Knowledge (XXG)

Sodium/bile acid cotransporter

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to possible additional (non-HBV) aspects of NTCP-deficiency. NTCP-deficient mice are partially protected against the problems associated with a high-calorie diet, including excessive weight gain and to liver damage in cholestasis. These effects of NTCP deficiency have not yet been replicated in humans.
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Individuals that lack functional NTCP have been identified. These individuals display highly elevated bile salt levels in plasma, but without a clear phenotype. In areas of the world with a high prevalence of HBV, there are multiple individuals who carry the NTCP p.S267F polymorphism on both alleles;
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NTCP-deficient mice have also been created. These mice have reduced hepatic bile salt uptake but plasma bile salt levels are less clearly elevated, as the rodent-specific OATP1a/1b transporters provide can partially replace the function of NTCP. Nevertheless, this NTCP-knockout animal model pointed
2058:"The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism" 1781:
Shiao T, Iwahashi M, Fortune J, Quattrochi L, Bowman S, Wick M, et al. (October 2000). "Structural and functional characterization of liver cell-specific activity of the human sodium/taurocholate cotransporter".
1061:. Two homologous transporters are involved in the reabsorption of bile acids. One of these absorbs bile acids from the intestinal lumen, the bile duct, and the kidney with an apical localization ( 1918:
Jung D, Hagenbuch B, Fried M, Meier PJ, Kullak-Ublick GA (May 2004). "Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene".
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Chen HL, Chen HL, Liu YJ, Feng CH, Wu CY, Shyu MK, et al. (September 2005). "Developmental expression of canalicular transporter genes in human liver".
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Peng L, Zhao Q, Li Q, Li M, Li C, Xu T, et al. (April 2015). "The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B".
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Alrefai WA, Sarwar Z, Tyagi S, Saksena S, Dudeja PK, Gill RK (May 2005). "Cholesterol modulates human intestinal sodium-dependent bile acid transporter".
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Hallén S, Mareninova O, Brändén M, Sachs G (June 2002). "Organization of the membrane domain of the human liver sodium/bile acid cotransporter".
3449: 1595:"Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice" 5320: 5310: 4979: 4505: 1253: 1235: 4837: 2705: 2374: 2141: 1460:"The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro" 241: 5284: 3847: 3341: 2267: 2262: 2187: 2156: 927: 934: 218: 5233: 5134: 4301: 3263: 2561: 2475: 2232: 2091:
Dias V, Ribeiro V (August 2007). "The expression of the solute carriers NTCP and OCT-1 is regulated by cholesterol in HepG2 cells".
1511:"Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: conjugated hypercholanemia without a clear clinical phenotype" 3065: 1271: 5325: 3326: 2402: 2247: 1222: 1201: 5174: 2801: 5315: 5277: 5154: 5149: 5120: 3661: 3225: 3027: 3022: 2149: 140: 115: 1218: 1287:"Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter" 3220: 3215: 3210: 3195: 3190: 3185: 3180: 2970: 4546: 4348: 4148: 1197: 5144: 57: 3136: 254: 153: 4116: 3995: 3699: 247: 146: 4068: 2571: 2180: 1050: 4725: 4381: 2874: 1744:
Trauner M, Boyer JL (April 2003). "Bile salt transporters: molecular characterization, function, and regulation".
5129: 3017: 1054: 4913: 5179: 3001: 2768: 1137: 756: 65: 4870: 3397: 5139: 4771: 2500: 1693:"Na -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice" 737: 1394:"Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus" 1691:
Slijepcevic D, Roscam Abbing RL, Fuchs CD, Haazen LC, Beuers U, Trauner M, et al. (September 2018).
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Anwer MS, Gillin H, Mukhopadhyay S, Balasubramaniyan N, Suchy FJ, Ananthanarayanan M (September 2005).
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Donkers JM, Kooijman S, Slijepcevic D, Kunst RF, Roscam Abbing RL, Haazen L, et al. (June 2019).
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this makes NTCP inactive as a bile acid transporter, but provides protection against HBV infection.
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are integral membrane glycoproteins. Human NTCP contains 349 amino acids and has a mass of 56 kDa.
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Slijepcevic D, Kaufman C, Wichers CG, Gilglioni EH, Lempp FA, Duijst S, et al. (July 2015).
1575: 1272:"Entrez Gene: SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1" 89: 906: 881: 851: 826: 4707: 4702: 4050: 4045: 3972: 3967: 3962: 3957: 3952: 3947: 3927: 3922: 3917: 3912: 3897: 3887: 3877: 3872: 3862: 3837: 3643: 3628: 3623: 3245: 3240: 3235: 2108: 2079: 2044: 2009: 1972: 1935: 1906: 1871: 1842: 1799: 1761: 1722: 1673: 1624: 1567: 1532: 1491: 1425: 1374: 1316: 1105: 1101: 492: 37: 5261: 4961: 4928: 4895: 4885: 4852: 4847: 4781: 4662: 4614: 4604: 4561: 4525: 4520: 4487: 4482: 4477: 4472: 4463: 4458: 4453: 4425: 4415: 4406: 4401: 4396: 4231: 4216: 4211: 4196: 4163: 4130: 4040: 4000: 3757: 3729: 3714: 3709: 3704: 3681: 3676: 3524: 3520: 3511: 3469: 3293: 3283: 3273: 3205: 3151: 3085: 3070: 2904: 2899: 2894: 2745: 2646: 2641: 2611: 2535: 2530: 2525: 2452: 85: 5257: 5249: 5007: 3108: 2846: 2836: 2821: 2783: 2778: 2596: 2520: 2447: 2172: 2100: 2069: 2034: 2001: 1964: 1927: 1896: 1863: 1832: 1824: 1791: 1753: 1712: 1704: 1663: 1655: 1614: 1606: 1559: 1522: 1481: 1471: 1415: 1405: 1364: 1354: 1306: 1298: 334: 265: 209: 164: 5091: 2176: 1085: 1081: 309: 1509:
Vaz FM, Paulusma CC, Huidekoper H, de Ru M, Lim C, Koster J, et al. (January 2015).
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Gad SA, Sugiyama M, Tsuge M, Wakae K, Fukano K, Oshima M, et al. (March 2022).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1121: 1109: 1000: 997: 2005: 1757: 1659: 410: 5166: 4324: 1133: 1089: 226: 123: 73: 1968: 1931: 5103: 2023:"Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp" 1129: 1073: 1058: 1011: 656: 470: 348: 293: 280: 192: 179: 81: 2112: 2083: 2048: 2039: 2022: 2013: 1976: 1939: 1910: 1901: 1884: 1875: 1846: 1803: 1795: 1765: 1726: 1677: 1628: 1571: 1536: 1495: 1429: 1378: 1320: 974: 969: 4697: 4692: 4687: 4619: 4236: 3977: 3942: 3937: 3932: 3907: 3902: 3892: 3882: 3867: 3857: 3852: 3842: 3832: 3827: 3817: 3807: 3802: 3797: 3638: 3633: 3618: 3613: 3608: 3603: 3598: 3593: 3363: 3230: 2557: 2074: 2057: 1359: 1125: 958: 801: 782: 1410: 1392:
Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, et al. (November 2012).
