338:
315:
2699:
212:
237:
596:
589:
344:
243:
53:
2496:
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B,
1611:
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B,
79:
2372:
Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways".
2339:"Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR"
2698:
1507:
Thienpont B, Zhang L, Postma AV, Breckpot J, Tranchevent LC, Van Loo P, MΓΈllgΓ₯rd K, Tommerup N, Bache I, TΓΌmer Z, van
Engelen K, Menten B, Mortier G, Waggoner D, Gewillig M, Moreau Y, Devriendt K, Larsen LA (2010).
2050:
Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K (1996). "TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction".
2296:"Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol"
1963:"Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase"
2175:"Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6"
351:
250:
1401:"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro"
854:
835:
173:
2707:: Solution Structure of the N-terminal CUE Domain in the Human Mitogen-activated Protein Kinase Kinase Kinase 7 Interacting Protein 2 (MAP3K7IP2)
2678:
1381:
1363:
2727:
2097:"Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway"
1768:"Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway"
337:
76:
1090:
144:, CHTD2, MAP3K7IP2, TAB-2, TGF-beta activated kinase 1/MAP3K7 binding protein 2, TGF-beta activated kinase 1 (MAP3K7) binding protein 2
2253:"Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein"
1564:"Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein"
314:
1818:
Ma Q, Zhou L, Shi H, Huo K (Jun 2008). "NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation".
1451:"TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway"
1097:
1493:
1350:
1329:
1287:
1346:
1612:
Superti-Furga G (Feb 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway".
236:
211:
1325:
153:
2497:
Superti-Furga G (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway".
2218:"ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis"
1243:
350:
249:
2536:"A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes"
2671:
1904:"TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL"
343:
242:
899:
161:
880:
1449:
Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J, Matsumoto K (Jul 2000).
1399:
Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999).
2216:
Sanna MG, da Silva
Correia J, Luo Y, Chuang B, Paulson LM, Nguyen B, Deveraux QL, Ulevitch RJ (2002).
2017:"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones"
2664:
2059:
1915:
225:
140:
2140:"IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B"
1855:"PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination"
1073:
1048:
1040:
1036:
1010:
985:
973:
969:
595:
588:
2522:
2398:
2282:
2083:
1637:
1593:
185:
1069:
1044:
1006:
981:
977:
2173:
Mizukami J, Takaesu G, Akatsuka H, Sakurai H, Ninomiya-Tsuji J, Matsumoto K, Sakurai N (2002).
1494:"Entrez Gene: MAP3K7IP2 mitogen-activated protein kinase kinase kinase 7 interacting protein 2"
2633:
2612:
2592:
2557:
2514:
2484:
2441:
2390:
2360:
2325:
2274:
2239:
2204:
2161:
2126:
2075:
2038:
1992:
1943:
1884:
1835:
1797:
1745:
1689:
1629:
1585:
1539:
1472:
1422:
133:
69:
2582:
2547:
2506:
2474:
2466:
2431:
2423:
2382:
2350:
2315:
2307:
2264:
2229:
2194:
2186:
2151:
2116:
2108:
2067:
2028:
1982:
1974:
1933:
1923:
1874:
1866:
1827:
1787:
1779:
1735:
1727:
1679:
1671:
1621:
1575:
1529:
1521:
1462:
1412:
430:
361:
305:
260:
52:
405:
181:
37:
2063:
1919:
1214:. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by
2479:
2454:
1987:
1962:
1938:
1903:
1879:
1854:
1711:
1684:
1659:
1534:
1509:
2571:"TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains"
2569:
Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L, Chen ZJ (2004).
2436:
2411:
2320:
2295:
2269:
2252:
2199:
2174:
1740:
1715:
1580:
1563:
1467:
1450:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
688:
683:
678:
673:
668:
663:
647:
642:
637:
2721:
2642:
2621:
2311:
2121:
2096:
1792:
1767:
1179:
624:
2526:
2402:
2286:
2112:
2087:
1783:
1641:
1597:
165:
2410:
Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H, Gaynor RB, Matsumoto K (2004).
