 4148: 4143: 4138: 4133: 4128: 4122: 4113: 4108: 4107: 4106: 4101: 4091: 4086: 4085: 4084: 4079: 4069: 4064: 4059: 4054: 4049: 4044: 4039: 4034: 4028: 4026: 4022: 4021: 4019: 4018: 4013: 4008: 4003: 3998: 3993: 3988: 3983: 3978: 3973: 3968: 3963: 3958: 3953: 3948: 3943: 3938: 3933: 3932: 3931: 3926: 3916: 3911: 3906: 3901: 3900: 3899: 3894: 3889: 3879: 3874: 3869: 3864: 3859: 3858: 3857: 3852: 3842: 3837: 3832: 3827: 3822: 3817: 3812: 3811: 3810: 3805: 3795: 3789: 3784: 3779: 3774: 3765: 3760: 3759: 3758: 3753: 3748: 3738: 3733: 3728: 3723: 3718: 3712: 3710: 3706: 3705: 3703: 3702: 3697: 3692: 3687: 3682: 3677: 3672: 3667: 3662: 3657: 3652: 3647: 3642: 3637: 3632: 3627: 3622: 3617: 3612: 3607: 3602: 3597: 3592: 3587: 3582: 3577: 3576: 3575: 3570: 3560: 3559: 3558: 3553: 3543: 3538: 3533: 3528: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3483: 3482: 3481: 3476: 3466: 3461: 3456: 3451: 3446: 3441: 3435: 3433: 3429: 3428: 3426: 3425: 3420: 3415: 3410: 3405: 3400: 3395: 3390: 3385: 3376: 3371: 3366: 3361: 3356: 3351: 3350: 3349: 3344: 3339: 3334: 3329: 3324: 3314: 3309: 3304: 3299: 3294: 3289: 3288: 3287: 3282: 3272: 3267: 3262: 3257: 3252: 3247: 3242: 3237: 3232: 3231: 3230: 3225: 3220: 3215: 3210: 3205: 3195: 3194: 3193: 3188: 3183: 3173: 3168: 3167: 3166: 3161: 3156: 3146: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3095: 3093: 3089: 3088: 3086: 3085: 3080: 3079: 3078: 3073: 3068: 3063: 3058: 3053: 3043: 3038: 3033: 3028: 3023: 3018: 3013: 3012: 3011: 3006: 3001: 2996: 2986: 2981: 2976: 2971: 2966: 2961: 2956: 2951: 2946: 2941: 2940: 2939: 2934: 2924: 2919: 2914: 2909: 2904: 2899: 2894: 2889: 2884: 2879: 2874: 2869: 2864: 2859: 2854: 2853: 2852: 2847: 2837: 2832: 2827: 2822: 2821: 2820: 2815: 2810: 2805: 2795: 2790: 2785: 2784: 2783: 2773: 2768: 2763: 2758: 2753: 2752: 2751: 2746: 2741: 2731: 2726: 2725: 2724: 2719: 2714: 2709: 2704: 2693: 2691: 2687: 2686: 2672: 2670: 2669: 2662: 2655: 2647: 2638: 2637: 2635: 2634: 2628: 2621: 2618: 2615: 2614: 2611: 2609: 2608: 2601: 2594: 2586: 2580: 2579: 2567: 2566:External links 2564: 2562: 2561: 2518: 2473: 2430: 2395: 2352: 2332:(11): 4321–9. 2317: 2297:(8): 3042–50. 2282: 2239: 2219:(2): 1246–55. 2204: 2184:10.1038/nsb977 2167: 2130: 2077: 2042: 1999: 1979:(7): 4348–54. 1964: 1929: 1886: 1851: 1823:(12): 5262–8. 1808: 1755: 1711: 1709: 1706: 1703: 1702: 1652: 1631:(8): 1027–34. 1611: 1570: 1521: 1507: 1489: 1471: 1450: 1428: 1427: 1425: 1422: 1421: 1420: 1413: 1410: 1355: 1352: 1308: 1307: 1304: 1303: 1298: 1288: 1287: 1281: 1280: 1277: 1276: 1274: 1272: 1265: 1264: 1257: 1250: 1246: 1245: 1242: 1241: 1195: 1194: 1168: 1165: 1164: 1134: 1133: 1107: 1103: 1102: 1099: 1098: 1084: 1083: 1077: 1074: 1073: 1039: 1038: 1012: 1008: 1007: 1004: 1003: 995: 994: 988: 985: 984: 976: 975: 969: 963: 962: 959: 958: 950: 949: 