Knowledge (XXG)

SLU7

Source 📝

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Shomron N, Alberstein M, Reznik M, Ast G (Mar 2005). "Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing".
1342:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" 1683: 1165: 1659: 1147: 1678: 243: 989: 996: 220: 1383:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
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that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the
1130: 142: 117: 1109: 1185:"Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing" 1085: 59: 256: 155: 1652: 249: 148: 802: 67: 1430:"Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus" 1299:"Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing" 783: 1567:
Chua K, Reed R (2000). "The RNA splicing factor hSlu7 is required for correct 3' splice-site choice".
1645: 1484: 1392: 131: 46: 1526:"An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing" 1069: 947: 943: 933: 929: 925: 921: 1592: 1416: 1257: 91: 1473:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 972: 968: 917: 897: 893: 872: 1584: 1555: 1512: 1459: 1408: 1371: 1328: 1249: 1214: 39: 1629: 1576: 1545: 1537: 1502: 1492: 1449: 1441: 1400: 1361: 1353: 1318: 1310: 1241: 1204: 1196: 336: 267: 211: 166: 1073: 311: 87: 1488: 1396: 1366: 1341: 1323: 1298: 1081: 1507: 1472: 1454: 1429: 1209: 1184: 672: 667: 662: 657: 652: 647: 642: 637: 632: 627: 622: 617: 601: 596: 591: 586: 581: 576: 571: 566: 561: 556: 540: 535: 530: 525: 520: 515: 1672: 1550: 1525: 502: 1541: 1261: 1084:
that is found in other splicing factors and is involved in protein-nucleic acid and
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1077: 400: 228: 125: 75: 1445: 702: 460: 350: 295: 282: 194: 181: 83: 1588: 1559: 1516: 1497: 1463: 1412: 1375: 1332: 1253: 1218: 1036: 1031: 1200: 1065: 1020: 847: 828: 1404: 1357: 1314: 1052: 814: 769: 1245: 1004: 724: 1613: 1580: 687: 683: 1621: 1279:"Entrez Gene: SLU7 SLU7 splicing factor homolog (S. cerevisiae)" 1059: 63: 1471:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
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Alberstein M, Amit M, Vaknin K, et al. (2008).
961: 916: 886: 865: 1126: 1124: 1122: 1105: 1103: 1101: 266: 165: 521:second spliceosomal transesterification activity 623:RNA splicing, via transesterification reactions 16:Protein-coding gene in the species Homo sapiens 1131:GRCm38: Ensembl release 89: ENSMUSG00000020409 673:termination of RNA polymerase II transcription 1653: 1072:steps. The protein encoded by this gene is a 8: 1110:GRCh38: Ensembl release 89: ENSG00000164609 50:, 9G8, hSlu7, SLU7 homolog, splicing factor 1660: 1646: 913: 698: 648:alternative mRNA splicing, via spliceosome 498: 307: 206: 103: 1549: 1506: 1496: 1453: 1365: 1322: 1208: 1273: 1271: 577:intracellular membrane-bounded organelle 1097: 582:small nuclear ribonucleoprotein complex 20: 271: 232: 227: 170: 129: 124: 7: 1610: 1608: 1428:Shomron N, Reznik M, Ast G (2005). 