Knowledge (XXG)

Small nuclear ribonucleoprotein polypeptide A

Source πŸ“

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Schonk D, van Dijk P, Riegmann P, Trapman J, Holm C, Willcocks TC, Sillekens P, van Venrooij W, Wimmer E, Geurts van Kessel A (January 1991). "Assignment of seven genes to distinct intervals on the midportion of human chromosome 19q surrounding the myotonic dystrophy gene region".
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Varani L, Gunderson SI, Mattaj IW, Kay LE, Neuhaus D, Varani G (April 2000). "The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein".
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Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M (September 1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex".
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Nelissen RL, Sillekens PT, Beijer RP, Geurts van Kessel AH, van Venrooij WJ (June 1991). "Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein".
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Avis JM, Allain FH, Howe PW, Varani G, Nagai K, Neuhaus D (March 1996). "Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding".
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Oubridge C, Ito N, Evans PR, Teo CH, Nagai K (December 1994). "Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin".
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Allain FH, Gubser CC, Howe PW, Nagai K, Neuhaus D, Varani G (April 1996). "Specificity of ribonucleoprotein interaction determined by RNA folding during complex formulation".
2429: 575: 474: 2714: 2414: 1537:"RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins" 2884: 2874: 2869: 2849: 2384: 2800: 2564: 1661:
Nagai K, Oubridge C, Jessen TH, Li J, Evans PR (December 1990). "Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A".
2519: 2069:"The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor" 1912:
Lu J, Hall KB (August 1997). "Tertiary structure of RBD2 and backbone dynamics of RBD1 and RBD2 of the human U1A protein determined by NMR spectroscopy".
1031: 1012: 397: 2759: 2155:"Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation" 2408:: THE NMR STRUCTURE OF THE 38KDA U1A PROTEIN-PIE RNA COMPLEX REVEALS THE BASIS OF COOPERATIVITY IN REGULATION OF POLYADENYLATION BY HUMAN U1A PROTEIN 2912: 3090: 3066: 3085: 2334: 1413: 1395: 2474: 2459: 2444: 52: 561: 2859: 2854: 1247: 2678:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutation, cleaved in Imidazole and Mg2+ solutions 1254: 538: 2279:"Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators" 2793: 1467: 2648:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutation, in Imidazole and Sr2+ solution 1382: 1361: 2558:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutation, in Cobalt Hexammine solution 460: 435: 1378: 2579: 1357: 2753:: Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) 377: 2369: 2354: 1708:"cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins" 3003: 2786: 1329: 574: 473: 3059: 2153:
Klein Gunnewiek JM, Hussein RI, van Aarssen Y, Palacios D, de Jong R, van Venrooij WJ, Gunderson SI (March 2000).
567: 466: 2693:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutation, in Sr2+ solution 2633:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutation, in Ba2+ solution 2603:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutation, in EDTA solution 2327: 2618:: Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaiton, and Mn2+ bound 1076: 385: 2022:
FerrΓ©-D'AmarΓ© AR, Zhou K, Doudna JA (October 1998). "Crystal structure of a hepatitis delta virus ribozyme".
2504: 1057: 2236:"Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" 1483:"Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" 2112:"An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins" 3052: 2738:: Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ 449: 2708:: Crystal structure of a group I intron/two exon complex that includes all catalytic metal ion ligands. 2663:: Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution 2320: 2031: 1846: 1758: 1670: 1548: 364: 2987: 2895: 2809: 1226: 1222: 1171: 1167: 1620:"Identification of molecular contacts between the U1 A small nuclear ribonucleoprotein and U1 RNA" 2222: 2055: 2010: 1870: 1782: 1694: 409: 1230: 1201: 1175: 1146: 2543:: Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution 2977: 2813: 2300: 2265: 2214: 2184: 2141: 2098: 2047: 2002: 1972: 1929: 1900: 1862: 1825: 1774: 1737: 1686: 1649: 1606: 1576: 1512: 1449: 357: 45: 3036: 2498:: U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix 2290: 2255: 2247: 2206: 2174: 2166: 2131: 2123: 2088: 2080: 2039: 1994: 1962: 1954: 1921: 1892: 1854: 1815: 1807: 1766: 1727: 1719: 1678: 1639: 1631: 1598: 1566: 1556: 1502: 1494: 1441: 654: 585: 529: 484: 1796:"NMR studies of U1 snRNA recognition by the N-terminal RNP domain of the human U1A protein" 812: 405: 2778: 629: 2035: 1850: 1762: 1674: 1552: 2136: 2111: 2093: 2068: 1967: 1942: 1811: 1723: 1635: 28: 2295: 2278: 2260: 2235: 2179: 2154: 1820: 1795: 1732: 1707: 1644: 1619: 1507: 1482: 946: 941: 936: 931: 915: 910: 905: 900: 884: 879: 874: 869: 864: 859: 854: 3079: 3032: 1602: 1571: 1536: 841: 2226: 2170: 389: 2059: 1874: 1786: 1698: 647: 426: 2438:: Crystal structure of a hairpin ribozyme in the catalytically-active conformation 2014: 413: 1418:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
2723:: Structural investigation of the GlmS ribozyme bound to its catalytic cofactor 2423:: RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES 2251: 1958: 1541:
Proceedings of the National Academy of Sciences of the United States of America
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Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (December 2000).