943: 940: 939: 931: 930: 924: 918: 917: 914: 913: 905: 904: 898: 895: 894: 886: 885: 879: 873: 872: 867: 862: 858: 857: 847: 846: 843: 842: 831: 830: 828: 827: 822: 817: 812: 807: 802: 797: 792: 787: 782: 777: 772: 767: 762: 757: 752: 747: 742: 737: 732: 727: 722: 717: 712: 707: 702: 697: 692: 687: 681: 679: 675: 674: 672: 671: 666: 661: 656: 651: 645: 643: 639: 638: 636: 635: 630: 625: 620: 615: 610: 605: 600: 594: 592: 588: 587: 577: 576: 573: 572: 569: 568: 560: 559: 548: 542: 541: 538: 537: 529: 528: 525: 524: 522: 521: 517: 513: 509: 505: 501: 497: 493: 489: 485: 481: 478: 477: 466: 463: 462: 460: 459: 455: 451: 447: 443: 439: 435: 431: 427: 423: 419: 416: 415: 403: 402: 394: 383: 377: 376: 373:RNA expression 365: 364: 361: 360: 352: 348: 347: 339: 336: 331: 325: 324: 315: 308: 302: 298: 297: 292: 286: 285: 277: 276: 264: 263: 260: 259: 251: 247: 246: 238: 235: 230: 224: 223: 214: 207: 201: 197: 196: 189: 183: 182: 174: 173: 161: 160: 117: 113: 112: 104: 96: 95: 91: 90: 87: 86: 83: 82: 68: 67: 59: 58: 47: 41: 40: 32: 31: 23: 22: 13: 10: 9: 6: 4: 3: 2: 4772: 4761: 4758: 4756: 4753: 4751: 4748: 4747: 4745: 4734: 4729: 4727: 4722: 4720: 4715: 4714: 4708: 4706: 4702: 4698: 4693: 4690: 4686: 4681: 4670: 4667: 4665: 4662: 4660: 4657: 4655: 4652: 4650: 4647: 4645: 4642: 4640: 4637: 4635: 4632: 4630: 4627: 4625: 4622: 4620: 4617: 4615: 4612: 4610: 4607: 4605: 4602: 4600: 4597: 4595: 4592: 4590: 4587: 4585: 4582: 4580: 4577: 4575: 4572: 4570: 4567: 4565: 4562: 4560: 4557: 4555: 4552: 4550: 4547: 4545: 4542: 4540: 4537: 4535: 4532: 4530: 4527: 4525: 4522: 4520: 4517: 4515: 4512: 4510: 4507: 4505: 4502: 4500: 4497: 4495: 4492: 4490: 4487: 4486: 4484: 4480: 4474: 4471: 4469: 4466: 4464: 4461: 4459: 4456: 4454: 4451: 4449: 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4401: 4399: 4396: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4376: 4374: 4371: 4369: 4366: 4364: 4361: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4319: 4316: 4314: 4311: 4309: 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4286: 4284: 4281: 4280: 4278: 4274: 4268: 4265: 4263: 4259: 4256: 4254: 4251: 4249: 4246: 4244: 4241: 4239: 4236: 4234: 4231: 4229: 4226: 4224: 4221: 4219: 4216: 4214: 4211: 4207: 4204: 4202: 4199: 4198: 4197: 4194: 4192: 4189: 4187: 4184: 4182: 4179: 4177: 4174: 4172: 4169: 4167: 4164: 4162: 4159: 4157: 4154: 4152: 4149: 4147: 4144: 4142: 4139: 4137: 4134: 4132: 4129: 4126: 4123: 4121: 4117: 4114: 4112: 4109: 4105: 4102: 4100: 4097: 4096: 4095: 4092: 4090: 4087: 4083: 4080: 4078: 4075: 4074: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4048: 4045: 4043: 4040: 4038: 4035: 4033: 4030: 4029: 4027: 4023: 4017: 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3944: 3942: 3939: 3937: 3934: 3930: 3927: 3925: 3922: 3921: 3920: 3917: 3915: 3912: 3910: 3907: 