242:
219:
116:
141:
987:
1479:
1416:
1388:
248:
147:
996:
1270:
1023:
TBC1D30, also known as KIAA0984, is a protein in the 12th chromosome of the human genome at 12q14.3. The gene for the protein includes two domains: the RabGAP-TBC domain, and the DUF4682 domain. This gene spans 100,076 base pairs in the human genome, but gets condensed down into 7,931 bp for the mRNA
1248:
The first three in the list are independent of the reference genome. The latter 6, labelled with an X, are based on NC_000012.12 Reference GRCh38.p13 Primary
Assembly. The domains for each isoform that contains domains are the same RabGAB-TBC and DUF4682 domains. The size column shows the number of
1358:
TBC1D30 has a large amount of orthologs. Analysis of these homologs allow us to ascertain the most important amino acids, i.e., the ones that are conserved. The most highly conserved amino acids among vertebrates, invertebrates, fungi, plants, bacteria and protists with available sequences were
1359:
trp236, arg255, trp259, ile297, asp300, arg303, thr304, leu321, leu325, ala327, gly336, tyr337, cys338, gln339, leu349, glu356, pro399, trp432, trp450, asp451, arg463, and leu466. The RabGAP domain within the gene originated approximately 4 billion years ago, as it is present within
1538:. For the TBC1D30 line. Cytochrome C used Danio rerio, Zootermopsis nevadensis, Trichoplax, Saccharomyces cerevisiae, and Arabidopsis thaliana. Fibrinogen alpha used Homo sapiens, Macaca fascicularis, Mus musculus, Monodelphis domestica, Ornithorhynchus anatinus, and Gallus gallus.
990:
A prediction of the 3D structure of the TBC1D30 protein containing 275 of the 944 amino acids, including the RabGAP-TBC domain, modelled with 100% confidence. The colors show the direction of the protein, with red being the first amino acids, and blue/purple being the last amino
1990:
999:
A proposed 3D structure for the TBC1D30 protein. The colors show the direction of the protein according to the colors of the rainbow, with red being the start and blue/purple being the end of the protein, or amino acid
1370:
that diverged from humans 4.09 billion years ago. The whole gene likely originated approximately 1.3 billion years ago, as there are still amino acids conserved past the RabGAP domain, and into the DUF4682 domain for
2383:
255:
154:
687:
668:
77:
2016:"Knockdown of miR-194-5p inhibits cell proliferation, migration and invasion in breast cancer by regulating the Wnt/Ξ²-catenin signaling pathway"
2087:
2500:
1666:
1648:
2135:
1552:
241:
934:
927:
218:
1424:
1411:(California Two-Spot Octopus), RTo: Rhodotorula toruloides (Yeast). See Part B for the closer related orthologs to Homo sapiens.
1635:
1614:
1319:
2505:
1584:
140:
115:
1631:
1948:
1011:
that encodes the protein of the same name. This protein has two domains, one of which is involved in the processing of the
1610:
1015:
protein. Much of the function of this gene is not yet known, but it is expressed mostly in the brain and adrenal cortex.
57:
254:
153:
1924:
1428:
1408:
1391:
A) Unrooted phylogenetic tree of the most distant orthologs. PPu: Porphyridium purpureum (Red Marine
Microalga), TRo:
247:
146:
1396:
1373:
1503:
2457:
1531:
732:
65:
1966:
1556:
1523:
1404:
713:
2197:"Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3"
1483:
1468:
1456:
1323:
129:
2303:"The RNA-mediated estrogen receptor Ξ± interactome of hormone-dependent human breast cancer cell nuclei"
986:
2314:
2257:
1572:
1535:
44:
1515:
1495:
1452:
1400:
1379:
1281:
910:
885:
877:
873:
869:
843:
818:
814:
810:
806:
2358:
2301:
Nassa G, Giurato G, Salvati A, Gigantino V, Pecoraro G, Lamberti J, et al. (September 2019).
2477:
2088:"ELM - HSa_TBC1d30 XP_024304669.1 TBC1 domain family member 30 isoform X1 [Homo sapiens]"
1392:
1361:
89:
2407:
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, et al. (April 2010).
