343:
320:
217:
242:
601:
594:
42:
349:
248:
2994:
1926:
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P,
68:
2417:
Iyer N, Reagan MS, Wu KJ, Canagarajah B, Friedberg EC (1996). "Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and
Cockayne syndrome group B (CSB) protein".
1927:
Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network".
2305:
Layfield R, Ciani B, Ralston SH, Hocking LJ, Sheppard PW, Searle MS, Cavey JR (2005). "Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone".
2374:"Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region"
2947:
Feng, Lifeng et al. “Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia” Theranostics vol. 7,7 1890-1900. 10 Apr. 2017, doi:10.7150/thno.19135
2253:
Feng, Lifeng et al. “Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia” Theranostics vol. 7,7 1890-1900. 10 Apr. 2017, doi:10.7150/thno.19135
356:
255:
2831:
Kuusisto E, Salminen A, Alafuzoff I (2001). "Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies".
2122:"Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling"
1099:
178:
1080:
1834:
Shvets E, Fass E, Scherz-Shouval R, Elazar Z (August 2008). "The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes".
2973:
1566:
1548:
3022:
342:
2993:
1705:
2911:
Chang S, Kim JH, Shin J (2002). "p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition".
1327:
1334:
319:
2519:"The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase"
1692:
1535:
1514:
3027:
2449:"p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins"
1781:"Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone"
2868:
Laurin N, Brown JP, Lemainque A, Duchesne A, Huot D, Lacourcière Y, Drapeau G, Verreault J, Raymond V, Morissette J (2001).
1531:
241:
216:
65:
1510:
2597:"Genomic structure and promoter analysis of the p62 gene encoding a non-proteasomal multiubiquitin chain binding protein"
158:
2683:"Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent"
1436:
355:
254:
2798:"The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor"
2078:"The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor"
1722:
1424:
348:
247:
2554:"Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62"
1879:"Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62"
2966:
1148:
166:
1645:"A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes"
1129:
1125:
2517:
Jallal B, Mossie K, Vasiloudis G, Knyazev P, Zachwieja J, Clairvoyant F, Schilling J, Ullrich A (1997).
2268:
Geetha T, Wooten MW (2002). "Structure and functional properties of the ubiquitin binding protein p62".
2959:
2343:
Michou L, Collet C, Laplanche JL, Orcel P, Cornélis F (2006). "Genetics of Paget's disease of bone".
1936:
1737:
1597:
230:
145:
1306:
1281:
1277:
1247:
1222:
1218:
2755:"The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway"
2213:
Wooten MW, Geetha T, Babu JR, Seibenhener ML, Peng J, Cox N, Diaz-Meco MT, Moscat J (March 2008).
2029:"The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway"
1643:
Devergne O, Hummel M, Koeppen H, Le Beau MM, Nathanson EC, Kieff E, Birkenbach M (February 1996).
2936:
2856:
2626:
2331:
2293:
2215:"Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins"
1960:
1859:
1816:
1761:
190:
1310:
1285:
1251:
1226:
600:
593:
2928:
2899:
2848:
2819:
2784:
2741:
2712:
2669:
2618:
2583:
2540:
2505:
2470:
2435:
2405:
2360:
2323:
2285:
2236:
2195:
2143:
2099:
2058:
2009:
1952:
1908:
1851:
1808:
1800:
1753:
1674:
1625:
138:
58:
2920:
2889:
2881:
2840:
2809:
2774:
2766:
2733:
2702:
2694:
2659:
2651:
2608:
2573:
2565:
2530:
2495:
2460:
2427:
2395:
2385:
2352:
2315:
2277:
2226:
2185:
2177:
2133:
2089:
2048:
2040:
1999:
1991:
1944:
1898:
1890:
1843:
1792:
1745:
1664:
1656:
1615:
1605:
435:
366:
310:
265:
186:
2681:
Stumptner C, Heid H, Fuchsbichler A, Hauser H, Mischinger HJ, Zatloukal K, Denk H (1999).
410:
2076:
Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J (March 2001).
1940:
1741:
1601:
41:
2894:
2869:
2707:
2682:
2664:
2639:
2190:
2165:
2004:
1979:
1779:
Layfield R, Ciani B, Ralston S, Hocking L, Sheppard P, Searle M, Cavey J (2004-10-26).
