231:. This led to the discovery that the number of cell divisions the cell underwent was determined by internal counting mechanisms. This research also led to her indicating specific markers on progenitor cell lines and external signaling molecules that are involved in the maintenance of neural stem cells.
291:
in 2008. This award in considered a no-strings attached grant intended to supplement the winner's potential for creativity. Dr. Temple was also the recipient of the 2010 Citizen
Laureate Awards. This was awarded to her by The University at Albany Foundation for her research into treatments for
234:
Some of her other research has indicated that the limited success of embryonic stem cell transplants in neurological cases may be due to the introduction of cells at the wrong developmental stage. This may have a huge impact on neurological therapies using stem cells as a future of medicine.
258:
dependent stem cell cultures in a more efficient way. She also recently identified an important human central nervous stem cell that may lead to important developments in retinal disease treatments. In 2015, she attended a RPI stem cell and bioengineering meeting and spoke about her
177:
In 2010 she and John J. Nigro were recipients of the 2010 Citizen
Laureate Awards. This award is meant to recognize leaders in the fields of business, industry, government, and academia.
660:
263:(RPE) research. She discussed how her team has been furthering their research into culturing human retinal stem cells and the use of RPE cells in therapy for age-related
203:. Dr. Temple is married to Dr. Jeffrey Stern, a retinal surgeon, who is the other co-founder of the Regenerative Research Foundation and Neural Stem Cell Institute.
174:. She is the president and co-founder of StemCulture, LLC., a company created by scientists in order to create innovative products and promote scientific research.
625:
314:
Shen Q, Wang Y, Dimos JT, Fasano CA, Phoenix TN, Lemischka IR, Ivanova NB, Stifani S, Morrisey EE, Temple S. Nat
Neurosci. 2006 Jun;9(6):743-51. Epub 2006 May 7.
250:
As president of StemCulture, LLC. she is currently working on a new study involving a new product, StemBeads FGF2. StemCulture, LLC. describe this product as a
630:
524:
220:
Temple's current laboratory focuses primarily on neural stem cells and the development for therapies related to eye, brain, and spinal cord disorders.
306:
Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure.
640:
238:
She has also provided evidence in her field that has shown that progenitor cells gradually lose the ability to divide. She established that the
124:
Temple is also the principal investigator in her laboratory that focuses on neural stem cells and therapies for neurological-related disorders
525:"Speaker - Cell Symposia: Stem cells in modeling and treating disease, November 21 - 23, 2013 Cedars-Sinai Medical Center, Los Angeles, USA"
655:
645:
151:
research when she discovered that the embryonic mammalian brain contained a rare stem-like cell. After this discovery, she focused on
355:
635:
318:
LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1.
196:
181:
275:
Temple has a large number of patents related to neural stem cells and for various methods for culture undifferentiated cells.
284:
650:
260:
200:
532:
288:
137:
58:
44:
163:
620:
293:
192:
121:
89:
112:. She is a co-founder and scientific director for The Neural Stem Cell Institute and is a professor of
264:
133:
40:
141:
48:
208:
167:
247:
is important in this, because a reduction in its expression results in a delay in this process.
324:
Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells.
312:
The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.
171:
117:
420:"Stem Cell Researcher Made University at Albany Citizen Laureate - University at Albany-SUNY"
159:
152:
109:
224:
578:
330:
LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal.
105:
356:"Sally Temple, Ph.D., Scientific Director - Neural Stem Cell Institute, Rensselaer NY"
614:
251:
113:
79:
223:
One of her major accomplishments in her field is the isolation and culturing of a
158:
She has since been labelled an innovator in the field of stem cells, specifically
553:
554:"Sally Temple on adult RPEs for vision impairment, IND, & more - The Niche"
500:
228:
148:
476:
320:
Capela A, Temple S. Dev Biol. 2006 Mar 15;291(2):300-13. Epub 2006 Feb 3.
452:
390:
419:
579:"Patents by Inventor Sally Temple Stern - Justia Patents Database"
283:
In 2003 Dr. Temple received the Jacob Javitz Merit Award from the
244:
240:
255:
326:
Sun Y, Goderie SK, Temple S. Neuron. 2005 Mar 24;45(6):873-86.
605:
144:. Her focus at this time was on optic nerve development.
308:
Phoenix TN, Temple S. Genes Dev. 2010 Jan 1;24(1):45-56.
529:
www.cell-symposia-stemcells-modelingtreatingdisease.com
188:
332:
Capela A, Temple S. Neuron. 2002 Aug 29;35(5):865-75.
155:
and how they develop over time and produce progeny.