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MĂĽller O, Schalla C, Scheibner J, Stange EF, Fuchs M (February 2002).
1708: 1644:"NTCP deficiency in mice protects against obesity and hepatosteatosis" 1610: 1563: 1527: 1510: 1302: 5188: 4277: 3812: 3359: 2841: 2831: 2826: 2816: 2811: 2806: 2773: 2730: 2725: 2720: 2715: 2697: 2692: 2687: 2682: 2606: 2601: 2591: 2586: 2553: 2515: 2505: 2495: 2490: 2480: 2442: 2437: 2432: 2427: 2422: 2417: 2412: 2407: 2384: 2379: 2330: 2320: 2315: 2257: 2252: 2242: 2237: 1957:
American Journal of Physiology. Gastrointestinal and Liver Physiology
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American Journal of Physiology. Gastrointestinal and Liver Physiology
1343:"NTCP and beyond: opening the door to unveil hepatitis B virus entry" 990: 942: 678: 1072:
As a cotransporter, NTCP binds two sodium ions and one (conjugated)
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H. Spreitzer (14 September 2015). "Neue Wirkstoffe – Myrcludex B".
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System A & N, sodium-coupled neutral amino-acid transporter
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Ho RH, Leake BF, Roberts RL, Lee W, Kim RB (February 2004).
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NTCP is a cell surface receptor necessary for the entry of
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high affinity glutamate and neutral amino-acid transporter
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influx of bile salts. Other transported molecules include
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cationic amino-acid transporter/glycoprotein-associated
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glycoprotein-associated/light or catalytic subunits of
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Eloranta JJ, Jung D, Kullak-Ublick GA (January 2006).
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Na-independent, system-L like amino-acid transporter
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Watashi K, Urban S, Li W, Wakita T (February 2014).
5165: 5102: 5000: 4972: 4944: 4906: 4863: 4830: 4797: 4764: 4718: 4630: 4577: 4539: 4498: 4374: 4341: 4317: 4294: 4270: 4179: 4141: 4109: 4061: 3988: 3740: 3692: 3654: 3536: 3442: 3390: 3352: 3319: 3256: 3167: 3129: 3101: 3058: 2994: 2963: 2867: 2794: 2761: 2672: 2546: 2468: 2395: 2366: 2278: 2225: 895: 874: 840: 819: 1214: 1212: 1210: 1193: 1191: 1189: 264: 163: 48:, NTCP, solute carrier family 10 member 1, FHCA2 1219:GRCm38: Ensembl release 89: ENSMUSG00000021135 5285: 2157: 1336: 1334: 1332: 1330: 8: 535:bile acid transmembrane transporter activity 3544:organic cation/anion/zwitterion transporter 1347:International Journal of Molecular Sciences 1198:GRCh38: Ensembl release 89: ENSG00000100652 5292: 5278: 5099: 5086: 5025: 4761: 4750: 4267: 4256: 3439: 3428: 3066:human Na-sulfate/carboxylate cotransporter 2960: 2949: 2222: 2211: 2207: 2196: 2164: 2150: 2142: 2132:United States National Library of Medicine 652: 517: 305: 204: 101: 2073: 2038: 1900: 1836: 1716: 1667: 1618: 1526: 1485: 1475: 1419: 1409: 1368: 1358: 1310: 2130:This article incorporates text from the 3662:Na+-dependent ascorbic acid transporter 2093:Fundamental & Clinical Pharmacology 1185: 1108:. This entry mechanism is inhibited by 3450:Organic anion-transporting polypeptide 18: 4506:proton-coupled amino-acid transporter 2706:heterodimeric amino-acid transporters 2375:heterodimeric amino-acid transporters 1291:The Journal of Clinical Investigation 581:integral component of plasma membrane 269: 230: 225: 168: 127: 122: 7: 5246: 5244: 2971:proton coupled metal ion transporter 1285:Hagenbuch B, Meier PJ (March 1994). 1063:ileal sodium/bile acid cotransporter 1026:(solute carrier family 10 member 1) 4547:sugar-phosphate/phosphate exchanger 4149:facilitative nucleoside transporter 2027:The Journal of Biological Chemistry 1889:The Journal of Biological Chemistry 550:bile acid:sodium symporter activity 5264:. You can help Knowledge (XXG) by 4349:type II Na-phosphate cotransporter 2562:sodium:neurotransmitter symporters 892: 871: 837: 816: 792: 773: 747: 728: 702: 683: 487: 405: 343: 322: 14: 4302:Vesicular glutamate transporter 1 3264:Vesicular glutamate transporter 1 3137:proton oligopeptide cotransporter 1022:that in humans is encoded by the 627:bile acid and bile salt transport 5248: 2105:10.1111/j.1472-8206.2007.00517.x 1445:Ă–sterreichische Apothekerzeitung 491: 253: 246: 240: 217: 152: 145: 139: 114: 4117:Na-coupled nucleoside transport 3996:multifunctional anion exchanger 3327:vesicular monoamine transporter 