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Sabeeha Merchant

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to remove surface metal ions. Her early work considered signalling that responded to copper, but she has since expanded into iron sensing and the impact of iron deficiencies on photosynthesis. In an effort to understand copper sensing, she studied mutants that did not produce plastocyanin. She
192:. She was unsure what to specialise in, and took an aptitude test at the age of 12. Merchant scored well in the science and the humanities, but was selected for the sciences as there were not enough girls in the class. Merchant attended the 323:(UCLA). She works on metal nutrient deficiency, which requires water purification systems to generate water that is free of metal contaminants. In her lab experiments are performed in rigorously cleaned glassware, using 960:
Redinbo, Matthew R.; Cascio, Duilio; Choukair, Marie K.; Rice, Danny; Merchant, Sabeeha; Yeates, Todd O. (1993-10-12). "The 1.5-.ANG. crystal structure of plastocyanin from the green alga Chlamydomonas reinhardtii".
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regulation was CRR1 (Copper Response Regulator). She worked with Todd Yeates on the structure and genetics of plastocyanin and cytochrome c, uncovering the crystal structures of both proteins. She was awarded the
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Kerfeld, Cheryl A.; Anwar, Haroon P.; Interrante, Robert; Merchant, Sabeeha; Yeates, Todd O. (1995). "The Structure of Chloroplast Cytochromec6at 1.9 Ă… Resolution: Evidence for Functional Oligomerization".
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Grossman, Arthur R.; Rokhsar, Daniel S.; Grigoriev, Igor V.; Zhou, Kemin; Werner, Gregory; Szajkowski, Lukasz; Porter, Aaron; Poliakov, Alexander; Otillar, Bobby (2007-10-12).
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in 2018. At Berkeley, she is a Professor of Plant and Microbial Biology. Her lab continue to investigate the metabolism of iron and copper, as well as
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fellowship there was a fire in the laboratory. During this time she began to read in the library, investigating role of metals in the regulation of
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to show that whilst plastocyanin is continuously translated, it becomes degraded in systems without enough copper. Merchant showed that the RNA of
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in 1978 and became interested in the chemistry of living cells whilst working under the supervision of Glenn Chambliss. Merchant majored in
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The Chlamydomonas reinhardi chloroplast coupling factor 1 : its purification, properties, and aspects of its synthesis in vivo
1618: 193: 1633: 197: 1551: 744: 489: 394: 1658: 477: 467: 334: 177: 1211: 694: 1623: 447: 405: 337: 71: 311: 291: 228: 222: 269: 1576:"Sabeeha Merchant elected to German National Academy of Sciences Leopoldina | UCLA Chemistry and Biochemistry" 1007: 1643: 1383: 245: 1479: 216:'s secretary, but he encouraged her to apply for graduate programs. She eventually earned her PhD at the 538: 265: 804:"Regulation by copper of the expression of plastocyanin and cytochrome c552 in Chlamydomonas reinhardi" 1638: 1109: 1044: 588: 374: 299: 1527: 261: 1552:"Sabeeha Merchant receives 2012 Darbaker Prize in Phycology | UCLA Chemistry and Biochemistry" 1455: 1340: 1322: 1239: 1145: 1127: 1078: 1060: 986: 978: 942: 934: 898: 880: 841: 823: 784: 624: 606: 519: 324: 307: 264:. She started working on light-regulated gene expression. Unfortunately, four months into her 209: 719: 516:
Molecular Biology of Chlamydomonas: Chloroplasts and Mitochondria. Advances in Photosynthesis
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and earned her bachelor's degree in 1979. She joined the Enzyme Institute to work as
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also contained cytochrome c6, which could step in during photosynthesis if needed.
