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The prognosis for silent hypoxia in COVID-19 is generally poor, as oxygen levels in the blood can drop below 50 percent without being noticed. In cases where a healthy person was exposed to a hypoxic environment, the outcome will usually depend on the extent of associated tissue damage incurred. In
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A tool used to diagnose silent hypoxia is the six-minute walk test, (6MWT), wherein a patient walks at a normal pace for six minutes, in order to monitor their physiological response. It has been proven that, after performing the 6MWT, COVID-19 patients were more likely to develop exercise-induced
215:
Treatment depends on the cause. In some cases supplementary oxygen is needed, in severe cases artificial ventilation may be necessary. In mild cases where the cause was hypoxic breathing gas, it may only be necessary to return to a normally oxygenated environment. Underlying medical problems may
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affecting the blood flow of the lungs' airways, in addition to the blood vessels within the lungs, which must match in order to allow proper airflow, but not affecting them enough to cause shortness of breath. It is also speculated that silent hypoxia may be caused by the formation of small
125:
within the lungs. It has been shown that the breathing rates of patients with COVID-19 gradually increase, which in turn leads to silent hypoxia. It has also been shown that COVID-19 patients experience lesser levels of shortness of breath after exercise than non-COVID-19 patients.
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One theory relating to COVID-19 presentation suggests the impaired processing of severe hypoxia and resumption of normal breathing may be due to the neurological pathway by which the virus spreads from the oral cavity to the brain. It is speculated that this condition is caused by
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In healthy people this presentation can occur when the person breathes a gas which has a low oxygen content, and also a low carbon dioxide content, so there is no
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706:
Sirohiya, Prashant, et al. “Silent
Hypoxia in Coronavirus Disease-2019: Is It More Dangerous?-a Retrospective Cohort Study.” Lung India, 2021,
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Sellers, Steven H. (2016). "An
Overview of Rebreathers in Scientific Diving 1998–2013". In Pollock, N.W.; Sellers, S.H.; Godfrey, J.M. (eds.).
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1013:"Pulse Oximetry for Monitoring Patients with COVID-19 at Home. Potential Pitfalls and Practical Guidance"
721:"Silent Hypoxia Typically Not the First Symptom of COVID-19, Other Early Symptoms Should Be Monitored"
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reported: "A vast majority of Covid pneumonia patients I met had remarkably low oxygen saturations at
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186:—seemingly incompatible with life—but they were using their cellphones as we put them on monitors."
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612:"'Silent Hypoxia' Is Making Some Coronavirus Patients Critically Ill—Here's Why It's So Dangerous"
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154:. Cases of silent hypoxia with COVID-19 have been reported for patients who did not experience
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Brouqui P, Amrane S, Million M, Cortaredona S, Parola P, Lagier JC, Raoult D (January 2021).
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mild cases a quick return to normal follows reversion to normally oxygenated breathing gas.
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146:, the arterial and general tissue oxygen levels can drop without any initial warning. The
1203:"Early Detection of Silent Hypoxia in Covid-19 Pneumonia Using Smartphone Pulse Oximetry"
686:. Proceedings of NPS/NOAA/DAN/AAUS Workshop, 16–19 June 2015. Durham, NC. pp. 5–39.
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561:"COVID-19 patients with respiratory failure: what can we learn from aviation medicine?"
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Fuglebjerg NJ, Jensen TO, Hoyer N, Ryrsø CK, Lindegaard B, Harboe ZB (October 2020).
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Fuglebjerg NJ, Jensen TO, Hoyer N, Ryrsø CK, Lindegaard B, Harboe ZB (October 2020).
167:
159:
1028:
470:"Silent hypoxia: a frequently overlooked clinical entity in patients with COVID-19"
434:
414:
540:"What is 'silent hypoxia'? The coronavirus symptom patients don't know they have"
954:"Silent hypoxia in patients with SARS CoV-2 infection before hospital discharge"
849:"Silent hypoxia in patients with SARS CoV-2 infection before hospital discharge"
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389:"Silent hypoxia: Covid-19 patients who should be gasping for air but aren't"
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1152:"Caution against precaution: A case report on silent hypoxia in COVID-19"
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143:
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1062:"Covid-19: Patients to use pulse oximetry at home to spot deterioration"
824:"They don't struggle to breathe—but COVID-19 is starving them of oxygen"
762:"COVID-19 complications: Silent hypoxia emerges as new killer in Kerala"
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1076:
1061:
901:"Opinion | The Infection That's Silently Killing Coronavirus Patients"
410:"'Silent hypoxia' may be killing COVID-19 patients. But there's hope"
183:
1101:"Asymptomatic hypoxia in COVID-19 is associated with poor outcome"
803:"Blood clots in the lung may be a major cause of COVID-19 deaths"
203:. The condition can also be first detected by using prehospital
468:
Chandra A, Chakraborty U, Pal J, Karmakar P (September 2020).
393:
275:
1150:
Lari A, Alherz M, Nouri A, Botras L, Taqi S (December 2020).
