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Spasticity

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409:. Assessment is needed of the affected individual's goals, their function, and any symptoms that may be related to the movement disorder, such as pain. A thorough assessment will include analysis of posture, active movement, muscle strength, movement control and coordination, and endurance, as well as spasticity (response of the muscle to stretch). Spastic muscles typically demonstrate a loss of selective movement, including a loss of eccentric control (decreased ability to actively lengthen). While multiple muscles in a limb are usually affected in the upper motor neuron syndrome, there is usually an imbalance of activity, such that there is a stronger pull in one direction, such as into elbow flexion. Decreasing the degree of this imbalance is a common focus of muscle strengthening programs. Spastic movement disorders also typically feature a loss of 362:
compared to the non-spastic muscles in the same person's body (if any exist). Spasticity can be differentiated from rigidity with the help of simple clinical examination, as rigidity is a uniform increase in the tone of agonist and antagonist muscles which is not related to the velocity at which the movement is performed passively and remains the same throughout the range of movement while spasticity is a velocity-dependent increase in tone resulting from the hyperexcitability of stretch reflexes. It primarily involves the antigravity muscles – flexors of the upper limb and extensors of the lower limb. During the passive stretch, a brief "free interval" is appreciated in spasticity but not in rigidity because the resting muscle is electromyographically silent in spasticity. In contrast, in rigidity, the resting muscle shows firing.
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severity of the upper motor neuron damage. The result for the affected individual, is that they may have any degree of impairment, ranging from a mild to a severe movement disorder. A relatively mild movement disorder may contribute to a loss of dexterity in an arm, or difficulty with high level mobility such as running or walking on stairs. A severe movement disorder may result in marked loss of function with minimal or no volitional muscle activation. There are several scales used to measure spasticity, such as the King's hypertonicity scale, the Tardieu, and the
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spasticity is actually caused by an injury to a part of the central nervous system (the brain or spinal cord) that controls voluntary movements. The damage causes a change in the balance of signals between the nervous system and the muscles. This imbalance leads to increased activity (excitability) in the muscles. Receptors in the muscles receive messages from the nervous system, which sense the amount of stretch in the muscle and sends that signal to the brain. The brain responds by sending a message back to reverse the stretch by contracting or shortening.
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characteristic of spasticity, which may be referred to as "seatbelt effect" of spasticity, is different as the amount of resistance offered by the muscle is directly proportional to velocity of the passive movement. It is caused by increased muscle spindle excitability and velocity sensitivity of Ia spindle afferent nerve fibres, resulting in excessive activation of alpha motor neurons of the spinal cord. It is similar to the tug we feel initially while pulling the seatbelt of a car beyond a certain velocity, hence the name "seatbelt effect"
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severe gait difficulties. In the event of contracture there is no role for conservative treatment. Hip dislocation and ankle equinus deformity are known to arise from muscle spasticity primarily. Orthopedic surgical reconstruction of the hip is commonly practiced to improve sitting balance, nursing care and relieve hip pain. Treatment should be done with firm and constant manual contact positioned over nonspastic areas to avoid stimulating the spastic muscle(s). Alternatively,
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program). Most people with a significant UMN lesion will have ongoing impairment, but most of these will be able to make progress. The most important factor to indicate ability to progress is seeing improvement, but improvement in many spastic movement disorders may not be seen until the affected individual receives help from a specialised team or health professional.
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children is usually generalized although with varying degrees of severity across the affected extremities and trunk musculature. Neglected or inappropriately treated spasticity can eventually lead to joint contractures. Both spasticity and contractures can cause joint subluxations or dislocations and
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is the sudden decrease of tone after initial resistance, also referred to as a lengthening reaction or a "catch-yield sequence". This is because of inverse stretch reflex activation mediated by the Golgi tendon organ on sustained muscle stretching resulting in sudden relaxation of the muscle. Another
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positive cells, similar to stem cells, are extremely adaptable and, when extracted from a brain, cultured and then re-injected in a lesioned area of the same brain, they can help repair and rebuild it. The treatment using them would take some time to be available for general public use, as it has to
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The cause of spasticity is thought to be where an imbalance occurs in the excitatory and inhibitory input to α motor neurons caused by damage to the spinal cord and/or central nervous system. The damage causes a change in the balance of signals between the nervous system and the muscles, leading to
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in the treatment program may help decrease spasm severity, promote functional independence, improve motor recovery and decrease medication required for spasticity, which may help reduce the side effects that are possible with oral drug treatments. A 2004 study compared the effects of hydrotherapy
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Secondary effects are likely to impact on assessment of spastic muscles. If a muscle has impaired function following an upper motor neuron lesion, other changes such as increased muscle stiffness are likely to affect the feeling of resistance to passive stretch. Other secondary changes such as loss
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is caused by spasticity of the hip adductor muscles while tip-toeing gait is caused by spasticity of the gastrocnemius-soleus muscle complex or calf musculature. Also, following an upper motor neuron lesion, there may be multiple muscles affected, to varying degrees, depending on the location and
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The prognosis for those with spastic muscles depends on multiple factors, including the severity of the spasticity and the associated movement disorder, access to specialised and intensive management, and ability of the affected individual to maintain the management plan (particularly an exercise
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injections into the muscle belly, to attempt to dampen the signals between nerve and muscle. The effectiveness of medications vary between individuals, and vary based on location of the upper motor neuron lesion (in the brain or the spinal cord). Medications are commonly used for spastic movement
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Historical progression of spasticity and the upper motor neuron lesion on which it is based has progressed considerably in recent decades. However, the term "spasticity" is still often used interchangeably with "upper motor neuron syndrome" in the clinical settings, and it is not unusual to see
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should be the mainstay of management, and is likely needed to be prescribed by a physiatrist (a doctor specialized in rehabilitation medicine), occupational therapist, physical therapist, accredited exercise physiologist (AEP) or other health professional skilled in neurological rehabilitation.
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Spasticity is assessed by feeling the resistance of the muscle to passive lengthening in its most relaxed state. A spastic muscle will have immediately noticeable, often quite forceful, increased resistance to passive stretch when moved with speed and/or while attempting to be stretched out, as
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One factor that is thought to be related to spasticity is the stretch reflex. This reflex is important in coordinating normal movements in which muscles are contracted and relaxed and in keeping the muscle from stretching too far. Although the result of spasticity is problems with the muscles,
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Overall, a defining feature of spasticity is that the increased resistance to passive stretch is velocity-dependent. Lance (1980) describes it this way: "...a motor disorder, characterised by a velocity-dependent increase in tonic stretch reflexes (muscle tone) with exaggerated tendon jerks,
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likely due to their common physiological origins. Some consider clonus as simply an extended outcome of spasticity. Although closely linked, clonus is not seen in all patients with spasticity. Clonus tends to not be present with spasticity in patients with significantly increased
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for nerve signal conduction, and thus increases activity of structures innervated by the affected nerves (spasticity). Muscles affected in this way have many other potential features of altered performance in addition to spasticity, including muscle
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can be used to provide high volumes of passive or assisted movement, depending on the individual's requirements; this form of therapy can be useful if therapists are at a premium, and has been found effective at reducing spasticity in patients with
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Beresneva J, Stirane D, Kiukucane E, Vetra A (2009). "The use of aquatic therapy in stroke patients for the management of spasticity...Proceedings of the 10th Congress of the European Federation for Research in Rehabilitation, Riga, Latvia".