2190:
1234:. Mutations in MAP3K7IP2 have been associated with human congenital heart defects.
423:
202:
2071:
1831:
2587:
2570:
1928:
1870:
189:
1766:
Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K (Apr 2001).
1386:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1368:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1231:
2552:
2535:
1525:
506:
322:
219:
169:
1417:
1400:
2095:
Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K (2001).
2033:
2016:
1263:
1223:
799:
566:
444:
389:
376:
288:
275:
177:
2596:
2561:
2518:
2488:
2445:
2427:
2394:
2386:
2364:
2355:
2338:
2329:
2278:
2243:
2234:
2217:
2208:
2165:
2156:
2139:
2130:
2042:
1996:
1947:
1888:
1839:
1801:
1749:
1731:
1693:
1633:
1589:
1543:
1476:
17:
2079:
1902:
Walsh MC, Kim GK, Maurizio PL, Molnar EE, Choi Y (2008). Unutmaz D (ed.).
1426:
1137:
1132:
2337:
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X (2003).
1978:
1183:
1121:
944:
925:
2646:(Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 2) at the
2625:(Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2) at the
2647:
2637:
2626:
2616:
2470:
2015:
Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (2003).
1675:
1215:
1167:
911:
866:
1562:
Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG (Jul 2002).
1510:"Haploinsufficiency of TAB2 causes congenital heart defects in humans"
1150:
Mitogen-activated protein kinase kinase kinase 7-interacting protein 2
730:
nucleotide-binding oligomerization domain containing signaling pathway
110:
106:
102:
98:
1269:
1207:
1199:
1175:
1171:
1153:
1105:
821:
2510:
1625:
2251:
Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG (2002).
1299:
1293:
1281:
1275:
1251:
1219:
1211:
1195:
1187:
2412:"Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling"
1716:"Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling"
784:
780:
1257:
1227:
1203:
1160:
604:
157:
2660:
2138:
Qian Y, Commane M, Ninomiya-Tsuji J, Matsumoto K, Li X (2001).
643:
K63-linked polyubiquitin modification-dependent protein binding
2656:
1222:
through the activation of the receptor activator of NF-kappB (
1191:
710:
positive regulation of NF-kappaB transcription factor activity
2294:
Jiang Z, Ninomiya-Tsuji J, Qian Y, Matsumoto K, Li X (2002).
2632:
Overview of all the structural information available in the
2611:
Overview of all the structural information available in the
755:
positive regulation of I-kappaB kinase/NF-kappaB signaling
2455:"TAB3, a new binding partner of the protein kinase TAK1"
1660:"TAB3, a new binding partner of the protein kinase TAK1"
413:
1961:
Windheim M, Stafford M, Peggie M, Cohen P (Mar 2008).
1230:), which may regulate the development and function of
578:
1710:
Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H,
740:
stimulatory C-type lectin receptor signaling pathway
735:
MyD88-dependent toll-like receptor signaling pathway
1062:
1029:
999:
962:
1342:
1340:
1338:
1321:
1319:
1317:
360:
259:
1813:
1811:
1761:
1759:
1705:
1703:
1653:
1651:
29:Protein-coding gene in the species Homo sapiens
1557:
1555:
1553:
1488:
1486:
1444:
1442:
1440:
1438:
1436:
1347:GRCm38: Ensembl release 89: ENSMUSG00000015755
715:positive regulation of protein kinase activity
2672:
8:
1658:Cheung PC, Nebreda AR, Cohen P (Feb 2004).
1326:GRCh38: Ensembl release 89: ENSG00000055208
1194:. This protein forms a kinase complex with
2679:
2665:
2657:
795:
620:
401:
300:
197:
87:
2586:
2551:
2478:
2435:
2354:
2319:
2268:
2233:
2198:
2155:
2120:
2032:
1986:
1937:
1927:
1878:
1791:
1739:
1683:
1579:
1533:
1466:
1416:
1170:encoded by this gene is an activator of
765:interleukin-1-mediated signaling pathway
2694:
2453:Cheung PC, Nebreda AR, Cohen P (2004).
1313:
2534:Owerbach D, PiΓ±a L, Gabbay KH (2004).