3905: 3902: 3898: 3895: 3893: 3890: 3888: 3885: 3884: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3863: 3860: 3856: 3853: 3851: 3848: 3847: 3846: 3843: 3841: 3838: 3836: 3833: 3831: 3828: 3826: 3823: 3821: 3818: 3816: 3813: 3809: 3806: 3804: 3801: 3800: 3799: 3796: 3793: 3790: 3788: 3785: 3783: 3780: 3778: 3775: 3773: 3769: 3766: 3764: 3761: 3757: 3754: 3752: 3749: 3747: 3744: 3743: 3742: 3739: 3737: 3734: 3732: 3729: 3727: 3724: 3722: 3719: 3717: 3714: 3713: 3711: 3707: 3701: 3698: 3696: 3693: 3691: 3688: 3686: 3683: 3681: 3678: 3676: 3673: 3671: 3668: 3666: 3663: 3661: 3658: 3656: 3653: 3651: 3648: 3646: 3643: 3641: 3638: 3636: 3633: 3631: 3628: 3626: 3623: 3621: 3618: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3586: 3583: 3581: 3578: 3574: 3571: 3569: 3566: 3565: 3564: 3561: 3557: 3554: 3552: 3549: 3548: 3547: 3544: 3542: 3539: 3537: 3534: 3532: 3529: 3527: 3524: 3522: 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3480: 3477: 3475: 3472: 3471: 3470: 3467: 3465: 3462: 3460: 3457: 3455: 3452: 3450: 3447: 3445: 3442: 3440: 3437: 3436: 3434: 3430: 3424: 3421: 3419: 3416: 3414: 3411: 3409: 3406: 3404: 3401: 3399: 3396: 3394: 3391: 3389: 3386: 3384: 3380: 3377: 3375: 3372: 3370: 3367: 3365: 3362: 3360: 3357: 3355: 3352: 3348: 3345: 3343: 3340: 3338: 3335: 3333: 3330: 3328: 3325: 3323: 3320: 3319: 3318: 3315: 3313: 3310: 3308: 3305: 3303: 3300: 3298: 3295: 3293: 3290: 3286: 3283: 3281: 3278: 3277: 3276: 3273: 3271: 3268: 3266: 3263: 3261: 3258: 3256: 3253: 3251: 3248: 3246: 3243: 3241: 3238: 3236: 3233: 3229: 3226: 3224: 3221: 3219: 3216: 3214: 3211: 3209: 3206: 3204: 3201: 3200: 3199: 3196: 3192: 3189: 3187: 3184: 3182: 3179: 3178: 3177: 3174: 3172: 3169: 3165: 3162: 3160: 3157: 3155: 3152: 3151: 3150: 3147: 3145: 3142: 3140: 3137: 3135: 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3096: 3094: 3090: 3084: 3081: 3077: 3074: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3048: 3047: 3044: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3024: 3022: 3019: 3017: 3014: 3010: 3007: 3005: 3002: 3000: 2997: 2995: 2992: 2991: 2990: 2987: 2985: 2982: 2980: 2977: 2975: 2972: 2970: 2967: 2965: 2962: 2960: 2957: 2955: 2952: 2950: 2947: 2945: 2942: 2938: 2935: 2933: 2930: 2929: 2928: 2925: 2923: 2920: 2918: 2915: 2913: 2910: 2908: 2905: 2903: 2900: 2898: 2895: 2893: 2890: 2888: 2885: 2883: 2880: 2878: 2875: 2873: 2870: 2868: 2865: 2863: 2860: 2858: 2855: 2851: 2848: 2846: 2843: 2842: 2841: 2838: 2836: 2833: 2831: 2828: 2826: 2823: 2819: 2816: 2814: 2811: 2809: 2806: 2804: 2801: 2800: 2799: 2796: 2794: 2791: 2789: 2786: 2782: 2779: 2778: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2757: 2754: 2750: 2747: 2745: 2742: 2740: 2737: 2736: 2735: 2732: 2730: 2727: 2723: 2720: 2718: 2715: 2713: 2710: 2708: 2705: 2703: 2700: 2699: 2698: 2695: 2694: 2692: 2688: 2683: 2679: 2675: 2668: 2663: 2661: 2656: 2654: 2649: 2648: 2645: 2631: 2625: 2620: 2616: 2607: 2602: 2600: 2595: 2593: 2588: 2587: 2584: 2577: 2573: 2570: 2569: 2565: 2558: 2554: 2549: 2544: 2540: 2536: 2532: 2528: 2524: 2519: 2515: 2511: 2506: 2501: 2496: 2491: 2487: 2483: 2479: 2474: 2470: 2466: 2461: 2456: 2452: 2448: 2444: 2440: 2436: 2431: 2427: 2423: 2418: 2413: 2410:(2): 226–33. 