209:
234:
1798:
42:
240:
1813:
1838:
1661:
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction
1709:
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P,
1275:
Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999).
68:
1710:
Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network".
1134:
Saito H, Fujiwara T, Shin S, Okui K, Nakamura Y (Jan 1997). "Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2".
1487:"Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP"
1797:
247:
141:, 15.5K, FA-1, FA1, NHPX, OTK27, SNRNP15-5, SPAG12, SSFA1, NHP2L1, SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5), small nuclear ribonucleoprotein 13
736:
717:
170:
1571:
Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005).
1879:
1898:
1777:
1116:
1098:
1812:
1319:
Chang MS, Sasaki H, Campbell MS, Kraeft SK, Sutherland R, Yang CY, Liu Y, Auclair D, Hao L, Sonoda H, Ferland LH, Chen LB (Dec 1999).
1186:
Chang MS, Sasaki H, Campbell MS, Kraeft SK, Sutherland R, Yang CY, Liu Y, Auclair D, Hao L, Sonoda H, Ferland LH, Chen LB (Dec 1999).
944:
1444:"In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles"
1172:
1085:
233:
208:
65:
1081:
1029:
NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the
150:
1053:
246:
1872:
239:
1770:
1234:"Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA"
1025:
781:
158:
1616:
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (Jan 2005). "Nucleolar proteome dynamics".
762:
1528:
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (Nov 2002).
1903:
1865:
222:
1763:
1719:
1625:
1412:
1289:
137:
902:
851:
1743:
1697:
1649:
182:
927:
906:
876:
855:
1735:
1689:
1641:
1604:
1559:
1516:
1473:
1430:
1387:
1342:
1307:
1263:
1209:
1151:
130:
58:
1849:
1727:
1679:
1671:
1633:
1594:
1584:
1549:
1541:
1506:
1498:
1463:
1455:
1420:
1377:
1367:
1332:
1297:
1253:
1245:
1199:
1143:
326:
257:
178:
1684:
1382:
1232:
Nottrott S, Hartmuth K, Fabrizio P, Urlaub H, Vidovic I, Ficner R, Lührmann R (Nov 1999).
301:
1723:
1629:
1416:
1321:"HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation"
1293:
1188:"HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation"
41:
1468:
1443:
1399:
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (Jan 2002).
1258:
1233:
1599:
1572:
1554:
1529:
1511:
1486:
1425:
1400:
1372:
1355:
651:
646:
641:
636:
631:
626:
621:
616:
611:
606:
590:
585:
580:
575:
570:
565:
560:
555:
550:
545:
540:
535:
530:
525:
509:
504:
499:
494:
489:
484:
479:
474:
1892:
1502:
461:
1806:: CRYSTAL STRUCTURE OF THE SPLICEOSOMAL 15.5KD PROTEIN BOUND TO A U4 SNRNA FRAGMENT
1747:
1701:
1653:
1356:"Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment"
1044:. Two transcript variants encoding the same protein have been found for this gene.
319:
199:
162:
1173:"Entrez Gene: NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)"
186:
1121:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1103:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1675:
1249:
216:
166:
1589:
1337:
1320:
1204:
1187:
1545:
1037:
1030:
681:
419:
340:
285:
272:
174:
1739:
1693:
1645:
1608:
1563:
1520:
1477:
1434:
1391:
1346:
1311:
1267:
1213:
1034:
1459:
1155:
989:
984:
1041:
973:
826:
807:
1731:
1637:
1845:
1005:
793:
748:
1837:
1147:
107:
103:
99:
95:
91:
87:
957:
703:
17:
1354:
Vidovic I, Nottrott S, Hartmuth K, Lührmann R, Ficner R (Dec 2000).
1302:
1277:
1573:"A genome annotation-driven approach to cloning the human ORFeome"
1057:
666:
662:
1012:
154:
1759:
1755:
1023:
Originally named because of its sequence similarity to the
309:
1853:
431:
1401:"Directed proteomic analysis of the human nucleolus"
1821:: Structure of a human Prp31-15.5K-U4 snRNA complex
920:
895:
869:
844:
1662:network: a resource for annotating the proteome".
1530:"Functional proteomic analysis of human nucleolus"
1077:
1075:
1073:
256:
1485:Watkins NJ, Dickmanns A, Lührmann R (Dec 2002).
27:Protein-coding gene in the species Homo sapiens
1873:
1771:
8:
1082:GRCh38: Ensembl release 89: ENSG00000100138
1880:
1866:
1778:
1764:
1756:
677:
457:
297:
194:
76:
1683:
1598:
1588:
1553:
1510:
1467:
1424:
1381:
1371:
1336:
1301:
1278:"The DNA sequence of human chromosome 22"
1257:
1203:
1167:
1165:
1793:
1069:
31:
261:
220:
215:
7:
1834:
1832:
1325:The Journal of Biological Chemistry
1192:The Journal of Biological Chemistry
1852:. You can help Knowledge (XXG) by
917:
892:
866:
841:
817:
798:
772:
753:
727:
708:
436:
397:
335:
314:
25:
1008:that in humans is encoded by the
561:cytosolic large ribosomal subunit
1836:
1811:
1796:
1503:10.1128/MCB.22.23.8342-8352.2002
1442:Leung AK, Lamond AI (May 2002).