906:
881:
839:
802:
2438:
2340:
2283:
2226:
2045:
1718:
1587:), rs11615287, at the start of the RabGAP-TBC domain is likely to be damaging to the protein.
1568:
1258:
37:
1804:"PREDICTED: Homo sapiens TBC1 domain family member 30 (TBC1D30), transcript variant X1, mRNA"
85:
2469:
2428:
2420:
2330:
2322:
2273:
2265:
2216:
2208:
2035:
2027:
1708:
1700:
1560:
1448:
1284:
for TBC1D30 is about 1,279 base pairs, with a start at 64,779,516 and an end at 64,780,794.
334:
265:
209:
164:
1872:
1367:
1343:
1012:
309:
2318:
2261:
1478:
1415:
1387:
2433:
2408:
2335:
2302:
2278:
2245:
2221:
2196:
2040:
2015:
1713:
1688:
1511:
1440:
1335:
1803:
1785:
1261:
of about 8.5. Antibodies revealed TBC1D30 to have a molecular weight of about 90 kDa.
1234:
1229:
1213:
1208:
1192:
1187:
1171:
1166:
1150:
1145:
1129:
1124:
1108:
1103:
1087:
1082:
602:
597:
592:
587:
582:
566:
561:
556:
551:
546:
541:
525:
2494:
2481:
1303:
1292:
512:
1269:
995:
69:
2244:
Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, et al. (April 2020).
1849:"TBC1D30 TBC1 domain family member 30 [Homo sapiens (human)] - Gene - NCBI"
1821:
1564:
1487:
1472:
1444:
1322:
of the TBC1D30 gene for the hsa-miR-194-5p miRNA. This microRNA is involved in the
1066:
1061:
1008:
327:
106:
1822:"Homo sapiens TBC1 domain family member 30 (TBC1D30), transcript variant 1, mRNA"
1032:
There are 9 isoforms of TBC1D30, 3 of which are independent of the genome build.
93:
1671:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1653:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1499:
1436:
1347:
410:
2326:
2269:
2063:
1548:
1527:
226:
123:
73:
2195:
Vogel GF, Klee KM, Janecke AR, MΓΌller T, Hess MW, Huber LA (November 2015).
2156:
2111:
1519:
1420:
1339:
1288:
632:
470:
348:
293:
280:
192:
179:
81:
2442:
2344:
2287:
2230:
2049:
2031:
1722:
1704:
2424:
2212:
1848:
974:
969:
1764:
1507:
1460:
1315:
1024:
transcript, and finally 944 amino acids in its isoform X1 with 12 exons.
958:
777:
758:
2473:
1490:. The organisms included, in order of most recent to most distant, are
1273:
744:
699:
1384:
These two plants diverged from humans about 1.275 billions years ago.
1896:
1689:"The Phyre2 web portal for protein modeling, prediction and analysis"
942:
654:
1419:
B) Unrooted phylogenetic tree of the closer related orthologs. Dre:
1736:
1687:
Kelley LA, Mezulis S, Yates CM, Wass MN, Sternberg MJ (June 2015).
1482:
The rate of divergence, and thus evolution, is compared to that of
1590:
Studies have investigated how TBC1D30 affects insulin processing.
1491:
1477:
1432:
1414:
1386:
1299:
1268:
994:
985:
617:
613:
2409:"A method and server for predicting damaging missense mutations"
1786:"TBC1 domain family member 30 isoform X1 [Homo sapiens]"
61:
2456:
Parsons VA, Vadlamudi S, Moxley AH, Mohlke KL (June 21, 2021).
2172:
2170:
1737:"I-TASSER server for protein structure and function prediction"
2112:"Clustal Omega < Multiple Sequence Alignment < EMBL-EBI"
1298:
The protein is mostly found to be expressed in tissues of the
1287:
The TBC1D30 protein has been found in or associated with the
2177:
2151:
2149:
1991:"TargetScanHuman 8.0 predicted targeting of Human TBC1D30"
1276:
was completed on 95 individuals from 27 different tissues.
