Knowledge (XXG)

Sudan IV

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While the dye does stain triglycerides with an intense red color, it does not stain lipid droplets or phospholipids. Sudan IV can be used to stain the aorta by staining lipid-rich plaques. The dye can also be used to stain lipids in atherosclerotic lesions in mice.
630:, or 0.05% by weight in acetone:ethanol:water (50:35:15). The idea is to use a moderately apolar solvent to solubilize the dye allowing it to partition into the highly apolar fat without the solvent solubilizing the fat to be stained. 440: 412: 618:. Staining is an important biochemical technique, offering the ability to visually qualify the presence of the fatty compound of interest without isolating it. For staining purposes, Sudan IV can be made up in 490: 537: 63:
Sudan R, C.I. Solvent Red 24, C.I. 26105, Lipid Crimson, Oil Red, Oil Red BB, Fat Red B, Oil Red IV, Scarlet Red, Scarlet Red N.F, Scarlet Red Scharlach, Scarlet R
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InChI=1S/C24H20N4O/c1-16-7-3-6-10-21(16)26-25-19-12-13-22(17(2)15-19)27-28-24-20-9-5-4-8-18(20)11-14-23(24)29/h3-15,29H,1-2H3/b26-25+,28-27+
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InChI=1S/C24H20N4O/c1-16-7-3-6-10-21(16)26-25-19-12-13-22(17(2)15-19)27-28-24-20-9-5-4-8-18(20)11-14-23(24)29/h3-15,29H,1-2H3/b26-25+,28-27+
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sections. It has the appearance of reddish brown crystals with melting point 199 Â°C and maximum absorption at 520(357) nm.
959: 482: 1051: 544: 472: 262: 1188: 283: 1218: 1092: 709:, Sudan IV is considered an illegal dye, mainly because of its harmful effect over a long period of time, as it is a 431: 199: 1238: 1101: 1026: 502: 758:
Refat NA, Ibrahim ZS, Moustafa GG, et al. (2008). "The induction of cytochrome P450 1A1 by sudan dyes".
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Except where otherwise noted, data are given for materials in their
34: 226: 896: 713:. It was ruled unsafe in the 1995 food safety regulations report. 622:. Alternatively, authors have reported using the dye saturated in 120: 108: 98: 874: 217: 839: 671: 667: 663: 288: 662:
In industry, it is used to color nonpolar substances like
532: 655:, which should not be confused with the water-soluble 1254: 1139: 1079: 991: 968: 940: 895: 873: 640:, and Sudan IV have been classified as category 3 250: 369:Cc4ccccc4/N=N/c3ccc(/N=N/c1c2ccccc2ccc1O)c(C)c3 84: 851: 8: 646:International Agency for Research on Cancer 858: 844: 836: 303: 190: 168: 26: 270: 726: 366: 324: 299: 61:1-{2-Methyl-4-phenyl}azonaphthalen-2-ol 1157:Jaswant Singh–Bhattacharji (JSB) stain 701:; because of that it is also known as 181: 602:Sudan IV is one of the dyes used for 348:Key: RCTGMCJBQGBLKT-PAMTUDGESA-N 331:Key: RCTGMCJBQGBLKT-PAMTUDGESA-N 148: 128: 7: 341:Key: RCTGMCJBQGBLKT-PAMTUDGEBE 241: 225: 1234:Grocott's methenamine silver stain 651:In its purified form it is called 25: 867:Microbial and histological stains 52:1-phenyl}diazenyl]naphthalen-2-ol 522: 430: 33: 518:(at 25 Â°C , 100 kPa). 