586:U2-type precatalytic spliceosome
245:
238:
232:
207:
40:
1685:11858/00-001M-0000-0010-8592-0
1491:Molecular and Cellular Biology
1383:11858/00-001M-0000-0012-F75C-F
1136:Cytogenetics and Cell Genetics
617:mRNA splicing, via spliceosome
420:More reference expression data
1:
1534:Molecular Biology of the Cell
1426:10.1016/S0960-9822(01)00650-9
1373:10.1016/S1097-2765(00)00131-3
230:
1899:Genes on human chromosome 22
546:U4/U6 x U5 tri-snRNP complex
1448:The Journal of Cell Biology
375:stromal cell of endometrium
1920:
1831:
1676:10.1016/j.cell.2005.08.029
581:protein-containing complex
1791:
1117:"Mouse PubMed Reference:"
1099:"Human PubMed Reference:"
988:
983:
979:
972:
956:
939:
924:
899:
888:
873:
848:
837:
824:
820:
805:
801:
792:
779:
775:
760:
756:
747:
734:
730:
715:
711:
702:
687:
680:
676:
660:
591:ribonucleoprotein complex
556:dense fibrillar component
460:
456:
444:
439:
430:
417:
404:
400:
347:
338:
308:
300:
296:
279:
266:
229:
206:
197:
193:
148:
145:
135:
128:
123:
84:
79:
62:
57:
52:
48:
39:
34:
1590:10.1186/gb-2004-5-10-r84
1338:10.1074/jbc.274.51.36544
1250:10.1093/emboj/18.21.6119
1205:10.1074/jbc.274.51.36544
1052:SNU13 has been shown to
1026:Saccharomyces cerevisiae
945:Chr 22: 41.67 – 41.69 Mb
566:precatalytic spliceosome
541:small-subunit processome
1546:10.1091/mbc.E02-05-0271
652:box C/D snoRNP assembly
1848:-related article is a
632:maturation of SSU-rRNA
627:maturation of LSU-rRNA
1460:10.1083/jcb.200201120
223:Chromosome 22 (human)
647:single fertilization
637:protein biosynthesis
531:spliceosomal complex
490:U4atac snRNA binding
80:List of PDB id codes
53:Available structures
1732:10.1038/nature04209
1724:2005Natur.437.1173R
1638:10.1038/nature03207
1630:2005Natur.433...77A
1417:2002CBio...12....1A
1294:1999Natur.402..489D
1002:NHP2-like protein 1
612:ribosome biogenesis
571:box C/D RNP complex
510:box C/D RNA binding
1033:. It binds to the
782:ENSMUSG00000063480
600:Biological process
519:Cellular component
468:Molecular function
363:right frontal lobe
1861:
1860:
1829:
1828:
1148:10.1159/000134186
999:
998:
995:
994:
968:
967:
935:
934:
914:
913:
884:
883:
863:
862:
833:
832:
814:
813:
788:
787:
769:
768:
743:
742:
724:
723:
672:
671:
475:U3 snoRNA binding
452:
451:
448:
447:
426:
425:
413:
412:
394:
393:
355:prefrontal cortex
292:
291:
187:SNU13 - orthologs
119:
118:
115:
114:
63:Ortholog search:
16:(Redirected from
1911:
1882:
1875:
1868:
1840:
1833:
1815:
1800:
1780:
1773:
1766:
1757:
1751:
1718:(7062): 1173–8.
1705:
1687:
1657:
1612:
1602:
1592:
1567:
1557:
1524:
1514:
1481:
1471:
1438:
1428:
1395:
1385:
1375:
1350:
1340:
1315:
1305:
1288:(6761): 489–95.
1271:
1261:
1238:The EMBO Journal
1218:
1217:
1207:
1183:
1177:
1176:
1169:
1160:
1159:
1131:
1125:
1124:
1113:
1107:
1106:
1095:
1089:
1079:
981:
980:
952:
947:
930:
918:
909:
893:
889:RefSeq (protein)
879:
867:
858:
842:
818:
799:
773:
754:
728:
709:
678:
485:U4 snRNA binding
458:
437:
422:
398:
343:
341:Top expressed in
336:
315:
298:
288:
275:
264:
249:
242:
236:
225:
211:
195:
189:
140:
133:
110:
77:
71:
50:
49:
44:
32:
21:
1919:
1918:
1914:
1913:
1912:
1910:
1909:
1908:
1889:
1888:
1887:
1886:
1830:
1825:
1822:
1816:
1807:
1801:
1787:
1784:
1754:
1708:
1660:
1624:(7021): 77–83.