2384:"SNP linked to Gene (geneID:23329) Via Contig Annotation"
2246:"A reference map of the human binary protein interactome"
2458:"25-OR: Role for TBC1D30 in Secretion of Mature Insulin"
1471:, which evolves very quickly, but at a faster pace than
317:
1780:
1778:
1759:
1757:
482:
899:
862:
832:
795:
441:
dentate gyrus of hippocampal formation granule cell
1627:
1625:
1623:
1606:
1604:
1602:
1682:
1680:
264:
163:
1395:, ACa: Acanthamoeba castellanii str. Neff, LEr:
16:Protein-coding gene in the species Homo sapiens
1632:GRCm38: Ensembl release 89: ENSMUSG00000052302
8:
2020:International Journal of Molecular Medicine
1611:GRCh38: Ensembl release 89: ENSG00000111490
1467:The gene is evolving at a slower pace than
1034:
628:
508:
305:
204:
101:
2432:
2334:
2277:
2220:
2039:
2014:Yang F, Xiao Z, Zhang S (December 2018).
1712:
1427:(Western Terrestrial Garter Snake), MNe:
1559:. These interactions were found through
1226:TBC1 domain family member 30 isoform X6
1205:TBC1 domain family member 30 isoform X5
1184:TBC1 domain family member 30 isoform X4
1163:TBC1 domain family member 30 isoform X3
1142:TBC1 domain family member 30 isoform X2
1121:TBC1 domain family member 30 isoform X1
1903:. SIB Swiss Institute of Bioinformatics
1598:
1100:TBC1 domain family member 30 isoform 3
1079:TBC1 domain family member 30 isoform 2
1058:TBC1 domain family member 30 isoform 1
603:positive regulation of GTPase activity
583:negative regulation of cilium assembly
18:
1919:
1917:
1843:
1841:
1839:
1837:
1835:
1249:amino acids in each protein isoform.
269:
230:
225:
168:
127:
122:
7:
1431:(Southern Pig-Tailed Macaque), HSa:
1350:sites within the RabGAP-TBC domain.
1334:The protein contains some possible
2359:"TBC1D30 Result Summary | BioGRID"
1955:. Precigen Bioinformatics Germany.
1583:A Single Nucleotide Polymorphism (
896:
859:
829:
792:
768:
749:
723:
704:
678:
659:
487:
405:
343:
322:
14:
1873:"tbc1d30 human - Protein - NCBI"
453:lumbar subsegment of spinal cord
253:
246:
240:
217:
152:
145:
139:
114:
1949:"Genome Annotation and Browser"
598:intracellular protein transport
1925:"TBC1D30 Antibody (PA5-58923)"
1547:TBC1D30 likely interacts with
1036:Table 1. Isoforms for TBC1D30
471:More reference expression data
48:, TBC1 domain family member 30
1:
2157:"Multiple Sequence Alignment"
1897:"ExPASy - Compute pI/Mw tool"
1475:, which evolves very slowly.
588:activation of GTPase activity
238:
137:
2501:Genes on human chromosome 12
1459:(Two-Lined Caecilian), ECa:
1455:(Western Clawed Frog), RBi:
593:regulation of vesicle fusion
2201:The Journal of Cell Biology
1346:sites. There are also some
1310:Transcript level regulation
2522:
1397:Lithospermum erythrorhizon
1374:Lithospermum erythrorhizon
375:retinal pigment epithelium
2327:10.1038/s41597-019-0179-2
2270:10.1038/s41586-020-2188-x
1810:. NCBI. 22 November 2021.
1667:"Mouse PubMed Reference:"
1649:"Human PubMed Reference:"
1461:Erpetoichthys calabaricus
1451:(Green Sea Turtle), XTr:
1047:Protein Accession Number
973:
968:
964:
957:
941:
935:Chr 10: 121.1 β 121.19 Mb
922:
903:
866:
855:
836:
799:
788:
775:
771:
756:
752:
743:
730:
726:
711:
707:
698:
685:
681:
666:
662:
653:
638:
631:
627:
611:
526:GTPase activator activity
511:
507:
495:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2136:"Standard Protein BLAST"
1532:Saccharomyces cerevisiae
1508:Ornithorhynchus anatinus
1399:(Purple Gromwell), Nat:
1330:Protein level regulation
1318:binding site within the
928:Chr 12: 64.76 β 64.88 Mb
1743:. yangzhanglabumich.edu
1567:, affinity capture and
1524:Zootermopsis nevadensis
1443:(Red Junglefowl), ARo:
1407:(Nevada Termite), Obi:
1405:Zootermopsis nevadensis
1403:(Coyote Tobacco), ZNe:
1295:from antibody studies.
