Knowledge (XXG)

SYNGR1

Source 📝

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Kedra D, Pan HQ, Seroussi E, Fransson I, Guilbaud C, Collins JE, Dunham I, Blennow E, Roe BA, Piehl F, Dumanski JP (Oct 1998). "Characterization of the human synaptogyrin gene family".
255: 154: 750: 731: 77: 1751: 1568:"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" 1722: 1741: 1638:
Chi A, Valencia JC, Hu ZZ, et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes".
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Verma R, Chauhan C, Saleem Q, et al. (2004). "A nonsense mutation in the synaptogyrin 1 gene in a family with schizophrenia".
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without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively
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Cheng MC, Chen CH (2007). "Identification of rare mutations of synaptogyrin 1 gene in patients with schizophrenia".
1715: 1320:"Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex" 247: 146: 795: 65: 1490:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" 776: 1708: 129: 1366: 1288: 44: 1067: 1431: 1194: 89: 1355:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 957: 953: 932: 928: 924: 898: 894: 873: 869: 865: 506: 1655: 1626: 1597: 1554: 1519: 1476: 1423: 1394: 1341: 1306: 1235: 1186: 1055: 37: 1692: 1647: 1618: 1587: 1579: 1544: 1509: 1501: 1466: 1456: 1415: 1384: 1374: 1331: 1296: 1225: 1178: 1051: 499: 492: 334: 265: 209: 164: 85: 309: 1370: 1292: 1592: 1567: 1071: 1514: 1489: 1471: 1444: 1389: 1354: 1336: 1319: 1230: 1213: 665: 660: 655: 650: 645: 640: 635: 619: 614: 609: 604: 599: 594: 589: 584: 579: 574: 569: 564: 548: 1735: 1688: 1622: 535: 1435: 69: 1419: 1198: 327: 106: 93: 1533:"SYNGR1 is associated with schizophrenia and bipolar disorder in southern India" 1156:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1214:"Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I" 1062:
cells. The exact function of this protein is unclear, but studies of a similar
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Janz R, Sudhof TC, Hammer RE, Unni V, Siegelbaum SA, Bolshakov VY (Jan 2000).
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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Mirnics K, Middleton FA, Marquez A, et al. (2000).
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encoding three different isoforms have been identified.
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Gerhard DS, Wagner L, Feingold EA, et al. (2004).
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Collins JE, Wright CL, Edwards CA, et al. (2005).
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Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
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regulation of short-term neuronal synaptic plasticity
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regulation of long-term neuronal synaptic plasticity
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dentate gyrus of hippocampal formation granule cell