1: 735:"Oil Red O Staining Protocol" 689:. Sudan IV is also used in 1334: 960:Periodic acid–Schiff stain 512: 411: 406: 377: 357: 315: 68: 58: 46: 41: 32: 1313:IARC Group 3 carcinogens 1102:Light Green SF yellowish 1093:Masson's trichrome stain 1052:Auramine–rhodamine stain 760:J. Biochem. Mol. Toxicol 473:Precautionary statements 606:. Similar dyes include 1219:Schaeffer–Fulton stain 1189:Gömöri trichrome stain 1194:Luxol fast blue stain 1069:Auramine phenol stain 1239:Warthin–Starry stain 1112:Phosphomolybdic acid 48:Preferred IUPAC name 1255:Tissue stainability 1027:Ziehl–Neelsen stain 887:Perls Prussian blue 697:to dye lower-taxed 29: 1229:Bielschowsky stain 1131:Van Gieson's stain 1097:Lillie's trichrome 653:Biebrich scarlet R 575:(fat-soluble dye) 545:Infobox references 27: 1280: 1279: 1081:Connective tissue 772:10.1002/jbt.20220 624:isopropyl alcohol 553:Chemical compound 551: 550: 455:Hazard statements 284:CompTox Dashboard 110:Interactive image 16:(Redirected from 1325: 1107:Biebrich scarlet 860: 853: 846: 837: 817: 816: 814: 812: 798: 792: 791: 755: 749: 748: 746: 745: 731: 657:Biebrich scarlet 620:propylene glycol 535: 529: 526: 525: 508: 504: 500: 496: 492: 488: 484: 480: 466: 462: 434: 385:Chemical formula 308: 307: 292: 290: 274: 254: 243: 229: 202: 194: 183: 172: 152: 132: 112: 88: 37: 30: 21: 1333: 1332: 1328: 1327: 1326: 1324: 1323: 1322: 1283: 1282: 1281: 1276: 1250: 1135: 1089:trichrome stain 1075: 987: 964: 936: 891: 869: 864: 826: 821: 820: 810: 808: 800: 799: 795: 757: 756: 752: 743: 741: 733: 732: 728: 723: 570: 566: 562: 554: 547: 542: 541: 540:  ?) 531: 527: 523: 519: 475: 457: 443: 427: 401: 397: 393: 387: 373: 370: 365: 364: 353: 350: 349: 343: 342: 339: 333: 332: 329: 323: 322: 311: 293: 286: 277: 257: 244: 232: 212: 175: 155: 135: 115: 102: 91: 78: 64: 62: 54: 53: 23: 22: 15: 12: 11: 5: 1331: 1329: 1321: 1320: 1315: 1310: 1305: 1300: 1295: 1285: 1284: 1278: 1277: 1275: 1274: 1269: 1264: 1258: 1256: 1252: 1251: 1249: 1248: 1246:Wright's stain 1243: 1242: 1241: 1236: 1231: 1221: 1216: 1211: 1206: 1201: 1196: 1191: 1186: 1181: 1176: 1175: 1174: 1169: 1159: 1154: 1149: 1143: 1141: 1137: 1136: 1134: 1133: 1127: 1126: 1125: 1124: 1119: 1117:Fast Green FCF 1114: 1109: 1104: 1085: 1083: 1077: 1076: 1074: 1073: 1072: 1071: 1066: 1065: 1064: 1059: 1049: 1048: 1047: 1045:Methylene blue 1042: 1036:Carbol fuchsin 1019: 1018: 1017: 1012: 1010:Gentian violet 997: 995: 989: 988: 986: 985: 980: 974: 972: 966: 965: 963: 962: 957: 952: 946: 944: 938: 937: 935: 934: 933: 932: 927: 922: 917: 912: 901: 899: 893: 892: 890: 889: 883: 881: 871: 870: 865: 863: 862: 855: 848: 840: 834: 833: 825: 824:External links 822: 819: 818: 806:MilliporeSigma 793: 750: 725: 724: 722: 719: 691:United Kingdom 682:products, and 604:Sudan staining 568: 564: 560: 552: 549: 548: 543: 521: 520: 516:standard state 513: 510: 509: 491:P305+P351+P338 476: 471: 468: 467: 458: 453: 450: 449: 444: 439: 436: 435: 428: 423: 420: 419: 409: 408: 404: 403: 399: 395: 391: 388: 383: 380: 379: 375: 374: 372: 371: 368: 360: 359: 358: 355: 354: 352: 351: 347: 346: 344: 340: 337: 336: 334: 330: 327: 326: 318: 317: 316: 313: 312: 310: 309: 296: 294: 282: 279: 278: 276: 275: 267: 265: 259: 258: 256: 255: 247: 245: 237: 234: 233: 231: 230: 222: 220: 214: 213: 211: 210: 206: 204: 196: 195: 185: 177: 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1031:Kinyoun stain 1028: 1025: 1024: 1023: 1020: 1016: 1013: 1011: 1007: 1006:Methyl violet 1004: 1003: 1002: 999: 998: 996: 994: 990: 984: 981: 979: 976: 975: 973: 971: 967: 961: 958: 956: 953: 951: 948: 947: 945: 943: 942:Carbohydrates 939: 931: 930:Sudan Black B 928: 926: 923: 921: 918: 916: 913: 911: 908: 907: 906: 903: 902: 900: 898: 894: 888: 885: 884: 882: 880: 876: 872: 868: 861: 856: 854: 849: 847: 842: 841: 838: 831: 828: 827: 823: 807: 803: 797: 794: 789: 785: 781: 777: 773: 769: 765: 761: 754: 751: 740: 736: 730: 727: 