1076:molecule, thereby providing a 987:Sodium/bile acid cotransporter 566:integral component of membrane 502:More reference expression data 471:More reference expression data 1: 4980:multidrug and toxin extrusion 4069:fatty acid transport proteins 2286:facilitative GLUT transporter 238: 137: 5321:Thyroid hormone transporters 5311:Genes on human chromosome 14 4726:basolateral iron transporter 4382:nucleoside-sugar transporter 2875:sodium bile salt cotransport 2476:sodium glucose cotransporter 1477:10.1371/journal.ppat.1009983 2181:membrane transport proteins 1051:Bile acid:sodium symporters 576:basolateral plasma membrane 5342: 5243: 4914:Putative sugar transporter 2006:10.1016/j.jhep.2005.02.030 1758:10.1152/physrev.00027.2002 1660:10.1172/jci.insight.127197 1447:(in German) (19/2015): 12. 607:viral entry into host cell 429:sexually immature organism 5229: 5098: 5085: 5035: 5024: 4760: 4749: 4266: 4255: 3438: 3427: 2959: 2948: 2221: 2210: 2206: 2195: 1829:10.1042/0264-6021:3610673 1254:"Mouse PubMed Reference:" 1236:"Human PubMed Reference:" 1055:enterohepatic circulation 973: 968: 964: 957: 941: 922: 899: 878: 867: 844: 823: 812: 799: 795: 780: 776: 767: 754: 750: 735: 731: 722: 709: 705: 690: 686: 677: 662: 655: 651: 635: 520: 516: 499: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 5234:solute carrier disorders 4871:Choline-like transporter 3002:electroneutral cation-Cl 1969:10.1152/ajpgi.00379.2004 1932:10.1152/ajpgi.00456.2003 379:internal globus pallidus 4772:Magnesium transporter E 2403:bicarbonate transporter 2062:Molecular Endocrinology 1817:The Biochemical Journal 1069:of hepatocytes (NTCP). 928:Chr 14: 69.78 – 69.8 Mb 622:transmembrane transport 545:virus receptor activity 16:Protein found in humans 5326:Membrane protein stubs 5260:–related article is a 5167:Antiporter (exchanger) 2040:10.1074/jbc.M502151200 1902:10.1074/jbc.M305782200 1796:10.1006/geno.2000.6329 271:12 D1|12 37.21 cM 5316:Solute carrier family 4638:metal ion transporter 3748:mitochondrial carrier 3398:type III Na-phosphate 1994:Journal of Hepatology 1746:Physiological Reviews 1175:Solute carrier family 1146:tauroursodeoxycholate 1096:Hepatitis virus entry 1067:basolateral membranes 935:Chr 12: 81 – 81.02 Mb 232:Chromosome 12 (mouse) 130:Chromosome 14 (human) 2075:10.1210/me.2005-0159 1360:10.3390/ijms15022892 602:sodium ion transport 4805:Ammonia transporter 3700:Na/(Ca-K) exchanger 2033:(39): 33687–33692. 1411:10.7554/eLife.00049 1150:bromosulfophthalein 1053:participate in the 359:right lobe of liver 94:SLC10A1 - orthologs 4952:Folate transporter 2373:heavy subunits of 2134:, which is in the 1156:SLC10A1-deficiency 989:also known as the 757:ENSMUSG00000021135 595:Biological process 559:Cellular component 540:symporter activity 528:Molecular function 457:thoracic diaphragm 421:left lobe of liver 5273: 5272: 5241: 5240: 5225: 5224: 5221: 5220: 5081: 5080: 5077: 5076: 5073: 5072: 5020: 5019: 5016: 5015: 4745: 4744: 4741: 4740: 4251: 4250: 4247: 4246: 3423: 3422: 3419: 3418: 2944: 2943: 2940: 2939: 2173:Membrane proteins 1868:10.1021/bi012152s 1862:(23): 7253–7266. 1823:(Pt 3): 673–679. 1709:10.1002/hep.29888 1611:10.1002/hep.27694 1564:10.1002/hep.27608 1528:10.1002/hep.27240 1303:10.1172/JCI117091 1106:hepatitis D virus 1038:Sodium/bile acid 984: 983: 980: 979: 953: 952: 918: 917: 889: 888: 863: 862: 834: 833: 808: 807: 789: 788: 763: 762: 744: 743: 718: 717: 699: 698: 647: 646: 512: 511: 508: 507: 477: 476: 464: 463: 402: 401: 300: 299: 199: 198: 5333: 5294: 5287: 5280: 5258:membrane protein 5252: 5245: 5200: 5199: 5198: 5100: 5087: 5026: 5008:Heme transporter 4762: 4751: 4268: 4257: 3440: 3429: 3109:urea transporter 2961: 2950: 2223: 2212: 2208: 2197: 2177:carrier proteins 2166: 2159: 2152: 2143: 2124: 2087: 2077: 2052: 2042: 2017: 1988: 1963:(5): G978–G985. 1951: 1926:(5): G752–G761. 1914: 1904: 1895:(8): 7213–7222. 1879: 1850: 1840: 1807: 1777: 1731: 1730: 1720: 1703:(3): 1057–1069. 1688: 1682: 1681: 1671: 1639: 1633: 1632: 1622: 1590: 1584: 1583: 1558:(4): 1251–1260. 1547: 1541: 1540: 1530: 1506: 1500: 1499: 1489: 1479: 1455: 1449: 1448: 1440: 1434: 1433: 1423: 1413: 1389: 1383: 1382: 1372: 1362: 1353:(2): 2892–2905. 1338: 1325: 1324: 1314: 1297:(3): 1326–1331. 