2409: 2405: 2401: 2396: 2392: 2388: 2383: 2378: 2374: 2370: 2366: 2362: 2358: 2353: 2349: 2345: 2340: 2335: 2331: 2327: 2323: 2318: 2314: 2310: 2305: 2300: 2296: 2292: 2288: 2283: 2279: 2275: 2270: 2265: 2261: 2257: 2253: 2249: 2245: 2240: 2236: 2232: 2227: 2222: 2218: 2214: 2210: 2205: 2201: 2197: 2193: 2189: 2185: 2181: 2178:(10): 843–8. 2177: 2173: 2168: 2164: 2160: 2156: 2152: 2148: 2147:10.1038/nm822 2144: 2140: 2136: 2131: 2127: 2123: 2118: 2113: 2108: 2103: 2099: 2095: 2091: 2087: 2083: 2078: 2074: 2070: 2065: 2060: 2057:(5): 1962–9. 2056: 2052: 2048: 2043: 2039: 2035: 2030: 2025: 2021: 2017: 2014:(7): 836–45. 2013: 2009: 2005: 2000: 1996: 1992: 1987: 1982: 1978: 1974: 1970: 1965: 1961: 1957: 1952: 1947: 1944:(7): 4341–7. 1943: 1939: 1935: 1930: 1926: 1922: 1918: 1914: 1909: 1904: 1900: 1896: 1892: 1887: 1883: 1879: 1874: 1869: 1865: 1861: 1860:J. Biol. Chem 1857: 1852: 1848: 1844: 1840: 1836: 1831: 1826: 1822: 1818: 1814: 1809: 1805: 1801: 1796: 1791: 1786: 1781: 1777: 1773: 1769: 1765: 1761: 1756: 1752: 1748: 1744: 1740: 1735: 1730: 1727:(2): 318–23. 1726: 1722: 1718: 1713: 1712: 1707: 1698: 1694: 1689: 1684: 1680: 1676: 1673:(2): 314–25. 1672: 1668: 1664: 1656: 1653: 1648: 1644: 1639: 1634: 1630: 1626: 1622: 1615: 1612: 1607: 1603: 1598: 1593: 1590:(5): 621–31. 1589: 1585: 1581: 1574: 1571: 1566: 1562: 1557: 1552: 1548: 1544: 1540: 1536: 1532: 1525: 1522: 1517: 1511: 1508: 1503: 1499: 1493: 1490: 1485: 1481: 1475: 1472: 1468: 1464: 1459: 1457: 1455: 1451: 1447: 1443: 1438: 1436: 1434: 1430: 1423: 1419: 1416: 1415: 1411: 1409: 1407: 1403: 1399: 1394: 1392: 1388: 1384: 1379: 1377: 1374:. By binding 1373: 1369: 1365: 1361: 1360:axon guidance 1353: 1351: 1349: 1346: 1342: 1338: 1334: 1330: 1326: 1322: 1318: 1314: 1313:Semaphorin-4D 1302: 1297: 1293: 1289: 1286: 1282: 1275: 1273: 1270: 1266: 1262: 1258: 1255: 1251: 1247: 1240: 1238: 1234: 1230: 1226: 1222: 1218: 1214: 1210: 1206: 1202: 1196: 1192: 1188: 1184: 1180: 1176: 1172: 1169: 1163: 1161: 1157: 1153: 1149: 1145: 1141: 1135: 1131: 1127: 1123: 1119: 1115: 1111: 1108: 1104: 1097: 1095: 1091: 1085: 1081: 1078: 1072: 1070: 1066: 1062: 1058: 1054: 1050: 1046: 1040: 1036: 1032: 1028: 1024: 1020: 1016: 1013: 1011:RefSeq (mRNA) 1009: 1002: 1001: 996: 992: 989: 983: 982: 977: 973: 970: 968: 964: 957: 956: 951: 947: 944: 938: 937: 932: 928: 925: 923: 919: 912: 911: 906: 902: 899: 893: 892: 887: 883: 880: 878: 874: 871: 868: 