2924:
2779:
2754:
2698:
2613:
2596:
2578:
2553:
2281:
2053:
2028:
1903:
1878:
1669:
1644:
1014:
1009:
1004:
999:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
838:
833:
828:
823:
818:
813:
808:
803:
798:
793:
788:
783:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
712:
707:
702:
697:
692:
687:
682:
677:
672:
667:
662:
657:
652:
647:
642:
3016:
2844:
2400:
2373:
1620:
1585:
1405:
629:
2940:
2860:
2335:
2297:
1820:
1765:
1660:
1586:"Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain"
2796:
Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J (2001).
2724:
Sudo T, Maruyama M, Osada H (2000). "p62 functions as a p38 MAP kinase regulator".
2630:
1964:
1863:
428:
207:
170:
2640:"The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation"
2484:"A p56(lck) ligand serves as a coactivator of an orphan nuclear hormone receptor"
2356:
1980:"The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation"
194:
1571:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1553:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2655:
2181:
1995:
511:
2770:
2044:
1417:
327:
224:
174:
149:, A170, OSIL, PDB3, ZIP3, p60, p62, p62B, FTDALS3, Sequestosome 1, NADGP, DMRV
2535:
2518:
2500:
2483:
2465:
2448:
2390:
1804:
1749:
1610:
1511:
ENSG00000284099 GRCh38: Ensembl release 89: ENSG00000161011, ENSG00000284099
1409:
1044:
571:
449:
394:
381:
293:
280:
182:
2932:
2903:
2852:
2823:
2814:
2797:
2788:
2745:
2737:
2716:
2673:
2364:
2327:
2289:
2240:
2231:
2214:
2199:
2147:
2138:
2121:
2103:
2094:
2077:
2062:
2013:
1956:
1855:
1812:
1757:
2622:
2587:
2569:
2544:
2509:
2474:
2439:
2409:
1912:
1894:
1678:
1629:
1374:
1369:
1444:
1358:
1193:
1174:
1948:
1877:
Sanchez P, De Carcer G, Sandoval IV, Moscat J, Diaz-Meco MT (May 1998).
1408:
cargo protein that targets other proteins that bind to it for selective
2319:
1847:
1796:
1390:
1160:
1111:
2431:
115:
111:
107:
103:
99:
95:
91:
87:
17:
2166:"Identification of a consensus site for TRAF6/p62 polyubiquitination"
1780:
1456:
1342:
1066:
2552:
Sanchez P, De Carcer G, Sandoval IV, Moscat J, Diaz-Meco MT (1998).
2885:
1416:
and targeting it for degradation, it can inhibit GATA-4 associated
2870:"Paget disease of bone: mapping of two loci at 5q35-qter and 5q31"
1468:
1462:
1450:
1413:
1029:
1025:
2372:
Park I, Chung J, Walsh CT, Yun Y, Strominger JL, Shin J (1996).
1709:
1485:
1479:
1473:
1397:
162:
2955:
673:
K63-linked polyubiquitin modification-dependent protein binding
609:
2951:
2638:
Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J (1999).
1978:
Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J (1999).
1015:
positive regulation of protein localization to plasma membrane
950:
negative regulation of transcription by RNA polymerase II
945:
positive regulation of transcription by RNA polymerase II
2482:
Marcus SL, Winrow CJ, Capone JP, Rachubinski RA (1996).
418:
2027:
Sanz L, Diaz-Meco MT, Nakano H, Moscat J (April 2000).
980:
protein localization to perinuclear region of cytoplasm
1010:
positive regulation of long-term synaptic potentiation
2447:
Vadlamudi RK, Joung I, Strominger JL, Shin J (1996).
583:
1299:
1270:
1240:
1211:
522:
dentate gyrus of hippocampal formation granule cell
1527:
1525:
1523:
1506:
1504:
1502:
3002:: NMR structure of the UBA domain of p62 (SQSTM1)
2753:Sanz L, Diaz-Meco MT, Nakano H, Moscat J (2000).
940:regulation of I-kappaB kinase/NF-kappaB signaling
365:
264:
2164:Jadhav T, Geetha T, Jiang J, Wooten MW (2008).
2159:
2157:
2115:
2113:
1420:and senescence-associated secretory phenotype.