2076: 551:(SCI). It was found that subjects who received hydrotherapy treatment obtained increased FIM scores and a decreased intake of oral baclofen medication. A 2009 study looked at the effect of hydrotherapy to decrease spasticity on post- 701: 523:
disorders, but research has not shown functional benefit for some drugs. Some studies have shown that medications have been effective in decreasing spasticity, but that this has not been accompanied by functional benefits.
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of muscle fibres following acquired muscle weakness are likely to compound the weakness arising from the upper motor neuron lesion. In severely affected spastic muscles, there may be marked secondary changes, such as
3980: 4048: 3386: 369:, there are likely to be multiple other changes in affected musculature and surrounding bones, such as progressive malalignments of bone structure around the spastic muscles (leading for example to the 389:
Assessment of a movement disorder featuring spasticity may involve several health professionals depending on the affected individual's situation, and the severity of their condition. This may include
2176: 3772: 3767: 600:, but the evidence does not support these as effective. While splinting is not considered effective for decreasing spasticity, a range of different orthotics are effectively used for preventing 3784: 3762: 1400:
El-Sobky TA, Fayyad TA, Kotb AM, Kaldas B (May 2018). "Bony reconstruction of hip in cerebral palsy children Gross Motor Function Classification System levels III to V: a systematic review".
386:. Of these three, only the King's hypertonicity scale measures a range of muscle changes from the UMN lesion, including active muscle performance as well as passive response to stretch. 2935: 398: 173:
increased excitability in muscles. This is common in people who have cerebral palsy, brain injuries or a spinal cord injury, but it can happen to anybody e.g. having a stroke.
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patients with limited mobility and concluded that there was a significantly larger increase in FIM scores compared to the control group that did not receive hydrotherapy.
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Krebs HI, Palazzolo JJ, Dipietro L, Ferraro M, Krol J, Rannekleiv K, et al. (2003). "Rehabilitation robotics: Performance-based progressive robot-assisted therapy".
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spasticity. Also, from at least the 1950s through at least the 1980s, there was a strong focus on other interventions for spastic muscles, particularly stretching and
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Research has clearly shown that exercise is beneficial for spastic muscles, even though in the very early days of research it was assumed that strength exercise would
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Aloraini SM, Gäverth J, Yeung E, MacKay-Lyons M (18 February 2015). "Assessment of spasticity after stroke using clinical measures: a systematic review".
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A injection and various physical therapy modalities such as serial casting, sustained stretching and medical pharmacologic treatment. Spasticity in
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Bovend'Eerdt TJ, Newman M, Barker K, Dawes H, Minelli C, Wade DT (July 2008). "The effects of stretching in spasticity: a systematic review".
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could be required for a tendon release in the case of a severe muscle imbalance leading to contracture. In spastic CP, selective dorsal
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Muscles with severe spasticity are likely to be more limited in their ability to exercise, and may require help to do this. In spastic
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The initial focus on first activating contraction of antagonist muscles to provide reciprocal inhibition and lengthen spastic muscles
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patients labeled as "spastic" who actually demonstrate not just spasticity alone, but also an array of upper motor neuron findings.
1660:"Selection criteria for selective dorsal rhizotomy in children with spastic cerebral palsy: a systematic review of the literature" 236:
to rest in a more state. The combination of decreased inhibition and an increased depolarized state of cell membranes, decreases
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Reciprocal actions are attempted. Agonist contractions are performed first in small ranges progressing to larger arcs of movement
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Treatment should be based on assessment by relevant health professionals. For spastic muscles with mild-to-moderate impairment,
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muscle groups. Clonus is commonly seen in the ankle but may exist in other distal structures as well, such as the knee or spine.
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Patients and family/caregivers should be educated about the importance of maintaining range of motion and doing daily exercise
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Hillman M (2004). "Rehabilitation robotics from past to present: A historical perspective.". In Bien ZZ, Stefanov D (eds.).
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baclofen therapy (IBT) when spasticity. IBT may also be used in patients with limited tolerance to other modalities.
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resulting from hyper-excitability of the stretch reflex as one component of the upper motor neurone (UMN) syndrome".
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Hidler JM, Rymer WZ (September 1999). "A simulation study of reflex instability in spasticity: origins of clonus".
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Ivanhoe CB, Reistetter TA (October 2004). "Spasticity: the misunderstood part of the upper motor neuron syndrome".
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Hidler JM, Rymer WZ (September 1999). "A simulation study of reflex instability in spasticity: origins of clonus".
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in the affected region. This change in input to bodily structures tends to favor excitation and therefore increase
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Characteristic features, analogy, and pathophysiology of common types of hypertonia. GTO – Golgi Tendon Organ
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threshold) and is common in muscles with long conduction delays, such as the long reflex tracts found in
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Grunt, Sebastian; Fieggen, A Graham; Vermeulen, R Jeroen; Becher, Jules G; Langerak, Nelleke G (2014).
1854:"Strengthening interventions increase strength and improve activity after stroke: a systematic review" 334:, while in conditions like multiple sclerosis, spasticity is thought by some to be as a result of the 3922: 3618: 3435: 3324: 2850: 2318: 310: 1988: 840: 3547: 3194: 3049: 2989: 2882: 2784: 2707: 2154: 1941: 656: 626: 390: 1350:"Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy" 945:"'Seatbelt Effect' of spasticity: Contrasting velocity dependence from the clasp knife phenomenon" 92:. It is also colloquially referred to as an unusual "tightness", stiffness, or "pull" of muscles. 3917: 3717: 3702: 3690: 3440: 3391: 3228: 3091: 2979: 2619: 2609: 2604: 2513: 2378: 2276: 2185: 2046: 2009: 1834: 1772: 1733: 1478: 1425: 1271: 861: 808: 601: 548: 464: 422: 327: 273: 209: 205: 158: 142: 100: 2913: 1956: 1950: 735: 30:
For the societal implications of the term when applied as a label for a particular person, see
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and tip-toeing gait due to ankle equinus or ankle planter flexion deformity in spastic
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Wallace DM, Ross BH, Thomas CK (December 2005). "Motor unit behavior during clonus".
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Wallace DM, Ross BH, Thomas CK (December 2005). "Motor unit behavior during clonus".
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The clinical underpinnings of two of the most common spasticity conditions, spastic
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Lance JW (1980). "Symposium Synopsis". In Feldman RG, Young RR, Koella WP (eds.).
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children the main treatment modality of spasticity is conservative in the form of
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of spasticity, but which clinically is fundamentally different from the latter.
278: 197: 2107: 1906: 107:, an exaggerated deep tendon reflex. Spasticity is often treated with the drug 3174: 3044: 2825: 2643: 2638: 2629: 2558: 2492: 2482: 2420: 2343: 2085: 1626: 1577: 1474: 1311: 651: 507: 495: 402: 335: 89: 1720: 1703: 1702:
Kesiktas N, Paker N, Erdogan N, Gülsen G, Biçki D, Yilmaz H (December 2004).
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Farag SM, Mohammed MO, El-Sobky TA, ElKadery NA, ElZohiery AK (March 2020).
641: 597: 528: 499: 254: 57: 2042: 2005: 1914: 1879: 1830: 1729: 1685: 1644: 1595: 1562:"Pharmacological interventions for spasticity following spinal cord injury" 1421: 1383: 1329: 1267: 1232: 1183: 1103:"Intrathecal baclofen for the control of spinal and supraspinal spasticity" 1045: 988: 924: 857: 804: 34:. For the most common type of spasticity-based neuromuscular disorder, see 165:
and is thus unrelated to the types of spasticity present in neuromuscular
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CURRENT Diagnosis & Treatment: Physical Medicine & Rehabilitation
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Gross Motor Function Classification System - Expanded & Revised
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Spinal muscular atrophy with lower extremity predominance (SMALED)
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Gendy S, ElGebeily M, El-Sobky TA, Khoshhal KI, Jawadi AH (2019).