1282: 1276: 1275: 1268: 1262: 1261: 1250: 1244: 1243: 1232: 1226: 1216: 1205: 1195: 1136:as well as NTCP 1086:thyroid hormones 1082:steroid hormones 966: 965: 937: 930: 913: 893: 884: 872: 868:RefSeq (protein) 858: 838: 829: 817: 793: 774: 748: 729: 703: 684: 653: 518: 504: 495: 488: 473: 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 5341: 5340: 5336: 5335: 5334: 5332: 5331: 5330: 5301: 5300: 5299: 5298: 5242: 5237: 5217: 5197: 5194: 5193: 5192: 5190: 5161: 5124: 5094: 5069: 5031: 5012: 4996: 4968: 4940: 4902: 4859: 4826: 4793: 4756: 4737: 4714: 4626: 4573: 4535: 4494: 4370: 4337: 4313: 4290: 4262: 4243: 4175: 4137: 4105: 4057: 3984: 3736: 3688: 3650: 3532: 3434: 3415: 3386: 3348: 3315: 3252: 3175:monocarboxylate 3163: 3125: 3097: 3054: 2990: 2955: 2936: 2863: 2790: 2769:Na/Ca exchanger 2757: 2668: 2542: 2464: 2391: 2362: 2274: 2217: 2202: 2191: 2170: 2127: 2090: 2055: 2020: 1991: 1954: 1917: 1882: 1853: 1810: 1780: 1743: 1739: 1737:Further reading 1734: 1690: 1689: 1685: 1641: 1640: 1636: 1592: 1591: 1587: 1549: 1548: 1544: 1508: 1507: 1503: 1470:(3): e1009983. 1457: 1456: 1452: 1442: 1441: 1437: 1391: 1390: 1386: 1340: 1339: 1328: 1284: 1283: 1279: 1270: 1269: 1265: 1252: 1251: 1247: 1234: 1233: 1229: 1217: 1208: 1196: 1187: 1183: 1171: 1158: 1098: 1048: 1036: 975:View/Edit Mouse 970:View/Edit Human 933: 926: 923:Location (UCSC) 909: 905: 901: 880: 854: 850: 846: 825: 738:ENSG00000100652 631: 590: 571:plasma membrane 554: 500: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 387:muscle of thigh 385: 381: 377: 373: 371:Achilles tendon 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 5339: 5337: 5329: 5328: 5323: 5318: 5313: 5303: 5302: 5297: 5296: 5289: 5282: 5274: 5271: 5270: 5253: 5239: 5238: 5230: 5227: 5226: 5223: 5222: 5219: 5218: 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4625: 4624: 4623: 4622: 4617: 4612: 4607: 4602: 4597: 4592: 4581: 4579: 4575: 4574: 4572: 4571: 4570: 4569: 4564: 4559: 4554: 4543: 4541: 4537: 4536: 4534: 4533: 4532: 4531: 4523: 4518: 4513: 4502: 4500: 4496: 4495: 4493: 4492: 4491: 4490: 4485: 4480: 4475: 4468: 4467: 4466: 4461: 4456: 4449: 4448: 4447: 4442: 4435: 4434: 4433: 4428: 4423: 4418: 4411: 4410: 4409: 4404: 4399: 4394: 4389: 4378: 4376: 4372: 4371: 4369: 4368: 4367: 4366: 4361: 4356: 4345: 4343: 4339: 4338: 4336: 4335: 4334: 4333: 4321: 4319: 4315: 4314: 4312: 4311: 4310: 4309: 4298: 4296: 4292: 4291: 4289: 4288: 4287: 4286: 4274: 4272: 4264: 4263: 4260: 4253: 4252: 4249: 4248: 4245: 4244: 4242: 4241: 4240: 4239: 4234: 4229: 4224: 4219: 4214: 4209: 4204: 4199: 4194: 4183: 4181: 4177: 4176: 4174: 4173: 4172: 4171: 4166: 4161: 4156: 4145: 4143: 4139: 4138: 4136: 4135: 4134: 4133: 4128: 4113: 4111: 4107: 4106: 4104: 4103: 4102: 4101: 4096: 4091: 4086: 4081: 4076: 4065: 4063: 4059: 4058: 4056: 4055: 4054: 4053: 4048: 4043: 4038: 4033: 4028: 4023: 4018: 4013: 4008: 4003: 3992: 3990: 3986: 3985: 3983: 3982: 3981: 3980: 3975: 3970: 3965: 3960: 3955: 3950: 3945: 3940: 3935: 3930: 3925: 3920: 3915: 3910: 3905: 3900: 3895: 3890: 3885: 3880: 3875: 3870: 3865: 3860: 3855: 3850: 3845: 3840: 3835: 3830: 3825: 3820: 3815: 3810: 3805: 3800: 3795: 3790: 3785: 3780: 3775: 3770: 3765: 3760: 3755: 3744: 3742: 3738: 3737: 3735: 3734: 3733: 3732: 3727: 3722: 3717: 3712: 3707: 3696: 3694: 3690: 3689: 3687: 3686: 3685: 3684: 3679: 3674: 3669: 3658: 3656: 3652: 3651: 3649: 3648: 3647: 3646: 3641: 3636: 3631: 3626: 3621: 3616: 3611: 3606: 3601: 3596: 3591: 3586: 3581: 3576: 3571: 3566: 3561: 3556: 3551: 3540: 3538: 3534: 3533: 3531: 3530: 3529: 3528: 3516: 3515: 3514: 3509: 3502: 3501: 3500: 3493: 3492: 3491: 3486: 3479: 3478: 3477: 3472: 3467: 3462: 3457: 3446: 3444: 3436: 3435: 3432: 3425: 3424: 3421: 3420: 3417: 3416: 3414: 3413: 3412: 3411: 3406: 3400:cotransporter 3394: 3392: 3388: 3387: 3385: 3384: 3383: 3382: 3377: 3372: 3356: 3354: 3350: 3349: 3347: 3346: 3345: 3344: 3339: 3334: 3323: 3321: 3317: 3316: 3314: 3313: 3312: 3311: 3306: 3301: 3296: 3291: 3286: 3281: 3276: 3271: 3260: 3258: 3254: 3253: 3251: 3250: 3249: 3248: 3243: 3238: 3233: 3228: 3223: 3218: 3213: 3208: 3203: 3198: 3193: 3188: 3183: 3171: 3169: 3165: 3164: 3162: 3161: 3160: 3159: 3154: 3149: 3144: 3133: 3131: 3127: 3126: 3124: 3123: 3122: 3121: 3116: 3105: 3103: 3099: 3098: 3096: 3095: 3094: 3093: 3088: 3083: 3078: 3073: 3062: 3060: 3056: 3055: 3053: 3052: 3051: 3050: 3045: 3040: 3035: 3030: 3025: 3020: 3015: 3010: 3004:cotransporter 2998: 2996: 2992: 2991: 2989: 2988: 2987: 2986: 2978: 2967: 2965: 2957: 2956: 2953: 2946: 2945: 2942: 2941: 2938: 2937: 2935: 2934: 2929: 2924: 2919: 2914: 2913: 2912: 2907: 2902: 2897: 2892: 2887: 2882: 2871: 2869: 2865: 2864: 2862: 2861: 2860: 2859: 2854: 2849: 2844: 2839: 2834: 2829: 2824: 2819: 2814: 2809: 2802:Na/H exchanger 2798: 2796: 2792: 2791: 2789: 2788: 2787: 2786: 2781: 2776: 2765: 2763: 2759: 2758: 2756: 2755: 2754: 2753: 2748: 2743: 2738: 2733: 2728: 2723: 2718: 2713: 2702: 2701: 2700: 2695: 2690: 2685: 2676: 2674: 2670: 2669: 2667: 2666: 2665: 