29:Protein-coding gene in the species Homo sapiens
1532:GRCm38: Ensembl release 89: ENSMUSG00000015837
870:positive regulation of protein phosphorylation
2967:
905:regulation of Ras protein signal transduction
880:ubiquitin-dependent protein catabolic process
8:
1584:Joung I, Strominger JL, Shin J (July 1996).
2974:
2960:
2952:
1423:Mutations in SQSTM1 are a common cause of
1040:
625:
406:
305:
202:
76:
2893:
2813:
2778:
2706:
2663:
2612:
2577:
2534:
2499:
2464:
2399:
2389:
2230:
2189:
2137:
2093:
2052:
2003:
1902:
1668:
1619:
1609:
1005:interleukin-1-mediated signaling pathway
965:response to mitochondrial depolarisation
935:positive regulation of apoptotic process
910:negative regulation of apoptotic process
885:regulation of mitochondrion organization
819:intracellular membrane-bounded organelle
668:protein serine/threonine kinase activity
2989:
1498:
925:regulation of protein complex stability
31:
2120:Geetha T, Wooten MW (February 2003).
713:ionotropic glutamate receptor binding
370:
331:
326:
269:
228:
223:
7:
1693:"Entrez Gene: SQSTM1 sequestosome 1"
1706:Online Mendelian Inheritance in Man
1296:
1267:
1237:
1208:
1184:
1165:
1139:
1116:
1090:
1071:
588:
554:central gray substance of midbrain
506:
444:
423:
25:
1435:Sequestosome 1 has been shown to
1393:that in humans is encoded by the
875:intracellular signal transduction
643:protein homodimerization activity
2992:
2845:10.1097/00001756-200107200-00009
1785:Biochemical Society Transactions
708:ubiquitin protein ligase binding
648:receptor tyrosine kinase binding
599:
592:
354:
347:
341:
318:
253:
246:
240:
215:
40:
1723:"GATA get a hold on senescence"
1661:10.1128/JVI.70.2.1143-1153.1996
610:More reference expression data
572:More reference expression data
1:
2925:10.1016/S0014-5793(01)03224-0
2726:Biochem. Biophys. Res. Commun
2699:10.1016/S0002-9440(10)65426-0
2614:10.1016/S0014-5793(98)01021-7
2595:Vadlamudi RK, Shin J (1998).
2282:10.1016/S0014-5793(02)02286-X
2170:Biochem. Biophys. Res. Commun
1721:Cassidy LD, Narita M (2015).
1402:ubiquitin-binding protein p62
890:protein heterooligomerization
339:
238:
2378:Proc. Natl. Acad. Sci. U.S.A
2357:10.1016/j.jbspin.2005.05.009
3023:Genes on human chromosome 5
480:right lobe of thyroid gland
472:stromal cell of endometrium
3044:
2182:10.1016/j.bbrc.2008.04.138
990:mitochondrion organization
930:autophagy of mitochondrion
558:sternocleidomastoid muscle
484:left lobe of thyroid gland
2987:
1567:"Mouse PubMed Reference:"
1549:"Human PubMed Reference:"
1373:
1368:
1364:
1357:
1341:
1328:Chr 5: 179.81 – 179.84 Mb
1322:
1303:
1274:
1263:
1244:
1215:
1204:
1191:
1187:
1172:
1168:
1159:
1146:
1142:
1123:
1119:
1110:
1097:
1093:
1078:
1074:
1065:
1050:
1043:
1039:
1023:
683:identical protein binding
628:
624:
607:
591:
582:
569:
518:
509:
496:Descending thoracic aorta
456:
447:
417:
409:
405:
388:
375:
338:
317:
308:
304:
287:
274:
237:
214:
205:
201:
156:
153:
143:
136:
131:
84:
79:
62:
57:
52:
48:
39:
34:
2656:10.1093/emboj/18.11.3044
2536:10.1074/jbc.272.18.12158
2501:10.1074/jbc.271.44.27197
2466:10.1074/jbc.271.34.20235
2391:10.1073/pnas.92.26.12338
1996:10.1093/emboj/18.11.3044
1590:Proc Natl Acad Sci U S A
754:phagophore assembly site
693:protein kinase C binding
2771:10.1093/emboj/19.7.1576
2045:10.1093/emboj/19.7.1576
1750:10.1126/science.aad2501
1611:10.1073/pnas.93.12.5991
1425:Paget's disease of bone
1412:. By interacting with
1335:Chr 11: 50.09 – 50.1 Mb
955:protein phosphorylation
2815:10.1074/jbc.C000869200
2738:10.1006/bbrc.2000.2333
2232:10.1074/jbc.M709496200
2139:10.1074/jbc.M208468200
2095:10.1074/jbc.C000869200
688:protein kinase binding
546:superior frontal gyrus
534:triceps brachii muscle
3028:Genes mutated in mice
2570:10.1128/mcb.18.5.3069
1895:10.1128/mcb.18.5.3069
1400:. Also known as the
975:endosome organization
895:immune system process
799:extracellular exosome
779:endoplasmic reticulum
333:Chromosome 11 (mouse)
985:response to ischemia
865:cell differentiation
860:protein localization
542:ventromedial nucleus
460:right adrenal cortex
231:Chromosome 5 (human)
80:List of PDB id codes
53:Available structures
2308:Biochem. Soc. Trans
1949:10.1038/nature04209
1941:2005Natur.437.1173R
1742:2015Sci...349.1448C
1602:1996PNAS...93.5991J
1000:selective autophagy
920:endosomal transport
804:cytoplasmic vesicle
468:left adrenal cortex
2320:10.1042/BST0320728
1848:10.1242/jcs.026005
1842:(Pt 16): 2685–95.