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Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (December 2000).
976: 790: 668: 613: 600: 512: 499: 401: 2304: 2269: 2218: 2188: 2145: 1896: 1561: 1516: 2127: 2102: 2051: 2006: 1976: 1933: 1904: 1866: 1829: 1778: 1741: 1690: 1653: 1610: 1580: 1453: 1294: 1289: 2967: 2393:: U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX 1278: 1121: 1102: 2920: 2902: 2891: 2067:
Lutz CS, Cooke C, O'Connor JP, Kobayashi R, Alwine JC (December 1998).
1310: 1088: 1043: 1943:"Structural basis of the RNA-binding specificity of human U1A protein" 1925: 1445: 334: 330: 326: 322: 318: 314: 310: 306: 302: 298: 294: 290: 286: 282: 278: 274: 270: 266: 262: 258: 254: 250: 246: 242: 238: 234: 230: 226: 222: 218: 214: 210: 206: 202: 198: 194: 190: 186: 182: 178: 174: 170: 166: 162: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 110: 106: 102: 98: 94: 90: 86: 82: 78: 74: 2935: 2930: 2925: 2864: 2844: 2834: 2573:: CRYSTAL STRUCTURE OF A SELF-SPLICING GROUP I INTRON WITH BOTH EXONS 1858: 1770: 1706:
Sillekens PT, Habets WJ, Beijer RP, van Venrooij WJ (December 1987).
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Jessen TH, Oubridge C, Teo CH, Pritchard C, Nagai K (November 1991).
1262: 998: 3020: 2528:: Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound 2879: 2839: 2821: 2210: 2043: 1535:
Hoffman DW, Query CC, Golden BL, White SW, Keene JD (March 1991).
1468:"Entrez Gene: SNRPA small nuclear ribonucleoprotein polypeptide A" 1333: 1998: 961: 957: 3028: 1328:
Small nuclear ribonucleoprotein polypeptide A has been shown to
1317: 381: 368:, Mud1, U1-A, U1A, Small nuclear ribonucleoprotein polypeptide A 2782: 2768:: RNA BINDING DOMAIN 2 OF HUMAN U1A PROTEIN, NMR, 20 STRUCTURES 2316: 821: 2312: 1941:
Allain FH, Howe PW, Neuhaus D, Varani G (September 1997).
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Howe PW, Nagai K, Neuhaus D, Varani G (August 1994).
802: 2996: 2976: 2960: 2944: 2911: 2820: 2483:: Transition State Stabilization by a Catalytic RNA 2468:: Transition State Stabilization by a Catalytic RNA 2453:: Transition State Stabilization by a Catalytic RNA 1215: 1194: 1160: 1139: 1374: 1372: 1370: 1353: 1351: 1349: 2277:Simmons A, Aluvihare V, McMichael A (June 2001). 584: 483: 16:Protein-coding gene in the species Homo sapiens 1379:GRCm38: Ensembl release 89: ENSMUSG00000061479 3060: 2794: 2328: 8: 1358:GRCh38: Ensembl release 89: ENSG00000077312 3067: 3053: 2801: 2787: 2779: 2335: 2321: 2313: 972: 837: 625: 524: 421: 63: 2294: 2259: 2178: 2135: 2092: 1966: 1819: 1731: 1643: 1570: 1560: 1506: 2350: 1345: 18: 589: 550: 545: 488: 447: 442: 7: 3017: 3015: 2110:Hetzer M, Mattaj IW (January 2000). 