42:
720:Fc-epsilon receptor signaling pathway
365:
326:
321:
264:
223:
218:
7:
1206:, thus serves as an adaptor linking
745:I-kappaB kinase/NF-kappaB signaling
553:migratory enteric neural crest cell
1853:Li S, Wang L, Dorf ME (Jan 2009).
1059:
1026:
996:
959:
935:
916:
890:
871:
845:
826:
583:
501:
439:
418:
25:
1156:that in humans is encoded by the
760:T cell receptor signaling pathway
2697:
2312:10.1128/MCB.22.20.7158-7167.2002
750:negative regulation of autophagy
594:
587:
521:extensor digitorum longus muscle
349:
342:
336:
313:
248:
241:
235:
210:
51:
2113:10.1128/MCB.21.7.2475-2484.2001
1784:10.1128/MCB.21.7.2475-2484.2001
1288:Nuclear receptor co-repressor 1
2191:10.1128/MCB.22.4.992-1000.2002
770:response to lipopolysaccharide
605:More reference expression data
567:More reference expression data
1:
2270:10.1016/S0092-8674(02)00809-7
2072:10.1126/science.272.5265.1179
1832:10.1016/j.cellsig.2008.01.015
1581:10.1016/S0092-8674(02)00809-7
1468:10.1016/S1097-2765(00)80244-0
487:muscle layer of sigmoid colon
334:
233:
2588:10.1016/j.molcel.2004.08.008
1929:10.1371/journal.pone.0004064
1871:10.1016/j.molcel.2008.11.023
1242:MAP3K7IP2 has been shown to
1178:, which is required for the
2728:Genes on human chromosome 6
32:For the metal compounds TaB
2744:
2553:10.2337/diabetes.53.7.1890
1714:, Matsumoto K (Dec 2003).
1526:10.1016/j.ajhg.2010.04.011
31:
2692:
1382:"Mouse PubMed Reference:"
1364:"Human PubMed Reference:"
1136:
1131:
1127:
1120:
1104:
1091:Chr 6: 149.22 β 149.41 Mb
1085:
1066:
1033:
1022:
1003:
966:
955:
942:
938:
923:
919:
910:
897:
893:
878:
874:
865:
852:
848:
833:
829:
820:
805:
798:
794:
778:
623:
619:
602:
586:
577:
564:
513:
504:
451:
442:
412:
404:
400:
383:
370:
333:
312:
303:
299:
282:
269:
232:
209:
200:
196:
151:
148:
138:
131:
126:
95:
90:
73:
68:
63:
59:
50:
45:
2387:10.1038/sj.onc.1206406
2356:10.1074/jbc.M300562200
2235:10.1074/jbc.M203312200
2157:10.1074/jbc.M102262200
1418:10.1093/dnares/5.5.277
1182:induced activation of
1098:Chr 10: 7.91 β 7.96 Mb
549:mesenteric lymph nodes
2034:10.1093/dnares/9.3.99
1184:nuclear factor kappaB
328:Chromosome 10 (mouse)
2428:10.1093/emboj/cdg605
1979:10.1128/MCB.02380-06
1732:10.1093/emboj/cdg605
467:gastrocnemius muscle
226:Chromosome 6 (human)
91:List of PDB id codes
64:Available structures
2064:1996Sci...272.1179S
1920:2008PLoSO...3.4064W
479:islet of Langerhans
463:epithelium of colon
2471:10.1042/BJ20031794
1676:10.1042/BJ20031794
900:ENSMUSG00000015755
698:Biological process
657:Cellular component
631:Molecular function
2715:
2714:
2058:(5265): 1179β82.
1147:
1146:
1143:
1142:
1116:
1115:
1081:
1080:
1056:
1055:
1018:
1017:
993:
992:
951:
950:
932:
931:
906:
905:
887:
886:
861:
860:
842:
841:
790:
789:
725:heart development
664:endosome membrane
638:metal ion binding
615:
614:
611:
610:
573:
572:
560:
559:
498:
497:
396:
395:
295:
294:
122:
121:
118:
117:
74:Ortholog search:
16:(Redirected from
2735:
2701:
2681:
2674:
2667:
2658:
2600:
2590:
2565:
2555:
2530:
2492:
2482:
2449:
2439:
2406:
2368:
2358:
2333:
2323:
2290:
2272:
2247:
2237:
2228:(34): 30454β62.
