244:
221:
118:
143:
495:
250:
149:
1600:
1056:
Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (Aug 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins".
257:
156:
1549:"Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes"
79:
688:
669:
1669:
1645:
1038:
1020:
1664:
1506:"Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation"
888:
243:
895:
220:
1428:"Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker"
1092:
1471:"Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope"
1007:
986:
1003:
142:
117:
982:
59:
256:
155:
249:
148:
1277:"Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation"
1638:
733:
67:
1199:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"
714:
1631:
1386:
1333:
1124:
131:
46:
91:
1322:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
871:
850:
824:
803:
1242:"Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus"
494:
1578:
1535:
1492:
1457:
1414:
1361:
1308:
1263:
1228:
1185:
1142:
1074:
39:
1615:
1568:
1560:
1525:
1517:
1482:
1447:
1439:
1404:
1394:
1351:
1341:
1298:
1288:
1253:
1218:
1210:
1175:
1167:
1132:
1066:
336:
267:
211:
166:
87:
311:
1390:
1337:
1128:
1180:
1155:
1573:
1548:
1530:
1505:
1452:
1427:
1356:
1321:
1258:
1241:
1223:
1198:
1156:"Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium"
603:
598:
593:
588:
583:
567:
562:
557:
541:
536:
1658:
1409:
1374:
523:
71:
1611:
329:
108:
95:
1375:"Shotgun sequencing of the human transcriptome with ORF expressed sequence tags"
1043:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1025:
National Center for
Biotechnology Information, U.S. National Library of Medicine
412:
228:
125:
75:
1564:
1443:
633:
472:
350:
295:
282:
194:
181:
83:
1521:
1487:
1470:
1418:
1399:
1365:
1346:
1312:
1293:
1276:
1267:
1232:
1189:
1146:
1070:
1582:
1539:
1496:
1461:
1078:
935:
930:
1171:
919:
778:
759:
1137:
1112:
1214:
951:
745:
700:
1303:
903:
655:
1599:
1113:"The DNA sequence and biological annotation of human chromosome 1"
1373:
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000).
618:
614:
1607:
958:
63:
503:
1426:
Fischer DF, van Drunen CM, Winkler GS, et al. (1999).
1320:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1504:
Fischer DF, Gibbs S, van De Putte P, Backendorf C (1996).
319:
1619:
1275:
Cabral A, Fischer DF, Vermeij WP, Backendorf C (2003).
1197:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1111:
Gregory SG, Barlow KF, McLay KE, et al. (2006).
484:
1093:"Entrez Gene: SPRR2A small proline-rich protein 2A"
864:
843:
817:
796:
999:
997:
995:
978:
976:
974:
1547:Gibbs S, Lohman F, Teubel W, et al. (1990).
1154:Tong L, Corrales RM, Chen Z, et al. (2006).
266:
165:
16:Protein-coding gene in the species Homo sapiens
1004:GRCm38: Ensembl release 89: ENSMUSG00000046259
1639:
1240:Hong SH, Nah HY, Lee JY, et al. (2004).
8:
983:GRCh38: Ensembl release 89: ENSG00000241794
1646:
1632:
629:
519:
307:
206:
103:
1572:
1529:
1486:
1451:
1408:
1398:
1355:
1345:
1302:
1292:
1257:
1222:
1179:
1136:
970:
20:
271:
232:
227:
170:
129:
124:
7:
1596:
1594:
1618:. You can help Knowledge (XXG) by
861:
840:
814:
793:
769:
750:
724:
705:
679:
660:
489:
407:
345:
324:
14:
954:that in humans is encoded by the
1598:
1469:Steinert PM, Marekov LN (1997).