1307:U1 small nuclear ribonucleoprotein A 2588:: U1A MUTANT/RNA COMPLEX + GLYCEROL 3039:. You can help Knowledge (XXG) by 1812:10.1002/j.1460-2075.1994.tb06698.x 1724:10.1002/j.1460-2075.1987.tb02721.x 1636:10.1002/j.1460-2075.1991.tb04909.x 1212: 1191: 1157: 1136: 1112: 1093: 1067: 1048: 1022: 1003: 937:regulation of mRNA polyadenylation 807: 725: 663: 642: 14: 1313:that in humans is encoded by the 3019: 2758: 2743: 2728: 2713: 2698: 2683: 2668: 2653: 2638: 2623: 2608: 2593: 2578: 2563: 2548: 2533: 2518: 2503: 2488: 2473: 2458: 2443: 2428: 2413: 2398: 2383: 2378:: HEPATITIS DELTA VIRUS RIBOZYME 2368: 2363:: U1A-UTRRNA, NMR, 31 STRUCTURES 2353: 811: 573: 566: 560: 537: 472: 465: 459: 434: 27: 2171:10.1128/MCB.20.6.2209-2217.2000 3091:Human chromosome 19 gene stubs 2159:Molecular and Cellular Biology 1434:Cytogenetics and Cell Genetics 947:mRNA splicing, via spliceosome 822:More reference expression data 791:More reference expression data 1: 2296:10.1016/S1074-7613(01)00158-3 558: 457: 3086:Genes on human chromosome 19 1885:Journal of Molecular Biology 1603:10.1016/0378-1119(91)90077-O 3004:Signal recognition particle 2116:The Journal of Cell Biology 707:right lobe of thyroid gland 3107: 3014: 683:mucosa of transverse colon 2348: 2199:Nature Structural Biology 2085:10.1017/S1355838298981183 1414:"Mouse PubMed Reference:" 1396:"Human PubMed Reference:" 1293: 1288: 1284: 1277: 1261: 1242: 1219: 1198: 1187: 1164: 1143: 1132: 1119: 1115: 1100: 1096: 1087: 1074: 1070: 1055: 1051: 1042: 1029: 1025: 1010: 1006: 997: 982: 975: 971: 955: 885:identical protein binding 840: 836: 819: 810: 801: 788: 737: 728: 675: 666: 636: 628: 624: 607: 594: 557: 536: 527: 523: 506: 493: 456: 433: 424: 420: 375: 372: 362: 355: 350: 71: 66: 49: 44: 39: 35: 26: 21: 2252:10.1093/emboj/19.23.6569 1959:10.1093/emboj/16.18.5764 1499:10.1093/emboj/19.23.6569 1248:Chr 19: 40.75 – 40.77 Mb 2978:Vault ribonucleoprotein 860:snRNA stem-loop binding 1897:10.1006/jmbi.1996.0171 1562:10.1073/pnas.88.6.2495 1255:Chr 7: 26.89 – 26.9 Mb 2513:: U1A RNP DOMAIN 1-95 2128:10.1083/jcb.148.2.293 450:Chromosome 19 (human) 901:spliceosomal complex 875:nucleic acid binding 552:Chromosome 7 (mouse) 67:List of PDB id codes 40:Available structures 2988:Major vault protein 2945:Other transcription 2896:U1 spliceosomal RNA 2810:RNA-binding protein 2036:1998Natur.395..567F 1851:1996Natur.380..646A 1763:1994Natur.372..432O 1675:1990Natur.348..515N 1553:1991PNAS...88.2495H 765:ganglionic eminence 695:canal of the cervix 679:ganglionic eminence 3027:This article on a 2814:Ribonucleoproteins 1077:ENSMUSG00000061479 925:Biological process 894:Cellular component 848:Molecular function 3048: 3047: 3012: 3011: 2776: 2775: 1926:10.1021/bi9709811 1920:(34): 10393–405. 1446:10.1159/000132946 1304: 1303: 1300: 1299: 1273: 1272: 1238: 1237: 1209: 1208: 1183: 1182: 1154: 1153: 1128: 1127: 1109: 1108: 1083: 1082: 1064: 1063: 1038: 1037: 1019: 1018: 967: 966: 832: 831: 828: 827: 797: 796: 784: 783: 722: 721: 620: 619: 519: 518: 414:SNRPA - orthologs 346: 345: 342: 341: 50:Ortholog search: 3098: 3069: 3062: 3055: 3023: 3016: 2803: 2796: 2789: 2780: 2762: 2747: 2732: 2717: 2702: 2687: 2672: 2657: 2642: 2627: 2612: 2597: 2582: 2567: 2552: 2537: 2522: 2507: 2492: 2477: 2462: 2447: 2432: 2417: 2402: 2387: 2372: 2357: 2337: 2330: 2323: 2314: 2308: 2298: 2273: 2263: 2240:The EMBO Journal 2230: 2192: 2182: 2149: 2139: 2106: 2096: 2063: 2030:(6702): 567–74. 