1797:10.1042/bst0320728
1149:ENSMUSG00000015837
900:response to stress
848:Biological process
722:Cellular component
658:SH2 domain binding
636:Molecular function
464:left adrenal gland
195:SQSTM1 - orthologs
3010:
3009:
2874:Am. J. Hum. Genet
2494:(44): 27197–200.
2432:10.1021/bi9524124
1384:
1383:
1380:
1379:
1353:
1352:
1318:
1317:
1293:
1292:
1259:
1258:
1234:
1233:
1200:
1199:
1181:
1180:
1155:
1154:
1136:
1135:
1106:
1105:
1087:
1086:
1035:
1034:
855:apoptotic process
698:ubiquitin binding
663:metal ion binding
620:
619:
616:
615:
578:
577:
565:
564:
503:
502:
401:
400:
300:
299:
127:
126:
123:
122:
63:Ortholog search:
16:(Redirected from
3035:
2996:
2976:
2969:
2962:
2953:
2944:
2907:
2897:
2864:
2827:
2817:
2792:
2782:
2749:
2720:
2710:
2677:
2667:
2634:
2616:
2591:
2581:
2548:
2538:
2529:(18): 12158–63.
2513:
2503:
2478:
2468:
2443:
2413:
2403:
2393:
2384:(26): 12338–42.
2368:
2345:Joint Bone Spine
2339:
2314:(Pt 5): 728–30.
2301:
2254:
2251:
2245:
2244:
2234:
2210:
2204:
2203:
2193:
2161:
2152:
2151:
2141:
2117:
2108:
2107:
2097:
2073:
2067:
2066:
2056:
2024:
2018:
2017:
2007:
1975:
1969:
1968:
1935:(7062): 1173–8.
1923:
1917:
1916:
1906:
1874:
1868:
1867:
1831:
1825:
1824:
1776:
1770:
1769:
1736:(6255): 1448–9.
1727:
1718:
1712:
1703:
1697:
1696:
1689:
1683:
1682:
1672:
1640:
1634:
1633:
1623:
1613:
1581:
1575:
1574:
1563:
1557:
1556:
1545:
1539:
1529:
1518:
1508:
1366:
1365:
1337:
1330:
1313:
1297:
1288:
1268:
1264:RefSeq (protein)
1254:
1238:
1229:
1209:
1185:
1166:
1140:
1117:
1091:
1072:
1041:
653:zinc ion binding
626:
612:
603:
596:
589:
574:
514:
512:Top expressed in
507:
452:
450:Top expressed in
445:
424:
407:
397:
384:
373:
358:
351:
345:
334:
322:
306:
296:
283:
272:
257:
250:
244:
233:
219:
203:
197:
148:
141:
118:
77:
71:
50:
49:
44:
32:
21:
3043:
3042:
3038:
3037:
3036:
3034:
3033:
3032:
3013:
3012:
3011:
3006:
3003:
2997:
2983:
2980:
2950:
2910:
2867:
2839:(10): 2085–90.
2830:
2808:(11): 7709–12.
2795:
2752:
2723:
2680:
2650:(11): 3044–53.