1531:Verma R, Kubendran S, Das SK, et al. (2006). 1112: 1110: 1108: 1091: 1089: 1087: 1275:Dunham I, Shimizu N, Roe BA, et al. (1999). 264: 163: 656:cellular response to leukemia inhibitory factor 620:integral component of synaptic vesicle membrane 16:Protein-coding gene in the species Homo sapiens 1117:GRCm38: Ensembl release 89: ENSMUSG00000022415 1716: 8: 1096:GRCh38: Ensembl release 89: ENSG00000100321 1723: 1709: 691: 531: 305: 204: 101: 1591: 1548: 1513: 1470: 1460: 1388: 1378: 1335: 1300: 1277:"The DNA sequence of human chromosome 22" 1229: 1251: 1249: 1083: 666:synaptic vesicle membrane organization 18: 1066:protein suggest that it functions in 269: 230: 225: 168: 127: 122: 7: 1673: 1671: 1257:"Entrez Gene: SYNGR1 synaptogyrin 1" 1695:. You can help Knowledge (XXG) by 943: 914: 884: 855: 831: 812: 786: 767: 741: 722: 487: 405: 343: 322: 14: 1040:that in humans is encoded by the 379:lateral nuclear group of thalamus 1675: 1623:10.1016/j.jpsychires.2006.08.010 505: 498: 491: 253: 246: 240: 217: 152: 145: 139: 114: 1611:Journal of Psychiatric Research 1752:Human chromosome 22 gene stubs 1420:10.1016/j.biopsych.2003.10.012 1050:This gene encodes an integral 570:integral component of membrane 516:More reference expression data 471:More reference expression data 363:right hemisphere of cerebellum 1: 1337:10.1016/S0896-6273(00)00085-4 1231:10.1016/S0896-6273(00)81122-8 238: 137: 1742:Genes on human chromosome 22 1359:Proc. Natl. Acad. Sci. U.S.A 1747:Biology of bipolar disorder 367:paraflocculus of cerebellum 1768: 1670: 610:azurophil granule membrane 1550:10.1007/s10038-005-0307-z 1152:"Mouse PubMed Reference:" 1134:"Human PubMed Reference:" 1020: 1015: 1011: 1004: 988: 969: 950: 921: 910: 891: 862: 851: 838: 834: 819: 815: 806: 793: 789: 774: 770: 761: 748: 744: 729: 725: 716: 701: 694: 690: 674: 590:synaptic vesicle membrane 534: 530: 513: 490: 481: 468: 453:medial geniculate nucleus 449:medial vestibular nucleus 417: 408: 391:anterior cingulate cortex 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 1462:10.1186/gb-2004-5-10-r84 975:Chr 22: 39.35 – 39.39 Mb 651:neutrophil degranulation 445:dorsal tegmental nucleus 1380:10.1073/pnas.242603899 580:neuromuscular junction 425:superior frontal gyrus 1183:10.1007/s004390050795 982:Chr 15: 79.98 – 80 Mb 441:medial dorsal nucleus 232:Chromosome 15 (mouse) 130:Chromosome 22 (human) 661:regulated exocytosis 1371:2002PNAS...9916899M 1293:1999Natur.402..489D 1068:synaptic plasticity 1054:associated with pre 615:cytoplasmic vesicle 1683:This article on a 1584:10.1101/gr.4039406 1506:10.1101/gr.2596504 796:ENSMUSG00000022415 629:Biological process 558:Cellular component 542:Molecular function 375:right frontal lobe 94:SYNGR1 - orthologs 1704: 1703: 1652:10.1021/pr060363j 1365:(26): 16899–903. 1056:synaptic vesicles 1031: 1030: 1027: 1026: 1000: 999: 965: 964: 940: 939: 906: 905: 881: 880: 847: 846: 828: 827: 802: 801: 783: 782: 757: 756: 738: 737: 686: 685: 641:protein targeting 526: 525: 522: 521: 477: 476: 464: 463: 457:cerebellar vermis 433:prefrontal cortex 429:cerebellar cortex 402: 401: 383:cerebellar vermis 300: 299: 199: 198: 1759: 1725: 1718: 1711: 1679: 1672: 1663: 1634: 1605: 1595: 1562: 1552: 1527: 1517: 1484: 1474: 1464: 1439: 1408:Biol. Psychiatry 1402: 1392: 1382: 1349: 1339: 1314: 1304: 1287:(6761): 489–95. 1261: 1260: 1253: 1244: 1243: 1233: 1209: 1203: 1202: 1166: 1160: 1159: 1148: 1142: 1141: 1130: 1124: 1114: 1103: 1093: 1072:spliced variants 1052:membrane protein 1013: 1012: 984: 977: 960: 944: 935: 915: 911:RefSeq (protein) 901: 885: 876: 856: 832: 813: 787: 768: 742: 723: 692: 600:synaptic vesicle 532: 518: 509: 502: 495: 488: 473: 413: 411:Top expressed in 406: 359:Brodmann area 10 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 48:, synaptogyrin 1 47: 40: 19: 1767: 1766: 1762: 1761: 1760: 1758: 1757: 1756: 1732: 1731: 1730: 1729: 1668: 1666: 1646:(11): 3135–44. 1640:J. Proteome Res 1637: 1617:(12): 1027–31. 