2664: 2659: 2654: 2649: 2644: 2639: 2634: 2629: 2624: 2619: 2614: 2609: 2604: 2599: 2594: 2589: 2584: 2579: 2574: 2569: 2550: 2548: 2544: 2543: 2541: 2540: 2539: 2538: 2533: 2528: 2523: 2518: 2513: 2508: 2503: 2498: 2493: 2488: 2483: 2472: 2470: 2466: 2465: 2463: 2462: 2461: 2460: 2455: 2450: 2445: 2440: 2435: 2430: 2425: 2420: 2415: 2410: 2399: 2397: 2393: 2392: 2390: 2389: 2388: 2387: 2382: 2370: 2368: 2364: 2363: 2361: 2360: 2359: 2358: 2353: 2348: 2343: 2338: 2333: 2328: 2323: 2318: 2313: 2308: 2303: 2298: 2293: 2282: 2280: 2276: 2275: 2273: 2272: 2271: 2270: 2265: 2260: 2255: 2250: 2245: 2240: 2229: 2227: 2219: 2218: 2215: 2204: 2203: 2200: 2193: 2192: 2184:solute carrier 2171: 2169: 2168: 2161: 2154: 2146: 2126: 2125: 2099:(4): 445–450. 2088: 2053: 2018: 2000:(3): 472–477. 1989: 1952: 1915: 1880: 1851: 1808: 1790:(2): 203–213. 1778: 1752:(2): 633–671. 1740: 1738: 1735: 1733: 1732: 1683: 1634: 1605:(1): 207–219. 1585: 1542: 1521:(1): 260–267. 1501: 1464:PLOS Pathogens 1450: 1435: 1384: 1326: 1277: 1263: 1245: 1227: 1206: 1184: 1182: 1179: 1178: 1177: 1170: 1167: 1157: 1154: 1097: 1094: 1047: 1044: 1040:cotransporters 1035: 1032: 998:cotransporting 982: 981: 978: 977: 972: 962: 961: 955: 954: 951: 950: 948: 946: 939: 938: 931: 924: 920: 919: 916: 915: 897: 896: 890: 887: 886: 876: 875: 869: 865: 864: 861: 860: 842: 841: 835: 832: 831: 821: 820: 814: 810: 809: 806: 805: 797: 796: 790: 787: 786: 778: 777: 771: 765: 764: 761: 760: 752: 751: 745: 742: 741: 733: 732: 726: 720: 719: 716: 715: 707: 706: 700: 697: 696: 688: 687: 681: 675: 674: 669: 664: 660: 659: 649: 648: 645: 644: 633: 632: 630: 629: 624: 619: 614: 609: 604: 598: 596: 592: 591: 589: 588: 583: 578: 573: 568: 562: 560: 556: 555: 553: 552: 547: 542: 537: 531: 529: 525: 524: 514: 513: 510: 509: 506: 505: 497: 496: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 5338: 5327: 5324: 5322: 5319: 5317: 5314: 5312: 5309: 5308: 5306: 5295: 5290: 5288: 5283: 5281: 5276: 5275: 5269: 5267: 5263: 5259: 5254: 5251: 5247: 5236: 5235: 5228: 5214: 5211: 5209: 5206: 5202: 5186: 5183: 5182: 5181: 5178: 5176: 5173: 5172: 5170: 5168: 5164: 5156: 5153: 5151: 5148: 5147: 5146: 5143: 5141: 5138: 5136: 5133: 5131: 5128: 5126: 5119: 5117: 5114: 5113: 5111: 5109: 5108:Cotransporter 5105: 5101: 5097: 5093: 5088: 5084: 5066: 5063: 5061: 5058: 5056: 5053: 5051: 5048: 5046: 5043: 5041: 5038: 5037: 5034: 5027: 5023: 5009: 5006: 5005: 5003: 4999: 4991: 4988: 4986: 4983: 4982: 4981: 4978: 4977: 4975: 4971: 4963: 4960: 4958: 4955: 4954: 4953: 4950: 4949: 4947: 4943: 4935: 4932: 4930: 4927: 4925: 4922: 4920: 4917: 4916: 4915: 4912: 4911: 4909: 4905: 4897: 4894: 4892: 4889: 4887: 4884: 4882: 4879: 4877: 4874: 4873: 4872: 4869: 4868: 4866: 4862: 4854: 4851: 4849: 4846: 4844: 4841: 4840: 4839: 4836: 4835: 4833: 4829: 4821: 4818: 4816: 4813: 4811: 4808: 4807: 4806: 4803: 4802: 4800: 4796: 4788: 4785: 4783: 4780: 4778: 4775: 4774: 4773: 4770: 4769: 4767: 4763: 4759: 4752: 4748: 4732: 4729: 4728: 4727: 4724: 4723: 4721: 4717: 4709: 4706: 4704: 4701: 4699: 4696: 4694: 4691: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4641: 4640: 4639: 4636: 4635: 4633: 4629: 4621: 4618: 4616: 4613: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4587: 4586: 4583: 4582: 4580: 4576: 4568: 4565: 4563: 4560: 4558: 4555: 4553: 4550: 4549: 4548: 4545: 4544: 4542: 4538: 4530: 4527: 4524: 4522: 4519: 4517: 4514: 4512: 4509: 4508: 4507: 4504: 4503: 4501: 4497: 4489: 4486: 4484: 4481: 4479: 4476: 4474: 4471: 4470: 4469: 4465: 4462: 4460: 4457: 4455: 4452: 4451: 4450: 4446: 4443: 4441: 4438: 4437: 4436: 4432: 4429: 4427: 4424: 4422: 4419: 4417: 4414: 4413: 4412: 4408: 4405: 4403: 4400: 4398: 4395: 4393: 4390: 4388: 4385: 4384: 4383: 4380: 4379: 4377: 4373: 4365: 4362: 4360: 4357: 4355: 4352: 4351: 4350: 4347: 4346: 4344: 4340: 4332: 4329: 4328: 4326: 4323: 4322: 4320: 4316: 4308: 4305: 4304: 4303: 4300: 4299: 4297: 4293: 4285: 4282: 4281: 4279: 4276: 4275: 4273: 4269: 4265: 4258: 4254: 4238: 4235: 4233: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4203: 4200: 4198: 4195: 4193: 4190: 4189: 4188: 4185: 4184: 4182: 4178: 4170: 4167: 4165: 4162: 4160: 4157: 4155: 4152: 4151: 4150: 4147: 4146: 4144: 4140: 4132: 4129: 4127: 4124: 4123: 4122: 4118: 4115: 4114: 4112: 4108: 4100: 4097: 4095: 4092: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4071: 4070: 4067: 4066: 4064: 4060: 4052: 4049: 4047: 4044: 4042: 4039: 4037: 4034: 4032: 4029: 4027: 4024: 4022: 4019: 4017: 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3998: 3997: 3994: 3993: 3991: 3987: 3979: 3976: 3974: 3971: 3969: 3966: 3964: 3961: 3959: 3956: 