2212:
2202:
2169:
2159:
2134:
2124:
2091:
2046:
2036:
2001:
2000:
1990:
1958:
1952:
1951:
1941:
1931:
1899:
1893:
1892:
1882:
1850:
1844:
1843:
1815:
1806:
1805:
1795:
1763:
1754:
1753:
1743:
1707:
1698:
1697:
1687:
1655:
1646:
1645:
1608:
1602:
1601:
1583:
1559:
1548:
1547:
1537:
1504:
1498:
1497:
1490:
1481:
1480:
1470:
1446:
1431:
1430:
1420:
1396:
1390:
1389:
1378:
1372:
1371:
1360:
1354:
1344:
1333:
1323:
1129:
1128:
1100:
1093:
1076:
1060:
1051:
1027:
1023:RefSeq (protein)
1013:
997:
988:
960:
936:
917:
891:
872:
846:
827:
796:
621:
607:
598:
591:
584:
569:
529:genital tubercle
517:plantaris muscle
509:
507:Top expressed in
502:
471:cartilage tissue
459:ventricular zone
447:
445:Top expressed in
440:
419:
402:
392:
379:
368:
353:
346:
340:
329:
317:
301:
291:
278:
267:
252:
245:
239:
228:
214:
198:
192:
190:TAB2 - orthologs
143:
136:
113:
88:
82:
61:
60:
55:
43:
21:
2743:
2742:
2738:
2737:
2736:
2734:
2733:
2732:
2718:
2717:
2716:
2711:
2708:
2702:
2688:
2685:
2654:
2608:
2603:
2568:
2533:
2511:10.1038/ncb1086
2495:
2465:(Pt 1): 27β34.
2452:
2422:(23): 6277β88.
2409:
2381:(21): 3307β18.
2371:
2349:(19): 16713β9.
2336:
2306:(20): 7158β67.
2300:Mol. Cell. Biol
2293:
2250:
2215:
2185:(4): 992β1000.
2179:Mol. Cell. Biol
2172:
2150:(45): 41661β7.
2137:
2101:Mol. Cell. Biol
2094:
2049:
2014:
2010:
2008:Further reading
2005:
2004:
1967:Mol. Cell. Biol
1960:
1959:
1955:
1901:
1900:
1896:
1852:
1851:
1847:
1817:
1816:
1809:
1772:Mol. Cell. Biol
1765:
1764:
1757:
1726:(23): 6277β88.
1709:
1708:
1701:
1670:(Pt 1): 27β34.
1657:
1656:
1649:
1626:10.1038/ncb1086
1610:
1609:
1605:
1561:
1560:
1551:
1506:
1505:
1501:
1492:
1491:
1484:
1448:
1447:
1434:
1398:
1397:
1393:
1380:
1379:
1375:
1362:
1361:
1357:
1345:
1336:
1324:
1315:
1310:
1305:
1240:
1138:View/Edit Mouse
1133:View/Edit Human
1096:
1089:
1086:Location (UCSC)
1072:
1068:
1047:
1043:
1039:
1035:
1009:
1005:
984:
980:
976:
972:
968:
881:ENSG00000055208
774:
693:
679:plasma membrane
652:
648:protein binding
603:
593:
592:
565:
556:
551:
547:
543:
539:
535:
531:
527:
523:
519:
505:
494:
489:
485:
481:
477:
473:
469:
465:
461:
457:
443:
387:
374:
366:
356:
355:
354:
347:
327:
304:Gene location (
286:
273:
265:
255:
254:
253:
246:
224:
201:Gene location (
152:
139:
132:
97:
75:
41:
38:Tantalum boride
35:
30:
23:
22:
15:
12:
11:
5:
2741:
2739:
2731:
2730:
2720:
2719:
2713:
2712:
2710:
2709:
2703:
2696:
2693:
2690:
2689:
2686:
2684:
2683:
2676:
2669:
2661:
2652:
2651:
2630:
2607:
2606:External links
2604:
2602:
2601:
2566:
2531:
2499:Nat. Cell Biol
2493:
2450:
2407:
2369:
2334:
2291:
2248:
2213:
2170:
2135:
2107:(7): 2475β84.
