303:
280:
1217:), generates deltaKASH1 isoforms terminating with a distinct 11-amino acid tail (GIAGHSATPPA replacing YPMLRYTNGPPPT in isoforms with KASH). Utilization of an alternative stop codon in exon 115, which is followed by a distinct 3' UTR, generates deltaKASH2 variants. This mechanism truncates larger isoforms without generating a distinct C-terminal sequence. Expression of deltaKASH1 variants occurs largely in brain and kidney, with smaller amounts in heart; deltaKASH2 variants are detected in heart and spleen.
1213:
allow translation of smaller isoforms, many possessing unique N- or C-terminal sequences encoded by retained introns. Two mechanisms create splice variants of nesprin-2 with the KASH domain deleted (deltaKASH). In deltaKASH1 variants, deletion of cassette exons 111-112 results in a frame shift that disrupts the KASH domain but retains the 3' untranslated region (UTR) in exon 116 utilized for isoforms containing the KASH domain. This mechanism, which also occurs in SYNE1 mRNA encoding nesprin-1 (
177:
202:
554:
309:
208:
2133:
1212:
The human SYNE2 gene encodes a protein of 6,885 amino acids (isoform 1, Nesp2 giant); alternative mRNA splicing produces transcripts encoding a larger isoform and numerous smaller isoforms, some of which are specific to various tissues; alternative start and termination sites within the mRNA also
52:
1201:) family. Nesprins are modular proteins with a central extended spectrin-repeat (SR) rod domain and a C-terminal Klarsicht/ANC-1/Syne homology (KASH) transmembrane domain, which acts as a NE-targeting motif. Nesprin-2 (Nesp2) binds to cytoplasmic
2096:
Wheeler MA, Davies JD, Zhang Q, et al. (2007). "Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery–Dreifuss muscular dystrophy".
316:
215:
1314:"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro"
1612:
Zhang Q, Ragnauth C, Greener MJ, et al. (2003). "The nesprins are giant actin-binding proteins, orthologous to
Drosophila melanogaster muscle protein MSP-300".
892:
873:
138:
2202:
2020:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
2178:
1862:"Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle"
1737:
Schirmer EC, Florens L, Guan T, et al. (2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics".
1294:
2197:
1276:
302:
1120:
1127:
279:
1394:
1895:
Cheng J, Kapranov P, Drenkow J, et al. (2005). "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution".
1263:
1242:
201:
176:
1259:
1552:"Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues"
49:
1583:
Zhen YY, Libotte T, Munck M, et al. (2003). "NUANCE, a giant protein connecting the nucleus and actin cytoskeleton".
1238:
1509:"Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs"
118:
315:
214:
1312:
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999).
2171:
1355:"Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction"
109:, EDMD5, NUA, NUANCE, Nesp2, Nesprin-2, SYNE-2, TROPH, spectrin repeat containing nuclear envelope protein 2, KASH2
308:
207:
937:
126:
1819:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
918:
1410:"Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds"
2164:
190:
1474:"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones"
1985:"The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope"
1904:
1746:
1707:
1654:
1421:
105:
1103:
1044:
1928:
1770:
150:
1643:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1082:
1078:
1074:
1070:
1023:
1019:
1015:
1011:
1007:
2114:
2084:
2049:
2006:
1971:
1920:
1883:
1848:
1805:
1762:
1725:
1682:
1629:
1600:
1571:
1538:
1495:
1449:
1376:
1335:
553:
98:
42:
2148:
2106:
2074:
2039:
2031:
1996:
1961:
1953:
1912:
1873:
1838:
1830:
1795:
1754:
1715:
1672:
1662:
1621:
1592:
1563:
1528:
1520:
1485:
1439:
1429:
1366:
1325:
395:
326:
270:
225:
1942:"Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope"
146:
370:
1908:
1750:
1711:
1658:
1425:
2044:
2019:
1966:
1941:
1444:
1409:
798:
nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration
1843:
1818:
1677:
1642:
1625:
1533:
1508:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
741:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
621:
605:
600:
595:
2191:
2144:
582:
1932:
1774:
1551:
130:
2063:"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks"
1206:
388:
167:
1434:
154:
2110:
1299:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1281:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2079:
2062:
471:
1197:
and encodes nesprin-2, a member of the nuclear envelope (NE) spectrin-repeat (
287:
184:
134:
1957:
1916:
1784:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1758:
1596:
1567:
1490:
1473:
1330:
1313:
837:
531:
409:
354:
341:
253:
240:
142:
2118:
2088:
2053:
2010:
1975:
1924:
1887:
1852:
1809:
1766:
1729:
1686:
1667:
1633:
1604:
1575:
1542:
1499:
1453:
1380:
1371:
1354:
1339:
1167:
1162:
1151:
982:
963:
1720:
1695:
2035:
1834:
1524:
1214:
1202:
1198:
1183:
949:
904:
2001:
1984:
1878:
1861:
75:
71:
1135:
859:
2132:
1800:
1783:
1395:"Entrez Gene: SYNE2 spectrin repeat containing, nuclear envelope 2"
822:
818:
2140:
1408:
Rajgor D, Mellad JA, Autore F, Zhang Q, Shanahan CM (Jul 2012).
1194:
1190:
562:
122:
1641:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1209:
and maintaining the structural integrity of the nucleus.
1507:
Wiemann S, Weil B, Wellenreuther R, et al. (2001).
378:
2152:
1817:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1472:
Nakajima D, Okazaki N, Yamakawa H, et al. (2003).
1860:
Zhang Q, Ragnauth CD, Skepper JN, et al. (2005).
1696:"The DNA sequence and analysis of human chromosome 14"
687:
meiotic nuclear membrane microtubule tethering complex
2018:
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
1694:
Heilig R, Eckenberg R, Petit JL, et al. (2003).
543:
1983:
Padmakumar VC, Libotte T, Lu W, et al. (2005).
1096:
1063:
1037:
1000:
1940:Libotte T, Zaim H, Abraham S, et al. (2005).
1782:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1353:Apel ED, Lewis RM, Grady RM, Sanes JR (Nov 2000).
1255:
1253:
1251:
1234:
1232:
1230:
2061:Olsen JV, Blagoev B, Gnad F, et al. (2006).
1550:Zhang Q, Skepper JN, Yang F, et al. (2002).
325:
224:
18:Protein-coding gene in the species Homo sapiens
1260:GRCm38: Ensembl release 89: ENSMUSG00000063450
2172:
788:establishment or maintenance of cell polarity
8:
1239:GRCh38: Ensembl release 89: ENSG00000054654
2179:
2165:
833:
578:
432:Skeletal muscle tissue of rectus abdominis
366:
265:
162:
60:
2078:
2043:
2000:
1965:
1877:
1842:
1799:
1719:
1676:
1666:
1532:
1489:
1443:
1433:
1370:
1329:
424:Skeletal muscle tissue of biceps brachii
1226:
1193:. The human SYNE2 gene consists of 116
20:
773:positive regulation of cell migration
768:nuclear migration along microfilament
330:
291:
286:
229:
188:
183:
7:
2129:
2127:
2151:. You can help Knowledge (XXG) by
1093:
1060:
1034:
997:
973:
954:
928:
909:
883:
864:
702:intermediate filament cytoskeleton
548:
466:
404:
383:
14:
1186:that in humans is encoded by the
2131:
552:
314:
307:
301:
278:
213:
206:
200:
175:
1205:, tethering the nucleus to the
793:protein localization to nucleus
697:sarcoplasmic reticulum membrane
2203:Human chromosome 14 gene stubs
627:integral component of membrane
563:More reference expression data
532:More reference expression data
1:
1626:10.1016/S0888-7543(02)96859-X
803:regulation of cilium assembly
763:nuclear envelope organization
299:
198:
2198:Genes on human chromosome 14
1647:Proc. Natl. Acad. Sci. U.S.A
1435:10.1371/journal.pone.0040098
808:centriole-centriole cohesion
2111:10.1016/j.yexcr.2007.03.025
2219:
2126:
2080:10.1016/j.cell.2006.09.026
1295:"Mouse PubMed Reference:"
1277:"Human PubMed Reference:"
1166:
1161:
1157:
1150:
1134:
1115:
1100:
1067:
1056:
1041:
1004:
993:
980:
976:
961:
957:
948:
935:
931:
916:
912:
903:
890:
886:
871:
867:
858:
843:
836:
832:
816:
581:
577:
560:
551:
542:
529:
478:
469:
416:
407:
377:
369:
365:
348:
335:
298:
277:
268:
264:
247:
234:
197:
174:
165:
161:
116:
113:
103:
96:
91:
68:
63:
46:
41:
36:
32:
28:
23:
1128:Chr 12: 75.86 – 76.16 Mb
1121:Chr 14: 63.76 – 64.23 Mb
498:Rostral migratory stream
1958:10.1091/mbc.E04-11-1009
1917:10.1126/science.1108625
1759:10.1126/science.1088176
1597:10.1242/jcs.115.15.3207
1568:10.1242/jcs.114.24.4485
778:centrosome localization
1668:10.1073/pnas.242603899
1372:10.1074/jbc.M004775200
722:lamellipodium membrane
717:nuclear outer membrane
657:sarcoplasmic reticulum
596:actin filament binding
494:neural layer of retina
436:triceps brachii muscle
332:12 C3|12 33.11 cM
1491:10.1093/dnares/9.3.99
1331:10.1093/dnares/6.1.63
712:extracellular exosome
293:Chromosome 12 (mouse)
191:Chromosome 14 (human)
758:fibroblast migration
64:List of PDB id codes
37:Available structures
1909:2005Sci...308.1149C
1751:2003Sci...301.1380S
1721:10.1038/nature01348
1712:2003Natur.421..601H
1659:2002PNAS...9916899M
1426:2012PLoSO...740098R
737:filopodium membrane
514:ganglionic eminence
452:epithelium of colon
428:ganglionic eminence
2139:This article on a
2036:10.1101/gr.4039406
1995:(Pt 15): 3419–30.
1835:10.1101/gr.2596504
1591:(Pt 15): 3207–22.
1562:(Pt 24): 4485–98.
1525:10.1101/gr.GR1547R
938:ENSMUSG00000063450
751:Biological process
615:Cellular component
589:Molecular function
444:thoracic diaphragm
2160:
2159:
2002:10.1242/jcs.02471
1903:(5725): 1149–54.
1879:10.1242/jcs.01642
1653:(26): 16899–903.
1177:
1176:
1173:
1172:
1146:
1145:
1111:
1110:
1090:
1089:
1052:
1051:
1031:
1030:
989:
988:
970:
969:
944:
943:
925:
924:
899:
898:
880:
879:
828:
827:
783:nuclear migration
573:
572:
569:
568:
538:
537:
525:
524:
463:
462:
361:
360:
260:
259:
155:SYNE2 - orthologs
87:
86:
83:
82:
47:Ortholog search:
2210:
2181:
2174:
2167:
2135:
2128:
2122:
2092:
2082:
2057:
2047:
2014:
2004:
1979:
1969:
1936:
1891:
1881:
1872:(Pt 4): 673–87.
1856:
1846:
1813:
1803:
1778:
1745:(5638): 1380–2.
1733:
1723:
1690:
1680:
1670:
1637:
1608:
1579:
1546:
1536:
1503:
1493:
1458:
1457:
1447:
1437:
1405:
1399:
1398:
1391:
1385:
1384:
1374:
1365:(41): 31986–95.
