Knowledge (XXG)

Spondin 2

Source 📝

308: 285: 182: 207: 314: 213: 1568: 1512:
Kong A, Thorleifsson G, Stefansson H, Masson G, Helgason A, Gudbjartsson DF, Jonsdottir GM, Gudjonsson SA, Sverrisson S, Thorlacius T, Jonasdottir A, Hardarson GA, Palsson ST, Frigge ML, Gulcher JR, Thorsteinsdottir U, Stefansson K (March 2008). "Sequence variants in the RNF212 gene associate with
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Manda R, Kohno T, Matsuno Y, Takenoshita S, Kuwano H, Yokota J (October 1999). "Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display".
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Choy KW, Wang CC, Ogura A, Lau TK, Rogers MS, Ikeo K, Gojobori T, Lam DS, Pang CP (March 2006). "Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes".
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Yan L, Wei X, Tang QZ, Feng J, Zhang Y, Liu C, Bian ZY, Zhang LF, Chen M, Bai X, Wang AB, Fassett J, Chen Y, He YW, Yang Q, Liu PP, Li H (October 2011).
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Li Y, Cao C, Jia W, Yu L, Mo M, Wang Q, Huang Y, Lim JM, Ishihara M, Wells L, Azadi P, Robinson H, He YW, Zhang L, Mariuzza RA (February 2009).
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Feinstein Y, Klar A (June 2004). "The neuronal class 2 TSR proteins F-spondin and Mindin: a small family with divergent biological activities".
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Liao CH, Yeh SC, Huang YH, Chen RN, Tsai MM, Chen WJ, Chi HC, Tai PJ, Liao CJ, Wu SM, Cheng WL, Pai LM, Lin KH (March 2010).
1143: 206: 181: 1217:"Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling" 1122: 123: 320: 219: 313: 212: 1606: 853: 131: 834: 1599: 1522: 1271: 195: 110: 1385:"Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion" 982: 978: 931: 927: 1342:"Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule" 1546: 155: 1007: 986: 952: 923: 1538: 1500: 1471: 1441: 1406: 1371: 1328: 1299: 1246: 103: 51: 1583: 1530: 1492: 1463: 1431: 1396: 1361: 1353: 1320: 1289: 1279: 1236: 1228: 400: 331: 275: 230: 1418:
Murakoshi M, Tanimoto M, Gohda T, Hagiwara S, Takagi M, Horikoshi S, Tomino Y (July 2011).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
476: 292: 189: 139: 1534: 753: 536: 414: 359: 346: 258: 245: 147: 1542: 1504: 1475: 1467: 1445: 1410: 1375: 1357: 1332: 1303: 1250: 1196: 1071: 1066: 1436: 1419: 1260:"Spondin-2 (SPON2), a more prostate-cancer-specific diagnostic biomarker" 1232: 1055: 898: 879: 1401: 1384: 1091: 865: 820: 80: 1039: 775: 17: 1567: 1420:"Mindin: a novel marker for podocyte injury in diabetic nephropathy" 738: 734: 1575: 1098: 127: 1313:
The International Journal of Biochemistry & Cell Biology
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positive regulation of tumor necrosis factor production
1197:"Entrez Gene: Spondin 2, extracellular matrix protein" 659:
positive regulation of macrophage cytokine production
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Qian X, Li C, Pang B, Xue M, Wang J, Zhou J (2012).