493:
255:
248:
242:
219:
154:
147:
141:
116:
50:, small proline rich protein 2A
504:More reference expression data
473:More reference expression data
1:
1670:Human chromosome 1 gene stubs
1259:10.1016/S1016-8478(23)13069-X
948:Small proline-rich protein 2A
240:
139:
1379:Proc. Natl. Acad. Sci. U.S.A
1326:Proc. Natl. Acad. Sci. U.S.A
1160:Invest. Ophthalmol. Vis. Sci
594:keratinocyte differentiation
542:structural molecule activity
1665:Genes on human chromosome 1
1686:
1593:
455:sexually immature organism
1039:"Mouse PubMed Reference:"
1021:"Human PubMed Reference:"
934:
929:
925:
918:
902:
889:Chr 1: 153.06 – 153.06 Mb
883:
868:
847:
836:
821:
800:
789:
776:
772:
757:
753:
744:
731:
727:
712:
708:
699:
686:
682:
667:
663:
654:
639:
632:
628:
612:
522:
518:
501:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
896:Chr 3: 92.29 – 92.29 Mb
1565:10.1093/nar/18.15.4401
1522:10.1128/MCB.16.10.5365
1488:10.1074/jbc.272.3.2021
1444:10.1093/nar/26.23.5288
1400:10.1073/pnas.97.7.3491
1347:10.1073/pnas.242603899
1294:10.1074/jbc.M300508200
1071:10.1006/geno.1993.1240
599:epidermis development
584:peptide cross-linking
1172:10.1167/iovs.05-1129
447:skin of external ear
273:3 F1|3 40.14 cM
234:Chromosome 3 (mouse)
132:Chromosome 1 (human)
1391:2000PNAS...97.3491D
1338:2002PNAS...9916899M
1138:10.1038/nature04727
1129:2006Natur.441..315G
369:gingival epithelium
1606:This article on a
1215:10.1101/gr.2596504
734:ENSMUSG00000046259
577:Biological process
563:cornified envelope
551:Cellular component
530:Molecular function
361:buccal mucosa cell
96:SPRR2A - orthologs
1627:
1626:
1553:Nucleic Acids Res
1432:Nucleic Acids Res
1332:(26): 16899–903.
945:
944:
941:
940:
914:
913:
879:
878:
858:
857:
832:
831:
811:
810:
785:
784:
766:
765:
740:
739:
721:
720:
695:
694:
676:
675:
624:
623:
514:
513:
510:
509:
479:
478:
466:
465:
404:
403:
381:mucosa of pharynx
302:
301:
201:
200:
1677:
1648:
1641:
1634:
1602:
1595:
1586:
1576:
1543:
1533:
1500:
1490:
1465:
1455:
1422:
1412:
1402:
1369:
1359:
1349:
1316:
1306:
1296:
1271:
1261:
1236:
1226:
1193:
1183:
1150:
1140:
1123:(7091): 315–21.
1097:
1096:
1089:
1083:
1082:
1053:
1047:
1046:
1035:
1029:
1028:
1017:
1011:
1001:
990:
980:
927:
926:
898:
891:
874:
862:
853:
841:
837:RefSeq (protein)
827:
815:
806:
794:
770:
751:
725:
706:
680:
661:
630:
520:
506:
497:
490:
475:
415:
413:Top expressed in
408:
393:nasal epithelium
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
1685:
1684:
1680:
1679:
1678:
1676:
1675:
1674:
1655:
1654:
1653:
1652:
1591:
1589:
1546:
1516:(10): 5365–74.
1510:Mol. Cell. Biol
1503:
1468:
1438:(23): 5288–94.
1425:
1372:
1319:
1287:(20): 17792–9.
1274:
1239:
1209:(10B): 2121–7.
1196:
1153:
1110:
1106:
1104:Further reading
1101:
1100:
1091:
1090:
1086:
1055:
1054:
1050:
1037:
1036:
1032:
1019:
1018:
1014:
1002:
993:
981:
972:
967:
936:View/Edit Mouse
931:View/Edit Human
894:
887:
884:Location (UCSC)
870:
849:
823:
802:
715:ENSG00000241794
608:
572:
546:
537:protein binding
502:
471:
462:
457:
453:
449:
445:
443:skin of abdomen
441:
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
1683:
1681:
1673:
1672:
1667:
1657:
1656:
1651:
1650:
1643:
1636:
1628:
1625:
1624:
1603:
1588:
1587:
1559:(15): 4401–7.
1544:
1501:
1481:(3): 2021–30.