1350:
1344:
1343:
1333:
1309:
1303:
1302:
1291:
1285:
1284:
1273:
1267:
1257:
1246:
1236:
1159:
1158:
1130:
1123:
1106:
1094:
1085:
1061:
1057:RefSeq (protein)
1047:
1035:
1026:
998:
974:
955:
929:
910:
884:
865:
834:
637:nuclear envelope
632:nuclear membrane
579:
565:
556:
549:
534:
506:genital tubercle
490:secondary oocyte
482:ventricular zone
474:
472:Top expressed in
467:
420:ventricular zone
412:
410:Top expressed in
405:
384:
367:
357:
344:
333:
318:
311:
305:
294:
282:
266:
256:
243:
232:
217:
210:
204:
193:
179:
163:
157:
108:
101:
78:
61:
55:
34:
33:
21:
2218:
2217:
2213:
2212:
2211:
2209:
2208:
2207:
2188:
2187:
2186:
2185:
2125:
2105:(13): 2845–57.
2095:
2060:
2017:
1982:
1946:Mol. Biol. Cell
1939:
1894:
1859:
1829:(10B): 2121–7.
1816:
1781:
1736:
1706:(6923): 601–7.
1693:
1640:
1611:
1582:
1549:
1506:
1471:
1467:
1465:Further reading
1462:
1461:
1407:
1406:
1402:
1393:
1392:
1388:
1352:
1351:
1347:
1311:
1310:
1306:
1293:
1292:
1288:
1275:
1274:
1270:
1258:
1249:
1237:
1228:
1223:
1168:View/Edit Mouse
1163:View/Edit Human
1126:
1119:
1116:Location (UCSC)
1102:
1081:
1077:
1073:
1069:
1043:
1022:
1018:
1014:
1010:
1006:
919:ENSG00000054654
812:
746:
652:plasma membrane
610:
601:protein binding
561:
530:
521:
516:
512:
508:
504:
500:
496:
492:
488:
484:
470:
459:
454:
450:
446:
442:
438:
434:
430:
426:
422:
408:
352:
339:
331:
321:
320:
319:
312:
292:
269:Gene location (
251:
238:
230:
220:
219:
218:
211:
189:
166:Gene location (
117:
104:
97:
70:
48:
19:
12:
11:
5:
2216:
2214:
2206:
2205:
2200:
2190:
2189:
2184:
2183:
2176:
2169:
2161:
2158:
2157:
2136:
2124:
2123:
2093:
2058:
2015:
1980:
1952:(7): 3411–24.
1937:
1892:
1857:
1814:
1801:10.1038/ng1285
1779:
1734:
1691:
1638:
1609:
1580:
1547:
1504:
1468:
1466:
1463:
1460:
1459:
1400:
1386:
1345:
1304:
1286:
1268:
1247:
1225:
1224:
1222:
1219:
1175:
1174:
1171:
1170:
1165:
1155:
1154:
1148:
1147:
1144:
1143:
1141:
1139:
1132:
1131:
1124:
1117:
1113:
1112:
1109:
1108:
1098:
1097:
1091:
1088:
1087:
1065:
1064:
1058:
1054:
1053:
1050:
1049:
1039:
1038:
1032:
1029:
1028:
1002:
1001:
995:
991:
990:
987:
986:
978:
977:
971:
968:
967:
959:
958:
952:
946:
945:
942:
941:
933:
932:
926:
923:
922:
914:
913:
907:
901:
900:
897:
896:
888:
887:
881:
878:
877:
869:
868:
862:
856:
855:
850:
845:
841:
840:
830:
829:
826:
825:
814:
813:
811:
810:
805:
800:
795:
790:
785:
780:
775:
770:
765:
760:
754:
752:
748:
747:
745:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
674:
669:
664:
659:
654:
649:
647:focal adhesion
644:
639:
634:
629:
624:
618:
616:
612:
611:
609:
608:
603:
598:
592:
590:
586:
585:
575:
574:
571:
570:
567:
566:
558:
557:
546:
540:
539:
536:
535:
527:
526:
523:
522:
520:
519:
515:
511:
510:left lung lobe
507:
503:
499:
495:
491:
487:
483:
479:
476:
475:
464:
461:
460:
458:
457:
453:
449:
445:
441:
437:
433:
429:
425:
421:
417:
414:
413:
401:
400:
392:
381:
375:
374:
371:RNA expression
363:
362:
359:
358:
350:
346:
345:
337:
334:
329:
323:
322:
313:
306:
300:
296:
295:
290:
284:
283:
275:
274:
262:
261:
258:
257:
249:
245:
244:
236:
233:
228:
222:
221:
212:
205:
199:
195:
194:
187:
181:
180:
172:
171:
159:
158:
115:
111:
110:
102:
94:
93:
89:
88:
85:
84:
81:
80:
66:
65:
57:
56:
45:
39:
38:
30:
29:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
2215:
2204:
2201:
2199:
2196:
2195:
2193:
2182:
2177:
2175:
2170:
2168:
2163:
2162:
2156:
2154:
2150:
2146:
2145:chromosome 14
2142:
2137:
2134:
2130:
2120:
2116:
2112:
2108:
2104:
2100:
2099:Exp. Cell Res
2094:
2090:
2086:
2081:
2076:
2073:(3): 635–48.