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in 1983. She worked alongside Bruce Selman on the single-cell alga
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in the absence of light. During her doctorate Merchant purified
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is a model organism as it can build the relevant systems for
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in 2014. She also served on the Life Sciences jury for the
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from 2015-2019. She serves on the Board of Directors of
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coupling factor 1, a component of the pathway that uses
196:. At the age of fifteen, Merchant started university at 745:"Lawrence Bogorad 1921 - 2003: A Biographical Memoir" 436:
American Association for the Advancement of Science
328:discovered that the regulator for plastocyanin and 126: 104: 90: 67: 56: 28: 21: 720:"Merchant publications from Ph.D. thesis research" 356:Max Planck Institute of Molecular Plant Physiology 1212:"Meet our new faculty: Sabeeha Merchant, biology" 695:"Meet our new faculty: Sabeeha Merchant, biology" 167:In 2010 Merchant led the team that sequenced the 163:. She studies the photosynthetic metabolism and 1102:Proceedings of the National Academy of Sciences 581:Proceedings of the National Academy of Sciences 354:in 2009. She spent 2012 on a sabbatical at the 350:genome. Her inaugural article was published in 298:is produced when copper is available. She used 285:Merchant was the first to demonstrate that the 1098:"His protects heme as it crosses the membrane" 1408:"California prof gets National Science Award" 278:. She studied how cells detect the levels of 8: 344:. In 2007 she led a team that sequenced the 306:, an iron-based protein, is only present in 1654:University of California, Berkeley faculty 643:"Indian-American scientist honoured by US" 256:After completing her PhD, Merchant joined 77:Member of the National Academy of Sciences 18: 1334: 1139: 1121: 1072: 892: 835: 618: 600: 340:for her contributions to the assembly of 507: 398:since 2005, and was editor-in-chief of 1649:University of Wisconsin–Madison alumni 1301:SalomĂ©, Patrice A. (18 October 2019). 649:. The Times of India. February 9, 2006 494:Recognized as a Pioneer Member of the 1234: 1232: 1002: 1000: 570: 568: 566: 484:American Academy of Arts and Sciences 429:University of California, Los Angeles 321:University of California, Los Angeles 99:University of California, Los Angeles 7: 665: 663: 564: 562: 560: 558: 556: 554: 552: 550: 548: 546: 496:American Society of Plant Biologists 454:American Society of Plant Biologists 442:American Society of Plant Biologists 422:American Society of Plant Biologists 1366:"Annual Reviews Board of Directors" 1281:10.1146/annurev.pp.55.042204.100001 1664:Annual Reviews (publisher) editors 877:10.1002/j.1460-2075.1987.tb02540.x 859:Merchant, S.; Bogorad, L. (1987). 