244:
221:
118:
143:
495:
250:
149:
1697:
1446:
Yustein JT, Xia L, Kahlenburg JM, et al. (2003). "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38".
1360:"Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress"
1304:
Zhang W, Chen T, Wan T, He L, Li N, Yuan Z, Cao X (Sep 2000). "Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways".
257:
156:
788:
769:
79:
1766:
1646:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
1742:
1245:
1761:
1227:
1519:
Hartmann TB, Thiel D, Dummer R, et al. (2004). "SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma".
1092:
243:
1099:
1599:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
220:
1339:
1265:"Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor"
1214:
1193:
142:
117:
1210:
1189:
59:
256:
155:
1735:
249:
148:
833:
67:
1558:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
814:
1728:
131:
1608:
1406:
46:
1071:
1067:
1042:
1038:
1034:
1030:
1026:
1022:
1012:
1008:
1004:
1000:
996:
972:
968:
943:
939:
935:
931:
927:
923:
913:
909:
905:
901:
897:
1632:
1544:
1472:
91:
1395:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1075:
1046:
976:
947:
1675:
1624:
1587:
1536:
1507:
1464:
1434:
1381:
1321:
1286:
494:
39:
1712:
1665:
1657:
1616:
1577:
1569:
1528:
1497:
1456:
1424:
1414:
1371:
1313:
1276:
336:
267:
211:
166:
87:
311:
1612:
1410:
1670:
1645:
1582:
1557:
1429:
1394:
703:
698:
693:
688:
683:
678:
673:
668:
663:
658:
653:
648:
643:
638:
633:
628:
623:
607:
602:
597:
592:
576:
571:
566:
561:
556:
551:
546:
541:
536:
1755:
1708:
1532:
523:
1548:
1476:
71:
1636:
329:
108:
95:
1250:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1232:
National Center for
Biotechnology Information, U.S. National Library of Medicine
412:
228:
125:
75:
1281:
1264:
1486:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
733:
472:
350:
295:
282:
194:
181:
83:
1679:
1628:
1591:
1540:
1511:
1468:
1460:
1438:
1419:
1385:
1376:
1359:
1325:
1317:
1290:
1139:
1134:
1123:
878:
859:
1620:
1661:
1573:
845:
800:
1155:
1107:
755:
1696:
1502:
1485:
1263:
Tassi E, Biesova Z, Di Fiore PP, Gutkind JS, Wong WT (Dec 1999).
718:
714:
1704:
1162:
503:
63:
1393:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
319:
1716:
1556:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1644:
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
484:
674:
positive regulation of stress-activated MAPK cascade
1060:
995:
961:
896:
1484:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1358:Yoneda T, Imaizumi K, Oono K, et al. (2001).
1206:
1204:
1202:
1185:
1183:
1181:
699:stress-activated protein kinase signaling cascade
266:
165:
16:Protein-coding gene in the species Homo sapiens
1211:GRCm38: Ensembl release 89: ENSMUSG00000061288
679:negative regulation of protein kinase activity
1736:
8:
1190:GRCh38: Ensembl release 89: ENSG00000135090
1743:
1729:
992:
893:
729:
664:mitotic G2 DNA damage checkpoint signaling
629:positive regulation of JUN kinase activity
519:
307:
206:
103:
1669:
1581:
1501:
1428:
1418:
1375:
1280:
50:, DPK, JIK, MAP3K18, TAO kinase 3, hKFC-A
644:cellular response to DNA damage stimulus
562:protein serine/threonine kinase activity
1177:
427:crypt of lieberkuhn of small intestine
