242:
219:
116:
141:
493:
500:
248:
147:
1261:
1017:
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage
255:
154:
728:
709:
77:
1178:"Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation"
1330:
1306:
1113:
Kingsbury GA, Feeney LA, Nong Y, Calandra SA, Murphy CJ, Corcoran JM, Wang Y, Prabhu Das MR, Busfield SJ, Fraser CC, Villeval JL (May 2001).
1095:
1077:
1325:
936:
241:
943:
218:
1157:
1064:
1043:
1060:
140:
115:
1039:
57:
254:
153:
247:
146:
1299:
773:
65:
754:
1292:
129:
44:
894:
847:
89:
919:
898:
868:
843:
492:
1242:
1199:
1136:
37:
1276:
1232:
1224:
1189:
1126:
499:
334:
265:
209:
164:
85:
309:
1237:
1213:"Signal peptide prediction based on analysis of experimentally verified cleavage sites"
1212:
643:
638:
633:
628:
623:
618:
613:
608:
603:
598:
593:
588:
572:
567:
562:
546:
541:
1319:
1018:
commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
528:
69:
1272:
327:
106:
93:
1194:
1177:
1131:
1114:
1100:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1082:
National Center for
Biotechnology Information, U.S. National Library of Medicine
410:
1115:"Cloning, expression, and function of BLAME, a novel member of the CD2 family"
226:
123:
73:
673:
470:
348:
293:
280:
192:
179:
81:
1246:
1203:
1140:
983:
978:
624:
negative regulation of respiratory burst involved in inflammatory response
967:
818:
799:
1228:
999:
785:
740:
951:
695:
1260:
1176:
Tangye SG, Nichols KE, Hare NJ, van de Weerdt BC (September 2003).
658:
654:
1268:
1006:
508:
61:
317:
1280:
589:
leukocyte chemotaxis involved in inflammatory response
482:
912:
887:
861:
836:
1056:
1054:
1052:
1035:
1033:
1031:
264:
163:
644:negative regulation of dendritic cell chemotaxis
1061:GRCm38: Ensembl release 89: ENSMUSG00000053318
1300:
8:
599:negative regulation of macrophage chemotaxis
48:, BLAME, CD353, SBBI42, SLAM family member 8
1040:GRCh38: Ensembl release 89: ENSG00000158714
639:negative regulation of neutrophil migration
1307:
1293:
1158:"Entrez Gene: SLAMF8 SLAM family member 8"
669:
629:negative regulation of monocyte chemotaxis
524:
305:
204:
101:
1236:
1193:
1130:
1152:
1150:
1027:
604:regulation of NAD(P)H oxidase activity
18:
269:
230:
225:
168:
127:
122:
7:
1257:
1255:
619:regulation of B cell differentiation
1211:Zhang Z, Henzel WJ (October 2004).
1279:. You can help Knowledge (XXG) by
909:
884:
858:
833:
809:
790:
764:
745:
719:
700:
487:
405:
343:
322:
14:
1002:that in humans is encoded by the
1259:
498:
491:
433:lumbar subsegment of spinal cord
253:
246:
240:
217:
152:
145:
139:
114:
568:integral component of membrane
509:More reference expression data
471:More reference expression data
1:
1331:Human chromosome 1 gene stubs
614:regulation of kinase activity
609:defense response to bacterium
594:B-1 B cell lineage commitment
238:
137:
16:Protein-coding gene in humans
1326:Genes on human chromosome 1
1195:10.4049/jimmunol.171.5.2485
1132:10.4049/jimmunol.166.9.5675
542:signaling receptor activity
457:subcutaneous adipose tissue
383:superficial temporal artery
1347:
1254:
1096:"Mouse PubMed Reference:"
1078:"Human PubMed Reference:"
982:
977:
973:
966:
950:
944:Chr 1: 172.41 – 172.42 Mb
937:Chr 1: 159.83 – 159.84 Mb
931:
916:
891:
880:
865:
840:
829:
816:
812:
797:
793:
784:
771:
767:
752:
748:
739:
726:
722:
707:
703:
694:
679:
672:
668:
652:
547:identical protein binding
527:
523:
506:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
634:phagosome acidification
421:mesenteric lymph nodes
1182:Journal of Immunology
1119:Journal of Immunology
996:SLAM family member 8
232:Chromosome 1 (mouse)
130:Chromosome 1 (human)
1229:10.1110/ps.04682504
1267:This article on a
774:ENSMUSG00000053318
582:Biological process
556:Cellular component
535:Molecular function
371:lower lobe of lung
94:SLAMF8 - orthologs
1288:
1287:
993:
992:
989:
988:
962:
961:
927:
926:
906:
905:
876:
875:
855:
854:
825:
824:
806:
805:
780:
779:
761:
760:
735:
734:
716:
715:
664:
663:
519:
518:
515:
514:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
1338:
1309:
1302:
1295:
1263:
1256:
1250:
1240:
1207:
1197:
1162:
1161:
1154:
1145:
1144:
1134:
1110:
1104:
1103:
1092:
1086:
1085:
1074:
1068:
1058:
1047:
1037:
975:
974:
946:
939:
922:
910:
901:
885:
881:RefSeq (protein)
871:
859:
850:
834:
810:
791:
765:
746:
720:
701:
670:
525:
511:
502:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1346:
1345:
1341:
1340:
1339:
1337:
1336:
1335:
1316:
1315:
1314:
1313:
1253:
1223:(10): 2819–24.