2092:
2047:
2011:
2009:
2006:
2003:
2002:
1973:(5): 1783β91.
1953:
1894:
1845:
1826:(6): 1044β51.
1807:
1778:(7): 2475β84.
1755:
1699:
1647:
1614:Nat. Cell Biol
1603:
1549:
1514:Am J Hum Genet
1499:
1482:
1432:
1391:
1373:
1355:
1334:
1312:
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792:
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788:
787:
776:
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773:
772:
767:
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747:
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732:
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608:
600:
599:
581:
575:
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571:
570:
562:
561:
558:
557:
555:
554:
550:
546:
545:abdominal wall
542:
538:
534:
533:left lung lobe
530:
526:
522:
518:
514:
511:
510:
499:
496:
495:
493:
492:
491:biceps brachii
488:
484:
480:
476:
472:
468:
464:
460:
456:
452:
449:
448:
436:
435:
427:
416:
410:
409:
406:RNA expression
398:
397:
394:
393:
385:
381:
380:
372:
369:
364:
358:
357:
348:
341:
335:
331:
330:
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310:
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297:
296:
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284:
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268:
263:
257:
256:
247:
240:
234:
230:
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222:
216:
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207:
206:
194:
193:
150:
146:
145:
137:
129:
128:
124:
123:
120:
119:
116:
115:
93:
92:
84:
83:
72:
66:
65:
57:
56:
48:
47:
33:
28:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2740:
2729:
2726:
2725:
2723:
2706:
2700:
2695:
2691:
2682:
2677:
2675:
2670:
2668:
2663:
2662:
2659:
2655:
2649:
2645:
2644:
2639:
2635:
2631:
2628:
2624:
2623:
2618:
2614:
2610:
2609:
2605:
2598:
2594:
2589:
2584:
2581:(4): 535β48.
2580:
2576:
2572:
2567:
2563:
2559:
2554:
2549:
2546:(7): 1890β3.
2545:
2541:
2537:
2532:
2528:
2524:
2520:
2516:
2512:
2508:
2505:(2): 97β105.
2504:
2500:
2494:
2490:
2486:
2481:
2476:
2472:
2468:
2464:
2460:
2456:
2451:
2447:
2443:
2438:
2433:
2429:
2425:
2421:
2417:
2413:
2408:
2404:
2400:
2396:
2392:
2388:
2384:
2380:
2376:
2370:
2366:
2362:
2357:
2352:
2348:
2344:
2343:J. Biol. Chem
2340:
2335:
2331:
2327:
2322:
2317:
2313:
2309:
2305:
2301:
2297:
2292:
2288:
2284:
2280:
2276:
2271:
2266:
2262:
2258:
2254:
2249:
2245:
2241:
2236:
2231:
2227:
2223:
2222:J. Biol. Chem
2219:
2214:
2210:
2206:
2201:
2196:
2192:
2188:
2184:
2180:
2176:
2171:
2167:
2163:
2158:
2153:
2149:
2145:
2144:J. Biol. Chem
2141:
2136:
2132:
2128:
2123:
2118:
2114:
2110:
2106:
2102:
2098:
2093:
2089:
2085:
2081:
2077:
2073:
2069:
2065:
2061:
2057:
2053:
2048:
2044:
2040:
2035:
2030:
2027:(3): 99β106.
2026:
2022:
2018:
2013:
2012:
2007:
1998:
1994:
1989:
1984:
1980:
1976:
1972:
1968:
1964:
1957:
1954:
1949:
1945:
1940:
1935:
1930:
1925:
1921:
1917:
1914:(12): e4064.