2032:10.3892/ijmm.2018.3897
1828:. NCBI. 17 April 2022.
1705:10.1038/nprot.2015.053
1539:
1464:
1412:
1354:Homology and evolution
1277:
1001:
992:
429:neural layer of retina
425:superior frontal gyrus
2506:Human genome projects
2425:10.1038/nmeth0410-248
2213:10.1083/jcb.201506112
1579:Clinical significance
1504:Monodelphis domestica
1481:
1457:Rhinatrema bivittatum
1447:(Okarito kiwi), CMy:
1418:
1390:
1272:
1265:Gene level regulation
1044:RNA Accession Number
998:
989:
421:primary visual cortex
371:primary visual cortex
367:middle temporal gyrus
232:Chromosome 10 (mouse)
130:Chromosome 12 (human)
2388:www.ncbi.nlm.nih.gov
1971:www.ncbi.nlm.nih.gov
1967:"GDS596 / 213912_at"
1929:www.thermofisher.com
1877:www.ncbi.nlm.nih.gov
1853:www.ncbi.nlm.nih.gov
1573:two-hybrid screening
1543:Interacting proteins
1536:Arabidopsis thaliana
1439:(House Mouse), GGa:
1409:Octopus bimaculoides
437:olfactory epithelium
433:primary motor cortex
2319:2019NatSD...6..173N
2262:2020Natur.580..402L
1769:UCSC Genome Browser
1496:Macaca fascicularis
1401:Nicotiana attenuata
1380:Nicotiana attenuata
1326:signaling pathway.
1037:
552:endomembrane system
383:islet of Langerhans
94:TBC1D30 - orthologs
2474:10.2337/db21-25-OR
1995:www.targetscan.org
1540:
1516:Xenopus tropicalis
1465:
1453:Xenopus tropicalis
1425:Thamnophis elegans
1423:(Zebrafish), TEl:
1413:
1393:Terriglobus roseus
1362:Terriglobus roseus
1278:
1035:
1002:
993:
733:ENSMUSG00000052302
576:Biological process
542:ciliary basal body
535:Cellular component
519:Molecular function
2256:(7803): 402β408.
1569:mass spectrometry
1429:Macaca nemestrina
1259:isoelectric point
1246:
1245:
1007:is a gene in the
984:
983:
980:
979:
953:
952:
918:
917:
893:
892:
851:
850:
826:
825:
784:
783:
765:
764:
739:
738:
720:
719:
694:
693:
675:
674:
623:
622:
503:
502:
499:
498:
477:
476:
464:
463:
449:prefrontal cortex
445:cerebellar cortex
402:
401:
391:postcentral gyrus
300:
299:
199:
198:
2513:
2486:
2485:
2453:
2447:
2446:
2436:
2404:
2398:
2397:
2395:
2394:
2380:
2374:
2373:
2371:
2370:
2355:
2349:
2348:
2338:
2298:
2292:
2291:
2281:
2241:
2235:
2234:
2224:
2192:
2186:
2185:
2174:
2165:
2164:
2153:
2144:
2143:
2132:
2126:
2125:
2123:
2122:
2108:
2102:
2101:
2099:
2098:
2084:
2078:
2077:
2075:
2074:
2068:myhits.sib.swiss
2060:
2054:
2053:
2043:
2026:(6): 3355β3363.