3954: 3951: 3949: 3946: 3944: 3941: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3919: 3916: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3894: 3891: 3889: 3886: 3884: 3881: 3879: 3876: 3874: 3871: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3750: 3749: 3746: 3745: 3743: 3739: 3731: 3728: 3726: 3723: 3721: 3718: 3716: 3713: 3711: 3708: 3706: 3703: 3702: 3701: 3698: 3697: 3695: 3691: 3683: 3680: 3678: 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2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2288: 2287: 2284: 2283: 2281: 2277: 2269: 2266: 2264: 2261: 2259: 2256: 2254: 2251: 2249: 2246: 2244: 2241: 2239: 2236: 2235: 2234: 2231: 2230: 2228: 2224: 2220: 2213: 2209: 2205: 2198: 2194: 2189: 2185: 2182: 2178: 2174: 2167: 2162: 2160: 2155: 2153: 2148: 2147: 2144: 2140: 2139: 2137: 2136:public domain 2133: 2122: 2118: 2114: 2110: 2106: 2102: 2098: 2094: 2089: 2085: 2081: 2076: 2071: 2067: 2063: 2059: 2054: 2050: 2046: 2041: 2036: 2032: 2028: 2024: 2019: 2015: 2011: 2007: 2003: 1999: 1995: 1990: 1986: 1982: 1978: 1974: 1970: 1966: 1962: 1958: 1953: 1949: 1945: 1941: 1937: 1933: 1929: 1925: 1921: 1916: 1912: 1908: 1903: 1898: 1894: 1890: 1886: 1881: 1877: 1873: 1869: 1865: 1861: 1857: 1852: 1848: 1844: 1839: 1834: 1830: 1826: 1822: 1818: 1814: 1809: 1805: 1801: 1797: 1793: 1789: 1785: 1779: 1775: 1771: 1767: 1763: 1759: 1755: 1751: 1747: 1742: 1741: 1736: 1728: 1724: 1719: 1714: 1710: 1706: 1702: 1698: 1694: 1687: 1684: 1679: 1675: 1670: 1665: 1661: 1657: 1653: 1649: 1645: 1638: 1635: 1630: 1626: 1621: 1616: 1612: 1608: 1604: 1600: 1596: 1589: 1586: 1581: 1577: 1573: 1569: 1565: 1561: 1557: 1553: 1546: 1543: 1538: 1534: 1529: 1524: 1520: 1516: 1512: 1505: 1502: 1497: 1493: 1488: 1483: 1478: 1473: 1469: 1465: 1461: 1454: 1451: 1446: 1439: 1436: 1431: 1427: 1422: 1417: 1412: 1407: 1403: 1399: 1395: 1388: 1385: 1380: 1376: 1371: 1366: 1361: 1356: 1352: 1348: 1344: 1337: 1335: 1333: 1331: 1327: 1322: 1318: 1313: 1308: 1304: 1300: 1296: 1292: 1288: 1281: 1278: 1273: 1267: 1264: 1259: 1255: 1249: 1246: 1241: 1237: 1231: 1228: 1224: 1220: 1215: 1213: 1211: 1207: 1203: 1199: 1194: 1192: 1190: 1186: 1180: 1176: 1173: 1172: 1168: 1166: 1162: 1155: 1153: 1151: 1147: 1143: 1139: 1135: 1131: 1127: 1123: 1119: 1115: 1114:cyclosporin A 1111: 1107: 1103: 1095: 1093: 1091: 1087: 1083: 1079: 1075: 1070: 1068: 1064: 1060: 1056: 1052: 1045: 1043: 1041: 1033: 1031: 1029: 1025: 1021: 1017: 1014:transporter ( 1013: 1010: 1006: 1002: 999: 996: 992: 988: 976: 971: 967: 963: 960: 956: 949: 947: 944: 940: 936: 932: 929: 925: 921: 914: 912: 908: 904: 898: 894: 891: 885: 883: 877: 873: 870: 866: 859: 857: 853: 849: 843: 839: 836: 830: 828: 822: 818: 815: 813:RefSeq (mRNA) 811: 804: 803: 798: 794: 791: 785: 784: 779: 775: 772: 770: 766: 759: 758: 753: 749: 746: 740: 739: 734: 730: 727: 725: 721: 714: 713: 708: 704: 701: 695: 694: 689: 685: 682: 680: 676: 673: 670: 668: 665: 661: 658: 654: 650: 643: 639: 634: 628: 625: 623: 620: 618: 617:ion transport 615: 613: 612:viral process 610: 608: 605: 603: 600: 599: 597: 594: 593: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 563: 561: 558: 557: 551: 548: 546: 543: 541: 538: 536: 533: 532: 530: 527: 526: 523: 522:Gene ontology 519: 515: 503: 498: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 5266:expanding it 5255: 5231: 4327:transporter 4280:transporter 3366:transporter 3177:transporter 2560:- dependent 2129: 2128: 2096: 2092: 2068:(1): 65–79. 2065: 2061: 2030: 2026: 1997: 1993: 1960: 1956: 1923: 1919: 1892: 1888: 1859: 1856:Biochemistry 1855: 1820: 1816: 1787: 1783: 1749: 1745: 1700: 1696: 1686: 1651: 1647: 1637: 1602: 1598: 1588: 1555: 1551: 1545: 1518: 1514: 1504: 1467: 1463: 1453: 1444: 1438: 1401: 1397: 1387: 1350: 1346: 1294: 1290: 1280: 1266: 1257: 1248: 1239: 1230: 1163: 1159: 1142:taurocholate 1118:progesterone 1099: 1088:and various 1071: 1049: 1037: 1023: 1015: 1004: 995:taurocholate 986: 985: 911:NP_001348901 903:NP_001171032 900: 879: 856:NM_001361972 848:NM_001177561 845: 824: 800: 781: 755: 736: 710: 691: 671: 666: 333: 326: 53:External IDs 4187:zinc efflux 1648:JCI Insight 1122:propranolol 1110:myrcludex B 1102:hepatitis B 1090:xenobiotics 1001:polypeptide 437:granulocyte 425:gallbladder 383:gallbladder 375:granulocyte 367:sural nerve 292:81,015,479 279:80,999,957 191:69,797,241 178:69,775,416 31:Identifiers 5305:Categories 5213:Cl-oxalate 5208:Cl-formate 5135:Na/glucose 4325:Acetyl-CoA 1697:Hepatology 1599:Hepatology 1552:Hepatology 1515:Hepatology 1404:: e00049. 