2018: 1980: 1970: 1947:The EMBO Journal 1937: 1908: 1878: 1859:10.1038/380646a0 1845:(6575): 646–50. 1833: 1823: 1800:The EMBO Journal 1790: 1771:10.1038/372432a0 1745: 1735: 1712:The EMBO Journal 1702: 1683:10.1038/348515a0 1669:(6301): 515–20. 1657: 1647: 1624:The EMBO Journal 1614: 1584: 1574: 1564: 1521: 1520: 1510: 1487:The EMBO Journal 1478: 1472: 1471: 1464: 1458: 1457: 1428: 1422: 1421: 1410: 1404: 1403: 1392: 1386: 1376: 1365: 1355: 1286: 1285: 1257: 1250: 1233: 1213: 1204: 1192: 1188:RefSeq (protein) 1178: 1158: 1149: 1137: 1113: 1094: 1068: 1049: 1023: 1004: 973: 880:U1 snRNP binding 855:U1 snRNA binding 838: 824: 815: 808: 793: 761:genital tubercle 749:ventricular zone 733: 731:Top expressed in 726: 711:popliteal artery 691:ventricular zone 671: 669:Top expressed in 664: 643: 626: 616: 603: 592: 577: 570: 564: 553: 541: 525: 515: 502: 491: 476: 469: 463: 452: 438: 422: 416: 367: 360: 337: 64: 58: 37: 36: 31: 19: 3106: 3105: 3101: 3100: 3099: 3097: 3096: 3095: 3076: 3075: 3074: 3073: 3013: 3008: 2992: 2979: 2972: 2956: 2940: 2907: 2816: 2807: 2777: 2772: 2769: 2763: 2754: 2748: 2739: 2733: 2724: 2718: 2709: 2703: 2694: 2688: 2679: 2673: 2664: 2658: 2649: 2643: 2634: 2628: 2619: 2613: 2604: 2598: 2589: 2583: 2574: 2568: 2559: 2553: 2544: 2538: 2529: 2523: 2514: 2508: 2499: 2493: 2484: 2478: 2469: 2463: 2454: 2448: 2439: 2433: 2424: 2418: 2409: 2403: 2394: 2388: 2379: 2373: 2364: 2358: 2344: 2341: 2311: 2276: 2246:(23): 6569–81. 2233: 2195: 2152: 2109: 2066: 2021: 1987:Nature Genetics 1983: 1953:(18): 5764–72. 1940: 1911: 1881: 1836: 1806:(16): 3873–81. 1793: 1757:(6505): 432–8. 1748: 1705: 1660: 1630:(11): 3447–56. 1617: 1587: 1534: 1530: 1528:Further reading 1525: 1524: 1493:(23): 6569–81. 1480: 1479: 1475: 1466: 1465: 1461: 1430: 1429: 1425: 1412: 1411: 1407: 1394: 1393: 1389: 1377: 1368: 1356: 1347: 1342: 1326: 1295:View/Edit Mouse 1290:View/Edit Human 1253: 1246: 1243:Location (UCSC) 1229: 1225: 1221: 1200: 1174: 1170: 1166: 1145: 1058:ENSG00000077312 951: 932:mRNA processing 920: 889: 865:protein binding 820: 789: 780: 775: 771: 767: 763: 759: 755: 751: 747: 743: 729: 718: 715:tibial arteries 713: 709: 705: 701: 697: 693: 689: 685: 681: 667: 611: 598: 590: 580: 579: 578: 571: 551: 528:Gene location ( 510: 497: 489: 479: 478: 477: 470: 448: 425:Gene location ( 376: 363: 356: 73: 51: 17: 12: 11: 5: 3104: 3102: 3094: 3093: 3088: 3078: 3077: 3072: 3071: 3064: 3057: 3049: 3046: 3045: 3024: 3010: 3009: 3007: 3006: 3000: 2998: 2994: 2993: 2991: 2990: 2984: 2982: 2974: 2973: 2971: 2970: 2964: 2962: 2958: 2957: 2955: 2954: 2948: 2946: 2942: 2941: 2939: 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1531: 1529: 1526: 1523: 1522: 1473: 1459: 1423: 1405: 1387: 1366: 1344: 1343: 1341: 1338: 1325: 1322: 1302: 1301: 1298: 1297: 1292: 1282: 1281: 1275: 1274: 