2637:
2607:(2–3): 138–42.
2594:
2558:Mol. Cell. Biol
2551:
2516:
2481:
2459:(34): 20235–7.
2446:
2416:
2371:
2342:
2304:
2267:
2263:
2261:Further reading
2258:
2257:
2252:
2248:
2212:
2211:
2207:
2163:
2162:
2155:
2119:
2118:
2111:
2088:(11): 7709–12.
2075:
2074:
2070:
2026:
2025:
2021:
1990:(11): 3044–53.
1977:
1976:
1972:
1925:
1924:
1920:
1883:Mol. Cell. Biol
1876:
1875:
1871:
1833:
1832:
1828:
1778:
1777:
1773:
1725:
1720:
1719:
1715:
1704:
1700:
1691:
1690:
1686:
1642:
1641:
1637:
1583:
1582:
1578:
1565:
1564:
1560:
1547:
1546:
1542:
1530:
1521:
1509:
1500:
1495:
1490:
1433:
1375:View/Edit Mouse
1370:View/Edit Human
1333:
1326:
1323:Location (UCSC)
1309:
1305:
1284:
1280:
1276:
1250:
1246:
1225:
1221:
1217:
1130:ENSG00000284099
1128:
1126:ENSG00000161011
1019:
843:
717:
678:protein binding
608:
598:
597:
570:
561:
556:
552:
550:temporal muscle
548:
544:
540:
536:
532:
528:
526:muscle of thigh
524:
510:
499:
494:
490:
486:
482:
478:
476:muscle of thigh
474:
470:
466:
462:
448:
392:
379:
372:11|11 B1.3
371:
361:
360:
359:
352:
332:
309:Gene location (
291:
278:
270:
260:
259:
258:
251:
229:
206:Gene location (
157:
144:
137:
86:
64:
30:
23:
22:
15:
12:
11:
5:
3041:
3039:
3031:
3030:
3025:
3015:
3014:
3008:
3007:
3005:
3004:
2998:
2991:
2988:
2985:
2984:
2981:
2979:
2978:
2971:
2964:
2956:
2949:
2948:
2945:
2919:(1–2): 57–61.
2908:
2886:10.1086/322975
2865:
2828:
2793:
2765:(7): 1576–86.
2750:
2721:
2693:(6): 1701–10.
2678:
2635:
2592:
2564:(5): 3069–80.
2549:
2514:
2479:
2444:
2426:(7): 2157–67.
2414:
2369:
2340:
2302:
2276:(1–3): 19–24.
2264:
2262:
2259:
2256:
2255:
2246:
2225:(11): 6783–9.
2205:
2153:
2109:
2068:
2039:(7): 1576–86.
2019:
1970:
1918:
1889:(5): 3069–80.
1869:
1826:
1791:(5): 728–730.
1771:
1713:
1698:
1684:
1655:(2): 1143–53.
1635:
1596:(12): 5991–5.
1576:
1558:
1540:
1519:
1497:
1496:
1494:
1491:
1489:
1488:
1483:
1477:
1471:
1466:
1460:
1454:
1448:
1441:
1432:
1429:
1387:Sequestosome-1
1382:
1381:
1378:
1377:
1372:
1362:
1361:
1355:
1354:
1351:
1350:
1348:
1346:
1339:
1338:
1331:
1324:
1320:
1319:
1316:
1315:
1301:
1300:
1294:
1291:
1290:
1272:
1271:
1265:
1261:
1260:
1257:
1256:
1242:
1241:
1235:
1232:
1231:
1213:
1212:
1206:
1202:
1201:
1198:
1197:
1189:
1188:
1182:
1179:
1178:
1170:
1169:
1163:
1157:
1156:
1153:
1152:
1144:
1143:
1137:
1134:
1133:
1121:
1120:
1114:
1108:
1107:
1104:
1103:
1095:
1094:
1088:
1085:
1084:
1076:
1075:
1069:
1063:
1062:
1057:
1052:
1048:
1047:
1037:
1036:
1033:
1032:
1021:
1020:
1018:
1017:
1012:
1007:
1002:
997:
992:
987:
982:
977:
972:
970:macroautophagy
967:
962:
957:
952:
947:
942:
937:
932:
927:
922:
917:
912:
907:
902:
897:
892:
887:
882:
877:
872:
867:
862:
857:
851:
849:
845:
844:
842:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
794:sperm midpiece
791:
786:
784:inclusion body
781:
776:
771:
766:
761:
756:
751:
746:
741:
736:
731:
725:
723:
719:
718:
716:
715:
710:
705:
703:enzyme binding
700:
695:
690:
685:
680:
675:
670:
665:
660:
655:
650:
645:
639:
637:
633:
632:
622:
621:
618:
617:
614:
613:
605:
604:
586:
580:
579:
576:
575:
567:
566:
563:
562:
560:
559:
555:
551:
547:
543:
539:
535:
531:
527:
523:
519:
516:
515:
504:
501:
500:
498:
497:
493:
492:gastric mucosa
489:
485:
481:
477:
473:
469:
465:
461:
457:
454:
453:
441:
440:
432:
421:
415:
414:
411:RNA expression
403:
402:
399:
398:
390:
386:
385:
377:
374:
369:
363:
362:
353:
346:
340:
336:
335:
330:
324:
323:
315:
314:
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
227:
221:
220:
212:
211:
199:
198:
155:
151:
150:
142:
134:
133:
129:
128:
125:
124:
121:
120:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
28:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3040:
3029:
3026:
3024:
3021:
3020:
3018:
3001:
2995:
2990:
2986:
2977:
2972:
2970:
2965:
2963:
2958:
2957:
2954:
2946:
2942:
2938:
2934:
2930:
2926:
2922:
2918:
2914:
2909:
2905:
2901:
2896:
2891:
2887:
2883:
2880:(3): 528–43.
2879:
2875:
2871:
2866:
2862:
2858:
2854:
2850:
2846:
2842:
2838:
2834:
2829:
2825:
2821:
2816:
2811:
2807:
2803:
2802:J. Biol. Chem
2799:
2794:
2790:
2786:
2781:
2776:
2772:
2768:
2764:
2760:
2756:
2751:
2747:
2743:
2739:
2735:
2731:
2727:
2722:
2718:
2714:
2709:
2704:
2700:
2696:
2692:
2688:
2687:Am. J. Pathol
2684:
2679:
2675:
2671:
2666:
2661:
2657:
2653:
2649:
2645:
2641:
2636:
2632:
2628:
2624:
2620:
2615:
2610:
2606:
2602:
2598:
2593:
2589:
2585:
2580:
2575:
2571:
2567:
2563:
2559:
2555:
2550:
2546:
2542:
2537:
2532:
2528:
2524:
2523:J. Biol. Chem
2520:
2515:
2511:
2507:
2502:
2497:
2493:
2489:
2488:J. Biol. Chem
2485:
2480:
2476:
2472:
2467:
2462:
2458:
2454:
2453:J. Biol. Chem
2450:
2445:
2441:
2437:
2433:
2429:
2425:
2421:
2415:
2411:
2407:
2402:
2397:
2392:
2387:
2383:
2379:
2375:
2370:
2366:
2362:
2358:
2354:
2350:
2346:
2341:
2337:
2333:
2329:
2325:
2321:
2317:
2313:
2309:
2303:
2299:
2295:
2291:
2287:
2283:
2279:
2275:
2271:
2266:
2265:
2260:
2250:
2247:
2242:
2238:
2233:
2228:
2224:
2220:
2219:J. Biol. Chem
2216:
2209:
2206:
2201:
2197:
2192:
2187:
2183:
2179:
2175:
2171:
2167:
2160:
2158:
2154:
2149:
2145:
2140:
2135:
2132:(7): 4730–9.