720: 718: 714: 712: 708: 704: 700: 696: 692: 688: 685: 681: 677: 673: 669: 665: 660: 658: 654: 649: 647: 643: 639: 635: 631: 629: 625: 621: 617: 616:Sudan Black B 613: 609: 605: 600: 598: 594: 590: 589:triglycerides 586: 582: 579:used for the 578: 574: 558: 546: 539: 534: 517: 511: 477: 474: 470: 469: 459: 456: 452: 451: 448: 445: 442: 438: 437: 433: 429: 426: 422: 421: 417: 415: 410: 405: 389: 386: 382: 381: 376: 367: 363: 356: 345: 335: 325: 321: 314: 306: 302: 301:DTXSID8041743 298: 297: 295: 285: 281: 280: 273: 269: 268: 266: 264: 261: 260: 253: 249: 248: 246: 240: 236: 235: 228: 224: 223: 221: 219: 216: 215: 208: 207: 205: 203: 198: 197: 193: 189: 186: 184: 182:ECHA InfoCard 179: 178: 171: 167: 166: 164: 162: 159: 158: 151: 150:ChEMBL1707454 147: 146: 144: 142: 139: 138: 131: 127: 126: 124: 122: 119: 118: 111: 107: 106: 104: 100: 95: 94: 87: 83: 82: 80: 77: 73: 72: 67: 57: 49: 45: 40: 36: 31: 19: 1272:Chromophobic 1224:Silver stain 1184:Giemsa stain 1167:Haematoxylin 919: 809:. Retrieved 805: 796: 766:(2): 77–84. 763: 759: 753: 742:. Retrieved 738: 729: 715: 702: 661: 652: 650: 632: 601: 593:lipoproteins 556: 555: 446: 413: 69:Identifiers 59:Other names 1318:2-Naphthols 1262:Acidophilic 1214:Neutral red 1199:Methyl blue 1062:Rhodamine B 955:Mucicarmine 950:Alcian blue 905:Sudan stain 879:hemosiderin 830:Stains File 811:15 February 703:Oil Tax Red 699:heating oil 680:hydrocarbon 441:Signal word 378:Properties 188:100.001.487 130:CHEBI:88014 1303:Sudan dyes 1287:Categories 1267:Basophilic 1122:Sirius Red 1057:Auramine O 1001:Gram stain 983:Thioflavin 802:"Sudan IV" 744:2021-03-17 721:References 711:carcinogen 678:, various 642:carcinogen 595:on frozen 573:lysochrome 425:Pictograms 272:I35E9QU96C 161:ChemSpider 97:3D model ( 76:CAS Number 1308:Fuel dyes 1022:Acid-fast 978:Congo red 925:Oil Red O 915:Sudan III 788:206010951 739:IHC World 687:emulsions 638:Sudan III 612:Sudan III 608:Oil Red O 577:diazo dye 503:P337+P313 499:P332+P313 487:P302+P352 416:labelling 209:201-635-8 201:EC Number 28:Sudan IV 1293:Azo dyes 1040:Fuchsine 1015:Safranin 993:Bacteria 920:Sudan IV 910:Sudan II 780:18418879 707:food dye 695:fuel dye 597:paraffin 581:staining 571:O) is a 557:Sudan IV 407:Hazards 402:O 170:11252033 1172:Eosin Y 1152:Cyanine 970:Amyloid 705:. As a 684:acrylic 676:greases 644:by the 634:Sudan I 628:ethanol 538:what is 536: ( 447:Warning 239:PubChem 86:85-83-6 897:Lipids 786:  778:  626:, 95% 614:, and 585:lipids 533:verify 530:  362:SMILES 227:C19520 141:ChEMBL 42:Names 1140:Other 832:entry 784:S2CID 693:as a 672:waxes 320:InChI 252:62330 121:ChEBI 99:JSmol 875:Iron 813:2023 776:PMID 668:fats 664:oils 591:and 507:P362 495:P321 483:P280 479:P264 465:H319 461:H315 263:UNII 218:KEGG 768:doi 583:of 414:GHS 289:EPA 242:CID 1289:: 1091:: 804:. 782:. 774:. 764:22 762:. 737:. 674:, 670:, 666:, 659:. 648:. 636:, 610:, 587:, 565:20 561:24 559:(C 505:, 501:, 497:, 493:, 489:, 485:, 481:, 463:, 418:: 396:20 392:24 1095:/ 1038:/ 1029:/ 1008:/ 877:/ 859:e 852:t 845:v 815:. 790:. 770:: 747:. 569:4 567:N 563:H 528:N 400:4 398:N 394:H 390:C 291:) 287:( 101:) 20:)

Index

Solvent Red 24

Preferred IUPAC name
CAS Number
85-83-6
JSmol
Interactive image
ChEBI
CHEBI:88014
ChEMBL
ChEMBL1707454
ChemSpider
11252033
ECHA InfoCard
100.001.487
Edit this at Wikidata
EC Number
KEGG
C19520
PubChem
62330
UNII
I35E9QU96C
CompTox Dashboard
DTXSID8041743
Edit this at Wikidata
InChI
SMILES
Chemical formula
GHS labelling

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