1271: 1270: 1268: 1266: 1259: 1258: 1251: 1244: 1240: 1239: 1236: 1235: 1217: 1216: 1210: 1207: 1206: 1196: 1195: 1189: 1185: 1184: 1181: 1180: 1162: 1161: 1155: 1152: 1151: 1141: 1140: 1134: 1130: 1129: 1126: 1125: 1117: 1116: 1110: 1107: 1106: 1098: 1097: 1091: 1085: 1084: 1081: 1080: 1072: 1071: 1065: 1062: 1061: 1053: 1052: 1046: 1040: 1039: 1036: 1035: 1027: 1026: 1020: 1017: 1016: 1008: 1007: 1001: 995: 994: 989: 984: 980: 979: 969: 968: 965: 964: 953: 952: 950: 949: 944: 939: 934: 928: 926: 922: 921: 919: 918: 913: 908: 903: 897: 895: 891: 890: 888: 887: 882: 877: 872: 867: 862: 857: 851: 849: 845: 844: 834: 833: 830: 829: 826: 825: 817: 816: 805: 799: 798: 795: 794: 786: 785: 782: 781: 779: 778: 774: 770: 766: 762: 758: 754: 753:tail of embryo 750: 746: 742: 738: 735: 734: 723: 720: 719: 717: 716: 712: 708: 704: 703:body of uterus 700: 696: 692: 688: 684: 680: 676: 673: 672: 660: 659: 651: 640: 634: 633: 630:RNA expression 622: 621: 618: 617: 609: 605: 604: 596: 593: 588: 582: 581: 572: 565: 559: 555: 554: 549: 543: 542: 534: 533: 521: 520: 517: 516: 508: 504: 503: 495: 492: 487: 481: 480: 471: 464: 458: 454: 453: 446: 440: 439: 431: 430: 418: 417: 374: 370: 369: 361: 353: 352: 348: 347: 344: 343: 340: 339: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 3103: 3092: 3089: 3087: 3084: 3083: 3081: 3070: 3065: 3063: 3058: 3056: 3051: 3050: 3044: 3042: 3038: 3034: 3033:chromosome 19 3030: 3025: 3022: 3018: 3005: 3002: 3001: 2999: 2995: 2989: 2986: 2985: 2983: 2981: 2975: 2969: 2966: 2965: 2963: 2959: 2953: 2950: 2949: 2947: 2943: 2937: 2934: 2932: 2929: 2927: 2924: 2922: 2919: 2918: 2916: 2914: 2910: 2904: 2901: 2900: 2897: 2893: 2890: 2889: 2886: 2883: 2881: 2878: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2858: 2856: 2853: 2851: 2848: 2846: 2843: 2841: 2838: 2836: 2833: 2831: 2828: 2827: 2825: 2823: 2819: 2815: 2811: 2804: 2799: 2797: 2792: 2790: 2785: 2784: 2781: 2767: 2761: 2756: 2752: 2746: 2741: 2737: 2731: 2726: 2722: 2716: 2711: 2707: 2701: 2696: 2692: 2686: 2681: 2677: 2671: 2666: 2662: 2656: 2651: 2647: 2641: 2636: 2632: 2626: 2621: 2617: 2611: 2606: 2602: 2596: 2591: 2587: 2581: 2576: 2572: 2566: 2561: 2557: 2551: 2546: 2542: 2536: 2531: 2527: 2521: 2516: 2512: 2506: 2501: 2497: 2491: 2486: 2482: 2476: 2471: 2467: 2461: 2456: 2452: 2446: 2441: 2437: 2431: 2426: 2422: 2416: 2411: 2407: 2401: 2396: 2392: 2386: 2381: 2377: 2371: 2366: 2362: 2356: 2351: 2347: 2338: 2333: 2331: 2326: 2324: 2319: 2318: 2315: 2306: 2302: 2297: 2292: 2289:(6): 763–77. 2288: 2284: 2280: 2275: 2271: 2267: 2262: 2257: 2253: 2249: 2245: 2241: 2237: 2232: 2228: 2224: 2220: 2216: 2212: 2211:10.1038/74101 2208: 2205:(4): 329–35. 