1000: 971: 945: 916: 1139: 1137: 1135: 1118: 1116: 1114: 330: 229: 699:positive regulation of interleukin-6 production 27:Protein-coding gene in the species Homo sapiens 1144:GRCm38: Ensembl release 89: ENSMUSG00000037379 1607: 8: 1123:GRCh38: Ensembl release 89: ENSG00000159674 114:, DIL-1, DIL1, M-SPONDIN, MINDIN, spondin 2 1614: 1600: 749: 574: 371: 270: 167: 69: 1435: 1400: 1365: 1293: 1283: 1240: 1110: 714:cellular response to lipopolysaccharide 29: 1424:Nephrology, Dialysis, Transplantation 335: 296: 291: 234: 193: 188: 7: 1564: 1562: 724:induction of bacterial agglutination 1586:. You can help Knowledge (XXG) by 1497:10.1152/physiolgenomics.00121.2005 997: 968: 942: 913: 889: 870: 844: 825: 799: 780: 553: 471: 409: 388: 25: 1513:genome-wide recombination rate". 1094:that in humans is encoded by the 1566: 519:lumbar subsegment of spinal cord 319: 312: 306: 283: 218: 211: 205: 180: 679:response to lipopolysaccharide 537:More reference expression data 1: 1643:Human chromosome 4 gene stubs 1638:Extracellular matrix proteins 694:defense response to bacterium 304: 203: 1325:10.1016/j.biocel.2004.01.002 1285:10.1371/journal.pone.0037225 1633:Genes on human chromosome 4 654:mast cell mediated immunity 1659: 1561: 669:defense response to fungus 597:lipopolysaccharide binding 1179:"Mouse PubMed Reference:" 1161:"Human PubMed Reference:" 1070: 1065: 1061: 1054: 1038: 1019: 1004: 975: 964: 949: 920: 909: 896: 892: 877: 873: 864: 851: 847: 832: 828: 819: 806: 802: 787: 783: 774: 759: 752: 748: 732: 689:defense response to virus 577: 573: 561: 556: 547: 534: 483: 474: 421: 412: 382: 374: 370: 353: 340: 303: 282: 273: 269: 252: 239: 202: 179: 170: 166: 121: 118: 108: 101: 96: 77: 72: 55: 50: 45: 41: 37: 32: 1389:Endocrine-Related Cancer 1535:10.1126/science.1152422 1221:Cardiovascular Research 1032:Chr 5: 33.36 – 33.38 Mb 1485:Physiological Genomics 1468:10.1006/geno.1999.5939 1358:10.1038/emboj.2008.288 709:innate immune response 1025:Chr 4: 1.17 – 1.21 Mb 664:immune system process 628:extracellular exosome 638:extracellular matrix 623:extracellular region 298:Chromosome 5 (mouse) 196:Chromosome 4 (human) 73:List of PDB id codes 46:Available structures 1527:2008Sci...319.1398K 1402:10.1677/ERC-09-0050 1276:2012PLoSO...737225Q 633:extracellular space 457:right lobe of liver 433:canal of the cervix 1574:This article on a 1521:(5868): 1398–401. 1437:10.1093/ndt/gfq708 1233:10.1093/cvr/cvr159 854:ENSMUSG00000037379 647:Biological process 616:Cellular component 585:Molecular function 487:epithelium of lens 461:right uterine tube 1595: 1594: 1081: 1080: 1077: 1076: 1050: 1049: 1015: 1014: 994: 993: 960: 959: 939: 938: 905: 904: 886: 885: 860: 859: 841: 840: 815: 814: 796: 795: 744: 743: 602:metal ion binding 569: 568: 565: 564: 543: 542: 530: 529: 468: 467: 449:left uterine tube 366: 365: 265: 264: 160:SPON2 - orthologs 92: 91: 88: 87: 56:Ortholog search: 16:(Redirected from 1650: 1616: 1609: 1602: 1570: 1563: 1554: 1508: 1479: 1449: 1439: 1414: 1404: 1379: 1369: 1346:The EMBO Journal 1336: 1307: 1297: 1287: 1254: 1244: 1201: 