519:"The Infection That's Silently Killing Coronavirus Patients"
344:
American
Journal of Respiratory and Critical Care Medicine
340:"Why COVID-19 Silent Hypoxemia Is Baffling to Physicians"
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had depressed to such a degree that they were at risk of
742:"Three reasons why coronavirus can cause silent hypoxia"
292:
1257:
Impact of the COVID-19 pandemic on other health issues
782:"Study explains why Covid-19 can cause silent hypoxia"
178:
opinion piece (April 20, 2020), emergency room doctor
430:"Three reasons why COVID-19 can cause silent hypoxia"
91:. This presentation is known to be a complication of
633:"Your Captain Speaking: Silent Hypoxia and COVID-19"
451:"Silent hypoxia and its role in COVID-19 detection"
58:
38:
24:
320: – Medical condition of oxygen deprivation
894:
892:
8:
1105:International Journal of Infectious Diseases
958:International Journal of Infectious Diseases
853:International Journal of Infectious Diseases
199:symptoms than non-COVID-19 patients who had
708:https://doi.org/10.1101/2021.08.26.21262668
338:Tobin MJ, Laghi F, Jubran A (August 2020).
16:Type of presentation of generalised hypoxia
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1017:Annals of the American Thoracic Society
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1011:Luks AM, Swenson ER (September 2020).
7:
216:require assessment and treatment.
14:
680:Rebreathers and Scientific Diving
653:"Rebreathers guide for beginners"
260:involving asphyxiant environments
279:
899:Levitan, Richard (2020-04-20).
1156:Annals of Medicine and Surgery
1060:Torjesen I (27 October 2020).
1029:10.1513/AnnalsATS.202005-418FR
566:British Journal of Anaesthesia
1:
233:Known to be associated with:
201:idiopathic pulmonary fibrosis
801:Srivastava A (23 May 2020).
740:Gupta J (20 November 2020).
87:that does not coincide with
517:Levitan R (20 April 2020).
1278:
1219:10.1007/s10916-020-01587-6
1207:Journal of Medical Systems
1169:10.1016/j.amsu.2020.11.007
1118:10.1016/j.ijid.2020.10.067
971:10.1016/j.ijid.2020.07.014
865:10.1016/j.ijid.2020.07.014
408:Pappas S (23 April 2020).
356:10.1164/rccm.202006-2157CP
164:acute respiratory distress
131:hypercapnic alarm response
938:American Lung Association
822:Wei-Haas M (8 May 2020).
726:American Lung Association
579:10.1016/j.bja.2020.04.012
29:
538:Bowden O (12 May 2020).
387:LaMotte S (7 May 2020).
158:or coughing until their
486:10.1136/bcr-2020-237207
449:Emily H (3 June 2020).
95:, and is also known in
933:"Six-Minute Walk Test"
767:The New Indian Express
631:Blanchet D, Greene S.
258:Occupational accidents
253:Inert gas asphyxiation
45:Critical care medicine
1262:Respiratory diseases
1201:Teo J (June 2020).
829:National Geographic
790:. 30 November 2020.
559:Ottestad W (2020).
438:. 19 November 2020.
318:Generalized hypoxia
156:shortness of breath
89:shortness of breath
905:The New York Times
524:The New York Times
291:. You can help by
243:Atypical pneumonia
49:infectious disease
1077:10.1136/bmj.m4151
693:978-0-9800423-9-9
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238:Altitude sickness
150:may show diffuse
105:rebreather diving
101:altitude sickness
97:walking pneumonia
83:) is generalised
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69:altitude sickness
19:Medical condition
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79:(also known as
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770:. 7 June 2020.
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729:. 15 May 2020.
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168:organ failure
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160:oxygen levels
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81:happy hypoxia
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916:. Retrieved
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834:the original
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660:. Retrieved
657:apdiving.com
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435:ScienceDaily
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293:adding to it
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266:malfunctions
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229:Epidemiology
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137:Presentation
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114:
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60:Risk factors
1162:: 301–303.
1111:: 233–238.
964:: 100–101.
859:: 100–101.
787:The Tribune
545:Global News
166:(ARDS) and
148:chest x-ray
123:blood clots
53:pulmonology
1251:Categories
1213:(8): 134.
918:2020-04-22
325:References
264:Rebreather
118:SARS-CoV-2
1086:225078120
1070:: m4151.
998:220530080
913:0362-4331
808:The Hindu
638:EMS World
272:accidents
220:Prognosis
211:Treatment
190:Diagnosis
152:pneumonia
40:Specialty
1237:32562006
1188:33169089
1137:33130200
1047:32521167
990:32663601
883:32663601
597:32362340
504:32900744
374:32539537
312:See also
248:COVID-19
195:hypoxia
144:COVID-19
93:COVID-19
65:COVID-19
1228:7305055
1179:7640922
1128:7604151
1067:The BMJ
1038:7462317
981:7836996
874:7836996
588:7165289
495:7478026
365:7397783
197:without
85:hypoxia
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662:11 May
617:Health
595:
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492:
372:
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184:triage
111:Causes
103:, and
1082:S2CID
994:S2CID
684:(PDF)
172:In a
1233:PMID
1184:PMID
1133:PMID
1043:PMID
986:PMID
909:ISSN
879:PMID
688:ISBN
664:2021
593:PMID
500:PMID
370:PMID
1223:PMC
1215:doi
1174:PMC
1164:doi
1123:PMC
1113:doi
1109:102
1072:doi
1033:PMC
1025:doi
976:PMC
966:doi
869:PMC
861:doi
583:PMC
575:doi
571:125
490:PMC
482:doi
394:CNN
360:PMC
352:doi
348:202
295:.
142:In
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