781:10.1093/oxfordjournals.pcp.a075363 371:University of California, Berkeley 176:. She was elected a member of the 161:University of California, Berkeley 95:University of California, Berkeley 14: 1629:American people of Indian descent 1244:plantandmicrobiology.berkeley.edu 461:Alexander von Humboldt Foundation 270:photosynthetic electron transport 802:Merchant, S; Bogorad, L (1986). 575:Davis, Tinsley H. (2015-03-03). 194:J.B. Petit High School for Girls 1263:Delmer, Deborah (2 June 2004). 416:Her awards and honors include; 218:University of Wisconsin–Madison 206:University of Wisconsin–Madison 61:University of Wisconsin–Madison 1269:Annual Review of Plant Biology 808:Molecular and Cellular Biology 490:Academy of Sciences Leopoldina 395:Annual Review of Plant Biology 319:In 1987 Merchant moved to the 155:(born 1959) is a professor of 1: 577:"Profile of Sabeeha Merchant" 1480:"Charles F. Kettering Award" 1384:"Charles Albert Shull Award" 1008:"Gilbert Morgan Smith Medal" 919:Journal of Molecular Biology 478:Botanical Society of America 468:National Academy of Sciences 335:National Academy of Sciences 178:National Academy of Sciences 388:Merchant has served as the 1680: 514:Merchant, Sabeeha (1998). 456:Charles F. Kettering Award 448:Gilbert Morgan Smith Medal 424:Charles Albert Shull Award 338:Gilbert Morgan Smith Medal 282:and developed antibodies. 72:Gilbert Morgan Smith Medal 773:Plant and Cell Physiology 431:Herbert Newby McCoy Award 292:Chlamydomonas reinhardtii 229:Chlamydomonas reinhardtii 223:Chlamydomonas reinhardtii 153:Sabeeha Sabanali Merchant 122: 83: 33:Sabeeha Sabanali Merchant 1096:Merchant, S. S. (2009). 184:Early life and education 1619:Indian women scientists 1265:"Preface by the Editor" 1123:10.1073/pnas.0905189106 1057:10.1126/science.1143609 602:10.1073/pnas.1500798112 310:cells. She showed that 1634:Indian women academics 1600:"ASPB Pioneer Members" 1580:www.chemistry.ucla.edu 1556:www.chemistry.ucla.edu 931:10.1006/jmbi.1995.0404 369:Merchant moved to the 246:adenosine triphosphate 1508:www.mpimp-golm.mpg.de 1168:www.mpimp-golm.mpg.de 539:Europe PubMed Central 266:postdoctoral research 188:Merchant was born in 1319:10.1105/tpc.19.00817 488:2016 Elected to the 482:2014 Elected to the 466:2012 Elected to the 375:comparative genomics 300:pulse-chase analysis 198:St. Xavier's College 1659:Writers from Mumbai 1114:2009PNAS..10610069M 1108:(25): 10069–10070. 1049:2007Sci...318..245M 975:10.1021/bi00091a005 969:(40): 10560–10567. 820:10.1128/mcb.6.2.462 743:Merchant, Sabeeha. 593:2015PNAS..112.2633D 440:2008 Fellow of the 434:2005 Fellow of the 252:Research and career 1528:"Sabeeha Merchant" 1303:"Sabeeha Merchant" 537:publications from 262:Harvard University 1624:Indian biologists 1532:www.nasonline.org 1313:(12): 2814–2816. 1043:(5848): 245–250. 