1913:
1909:
1905:
1898:
1895:
1890:
1886:
1881:
1876:
1872:
1868:
1864:
1860:
1856:
1849:
1846:
1841:
1837:
1833:
1829:
1825:
1821:
1814:
1812:
1808:
1803:
1799:
1794:
1789:
1785:
1781:
1777:
1773:
1769:
1762:
1760:
1756:
1751:
1747:
1742:
1737:
1733:
1729:
1725:
1721:
1717:
1713:
1706:
1704:
1700:
1695:
1691:
1686:
1681:
1677:
1673:
1669:
1665:
1661:
1654:
1652:
1648:
1643:
1639:
1635:
1631:
1627:
1623:
1620:(2): 97β105.
1619:
1615:
1607:
1604:
1599:
1595:
1591:
1587:
1582:
1577:
1573:
1569:
1565:
1558:
1556:
1554:
1550:
1545:
1541:
1536:
1531:
1527:
1523:
1520:(6): 839β49.
1519:
1515:
1511:
1503:
1500:
1495:
1489:
1487:
1483:
1478:
1474:
1469:
1464:
1461:(4): 649β58.
1460:
1456:
1452:
1445:
1443:
1441:
1439:
1437:
1433:
1428:
1424:
1419:
1414:
1411:(5): 277β86.
1410:
1406:
1402:
1395:
1392:
1387:
1383:
1377:
1374:
1369:
1365:
1359:
1356:
1352:
1348:
1343:
1341:
1339:
1335:
1331:
1327:
1322:
1320:
1318:
1314:
1307:
1301:
1298:
1295:
1292:
1289:
1286:
1283:
1280:
1277:
1274:
1271:
1268:
1265:
1262:
1259:
1256:
1253:
1250:
1249:
1247:
1245:
1237:
1235:
1233:
1229:
1225:
1221:
1217:
1213:
1209:
1205:
1201:
1197:
1193:
1189:
1185:
1181:
1177:
1173:
1169:
1164:
1162:
1159:
1155:
1151:
1139:
1134:
1130:
1126:
1123:
1119:
1112:
1110:
1107:
1103:
1099:
1095:
1092:
1088:
1084:
1077:
1075:
1071:
1065:
1061:
1058:
1052:
1050:
1046:
1042:
1038:
1032:
1028:
1025:
1021:
1014:
1012:
1008:
1002:
998:
995:
989:
987:
983:
979:
975:
971:
965:
961:
958:
956:RefSeq (mRNA)
954:
947:
946:
941:
937:
934:
928:
927:
922:
918:
915:
913:
909:
902:
901:
896:
892:
889:
883:
882:
877:
873:
870:
868:
864:
857:
856:
851:
847:
844:
838:
837:
832:
828:
825:
823:
819:
816:
813:
811:
808:
804:
801:
797:
793:
786:
782:
777:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
706:
703:
702:
700:
697:
696:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
661:
659:
656:
655:
649:
646:
644:
641:
639:
636:
635:
633:
630:
629:
626:
625:Gene ontology
622:
618:
606:
601:
597:
590:
585:
582:
580:
576:
568:
563:
552:
548:
544:
540:
537:sciatic nerve
536:
532:
528:
525:parotid gland
524:
520:
516:
515:
512:
508:
503:
500:
490:
486:
482:
478:
475:hair follicle
474:
470:
466:
462:
458:
455:parotid gland
454:
453:
450:
446:
441:
438:
437:
434:
432:
428:
426:
425:
421:
420:
417:
415:
411:
407:
403:
399:
391:
386:
382:
378:
373:
367:10|10 A1
363:
359:
352:
345:
339:
332:
324:
320:
316:
311:
307:
302:
298:
290:
285:
281:
277:
272:
262:
258:
251:
244:
238:
231:
227:
221:
217:
213:
208:
204:
199:
195:
191:
187:
183:
179:
175:
171:
167:
163:
159:
155:
147:
142:
135:
130:
125:
114:
112:
108:
104:
100:
94:
89:
86:
85:
81:
78:
71:
67:
62:
58:
54:
49:
44:
39:
27:
19:
2704:
2653:
2641:
2620:
2578:
2574:
2543:
2539:
2502:
2498:
2462:
2458:
2419:
2415:
2378:
2374:
2346:
2342:
2303:
2299:
2263:(1): 55β67.