866: 863: 859: 856: 852: 848: 841: 837: 832: 826: 823: 821: 818: 816: 813: 811: 808: 806: 803: 801: 798: 796: 793: 791: 788: 786: 783: 781: 778: 776: 775:cell adhesion 773: 771: 768: 766: 763: 761: 758: 756: 753: 751: 748: 746: 743: 741: 738: 736: 733: 731: 728: 726: 723: 721: 718: 716: 713: 711: 708: 706: 703: 701: 698: 696: 693: 691: 688: 686: 683: 682: 680: 677: 676: 670: 667: 665: 662: 660: 657: 655: 652: 650: 647: 646: 644: 641: 640: 634: 631: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 599: 596: 595: 593: 590: 589: 586: 585:Gene ontology 582: 578: 566: 561: 557: 552: 549: 547: 543: 535: 530: 519: 515: 511: 507: 503: 499: 495: 491: 487: 483: 482: 479: 475: 470: 467: 457: 453: 449: 445: 441: 437: 433: 429: 425: 421: 420: 417: 413: 408: 405: 404: 401: 399: 395: 393: 392: 388: 387: 384: 382: 378: 374: 370: 366: 358: 353: 349: 345: 340: 334:13|13 A5 330: 326: 319: 312: 306: 299: 291: 287: 283: 278: 274: 269: 265: 257: 252: 248: 244: 239: 229: 225: 218: 211: 205: 198: 194: 188: 184: 180: 175: 171: 166: 162: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 114: 109: 102: 97: 92: 81: 79: 75: 69: 64: 61: 60: 56: 53: 46: 42: 37: 33: 29: 24: 19: 16: 4705:expanding it 4694: 4679: 4195: 4115: 4093: 4071: 3918: 3881: 3844: 3797: 3767: 3740: 3562: 3468: 3422: 3316: 3045: 2797: 2629: 2533:(4): 480–7. 2530: 2527:Mol. Immunol 2526: 2485: 2481: 2445:(1): 10–21. 2442: 2439:Immunol. Res 2438: 2407: 2403: 2364: 2360: 2329: 2325: 2294: 2290: 2251: 2247: 2216: 2212: 2175: 2171: 2141:(2): 191–7. 2138: 2134: 2089: 2085: 2054: 2050: 2011: 2007: 1976: 1972: 1941: 1937: 1901:(1): 71–80. 1898: 1894: 1863: 1859: 1820: 1816: 1767: 1763: 1724: 1720: 1670: 1666: 1655: 1628: 1625:Int. Immunol 1624: 1614: 1587: 1583: 1573: 1541:(7): 704–9. 1538: 1535:EMBO Reports 1534: 1524: 1510: 1501: 1492: 1483: 1474: 1395: 1385:to activate 1380: 1366:and induces 1357: 1344: 1332: 1328: 1324: 1320: 1316: 1312: 1311: 1237:NP_001365254 1233:NP_001365250 1229:NP_001365245 1225:NP_001365244 1221:NP_001365253 1217:NP_001365252 1213:NP_001365251 1209:NP_001365249 1205:NP_001365248 1201:NP_001365247 1198: 1191:NP_001365246 1187:NP_001365243 1183:NP_001365242 1175:NP_001268809 1160:NP_001358131 1156:NP_001358130 1152:NP_001358129 1148:NP_001358128 1144:NP_001358127 1140:NP_001358126 1137: 1130:NP_001358125 1126:NP_001358124 1122:NP_001358123 1114:NP_001135759 1090:NM_001281880 1087: 1069:NM_001371202 1065:NM_001371201 1061:NM_001371200 1057:NM_001371199 1053:NM_001371198 1049:NM_001371197 1045:NM_001371196 1042: 1035:NM_001371195 1031:NM_001371194 1019:NM_001142287 998: 979: 953: 934: 908: 889: 869: 864: 504:cumulus cell 396: 389: 116:External IDs 71: 15: 2612:PDB gallery 2482:BMC Immunol 1368:growth cone 484:granulocyte 426:granulocyte 355:51,793,747 342:51,685,529 254:89,498,130 241:89,360,787 94:Identifiers 