1012:www.nasonline.org 724:www.chem.ucla.edu 524:978-0-7923-5174-0 412:Awards and honors 325:hydrochloric acid 210:molecular biology 204:. She joined the 150: 149: 85:Scientific career 1671: 1604: 1603: 1596: 1590: 1589: 1587: 1586: 1572: 1566: 1565: 1563: 1562: 1548: 1542: 1541: 1539: 1538: 1524: 1518: 1517: 1515: 1514: 1500: 1494: 1493: 1491: 1490: 1476: 1470: 1469: 1467: 1466: 1456:"Fellow of ASPB" 1452: 1446: 1445: 1443: 1442: 1428: 1422: 1421: 1419: 1418: 1404: 1398: 1397: 1395: 1394: 1380: 1374: 1373: 1362: 1356: 1355: 1353: 1351: 1338: 1298: 1292: 1291: 1289: 1287: 1260: 1254: 1253: 1251: 1250: 1236: 1227: 1226: 1224: 1223: 1208: 1202: 1201: 1199: 1198: 1184: 1178: 1177: 1175: 1174: 1160: 1154: 1153: 1143: 1125: 1093: 1087: 1086: 1076: 1028: 1022: 1021: 1019: 1018: 1004: 995: 994: 957: 951: 950: 913: 907: 906: 896: 871:(9): 2531–2535. 865:The EMBO Journal 856: 850: 849: 839: 799: 793: 792: 768: 762: 761: 759: 758: 749: 740: 734: 733: 731: 730: 716: 710: 709: 707: 706: 691: 685: 684: 682: 681: 667: 658: 657: 655: 654: 639: 633: 632: 622: 604: 587:(9): 2633–2634. 572: 541: 535:Sabeeha Merchant 532: 526: 512: 308:copper deficient 258:Lawrence Bogorad 146: 143: 141: 139: 137: 135: 133: 118: 46: 42: 40: 23:Sabeeha Merchant 19: 1679: 1678: 1674: 1673: 1672: 1670: 1669: 1668: 1609: 1608: 1607: 1598: 1597: 1593: 1584: 1582: 1574: 1573: 1569: 1560: 1558: 1550: 1549: 1545: 1536: 1534: 1526: 1525: 1521: 1512: 1510: 1502: 1501: 1497: 1488: 1486: 1478: 1477: 1473: 1464: 1462: 1454: 1453: 1449: 1440: 1438: 1430: 1429: 1425: 1416: 1414: 1406: 1405: 1401: 1392: 1390: 1382: 1381: 1377: 1364: 1363: 1359: 1349: 1347: 1300: 1299: 1295: 1285: 1283: 1262: 1261: 1257: 1248: 1246: 1238: 1237: 1230: 1221: 1219: 1210: 1209: 1205: 1196: 1194: 1186: 1185: 1181: 1172: 1170: 1162: 1161: 1157: 1095: 1094: 1090: 1030: 1029: 1025: 1016: 1014: 1006: 1005: 998: 959: 958: 954: 915: 914: 910: 858: 857: 853: 801: 800: 796: 770: 769: 765: 756: 754: 747: 742: 741: 737: 728: 726: 718: 717: 713: 704: 702: 693: 692: 688: 679: 677: 675:www.chem.uzh.ch 669: 668: 661: 652: 650: 641: 640: 636: 574: 573: 544: 533: 529: 513: 509: 505: 414: 390:editor-in-chief 254: 186: 130: 116: 97: 75: 57:Alma mater 52: 47: 44: 43:August 31, 1959 38: 36: 35: 34: 24: 17: 16:Plant scientist 12: 11: 5: 1677: 1675: 1667: 1666: 1661: 1656: 1651: 1646: 1641: 1636: 1631: 1626: 1621: 1611: 1610: 1606: 1605: 1591: 1567: 1543: 1519: 1495: 1471: 1447: 1423: 1399: 1375: 1370:Annual Reviews 1357: 1307:The Plant Cell 1293: 1255: 1228: 1203: 1179: 1155: 1088: 1023: 996: 952: 925:(5): 627–647. 908: 851: 794: 763: 735: 711: 686: 659: 647:indiatimes.com 634: 542: 527: 506: 504: 501: 500: 499: 492: 486: 480: 474:Darbaker Prize 470: 464: 463:Humboldt Award 457: 450: 444: 438: 432: 425: 413: 410: 406:Annual Reviews 401:The Plant Cell 342:metalloenzymes 253: 250: 244:to synthesize 234:photosynthesis 214:Henry A. Lardy 185: 182: 165:metalloenzymes 148: 147: 128: 124: 123: 120: 119: 108: 102: 101: 92: 88: 87: 81: 80: 69: 65: 64: 58: 54: 53: 48: 32: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1676: 