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Galey SA, Lerner ZF, Bulea TC, Zimbler S, Damiano DL (May 2017).
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Ramanathan, Venkateswaran; Baskar, Dipti; Pari, Hariswar (2022).
417:, so a thorough assessment requires this to be analysed as well. 2328: 2308: 2189: 116: 3847: 2917: 2158: 510:. If refractive to oral agents, spasticity may be treated with 1348:
Blumetti FC, Belloti JC, Tamaoki MJ, Pinto JA (October 2019).
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Clinically, spasticity results from the loss of inhibition of
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Louis Calder Memorial Library/Jackson Memorial Medical Center
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A general treatment guideline can be followed that involves:
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Medical interventions may include oral medications such as
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as a result of stroke or spinal cord injury, alter the of
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American Journal of Physical Medicine & Rehabilitation
1704:"The use of hydrotherapy for the management of spasticity" 753:. Chicago: Yearbook Medical Publishers. pp. 185–203. 480:
Highly stressful activities be minimized early in training
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Works about cerebral palsy and other paralytic syndromes
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are damaged or fail to develop normally; these include
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performance with a combination of paralysis, increased
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deficiencies present in the damaged nerves of spastic
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Management and Rehabilitation of Spinal Cord Injuries
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has also been used to decrease muscle overactivity.
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In the case of 192:Spasticity is found in conditions where the 1952:Willard and Spackman's occupational therapy 1697: 1695: 1615:The Cochrane Database of Systematic Reviews 1609:Shakespeare DT, Boggild M, Young C (2003). 1566:The Cochrane Database of Systematic Reviews 1354:The Cochrane Database of Systematic Reviews 1107:Upper Motor Neurone Syndrome and Spasticity 881:"Spasticity Mechanisms – for the Clinician" 483:Functional skills are targeted for training 232:excitability. CNS damage also causes nerve 3885: 3866: 3852: 3844: 3654: 3645: 3414: 3082: 3073: 2962: 2936: 2922: 2914: 2177: 2163: 2155: 2059: 1450:. Berlin: Springer-Verlag. pp. 25–44. 43: 1987: 1869: 1719: 1675: 1634: 1585: 1373: 1319: 1222: 1173: 1035: 978: 960: 914: 896: 839: 413:of an affected limb or the head from the 1402:Journal of Pediatric Orthopedics. Part B 708:. American Heart Association. April 2022 1858:The Australian Journal of Physiotherapy 693: 342:around nerve endings—which in turn can 99:, causing excessive velocity-dependent 3725:Distal hereditary motor neuronopathies 3398:Template:Demyelinating diseases of CNS 1949:Neistadt ME, Crepeau EB, eds. (1998). 354:children, leading to roughly the same 1708:Neurorehabilitation and Neural Repair 949:Annals of Indian Academy of Neurology 27:Abnormal stiffness of skeletal muscle 7: 3987:Manual Ability Classification System 3576:Idiopathic intracranial hypertension 1852:Ada L, Dorsch S, Canning CG (2006). 938: 936: 934: 751:Spasticity: Disordered Motor Control 62:physical medicine and rehabilitation 3807:Infantile progressive bulbar palsy 2227:Festinating gait/Parkinsonian gait 1823:10.1097/01.PHM.0000141125.28611.3E 365:As there are many features of the 25: 3510:Template:Cerebrovascular diseases 3313:Frontotemporal lobar degeneration 681:NINDS Spasticity Information Page 119:receptors, which are inhibitory. 3530:For more detailed coverage, see 3508:For more detailed coverage, see 3479:For more detailed coverage, see 3445:For more detailed coverage, see 3396:For more detailed coverage, see 2821:Overpronation/Flexible flat feet 1769:10.1097/00004356-200908001-00145 1101:Rushton, David N. (2008-04-24), 673: This article incorporates 668: 547:(FIM) scores of patients with a 1998:10.1152/japplphysiol.00649.2005 1518:. In Maitin IB, Cruz E (eds.). 850:10.1152/japplphysiol.00649.2005 545:Functional Independence Measure 1366:10.1002/14651858.CD001408.pub2 1166:10.1016/j.gaitpost.2017.02.024 580:clear regulations and trials. 245:; decreased movement control; 1: 3823:Amyotrophic lateral sclerosis 3708:Hereditary spastic paraplegia 3566:Normal pressure hydrocephalus 1976:Journal of Applied Physiology 1871:10.1016/s0004-9514(06)70003-4 1514:Saulino M, Goldman L (2014). 1260:10.3109/09638288.2015.1014933 1248:Disability and Rehabilitation 828:Journal of Applied Physiology 728:"Spasticity: Pathophysiology" 686:National Institutes of Health 305:Characteristics of spasticity 297:Characteristics of spasticity 169:rooted spasticity disorders. 4044:Cerebral palsy organizations 3967:General movements assessment 3792:Progressive muscular atrophy 2272:Myopathic gait/Waddling gait 1790:Bloch J (15 February 2016). 1414:10.1097/BPB.0000000000000503 1115:10.1017/cbo9780511544866.011 1002:Petek Balci, Belgin (2018). 