1632:. You can help Knowledge (XXG) by 1068:splicing occurs in two sequential 958: 883: 862: 838: 819: 793: 774: 748: 729: 477: 395: 345: 324: 14: 1055:that in humans is encoded by the 1612: 255: 248: 242: 219: 154: 147: 141: 116: 1542:10.1128/MCB.21.5.1509-1514.2001 643:intracellular protein transport 633:mRNA 3'-splice site recognition 516:pre-mRNA 3'-splice site binding 658:mRNA splicing, via spliceosome 461:More reference expression data 1: 1684:Human chromosome 5 gene stubs 1049:Pre-mRNA-splicing factor SLU7 443:vestibular sensory epithelium 240: 139: 1477:Proc. Natl. Acad. Sci. U.S.A 1086:protein-protein interactions 1080:and contains a zinc knuckle 567:catalytic step 2 spliceosome 1679:Genes on human chromosome 5 1183:Chua K, Reed R (May 1999). 1700: 1607: 1166:"Mouse PubMed Reference:" 1148:"Human PubMed Reference:" 1035: 1030: 1026: 1019: 1003: 984: 965: 940: 909: 890: 869: 858: 845: 841: 826: 822: 813: 800: 796: 781: 777: 768: 755: 751: 736: 732: 723: 708: 701: 697: 681: 618:cellular response to heat 501: 497: 485: 480: 471: 458: 407: 398: 357: 348: 318: 310: 306: 289: 276: 239: 218: 209: 205: 188: 175: 138: 115: 106: 102: 57: 54: 44: 37: 32: 28: 23: 997:Chr 11: 43.32 – 43.34 Mb 990:Chr 5: 160.4 – 160.42 Mb 663:mRNA export from nucleus 1524:Chua K, Reed R (2001). 1446:10.1091/mbc.E04-02-0152 653:RNA export from nucleus 1498:10.1073/pnas.242603899 668:mRNA 3'-end processing 435:deep cerebellar nuclei 373:superior frontal gyrus 234:Chromosome 11 (mouse) 1201:10.1101/gad.13.7.841 587:spliceosomal complex 536:nucleic acid binding 439:facial motor nucleus 132:Chromosome 5 (human) 1489:2002PNAS...9916899M 1405:10.1038/nature04209 1397:2005Natur.437.1173R 1070:transesterification 385:islet of Langerhans 1620:This article on a 1358:10.1101/gr.4039406 1315:10.1261/rna.492907 803:ENSMUSG00000020409 611:Biological process 550:Cellular component 509:Molecular function 1641: 1640: 1483:(26): 16899–903. 1246:10.1242/jcs.01720 1046: 1045: 1042: 1041: 1015: 1014: 980: 979: 955: 954: 905: 904: 880: 879: 854: 853: 835: 834: 809: 808: 790: 789: 764: 763: 745: 744: 693: 692: 526:metal ion binding 493: 492: 489: 488: 467: 466: 454: 453: 392: 391: 381:prefrontal cortex 302: 301: 201: 200: 1691: 1662: 1655: 1648: 1616: 1609: 1600: 1575:(6758): 207–10. 1563: 1553: 1520: 1510: 1500: 1467: 1457: 1424: 1391:(7062): 1173–8. 1379: 1369: 1336: 1326: 1283: 1282: 1275: 1266: 1265: 1240:(Pt 6): 1151–9. 