1665: 1662: 1660: 1657: 1655: 1652: 1650: 1647: 1645: 1644:Living people 1642: 1640: 1637: 1635: 1632: 1630: 1627: 1625: 1622: 1620: 1617: 1616: 1614: 1601: 1595: 1592: 1581: 1577: 1571: 1568: 1557: 1553: 1547: 1544: 1533: 1529: 1523: 1520: 1509: 1505: 1499: 1496: 1485: 1481: 1475: 1472: 1461: 1457: 1451: 1448: 1437: 1433: 1427: 1424: 1413: 1409: 1403: 1400: 1389: 1385: 1379: 1376: 1371: 1367: 1361: 1358: 1346: 1342: 1337: 1332: 1328: 1324: 1320: 1316: 1312: 1308: 1304: 1297: 1294: 1282: 1278: 1274: 1270: 1266: 1259: 1256: 1245: 1241: 1235: 1233: 1229: 1217: 1216:Berkeley News 1213: 1207: 1204: 1193: 1189: 1183: 1180: 1169: 1165: 1159: 1156: 1151: 1147: 1142: 1137: 1133: 1129: 1124: 1119: 1115: 1111: 1107: 1103: 1099: 1092: 1089: 1084: 1080: 1075: 1070: 1066: 1062: 1058: 1054: 1050: 1046: 1042: 1038: 1034: 1027: 1024: 1013: 1009: 1003: 1001: 997: 992: 988: 984: 980: 976: 972: 968: 964: 956: 953: 948: 944: 940: 936: 932: 928: 924: 920: 912: 909: 904: 900: 895: 890: 886: 882: 878: 874: 870: 866: 862: 855: 852: 847: 843: 838: 833: 829: 825: 821: 817: 813: 809: 805: 798: 795: 790: 786: 782: 778: 774: 767: 764: 753: 746: 739: 736: 725: 721: 715: 712: 700: 699:Berkeley News 696: 690: 687: 676: 672: 666: 664: 660: 648: 644: 638: 635: 630: 626: 621: 616: 612: 608: 603: 598: 594: 590: 586: 582: 578: 571: 569: 567: 565: 563: 561: 559: 557: 555: 553: 551: 549: 547: 543: 540: 536: 531: 528: 525: 521: 517: 511: 508: 502: 497: 493: 491: 487: 485: 481: 479: 475: 471: 469: 465: 462: 458: 455: 451: 449: 445: 443: 439: 437: 433: 430: 426: 423: 419: 418: 417: 411: 409: 407: 403: 402: 397: 396: 391: 386: 384: 380: 376: 372: 367: 365: 364:Infosys Prize 361: 357: 353: 349: 348: 347:Chlamydomonas 343: 339: 336: 331: 326: 322: 317: 315: 314: 313:chlamydomonas 309: 305: 304:cytochrome c6 301: 297: 294: 293: 288: 283: 281: 277: 276: 275:Chlamydomonas 271: 267: 263: 259: 251: 249: 247: 243: 239: 235: 231: 230: 225: 224: 219: 215: 211: 207: 203: 202:United States 199: 195: 191: 183: 181: 179: 175: 172: 171: 170:Chlamydomonas 166: 162: 158: 157:plant biology 154: 145: 129: 125: 121: 114: 113: 109: 107: 103: 100: 96: 93: 89: 86: 82: 78: 73: 70: 66: 62: 59: 55: 51: 45:(age 65) 31: 27: 20: 1594: 1583:. 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Springer. 515: 510: 415: 399: 393: 387: 368: 345: 330:cytochrome c 318: 312: 296:plastocyanin 290: 284: 273: 255: 242:ATP synthase 227: 221: 187: 168: 152: 151: 110: 91:Institutions 84: 1639:1959 births 238:chloroplast 1613:Categories 1585:2019-05-23 1561:2019-05-23 1537:2019-05-23 1513:2019-05-23 1489:2019-05-23 1465:2019-05-23 1441:2019-05-23 1432:"Newsroom" 1417:2019-05-23 1393:2019-05-23 1249:2019-05-23 1222:2019-05-23 1197:2019-05-23 1173:2019-05-23 1017:2019-05-23 757:2019-05-23 729:2019-05-23 705:2019-05-23 680:2019-05-23 671:"MGM 2007" 653:2019-05-23 503:References 39:1959-08-31 1350:8 October 1327:1040-4651 1286:8 October 1132:0027-8424 1065:0036-8075 983:0006-2960 939:0022-2836 885:0261-4189 828:679283371 789:1471-9053 611:0027-8424 383:bioenergy 366:in 2017. 