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42:
73:
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The species inhabits the grasslands of central Mexico, expanding north to the central and southwestern parts of New Mexico and southeastern parts of
Arizona. It prefers areas with dense grass, in which it makes navigational trails called runways that resemble a tunnel with a grass covering. It feeds
331:
In the case of HIV type-1, finding an animal with similar antibody response to the virus as humans can prove difficult. A study conducted in 1998 found that the tawny-bellied cotton rat can be infected by low-level HIV-1. A similar immune response to humans is activated on infection. The degree of
310:
The tawny-bellied cotton rat occurs in the same area as the closely related hispid cotton rat, with the former occupying the moister areas and the latter the more arid areas. When living in adjacent habitats, one species tends to become more numerous while the other maintains a smaller population.
335:
The species was found to undergo an equivalent infection to pulmonary tuberculosis as humans. This is an upgrade over the previous animal models of other small rodents and rabbits. Cotton rats combine the best traits of human-like lung granuloma formation (trait of rabbits) and inexpensive care
327:
The tawny-bellied cotton rat is used as a model organism to develop and test human pathogen treatments. It is affected by many of the same viral and bacterial infections that humans are susceptible to, which helps create vaccines and therapeutic treatments. Other factors that make the species a
293:
The fur is tawny on the belly (the origin of the species' common name), and black and tan speckled on the back. The fur body contains three types of hair: guard-awl hair, guard hair, and under hair. The guard hair is the longest with the guard-awl and under hair following in decreasing length.
277:
Sexual dimorphism is not present, but the adult male weighs slightly more than the female at 222 grams (7.8 oz) compared to 206 grams (7.3 oz). The tail has small scales and is covered in hair which distinguishes it from the larger scales of the closely related
336:(trait of other small rodents) to provide a suitable host for this type of study. Future research is underway to use the cotton rat for studying pulmonary tuberculosis complicated by HIV-1 due to similarities with humans in both diseases.
328:
desirable test subject are the existence of inbred strains, ease of handling, and inexpensive upkeep. Some of the diseases tested on the cotton rat are respiratory syncytial virus, and pulmonary tuberculosis, and HIV type-1.
307:
on grasses, specifically bunchgrass, which they also use in nest-building. Its range in central New Mexico is expanding westward due to an increase in precipitation and in temperature from climate change.
527:
Geluso, Keith; Hoffman, Justin D.; Ashe, Vikki A.; White, Jeremy A.; Bogan, Michael A. (2005). "Westward
Expansion of the Tawny-bellied Cotton Rat (Sigmodon fulviventer) in West-central New Mexico".
720:
Elwood, Robert L.; Wilson, Samuel; Blanco, Jorge C.G.; Yim, Kevin; Pletneva, Luba; Nikonenko, Boris; Samala, Rowena (2007). "The
American cotton rat: A novel model for pulmonary tuberculosis".
444:
Zelditch, Miriam L.; Carmichael, Christopher A. (1989). "Ontogenetic
Variation in Patterns of Developmental and Functional Integration in Skulls of Sigmodon fulviventer".
859:
937:
965:
668:"Effectiveness of topically administered neutralizing antibodies in experimental immunotherapy of respiratory syncytial virus infection in cotton rats"
833:
872:
332:
infection may be increased by altering the co-receptors on the animal's cells, which would improve the reliability of the test subject.
290:
is a short and broad rather than elongated skull. The dentition is marked by well-developed maxillary incisors and high-crowned molars.
975:
311:
Even though both species seem to avoid one another, there is a passive, indirect competition between the species. In
Durango, Mexico,
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are located on the face and have been observed to play a role in maintaining body position while swimming.
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565:
Petersen, Michael K. (1973). "Interaction
Between the Cotton Rats, Sigmodon fulviventer and S. hispidus".
202:
970:
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Musser, G. G.; Carleton, M. D. (2005). "Superfamily
Muroidea". In D. E. Wilson; D. M. Reeder (eds.).