2072:
2068:
2064:
2059:
2055:
2051:
2046:
2041:
2037:
2033:
2029:
2025:
2021:
2016:
2012:
2008:
2003:
1998:
1994:
1990:
1986:
1981:
1977:
1973:
1968:
1963:
1959:
1955:
1951:
1947:
1943:
1938:
1934:
1930:
1926:
1922:
1918:
1914:
1910:
1906:
1902:
1898:
1893:
1889:
1885:
1880:
1875:
1871:
1867:
1863:
1858:
1854:
1850:
1845:
1840:
1836:
1832:
1828:
1824:
1820:
1815:
1811:
1807:
1802:
1797:
1793:
1789:
1785:
1780:
1776:
1772:
1768:
1764:
1760:
1756:
1752:
1748:
1744:
1740:
1735:
1731:
1727:
1722:
1717:
1713:
1709:
1705:
1701:
1697:
1692:
1688:
1684:
1679:
1674:
1669:
1664:
1660:
1656:
1652:
1648:
1644:
1639:
1635:
1631:
1627:
1623:
1620:(5): 473–81.
1619:
1615:
1610:
1606:
1602:
1598:
1594:
1590:
1586:
1581:
1577:
1573:
1569:
1565:
1561:
1557:
1553:
1548:
1544:
1540:
1535:
1530:
1526:
1522:
1519:(3): 422–35.
1518:
1514:
1510:
1505:
1501:
1497:
1492:
1487:
1484:(3): 99–106.
1483:
1479:
1475:
1470:
1469:
1464:
1455:
1451:
1446:
1441:
1436:
1431:
1427:
1423:
1420:(7): e40098.
1419:
1415:
1411:
1404:
1401:
1396:
1390:
1387:
1382:
1378:
1373:
1368:
1364:
1360:
1356:
1349:
1346:
1341:
1337:
1332:
1327:
1323:
1319:
1315:
1308:
1305:
1300:
1296:
1290:
1287:
1282:
1278:
1272:
1269:
1265:
1261:
1256:
1254:
1252:
1248:
1244:
1240:
1235:
1233:
1231:
1227:
1220:
1218:
1216:
1210:
1208:
1204:
1200:
1196:
1192:
1189:
1185:
1181:
1169:
1164:
1160:
1156:
1153:
1149:
1142:
1140:
1137:
1133:
1129:
1125:
1122:
1118:
1114:
1107:
1105:
1099:
1095:
1092:
1086:
1084:
1080:
1076:
1072:
1066:
1062:
1059:
1055:
1048:
1046:
1040:
1036:
1033:
1027:
1025:
1021:
1017:
1013:
1009:
1003:
999:
996:
994:RefSeq (mRNA)
992:
985:
984:
979:
975:
972:
966:
965:
960:
956:
953:
951:
947:
940:
939:
934:
930:
927:
921:
920:
915:
911:
908:
906:
902:
895:
894:
889:
885:
882:
876:
875:
870:
866:
863:
861:
857:
854:
851:
849:
846:
842:
839:
835:
831:
824:
820:
815:
809:
806:
804:
801:
799:
796:
794:
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
755:
753:
750:
749:
743:
740:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
707:nuclear lumen
705:
703:
700:
698:
695:
693:
692:mitochondrion
690:
688:
685:
683:
680:
678:
675:
673:
672:cell junction
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
623:
620:
619:
617:
614:
613:
607:
606:actin binding
604:
602:
599:
597:
594:
593:
591:
588:
587:
584:
583:Gene ontology
580:
576:
564:
559:
555:
550:
547:
545:
541:
533:
528:
517:
513:
509:
505:
501:
497:
493:
489:
485:
481:
480:
477:
473:
468:
465:
455:
451:
447:
443:
440:renal medulla
439:
435:
431:
427:
423:
419:
418:
415:
411:
406:
403:
402:
399:
397:
393:
391:
390:
386:
385:
382:
380:
376:
372:
368:
364:
356:
351:
347:
343:
338:
328:
324:
317:
310:
304:
297:
289:
285:
281:
276:
272:
267:
263:
255:
250:
246:
242:
237:
227:
223:
216:
209:
203:
196:
192:
186:
182:
178:
173:
169:
164:
160:
156:
152:
148:
144:
140:
136:
132:
128:
124:
120:
112:
107:
100:
95:
90:
79:
77:
73:
67:
62:
59:
58:
54:
51:
44:
40:
35:
31:
27:
22:
16:
2153:expanding it
2138:
2102:
2098:
2070:
2066:
2030:(1): 55–65.
2027:
2023:
1992:
1988:
1949:
1945:
1900:
1896:
1869:
1865:
1826:
1822:
1791:
1787:
1742:
1738:
1703:
1699:
1650:
1646:
1617:
1613:
1588:
1584:
1559:
1555:
1516:
1512:
1481:
1477:
1417:
1413:
1403:
1389:
1362:
1358:
1348:
1324:(1): 63–70.
1321:
1317:
1307:
1298:
1289:
1280:
1271:
1211:
1207:cytoskeleton
1187:
1179:
1178:
1104:NP_001005510
1101:
1068:
1045:NM_001005510
1042:
1005:
981:
962:
936:
917:
891:
872:
852:
847:
727:cytoskeleton
502:right kidney
394:
387:
114:External IDs
69:
15:
1989:J. Cell Sci
1866:J. Cell Sci
1794:(1): 40–5.
1585:J. Cell Sci
1556:J. Cell Sci
1359:J Biol Chem
662:nucleoplasm
448:sural nerve
353:76,157,700
340:75,864,908
252:64,226,433
239:63,761,899
92:Identifiers
2192:Categories
2024:Genome Res
1823:Genome Res
1788:Nat. Genet
1513:Genome Res
1266:, May 2017
1245:, May 2017
1221:References
742:centrosome
682:Z discdkac
456:left ovary
398:(ortholog)
135:HomoloGene
2143:on human
1180:Nesprin-2
1083:NP_878918
1079:NP_878917
1075:NP_878914
1071:NP_055995
1024:NM_182914
1020:NM_182913
1016:NM_182912
1012:NM_182910
1008:NM_015180
838:Orthologs
677:myofibril
667:aggresome
622:cytoplasm
143:GeneCards
2119:17462627
2089:17081983
2054:16344560
2011:16079285
1976:15843432
1933:13047538
1925:15790807
1888:15671068
1853:15489334
1810:14702039
1775:23832536
1767:12958361
1730:12508121
1687:12477932
1634:12408964
1614:Genomics
1605:12118075
1576:11792814
1543:11230166
1500:12168954
1454:22768332
1414:PLOS ONE
1381:10878022
1340:10231032
1262:–
1241:–
1152:Wikidata
817:Sources:
642:membrane
2045:1356129
1967:1165422
1905:Bibcode
1897:Science
1747:Bibcode
1739:Science
1708:Bibcode
1655:Bibcode
1478:DNA Res
1445:3388047
1422:Bibcode
1318:DNA Res
1264:Ensembl
1243:Ensembl
1215:enaptin
1203:F-actin
1199:nesprin
1184:protein
950:UniProt
905:Ensembl
844:Species