180:in 2012. 144:/merchant 1345:31628163 1150:19541628 1083:17932292 775:. 1976. 629:25675533 142:/Faculty 1336:6925020 1141:2700887 1110:Bibcode 1074:2875087 1045:Bibcode 1037:Science 991:8399201 947:7623381 903:2824187 846:3023849 620:4352817 589:Bibcode 392:of the 159:at the 127:Website 1412:Rediff 1343:  1333:  1325:  1148:  1138:  1130:  1081:  1071:  1063:  989:  981:  945:  937:  901:  894:553670 891:  883:  844:  837:367534 834:  826:  787:  627:  617:  609:  522:  472:2012, 280:copper 190:Mumbai 174:genome 117:(1983) 115:  106:Thesis 79:(2012) 74:(2006) 68:Awards 50:Mumbai 1275:(1). 748:(PDF) 459:2012 452:2010 446:2006 427:2004 420:1999 379:algae 140:/dept 136:.ucla 134:.chem 63:(PhD) 1484:ASPB 1460:ASPB 1436:UCLA 1388:ASPB 1352:2021 1341:PMID 1323:ISSN 1288:2021 1192:UCLA 1146:PMID 1128:ISSN 1079:PMID 1061:ISSN 987:PMID 979:ISSN 943:PMID 935:ISSN 899:PMID 881:ISSN 842:PMID 824:OCLC 785:ISSN 625:PMID 607:ISSN 520:ISBN 381:and 360:UCLA 352:PNAS 289:for 138:.edu 29:Born 1331:PMC 1315:doi 1277:doi 1136:PMC 1118:doi 1106:106 1069:PMC 1053:doi 1041:318 971:doi 927:doi 923:250 889:PMC 873:doi 832:PMC 816:doi 777:doi 752:NAS 615:PMC 597:doi 585:112 408:. 377:of 287:RNA 272:in 260:at 248:. 132:www 1615:: 1578:. 1554:. 1530:. 1506:. 1482:. 1458:. 1434:. 1410:. 1386:. 1368:. 1339:. 1329:. 1321:. 1311:31 1309:. 1305:. 1273:55 1271:. 1267:. 1242:. 1231:^ 1214:. 1190:. 1166:. 1144:. 1134:. 1126:. 1116:. 1104:. 1100:. 1077:. 1067:. 1059:. 1051:. 1039:. 1035:. 1010:. 999:^ 985:. 977:. 967:32 965:. 941:. 933:. 921:. 897:. 887:. 879:. 867:. 863:. 840:. 830:. 822:. 810:. 806:. 783:. 750:. 722:. 697:. 673:. 662:^ 645:. 623:. 613:. 605:. 595:. 583:. 579:. 545:^ 498:. 476:, 385:. 226:. 41:) 1602:. 1588:. 1564:. 1540:. 1516:. 1492:. 1468:. 1444:. 1420:. 1396:. 1372:. 1354:. 1317:: 1290:. 1279:: 1252:. 1225:. 1200:. 1176:. 1152:. 1120:: 1112:: 1085:. 1055:: 1047:: 1020:. 993:. 973:: 949:. 929:: 905:. 875:: 869:6 848:. 818:: 812:6 791:. 779:: 760:. 732:. 708:. 683:. 656:. 631:. 599:: 591:: 37:(

Index

Mumbai
University of Wisconsin–Madison
Gilbert Morgan Smith Medal
Member of the National Academy of Sciences
University of California, Berkeley
University of California, Los Angeles
Thesis
The Chlamydomonas reinhardi chloroplast coupling factor 1 : its purification, properties, and aspects of its synthesis in vivo
www.chem.ucla.edu/dept/Faculty/merchant
plant biology
University of California, Berkeley
metalloenzymes
Chlamydomonas
genome
National Academy of Sciences
Mumbai
J.B. Petit High School for Girls
St. Xavier's College
United States
University of Wisconsin–Madison
molecular biology
Henry A. Lardy
University of Wisconsin–Madison
Chlamydomonas reinhardtii
Chlamydomonas reinhardtii
photosynthesis
chloroplast
ATP synthase
adenosine triphosphate
Lawrence Bogorad

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