1229: 1223: 1222: 1212: 1180: 1174: 1173: 1162: 1156: 1155: 1144: 1138: 1128: 1117: 1107: 1028: 1027: 999: 992: 975: 959: 950: 914: 910:RefSeq (protein) 900: 884: 875: 863: 839: 820: 794: 775: 749: 730: 699: 541:zinc ion binding 499: 478: 463: 447:ventricular zone 423:genital tubercle 403: 401:Top expressed in 396: 353: 351:Top expressed in 346: 325: 308: 298: 285: 274: 259: 252: 246: 235: 223: 207: 197: 184: 173: 158: 151: 145: 134: 120: 104: 98: 96:SLU7 - orthologs 49: 42: 21: 1699: 1698: 1694: 1693: 1692: 1690: 1689: 1688: 1669: 1668: 1667: 1666: 1605: 1603: 1566: 1530:Mol. Cell. Biol 1523: 1470: 1434:Mol. Biol. Cell 1427: 1382: 1339: 1309:(11): 1988–99. 1296: 1292: 1290:Further reading 1287: 1286: 1277: 1276: 1269: 1231: 1230: 1226: 1182: 1181: 1177: 1164: 1163: 1159: 1146: 1145: 1141: 1129: 1120: 1108: 1099: 1094: 1074:splicing factor 1037:View/Edit Mouse 1032:View/Edit Human 995: 988: 985:Location (UCSC) 971: 967: 946: 942: 936: 932: 928: 924: 920: 896: 892: 871: 784:ENSG00000164609 677: 628:mRNA processing 606: 545: 531:protein binding 459: 450: 445: 441: 437: 433: 429: 425: 421: 417: 413: 399: 388: 383: 379: 375: 371: 367: 365:Achilles tendon 363: 349: 293: 280: 273:11|11 B1.1 272: 262: 261: 260: 253: 233: 210:Gene location ( 192: 179: 171: 161: 160: 159: 152: 130: 107:Gene location ( 58: 45: 38: 17: 12: 11: 5: 1697: 1695: 1687: 1686: 1681: 1671: 1670: 1665: 1664: 1657: 1650: 1642: 1639: 1638: 1617: 1602: 1601: 1564: 1536:(5): 1509–14. 1521: 1468: 1440:(8): 3782–95. 1425: 1380: 1337: 1293: 1291: 1288: 1285: 1284: 1267: 1224: 1175: 1157: 1139: 1118: 1096: 1095: 1093: 1090: 1044: 1043: 1040: 1039: 1034: 1024: 1023: 1017: 1016: 1013: 1012: 1010: 1008: 1001: 1000: 993: 986: 982: 981: 978: 977: 963: 962: 956: 953: 952: 938: 937: 911: 907: 906: 903: 902: 888: 887: 881: 878: 877: 867: 866: 860: 856: 855: 852: 851: 843: 842: 836: 833: 832: 824: 823: 817: 811: 810: 807: 806: 798: 797: 791: 788: 787: 779: 778: 772: 766: 765: 762: 761: 753: 752: 746: 743: 742: 734: 733: 727: 721: 720: 715: 710: 706: 705: 695: 694: 691: 690: 679: 678: 676: 675: 670: 665: 660: 655: 650: 645: 640: 635: 630: 625: 620: 614: 612: 608: 607: 605: 604: 599: 594: 589: 584: 579: 574: 569: 564: 559: 553: 551: 547: 546: 544: 543: 538: 533: 528: 523: 518: 512: 510: 506: 505: 495: 494: 491: 490: 487: 486: 483: 482: 475: 469: 468: 465: 464: 456: 455: 452: 451: 449: 448: 444: 440: 436: 432: 428: 424: 420: 416: 412: 408: 405: 404: 393: 390: 389: 387: 386: 382: 378: 374: 370: 366: 362: 358: 355: 354: 342: 341: 333: 322: 316: 315: 312:RNA expression 304: 303: 300: 299: 291: 287: 286: 278: 275: 270: 264: 263: 254: 247: 241: 237: 236: 231: 225: 224: 216: 215: 203: 202: 199: 198: 190: 186: 185: 177: 174: 169: 163: 162: 153: 146: 140: 136: 135: 128: 122: 121: 113: 112: 100: 99: 56: 52: 51: 43: 35: 34: 30: 29: 26: 25: 15: 13: 10: 9: 6: 4: 3: 2: 1696: 1685: 1682: 1680: 1677: 1676: 1674: 1663: 1658: 1656: 1651: 1649: 1644: 1643: 1637: 