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and was initially interested in biology, but found the courses uninspiring and instead chose to focus on math and physics. During his undergraduate work he took a leave of absence to work in a biology laboratory, where he studied the genetics of
328:, becoming a professor of human genetics and development as well as the directory of the Institute of Cancer Research. He was particularly interested in potential viral causes of cancer. In 1975, he was named University Professor.
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in response to environmental factors. He continued to work at
Washington University until 1948, and then took a one-year
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two years later, and received his PhD from that institution in 1944. His graduate work focused on what was then known as
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Gillespie D; Spiegelman S (July 1965). "A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane".
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Rich A; Davies DR (1956). "A new, 2-stranded helical structure, polyadenylic acid and polyuridylic acid".
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building on work by Rich and Davies in 1956, which helped to lay the groundwork for advances in
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297:. His work with Qβ RNA led to a noted experiment with self reproducing RNA structures called
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in
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487:"DR. SOL SPIEGELMAN, MICROBIOLOGIST AT COLUMBIA AND GENETICIST, DIES"
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associated with nucleic acid synthesis, originating from work on
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Recipients of the Albert Lasker Award for Basic
Medical Research
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Spiegelman and his wife Helen had three children. He died of
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in 1974 for his 1965 work on Qβ RNA. In 1981 he received the
249:"induction" or "adaptation", now known to reflect changes in
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Members of the United States
National Academy of Sciences
188:(December 14, 1914 – January 21, 1983) was an American
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Columbia
University College of Physicians and Surgeons
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in mathematics. He then began his graduate studies at
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Fellows of the
American Academy of Arts and Sciences
604:- Profiles in Science, National Library of Medicine
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420:"The Sol Spiegelman Papers: Biographical Overview"
426:. US National Library of Medicine. March 12, 2019
678:Washington University School of Medicine alumni
301:. Among his best-known work is his research on
269:In 1949, Spiegelman joined the faculty at the
241:. Spiegelman joined Steinbach in his move to
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305:, much of which was conducted in along with
598:- National Library of Medicine finding aid
346:United States National Academy of Sciences
160:University of Illinois at Urbana-Champaign
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243:Washington University School of Medicine
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342:Antonio Feltrinelli International prize
320:Spiegelman's later research focused on
683:Deaths from cancer in New York (state)
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350:American Academy of Arts and Sciences
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485:Webster, Bayard (January 22, 1983).
512:Kornberg, Hans (October 22, 1992).
114:Washington University in St. Louis
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596:Sol Spiegelman Papers (1929-1983)
514:"Obituary: Kimball C. Atwood III"
192:. He developed the technique of
673:20th-century American biologists
653:Scientists from New York (state)
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668:City College of New York alumni
457:. National Academy of Sciences
225:. He graduated in 1939 with a
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628:American molecular biologists
572:10.1016/S0022-2836(65)80331-X
324:and in 1969 he moved to the
16:American molecular biologist
643:Columbia University faculty
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638:Jewish American scientists
303:nucleic acid hybridization
194:nucleic acid hybridization
124:nucleic acid hybridization
602:The Sol Spiegelman Papers
237:under the supervision of
216:in 1914. He attended the
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633:Scientists from Brooklyn
336:Spiegelman received the
277:and particularly on the
218:City College of New York
204:Early life and education
110:City College of New York
259:University of Minnesota
208:Spiegelman was born in
271:University of Illinois
255:Public Health Service
299:Spiegelman's Monster
128:Spiegelman's monster
545:10.1021/ja01595a086
424:Profiles in Science
235:cellular physiology
231:Columbia University
190:molecular biologist
164:Columbia University
491:The New York Times
374:Spiegelman Monster
257:fellowship at the
233:in 1940, studying
362:pancreatic cancer
332:Awards and honors
311:Ferruccio Ritossa
227:bachelor's degree
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170:Doctoral students
146:Molecular biology
136:Scientific career
53:December 14, 1914
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455:Member Directory
451:"Sol Spiegelman"
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295:bacteriophage Qβ
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75:January 21, 1983
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106:Alma mater
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539:(14): 3548–9.
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338:Lasker Award
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156:Institutions
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77:(1983-01-21)
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623:1983 deaths
618:1914 births
497:January 18,
461:January 18,
430:January 18,
287:RNA genomes
98:Nationality
612:Categories
560:J Mol Biol
380:References
307:Kim Atwood
130:experiment
49:1914-12-14
364:in 1983.
291:MS2 phage
247:enzymatic
368:See also
348:in 1965
289:such as
223:bacteria
210:Brooklyn
150:genetics
101:American
87:New York
83:New York
61:New York
57:Brooklyn
580:4955314
279:enzymes
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322:cancer
142:Fields
285:with
576:PMID
499:2021
463:2021
432:2021
309:and
293:and
91:U.S.
72:Died
65:U.S.
43:Born
568:doi
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
