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344:, bacteria. Tyrothricin and its component antibiotics are too toxic to be taken internally but are sometimes used as topical antibiotics.
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Tyrothricin, and its component antibiotics, belongs to the pharmacologically related group of polypeptide antibiotic compounds including
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378:"Bactericidal fractions from an aerobic sporulating bacillus"
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359:. There is no cross-resistance to these three agents.
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317:in the late 1930s. It was later shown by Dubos and
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321:to be a mixture of two different antibiotics:
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332:Both gramicidin and tyrocidine are short
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376:Hotchkiss RD, Dubos RJ (December 1940).
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20:
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52:
7:
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307:mixture which was isolated from
385:Journal of Biological Chemistry
1:
398:10.1016/S0021-9258(18)73041-X
794:
286:
28:
54:International Drug Names
778:Polypeptide antibiotics
310:Brevibacillus brevis
624:Silver sulfadiazine
340:of some, primarily
25:
336:which disrupt the
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764:
761:
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607:Chemotherapeutics
601:
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484:Chlortetracycline
444:chemotherapeutics
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237:CompTox Dashboard
16:Chemical compound
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743:Ingenol mebutate
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319:Rollin Hotchkiss
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697:Podophyllotoxin
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521:Aminoglycosides
514:Chloramphenicol
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489:Oxytetracycline
472:and derivatives
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448:dermatological
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391:(3): 803–804.
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748:Metronidazole
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629:Sulfathiazole
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342:Gram-positive
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270:ECHA InfoCard
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253:DTXSID4045846
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38:Clinical data
36:
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27:
19:
753:Tirbanibulin
707:Tromantadine
616:Sulfonamides
587:
578:Fusidic acid
574:
546:Nadifloxacin
494:Tetracycline
470:Tetracycline
388:
384:
371:
346:
334:polypeptides
331:
308:
300:
299:
288:
226:ChEMBL577736
18:
722:Ibacitabine
677:Idoxuridine
672:Penciclovir
588:Tyrothricin
461:Antibiotics
440:Antibiotics
353:polymyxin B
301:Tyrothricin
276:100.014.337
106:Identifiers
23:Tyrothricin
692:Resiquimod
659:Antivirals
583:Bacitracin
542:Quinolones
530:Gentamicin
510:Amphenicol
363:References
357:bacitracin
327:tyrocidine
323:gramicidin
315:Rene Dubos
305:antibiotic
186:877376V2XW
157:ChemSpider
112:CAS Number
702:Docosanol
687:Imiquimod
682:Edoxudine
667:Aciclovir
593:Mupirocin
568:Rifaximin
564:Rifamycin
121:1404-88-2
48:Drugs.com
772:Category
717:Lysozyme
634:Mafenide
535:Amikacin
525:Neomycin
349:colistin
291:(verify)
62:ATC code
712:Inosine
132:PubChem
92: (
90:S01AA05
82: (
80:R02AB02
78:)
72: (
70:D06AX08
727:Lysine
575:other:
503:Others
355:, and
303:is an
217:ChEMBL
206:D06262
166:398608
146:452550
736:Other
450:use (
381:(PDF)
446:for
442:and
325:and
197:KEGG
177:UNII
44:AHFS
452:D06
393:doi
389:136
313:by
242:EPA
136:CID
95:WHO
85:WHO
75:WHO
774::
566::
555::
544::
523::
512::
387:.
383:.
351:,
329:.
88:)
454:)
432:e
425:t
418:v
401:.
395::
244:)
240:(
98:)
46:/
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