1200: 1193: 1187: 1186: 1175: 1169: 1168: 1157: 1151: 1141: 1130: 1120: 1086:, also known as 1063: 1062: 1034: 1027: 1010: 998: 989: 969: 965:RefSeq (protein) 955: 943: 934: 914: 890: 871: 845: 826: 800: 781: 750: 575: 554: 539: 507:efferent ductule 479: 477:Top expressed in 472: 417: 415:Top expressed in 410: 389: 372: 362: 349: 338: 323: 316: 310: 299: 287: 271: 261: 248: 237: 222: 215: 209: 198: 184: 168: 162: 113: 106: 83: 70: 64: 43: 42: 30: 21: 1658: 1657: 1653: 1652: 1651: 1649: 1648: 1647: 1623: 1622: 1621: 1620: 1559: 1557: 1511: 1482: 1452: 1417: 1382: 1339: 1310: 1257: 1214: 1210: 1208:Further reading 1205: 1204: 1195: 1194: 1190: 1177: 1176: 1172: 1159: 1158: 1154: 1142: 1133: 1121: 1112: 1107: 1072:View/Edit Mouse 1067:View/Edit Human 1030: 1023: 1020:Location (UCSC) 1006: 985: 981: 977: 951: 930: 926: 922: 835:ENSG00000159674 728: 642: 611: 607:protein binding 592:antigen binding 535: 526: 523:urinary bladder 521: 517: 513: 509: 505: 501: 497: 493: 489: 475: 464: 459: 455: 451: 447: 443: 439: 435: 431: 427: 413: 357: 344: 336: 326: 325: 324: 317: 297: 274:Gene location ( 256: 243: 235: 225: 224: 223: 216: 194: 171:Gene location ( 122: 109: 102: 79: 57: 28: 23: 22: 15: 12: 11: 5: 1656: 1654: 1646: 1645: 1640: 1635: 1625: 1624: 1619: 1618: 1611: 1604: 1596: 1593: 1592: 1571: 1556: 1555: 1509: 1480: 1450: 1430:(7): 2153–60. 1415: 1380: 1337: 1308: 1255: 1211: 1209: 1206: 1203: 1202: 1188: 1170: 1152: 1131: 1109: 1108: 1106: 1103: 1079: 1078: 1075: 1074: 1069: 1059: 1058: 1052: 1051: 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1207: 1198: 1192: 1189: 1184: 1180: 1174: 1171: 1166: 1162: 1156: 1153: 1149: 1145: 1140: 1138: 1136: 1132: 1128: 1124: 1119: 1117: 1115: 1111: 1104: 1102: 1100: 1097: 1093: 1089: 1085: 1073: 1068: 1064: 1060: 1057: 1053: 1046: 1044: 1041: 1037: 1033: 1029: 1026: 1022: 1018: 1011: 1009: 1003: 999: 996: 990: 988: 984: 980: 974: 970: 967: 963: 956: 954: 948: 944: 941: 935: 933: 929: 925: 919: 915: 912: 910:RefSeq (mRNA) 908: 901: 900: 895: 891: 888: 882: 881: 876: 872: 869: 867: 863: 856: 855: 850: 846: 843: 837: 836: 831: 827: 824: 822: 818: 811: 810: 805: 801: 798: 792: 791: 786: 782: 779: 777: 773: 770: 767: 765: 762: 758: 755: 751: 747: 740: 736: 731: 725: 722: 720: 717: 715: 712: 710: 707: 705: 702: 700: 697: 695: 692: 690: 687: 685: 684:cell adhesion 682: 680: 677: 675: 674:axon guidance 672: 670: 667: 665: 662: 660: 657: 655: 652: 651: 649: 646: 645: 639: 636: 634: 631: 629: 626: 624: 621: 620: 618: 615: 614: 608: 605: 603: 600: 598: 595: 593: 590: 589: 587: 584: 583: 580: 579:Gene ontology 576: 572: 560: 555: 552: 550: 546: 538: 533: 522: 518: 515:sciatic nerve 514: 510: 506: 502: 498: 494: 490: 486: 485: 482: 478: 473: 470: 460: 456: 452: 448: 444: 440: 436: 432: 428: 424: 423: 420: 416: 411: 408: 407: 404: 402: 398: 396: 395: 391: 390: 387: 385: 381: 377: 373: 369: 361: 356: 352: 348: 343: 333: 329: 322: 315: 309: 302: 294: 290: 286: 281: 277: 272: 268: 260: 255: 251: 247: 242: 232: 228: 221: 214: 208: 201: 197: 191: 187: 183: 178: 174: 169: 165: 161: 157: 153: 149: 145: 141: 137: 133: 129: 125: 117: 112: 105: 100: 95: 84: 82: 76: 71: 68: 67: 63: 60: 53: 49: 44: 40: 36: 31: 19: 1588:expanding it 1580:chromosome 4 1573: 1558: 1518: 1514: 1488: 1484: 1459: 1455: 1427: 1423: 1392: 1388: 1349: 1345: 1316: 1312: 1267: 1263: 1227:(1): 85–94. 