2260:
2256:
2225:
2221:
2182:
2178:
2147:
2143:
2104:
2100:
2055:
2051:
2024:
2020:
1970:
1966:
1956:
1911:
1907:
1897:
1865:(1): 30β42.
1862:
1858:
1848:
1823:
1820:Cell. Signal
1819:
1775:
1771:
1723:
1719:
1667:
1663:
1617:
1613:
1606:
1574:(1): 55β67.
1571:
1567:
1517:
1513:
1502:
1458:
1454:
1408:
1404:
1394:
1385:
1376:
1367:
1358:
1241:
1238:Interactions
1165:
1157:
1149:
1148:
1074:NP_001346463
1067:
1049:NP_001356435
1041:NP_001278964
1037:NP_001278963
1034:
1011:NM_001359534
1004:
986:NM_001369506
974:NM_001292035
970:NM_001292034
967:
943:
924:
898:
879:
853:
834:
814:
809:
541:aortic valve
429:
422:
287:149,411,613
274:149,218,641
149:External IDs
96:
26:
2687:PDB gallery
1232:osteoclasts
705:JNK cascade
689:nucleoplasm
127:Identifiers
18:TAB2 (gene)
2459:Biochem. J
1664:Biochem. J
1353:, May 2017
1332:, May 2017
1308:References
433:(ortholog)
388:7,956,230
375:7,905,653
170:HomoloGene
2575:Mol. Cell
1859:Mol. Cell
1712:Gaynor RB
1264:MAP3K7IP3
1224:TNFRSF11A
1158:MAP3K7IP2
1070:NP_619608
1045:NP_055908
1007:NM_138667
982:NM_145342
978:NM_015093
800:Orthologs
669:cytoplasm
178:GeneCards
2722:Category
2597:15327770
2562:15220215
2540:Diabetes
2527:11683986
2519:14743216
2489:14670075
2446:14633987
2403:38880905
2395:12761501
2375:Oncogene
2365:12609980
2330:12242293
2287:17679498
2279:12150997
2244:12048196
2209:11809792
2166:11518704
2131:11259596
2088:84807994
2043:12168954
1997:18180283
1948:19112497
1908:PLOS ONE
1889:19150425
1840:18299187
1802:11259596
1750:14633987
1694:14670075
1642:11683986
1634:14743216
1598:17679498
1590:12150997
1544:20493459
1477:10882101
1455:Mol Cell
1349:–
1328:–
1244:interact
1122:Wikidata
779:Sources:
674:membrane
483:monocyte
2648:PDBe-KB
2638:UniProt
2627:PDBe-KB
2617:UniProt
2480:1223947
2080:8638164
2060:Bibcode
2052:Science
2021:DNA Res
1988:2258775
1939:2603309
1916:Bibcode
1880:2643372
1685:1223947
1535:3032066
1427:9872452
1405:DNA Res
1351:Ensembl
1330:Ensembl
1216:TNFSF11
1168:protein
912:UniProt
867:Ensembl
806:Species
785:QuickGO
684:cytosol
408:pattern
166:1915902
134:Aliases
2643:Q99K90
2622:Q9NYJ8
2595:
2560:
2525:
2517:
2487:
2477:
2444:
2437:291846
2434:
2416:EMBO J
2401:
2393:
2363:
2328:
2321:139807
2318:
2285:
2277:
2242:
2207:
2200:134634
2197:
2164:
2129:
2119:
2086:
2078:
2041:
1995:
1985:
1946:
1936:
1887:
1877:
1838:
1800:
1790:
1748:
1741:291846
1738:
1720:EMBO J
1692:
1682:
1640:
1632:
1596:
1588:
1542:
1532:
1475:
1425:
1296:, and
1270:MAP3K7
1246:with:
1208:MAP3K7
1200:MAP3K7
1172:MAP3K7