187:Temple currently is the scientific director of the
85:
75:
54:
36:
28:
21:
501:"You searched for stem beads fgf2 - StemCulture"
136:. She then continued her PhD education at the
8:
140:and competed her postdoctoral fellowship at
661:Members of the National Academy of Medicine
206:She is a member of the Editorial Board for
18:
360:Neural Stem Cell Institute, Rensselaer NY
147:Temple became a pioneer in the field of
342:
162:, which are potentially applicable in
626:Alumni of the University of Cambridge
453:"Sally Temple — MacArthur Foundation"
7:
447:
445:
443:
441:
439:
414:
412:
410:
385:
383:
381:
379:
377:
375:
350:
348:
346:
191:. She also is a faculty member for
180:Previously, she was a fellow of the
631:Alumni of University College London
14:
254:supplement that is able to grow
197:Rensselaer Polytechnic Institute
182:Alden March Bioethics Institute
641:American women neuroscientists
606:The Neural Stem Cell Institute
292:both macular degeneration and
132:Temple received her B.A. from
1:
477:"Jeffrey Stern - StemCulture"
104:is an American developmental
391:"Sally Temple - StemCulture"
285:National Institute of Health
261:retinal pigmented epithelial
656:21st-century American women
287:. She was then awarded the
677:
646:Columbia University alumni
189:Neural Stem Cell Institute
138:University College London
95:
68:
62:Jacob Javitz Merit Award
59:MacArthur Fellows Program
45:University College London
636:American neuroscientists
164:cell replacement therapy
16:American neuroscientist
193:Albany Medical College
122:Albany Medical College
90:Albany Medical College
64:Citizen Laureate Award
289:MacArthur Fellowship
265:macular degeneration
225:progenitor cell line
134:Cambridge University
41:Cambridge University
294:Parkinson's disease
142:Columbia University
49:Columbia University
583:patents.justia.com
209:Developmental Cell
168:spinal cord injury
166:for ailments like
651:MacArthur Fellows
172:neurodegeneration
160:neural stem cells
153:neural stem cells
118:Neuropharmacology
99:
98:
70:Scientific career
668:
593:
592:
590:
589:
575:
569:
568:
566:
565:
550:
544:
543:
541:
540:
531:. Archived from
521:
515:
514:
512:
511:
497:
491:
490:
488:
487:
473:
467:
466:
464:
463:
457:www.macfound.org
449:
434:
433:
431:
430:
416:
405:
404:
402:
401:
387:
370:
369:
367:
366:
352:
110:Albany, New York
19:
676:
675:
671:
670:
669:
667:
666:
665:
611:
610:
602:
597:
596:
587:
585:
577:
576:
572:
563:
561:
552:
551:
547:
538:
536:
523:
522:
518:
509:
507:
499:
498:
494:
485:
483:
475:
474:
470:
461:
459:
451:
450:
437:
428:
426:
418:
417:
408:
399:
397:
389:
388:
373:
364:
362:
354:
353:
344:
339:
302:
281:
273:
218:
130:
37:Alma mater
24:
17:
12:
11:
5:
674:
672:
664:
663:
658:
653:
648:
643:
638:
633:
628:
623:
613:
612:
609:
608:
601:
600:External links
598:
595:
594:
570:
560:. 17 June 2015
545:
516:
492:
468:
435:
424:www.albany.edu
406:
371:
341:
340:
338:
335:
334:
333:
327:
321:
315:
309:
301:
298:
280:
277:
272:
269:
217:
214:
129:
126:
106:neuroscientist
97:
96:
93:
92:
87:
83:
82:
77:
73:
72:
66:
65:
56:
52:
51:
38:
34:
33:
30:
26:
25:
22:
15:
13:
10:
9:
6:
4:
3:
2:
673:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
622:
621:Living people
619:
618:
616:
607:
604:
603:
599:
584:
580:
574:
571:
559:
555:
549:
546:
535:on 2015-11-20
534:
530:
526:
520:
517:
506:
502:
496:
493:
482:
478:
472:
469:
458:
454:
448:
446:
444:
442:
440:
436:
425:
421:
415:
413:
411:
407:
396:
392:
386:
384:
382:
380:
378:
376:
372:
361:
357:
351:
349:
347:
343:
336:
331:
328:
325:
322:
319:
316:
313:
310:
307:
304:
303:
299:
297:
295:
290:
286:
278:
276:
270:
268:
266:
262:
257:
253:
252:growth factor
248:
246:
243:
242:
236:
232:
230:
226:
221:
215:
213:
211:
210:
204:
202:
198:
194:
190:
185:
183:
178:
175:
173:
169:
165:
161:
156:
154:
150:
145:
143:
139:
135:
127:
125:
123:
119:
115:
111:
107:
103:
94:
91:
88:
84:
81:
78:
74:
71:
67:
63:
60:
57:
53:
50:
46:
42:
39:
35:
31:
27:
20:
586:. Retrieved
582:
573:
562:. Retrieved
557:
548:
537:. Retrieved
533:the original
528:
519:
508:. Retrieved
504:
495:
484:. Retrieved
480:
471:
460:. Retrieved
456:
427:. Retrieved
423:
398:. Retrieved
394:
363:. Retrieved
359:
329:
323:
317:
311:
305:
300:Publications
282:
274:
249:
239:
237:
233:
222:
219:
207:
205:
186:
179:
176:
157:
146:
131:
114:Neuroscience
102:Sally Temple
101:
100:
86:Institutions
80:Neuroscience
69:
61:
23:Sally Temple
505:StemCulture
481:StemCulture
395:StemCulture
201:SUNY Albany
29:Nationality
615:Categories
588:2015-11-20
564:2015-11-20
539:2015-11-20
510:2015-11-20
486:2015-11-20
462:2015-11-19
429:2015-11-19
400:2015-11-19
365:2015-11-19
337:References
558:The Niche
149:stem cell
216:Research
32:American
271:Patents
279:Awards
199:, and
76:Fields
55:Awards
241:Foxg1
256:FGF2
245:gene
229:glia
170:and
128:Life
116:and
227:of
120:at
108:in
617::
581:.
556:.
527:.
503:.
479:.
455:.
438:^
422:.
409:^
393:.
374:^
358:.
345:^
296:.
267:.
212:.
195:,
184:.
47:,
43:,
591:.
567:.
542:.
513:.
489:.
465:.
432:.
403:.
368:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.