3302:Primary progressive aphasia 1544:"UK Approves New Botox Use" 1073:10.1007/978-981-19-0228-4_3 1008:Archives of Neuropsychiatry 518:injections can be used, or 367:upper motor neuron syndrome 155:upper motor neuron syndrome 125:is the most common form of 103:. This ultimately leads to 4086: 4039:People with cerebral palsy 3624:Hashimoto's encephalopathy 3330:Posterior cortical atrophy 3151:Striatonigral degeneration 3002:Cavernous sinus thrombosis 1907:10.1016/j.apmr.2008.02.015 614:selective dorsal rhizotomy 612:treatment for spasticity, 608:there is also a permanent 238:action potential threshold 29: 3949:Dyskinetic cerebral palsy 3898:Upper motor neuron lesion 3730:Spinal muscular atrophies 3698:Primary lateral sclerosis 3556:Intracranial hypertension 3336:Creutzfeldt–Jakob disease 2673:Lower motor neuron lesion 2668:Upper motor neuron lesion 2473:Myotonia / Pseudomyotonia 2188:relating to movement and 1627:10.1002/14651858.CD001332 1578:10.1002/14651858.CD001131 1312:10.2106/JBJS.RVW.19.00119 399:rehabilitation physicians 3797:Progressive bulbar palsy 3588:Intracranial hypotension 3571:Choroid plexus papilloma 2985:Herpesviral encephalitis 1721:10.1177/1545968304270002 962:10.4103/aian.aian_817_21 898:10.3389/fneur.2010.00149 393:, physicians (including 348:gamma amino butyric acid 253:reflexes; and decreased 3999:Modified Ashworth scale 3944:Athetoid cerebral palsy 3309:Frontotemporal dementia 2995:Encephalitis lethargica 1498:Physical Rehabilitation 1475:10.1023/A:1024494031121 1447:Rehabilitation Robotics 1004:"Spasticty measurement" 632:Gamma-aminobutyric acid 456:rehabilitation robotics 407:occupational therapists 3983:(gross motor function) 3903:Spastic cerebral palsy 3614:Hepatic encephalopathy 1215:10.1051/sicotj/2019003 1059:Ko, Hyun-Yoon (2022), 885:Frontiers in Neurology 675:public domain material 306: 285:excitation (decreased 185: 139:central nervous system 123:Spastic cerebral palsy 3939:Ataxic cerebral palsy 3672:Ataxia–telangiectasia 3629:Static encephalopathy 3352:Mitochondrial disease 3190:Spasmodic torticollis 3100:Basal ganglia disease 2780:Boutonniere deformity 1496:O'Sullivan S (2007). 647:Stroke rehabilitation 304: 261:Spasticity and clonus 214:acquired brain injury 183: 4070:Cerebral palsy types 3923:Spastic quadriplegia 3619:Toxic encephalopathy 3325:Lewy bodies dementia 2851:Clasp-knife response 1014:(Suppl 1): S49–S53. 738:on 27 February 2010. 539:on spasticity, oral 311:Clasp-knife response 141:(CNS) affecting the 3667:Friedreich's ataxia 3050:Meningoencephalitis 2990:Limbic encephalitis 2883:Conversion disorder 2785:Swan neck deformity 2708:Locomotive syndrome 1942:University of Miami 1817:(10 Suppl): S3–S9. 657:Transverse myelitis 627:Brunnstrom Approach 602:muscle contractures 391:physical therapists 338:destruction of the 143:upper motor neurons 111:, which acts as an 3989:(manual dexterity) 3974:Measurement scales 3918:Spastic hemiplegia 3882:Symptoms and signs 3703:Pseudobulbar palsy 3441:Status epilepticus 3392:Multiple sclerosis 3229:Myoclonic epilepsy 3092:movement disorders 3038:Acute disseminated 2980:Viral encephalitis 2620:Spastic paraplegia 2610:Spastic paraplegia 2605:Periodic paralysis 2514:Abnormal posturing 2379:Dysdiadochokinesia 2315:Asynchronous gait 2277:Trendelenburg gait 2237:Marche Ă  petit pas 2186:Signs and symptoms 2118:External resources 1677:10.1111/dmcn.12277 1546:. 5 February 2014. 1154:Gait & Posture 1020:10.29399/npa.23339 549:spinal cord injury 465:spinal cord injury 423:muscle contracture 328:multiple sclerosis 307: 274:spinal cord injury 210:spinal cord injury 206:multiple sclerosis 186: 159:multiple sclerosis 101:muscle contraction 4057: 4056: 3957: 3956: 3932:Ataxia and others 3841: 3840: 3837: 3836: 3833: 3832: 3637: 3636: 3542: 3541: 3481:Template:Headache 3447:Template:Epilepsy 3368: 3367: 3342:Vascular dementia 3185:Status dystonicus 3058: 3057: 3033:Encephalomyelitis 2911: 2910: 2600:Flaccid paralysis 2421:Abnormal movement 2411:Hemimotor neglect 2369:Cerebellar ataxia 2319:Gunslinger's gait 2217:Cerebellar ataxia 2152: 2151: 2035:10.1109/86.788469 1966:978-0-397-55192-7 1944:. 3 October 2002. 1529:978-0-07-179329-2 1254:(25): 2313–2323. 1082:978-981-19-0227-7 797:10.1109/86.788469 760:978-0-88372-128-5 384:modified Ashworth 332:neonatal asphyxia 226:peripheral nerves 145:in the form of a 67: 66: 41:Medical condition 18:Spastic paralysis 16:(Redirected from 4077: 3913:Spastic diplegia 3886: 3868: 3861: 3854: 3845: 3655: 3646: 3604:Brain herniation 3415: 3255:Intention tremor 3250:Essential tremor 3115:Postencephalitic 3083: 3074: 2963: 2944:Diseases of the 2938: 2931: 2924: 2915: 2615:Spastic diplegia 2582:Tonic immobility 2574:Waxy flexibility 2518:Stooped posture 2324:Hemiparetic gait 2305:Asymmetric gait 2204:Gait abnormality 2179: 2172: 2165: 2156: 2060: 2054: 2017: 1991: 1982:(6): 2166–2172. 1970: 1945: 1919: 1918: 1901:(7): 1395–1406. 1890: 1884: 1883: 1873: 1849: 1843: 1842: 1806: 1800: 1799: 1787: 1781: 1780: 1751: 1742: 1741: 1723: 1699: 1690: 1689: 1679: 1655: 1649: 1648: 1638: 1606: 1600: 1599: 1589: 1557: 1548: 1547: 1540: 1534: 1533: 1511: 1502: 1501: 1493: 1487: 1486: 1463:Automatic Robots 1458: 1452: 1451: 1440: 1434: 1433: 1397: 1388: 1387: 1377: 1360:(10): CD001408. 