1217:Protein Science
1210:
1175:
1171:
1169:Further reading
1166:
1165:
1156:
1155:
1148:
1112:
1111:
1107:
1094:
1093:
1089:
1076:
1075:
1071:
1059:
1050:
1038:
1029:
1024:
1015:
984:View/Edit Mouse
979:View/Edit Human
942:
935:
932:Location (UCSC)
918:
897:
893:
867:
846:
842:
755:ENSG00000158714
648:
577:
551:
507:
497:
496:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1344:
1342:
1334:
1333:
1328:
1318:
1317:
1312:
1311:
1304:
1297:
1289:
1286:
1285:
1264:
1252:
1251:
1208:
1188:(5): 2485–95.
1172:
1170:
1167:
1164:
1163:
1146:
1125:(9): 5675–80.
1105:
1087:
1069:
1048:
1026:
1025:
1023:
1020:
1014:
1011:
991:
990:
987:
986:
981:
971:
970:
964:
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960:
959:
957:
955:
948:
947:
940:
933:
929:
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925:
924:
914:
913:
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904:
903:
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888:
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878:
877:
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873:
863:
862:
856:
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852:
838:
837:
831:
827:
826:
823:
822:
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813:
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803:
795:
794:
788:
782:
781:
778:
777:
769:
768:
762:
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758:
750:
749:
743:
737:
736:
733:
732:
724:
723:
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681:
677:
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650:
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646:
641:
636:
631:
626:
621:
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611:
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596:
591:
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583:
579:
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575:
570:
565:
559:
557:
553:
552:
550:
549:
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538:
536:
532:
531:
521:
520:
517:
516:
513:
512:
504:
503:
485:
479:
478:
475:
474:
466:
465:
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461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
387:amniotic fluid
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
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214:
213:
201:
200:
197:
196:
188:
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175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1343:
1332:
1329:
1327:
1324:
1323:
1321:
1310:
1305:
1303:
1298:
1296:
1291:
1290:
1284:
1282:
1278:
1274:
1270:
1265:
1262:
1258:
1248:
1244:
1239:
1234:
1230:
1226:
1222:
1218:
1214:
1209:
1205:
1201:
1196:
1191:
1187:
1183:
1179:
1174:
1173:
1168:
1159:
1153:
1151:
1147:
1142:
1138:
1133:
1128:
1124:
1120:
1116:
1109:
1106:
1101:
1097:
1091:
1088:
1083:
1079:
1073:
1070:
1066:
1062:
1057:
1055:
1053:
1049:
1045:
1041:
1036:
1034:
1032:
1028:
1021:
1019:
1012:
1010:
1008:
1005:
1001:
997:
985:
980:
976:
972:
969:
965:
958:
956:
953:
949:
945:
941:
938:
934:
930:
923:
921:
915:
911:
908:
902:
900:
896:
890:
886:
883:
879:
872:
870:
864:
860:
857:
851:
849:
845:
839:
835:
832:
830:RefSeq (mRNA)
828:
821:
820:
815:
811:
808:
802:
801:
796:
792:
789:
787:
783:
776:
775:
770:
766:
763:
757:
756:
751:
747:
744:
742:
738:
731:
730:
725:
721:
718:
712:
711:
706:
702:
699:
697:
693:
690:
687:
685:
682:
678:
675:
671:
667:
660:
656:
651:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
615:
612:
610:
607:
605:
602:
600:
597:
595:
592:
590:
587:
586:
584:
581:
580:
574:
571:
569:
566:
564:
561:
560:
558:
555:
554:
548:
545:
543:
540:
539:
537:
534:
533:
530:
529:Gene ontology
526:
522:
510:
505:
501:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1281:expanding it
1273:chromosome 1
1266:
1220:
1216:
1185:
1181:
1122:
1118:
1108:
1099:
1090:
1081:
1072:
1016:
1003:
995:
994:
917:
895:NP_001317670
892:
866:
848:NM_001330741
841:
817:
798:
772:
753:
727:
708:
688:
683:
573:cell surface
445:right kidney
333:
326:
292:172,418,135
279:172,409,325
191:159,837,492
178:159,826,811
53:External IDs
441:granulocyte
391:gallbladder
271:1|1 H3
31:Identifiers
1320:Categories
1067:, May 2017
1046:, May 2017
1022:References
449:blastocyst
363:lymph node
337:(ortholog)
74:HomoloGene
1271:on human
920:NP_083360
899:NP_064510
869:NM_029084
844:NM_020125
674:Orthologs
82:GeneCards
1247:15340161
1204:12928397
1141:11313408
1063:–
1042:–
1013:Function
968:Wikidata
653:Sources:
563:membrane
367:testicle
359:appendix
1238:2286551
1065:Ensembl
1044:Ensembl
1000:protein
786:UniProt
741:Ensembl
680:Species
659:QuickGO
375:decidua
312:pattern
70:1921998
38:Aliases
1245:
1235:
1202:
1139:
1004:SLAMF8
954:search
952:PubMed
819:Q9D3G2
800:Q9P0V8
696:Entrez
483:BioGPS
453:thymus
437:morula
429:spleen
425:embryo
395:rectum
379:spleen
170:1q23.2
86:SLAMF8
62:606620
45:SLAMF8
22:SLAMF8
1275:is a
998:is a
729:74748
710:56833
689:Mouse
684:Human
655:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:10589
1277:stub
1269:gene
1243:PMID
1200:PMID
1137:PMID
1007:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1233:PMC
1225:doi
1190:doi
1186:171
1127:doi
1123:166
288:End
187:End
90:OMA
66:MGI
1322::
1241:.
1231:.
1221:13
1219:.
1215:.
1198:.
1184:.
1180:.
1149:^
1135:.
1121:.
1117:.
1098:.
1080:.
1051:^
1030:^
1009:.
657:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1308:e
1301:t
1294:v
1283:.
1249:.
1227::
1206:.
1192::
1160:.
1143:.
1129::
1102:.
1084:.
212:)
109:)
92::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