1225:, May 2017 1204:, May 2017 1181:References 1138:substrates 1134:bexarotene 1059:bile acids 445:blastocyst 337:(ortholog) 74:HomoloGene 5232:see also 5104:Symporter 5092:Ion pumps 1580:205895418 1130:ezetimibe 1074:bile salt 1034:Structure 1012:bile acid 907:NP_035517 882:NP_003040 852:NM_011387 827:NM_003049 657:Orthologs 82:GeneCards 5201:(Band 3) 5185:Na/(Ca-K 4755:SLC41–48 4708:SLC39A14 4703:SLC39A13 4698:SLC39A12 4693:SLC39A11 4688:SLC39A10 4620:SLC38A10 4261:SLC31–40 4237:SLC30A10 4051:SLC26A11 4046:SLC26A10 3978:SLC25A46 3973:SLC25A45 3968:SLC25A44 3963:SLC25A43 3958:SLC25A42 3953:SLC25A41 3948:SLC25A40 3943:SLC25A39 3938:SLC25A38 3933:SLC25A37 3928:SLC25A36 3923:SLC25A35 3918:SLC25A34 3913:SLC25A33 3908:SLC25A32 3903:SLC25A31 3898:SLC25A30 3893:SLC25A29 3888:SLC25A28 3883:SLC25A27 3878:SLC25A26 3873:SLC25A25 3868:SLC25A24 3863:SLC25A23 3858:SLC25A22 3853:SLC25A21 3848:SLC25A20 3843:SLC25A19 3838:SLC25A18 3833:SLC25A17 3828:SLC25A16 3823:SLC25A15 3818:SLC25A14 3813:SLC25A13 3808:SLC25A12 3803:SLC25A11 3798:SLC25A10 3644:SLC22A20 3639:SLC22A19 3634:SLC22A18 3629:SLC22A17 3624:SLC22A16 3619:SLC22A15 3614:SLC22A14 3609:SLC22A13 3604:SLC22A12 3599:SLC22A11 3594:SLC22A10 3433:SLC21–30 3364:thiamine 3246:SLC16A14 3241:SLC16A13 3236:SLC16A12 3231:SLC16A11 3226:SLC16A10 2954:SLC11–20 2558:chloride 2201:By group 2121:46522965 2113:17635184 2084:16123152 2049:16027164 2014:15922475 1977:15604201 1940:14701722 1911:14660639 1876:12044156 1847:11802798 1804:11031103 1784:Genomics 1766:12663868 1727:29572910 1678:31237863 1629:25641256 1572:25418280 1537:24867799 1496:35312737 1430:23150796 1379:24557582 1221:– 1200:– 1169:See also 1126:bosentan 1046:Function 959:Wikidata 636:Sources: 586:membrane 363:testicle 5116:Na/K,Cl 5030:SLCO1–4 4990:SLC47A2 4985:SLC47A1 4962:SLC46A2 4957:SLC46A1 4934:SLC45A4 4929:SLC54A3 4924:SLC45A2 4919:SLC45A1 4896:SLC44A5 4891:SLC44A4 4886:SLC44A3 4881:SLC44A2 4876:SLC44A1 4853:SLC43A3 4848:SLC43A2 4843:SLC43A1 4787:SLC41A3 4782:SLC41A2 4777:SLC41A1 4731:SLC40A1 4683:SLC39A9 4678:SLC39A8 4673:SLC39A7 4668:SLC39A6 4663:SLC39A5 4658:SLC39A4 4653:SLC39A3 4648:SLC39A2 4643:SLC39A1 4615:SLC38A6 4610:SLC38A5 4605:SLC38A4 4600:SLC38A3 4595:SLC38A2 4590:SLC38A1 4567:SLC37A4 4562:SLC37A3 4557:SLC37A2 4552:SLC37A1 4526:SLC36A4 4521:SLC36A3 4516:SLC36A2 4511:SLC36A1 4488:SLC35E4 4483:SLC35E3 4478:SLC35E2 4473:SLC35E1 4464:SLC35D3 4459:SLC35D2 4454:SLC35D1 4445:SLC35C2 4440:SLC35C1 4431:SLC35B4 4426:SLC35B3 4421:SLC35B2 4416:SLC35B1 4407:SLC35A5 4402:SLC35A4 4397:SLC35A3 4392:SLC35A2 4387:SLC35A1 4364:SLC34A3 4359:SLC34A2 4354:SLC34A1 4331:SLC33A1 4307:SLC32A1 4284:SLC31A1 4232:SLC30A9 4227:SLC30A8 4222:SLC30A7 4217:SLC30A6 4212:SLC30A5 4207:SLC30A4 4202:SLC30A3 4197:SLC30A2 4192:SLC30A1 4169:SLC29A4 4164:SLC29A3 4159:SLC29A2 4154:SLC29A1 4131:SLC28A3 4126:SLC28A2 4121:SLC28A1 4099:SLC27A6 4094:SLC27A5 4089:SLC27A4 4084:SLC27A3 4079:SLC27A2 4074:SLC27A1 4041:SLC26A9 4036:SLC26A8 4031:SLC26A7 4026:SLC26A6 4021:SLC26A5 4016:SLC26A4 4011:SLC26A3 4006:SLC26A2 4001:SLC26A1 3793:SLC25A9 3788:SLC25A8 3783:SLC25A7 3778:SLC25A6 3773:SLC25A5 3768:SLC25A4 3763:SLC25A3 3758:SLC25A2 3753:SLC25A1 3730:SLC24A6 3725:SLC24A5 3720:SLC24A4 3715:SLC24A3 3710:SLC24A2 3705:SLC24A1 3682:SLC23A4 3677:SLC23A3 3672:SLC23A2 3667:SLC23A1 3589:SLC22A9 3584:SLC22A8 3579:SLC22A7 3574:SLC22A6 3569:SLC22A5 3564:SLC22A4 3559:SLC22A3 3554:SLC22A2 3549:SLC22A1 3525:SLCO6A1 3521:SLCO5A1 3512:SLCO4C1 3507:SLCO4A1 3498:SLCO3A1 3489:SLCO2B1 3484:SLCO2A1 3475:SLCO1C1 3470:SLCO1B4 3465:SLCO1B3 3460:SLCO1B1 3455:SLCO1A2 3409:SLC20A2 3404:SLC20A1 3380:SLC19A3 3375:SLC19A2 3370:SLC19A1 3342:SLC18A3 3337:SLC18A2 3332:SLC18A1 3309:SLC17A9 3304:SLC17A8 3299:SLC17A7 3294:SLC17A6 3289:SLC17A5 3284:SLC17A4 3279:SLC17A3 3274:SLC17A2 3269:SLC17A1 3221:SLC16A9 3216:SLC16A8 3211:SLC16A7 3206:SLC16A6 3201:SLC16A5 3196:SLC16A4 3191:SLC16A3 3186:SLC16A2 3181:SLC16A1 3157:SLC15A4 3152:SLC15A3 3147:SLC15A2 3142:SLC15A1 3119:SLC14A2 3114:SLC14A1 3091:SLC13A5 3086:SLC13A4 3081:SLC13A3 3076:SLC13A2 3071:SLC13A1 3048:SLC12A9 3043:SLC12A8 3038:SLC12A7 3033:SLC12A6 3028:SLC12A5 3023:SLC12A4 3018:SLC12A3 3013:SLC12A2 3008:SLC12A1 2981:SLC11A2 2976:SLC11A1 2910:SLC10A7 2905:SLC10A6 2900:SLC10A5 2895:SLC10A4 2890:SLC10A3 2885:SLC10A2 2880:SLC10A1 2857:SLC9A11 2852:SLC9A10 2751:SLC7A14 2746:SLC7A13 2741:SLC7A11 2736:SLC7A10 2662:SLC6A20 2657:SLC6A19 2652:SLC6A18 2647:SLC6A17 2642:SLC6A16 2637:SLC6A15 2632:SLC6A14 2627:SLC6A13 2622:SLC6A12 2617:SLC6A11 2612:SLC6A10 2216:SLC1–10 1948:1101720 1838:1222351 1774:5911966 1718:6175374 1669:6675549 1620:4657468 1487:8970526 1421:3485615 1370:3958888 1321:8132774 1223:Ensembl 1202:Ensembl 1078:hepatic 1024:SLC10A1 1020:protein 