1345: 1334: 1333: 1323: 1291: 1280: 1279: 1243: 1237: 1236: 1226: 1194: 1188: 1187: 1177: 1145: 1134: 1133: 1132: 1131: 1098: 1092: 1091: 1090: 1089: 1056: 1050: 1049: 1039: 999: 993: 992: 982: 964: 940: 929: 928: 918: 900: 876: 870: 869: 843: 834:(6): 2166–2172. 823: 817: 816: 780: 765: 764: 746: 740: 739: 734:. Archived from 724: 718: 717: 715: 713: 698: 689: 672: 671: 606:spastic diplegia 287:action potential 220:. Damage to the 151:spastic diplegia 44: 36:spastic diplegia 21: 4085: 4084: 4080: 4079: 4078: 4076: 4075: 4074: 4060: 4059: 4058: 4053: 4027: 4004: 3995:(communication) 3969: 3953: 3927: 3877: 3872: 3842: 3829: 3755:Congenital DSMA 3676: 3633: 3592: 3538: 3526:Sleep disorders 3514: 3491:Cerebrovascular 3485: 3451: 3408: 3402: 3364: 3346: 3271: 3217:Choreoathetosis 3090: 3067: 3054: 3018: 2952: 2942: 2912: 2907: 2878:Motion sickness 2811:Rachitic rosary 2799: 2748:Joint stiffness 2723:Range of motion 2717: 2684: 2680:Sleep paralysis 2664:General causes 2586: 2502: 2415: 2350: 2262:Vestibular gait 2242:Propulsive gait 2192: 2183: 2153: 2148: 2147: 2113: 2112: 2071: 2057: 2020: 1989:10.1.1.501.9581 1973: 1967: 1948: 1932: 1928: 1926:Further reading 1923: 1922: 1892: 1891: 1887: 1851: 1850: 1846: 1808: 1807: 1803: 1789: 1788: 1784: 1753: 1752: 1745: 1701: 1700: 1693: 1657: 1656: 1652: 1621:(4): CD001332. 1608: 1607: 1603: 1572:(2): CD001131. 1559: 1558: 1551: 1542: 1541: 1537: 1530: 1522:. McGraw Hill. 1513: 1512: 1505: 1495: 1494: 1490: 1460: 1459: 1455: 1442: 1441: 1437: 1399: 1398: 1391: 1347: 1346: 1337: 1293: 1292: 1283: 1245: 1244: 1240: 1196: 1195: 1191: 1147: 1146: 1137: 1129: 1127: 1125: 1100: 1099: 1095: 1087: 1085: 1083: 1058: 1057: 1053: 1001: 1000: 996: 942: 941: 932: 878: 877: 873: 841:10.1.1.501.9581 825: 824: 820: 782: 781: 768: 761: 748: 747: 743: 726: 725: 721: 711: 709: 700: 699: 695: 690: 678: 669: 666: 661: 622: 586: 574: 565: 520:botulinum toxin 447:botulinum toxin 431: 320: 299: 263: 135: 133:Pathophysiology 82:skeletal muscle 42: 39: 28: 23: 22: 15: 12: 11: 5: 4083: 4081: 4073: 4072: 4062: 4061: 4055: 4054: 4052: 4051: 4046: 4041: 4035: 4033: 4029: 4028: 4026: 4025: 4020: 4014: 4012: 4006: 4005: 4003: 4002: 3996: 3990: 3984: 3977: 3975: 3971: 3970: 3965: 3963: 3959: 3958: 3955: 3954: 3952: 3951: 3946: 3941: 3935: 3933: 3929: 3928: 3926: 3925: 3920: 3915: 3910: 3905: 3900: 3894: 3892: 3883: 3879: 3878: 3875:Cerebral palsy 3873: 3871: 3870: 3863: 3856: 3848: 3839: 3838: 3835: 3834: 3831: 3830: 3828: 3827: 3826: 3825: 3814: 3813: 3812: 3811: 3810: 3809: 3804: 3794: 3789: 3788: 3787: 3782: 3777: 3776: 3775: 3770: 3765: 3757: 3752: 3747: 3742: 3737: 3727: 3713: 3712: 3711: 3710: 3705: 3700: 3686: 3684: 3678: 3677: 3675: 3674: 3669: 3663: 3661: 3652: 3643: 3639: 3638: 3635: 3634: 3632: 3631: 3626: 3621: 3616: 3611: 3606: 3600: 3598: 3594: 3593: 3591: 3590: 3585: 3583:Cerebral edema 3580: 3579: 3578: 3573: 3568: 3563: 3552: 3550: 3544: 3543: 3540: 3539: 3537: 3536: 3535: 3534: 3532:Template:Sleep 3522: 3520: 3516: 3515: 3513: 3512: 3506: 3501: 3495: 3493: 3487: 3486: 3484: 3483: 3477: 3472: 3467: 3461: 3459: 3453: 3452: 3450: 3449: 3443: 3438: 3433: 3427: 3425: 3412: 3404: 3403: 3401: 3400: 3394: 3389: 3384: 3378: 3376: 3370: 3369: 3366: 3365: 3363: 3362: 3360:Leigh syndrome 3356: 3354: 3348: 3347: 3345: 3344: 3333: 3332: 3327: 3322: 3321: 3320: 3306: 3305: 3304: 3299: 3298: 3297: 3281: 3279: 3273: 3272: 3270: 3269: 3264: 3259: 3258: 3257: 3252: 3241: 3240: 3239: 3238: 3233: 3232: 3231: 3221: 3220: 3219: 3209: 3204: 3203: 3202: 3197: 3192: 3187: 3171: 3170: 3169: 3168: 3163: 3158: 3153: 3148: 3147: 3146: 3136: 3135: 3134: 3124: 3123: 3122: 3117: 3112: 3096: 3094: 3087:Extrapyramidal 3080: 3071: 3069:encephalopathy 3060: 3059: 3056: 3055: 3053: 3052: 3047: 3042: 3041: 3040: 3029: 3027: 3020: 3019: 3017: 3016: 3015: 3014: 3004: 2999: 2998: 2997: 2992: 2987: 2982: 2971: 2969: 2960: 2954: 2953: 2946:nervous system 2943: 2941: 2940: 2933: 2926: 2918: 2909: 2908: 2906: 2905: 2900: 2895: 2890: 2885: 2880: 2875: 2870: 2868:Astasia-abasia 2865: 2860: 2855: 2854: 2853: 2843: 2838: 2833: 2831:Bow-leggedness 2828: 2823: 2818: 2813: 2807: 2805: 2801: 2800: 2798: 2797: 2792: 2787: 2782: 2777: 2776: 2775: 2770: 2765: 2755: 2750: 2745: 2744: 2743: 2738: 2727: 2725: 2719: 2718: 2716: 2715: 2710: 2705: 2700: 2694: 2692: 2686: 2685: 2683: 2682: 2677: 2676: 2675: 2670: 2662: 2661: 2660: 2651: 2646: 2641: 2632: 2624: 2623: 2622: 2617: 2607: 2602: 2596: 2594: 2588: 2587: 2585: 2584: 2579: 2576: 2571: 2566: 2561: 2556: 2551: 2546: 2541: 2536: 2531: 2530: 2529: 2524: 2516: 2510: 2508: 2504: 2503: 2501: 2500: 2495: 2490: 2485: 2480: 2475: 2470: 2461: 2456: 2451: 2446: 2441: 2436: 2431: 2425: 2423: 2417: 2416: 2414: 2413: 2408: 2403: 2398: 2396:Sensory ataxia 2393: 2392: 2391: 2386: 2384:Pronator drift 2381: 2376: 2366: 2360: 2358: 2352: 2351: 2349: 2348: 2347: 2346: 2338: 2337: 2336: 2331: 2326: 2321: 2313: 2312: 2311: 2303: 2302: 2301: 2296: 2286: 2285: 2284: 2279: 2274: 2266: 2265: 2264: 2259: 2257:Truncal ataxia 2254: 2249: 2244: 2239: 2234: 2229: 2224: 2219: 2214: 2206: 2200: 2198: 2194: 2193: 2184: 2182: 2181: 2174: 2167: 2159: 2150: 2149: 2146: 2145: 2134: 2122: 2121: 2119: 2115: 2114: 2111: 2110: 2099: 2088: 2072: 2067: 2066: 2064: 2063:Classification 2056: 2055: 2029:(3): 327–340. 2018: 1971: 1965: 1946: 1929: 1927: 1924: 1921: 1920: 1885: 1864:(4): 241–248. 