1608: 1565: 1530: 1500:(10B): 2121–7. 1487: 1442: 1405: 1352: 1317: 1274: 1270: 1268:Further reading 1265: 1264: 1255: 1254: 1247: 1211: 1210: 1206: 1168: 1167: 1163: 1150: 1149: 1145: 1132: 1131: 1127: 1115: 1106: 1094: 1085: 1080: 1022:View/Edit Mouse 1017:View/Edit Human 980: 973: 970:Location (UCSC) 956: 952: 931: 927: 923: 897: 893: 872: 868: 864: 777:ENSG00000100321 670: 624: 605:plasma membrane 553: 549:protein binding 514: 504: 503: 497: 496: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 395:Brodmann area 9 393: 389: 387:cingulate gyrus 385: 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1765: 1763: 1755: 1754: 1749: 1744: 1734: 1733: 1728: 1727: 1720: 1713: 1705: 1702: 1701: 1680: 1665: 1664: 1635: 1606: 1563: 1543:(12): 635–40. 1528: 1485: 1440: 1403: 1350: 1315: 1302:10.1038/990031 1271: 1269: 1266: 1263: 1262: 1245: 1224:(3): 687–700. 1204: 1161: 1143: 1125: 1104: 1082: 1081: 1079: 1076: 1034:Synaptogyrin-1 1029: 1028: 1025: 1024: 1019: 1009: 1008: 1002: 1001: 998: 997: 995: 993: 986: 985: 978: 971: 967: 966: 963: 962: 948: 947: 941: 938: 937: 919: 918: 912: 908: 907: 904: 903: 889: 888: 882: 879: 878: 860: 859: 853: 849: 848: 845: 844: 836: 835: 829: 826: 825: 817: 816: 810: 804: 803: 800: 799: 791: 790: 784: 781: 780: 772: 771: 765: 759: 758: 755: 754: 746: 745: 739: 736: 735: 727: 726: 720: 714: 713: 708: 703: 699: 698: 688: 687: 684: 683: 672: 671: 669: 668: 663: 658: 653: 648: 643: 638: 632: 630: 626: 625: 623: 622: 617: 612: 607: 602: 597: 592: 587: 582: 577: 572: 567: 561: 559: 555: 554: 552: 551: 545: 543: 539: 538: 528: 527: 524: 523: 520: 519: 511: 510: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1764: 1753: 1750: 1748: 1745: 1743: 1740: 1739: 1737: 1726: 1721: 1719: 1714: 1712: 1707: 1706: 1700: 1698: 1694: 1690: 1689:chromosome 22 1686: 1681: 1678: 1674: 1669: 1661: 1657: 1653: 1649: 1645: 1641: 1636: 1632: 1628: 1624: 1620: 1616: 1612: 1607: 1603: 1599: 1594: 1589: 1585: 1581: 1577: 1573: 1569: 1564: 1560: 1556: 1551: 1546: 1542: 1538: 1537:J. Hum. Genet 1534: 1529: 1525: 1521: 1516: 1511: 1507: 1503: 1499: 1495: 1491: 1486: 1482: 1478: 1473: 1468: 1463: 1458: 1454: 1450: 1446: 1441: 1437: 1433: 1429: 1425: 1421: 1417: 1413: 1409: 1404: 1400: 1396: 1391: 1386: 1381: 1376: 1372: 1368: 1364: 1360: 1356: 1351: 1347: 1343: 1338: 1333: 1329: 1325: 1321: 1316: 1312: 1308: 1303: 1298: 1294: 1290: 1286: 1282: 1278: 1273: 1272: 1267: 1258: 1252: 1250: 1246: 1241: 1237: 1232: 1227: 1223: 1219: 1215: 1208: 1205: 1200: 1196: 1192: 1188: 1184: 1180: 1177:(2): 131–41. 1176: 1172: 1165: 1162: 1157: 1153: 1147: 1144: 1139: 1135: 1129: 1126: 1122: 1118: 1113: 1111: 1109: 1105: 1101: 1097: 1092: 1090: 1088: 1084: 1077: 1075: 1073: 1069: 1065: 1061: 1057: 1053: 1048: 1046: 1043: 1039: 1035: 1023: 1018: 1014: 1010: 1007: 1003: 996: 994: 991: 987: 983: 979: 976: 972: 968: 961: 959: 955: 949: 945: 942: 936: 934: 930: 926: 920: 916: 913: 909: 902: 900: 896: 890: 886: 883: 877: 875: 871: 867: 861: 857: 854: 852:RefSeq (mRNA) 850: 843: 842: 837: 833: 830: 824: 823: 818: 814: 811: 809: 805: 798: 797: 792: 788: 785: 779: 778: 773: 769: 766: 764: 760: 753: 752: 747: 743: 740: 734: 733: 728: 724: 721: 719: 715: 712: 709: 707: 704: 700: 697: 693: 689: 682: 678: 673: 667: 664: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 633: 631: 628: 627: 621: 618: 616: 613: 611: 608: 606: 603: 601: 598: 596: 593: 591: 588: 586: 583: 581: 578: 576: 575:cell junction 573: 571: 568: 566: 563: 562: 560: 557: 556: 550: 547: 546: 544: 541: 540: 537: 536:Gene ontology 533: 529: 517: 512: 508: 501: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 271:15|15 E1 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 1697:expanding it 1682: 1667: 1643: 1639: 1614: 1610: 1578:(1): 55–65. 