20:
704:activation of protein kinase activity
271:
232:
227:
170:
129:
124:
7:
1693:
1691:
1152:Serine/threonine-protein kinase TAO3
1715:. You can help Knowledge (XXG) by
1057:
958:
869:
850:
824:
805:
779:
760:
649:negative regulation of JNK cascade
634:positive regulation of JNK cascade
489:
407:
345:
324:
14:
1340:"Entrez Gene: TAOK3 TAO kinase 3"
1158:that in humans is encoded by the
577:MAP kinase kinase kinase activity
552:protein kinase inhibitor activity
1695:
1533:10.1111/j.1365-2133.2004.05651.x
493:
255:
248:
242:
219:
154:
147:
141:
116:
689:regulation of apoptotic process
1767:Human chromosome 12 gene stubs
504:More reference expression data
473:More reference expression data
1:
240:
139:
1762:Genes on human chromosome 12
1399:Proc. Natl. Acad. Sci. U.S.A
659:protein autophosphorylation
381:superior vestibular nucleus
1783:
1690:
1306:Biochem Biophys Res Commun
1093:Chr 12: 118.15 – 118.37 Mb
684:nervous system development
459:retinal pigment epithelium
1246:"Mouse PubMed Reference:"
1228:"Human PubMed Reference:"
1138:
1133:
1129:
1122:
1106:
1100:Chr 5: 117.26 – 117.41 Mb
1087:
1064:
1019:
988:
965:
920:
889:
876:
872:
857:
853:
844:
831:
827:
812:
808:
799:
786:
782:
767:
763:
754:
739:
732:
728:
712:
522:
518:
501:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
1282:10.1074/jbc.274.47.33287
423:Rostral migratory stream
393:internal globus pallidus
389:external globus pallidus
654:protein phosphorylation
547:protein kinase activity
1461:10.1038/sj.onc.1206605
1420:10.1073/pnas.242603899
1377:10.1074/jbc.M010677200
1318:10.1006/bbrc.2000.3244
451:lateral septal nucleus
443:neural layer of retina
447:epithelium of stomach
385:middle temporal gyrus
132:Chromosome 12 (human)
537:transferase activity
431:ventromedial nucleus
234:Chromosome 5 (mouse)
1621:10.1038/nature04209
1613:2005Natur.437.1173R
1411:2002PNAS...9916899M
694:signal transduction
439:conjunctival fornix
373:epithelium of colon
1703:This article on a
1662:10.1101/gr.4039406
1574:10.1101/gr.2596504
834:ENSMUSG00000061288
617:Biological process
586:Cellular component
542:nucleotide binding
530:Molecular function
435:supraoptic nucleus
1724:
1723:
1405:(26): 16899–903.
1149:
1148:
1145:
1144:
1118:
1117:
1083:
1082:
1054:
1053:
984:
983:
955:
954:
885:
884:
866:
865:
840:
839:
821:
820:
795:
794:
776:
775:
724:
723:
514:
513:
510:
509:
479:
478:
466:
465:
404:
403:
377:bone marrow cells
302:
301:
201:
200:
96:TAOK3 - orthologs
1774:
1745:
1738:
1731:
1699:
1692:
1683:
1673:
1640:
1607:(7062): 1173–8.
1595:
1585:
1552:
1515:
1505:
1480:
1442:
1432:
1422:
1389:
1379:
1370:(17): 13935–40.
1344:
1343:
1336:
1330:
1329:
1301:
1295:
1294:
1284:
1275:(47): 33287–95.
1260:
1254:
1253:
1242:
1236:
1235:
1224:
1218:
1208:
1197:
1187:
1131:
1130:
1102:
1095:
1078:
1058:
1049:
993:
989:RefSeq (protein)
979:
959:
950:
894:
870:
851:
825:
806:
780:
761:
730:
520:
506:
497:
490:
475:
415:
413:Top expressed in
408:
361:secondary oocyte
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
1782:
1781:
1777:
1776:
1775:
1773:
1772:
1771:
1752:
1751:
1750:
1749:
1688:
1686:
1643:
1598:
1568:(10B): 2121–7.
1555:
1521:Br. J. Dermatol
1518:
1483:
1455:(40): 6129–41.