2011:
2005:
2004:
2002:
2001:
1987:
1981:
1980:
1978:
1977:
1963:
1957:
1956:
1945:
1939:
1938:
1936:
1935:
1921:
1912:
1911:
1909:
1908:
1893:
1887:
1886:
1884:
1883:
1869:
1863:
1862:
1860:
1859:
1845:
1830:
1829:
1818:
1812:
1811:
1800:
1794:
1793:
1782:
1773:
1772:
1761:
1752:
1751:
1749:
1748:
1733:
1727:
1726:
1716:
1693:Nature Protocols
1684:
1675:
1674:
1663:
1657:
1656:
1645:
1639:
1629:
1618:
1608:
1561:affinity capture
1484:Fibrinogen alpha
1469:Fibrinogen alpha
1324:Wnt/Beta-catenin
1280:The most likely
1041:Transcript Name
1038:
966:
965:
937:
930:
913:
897:
888:
860:
856:RefSeq (protein)
846:
830:
821:
793:
769:
750:
724:
705:
679:
660:
629:
509:
488:
473:
413:
411:Top expressed in
406:
395:Brodmann area 46
379:body of pancreas
363:Brodmann area 23
359:endothelial cell
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
2521:
2520:
2516:
2515:
2514:
2512:
2511:
2510:
2491:
2490:
2489:
2455:
2454:
2450:
2406:
2405:
2401:
2392:
2390:
2382:
2381:
2377:
2368:
2366:
2357:
2356:
2352:
2307:Scientific Data
2300:
2299:
2295:
2243:
2242:
2238:
2194:
2193:
2189:
2176:
2175:
2168:
2155:
2154:
2147:
2134:
2133:
2129:
2120:
2118:
2110:
2109:
2105:
2096:
2094:
2086:
2085:
2081:
2072:
2070:
2062:
2061:
2057:
2013:
2012:
2008:
1999:
1997:
1989:
1988:
1984:
1975:
1973:
1965:
1964:
1960:
1947:
1946:
1942:
1933:
1931:
1923:
1922:
1915:
1906:
1904:
1895:
1894:
1890:
1881:
1879:
1871:
1870:
1866:
1857:
1855:
1847:
1846:
1833:
1826:NCBI Nucleotide
1820:
1819:
1815:
1808:NCBI Nucleotide
1802:
1801:
1797:
1784:
1783:
1776:
1763:
1762:
1755:
1746:
1744:
1735:
1734:
1730:
1686:
1685:
1678:
1665:
1664:
1660:
1647:
1646:
1642:
1630:
1621:
1609:
1600:
1596:
1581:
1545:
1356:
1344:phosphorylation
1332:
1312:
1293:plasma membrane
1267:
1257:TBC1D30 has an
1255:
1030:
1021:
975:View/Edit Mouse
970:View/Edit Human
933:
926:
923:Location (UCSC)
909:
905:
884:
880:
876:
872:
868:
842:
838:
817:
813:
809:
805:
801:
714:ENSG00000111490
607:
571:
562:plasma membrane
530:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
2519:
2517:
2509:
2508:
2503:
2493:
2492:
2488:
2487:
2448:
2419:(4): 248β249.
2413:Nature Methods
2399:
2375:
2365:. TyersLab.com
2350:
2293:
2236:
2207:(3): 587β604.
2187:
2166:
2145:
2127:
2103:
2079:
2055:
2006:
1982:
1958:
1940:
1913:
1901:web.expasy.org
1888:
1864:
1831:
1813:
1795:
1774:
1765:"Blat Results"
1753:
1728:
1699:(6): 845β858.
1676:
1658:
1640:
1619:
1597:
1595:
1592:
1580:
1577:
1575:respectively.