823:QuickGO
732:nucleus
373:pattern
231:14q23.2
131:2449316
99:Aliases
2117:
2087:
2052:
2042:
2009:
1974:
1964:
1931:
1923:
1886:
1851:
1844:528928
1841:
1808:
1773:
1765:
1728:
1700:Nature
1685:
1678:139241
1675:
1632:
1603:
1574:
1541:
1534:311072
1531:
1498:
1452:
1442:
1379:
1338:
1138:search
1136:PubMed
983:Q6ZWQ0
964:Q8WXH0
893:319565
860:Entrez
544:BioGPS
486:zygote
123:608442
2147:is a
1929:S2CID
1771:S2CID
1195:exons
1188:SYNE2
1182:is a
874:23224
853:Mouse
848:Human
819:Amigo
396:Mouse
389:Human
336:Start
271:Mouse
235:Start
168:Human
147:SYNE2
139:56700
106:SYNE2
24:SYNE2
2149:stub
2141:gene
2115:PMID
2085:PMID
2067:Cell
2050:PMID
2007:PMID
1972:PMID
1921:PMID
1884:PMID
1849:PMID
1806:PMID
1763:PMID
1726:PMID
1683:PMID
1630:PMID
1601:PMID
1572:PMID
1539:PMID
1496:PMID
1450:PMID
1377:PMID
1336:PMID
1191:gene
379:Bgee
327:Band
288:Chr.
226:Band
185:Chr.
119:OMIM
76:4FI9
72:4DXS
53:RCSB
50:PDBe
2107:doi
2103:313
2075:doi
2071:127
2040:PMC
2032:doi
1997:doi
1993:118
1962:PMC
1954:doi
1913:doi
1901:308
1874:doi
1870:118
1839:PMC
1831:doi
1796:doi
1755:doi
1743:301
1716:doi
1704:421
1673:PMC
1663:doi
1622:doi
1593:doi
1589:115
1564:doi
1560:114
1529:PMC
1521:doi
1486:doi
1440:PMC
1430:doi
1367:doi
1363:275
1326:doi
518:lip
349:End
248:End
151:OMA
127:MGI
43:PDB
2194::
2113:.
2101:.
2083:.
2069:.
2065:.
2048:.
2038:.
2028:16
2026:.
2022:.
2005:.
1991:.
1987:.
1970:.
1960:.
1950:16
1948:.
1944:.
1927:.
1919:.
1911:.
1899:.
1882:.
1868:.
1864:.
1847:.
1837:.
1827:14
1825:.
1821:.
1804:.
1792:36
1790:.
1786:.
1769:.
1761:.
1753:.
1741:.
1724:.
1714:.
1702:.
1698:.
1681:.
1671:.
1661:.
1651:99
1649:.
1645:.
1628:.
1618:80
1616:.
1599:.
1587:.
1570:.
1558:.
1554:.
1537:.
1527:.
1517:11
1515:.
1511:.
1494:.
1480:.
1476:.
1448:.
1438:.
1428:.
1416:.
1412:.
1375:.
1361:.
1357:.
1334:.
1320:.
1316:.
1297:.
1279:.
1250:^
1229:^
821:/
355:bp
342:bp
254:bp
241:bp
149:;
145::
141:;
137::
133:;
129::
125:;
121::
74:,
2180:e
2173:t
2166:v
2155:.
2121:.
2109::
2091:.
2077::
2056:.
2034::
2013:.
1999::
1978:.
1956::
1935:.
1915::
1907::
1890:.
1876::
1855:.
1833::
1812:.
1798::
1777:.
1757::
1749::
1732:.
1718::
1710::
1689:.
1665::
1657::
1636:.
1624::
1607:.
1595::
1578:.
1566::
1545:.
1523::
1502:.
1488::
1482:9
1456:.
1432::
1424::
1418:7
1397:.
1383:.
1369::
1342:.
1328::
1322:6
1301:.
1283:.
273:)
170:)
153::
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