1844: 1801: 1782: 1743: 1714:(4): 268–273. 1691: 1670:(4): 302–312. 1650: 1601: 1549: 1535: 1528: 1503: 1488: 1453: 1435: 1408:(3): 221–230. 1389: 1335: 1281: 1238: 1189: 1135: 1123: 1093: 1081: 1051: 994: 955:(3): 517–519. 930: 871: 818: 791:(3): 327–340. 766: 759: 741: 719: 706:www.stroke.org 692: 691: 667: 665: 662: 660: 659: 654: 649: 644: 639: 637:Pronator drift 634: 629: 623: 621: 618: 585: 582: 573: 570: 564: 561: 534:Incorporating 488: 487: 484: 481: 478: 475: 451:cerebral palsy 443:cerebral palsy 430: 427: 375:cerebral palsy 352:cerebral palsy 340:myelin sheaths 324:cerebral palsy 319: 316: 298: 295: 262: 259: 234:cell membranes 202:cerebral palsy 167:cerebral palsy 163:myelin sheaths 134: 131: 127:cerebral palsy 88:activity, and 65: 64: 55: 49: 48: 40: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 4082: 4071: 4068: 4067: 4065: 4050: 4047: 4045: 4042: 4040: 4037: 4036: 4034: 4030: 4024: 4021: 4019: 4016: 4015: 4013: 4011: 4007: 4000: 3997: 3994: 3991: 3988: 3985: 3982: 3979: 3978: 3976: 3972: 3968: 3964: 3960: 3950: 3947: 3945: 3942: 3940: 3937: 3936: 3934: 3930: 3924: 3921: 3919: 3916: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3895: 3893: 3891: 3887: 3884: 3880: 3876: 3869: 3864: 3862: 3857: 3855: 3850: 3849: 3846: 3824: 3821: 3820: 3819: 3816: 3815: 3808: 3805: 3803: 3800: 3799: 3798: 3795: 3793: 3790: 3786: 3783: 3781: 3778: 3774: 3771: 3769: 3766: 3764: 3761: 3760: 3758: 3756: 3753: 3751: 3748: 3746: 3743: 3741: 3738: 3736: 3733: 3732: 3731: 3728: 3726: 3723: 3722: 3721: 3719: 3715: 3714: 3709: 3706: 3704: 3701: 3699: 3696: 3695: 3694: 3692: 3688: 3687: 3685: 3683: 3679: 3673: 3670: 3668: 3665: 3664: 3662: 3660: 3656: 3653: 3651: 3647: 3644: 3640: 3630: 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3609:Reye syndrome 3607: 3605: 3602: 3601: 3599: 3595: 3589: 3586: 3584: 3581: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3561:Hydrocephalus 3559: 3558: 3557: 3554: 3553: 3551: 3549: 3545: 3533: 3529: 3528: 3527: 3524: 3523: 3521: 3517: 3511: 3507: 3505: 3502: 3500: 3497: 3496: 3494: 3492: 3488: 3482: 3478: 3476: 3473: 3471: 3468: 3466: 3463: 3462: 3460: 3458: 3454: 3448: 3444: 3442: 3439: 3437: 3434: 3432: 3429: 3428: 3426: 3424: 3420: 3416: 3413: 3411: 3405: 3399: 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3379: 3377: 3375: 3374:Demyelinating 3371: 3361: 3358: 3357: 3355: 3353: 3349: 3343: 3340: 3339: 3338: 3337: 3331: 3328: 3326: 3323: 3319: 3316: 3315: 3314: 3310: 3307: 3303: 3300: 3296: 3293: 3292: 3291: 3288: 3287: 3286: 3283: 3282: 3280: 3278: 3274: 3268: 3265: 3263: 3262:Restless legs 3260: 3256: 3253: 3251: 3248: 3247: 3246: 3243: 3242: 3237: 3234: 3230: 3227: 3226: 3225: 3222: 3218: 3215: 3214: 3213: 3210: 3208: 3205: 3201: 3200:Blepharospasm 3198: 3196: 3193: 3191: 3188: 3186: 3183: 3182: 3181: 3178: 3177: 3176: 3173: 3172: 3167: 3164: 3162: 3159: 3157: 3156:Hemiballismus 3154: 3152: 3149: 3145: 3142: 3141: 3140: 3137: 3133: 3130: 3129: 3128: 3125: 3121: 3118: 3116: 3113: 3111: 3108: 3107: 3106: 3103: 3102: 3101: 3098: 3097: 3095: 3093: 3088: 3084: 3081: 3079: 3075: 3072: 3070: 3065: 3061: 3051: 3048: 3046: 3043: 3039: 3036: 3035: 3034: 3031: 3030: 3028: 3026: 3021: 3013: 3010: 3009: 3008: 3007:Brain abscess 3005: 3003: 3000: 2996: 2993: 2991: 2988: 2986: 2983: 2981: 2978: 2977: 2976: 2973: 2972: 2970: 2968: 2964: 2961: 2959: 2955: 2951: 2947: 2939: 2934: 2932: 2927: 2925: 2920: 2919: 2916: 2904: 2903:Dancing mania 2901: 2899: 2896: 2894: 2891: 2889: 2886: 2884: 2881: 2879: 2876: 2874: 2871: 2869: 2866: 2864: 2861: 2859: 2856: 2852: 2849: 2848: 2847: 2846:Hyperreflexia 2844: 2842: 2839: 2837: 2834: 2832: 2829: 2827: 2824: 2822: 2819: 2817: 2814: 2812: 2809: 2808: 2806: 2802: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2774: 2771: 2769: 2766: 2764: 2761: 2760: 2759: 2758:Hypermobility 2756: 2754: 2751: 2749: 2746: 2742: 2739: 2737: 2734: 2733: 2732: 2729: 2728: 2726: 2724: 2720: 2714: 2711: 2709: 2706: 2704: 2701: 2699: 2696: 2695: 2693: 2691: 2687: 2681: 2678: 2674: 2671: 2669: 2666: 2665: 2663: 2659: 2655: 2652: 2650: 2647: 2645: 2642: 2640: 2636: 2633: 2631: 2628: 2627: 2625: 2621: 2618: 2616: 2613: 2612: 2611: 2608: 2606: 2603: 2601: 2598: 2597: 2595: 2593: 2589: 2583: 2580: 2577: 2575: 2572: 2570: 2567: 2565: 2564:Joint locking 2562: 2560: 2557: 2555: 2552: 2550: 2547: 2545: 2542: 2540: 2537: 2535: 2532: 2528: 2525: 2523: 2520: 2519: 2517: 2515: 2512: 2511: 2509: 2505: 2499: 2496: 2494: 2491: 2489: 2486: 2484: 2481: 2479: 2476: 2474: 2471: 2469: 2465: 2462: 2460: 2457: 2455: 2452: 2450: 2447: 2445: 2444:Fasciculation 2442: 2440: 2437: 2435: 2432: 2430: 2427: 2426: 2424: 2422: 2418: 2412: 2409: 2407: 2404: 2402: 2399: 2397: 2394: 2390: 2387: 2385: 2382: 2380: 2377: 2375: 2372: 2371: 2370: 2367: 2365: 2362: 2361: 2359: 2357: 2353: 2345: 2342: 2341: 2339: 2335: 2334:Antalgic gait 2332: 2330: 2327: 2325: 2322: 2320: 2317: 2316: 2314: 2310: 2307: 2306: 2304: 2300: 2297: 2295: 2294:Steppage gait 2292: 2291: 2290: 2287: 2283: 2280: 2278: 2275: 2273: 2270: 2269: 2267: 2263: 2260: 2258: 2255: 2253: 2250: 2248: 2247:Stomping gait 2245: 2243: 2240: 2238: 2235: 2233: 2232:Magnetic gait 2230: 2228: 2225: 2223: 2220: 2218: 2215: 2213: 2210: 2209: 2207: 2205: 2202: 2201: 2199: 2195: 2191: 2187: 2180: 2175: 2173: 2168: 2166: 2161: 2160: 2157: 2144: 2140: 2139: 2135: 2133: 2129: 2128: 