1544:
1541:
1449:Chelonia mydas
1368:acidobacterium
1355:
1352:
1336:myristoylation
1331:
1328:
1311:
1308:
1304:adrenal glands
1266:
1263:
1254:
1251:
1244:
1243:
1240:
1237:
1235:XP_016874576.1
1232:
1230:XM_017019087.2
1227:
1223:
1222:
1219:
1216:
1214:XP_024304672.1
1211:
1209:XM_024448904.1
1206:
1202:
1201:
1198:
1195:
1193:XP_011536380.1
1190:
1188:XM_011538078.2
1185:
1181:
1180:
1177:
1174:
1172:XP_024304671.1
1169:
1167:XM_024448903.1
1164:
1160:
1159:
1156:
1153:
1151:XP_024304670.1
1148:
1146:XM_024448902.1
1143:
1139:
1138:
1135:
1132:
1130:XP_024304669.1
1127:
1125:XM_024448901.1
1122:
1118:
1117:
1114:
1111:
1109:NP_001317116.1
1106:
1104:NM_001330187.2
1101:
1097:
1096:
1093:
1090:
1088:NP_001317115.1
1085:
1083:NM_001330186.2
1080:
1076:
1075:
1072:
1069:
1067:NP_001317117.1
1064:
1059:
1055:
1054:
1051:
1048:
1045:
1042:
1029:
1026:
1020:
1017:
982:
981:
978:
977:
972:
962:
961:
955:
954:
951:
950:
948:
946:
939:
938:
931:
924:
920:
919:
916:
915:
901:
900:
894:
891:
890:
864:
863:
857:
853:
852:
849:
848:
834:
833:
827:
824:
823:
797:
796:
790:
786:
785:
782:
781:
773:
772:
766:
763:
762:
754:
753:
747:
741:
740:
737:
736:
728:
727:
721:
718:
717:
709:
708:
702:
696:
695:
692:
691:
683:
682:
676:
673:
672:
664:
663:
657:
651:
650:
645:
640:
636:
635:
625:
624:
621:
620:
609:
608:
606:
605:
600:
595:
590:
585:
579:
577:
573:
572:
570:
569:
564:
559:
554:
549:
544:
538:
536:
532:
531:
529:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
457:pontine nuclei
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2518:
2507:
2504:
2502:
2499:
2498:
2496:
2483:
2479:
2475:
2471:
2467:
2463:
2459:
2452:
2449:
2444:
2440:
2435:
2430:
2426:
2422:
2418:
2414:
2410:
2403:
2400:
2389:
2385:
2379:
2376:
2364:
2360:
2354:
2351:
2346:
2342:
2337:
2332:
2328:
2324:
2320:
2316:
2312:
2308:
2304:
2297:
2294:
2289:
2285:
2280:
2275:
2271:
2267:
2263:
2259:
2255:
2251:
2247:
2240:
2237:
2232:
2228:
2223:
2218:
2214:
2210:
2206:
2202:
2198:
2191:
2188:
2183:
2179:
2173:
2171:
2167:
2162:
2161:Clustal Omega
2158:
2152:
2150:
2146:
2141:
2137:
2131:
2128:
2117:
2116:www.ebi.ac.uk
2113:
2107:
2104:
2093:
2089:
2083:
2080:
2069:
2065:
2059:
2056:
2051:
2047:
2042:
2037:
2033:
2029:
2025:
2021:
2017:
2010:
2007:
1996:
1992:
1986:
1983:
1972:
1968:
1962:
1959:
1954:
1950:
1944:
1941:
1930:
1926:
1920:
1918:
1914:
1902:
1898:
1892:
1889:
1878:
1874:
1868:
1865:
1854:
1850:
1844:
1842:
1840:
1838:
1836:
1832:
1827:
1823:
1817:
1814:
1809:
1805:
1799:
1796:
1791:
1787:
1781:
1779:
1775:
1770:
1766:
1760:
1758:
1754:
1742:
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1732:
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1724:
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1715:
1710:
1706:
1702:
1698:
1694:
1690:
1683:
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1677:
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1668:
1662:
1659:
1654:
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1644:
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1633:
1628:
1626:
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1620:
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1607:
1605:
1603:
1599:
1593:
1591:
1588:
1586:
1578:
1576:
1574:
1570:
1566:
1562:
1558:
1554:
1550:
1542:
1537:
1533:
1529:
1525:
1521:
1517:
1513:
1512:Gallus gallus
1509:
1505:
1501:
1497:
1493:
1489:
1485:
1480:
1476:
1474:
1470:
1462:
1458:
1454:
1450:
1446:
1442:
1441:Gallus gallus
1438:
1434:
1430:
1426:
1422:
1417:
1410:
1406:
1402:
1398:
1394:
1389:
1385:
1383:
1381:
1376:
1375:
1369:
1365:
1363:
1353:
1351:
1349:
1345:
1341:
1337:
1329:
1327:
1325:
1321:
1317:
1309:
1307:
1305:
1301:
1296:
1294:
1290:
1285:
1283:
1275:
1271:
1264:
1262:
1260:
1252:
1250:
1241:
1238:
1236:
1233:
1231:
1228:
1225:
1224:
1220:
1217:
1215:
1212:
1210:
1207:
1204:
1203:
1199:
1196:
1194:
1191:
1189:
1186:
1183:
1182:
1178:
1175:
1173:
1170:
1168:
1165:
1162:
1161:
1157:
1154:
1152:
1149:
1147:
1144:
1141:
1140:
1136:
1133:
1131:
1128:
1126:
1123:
1120:
1119:
1115:
1112:
1110:
1107:
1105:
1102:
1099:
1098:
1094:
1091:
1089:
1086:
1084:
1081:
1078:
1077:
1073:
1070:
1068:
1065:
1063:
1060:
1057:
1056:
1052:
1049:
1046:
1043:
1040:
1039:
1033:
1027:
1025:
1018:
1016:
1014:
1010:
1006:
997:
988:
976:
971:
967:
963:
960:
956:
949:
947:
944:
940:
936:
932:
929:
925:
921:
914:
912:
908:
902:
898:
895:
889:
887:
883:
879:
875:
871:
865:
861:
858:
854:
847:
845:
841:
835:
831:
828:
822:
820:
816:
812:
808:
804:
798:
794:
791:
789:RefSeq (mRNA)
787:
780:
779:
774:
770:
767:
761:
760:
755:
751:
748:
746:
742:
735:
734:
729:
725:
722:
716:
715:
710:
706:
703:
701:
697:
690:
689:
684:
680:
677:
671:
670:
665:
661:
658:
656:
652:
649:
646:
644:
641:
637:
634:
630:
626:
619:
615:
610:
604:
601:
599:
596:
594:
591:
589:
586:
584:
581:
580:
578:
575:
574:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
543:
540:
539:
537:
534:
533:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
271:10|10 D2
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
2465:
2461:
2451:
2416:
2412:
2402:
2391:. Retrieved
2387:
2378:
2367:. Retrieved
2362:
2353:
2310:
2306:
2296:
2253:
2249:
2239:
2204:
2200:
2190:
2181:
2160:
2139:
2130:
2119:. Retrieved
2115:
2106:
2095:. Retrieved
2091:
2082:
2071:. Retrieved
2067:
2064:"Motif Scan"
2058:
2023:
2019:
2009:
1998:. Retrieved
1994:
1985:
1974:. Retrieved
1970:
1961:
1952:
1943:
1932:. Retrieved
1928:
1905:. Retrieved
1900:
1891:
1880:. Retrieved
1876:
1867:
1856:. Retrieved
1852:
1825:
1816:
1807:
1798:
1790:NCBI Protein
1789:
1768:
1745:. Retrieved
1740:
1731:
1696:
1692:
1670:
1661:
1652:
1643:
1589:
1582:
1565:Western blot
1546:
1500:Mus musculus
1492:Homo sapiens
1488:Cytochrome C
1473:Cytochrome C
1466:
1463:(Reed Fish).
1445:Apteryx rowi
1437:Mus musculus
1433:Homo sapiens
1378:
1372:
1366:which is an
1360:
1357:
1333:
1313:
1297:
1286:
1279:
1256:
1247:
1031:
1022:
1009:human genome
1004:
1003:
911:NP_001347944
904:
886:NP_001351767
878:NP_001317117
874:NP_001317116
870:NP_001317115
867:
844:NM_001361015
837:
819:NM_001364838
815:NM_001330188
811:NM_001330187
807:NM_001330186
800:
776:
757:
731:
712:
686:
667:
647:
642:
333:
326:
292:121,187,183
279:121,099,725
53:External IDs
1520:Danio rerio
1421:Danio rerio
1348:degradation
1314:There is a
1062:NM_015279.2
1028:Transcripts
191:64,881,033
178:64,759,484
31:Identifiers
2495:Categories
2393:2021-12-09
2369:2021-12-17
2313:(1): 173.
2178:"TimeTree"
2121:2021-12-09
2097:2021-12-09
2092:elm.eu.org
2073:2021-12-09
2000:2021-12-09
1976:2021-12-08
1934:2021-12-09
1907:2021-12-08
1882:2021-12-09
1858:2021-12-08
1747:2021-12-09
1638:, May 2017
1617:, May 2017
1594:References
1528:Trichoplax
337:(ortholog)
74:HomoloGene
2482:237885967
1953:Genomatix
1741:Zhang Lab
1340:amination
1289:cytoplasm
1000:sequence.