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Ahi, Alwynelle S. (1982). "Evidence of use of vibrissae in swimming in
Sigmodon fulviventer".
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was found to be dominant, probably due to being a specialist compared to the generalist
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Prince, G.A.; Hemming, V.A.; Horswood, R.L.; Baron, P.A.; Chanock, R.M. (1987).
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609:"HIV type-1 infection of the cotton rat (Sigmodon fulviventer and S. hispidus)"
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Langley, Raymond J.; Prince, Gregory A.; Ginsberg, Harold S. (1998).
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Mammal
Species of the World: A Taxonomic and Geographic Reference
356:Álvarez-Castañeda, S.T.; Castro-Arellano, I.; Lacher, T. (2016).
825:
771:
763:. Baltimore: Johns Hopkins University Press. pp. 894–1531.
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10.1894/0038-4909(2005)050[0273:weottc]2.0.co;2
780:
286:). Another characteristic distinguishing it from
613:Proceedings of the National Academy of Sciences
381:10.2305/IUCN.UK.2016-2.RLTS.T20212A22355460.en
407:Baker, Rollin H.; Shump Jr., Karl A. (1978).
8:
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966:IUCN Red List least concern species
367:IUCN Red List of Threatened Species
25:
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684:10.1128/JVI.61.6.1851-1854.1987
567:The American Midland Naturalist
1:
501:10.1016/s0003-3472(82)80211-x
529:The Southwestern Naturalist
992:
734:10.1016/j.tube.2006.07.001
976:Mammals described in 1889
208:
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93:Scientific classification
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69:
60:
48:
39:
35:Tawny-bellied cotton rat
34:
634:10.1073/pnas.95.24.14355
302:Distribution and habitat
230:tawny-bellied cotton rat
409:"Sigmodon fulviventer"
374:: e.T20212A22355460.
812:Sigmodon fulviventer
782:Sigmodon fulviventer
360:Sigmodon fulviventer
235:Sigmodon fulviventer
212:Sigmodon fulviventer
18:Sigmodon fulviventer
672:Journal of Virology
625:1998PNAS...9514355L
619:(24): 14355–14360.
551:– via BioOne.
194:S. fulviventer
63:Conservation status
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952:
774:Taxon identifiers
413:Mammalian Species
323:As a model animal
284:Sigmodon hispidus
280:hispid cotton rat
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27:Species of rodent
16:(Redirected from
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203:Binomial name
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971:Cotton rats
925:NatureServe
847:iNaturalist
806:Wikispecies
415:(94): 1–4.
387:12 November
317:S. hispidus
288:S. hispidus
273:Description
257:and in the
166:Subfamily:
960:Categories
340:References
267:New Mexico
261:states of
248:Cricetidae
219:J.A. Allen
160:Cricetidae
446:Evolution
188:Species:
116:Kingdom:
110:Eukaryota
56:, Mexico
930:2.105544
917:13000915
865:11420551
797:Q1769782
791:Wikidata
742:16973421
549:84364788
509:54240560
474:28564197
296:Whiskers
252:found in
250:. It is
181:Sigmodon
156:Family:
150:Rodentia
140:Mammalia
130:Chordata
126:Phylum:
120:Animalia
106:Domain:
83:IUCN 3.1
904:1002744
839:2438153
702:3553614
653:9826704
621:Bibcode
587:2424456
466:2409309
431:3503788
263:Arizona
240:species
238:) is a
176:Genus:
146:Order:
136:Class:
81: (
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255:Mexico
244:rodent
221:, 1889
943:89246
891:20212
860:IRMNG
852:44905
644:24377
583:JSTOR
545:S2CID
505:S2CID
462:JSTOR
427:JSTOR
938:NCBI
886:IUCN
873:ITIS
834:GBIF
738:PMID
698:PMID
649:PMID
470:PMID
389:2021
372:2016
265:and
228:The
912:MSW
899:MDD
821:EoL
730:doi
688:PMC
680:doi
639:PMC
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