4744:Categories 2680:(see also 2248:Genome Res 2213:J. Immunol 1973:J. Immunol 1938:J. Immunol 1817:J. Immunol 1721:J. Immunol 1469:, May 2017 1448:, May 2017 1424:References 1341:semaphorin 1323:luster of 446:lymph node 422:C1 segment 400:(ortholog) 137:HomoloGene 2008:Genes Dev 1402:Plexin B2 1179:NP_038688 1118:NP_006369 1094:NM_013660 1027:NM_182635 1023:NM_006378 855:Orthologs 145:GeneCards 2674:Proteins 2557:23911404 2514:21595947 2469:21203905 2426:16263699 2391:16055703 2348:15632204 2313:15613544 2278:15489334 2235:14707103 2200:24468463 2192:12958590 2163:26145639 2155:12539042 2135:Nat. Med 2126:12477932 2073:12406905 2038:11937491 1995:11254688 1960:11254687 1925:17386412 1917:10520995 1847:36341775 1751:29224711 1697:22902232 1667:Immunity 1647:12882840 1606:11114375 1584:Immunity 1565:16799460 1465:– 1444:– 1412:See also 1354:Function 1335:), is a 1285:Wikidata 834:Sources: 659:membrane 438:monocyte 4482:301–350 4276:251–300 4228:CD240CE 4025:201–250 3709:151–200 3432:101–150 2548:3783523 2505:3118960 2460:3366695 2382:1190270 2094:Bibcode 1882:8969198 1839:8955171 1804:8876214 1772:Bibcode 1743:1530858 1688:3430606 1556:1500830 1467:Ensembl 1446:Ensembl 1396:During 1387:B cells 1339:of the 1337:protein 967:UniProt 922:Ensembl 861:Species 840:QuickGO 375:pattern 101:Aliases 4489:CD300A 4448:CDw293 4233:CD240D 4094:CD213a 4072:CDw210 4037:CD202b 4011:CDw199 4006:CDw198 3660:CD140b 3092:51–100 2578:(MeSH) 2555:  2545:  2512:  2502:  2488:: 30. 2467:  2457:  2424:  2389:  2379:  2346:  2311:  2276:  2269:528928 2266:  2233:  2198:  2190:  2161:  2153:  2124:  2117:139241 2114:  2071:  2036:  2029:186329 2026:  1993:  1958:  1923:  1915:  1880:  1845:  1837:  1802:  1792:  1749:  1741:  1695:  1685:  1645:  1604:  1563:  1553:  1345:SEMA4D 1317:SEMA4D 1271:search 1269:PubMed 1000:O09126 981:Q92854 877:Entrez 546:BioGPS 520:spleen 496:thymus 233:9q22.2 149:SEMA4D 133:109244 125:601866 108:SEMA4D 21:SEMA4D 4695:This 4669:CD350 4664:CD349 4659:CD344 4654:CD340 4649:CD339 4644:CD338 4639:CD337 4634:CD336 4629:CD335 4624:CD334 4619:CD333 4614:CD332 4609:CD331 4604:CD329 4599:CD328 4594:CD327 4589:CD326 4584:CD325 4579:CD324 4574:CD322 4569:CD321 4564:CD320 4559:CD318 4554:CD317 4549:CD316 4544:CD315 4539:CD314 4534:CD312 4529:CD309 4524:CD307 4519:CD306 4514:CD305 4509:CD304 4504:CD303 4499:CD302 4494:CD301 4473:CD299 4468:CD298 4463:CD297 4458:CD295 4453:CD294 4443:CD292 4438:CD290 4433:CD289 4428:CD288 4423:CD286 4418:CD284 4413:CD283 4408:CD282 4403:CD281 4398:CD280 4393:CD279 4388:CD278 4383:CD276 4378:CD275 4373:CD274 4368:CD273 4363:CD272 4358:CD271 4353:CD269 4348:CD268 4343:CD267 4338:CD266 4333:CD265 4328:CD264 4323:CD263 4318:CD262 4313:CD261 4308:CD258 4303:CD257 4298:CD256 4293:CD254 4288:CD253 4283:CD252 4267:CD249 4262:CD248 4258:CD247 4253:CD246 