907:NP_083333
882:NP_056094
840:NM_029057
803:NM_015279
633:Orthologs
82:GeneCards
2462:Diabetes
2443:20354512
2345:31527615
2288:32296183
2231:26553929
2182:TimeTree
2050:30272253
1723:25950237
1634:–
1613:–
1316:microRNA
1291:and the
1282:promoter
1071:761 aa
1053:Domains
959:Wikidata
612:Sources:
547:membrane
387:testicle
2434:2855889
2363:BioGRID
2336:6746822
2315:Bibcode
2279:7169983
2258:Bibcode
2222:4639860
2163:. EMBL.
2142:. NCBI.
2041:6202083
1792:. NCBI.
1714:5298202
1636:Ensembl
1615:Ensembl
1435:, MMu:
1274:RNA-seq
1253:Protein
1239:647 aa
1218:667 aa
1197:781 aa
1176:900 aa
1155:924 aa
1134:944 aa
1113:647 aa
1092:737 aa
1005:TBC1D30
745:UniProt
700:Ensembl
639:Species
618:QuickGO
557:cytosol
312:pattern
170:12q14.3
86:TBC1D30
70:1921944
45:TBC1D30
38:Aliases
22:TBC1D30
2480:
2441:
2431:
2343:
2333:
2286:
2276:
2250:Nature
2229:
2219:
2048:
2038:
1721:
1711:
1571:, and
1553:ZRANB1
1534:, and
1486:, and
1342:, and
1320:3' UTR
991:acids.
945:search
943:PubMed
778:Q69ZT9
759:Q9Y2I9
655:Entrez
567:cilium
483:BioGPS
62:615077
2478:S2CID
2140:BLAST
1300:brain
1050:Size
688:74694
669:23329
648:Mouse
643:Human
614:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:18930
2439:PMID
2341:PMID
2284:PMID
2227:PMID
2046:PMID
1719:PMID
1563:and
1557:ESR1
1555:and
1549:STX3
1377:and
1302:and
1019:Gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
2470:doi
2429:PMC
2421:doi
2331:PMC
2323:doi
2274:PMC
2266:doi
2254:580
2217:PMC
2209:doi
2205:211
2036:PMC
2028:doi
1709:PMC
1701:doi
1585:SNP
1013:Rab
491:n/a
288:End
187:End
90:OMA
66:MGI
2497::
2476:.
2468:.
2466:70
2464:.
2460:.
2437:.
2427:.
2415:.
2411:.
2386:.
2361:.
2339:.
2329:.
2321:.
2309:.
2305:.
2282:.
2272:.
2264:.
2252:.
2248:.
2225:.
2215:.
2203:.
2199:.
2180:.
2169:^
2159:.
2148:^
2138:.
2114:.
2090:.
2066:.
2044:.
2034:.
2024:42
2022:.
2018:.
1993:.
1969:.
1951:.
1927:.
1916:^
1899:.
1875:.
1851:.
1834:^
1824:.
1806:.
1788:.
1777:^
1767:.
1756:^
1739:.
1717:.
1707:.
1697:10
1695:.
1691:.
1679:^
1669:.
1651:.
1622:^
1601:^
1551:,
1530:,
1526:,
1522:,
1518:,
1514:,
1510:,
1506:,
1502:,
1498:,
1494:,
1338:,
1306:.
1242:2
1221:2
1200:2
1179:2
1158:2
1137:2
1116:2
1095:0
1074:2
616:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
2484:.
2472::
2445:.
2423::
2417:7
2396:.
2372:.
2347:.
2325::
2317::
2311:6
2290:.
2268::
2260::
2233:.
2211::
2184:.
2124:.
2100:.
2076:.
2052:.
2030::
2003:.
1979:.
1937:.
1910:.
1885:.
1861:.
1771:.
1750:.
1725:.
1703::
1673:.
1655:.
1382:.
1364:,
212:)
109:)
92::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.