1018:) is a 769:UniProt 724:Ensembl 663:Species 642:QuickGO 312:pattern 170:14q24.1 86:SLC10A1 45:SLC10A1 38:Aliases 22:SLC10A1 4278:copper 3360:folate 2847:SLC9A9 2842:SLC9A8 2837:SLC9A7 2832:SLC9A6 2827:SLC9A5 2822:SLC9A4 2817:SLC9A3 2812:SLC9A2 2807:SLC9A1 2784:SLC8A3 2779:SLC8A2 2774:SLC8A1 2731:SLC7A9 2726:SLC7A8 2721:SLC7A7 2716:SLC7A6 2711:SLC7A5 2698:SLC7A4 2693:SLC7A3 2688:SLC7A2 2683:SLC7A1 2607:SLC6A9 2602:SLC6A8 2597:SLC6A7 2592:SLC6A6 2587:SLC6A5 2582:SLC6A4 2577:SLC6A3 2572:SLC6A2 2567:SLC6A1 2556:- and 2554:sodium 2481:SLC5A1 2408:SLC4A1 2380:SLC3A1 2291:SLC2A1 2238:SLC1A1 2119:  2111:  2082:  2047:  2012:  1985:633434 1983:  1975:  1946:  1938:  1909:  1874:  1845:  1835:  1802:  1772:  1764:  1725:  1715:  1676:  1666:  1654:(14). 1627:  1617:  1578:  1570:  1535:  1494:  1484:  1428:  1418:  1377:  1367:  1319:  1312:294097 1309:  945:search 943:PubMed 802:O08705 783:Q14973 679:Entrez 483:BioGPS 453:morula 449:morula 441:zygote 433:embryo 391:kidney 62:182396 5256:This 5180:Na/Ca 5130:Na/Cl 5001:(48): 4973:(47): 4945:(46): 4907:(45): 4864:(44): 4831:(43): 4798:(42): 4765:(41): 4719:(40): 4631:(39): 4578:(38): 4540:(37): 4499:(36): 4375:(35): 4342:(34): 4318:(33): 4295:(32): 4271:(31): 4180:(30): 4142:(29): 4110:(28): 4062:(27): 3989:(26): 3741:(25): 3693:(24): 3655:(23): 3537:(22): 3443:(21): 3391:(20): 3353:(19): 3320:(18): 3257:(17): 3168:(16): 3130:(15): 3102:(14): 3059:(13): 2995:(12): 2964:(11): 2868:(10): 2188:TC 2A 2117:S2CID 1981:S2CID 1944:S2CID 1770:S2CID 1576:S2CID 1398:eLife 1140:like 1009:liver 1007:) or 712:20493 672:Mouse 667:Human 638:Amigo 395:blood 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:31126 70:97379 5262:stub 5187:) - 5175:Na/H 5145:Cl/K 5140:Na/I 5121:Na/P 5065:O4A1 5060:O431 5055:O2B1 5050:O1B3 5045:O1B1 5040:O1A2 4820:RhCG 4815:RhBG 4810:RhAG 4529:36A2 2984:11A3 2932:10A7 2927:10A3 2922:10A2 2917:10A1 2795:(9): 2762:(8): 2673:(7): 2547:(6): 2469:(5): 2396:(4): 2367:(3): 2279:(2): 2226:(1): 2109:PMID 2080:PMID 2045:PMID 2010:PMID 1973:PMID 1936:PMID 1907:PMID 1872:PMID 1843:PMID 1800:PMID 1762:PMID 1723:PMID 1674:PMID 1625:PMID 1568:PMID 1533:PMID 1492:PMID 1426:PMID 1375:PMID 1317:PMID 1148:and 1104:and 1028:gene 1016:LBAT 1005:NTCP 693:6554 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 5191:HCO 5189:Cl/ 2101:doi 2070:doi 2035:doi 2031:280 2002:doi 1965:doi 1961:288 1928:doi 1924:286 1897:doi 1893:279 1864:doi 1833:PMC 1825:doi 1821:361 1792:doi 1754:doi 1713:PMC 1705:doi 1664:PMC 1656:doi 1615:PMC 1607:doi 1560:doi 1523:doi 1482:PMC 1472:doi 1416:PMC 1406:doi 1365:PMC 1355:doi 1307:PMC 1299:doi 1057:of 288:End 187:End 90:OMA 66:MGI 5307:: 5106:, 2536:12 2531:11 2526:10 2458:11 2453:10 2356:14 2351:13 2346:12 2341:11 2336:10 2179:: 2175:, 2115:. 2107:. 2097:21 2095:. 2078:. 2066:20 2064:. 2060:. 2043:. 2029:. 2025:. 2008:. 1998:43 1996:. 1979:. 1971:. 1959:. 1942:. 1934:. 1922:. 1905:. 1891:. 1887:. 1870:. 1860:41 1858:. 1841:. 1831:. 1819:. 1815:. 1798:. 1788:69 1786:. 1768:. 1760:. 1750:83 1748:. 1721:. 1711:. 1701:68 1699:. 1695:. 1672:. 1662:. 1650:. 1646:. 1623:. 1613:. 1603:62 1601:. 1597:. 1574:. 1566:. 1556:61 1554:. 1531:. 1519:61 1517:. 1513:. 1490:. 1480:. 1468:18 1466:. 1462:. 1424:. 1414:. 1400:. 1396:. 1373:. 1363:. 1351:15 1349:. 1345:. 1329:^ 1315:. 1305:. 1295:93 1293:. 1289:. 1256:. 1238:. 1209:^ 1188:^ 1152:. 1144:, 1132:, 1128:, 1124:, 1120:, 1116:, 1112:, 1092:: 1084:, 1030:. 991:Na 640:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 5293:e 5286:t 5279:v 5268:. 5196:3 5155:5 5150:4 5125:3 5123:i 4119:( 3527:) 3523:( 3362:/ 2521:9 2516:8 2511:7 2506:6 2501:5 2496:4 2491:3 2486:2 2448:9 2443:8 2438:7 2433:6 2428:5 2423:4 2418:3 2413:2 2385:2 2331:9 2326:8 2321:7 2316:6 2311:5 2306:4 2301:3 2296:2 2268:7 2263:6 2258:5 2253:4 2248:3 2243:2 2190:) 2186:( 2165:e 2158:t 2151:v 2138:. 2123:. 2103:: 2086:. 2072:: 2051:. 2037:: 2016:. 2004:: 1987:. 1967:: 1950:. 1930:: 1913:. 1899:: 1878:. 1866:: 1849:. 1827:: 1806:. 1794:: 1776:. 1756:: 1729:. 1707:: 1680:. 1658:: 1652:5 1631:. 1609:: 1582:. 1562:: 1539:. 1525:: 1498:. 1474:: 1432:. 1408:: 1402:1 1381:. 1357:: 1323:. 1301:: 1274:. 1260:. 1242:. 1003:( 993:- 212:) 109:) 92::

Index

Aliases
SLC10A1
OMIM
182396
MGI
97379
HomoloGene
31126
GeneCards
SLC10A1
OMA
SLC10A1 - orthologs
Human
Chromosome 14 (human)
Chr.
Chromosome 14 (human)
Chromosome 14 (human)
Genomic location for SLC10A1
Genomic location for SLC10A1
Band
bp
bp
Mouse
Chromosome 12 (mouse)
Chr.
Chromosome 12 (mouse)
Genomic location for SLC10A1
Genomic location for SLC10A1
Band
bp

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