1466:
1423:
1370:
1317:
1272:
1237:
1194:
1166:(5): 1938–46.
1151:
1107:
1105:
1102:
1099:
1098:
1084:
1048:
1030:
1012:
991:
969:
968:
966:
963:
943:
942:
939:
938:
933:
923:
922:
916:
915:
912:
911:
909:
907:
900:
899:
892:
885:
881:
880:
877:
876:
866:
865:
859:
856:
855:
845:
844:
838:
834:
833:
830:
829:
819:
818:
812:
809:
808:
798:
797:
791:
787:
786:
783:
782:
774:
773:
767:
764:
763:
755:
754:
748:
742:
741:
738:
737:
729:
728:
722:
719:
718:
710:
709:
703:
697:
696:
693:
692:
684:
683:
677:
674:
673:
665:
664:
658:
652:
651:
646:
641:
637:
636:
626:
625:
622:
621:
610:
609:
607:
606:
601:
596:
591:
589:keratinization
586:
580:
578:
574:
573:
571:
570:
565:
560:
554:
552:
548:
547:
545:
544:
539:
533:
531:
527:
526:
516:
515:
512:
511:
508:
507:
499:
498:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
378:
377:amniotic fluid
374:
373:body of tongue
370:
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
1682:
1671:
1668:
1666:
1663:
1662:
1660:
1649:
1644:
1642:
1637:
1635:
1630:
1629:
1623:
1621:
1617:
1613:
1609:
1604:
1601:
1597:
1592:
1584:
1580:
1575:
1570:
1566:
1562:
1558:
1554:
1550:
1545:
1541:
1537:
1532:
1527:
1523:
1519:
1515:
1511:
1507:
1502:
1498:
1494:
1489:
1484:
1480:
1476:
1475:J. Biol. Chem
1472:
1467:
1463:
1459:
1454:
1449:
1445:
1441:
1437:
1433:
1429:
1424:
1420:
1416:
1411:
1406:
1401:
1396:
1392:
1388:
1385:(7): 3491–6.
1384:
1380:
1376:
1371:
1367:
1363:
1358:
1353:
1348:
1343:
1339:
1335:
1331:
1327:
1323:
1318:
1314:
1310:
1305:
1300:
1295:
1290:
1286:
1282:
1281:J. Biol. Chem
1278:
1273:
1269:
1265:
1260:
1255:
1252:(3): 477–84.
1251:
1247:
1243:
1238:
1234:
1230:
1225:
1220:
1216:
1212:
1208:
1204:
1200:
1195:
1191:
1187:
1182:
1177:
1173:
1169:
1165:
1161:
1157:
1152:
1148:
1144:
1139:
1134:
1130:
1126:
1122:
1118:
1114:
1109:
1108:
1103:
1094:
1088:
1085:
1080:
1076:
1072:
1068:
1064:
1060:
1052:
1049:
1044:
1040:
1034:
1031:
1026:
1022:
1016:
1013:
1009:
1005:
1000:
998:
996:
992:
988:
984:
979:
977:
975:
971:
964:
962:
960:
957:
953:
949:
937:
932:
928:
924:
921:
917:
910:
908:
905:
901:
897:
893:
890:
886:
882:
875:
873:
867:
863:
860:
854:
852:
846:
842:
839:
835:
828:
826:
820:
816:
813:
807:
805:
799:
795:
792:
790:RefSeq (mRNA)
788:
781:
780:
775:
771:
768:
762:
761:
756:
752:
749:
747:
743:
736:
735:
730:
726:
723:
717:
716:
711:
707:
704:
702:
698:
691:
690:
685:
681:
678:
672:
671:
666:
662:
659:
657:
653:
650:
647:
645:
642:
638:
635:
631:
627:
620:
616:
611:
605:
604:cornification
602:
600:
597:
595:
592:
590:
587:
585:
582:
581:
579:
576:
575:
569:
566:
564:
561:
559:
556:
555:
553:
550:
549:
543:
540:
538:
535:
534:
532:
529:
528:
525:
524:Gene ontology
521:
517:
505:
500:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
1620:expanding it
1612:chromosome 1
1605:
1590:
1556:
1552:
1513:
1509:
1478:
1474:
1435:
1431:
1382:
1378:
1329:
1325:
1284:
1280:
1249:
1245:
1206:
1202:
1163:
1159:
1120:
1116:
1087:
1065:(3): 630–7.