1154:enzyme
1152:is an
1108:search
1106:PubMed
945:Q99K90
926:Q9NYJ8
822:Entrez
579:BioGPS
266:6q25.1
158:605101
36:, see
2523:S2CID
2399:S2CID
2283:S2CID
2122:86880
2084:S2CID
1793:86880
1638:S2CID
1594:S2CID
1300:TRAF6
1294:TRAF2
1282:NUMBL
1276:NFKB1
1252:HDAC3
1220:RANKL
1212:TRAF6
1196:TRAF6
1188:MAPK8
855:68652
836:23118
815:Mouse
810:Human
781:Amigo
431:Mouse
424:Human
371:Start
306:Mouse
270:Start
203:Human
2705:2dae
2636:for
2615:for
2593:PMID
2558:PMID
2515:PMID
2485:PMID
2442:PMID
2391:PMID
2361:PMID
2326:PMID
2275:PMID
2257:Cell
2240:PMID
2205:PMID
2162:PMID
2127:PMID
2076:PMID
2039:PMID
1993:PMID
1944:PMID
1885:PMID
1836:PMID
1798:PMID
1746:PMID
1690:PMID
1630:PMID
1586:PMID
1568:Cell
1540:PMID
1473:PMID
1423:PMID
1258:TAB1
1228:RANK
1210:and
1204:TAB1
1202:and
1186:and
1180:IL-1
1176:TAK1
1166:The
1161:gene
414:Bgee
362:Band
323:Chr.
261:Band
220:Chr.
182:TAB2
174:9019
154:OMIM
141:TAB2
111:2WX1
107:2WX0
103:2WWZ
99:2DAE
80:RCSB
77:PDBe
46:TAB2
2634:PDB
2613:PDB
2583:doi
2548:doi
2507:doi
2475:PMC
2467:doi
2463:378
2432:PMC
2424:doi
2383:doi
2351:doi
2347:278
2316:PMC
2308:doi
2265:doi
2261:110
2230:doi
2226:277
2195:PMC
2187:doi
2152:doi
2148:276
2117:PMC
2109:doi
2068:doi
2056:272
2029:doi
1983:PMC
1975:doi
1934:PMC
1924:doi
1875:PMC
1867:doi
1828:doi
1788:PMC
1780:doi
1736:PMC
1728:doi
1680:PMC
1672:doi
1668:378
1622:doi
1576:doi
1572:110
1530:PMC
1522:doi
1463:doi
1413:doi
1192:JNK
384:End
283:End
186:OMA
162:MGI
70:PDB
2724::
2640::
2619::
2591:.
2579:15
2577:.
2573:.
2556:.
2544:53
2542:.
2538:.
2521:.
2513:.
2501:.
2483:.
2473:.
2461:.
2457:.
2440:.
2430:.
2420:22
2418:.
2414:.
2397:.
2389:.
2379:22
2377:.
2359:.
2345:.
2341:.
2324:.
2314:.
2304:22
2302:.
2298:.
2281:.
2273:.
2259:.
2255:.
2238:.
2224:.
2220:.
2203:.
2193:.
2183:22
2181:.
2177:.
2160:.
2146:.
2142:.
2125:.
2115:.
2105:21
2103:.
2099:.
2082:.
2074:.
2066:.
2054:.
2037:.
2023:.
2019:.
1991:.
1981:.
1971:28
1969:.
1965:.
1942:.
1932:.
1922:.
1910:.
1906:.
1883:.
1873:.
1863:33
1861:.
1857:.
1834:.
1824:20
1822:.
1810:^
1796:.
1786:.
1776:21
1774:.
1770:.
1758:^
1744:.
1734:.
1724:22
1722:.
1718:.
1702:^
1688:.
1678:.
1666:.
1662:.
1650:^
1636:.
1628:.
1616:.
1592:.
1584:.
1570:.
1566:.
1552:^
1538:.
1528:.
1518:86
1516:.
1512:.
1485:^
1471:.
1457:.
1453:.
1435:^
1421:.
1407:.
1403:.
1384:.
1366:.
1337:^
1316:^
1198:,
1163:.
783:/
390:bp
377:bp
289:bp
276:bp
184:;
180::
176:;
172::
168:;
164::
160:;
156::
109:,
105:,
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