1615:
1570:
1527:
1497:(23): 8342–52.
1484:
1441:
1405:Current Biology
1398:
1353:
1331:(51): 36544–9.
1318:
1274:
1244:(21): 6119–33.
1231:
1227:
1225:Further reading
1222:
1221:
1198:(51): 36544–9.
1185:
1184:
1180:
1171:
1170:
1163:
1133:
1132:
1128:
1115:
1114:
1110:
1097:
1096:
1092:
1080:
1071:
1066:
1050:
1021:
990:View/Edit Mouse
985:View/Edit Human
950:
943:
940:Location (UCSC)
926:
905:
901:
875:
854:
850:
763:ENSG00000100138
656:
642:rRNA processing
607:mRNA processing
595:
514:
495:protein binding
418:
409:
390:
387:Brodmann area 9
385:
381:
377:
373:
371:right ventricle
369:
367:muscle of thigh
365:
361:
357:
353:
339:
283:
270:
262:
252:
251:
250:
243:
221:
198:Gene location (
149:
136:
129:
86:
64:
28:
23:
22:
15:
12:
11:
5:
1917:
1915:
1907:
1906:
1901:
1891:
1890:
1885:
1884:
1877:
1870:
1862:
1859:
1858:
1841:
1827:
1826:
1824:
1823:
1817:
1810:
1808:
1802:
1795:
1792:
1789:
1788:
1785:
1783:
1782:
1775:
1768:
1760:
1753:
1752:
1706:
1658:
1613:
1577:Genome Biology
1568:
1540:(11): 4100–9.
1525:
1482:
1439:
1396:
1366:(6): 1331–42.
1360:Molecular Cell
1351:
1316:
1303:10.1038/990031
1272:
1228:
1226:
1223:
1220:
1219:
1178:
1161:
1142:(2–3): 191–3.
1126:
1108:
1090:
1068:
1067:
1065:
1062:
1049:
1046:
1020:
1017:
997:
996:
993:
992:
987:
977:
976:
970:
969:
966:
965:
963:
961:
954:
953:
948:
941:
937:
936:
933:
932:
922:
921:
915:
912:
911:
897:
896:
890:
886:
885:
882:
881:
871:
870:
864:
861:
860:
846:
845:
839:
835:
834:
831:
830:
822:
821:
815:
812:
811:
803:
802:
796:
790:
789:
786:
785:
777:
776:
770:
767:
766:
758:
757:
751:
745:
744:
741:
740:
732:
731:
725:
722:
721:
713:
712:
706:
700:
699:
694:
689:
685:
684:
674:
673:
670:
669:
658:
657:
655:
654:
649:
644:
639:
634:
629:
624:
619:
614:
609:
603:
601:
597:
596:
594:
593:
588:
583:
578:
573:
568:
563:
558:
553:
548:
543:
538:
533:
528:
522:
520:
516:
515:
513:
512:
507:
502:
500:snoRNA binding
497:
492:
487:
482:
480:ATPase binding
477:
471:
469:
465:
464:
454:
453:
450:
449:
446:
445:
442:
441:
434:
428:
427:
424:
423:
415:
414:
411:
410:
408:
405:
402:
401:
395:
392:
391:
389:
388:
384:
380:
376:
372:
368:
364:
360:
356:
352:
348:
345:
344:
332:
331:
323:
312:
306:
305:
302:RNA expression
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
219:
213:
212:
204:
203:
191:
190:
147:
143:
142:
134:
126:
125:
121:
120:
117:
116:
113:
112:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1916:
1905:
1904:Protein stubs
1902:
1900:
1897:
1896:
1894:
1883:
1878:
1876:
1871:
1869:
1864:
1863:
1857:
1855:
1851:
1847:
1842:
1839:
1835:
1820:
1814:
1809:
1805:
1799:
1794:
1790:
1781:
1776:
1774:
1769:
1767:
1762:
1761:
1758:
1749:
1745:
1741:
1737:
1733:
1729:
1725:
1721:
1717:
1713:
1707:
1703:
1699:
1695:
1691:
1686:
1681:
1677:
1673:
1670:(6): 957–68.
1669:
1665:
1659:
1655:
1651:
1647:
1643:
1639:
1635:
1631:
1627:
1623:
1619:
1614:
1610:
1606:
1601:
1596:
1591:
1586:
1582:
1578:
1574:
1569:
1565:
1561:
1556:
1551:
1547:
1543:
1539:
1535:
1531:
1526:
1522:
1518:
1513:
1508:
1504:
1500:
1496:
1492:
1488:
1483:
1479:
1475:
1470:
1465:
1461:
1457:
1454:(4): 615–29.