1635: 1631: 1627: 1623: 1618: 1615: 1611: 1606: 1598: 1594: 1590: 1586: 1582: 1581:10.1038/46086 1578: 1574: 1570: 1565: 1561: 1557: 1552: 1547: 1543: 1539: 1535: 1531: 1527: 1522: 1518: 1514: 1509: 1504: 1499: 1494: 1490: 1486: 1482: 1478: 1474: 1469: 1465: 1461: 1456: 1451: 1447: 1443: 1439: 1435: 1431: 1426: 1422: 1418: 1414: 1410: 1406: 1402: 1398: 1394: 1390: 1386: 1381: 1377: 1373: 1368: 1363: 1359: 1355: 1351: 1347: 1343: 1338: 1334: 1330: 1325: 1320: 1316: 1312: 1308: 1304: 1300: 1295: 1294: 1289: 1280: 1274: 1272: 1268: 1263: 1259: 1255: 1251: 1247: 1243: 1239: 1235: 1228: 1225: 1220: 1216: 1211: 1206: 1202: 1198: 1195:(7): 841–50. 1194: 1190: 1186: 1179: 1176: 1171: 1167: 1161: 1158: 1153: 1149: 1143: 1140: 1136: 1132: 1127: 1125: 1123: 1119: 1115: 1111: 1106: 1104: 1102: 1098: 1091: 1089: 1087: 1083: 1079: 1075: 1071: 1067: 1063: 1061: 1058: 1054: 1050: 1038: 1033: 1029: 1025: 1022: 1018: 1011: 1009: 1006: 1002: 998: 994: 991: 987: 983: 976: 974: 970: 964: 960: 957: 951: 949: 945: 939: 935: 931: 927: 923: 919: 915: 912: 908: 901: 899: 895: 889: 885: 882: 876: 874: 868: 864: 861: 859:RefSeq (mRNA) 857: 850: 849: 844: 840: 837: 831: 830: 825: 821: 818: 816: 812: 805: 804: 799: 795: 792: 786: 785: 780: 776: 773: 771: 767: 760: 759: 754: 750: 747: 741: 740: 735: 731: 728: 726: 722: 719: 716: 714: 711: 707: 704: 700: 696: 689: 685: 680: 674: 671: 669: 666: 664: 661: 659: 656: 654: 651: 649: 646: 644: 641: 639: 636: 634: 631: 629: 626: 624: 621: 619: 616: 615: 613: 610: 609: 603: 600: 598: 595: 593: 590: 588: 585: 583: 580: 578: 575: 573: 570: 568: 565: 563: 562:nuclear speck 560: 558: 555: 554: 552: 549: 548: 542: 539: 537: 534: 532: 529: 527: 524: 522: 519: 517: 514: 513: 511: 508: 507: 504: 503:Gene ontology 500: 496: 484: 479: 476: 474: 470: 462: 457: 446: 442: 438: 434: 430: 426: 422: 418: 414: 410: 409: 406: 402: 397: 394: 384: 380: 376: 372: 368: 364: 360: 359: 356: 352: 347: 344: 343: 340: 338: 334: 332: 331: 327: 326: 323: 321: 317: 313: 309: 305: 297: 292: 288: 284: 279: 269: 265: 258: 251: 245: 238: 230: 226: 222: 217: 213: 208: 204: 196: 191: 187: 183: 178: 168: 164: 157: 150: 144: 137: 133: 127: 123: 119: 114: 110: 105: 101: 97: 93: 89: 85: 81: 77: 73: 69: 65: 61: 53: 48: 41: 36: 31: 27: 22: 19: 1634:expanding it 1626:chromosome 5 1619: 1604: 1572: 1568: 1533: 1529: 1480: 1476: 1437: 1433: 1388: 1384: 1352:(1): 55–65. 