2131:
2127:
2126:J. Biol. Chem
2123:
2116:
2114:
2110:
2105:
2101:
2096:
2091:
2087:
2083:
2082:J. Biol. Chem
2079:
2072:
2069:
2064:
2060:
2055:
2050:
2046:
2042:
2038:
2034:
2030:
2023:
2020:
2015:
2011:
2006:
2001:
1997:
1993:
1989:
1985:
1981:
1974:
1971:
1966:
1962:
1958:
1954:
1950:
1946:
1942:
1938:
1934:
1930:
1922:
1919:
1914:
1910:
1905:
1900:
1896:
1892:
1888:
1884:
1880:
1873:
1870:
1865:
1861:
1857:
1853:
1849:
1845:
1841:
1837:
1830:
1827:
1822:
1818:
1814:
1810:
1806:
1802:
1798:
1794:
1790:
1786:
1782:
1775:
1772:
1767:
1763:
1759:
1755:
1751:
1747:
1743:
1739:
1735:
1731:
1724:
1717:
1714:
1711:
1707:
1702:
1699:
1694:
1688:
1685:
1680:
1676:
1671:
1666:
1662:
1658:
1654:
1650:
1646:
1639:
1636:
1631:
1627:
1622:
1617:
1612:
1607:
1603:
1599:
1595:
1591:
1587:
1580:
1577:
1572:
1568:
1562:
1559:
1554:
1550:
1544:
1541:
1537:
1533:
1528:
1526:
1524:
1520:
1516:
1512:
1507:
1505:
1503:
1499:
1492:
1487:
1484:
1481:
1478:
1475:
1472:
1470:
1467:
1464:
1461:
1458:
1455:
1452:
1449:
1446:
1443:
1442:
1440:
1438:
1430:
1428:
1426:
1421:
1419:
1415:
1411:
1407:
1406:autophagosome
1403:
1399:
1396:
1392:
1388:
1376:
1371:
1367:
1363:
1360:
1356:
1349:
1347:
1344:
1340:
1336:
1332:
1329:
1325:
1321:
1314:
1312:
1308:
1302:
1298:
1295:
1289:
1287:
1283:
1279:
1273:
1269:
1266:
1262:
1255:
1253:
1249:
1243:
1239:
1236:
1230:
1228:
1224:
1220:
1214:
1210:
1207:
1205:RefSeq (mRNA)
1203:
1196:
1195:
1190:
1186:
1183:
1177:
1176:
1171:
1167:
1164:
1162:
1158:
1151:
1150:
1145:
1141:
1138:
1132:
1131:
1127:
1122:
1118:
1115:
1113:
1109:
1102:
1101:
1096:
1092:
1089:
1083:
1082:
1077:
1073:
1070:
1068:
1064:
1061:
1058:
1056:
1053:
1049:
1046:
1042:
1038:
1031:
1027:
1022:
1016:
1013:
1011:
1008:
1006:
1003:
1001:
998:
996:
993:
991:
988:
986:
983:
981:
978:
976:
973:
971:
968:
966:
963:
961:
958:
956:
953:
951:
948:
946:
943:
941:
938:
936:
933:
931:
928:
926:
923:
921:
918:
916:
913:
911:
908:
906:
903:
901:
898:
896:
893:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
866:
863:
861:
858:
856:
853:
852:
850:
847:
846:
840:
837:
835:
832:
830:
829:mitochondrion
827:
825:
822:
820:
817:
815:
812:
810:
807:
805:
802:
800:
797:
795:
792:
790:
787:
785:
782:
780:
777:
775:
772:
770:
769:autophagosome
767:
765:
762:
760:
757:
755:
752:
750:
747:
745:
744:late endosome
742:
740:
737:
735:
732:
730:
727:
726:
724:
721:
720:
714:
711:
709:
706:
704:
701:
699:
696:
694:
691:
689:
686:
684:
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
640:
638:
635:
634:
631:
630:Gene ontology
627:
623:
611:
606:
602:
595:
590:
587:
585:
581:
573:
568:
557:
553:
549:
545:
541:
538:adrenal gland
537:
533:
529:
525:
521:
520:
517:
513:
508:
505:
495:
491:
487:
483:
479:
475:
471:
467:
463:
459:
458:
455:
451:
446:
443:
442:
439:
437:
433:
431:
430:
426:
425:
422:
420:
416:
412:
408:
404:
396:
391:
387:
383:
378:
368:
364:
357:
350:
344:
337:
329:
325:
321:
316:
312:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
232:
226:
222:
218:
213:
209:
204:
200:
196:
192:
188:
184:
180:
176:
172:
168:
164:
160:
152:
147:
140:
135:
130:
119:
117:
113:
109:
105:
101:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
27:
19:
2999:
2916:
2912:
2877:
2873:
2836:
2832:
2805:
2801:
2762:
2758:
2732:(2): 521–5.
2729:
2725:
2690:
2686:
2647:
2643:
2604:
2600:
2561:
2557:
2526:
2522:
2491:
2487:
2456:
2452:
2423:
2420:Biochemistry
2419:
2381:
2377:
2351:(3): 243–8.