2124: 2123: 2120: 2116: 2109: 2105: 2104: 2100: 2098: 2094: 2093: 2089: 2087: 2083: 2082: 2078: 2074: 2073: 2070: 2065: 2061: 2052: 2048: 2044: 2040: 2036: 2032: 2028: 2024: 2019: 2015: 2011: 2007: 2003: 1999: 1995: 1990: 1985: 1981: 1977: 1972: 1968: 1962: 1958: 1954: 1953: 1947: 1943: 1939: 1935: 1931: 1930: 1925: 1916: 1912: 1908: 1904: 1900: 1896: 1889: 1886: 1881: 1877: 1872: 1867: 1863: 1859: 1855: 1848: 1845: 1840: 1836: 1832: 1828: 1824: 1820: 1816: 1812: 1805: 1802: 1797: 1793: 1786: 1783: 1778: 1774: 1770: 1766: 1762: 1758: 1750: 1748: 1744: 1739: 1735: 1731: 1727: 1722: 1717: 1713: 1709: 1705: 1698: 1696: 1692: 1687: 1683: 1678: 1673: 1669: 1665: 1661: 1654: 1651: 1646: 1642: 1637: 1632: 1628: 1624: 1620: 1616: 1612: 1605: 1602: 1597: 1593: 1588: 1583: 1579: 1575: 1571: 1567: 1563: 1556: 1554: 1550: 1545: 1539: 1536: 1531: 1525: 1521: 1517: 1510: 1508: 1504: 1499: 1492: 1489: 1484: 1480: 1476: 1472: 1468: 1464: 1457: 1454: 1449: 1446: 1439: 1436: 1431: 1427: 1423: 1419: 1415: 1411: 1407: 1403: 1396: 1394: 1390: 1385: 1381: 1376: 1371: 1367: 1363: 1359: 1355: 1351: 1344: 1342: 1340: 1336: 1331: 1327: 1322: 1317: 1313: 1309: 1305: 1301: 1297: 1290: 1288: 1286: 1282: 1277: 1273: 1269: 1265: 1261: 1257: 1253: 1249: 1242: 1239: 1234: 1230: 1225: 1220: 1216: 1212: 1208: 1204: 1200: 1193: 1190: 1185: 1181: 1176: 1171: 1167: 1163: 1159: 1155: 1151: 1144: 1142: 1140: 1136: 1126: 1124:9780521689786 1120: 1116: 1112: 1108: 1104: 1097: 1094: 1084: 1078: 1074: 1070: 1066: 1062: 1055: 1052: 1047: 1043: 1038: 1033: 1029: 1025: 1021: 1017: 1013: 1009: 1005: 998: 995: 990: 986: 981: 976: 972: 968: 963: 958: 954: 950: 946: 939: 937: 935: 931: 926: 922: 917: 912: 908: 904: 899: 894: 890: 886: 882: 875: 872: 867: 863: 859: 855: 851: 847: 842: 837: 833: 829: 822: 819: 814: 810: 806: 802: 798: 794: 790: 786: 779: 777: 775: 773: 771: 767: 762: 756: 752: 745: 742: 737: 733: 729: 723: 720: 707: 703: 697: 694: 687: 683: 682: 676: 663: 658: 655: 653: 650: 648: 645: 643: 640: 638: 635: 633: 630: 628: 625: 624: 619: 617: 615: 611: 610:neurosurgical 607: 603: 599: 595: 590: 583: 581: 578: 571: 569: 562: 560: 558: 554: 550: 546: 542: 537: 532: 530: 526: 521: 517: 513: 509: 505: 501: 497: 493: 485: 482: 479: 476: 473: 472: 471: 468: 466: 462: 457: 452: 448: 444: 439: 436: 428: 426: 424: 418: 416: 412: 411:stabilisation 408: 404: 400: 396: 392: 387: 385: 380: 376: 372: 368: 363: 359: 357: 353: 349: 345: 341: 337: 333: 329: 325: 317: 315: 312: 303: 296: 294: 292: 288: 284: 280: 275: 271: 267: 260: 258: 256: 252: 248: 244: 239: 235: 231: 227: 223: 219: 215: 211: 207: 203: 199: 195: 190: 182: 178: 174: 170: 168: 164: 160: 156: 152: 148: 144: 140: 132: 130: 128: 124: 120: 118: 114: 110: 106: 105:hyperreflexia 102: 98: 97:motor neurons 93: 91: 87: 86:tendon reflex 83: 79: 75: 71: 63: 59: 56: 54: 50: 45: 37: 33: 19: 4001:(spasticity) 3908:Scissor gait 3889: 3817: 3716: 3689: 3650:Degenerative 3387:Inflammatory 3334: 3267:Stiff-person 3105:Parkinsonism 3078:Degenerative 2975:Encephalitis 2958:Inflammation 2948:, primarily 2841:Hyporeflexia 2736:Bethlem sign 2703:Gowers' sign 2658:Quadruplegia 2534:Opisthotonus 2527:Osteoporosis 2522:Camptocormia 2464:Hyperkinesia 2449:Fibrillation 2356:Coordination 2309:Leaping gait 2252:Spastic gait 2222:Choreic gait 2212:Scissor gait 2136: 2125: 2101: 2090: 2075: 2026: 2022: 1979: 1975: 1951: 1937: 1898: 1894: 1888: 1861: 1857: 1847: 1814: 1810: 1804: 1795: 1785: 1760: 1756: 1711: 1707: 1667: 1663: 1653: 1618: 1614: 1604: 1569: 1565: 1538: 1519: 1516:"Spasticity" 1497: 1491: 1466: 1462: 1456: 1448: 1445:Advances in 1444: 1438: 1405: 1401: 1357: 1353: 1306:(3): e0119. 1303: 1300:JBJS Reviews 1299: 1251: 1247: 1241: 1206: 1202: 1192: 1157: 1153: 1128:, retrieved 1106: 1096: 1086:, retrieved 1064: 1054: 1011: 1007: 997: 952: 948: 888: 884: 874: 831: 827: 821: 788: 784: 750: 744: 736:the original 731: 722: 710:. Retrieved 705: 702:"Spasticity" 696: 680: 593: 591: 587: 577:Doublecortin 575: 566: 536:hydrotherapy 533: 489: 469: 440: 432: 419: 395:neurologists 388: 379:scissor gait 371:scissor gait 364: 360: 356:presentation 355: 343: 321: 308: 283:motor neuron 264: 242: 191: 187: 175: 171: 136: 121: 94: 77: 69: 68: 3802:Fazio–Londe 3642:Both/either 3436:Generalised 3295:Early-onset 3290:Alzheimer's 3025:spinal cord 2888:Shell shock 2863:Hypnic jerk 2763:Gorlin sign 2731:Contracture 2698:Hemiparesis 2654:Tetraplegia 2468:Hypokinesia 2389:Dyssynergia 2299:Toe walking 2282:Pigeon gait 2127:MedlinePlus 557:hemiparetic 543:dosage and 512:intrathecal 279:muscle tone 198:spinal cord 70:Spasticity 4010:Management 3890:Spasticity 3410:paroxysmal 3382:Autoimmune 3175:Dyskinesia 3045:Meningitis 3023:Brain and 2826:Knock-knee 2644:Hemiplegia 2639:Paraplegia 2630:Monoplegia 2626:Syndromes 2559:Hypertonia 2493:Echopraxia 2483:Stereotypy 2344:Lotus gait 2340:Deformity 2103:DiseasesDB 1160:: 93–105. 