1349: 1345: 1306: 1302: 1237: 1233: 1227: 1192: 1188: 1178: 1169: 1160: 1151: 1142: 1064: 1056: 1048: 1047: 966: 948:NP_001351452 944:NP_001351451 941: 934:NP_001351450 930:NP_001351449 926:NP_001351447 922:NP_001351446 891: 870: 846: 827: 801: 782: 756: 737: 717: 712: 638:RNA splicing 419:otic placode 415:otic vesicle 335: 328: 193:160,421,711 180:160,401,641 55:External IDs 18: 1078:spliceosome 597:nucleoplasm 427:granulocyte 377:sural nerve 294:43,338,808 281:43,324,571 33:Identifiers 1673:Categories 1346:Genome Res 1234:J Cell Sci 1137:, May 2017 1116:, May 2017 1092:References 339:(ortholog) 76:HomoloGene 1624:on human 1189:Genes Dev 973:NP_945174 969:NP_683514 918:NP_006416 898:NM_198936 894:NM_148673 873:NM_006425 703:Orthologs 557:cytoplasm 84:GeneCards 1589:10647016 1560:11238888 1517:12477932 1464:15181151 1413:16189514 1376:16344560 1333:17804646 1262:18873022 1254:15728250 1219:10197984 1133:– 1112:– 1066:Pre-mRNA 1021:Wikidata 682:Sources: 572:membrane 361:testicle 1597:4428185 1485:Bibcode 1421:4427026 1393:Bibcode 1367:1356129 1324:2040095 1135:Ensembl 1114:Ensembl 1053:protein 815:UniProt 770:Ensembl 709:Species 688:QuickGO 602:cytosol 592:nucleus 411:saccule 314:pattern 72:2385598 40:Aliases 1595:  1587:  1569:Nature 1558:  1548:  1515:  1508:139241 1505:  1462:  1455:491837 1452:  1419:  1411:  1385:Nature 1374:  1364:  1331:  1321:  1260:  1252:  1217:  1210:316594 1207:  1007:search 1005:PubMed 848:Q8BHJ9 829:O95391 758:193116 725:Entrez 473:BioGPS 431:zygote 172:5q33.3 64:605974 1628:is a 1593:S2CID 1551:86697 1417:S2CID 1258:S2CID 1082:motif 1051:is a 739:10569 718:Mouse 713:Human 684:Amigo 369:colon 337:Mouse 330:Human 277:Start 212:Mouse 176:Start 109:Human 1630:stub 1622:gene 1585:PMID 1556:PMID 1513:PMID 1460:PMID 1409:PMID 1372:PMID 1329:PMID 1250:PMID 1215:PMID 1060:gene 1057:SLU7 320:Bgee 268:Band 229:Chr. 167:Band 126:Chr. 88:SLU7 80:4690 60:OMIM 47:SLU7 24:SLU7 1577:doi 1573:402 1546:PMC 1538:doi 1503:PMC 1493:doi 1450:PMC 1442:doi 1401:doi 1389:437 1362:PMC 1354:doi 1319:PMC 1311:doi 1303:RNA 1242:doi 1238:118 1205:PMC 1197:doi 481:n/a 290:End 189:End 92:OMA 68:MGI 1675:: 1591:. 1583:. 1571:. 1554:. 1544:. 1534:21 1532:. 1528:. 1511:. 1501:. 1491:. 1481:99 1479:. 1475:. 1458:. 1448:. 1438:15 1436:. 1432:. 1415:. 1407:. 1399:. 1387:. 1370:. 1360:. 1350:16 1348:. 1344:. 1327:. 1317:. 1307:13 1305:. 1301:. 1270:^ 1256:. 1248:. 1236:. 1213:. 1203:. 1193:13 1191:. 1187:. 1168:. 1150:. 1121:^ 1100:^ 1088:. 1062:. 686:/ 296:bp 283:bp 195:bp 182:bp 90:; 86:: 82:; 78:: 74:; 70:: 66:; 62:: 1661:e 1654:t 1647:v 1636:. 1599:. 1579:: 1562:. 1540:: 1519:. 1495:: 1487:: 1466:. 1444:: 1423:. 1403:: 1395:: 1378:. 1356:: 1335:. 1313:: 1281:. 1264:. 1244:: 1221:. 1199:: 1172:. 1154:. 214:) 111:) 94::

Index

Aliases
SLU7
OMIM
605974
MGI
2385598
HomoloGene
4690
GeneCards
SLU7
OMA
SLU7 - orthologs
Human
Chromosome 5 (human)
Chr.
Chromosome 5 (human)
Chromosome 5 (human)
Genomic location for SLU7
Genomic location for SLU7
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.
Chromosome 11 (mouse)
Genomic location for SLU7
Genomic location for SLU7
Band
bp

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