2204: 2200: 2194: 2190: 2186: 2181: 2176: 2172: 2168: 2164: 2160: 2156: 2151: 2147: 2143: 2138: 2133: 2129: 2125: 2121: 2117: 2113: 2108: 2104: 2100: 2095: 2090: 2086: 2082: 2078: 2074: 2070: 2065: 2061: 2057: 2053: 2049: 2045: 2044:10.1038/26912 2041: 2037: 2033: 2029: 2025: 2020: 2016: 2012: 2008: 2004: 2000: 1996: 1992: 1988: 1982: 1978: 1974: 1969: 1964: 1960: 1956: 1952: 1948: 1944: 1939: 1935: 1931: 1927: 1923: 1919: 1915: 1910: 1906: 1902: 1898: 1894: 1890: 1886: 1880: 1876: 1872: 1868: 1864: 1860: 1856: 1852: 1848: 1844: 1840: 1835: 1831: 1827: 1822: 1817: 1813: 1809: 1805: 1801: 1797: 1792: 1788: 1784: 1780: 1776: 1772: 1768: 1764: 1760: 1756: 1752: 1747: 1743: 1739: 1734: 1729: 1725: 1721: 1717: 1713: 1709: 1704: 1700: 1696: 1692: 1688: 1684: 1680: 1676: 1672: 1668: 1664: 1659: 1655: 1651: 1646: 1641: 1637: 1633: 1629: 1625: 1621: 1616: 1612: 1608: 1604: 1600: 1597:(2): 189–96. 1596: 1592: 1586: 1582: 1578: 1573: 1568: 1563: 1558: 1554: 1550: 1547:(6): 2495–9. 1546: 1542: 1538: 1533: 1532: 1527: 1518: 1514: 1509: 1504: 1500: 1496: 1492: 1488: 1484: 1477: 1474: 1469: 1463: 1460: 1455: 1451: 1447: 1443: 1440:(1–2): 15–9. 1439: 1435: 1427: 1424: 1419: 1415: 1409: 1406: 1401: 1397: 1391: 1388: 1384: 1380: 1375: 1373: 1371: 1367: 1363: 1359: 1354: 1352: 1350: 1346: 1339: 1337: 1335: 1331: 1323: 1321: 1319: 1316: 1312: 1308: 1296: 1291: 1287: 1283: 1280: 1276: 1269: 1267: 1264: 1260: 1256: 1252: 1249: 1245: 1241: 1234: 1232: 1228: 1224: 1218: 1214: 1211: 1205: 1203: 1197: 1193: 1190: 1186: 1179: 1177: 1173: 1169: 1163: 1159: 1156: 1150: 1148: 1142: 1138: 1135: 1133:RefSeq (mRNA) 1131: 1124: 1123: 1118: 1114: 1111: 1105: 1104: 1099: 1095: 1092: 1090: 1086: 1079: 1078: 1073: 1069: 1066: 1060: 1059: 1054: 1050: 1047: 1045: 1041: 1034: 1033: 1028: 1024: 1021: 1015: 1014: 1009: 1005: 1002: 1000: 996: 993: 990: 988: 985: 981: 978: 974: 970: 963: 959: 954: 948: 945: 943: 940: 938: 935: 933: 930: 929: 927: 924: 923: 917: 914: 912: 909: 907: 904: 902: 899: 898: 896: 893: 892: 886: 883: 881: 878: 876: 873: 871: 868: 866: 863: 861: 858: 856: 853: 852: 850: 847: 846: 843: 842:Gene ontology 839: 835: 823: 818: 814: 809: 806: 804: 800: 792: 787: 777:mesencephalon 776: 772: 768: 764: 760: 756: 752: 748: 744: 740: 739: 736: 732: 727: 724: 714: 710: 706: 702: 698: 694: 690: 686: 682: 678: 677: 674: 670: 665: 662: 661: 658: 656: 652: 650: 649: 645: 644: 641: 639: 635: 631: 627: 623: 615: 610: 606: 602: 597: 587: 583: 576: 569: 563: 556: 548: 544: 540: 535: 531: 526: 522: 514: 509: 505: 501: 496: 486: 482: 475: 468: 462: 455: 451: 445: 441: 437: 432: 428: 423: 419: 415: 411: 407: 403: 399: 395: 391: 387: 383: 379: 371: 366: 359: 354: 349: 338: 336: 332: 328: 324: 320: 316: 312: 308: 304: 300: 296: 292: 288: 284: 280: 276: 272: 268: 264: 260: 256: 252: 248: 244: 240: 236: 232: 228: 224: 220: 216: 212: 208: 204: 200: 196: 192: 188: 184: 180: 176: 172: 168: 164: 160: 156: 152: 148: 144: 140: 136: 132: 128: 124: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 3041:expanding it 3026: 2829: 2765: 2750: 2735: 2720: 2705: 2690: 2675: 2660: 2645: 2630: 2615: 2600: 2585: 2570: 2555: 2540: 2525: 2510: 2495: 2480: 2465: 2450: 2435: 2420: 2405: 2390: 2375: 2360: 2286: 2282: 2243: 2239: 2202: 2198: 2162: 2158: 2119: 2115: 2076: 2072: 2027: 2023: 1999:10.1038/1700 1993:(1): 46–50. 