1445:
1392:
1357:
1353:
1351:Further reading
1348:
1347:
1338:
1337:
1333:
1303:
1302:
1298:
1262:
1261:
1257:
1244:
1243:
1239:
1226:
1225:
1221:
1209:
1200:
1188:
1179:
1174:
1168:
1140:View/Edit Mouse
1135:View/Edit Human
1098:
1091:
1088:Location (UCSC)
1074:
1070:
1066:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1015:
1011:
1007:
1003:
999:
975:
971:
967:
946:
942:
938:
934:
930:
926:
922:
916:
912:
908:
904:
900:
815:ENSG00000135090
708:
624:phosphorylation
612:
603:plasma membrane
581:
567:protein binding
557:kinase activity
502:
471:
462:
457:
455:mammillary body
453:
449:
445:
441:
437:
433:
429:
425:
411:
400:
397:corpus callosum
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
1780:
1778:
1770:
1769:
1764:
1754:
1753:
1748:
1747:
1740:
1733:
1725:
1722:
1721:
1700:
1685:
1684:
1641:
1596:
1553:
1516:
1503:10.1038/ng1285
1481:
1443:
1390:
1354:
1352:
1349:
1346:
1345:
1331:
1296:
1255:
1237:
1219:
1198:
1176:
1175:
1173:
1170:
1147:
1146:
1143:
1142:
1137:
1127:
1126:
1120:
1119:
1116:
1115:
1113:
1111:
1104:
1103:
1096:
1089:
1085:
1084:
1081:
1080:
1062:
1061:
1055:
1052:
1051:
1017:
1016:
990:
986:
985:
982:
981:
963:
962:
956:
953:
952:
918:
917:
891:
887:
886:
883:
882:
874:
873:
867:
864:
863:
855:
854:
848:
842:
841:
838:
837:
829:
828:
822:
819:
818:
810:
809:
803:
797:
796:
793:
792:
784:
783:
777:
774:
773:
765:
764:
758:
752:
751:
746:
741:
737:
736:
726:
725:
722:
721:
710:
709:
707:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
620:
618:
614:
613:
611:
610:
605:
600:
595:
589:
587:
583:
582:
580:
579:
574:
569:
564:
559:
554:
549:
544:
539:
533:
531:
527:
526:
516:
515:
512:
511:
508:
507:
499:
498:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
378:
374:
370:
369:jejunal mucosa
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
1779:
1768:
1765:
1763:
1760:
1759:
1757:
1746:
1741:
1739:
1734:
1732:
1727:
1726:
1720:
1718:
1714:
1710:
1709:chromosome 12
1706:
1701:
1698:
1694:
1689:
1681:
1677:
1672:
1667:
1663:
1659:
1655:
1651:
1647:
1642:
1638:
1634:
1630:
1626:
1622:
1618:
1614:
1610:
1606:
1602:
1597:
1593:
1589:
1584:
1579:
1575:
1571:
1567:
1563:
1559:
1554:
1550:
1546:
1542:
1538:
1534:
1530:
1526:
1522:
1517:
1513:
1509:
1504:
1499:
1495:
1491:
1487:
1482:
1478:
1474:
1470:
1466:
1462:
1458:
1454:
1450:
1444:
1440:
1436:
1431:
1426:
1421:
1416:
1412:
1408:
1404:
1400:
1396:
1391:
1387:
1383:
1378:
1373:
1369:
1365:
1364:J. Biol. Chem
1361:
1356:
1355:
1350:
1341:
1335:
1332:
1327:
1323:
1319:
1315:
1311:
1307:
1300:
1297:
1292:
1288:
1283:
1278:
1274:
1270:
1266:
1259:
1256:
1251:
1247:
1241:
1238:
1233:
1229:
1223:
1220:
1216:
1212:
1207:
1205:
1203:
1199:
1195:
1191:
1186:
1184:
1182:
1178:
1171:
1169:
1166:
1164:
1161:
1157:
1153:
1141:
1136:
1132:
1128:
1125:
1121:
1114:
1112:
1109:
1105:
1101:
1097:
1094:
1090:
1086:
1079:
1077:
1073:
1069:
1063:
1059:
1056:
1050:
1048:
1044:
1040:
1036:
1032:
1028:
1024:
1018:
1014:
1010:
1006:
1002:
998:
994:
991:
987:
980:
978:
974:
970:
964:
960:
957:
951:
949:
945:
941:
937:
933:
929:
925:
919:
915:
911:
907:
903:
899:
895:
892:
890:RefSeq (mRNA)
888:
881:
880:
875:
871:
868:
862:
861:
856:
852:
849:
847:
843:
836:
835:
830:
826:
823:
817:
816:
811:
807:
804:
802:
798:
791:
790:
785:
781:
778:
772:
771:
766:
762:
759:
757:
753:
750:
747:
745:
742:
738:
735:
731:
727:
720:
716:
711:
705:
702:
700:
697:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
621:
619:
616:
615:
609:
606:
604:
601:
599:
596:
594:
591:
590:
588:
585:
584:
578:
575:
573:
570:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
543:
540:
538:
535:
534:
532:
529:
528:
525:
524:Gene ontology
521:
517:
505:
500:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
1717:expanding it
1702:
1687:
1656:(1): 55–65.
