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fabricating many of the data underlying his research. Reuben never conducted the clinical trials that he wrote about in 21 journal articles dating from at least 1996. In some cases, he even invented the patients. Although Reuben often co-wrote papers with other researchers, Baystate found that the other researchers did not know about or participate in Reuben's studies, and their names were forged on documents. The hospital asked the journals to retract the studies, which reported favorable results from painkillers including
305:. On May 24, Ponsor sentenced him to six months in prison, followed by three years of supervised release. He was ordered to pay a $ 5,000 fine, forfeit $ 50,000 to the government and make $ 360,000 in restitution to pharmaceutical companies. The plea deal effectively ended his career as a doctor; most states will not grant medical licenses to convicted felons.
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that published ten articles identified as containing fraudulent data. "His findings had a huge impact on the field." He also described Reuben's actions as the biggest case of fraud in the history of anesthesiology. Fellow editor Paul White believed that Reuben's fraudulent studies may have actually
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Reuben's fabricated data may have had impact beyond systematic review conclusions because they addressed topical questions for which anaesthetists, surgeons, and patients seek answers, such as the utility of multimodal anaesthesia, or whether non-steroidal anti-inflammatory drugs (NSAIDs) influence
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found that while some reviews were no longer valid when the Reuben studies were removed, the conclusions in the majority of them remained unchanged. The review found that the key Reuben claims that needed to be re-examined were "the absence of detrimental effects of coxibs on bone healing after
209:
Reuben fell under suspicion when
Baystate conducted a routine audit in May 2008 which revealed that Reuben had not been given approval for two studies that he intended to present during the hospital's research week. On March 10, 2009 a Baystate spokeswoman announced that Reuben admitted to
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spine surgery, the beneficial long-term outcome after preemptive administration of coxibs including an allegedly decreased incidence of chronic pain after surgery, and the analgesic efficacy of ketorolac or clonidine when added to local anesthetics for intravenous regional anesthesia."
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bone healing ... Millions of people have had NSAIDs after fractures, trauma or orthopaedic surgery without problems of bone healing. The plausibility of a sizeable negative effect of NSAIDs on bone healing has to be questioned.
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could be used as a painkiller. Pfizer gave Reuben five research grants between 2002 and 2007. He was a paid member of the company's speakers bureau, giving talks about Pfizer drugs to colleagues. Reuben also wrote to the
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surgeries. Reuben has now admitted that he never conducted any of the clinical trials on which his conclusions were based "in what may be considered the longest-running and widest-ranging cases of academic fraud."
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Reuben's work had actually come under scrutiny as early as 2007, when several anesthesiologists noticed his studies never showed negative results. Greg Koski, former director of the
301:. Prosecutors alleged that Reuben obtained thousands of dollars in grants for research that he never performed. He formally pleaded guilty on February 21, 2010 before Judge
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Tufts has since cut ties with Reuben, and his
Massachusetts medical license was permanently revoked after a period in which he voluntarily agreed not to practice.
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Dr. Scott Reuben, former chief of acute pain at
Baystate Medical Center in Springfield, pleads guilty to health-care fraud
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Six months in federal prison, three years' supervised release, $ 5,000 fine, forfeiture of $ 50,000, $ 360,000 restitution
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harmed patients due to the sale of "billions of dollars' worth of drugs" that caused slower recovery times.
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All of Reuben's 21 fraudulent articles, as well as the article abstracts, are documented in the magazine
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Scott Reuben, a former
Baystate doctor who faked research, sentenced to 6 months for health care fraud
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108:(born 1958) is an American anesthesiologist who falsified data heralding the benefits of the
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414:"Fraud Case Stuns Anesthesiologists Post-op Pain Expert Fabricated Years of Data"
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from
February 1991 until 2009 when he was sentenced to prison for healthcare
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684:"Fraud or flawed: adverse impact of fabricated or poor quality research"
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151:. Reuben was considered to be a prolific and influential researcher in
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On
January 7, 2010 Reuben agreed to plead guilty to one count of
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Doctor accused of faking studies; His work dealt with pain drugs
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387:"A Medical Madoff: Anesthesiologist Faked Data in 21 Studies"
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Top Pain
Scientist Fabricated Data in Studies, Hospital Says
253:"Doctors have been using (his) findings very widely," said
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chairman who was convicted of orchestrating a $ 65-billion
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Moore, R. A.; Derry, S.; McQuay, H. J. (17 March 2010).
615:
United States
Attorney for the District of Massachusetts
443:"Doctor Admits Pain Studies Were Frauds, Hospital Says"
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Anesthesiologist sentenced on health care fraud charge
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in 1985 and undertook his anesthesiology residency at
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765:People involved in scientific misconduct incidents
517:Mass. doctor accused of fabricating pain studies
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116:while downplaying its negative side effects.
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316:Reuben from assisting in drug applications.
170:has called Reuben the medical equivalent of
474:"Fraud Case Rocks Anesthesiology Community"
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775:Medical controversies in the United States
194:. He graduated from medical school at the
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356:List of scientific misconduct incidents
196:State University of New York at Buffalo
627:Scott S. Reuben: Debarment Order (FDA)
420:, vol. 35, no. 4, April 2009
273:Office for Human Research Protections
27:American anesthesiologist (born 1958)
7:
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441:Harris, Gardiner (March 11, 2009),
312:(FDA) issued an order permanently
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770:People convicted for health fraud
745:Ethics of science and technology
701:10.1111/j.1365-2044.2010.06295.x
641:Marret; et al. (Dec 2009).
77:Pleaded guilty February 24, 2010
643:"lessons from the Reuben case"
308:On November 16, 2011 the U.S.
1:
135:, Massachusetts and chief of
660:10.1097/ALN.0b013e3181c14c3d
310:Food and Drug Administration
248:Food and Drug Administration
760:Hoaxes in the United States
234:. His studies also claimed
43:1958 (age 65–66)
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740:Columbia University alumni
200:Mount Sinai Medical Center
145:Springfield, Massachusetts
336:In 2010 the editorial in
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559:Anesthesia and Analgesia
260:Anesthesia and Analgesia
330:evidence-based medicine
190:Reuben was educated at
141:Baystate Medical Center
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556:, Steven L. Shafer,
228:Merck & Co. Inc.
119:He was Professor of
554:"Retraction Notice"
542:Wall Street Journal
478:Anesthesiology News
418:Anesthesiology News
392:Scientific American
192:Columbia University
167:Scientific American
609:2011-05-31 at the
578:, January 15, 2010
562:, 20 February 2009
448:The New York Times
265:scientific journal
755:Hoaxes in science
328:articles used in
326:systematic review
324:A 2009 review of
299:health care fraud
284:Healthcare Ledger
159:during and after
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86:Health care fraud
16:(Redirected from
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112:pain medication
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735:1958 births
688:Anaesthesia
424:27 December
338:Anaesthesia
277:peer review
212:Pfizer Inc.
724:Categories
362:References
293:Sentencing
186:Background
161:orthopedic
137:acute pain
48:Occupation
314:debarring
279:process.
710:20402871
669:19934873
607:Archived
350:See also
220:Celebrex
114:Celebrex
750:Forgers
243:Effexor
92:Penalty
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320:Impact
224:Lyrica
216:Bextra
176:NASDAQ
133:Boston
110:Pfizer
236:Wyeth
232:Vioxx
149:fraud
706:PMID
665:PMID
456:2015
426:2015
401:2015
263:, a
226:and
222:and
157:pain
123:and
40:Born
696:doi
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