1990: 1986: 1950: 1946: 1917: 1914:Biochemistry 1913: 1888: 1884: 1842: 1838: 1803: 1799: 1754: 1750: 1715: 1711: 1666: 1662: 1627: 1623: 1594: 1590: 1544: 1540: 1490: 1486: 1476: 1462: 1437: 1433: 1426: 1417: 1408: 1399: 1390: 1327: 1324:Interactions 1314: 1306: 1305: 1227:NP_001272754 1223:NP_001040102 1220: 1199: 1172:NM_001285825 1168:NM_001046637 1165: 1144: 1120: 1101: 1075: 1056: 1030: 1011: 991: 986: 942:RNA splicing 653: 646: 373:External IDs 72: 2961:Translation 2343:PDB gallery 911:nucleoplasm 870:RNA binding 757:neural tube 699:right ovary 612:26,895,696 599:26,886,430 591:7|7 A3 511:40,765,389 498:40,750,637 351:Identifiers 3080:Categories 2952:Telomerase 1385:, May 2017 1364:, May 2017 1340:References 687:left ovary 657:(ortholog) 394:HomoloGene 3031:on human 2980:particles 1231:NP_056597 1202:NP_004587 1176:NM_015782 1147:NM_004596 977:Orthologs 402:GeneCards 2968:Ribosome 2903:SNRNP200 2305:11420046 2283:Immunity 2270:11101529 2227:13432764 2219:10742179 2189:10688667 2146:10648562 1517:11101529 1381:– 1360:– 1330:interact 1279:Wikidata 956:Sources: 916:U1 snRNP 745:yolk sac 741:epiblast 2137:2174293 2103:9848648 2094:1369720 2060:4359811 2052:9783582 2032:Bibcode 2007:9731529 1977:9312034 1968:1170207 1934:9265619 1905:8609632 1875:4265453 1867:8602269 1847:Bibcode 1830:8070414 1787:9404488 1779:7984237 1759:Bibcode 1742:2962859 1699:4336326 1691:2147232 1671:Bibcode 1654:1833186 1611:1831431 1581:1826055 1549:Bibcode 1454:1701111 1383:Ensembl 1362:Ensembl 1311:protein 1089:UniProt 1044:Ensembl 983:Species 962:QuickGO 906:nucleus 632:pattern 490:19q13.2 390:1855690 358:Aliases 2303:  2268:  2261:305846 2258:  2225:  2217:  2187:  2180:110837 2177:  2144:  2134:  2101:  2091:  2058:  2050:  2024:Nature 2015:585778 2013:  2005:  1975:  1965:  1932:  1903:  1873:  1865:  1839:Nature 1828:  1821:395300 1818:  1785:  1777:  1751:Nature 1740:  1733:553857 1730:  1697:  1689:  1663:Nature 1652:  1645:453073 1642:  1609:  1579:  1569:  1515:  1508:305846 1505:  1452:  1265:search 1263:PubMed 1122:Q62189 1103:P09012 999:Entrez 803:BioGPS 773:embryo 769:embryo 382:182285 3035:is a 2997:Other 2913:hnRNP 2822:snRNP 2223:S2CID 2056:S2CID 2011:S2CID 1871:S2CID 1783:S2CID 1695:S2CID 1572:51259 1334:CDC5L 1332:with 1315:SNRPA 1309:is a 1032:53607 992:Mouse 987:Human 958:Amigo 655:Mouse 648:Human 595:Start 530:Mouse 494:Start 427:Human 406:SNRPA 365:SNRPA 22:SNRPA 3037:stub 3029:gene 2766:2u1a 2751:2oj3 2736:2oih 2721:2nz4 2706:1zzn 2691:1vc7 2676:1vc6 2661:1vc5 2646:1vc0 2631:1vbz 2616:1vby 2601:1vbx 2586:1urn 2571:1u6b 2556:1sjf 2541:1sj4 2526:1sj3 2511:1oia 2496:1nu4 2481:1m5v 2466:1m5p 2451:1m5o 2436:1m5k 2421:1fht 2406:1dz5 2391:1drz 2376:1cx0 2361:1aud 2301:PMID 2266:PMID 2215:PMID 2185:PMID 2142:PMID 2099:PMID 2048:PMID 2003:PMID 1973:PMID 1930:PMID 1901:PMID 1863:PMID 1826:PMID 1775:PMID 1738:PMID 1687:PMID 1650:PMID 1607:PMID 1591:Gene 1577:PMID 1513:PMID 1450:PMID 1318:gene 1013:6626 638:Bgee 