2348:
2344:
2311:
2307:
2273:
2269:
2249:
2222:
2218:
2208:
2176:(3): 521–4.
2173:
2169:
2129:
2125:
2085:
2081:
2071:
2036:
2032:
2022:
1987:
1983:
1973:
1932:
1928:
1921:
1886:
1882:
1872:
1839:
1835:
1829:
1788:
1784:
1774:
1733:
1729:
1716:
1701:
1687:
1652:
1648:
1638:
1593:
1589:
1579:
1570:
1561:
1552:
1543:
1434:
1431:Interactions
1422:
1401:
1394:
1386:
1385:
1307:NP_001277698
1304:
1282:NP_001135771
1278:NP_001135770
1275:
1248:NM_001290769
1245:
1223:NM_001142299
1219:NM_001142298
1216:
1192:
1173:
1147:
1124:
1098:
1079:
1059:
1054:
824:autolysosome
530:right kidney
434:
427:
292:179,838,078
279:179,806,398
154:External IDs
85:
26:
2982:PDB gallery
2833:NeuroReport
1836:J. Cell Sci
1404:, it is an
759:nucleoplasm
488:gallbladder
393:50,101,654
380:50,090,193
132:Identifiers
3017:Categories
1538:, May 2017
1517:, May 2017
1493:References
1418:senescence
995:aggrephagy
438:(ortholog)
175:HomoloGene
2913:FEBS Lett
2601:FEBS Lett
2270:FEBS Lett
1805:0300-5127
1410:autophagy
1311:NP_035148
1286:NP_003891
1252:NM_011018
1227:NM_003900
1045:Orthologs
960:mitophagy
915:autophagy
839:Lewy body
834:sarcomere
774:amphisome
764:aggresome
729:cytoplasm
183:GeneCards
2941:85579338
2933:11755531
2904:11473345
2861:21272705
2853:11447312
2824:11244088
2789:10747026
2746:10708586
2717:10362795
2674:10356400
2365:16574459
2336:22544044
2328:15493999
2298:22029085
2290:11852044
2241:18174161
2200:18457658
2148:12471037
2104:11244088
2063:10747026
2014:10356400
1957:16189514
1856:18653543
1821:22544044
1813:15493999
1766:35805331
1758:26404812
1708:(OMIM):
1534:–
1513:–
1445:MAP1LC3A
1437:interact
1359:Wikidata
1024:Sources:
789:lysosome
739:PML body
734:endosome
2895:1235483
2708:1866621
2665:1171386
2631:3184369
2623:9762895
2588:9566925
2545:9115287
2510:8910285
2475:8702753
2440:8652557
2410:8618896
2191:2474794
2005:1171386
1965:4427026
1937:Bibcode
1913:9566925
1864:2782335
1738:Bibcode
1730:Science
1679:8551575
1649:J Virol
1630:8650207
1598:Bibcode
1536:Ensembl
1515:Ensembl
1391:protein
1161:UniProt
1112:Ensembl
1051:Species
1030:QuickGO
814:cytosol
809:nucleus
413:pattern
139:Aliases
2939:
2931:
2902:
2892:
2859:
2851:
2822:
2787:
2780:310227
2777:
2759:EMBO J
2744:
2715:
2705:
2672:
2662:
2644:EMBO J
2629:
2621:
2586:
2579:110686
2576:
2543:
2508:
2473:
2438:
2408:
2398:
2363:
2334:
2326:
2296:
2288:
2239:
2198:
2188:
2146:
2102:
2061:
2054:310227
2051:
2033:EMBO J
2012:
2002:
1984:EMBO J
1963:
1955:
1929:Nature
1911:
1904:110686
1901:
1862:
1854:
1819:
1811:
1803:
1764:
1756:
1710:601530
1677:
1670:189923
1667:
1628:
1618:
1476:, and
1457:RAD23A
1439:with:
1395:SQSTM1
1345:search
1343:PubMed
1194:Q64337
1175:Q13501
1067:Entrez
749:P-body
584:BioGPS
271:5q35.3
187:SQSTM1
171:107931
163:601530
146:SQSTM1
35:SQSTM1
18:SQSTM1
2937:S2CID
2857:S2CID
2627:S2CID
2401:40352
2332:S2CID
2294:S2CID
1961:S2CID
1860:S2CID
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