1224: 1220: 1191: 1182: 1173: 1164: 1155: 1095: 1087: 1083: 1082: 1005: 983:NP_001185950 979:NP_001121797 976: 950: 932:NM_001199021 928:NM_001128325 921: 897: 878: 852: 833: 807: 788: 768: 763: 719:opsonization 399: 392: 119:External IDs 78: 1491:(1): 9–15. 1462:(1): 5–14. 425:granulocyte 358:33,375,799 345:33,355,528 337:5|5 B1 97:Identifiers 1627:Categories 1150:, May 2017 1129:, May 2017 1105:References 441:myometrium 403:(ortholog) 257:1,208,962 244:1,166,932 140:HomoloGene 1578:on human 1084:Spondin 2 1008:NP_598664 987:NP_036577 953:NM_133903 924:NM_012445 754:Orthologs 499:esophagus 453:beta cell 148:GeneCards 1543:18239089 1505:16368877 1476:10512675 1456:Genomics 1446:21098016 1411:19903741 1376:19153605 1333:15094111 1304:22615945 1264:PLOS ONE 1251:21632881 1146:– 1125:– 1056:Wikidata 733:Sources: 511:duodenum 1551:5975476 1523:Bibcode 1515:Science 1367:2637340 1295:3352876 1272:Bibcode 1242:3657538 1148:Ensembl 1127:Ensembl 1092:protein 1090:, is a 866:UniProt 821:Ensembl 760:Species 739:QuickGO 429:decidua 378:pattern 136:1923724 104:Aliases 1549:  1541:  1503:  1474:  1444:  1409:  1374:  1364:  1331:  1302:  1292:  1249:  1239:  1088:mindin 1042:search 1040:PubMed 899:Q8BMS2 880:Q9BUD6 809:100689 776:Entrez 549:BioGPS 495:cornea 491:cervix 236:4p16.3 128:605918 1582:is a 1547:S2CID 1096:SPON2 790:10417 769:Mouse 764:Human 735:Amigo 401:Mouse 394:Human 341:Start 276:Mouse 240:Start 173:Human 152:SPON2 144:40843 111:SPON2 33:SPON2 18:SPON2 1584:stub 1576:gene 1539:PMID 1501:PMID 1472:PMID 1442:PMID 1407:PMID 1372:PMID 1329:PMID 1300:PMID 1247:PMID 1099:gene 384:Bgee 332:Band 293:Chr. 231:Band 190:Chr. 124:OMIM 81:3D34 62:RCSB 59:PDBe 1531:doi 1519:319 1493:doi 1464:doi 1432:doi 1397:doi 1362:PMC 1354:doi 1321:doi 1290:PMC 1280:doi 1237:PMC 1229:doi 557:n/a 503:lip 354:End 253:End 156:OMA 132:MGI 52:PDB 1629:: 1545:. 1537:. 1529:. 1517:. 1499:. 1489:25 1487:. 1470:. 1460:61 1458:. 1440:. 1428:26 1426:. 1422:. 1405:. 1393:17 1391:. 1387:. 1370:. 1360:. 1350:28 1348:. 1344:. 1327:. 1317:36 1315:. 1298:. 1288:. 1278:. 1266:. 1262:. 1245:. 1235:. 1225:92 1223:. 1219:. 1181:. 1163:. 1134:^ 1113:^ 1101:. 737:/ 360:bp 347:bp 259:bp 246:bp 154:; 150:: 146:; 142:: 138:; 134:: 130:; 126:: 1615:e 1608:t 1601:v 1590:. 1553:. 1533:: 1525:: 1507:. 1495:: 1478:. 1466:: 1448:. 1434:: 1413:. 1399:: 1378:. 1356:: 1335:. 1323:: 1306:. 1282:: 1274:: 1268:7 1253:. 1231:: 1199:. 1185:. 1167:. 278:) 175:) 158:: 20:)

Index

SPON2
PDB
PDBe
RCSB
3D34
Aliases
SPON2
OMIM
605918
MGI
1923724
HomoloGene
40843
GeneCards
SPON2
OMA
SPON2 - orthologs
Human
Chromosome 4 (human)
Chr.
Chromosome 4 (human)
Chromosome 4 (human)
Genomic location for SPON2
Genomic location for SPON2
Band
bp
bp
Mouse
Chromosome 5 (mouse)
Chr.

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