1575: 1571: 1540: 1536: 1497: 1493: 1452: 1448: 1414:(2): 196–9. 1411: 1407: 1362: 1358: 1330:(1): 53–67. 1327: 1323: 1284: 1280: 1221: 1217: 1207: 1174: 1170: 1164: 1155: 1146: 1137: 1128: 1049: 1041: 1033: 1032: 951: 922: 892: 863: 839: 820: 794: 775: 749: 730: 710: 705: 371:frontal pole 333: 326: 53:External IDs 1455:(10): R84. 1449:Genome Biol 292:80,003,702 279:79,975,535 191:39,385,575 178:39,349,925 31:Identifiers 1736:Categories 1572:Genome Res 1494:Genome Res 1123:, May 2017 1102:, May 2017 1078:References 565:melanosome 337:(ortholog) 74:HomoloGene 1687:on human 1171:Hum Genet 958:NP_997591 954:NP_033329 933:NP_663791 929:NP_663783 925:NP_004702 899:NM_207708 895:NM_009303 874:NM_145731 870:NM_004711 866:NM_145738 696:Orthologs 437:subiculum 82:GeneCards 1660:17081065 1631:17049558 1602:16344560 1559:16215643 1524:15489334 1481:15461802 1436:26812099 1428:14732601 1399:12477932 1346:11086983 1311:10591208 1240:10595519 1119:– 1098:– 1060:neuronal 1006:Wikidata 675:Sources: 595:membrane 1593:1356129 1367:Bibcode 1289:Bibcode 1199:2310048 1191:9760194 1121:Ensembl 1100:Ensembl 1038:protein 808:UniProt 763:Ensembl 702:Species 681:QuickGO 585:synapse 312:pattern 170:22q13.1 70:1328323 38:Aliases 1658:  1629:  1600:  1590:  1557:  1522:  1515:528928 1512:  1479:  1472:545604 1469:  1434:  1426:  1397:  1390:139241 1387:  1344:  1324:Neuron 1309:  1281:Nature 1238:  1218:Neuron 1197:  1189:  1064:murine 1042:SYNGR1 992:search 990:PubMed 841:O55100 822:O43759 718:Entrez 483:BioGPS 86:SYNGR1 62:603925 45:SYNGR1 22:SYNGR1 1691:is a 1432:S2CID 1195:S2CID 1036:is a 751:20972 711:Mouse 706:Human 677:Amigo 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 1693:stub 1685:gene 1656:PMID 1627:PMID 1598:PMID 1555:PMID 1520:PMID 1477:PMID 1424:PMID 1395:PMID 1342:PMID 1307:PMID 1236:PMID 1187:PMID 1045:gene 732:9145 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 78:3456 58:OMIM 1648:doi 1619:doi 1588:PMC 1580:doi 1545:doi 1510:PMC 1502:doi 1467:PMC 1457:doi 1416:doi 1385:PMC 1375:doi 1332:doi 1297:doi 1285:402 1226:doi 1179:doi 1175:103 1058:in 288:End 187:End 90:OMA 66:MGI 1738:: 1654:. 1642:. 1625:. 1615:41 1613:. 1596:. 1586:. 1576:16 1574:. 1570:. 1553:. 1541:50 1539:. 1535:. 1518:. 1508:. 1498:14 1496:. 1492:. 1475:. 1465:. 1451:. 1447:. 1430:. 1422:. 1412:55 1410:. 1393:. 1383:. 1373:. 1363:99 1361:. 1357:. 1340:. 1328:28 1326:. 1322:. 1305:. 1295:. 1283:. 1279:. 1248:^ 1234:. 1222:24 1220:. 1216:. 1193:. 1185:. 1173:. 1154:. 1136:. 1107:^ 1086:^ 1047:. 679:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 1724:e 1717:t 1710:v 1699:. 1662:. 1650:: 1644:5 1633:. 1621:: 1604:. 1582:: 1561:. 1547:: 1526:. 1504:: 1483:. 1459:: 1453:5 1438:. 1418:: 1401:. 1377:: 1369:: 1348:. 1334:: 1313:. 1299:: 1291:: 1259:. 1242:. 1228:: 1201:. 1181:: 1158:. 1140:. 212:) 109:) 92::

Index

Aliases
SYNGR1
OMIM
603925
MGI
1328323
HomoloGene
3456
GeneCards
SYNGR1
OMA
SYNGR1 - orthologs
Human
Chromosome 22 (human)
Chr.
Chromosome 22 (human)
Chromosome 22 (human)
Genomic location for SYNGR1
Genomic location for SYNGR1
Band
bp
bp
Mouse
Chromosome 15 (mouse)
Chr.
Chromosome 15 (mouse)
Genomic location for SYNGR1
Genomic location for SYNGR1
Band
bp

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