586:Band 547:Chr. 485:Band 444:Chr. 398:3380 378:OMIM 335:5FJ4 331:5DDP 327:5DDQ 323:5DDR 319:5DDO 315:4YB1 311:4W90 307:4PRF 303:4PR6 299:4C4W 295:3UD4 291:3UD3 287:3UCZ 283:3UCU 279:3R1L 275:3R1H 271:3PGW 267:3P49 263:3MXH 259:3MUV 255:3MUT 251:3MUR 247:3MUM 243:3L3C 239:3K0J 235:3IWN 231:3IRW 227:3IIN 223:3HHN 219:3G9C 215:3G96 211:3G8T 207:3G8S 203:3EGZ 199:3CUN 195:3CUL 191:3BO4 187:3BO3 183:3BO2 179:2U1A 175:2OJ3 171:2OIH 167:2NZ4 163:2A3J 159:1ZZN 155:1VC6 151:1VC5 147:1VC0 143:1VBZ 139:1VBY 135:1VBX 131:1URN 127:1U6B 123:1SJF 119:1SJ4 115:1SJ3 111:1OIA 107:1NU4 103:1M5V 99:1M5P 95:1M5O 91:1M5K 87:1FHT 83:1DZ5 79:1DRZ 75:1AUD 56:RCSB 53:PDBe 2892:70K 2291:doi 2256:PMC 2248:doi 2207:doi 2175:PMC 2167:doi 2132:PMC 2124:doi 2120:148 2089:PMC 2081:doi 2073:RNA 2040:doi 2028:395 1995:doi 1963:PMC 1955:doi 1922:doi 1893:doi 1889:257 1855:doi 1843:380 1816:PMC 1808:doi 1767:doi 1755:372 1728:PMC 1720:doi 1679:doi 1667:348 1640:PMC 1632:doi 1599:doi 1595:102 1567:PMC 1557:doi 1503:PMC 1495:doi 1442:doi 608:End 507:End 410:OMA 386:MGI 46:PDB 3082:: 2921:A0 2865:D3 2860:D2 2855:D1 2845:B2 2835:A1 2812:: 2299:. 2287:14 2285:. 2281:. 2264:. 2254:. 2244:19 2242:. 2238:. 2221:. 2213:. 2201:. 2183:. 2173:. 2163:20 2161:. 2157:. 2140:. 2130:. 2118:. 2114:. 2097:. 2087:. 2075:. 2071:. 2054:. 2046:. 2038:. 2026:. 2009:. 2001:. 1991:20 1989:. 1971:. 1961:. 1951:16 1949:. 1945:. 1928:. 1918:36 1916:. 1899:. 1887:. 1869:. 1861:. 1853:. 1841:. 1824:. 1814:. 1804:13 1802:. 1798:. 1781:. 1773:. 1765:. 1753:. 1736:. 1726:. 1714:. 1710:. 1693:. 1685:. 1677:. 1665:. 1648:. 1638:. 1628:10 1626:. 1622:. 1605:. 1593:. 1575:. 1565:. 1555:. 1545:88 1543:. 1539:. 1511:. 1501:. 1491:19 1489:. 1485:. 1448:. 1438:54 1436:. 1416:. 1398:. 1369:^ 1348:^ 1336:. 1320:. 960:/ 614:bp 601:bp 513:bp 500:bp 408:; 404:: 400:; 396:: 392:; 388:: 384:; 380:: 333:, 329:, 325:, 321:, 317:, 313:, 309:, 305:, 301:, 297:, 293:, 289:, 285:, 281:, 277:, 273:, 269:, 265:, 261:, 257:, 253:, 249:, 245:, 241:, 237:, 233:, 229:, 225:, 221:, 217:, 213:, 209:, 205:, 201:, 197:, 193:, 189:, 185:, 181:, 177:, 173:, 169:, 165:, 161:, 157:, 153:, 149:, 145:, 141:, 137:, 133:, 129:, 125:, 121:, 117:, 113:, 109:, 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 3068:e 3061:t 3054:v 3043:. 2936:R 2931:L 2926:C 2894:/ 2885:N 2880:G 2875:F 2870:E 2850:C 2840:B 2830:A 2802:e 2795:t 2788:v 2336:e 2329:t 2322:v 2307:. 2293:: 2272:. 2250:: 2229:. 2209:: 2203:7 2191:. 2169:: 2148:. 2126:: 2105:. 2083:: 2077:4 2062:. 2042:: 2034:: 2017:. 1997:: 1979:. 1957:: 1936:. 1924:: 1907:. 1895:: 1877:. 1857:: 1849:: 1832:. 1810:: 1789:. 1769:: 1761:: 1744:. 1722:: 1716:6 1701:. 1681:: 1673:: 1656:. 1634:: 1613:. 1601:: 1583:. 1559:: 1551:: 1519:. 1497:: 1470:. 1456:. 1444:: 1420:. 1402:. 532:) 429:) 412::

Index


PDB
PDBe
RCSB
1AUD
1DRZ
1DZ5
1FHT
1M5K
1M5O
1M5P
1M5V
1NU4
1OIA
1SJ3
1SJ4
1SJF
1U6B
1URN
1VBX
1VBY
1VBZ
1VC0
1VC5
1VC6
1ZZN
2A3J
2NZ4
2OIH
2OJ3

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