4248:CD244 4243:CD243 4238:CD241 4223:CD239 4218:CD238 4213:CD236 4196:CD235 4191:CD234 4186:CD233 4181:CD230 4176:CD229 4171:CD228 4166:CD227 4161:CD226 4156:CD225 4151:CD224 4146:CD223 4141:CD222 4136:CD221 4131:CD220 4116:CD218 4111:CD217 4089:CD212 4067:CD209 4062:CD208 4057:CD207 4052:CD206 4047:CD205 4042:CD204 4032:CD201 4016:CD200 4001:CD197 3996:CD196 3991:CD195 3986:CD194 3981:CD193 3976:CD192 3971:CD191 3966:CD186 3961:CD185 3956:CD184 3951:CD183 3946:CD182 3941:CD181 3936:CD180 3919:CD179 3914:CD178 3909:CD177 3904:CD174 3882:CD172 3877:CD171 3872:CD170 3867:CD169 3862:CD168 3845:CD167 3840:CD166 3835:CD164 3830:CD163 3825:CD162 3820:CD161 3815:CD160 3798:CD159 3768:CD158 3763:CD157 3741:CD156 3736:CD155 3731:CD154 3726:CD153 3721:CD152 3716:CD151 3700:CD150 3695:CD148 3690:CD147 3685:CD146 3680:CD144 3675:CD143 3670:CD142 3665:CD141 3655:CD138 3650:CD137 3645:CD136 3640:CD135 3635:CD134 3630:CD133 3625:CD132 3620:CD131 3615:CD130 3610:CD129 3605:CD127 3600:CD126 3595:CD125 3590:CD124 3585:CD123 3580:CD122 3563:CD121 3546:CD120 3541:CD119 3536:CD118 3531:CD117 3526:CD116 3521:CD115 3516:CD114 3511:CD113 3506:CD112 3501:CD111 3496:CD110 3491:CD109 3486:CD108 3469:CD107 3464:CD106 3459:CD105 3454:CD104 3449:CD103 3444:CD102 3439:CD101 3423:CD100 2326:Blood 2291:Blood 2196:S2CID 2159:S2CID 2051:Blood 1921:S2CID 1843:S2CID 1795:38135 1747:S2CID 1333:CD100 910:20354 891:10507 870:Mouse 865:Human 836:Amigo 512:blood 434:blood 398:Mouse 391:Human 338:Start 273:Mouse 237:Start 170:Human 141:21282 4701:stub 3418:CD99 3413:CD98 3408:CD97 3403:CD96 3398:CD95 3393:CD94 3388:CD93 3383:CD92 3379:CD91 3374:CD90 3369:CD89 3364:CD88 3359:CD87 3354:CD86 3317:CD85 3312:CD84 3307:CD83 3302:CD82 3297:CD81 3292:CD80 3275:CD79 3270:CD78 3265:CD74 3260:CD73 3255:CD72 3250:CD71 3245:CD70 3240:CD69 3235:CD68 3198:CD66 3176:CD64 3171:CD63 3149:CD62 3144:CD61 3139:CD59 3134:CD58 3129:CD57 3124:CD56 3119:CD55 3114:CD54 3109:CD53 3104:CD52 3099:CD51 3083:CD50 3046:CD49 3041:CD48 3036:CD47 3031:CD46 3026:CD45 3021:CD44 3016:CD43 2989:CD42 2984:CD41 2979:CD40 2974:CD39 2969:CD38 2964:CD37 2959:CD36 2954:CD35 2949:CD34 2944:CD33 2927:CD32 2922:CD31 2917:CD30 2912:CD29 2907:CD28 2902:CD27 2897:CD26 2892:CD25 2887:CD24 2882:CD23 2877:CD22 2872:CD21 2867:CD20 2862:CD19 2857:CD18 2840:CD16 2835:CD15 2830:CD14 2825:CD13 2798:CD11 2793:CD10 2690:1–50 2630:1olz 2553:PMID 2510:PMID 2465:PMID 2422:PMID 2387:PMID 2344:PMID 2309:PMID 2274:PMID 2231:PMID 2188:PMID 2151:PMID 2122:PMID 2069:PMID 2034:PMID 1991:PMID 1956:PMID 1913:PMID 1895:Cell 1878:PMID 1835:PMID 1800:PMID 1739:PMID 1693:PMID 1643:PMID 1602:PMID 1561:PMID 1398:skin 1389:and 1383:CD72 1348:gene 381:Bgee 329:Band 290:Chr. 228:Band 187:Chr. 121:OMIM 78:3OL2 74:1OLZ 55:RCSB 52:PDBe 2788:CD9 2776:CD8 2771:CD7 2766:CD6 2761:CD5 2756:CD4 