1130:2023-07-31 1088:2023-07-31 732:WeMove.org 664:References 652:Tizanidine 508:dantrolene 496:clonazepam 403:orthotists 377:children, 336:autoimmune 216:including 149:, such as 90:hypertonia 72:(from 47:Spasticity 4023:Rhizotomy 3962:Diagnosis 3407:Episodic/ 3285:Tauopathy 3236:Akathisia 3224:Myoclonus 3207:Athetosis 3139:Tauopathy 2898:Catatonia 2858:Shivering 2836:Back knee 2816:Flat feet 2790:Scoliosis 2753:Ankylosis 2741:Club foot 2649:Triplegia 2592:Paralysis 2578:Grimacing 2569:Catalepsy 2507:Posturing 2498:Echolalia 2488:Akathisia 2478:Hypotonia 2459:Myoclonus 2429:Athetosis 2401:Asterixis 2374:Dysmetria 2289:Foot drop 2268:Muscular 2143:neuro/706 2138:eMedicine 1984:CiteSeerX 1796:Ted Talks 1777:147336547 1028:1309-4866 971:0972-2327 907:1664-2295 836:CiteSeerX 642:Rhizotomy 598:splinting 563:Prognosis 529:rhizotomy 500:clonidine 429:Treatment 318:Diagnosis 255:endurance 58:Neurology 53:Specialty 4064:Category 3773:SMALED2B 3768:SMALED2A 3465:Migraine 3457:Headache 3423:epilepsy 3419:Seizures 3277:Dementia 3180:Dystonia 2795:Kyphosis 2690:Weakness 2635:Diplegia 2454:Myokymia 2051:18315004 2043:10498378 2006:16099891 1915:18534551 1880:17132118 1839:45445777 1831:15448572 1763:: S110. 1738:40066099 1730:15537997 1686:24106928 1645:14583932 1596:10796750 1483:39313352 1469:: 7–20. 1422:28953164 1384:31591703 1330:32224633 1268:25690684 1233:30816087 1184:28279852 1046:30692856 989:35936584 925:21206767 858:16099891 813:18315004 805:10498378 620:See also 594:increase 572:Research 541:baclofen 504:diazepam 492:baclofen 435:exercise 243:weakness 109:baclofen 78:spasmos- 3785:SMA-PME 3780:SMA-PCH 3763:SMALED1 3475:Tension 3470:Cluster 3195:Meige's 3012:Amoebic 2873:Vertigo 2544:Trismus 2097:D009128 2014:8598394 1636:7028001 1587:8406943 1430:4204446 1375:6779591 1321:7161716 1276:7432802 1224:6394235 1203:SICOT-J 1175:9619302 1037:6278623 980:9350785 916:3009478 891:: 149. 866:8598394 712:26 June 584:History 525:Surgery 461:strokes 196:and/or 113:agonist 32:Spastic 3504:Stroke 3318:Pick's 3245:Tremor 3212:Chorea 2893:Stupor 2713:Ptosis 2554:Tetany 2439:Tremor 2434:Chorea 2406:Abasia 2364:Ataxia 2132:003297 2049:  2041:  2012:  2004:  1986:  1963:  1913:  1878:  1837:  1829:  1775:  1736:  1728:  1684:  1643:  1633:  1594:  1584:  1526:  1481:  1428:  1420:  1382:  1372:  1328:  1318:  1274:  1266:  1231:  1221:  1182:  1172:  1121:  1079:  1044:  1034:  1026:  987:  977:  969:  923:  913:  905:  864:  856:  838:  811:  803:  757:  553:stroke 516:Phenol 291:distal 270:stroke 266:Clonus 251:tendon 247:clonus 218:stroke 147:lesion 4032:Other 3818:both: 3750:DSMA1 3745:SMAX2 3740:SMAX1 3720:only: 3693:only: 3597:Other 3519:Other 3431:Focal 3064:Brain 2967:Brain 2804:Other 2549:Cramp 2539:Spasm 2108:20872 2086:R25.2 2047:S2CID 2010:S2CID 1835:S2CID 1773:S2CID 1734:S2CID 1479:S2CID 1426:S2CID 1272:S2CID 1209:: 3. 862:S2CID 809:S2CID 677:from 506:, or 415:trunk 344:mimic 230:nerve 194:brain 153:, or 76: 74:Greek 3421:and 3132:PKAN 3127:NBIA 2329:Limp 2208:CNS 2197:Gait 2190:gait 2092:MeSH 2039:PMID 2002:PMID 1961:ISBN 1911:PMID 1876:PMID 1827:PMID 1726:PMID 1682:PMID 1641:PMID 1592:PMID 1570:2000 1524:ISBN 1418:PMID 1380:PMID 1358:2019 1326:PMID 1264:PMID 1229:PMID 1180:PMID 1119:ISBN 1077:ISBN 1042:PMID 1024:ISSN 985:PMID 967:ISSN 921:PMID 903:ISSN 854:PMID 801:PMID 755:ISBN 714:2022 405:and 397:and 346:the 326:and 272:and 212:and 117:GABA 3735:SMA 3718:LMN 3691:UMN 3682:MND 3548:CSF 3499:TIA 3144:PSP 3120:NMS 3089:and 2950:CNS 2773:HSD 2768:EDS 2077:ICD 2031:doi 1994:doi 1957:233 1903:doi 1866:doi 1819:doi 1765:doi 1716:doi 1672:doi 1631:PMC 1623:doi 1582:PMC 1574:doi 1471:doi 1410:doi 1370:PMC 1362:doi 1316:PMC 1308:doi 1256:doi 1219:PMC 1211:doi 1170:PMC 1162:doi 1111:doi 1069:doi 1032:PMC 1016:doi 975:PMC 957:doi 911:PMC 893:doi 846:doi 793:doi 401:), 222:CNS 115:at 4066:: 3659:SA 3166:OA 3161:HD 3110:PD 2656:/ 2637:/ 2466:/ 2141:: 2130:: 2106:: 2095:: 2084:: 2081:10 2045:. 2037:. 2025:. 2008:. 2000:. 1992:. 1980:99 1978:. 1959:. 1940:. 1936:. 1909:. 1899:89 1897:. 1874:. 1862:52 1860:. 1856:. 1833:. 1825:. 1815:83 1813:. 1794:. 1771:. 1761:32 1759:. 1746:^ 1732:. 1724:. 1712:18 1710:. 1706:. 1694:^ 1680:. 1668:56 1666:. 1662:. 1639:. 1629:. 1617:. 1613:. 1590:. 1580:. 1568:. 1564:. 1552:^ 1506:^ 1477:. 1467:15 1465:. 1424:. 1416:. 1406:27 1404:. 1392:^ 1378:. 1368:. 1356:. 1352:. 1338:^ 1324:. 1314:. 1302:. 1298:. 1284:^ 1270:. 1262:. 1252:37 1250:. 1227:. 1217:. 1205:. 1201:. 1178:. 1168:. 1158:54 1156:. 1152:. 1138:^ 1117:, 1105:, 1075:, 1063:, 1040:. 1030:. 1022:. 1012:55 1010:. 1006:. 983:. 973:. 965:. 953:25 951:. 947:. 933:^ 919:. 909:. 901:. 887:. 883:. 860:. 852:. 844:. 832:99 830:. 807:. 799:. 787:. 769:^ 730:. 704:. 684:. 555:, 502:, 498:, 494:, 257:. 208:, 204:, 60:, 3867:e 3860:t 3853:v 3311:/ 3066:/ 2937:e 2930:t 2923:v 2178:e 2171:t 2164:v 2079:- 2069:D 2053:. 2033:: 2027:7 2016:. 1996:: 1969:. 1917:. 1905:: 1882:. 1868:: 1841:. 1821:: 1798:. 1779:. 1767:: 1740:. 1718:: 1688:. 1674:: 1647:. 1625:: 1619:4 1598:. 1576:: 1532:. 1485:. 1473:: 1432:. 1412:: 1386:. 1364:: 1332:. 1310:: 1304:8 1278:. 1258:: 1235:. 1213:: 1207:5 1186:. 1164:: 1113:: 1071:: 1048:. 1018:: 991:. 959:: 927:. 895:: 889:1 868:. 848:: 815:. 795:: 789:7 763:. 716:. 688:. 38:. 20:)

Index

Spastic paralysis
Spastic
spastic diplegia
Specialty
Neurology
physical medicine and rehabilitation
Greek
skeletal muscle
tendon reflex
hypertonia
motor neurons
muscle contraction
hyperreflexia
baclofen
agonist
GABA
Spastic cerebral palsy
cerebral palsy
central nervous system
upper motor neurons
lesion
spastic diplegia
upper motor neuron syndrome
multiple sclerosis
myelin sheaths
cerebral palsy

brain
spinal cord
cerebral palsy

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