1062:
1058:
1051:
1042:
1033:
1024:
1015:
955:
947:
946:
869:
848:
822:
801:
777:
758:
732:
713:
687:
668:
648:
643:
435:skin of back
335:
328:
193:153,057,512
180:153,056,120
55:External IDs
18:
389:human penis
385:oral cavity
294:92,294,631
281:92,292,992
33:Identifiers
1659:Categories
1304:1887/50054
1246:Mol. Cells
1203:Genome Res
1010:, May 2017
989:, May 2017
965:References
451:belly cord
339:(ortholog)
76:HomoloGene
1610:on human
872:NP_035604
851:NP_005979
825:NM_011474
804:NM_005988
634:Orthologs
558:cytoplasm
459:esophagus
84:GeneCards
1419:10737800
1366:12477932
1313:12624109
1268:15232223
1233:15489334
1190:16639001
1147:16710414
1059:Genomics
1006:–
985:–
920:Wikidata
613:Sources:
423:gastrula
1583:2388825
1540:8816448
1497:8999895
1462:9826750
1387:Bibcode
1334:Bibcode
1181:2906387
1125:Bibcode
1079:8325635
1008:Ensembl
987:Ensembl
952:protein
746:UniProt
701:Ensembl
640:Species
619:QuickGO
568:cytosol
427:decidua
314:pattern
72:1330343
40:Aliases
1581:
1574:331257
1571:
1538:
1531:231535
1528:
1495:
1460:
1453:147987
1450:
1417:
1407:
1364:
1357:139241
1354:
1311:
1266:
1231:
1224:528928
1221:
1188:
1178:
1145:
1117:Nature
1077:
956:SPRR2A
906:search
904:PubMed
779:O70559
760:P35326
656:Entrez
485:BioGPS
431:cervix
172:1q21.3
88:SPRR2A
80:130544
64:182267
47:SPRR2A
24:SPRR2A
1614:is a
1410:16267
950:is a
689:20762
649:Mouse
644:Human
615:Amigo
397:vulva
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
1616:stub
1608:gene
1579:PMID
1536:PMID
1493:PMID
1458:PMID
1415:PMID
1362:PMID
1309:PMID
1264:PMID
1229:PMID
1186:PMID
1143:PMID
1075:PMID
959:gene
670:6700
365:gums
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
1569:PMC
1561:doi
1526:PMC
1518:doi
1483:doi
1479:272
1448:PMC
1440:doi
1405:PMC
1395:doi
1352:PMC
1342:doi
1299:hdl
1289:doi
1285:278
1254:doi
1219:PMC
1211:doi
1176:PMC
1168:doi
1133:doi
1121:441
1067:doi
439:lip
290:End
189:End
92:OMA
68:MGI
1661::
1577:.
1567:.
1557:18
1555:.
1551:.
1534:.
1524:.
1514:16
1512:.
1508:.
1491:.
1477:.
1473:.
1456:.
1446:.
1436:26
1434:.
1430:.
1413:.
1403:.
1393:.
1383:97
1381:.
1377:.
1360:.
1350:.
1340:.
1330:99
1328:.
1324:.
1307:.
1297:.
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1279:.
1262:.
1250:17
1248:.
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1227:.
1217:.
1207:14
1205:.
1201:.
1184:.
1174:.
1164:47
1162:.
1158:.
1141:.
1131:.
1119:.
1115:.
1073:.
1063:16
1061:.
1041:.
1023:.
994:^
973:^
961:.
617:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
1647:e
1640:t
1633:v
1622:.
1585:.
1563::
1542:.
1520::
1499:.
1485::
1464:.
1442::
1421:.
1397::
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1368:.
1344::
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1315:.
1301::
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1235:.
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1027:.
214:)
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