1653:
1649:
1604:
1600:
1565:
1561:
1527:(2): 252–8.
1524:
1520:
1493:
1489:
1452:
1448:
1402:
1398:
1367:
1363:
1334:
1312:(3): 872–9.
1309:
1305:
1299:
1272:
1268:
1258:
1249:
1240:
1231:
1222:
1167:
1159:
1151:
1150:
1072:NP_001186614
1068:NP_001074777
1065:
1043:NP_001333426
1039:NP_001333425
1035:NP_001333424
1031:NP_001333423
1027:NP_001333422
1023:NP_001333421
1020:
1013:NP_001333420
1009:NP_001333419
1005:NP_001333418
1001:NP_001333417
997:NP_001333416
973:NM_001199685
969:NM_001081308
966:
944:NM_001346497
940:NM_001346496
936:NM_001346495
932:NM_001346494
928:NM_001346493
924:NM_001346492
921:
914:NM_001346491
910:NM_001346490
906:NM_001346489
902:NM_001346488
898:NM_001346487
877:
858:
832:
813:
787:
768:
748:
743:
639:MAPK cascade
335:
328:
294:117,413,284
281:117,258,194
193:118,372,907
180:118,149,801
55:External IDs
18:
1496:(1): 40–5.
1269:J Biol Chem
572:ATP binding
33:Identifiers
1756:Categories
1650:Genome Res
1562:Genome Res
1490:Nat. Genet
1217:, May 2017
1196:, May 2017
1172:References
669:DNA repair
339:(ortholog)
273:5|5 F
76:HomoloGene
1707:on human
1076:NP_899129
1047:NP_057365
977:NM_183306
948:NM_016281
734:Orthologs
593:cytoplasm
84:GeneCards
1680:16344560
1629:16189514
1592:15489334
1549:42495130
1541:14996095
1512:14702039
1477:21434404
1469:13679851
1449:Oncogene
1439:12477932
1386:11278723
1326:10924369
1291:10559204
1213:–
1192:–
1124:Wikidata
713:Sources:
598:membrane
365:monocyte
172:12q24.23
1671:1356129
1637:4427026
1609:Bibcode
1407:Bibcode
1215:Ensembl
1194:Ensembl
846:UniProt
801:Ensembl
740:Species
719:QuickGO
608:nucleus
314:pattern
72:3041177
40:Aliases
1678:
1668:
1635:
1627:
1601:Nature
1590:
1583:528928
1580:
1547:
1539:
1510:
1475:
1467:
1437:
1430:139241
1427:
1384:
1324:
1289:
1156:enzyme
1154:is an
1110:search
1108:PubMed
879:Q8BYC6
860:Q9H2K8
789:330177
756:Entrez
485:BioGPS
64:616711
1711:is a
1633:S2CID
1545:S2CID
1473:S2CID
1160:TAOK3
770:51347
749:Mouse
744:Human
715:Amigo
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
88:TAOK3
80:83279
47:TAOK3
24:TAOK3
1713:stub
1705:gene
1676:PMID
1625:PMID
1588:PMID
1537:PMID
1508:PMID
1465:PMID
1435:PMID
1382:PMID
1322:PMID
1287:PMID
1163:gene
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
1666:PMC
1658:doi
1617:doi
1605:437
1578:PMC
1570:doi
1529:doi
1525:150
1498:doi
1457:doi
1425:PMC
1415:doi
1372:doi
1368:276
1314:doi
1310:274
1277:doi
1273:274
290:End
189:End
92:OMA
68:MGI
1758::
1674:.
1664:.
1654:16
1652:.
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1615:.
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1201:^
1180:^
1165:.
717:/
296:bp
283:bp
195:bp
182:bp
90:;
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70::
66:;
62::
1744:e
1737:t
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94::
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