2734:CD3 2729:CD2 2702:a-c 2697:CD1 2543:PMC 2535:doi 2500:PMC 2490:doi 2455:PMC 2447:doi 2412:doi 2377:PMC 2369:doi 2334:doi 2330:105 2299:doi 2295:105 2264:PMC 2256:doi 2221:doi 2217:172 2180:doi 2143:doi 2112:PMC 2102:doi 2059:doi 2055:101 2024:PMC 2016:doi 1981:doi 1977:166 1946:doi 1942:166 1903:doi 1868:doi 1864:271 1825:doi 1821:157 1790:PMC 1780:doi 1729:doi 1725:148 1683:PMC 1675:doi 1633:doi 1592:doi 1551:PMC 1543:doi 1404:on 1329:100 351:End 250:End 153:OMA 129:MGI 45:PDB 4746:: 4260:- 3381:- 2722:1E 2717:1D 2712:1B 2707:1A 2676:: 2551:. 2541:. 2531:56 2529:. 2525:. 2508:. 2498:. 2486:12 2484:. 2480:. 2463:. 2453:. 2443:50 2441:. 2437:. 2420:. 2406:. 2402:. 2385:. 2375:. 2365:25 2363:. 2359:. 2342:. 2328:. 2324:. 2307:. 2293:. 2289:. 2272:. 2262:. 2252:14 2250:. 2246:. 2229:. 2215:. 2211:. 2194:. 2186:. 2176:10 2174:. 2157:. 2149:. 2137:. 2120:. 2110:. 2100:. 2090:99 2088:. 2084:. 2067:. 2053:. 2049:. 2032:. 2022:. 2012:16 2010:. 2006:. 1989:. 1975:. 1971:. 1954:. 1940:. 1936:. 1919:. 1911:. 1899:99 1897:. 1893:. 1876:. 1862:. 1858:. 1841:. 1833:. 1819:. 1815:. 1798:. 1788:. 1778:. 1768:93 1766:. 1762:. 1745:. 1737:. 1723:. 1719:. 1691:. 1681:. 1671:37 1669:. 1665:. 1641:. 1629:15 1627:. 1623:. 1600:. 1588:13 1586:. 1582:. 1559:. 1549:. 1537:. 1533:. 1500:. 1482:. 1453:^ 1432:^ 1350:. 838:/ 357:bp 344:bp 256:bp 243:bp 151:; 147:: 143:; 139:: 135:; 131:: 127:; 123:: 76:, 4732:e 4725:t 4718:v 4707:. 4206:b 4201:a 4127:) 4125:b 4120:a 4118:( 4104:2 4099:1 4082:b 4077:a 3929:b 3924:a 3897:g 3892:b 3887:a 3855:b 3850:a 3808:c 3803:a 3794:) 3792:k 3787:i 3782:e 3777:d 3772:a 3770:( 3756:c 3751:b 3746:a 3573:b 3568:a 3556:b 3551:a 3479:b 3474:a 3347:k 3342:j 3337:h 3332:e 3327:d 3322:a 3285:b 3280:a 3228:f 3223:e 3218:d 3213:c 3208:b 3203:a 3191:C 3186:B 3181:A 3164:P 3159:L 3154:E 3076:f 3071:e 3066:d 3061:c 3056:b 3051:a 3009:d 3004:c 2999:b 2994:a 2937:B 2932:A 2850:B 2845:A 2818:d 2813:c 2808:b 2803:a 2781:a 2749:ε 2744:δ 2739:γ 2684:) 2666:e 2659:t 2652:v 2605:e 2598:t 2591:v 2559:. 2537:: 2516:. 2492:: 2471:. 2449:: 2428:. 2414:: 2408:5 2393:. 2371:: 2350:. 2336:: 2315:. 2301:: 2280:. 2258:: 2237:. 2223:: 2202:. 2182:: 2165:. 2145:: 2139:9 2128:. 2104:: 2096:: 2075:. 2061:: 2040:. 2018:: 1997:. 1983:: 1962:. 1948:: 1927:. 1905:: 1884:. 1870:: 1849:. 1827:: 1806:. 1782:: 1774:: 1753:. 1731:: 1699:. 1677:: 1649:. 1635:: 1608:. 1594:: 1567:. 1545:: 1539:7 1518:. 1504:. 1486:. 1331:( 1325:D 1321:C 1315:( 275:) 172:) 155::

Index


PDB
PDBe
RCSB
1OLZ
3OL2
Aliases
SEMA4D
OMIM
601866
MGI
109244
HomoloGene
21282
GeneCards
SEMA4D
OMA
SEMA4D - orthologs
Human
Chromosome 9 (human)
Chr.
Chromosome 9 (human)
Chromosome 9 (human)
Genomic location for SEMA4D
Genomic location for SEMA4D
Band
bp
bp
Mouse
Chromosome 13 (mouse)

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