1453:
1449:
1445:
1440:
1436:
1432:
1427:
1422:
1418:
1414:
1410:
1406:
1402:
1397:
1393:
1389:
1384:
1379:
1374:
1369:
1365:
1361:
1357:
1352:
1348:
1344:
1339:
1334:
1330:
1326:
1322:
1317:
1313:
1309:
1304:
1299:
1295:
1291:
1287:
1283:
1279:
1273:
1269:
1265:
1260:
1255:
1251:
1247:
1243:
1239:
1235:
1230:
1229:
1224:
1215:
1211:
1206:
1201:
1197:
1193:
1189:
1182:
1179:
1174:
1168:
1166:
1162:
1157:
1153:
1149:
1145:
1141:
1137:
1130:
1127:
1122:
1118:
1112:
1109:
1104:
1100:
1094:
1091:
1087:
1083:
1078:
1076:
1074:
1070:
1063:
1061:
1059:
1055:
1047:
1045:
1043:
1039:
1036:
1032:
1028:
1027:
1018:
1016:
1014:
1011:
1007:
1003:
991:
986:
982:
978:
975:
971:
964:
962:
959:
955:
949:
946:
942:
938:
931:
929:
923:
919:
916:
910:
908:
904:
898:
894:
891:
887:
880:
878:
872:
868:
865:
859:
857:
853:
847:
843:
840:
838:RefSeq (mRNA)
836:
829:
828:
823:
819:
816:
810:
809:
804:
800:
797:
795:
791:
784:
783:
778:
774:
771:
765:
764:
759:
755:
752:
750:
746:
739:
738:
733:
729:
726:
720:
719:
714:
710:
707:
705:
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1048:Interactions
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903:NP_001003796
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852:NM_001003796
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735:
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691:
622:RNA splicing
576:U4atac snRNP
359:hypothalamus
325:
318:
146:External IDs
85:
29:
1786:PDB gallery
1583:(10): R84.
1411:(1): 1–11.
526:nucleoplasm
505:RNA binding
379:left testis
284:41,690,504
271:41,673,933
124:Identifiers
1893:Categories
1088:, May 2017
1064:References
329:(ortholog)
167:HomoloGene
1038:stem-loop
1031:tri-snRNP
928:NP_035612
907:NP_004999
877:NM_011482
856:NM_005008
682:Orthologs
551:nucleolus
351:beta cell
175:GeneCards
1740:16189514
1694:16169070
1646:15635413
1609:15461802
1564:12429849
1521:12417735
1478:12011111
1435:11790298
1392:11163207
1347:10593953
1312:10591208
1268:10545122
1214:10593953
1084:–
1054:interact
1042:U4 snRNA
1019:Function
974:Wikidata
661:Sources:
1846:protein
1748:4427026
1720:Bibcode
1702:8235923
1654:4344740
1626:Bibcode
1469:2173864
1413:Bibcode
1290:Bibcode
1259:1171676
1156:8978773
1086:Ensembl
1006:protein
794:UniProt
749:Ensembl
688:Species
667:QuickGO
536:nucleus
304:pattern
263:22q13.2
131:Aliases
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1712:Nature
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960:search
958:PubMed
827:Q9D0T1
808:P55769
704:Entrez
432:BioGPS
163:893586
155:601304
1844:This
1744:S2CID
1698:S2CID
1650:S2CID
1058:RAD17
1056:with
1010:SNU13
1004:is a
737:20826
697:Mouse
692:Human
663:Amigo
327:Mouse
320:Human
267:Start
200:Human
179:SNU13
138:SNU13
35:SNU13
18:SNU13
1850:stub
1819:2ozb
1804:1e7k
1736:PMID
1690:PMID
1664:Cell
1642:PMID
1605:PMID
1560:PMID
1517:PMID
1474:PMID
1431:PMID
1388:PMID
1343:PMID
1308:PMID
1264:PMID
1210:PMID
1152:PMID
1013:gene
718:4809
310:Bgee
258:Band
217:Chr.
171:3672
151:OMIM
108:3JCR
104:3SIV
100:3SIU
96:2OZB
92:2JNB
88:1E7K
69:RCSB
66:PDBe
1728:doi
1716:437
1680:hdl
1672:doi
1668:122
1634:doi
1622:433
1595:PMC
1585:doi
1550:PMC
1542:doi
1507:PMC
1499:doi
1464:PMC
1456:doi
1452:157
1421:doi
1378:hdl
1368:doi
1333:doi
1329:274
1298:doi
1286:402
1254:PMC
1246:doi
1200:doi
1196:274
1144:doi
1040:of
951:n/a
440:n/a
407:n/a
280:End
183:OMA
159:MGI
59:PDB
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1164:^
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1072:^
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273:bp
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