242:
219:
116:
141:
248:
147:
1451:
Halatsch ME, Löw S, Mursch K, Hielscher T, Schmidt U, Unterberg A, Vougioukas VI, Feuerhake F (Aug 2009). "Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib. Laboratory investigation".
1375:
Balaz P, Plaschke J, Krüger S, Görgens H, Schackert HK (Aug 2010). "TCF-3, 4 protein expression correlates with beta-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers".
1413:
Salins P, Shawesh S, He Y, Dibrov A, Kashour T, Arthur G, Amara F (Feb 2007). "Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling".
1524:
Velasco J, Zarrabeitia MT, Prieto JR, Perez-Castrillon JL, Perez-Aguilar MD, Perez-Nuñez MI, Sañudo C, Hernandez-Elena J, Calvo I, Ortiz F, Gonzalez-Macias J, Riancho JA (Jan 2010).
1188:
Sagara N, Katoh M (Nov 2000). "Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down-regulation".
255:
154:
717:
698:
77:
1099:
1081:
1790:
1211:"Identification of replicative senescence-associated genes in human umbilical vein endothelial cells by an annealing control primer system"
1608:
Lukas J, Mazna P, Valenta T, Doubravska L, Pospichalova V, Vojtechova M, Fafilek B, Ivanek R, Plachy J, Novak J, Korinek V (May 2009).
241:
1332:"INTS6/DICE1 inhibits growth of human androgen-independent prostate cancer cells by altering the cell cycle profile and Wnt signaling"
925:
932:
218:
1068:
1047:
1011:
1651:
Ollila HM, Soronen P, Silander K, Palo OM, Kieseppä T, Kaunisto MA, Lönnqvist J, Peltonen L, Partonen T, Paunio T (Apr 2009).
1795:
1696:"Activation of the canonical wingless/T-cell factor signaling pathway promotes invasive differentiation of human trophoblast"
1064:
140:
115:
1120:
1043:
1800:
57:
254:
153:
1694:
Pollheimer J, Loregger T, Sonderegger S, Saleh L, Bauer S, Bilban M, Czerwenka K, Husslein P, Knöfler M (Apr 2006).
247:
146:
1293:
Katoh M (Jan 2007). "Networking of WNT, FGF, Notch, BMP, and
Hedgehog signaling pathways during carcinogenesis".
1252:"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score"
762:
65:
1653:"Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort"
1526:"Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study"
1015:
743:
1007:
999:
129:
44:
1019:
904:
853:
1596:
1553:
1439:
1401:
1318:
1238:
89:
908:
883:
857:
832:
1768:
1725:
1682:
1639:
1588:
1545:
1512:
1483:"Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium"
1469:
1431:
1393:
1363:
1310:
1281:
1230:
1197:
1176:
37:
1758:
1750:
1715:
1707:
1672:
1664:
1629:
1621:
1578:
1537:
1502:
1494:
1461:
1423:
1385:
1353:
1343:
1302:
1271:
1263:
1222:
1166:
1158:
334:
265:
209:
164:
85:
309:
1720:
1695:
1677:
1652:
1634:
1609:
1507:
1482:
1358:
1331:
1330:
Filleur S, Hirsch J, Wille A, Schön M, Sell C, Shearer MH, Nelius T, Wieland I (2009).
1276:
1251:
995:
1583:
1566:
1498:
1171:
1146:
632:
627:
622:
617:
612:
607:
602:
597:
581:
576:
571:
566:
550:
545:
540:
535:
530:
525:
1784:
1763:
1738:
512:
1600:
1443:
1405:
1322:
1242:
69:
1739:"All Tcf HMG box transcription factors interact with Groucho-related co-repressors"
1557:
1003:
327:
106:
1427:
93:
1226:
1104:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1086:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1711:
410:
1541:
1389:
1306:
1267:
1018:
DNA binding domain and participates in the regulation of cell cycle genes and
226:
123:
73:
1754:
1465:
1209:
Kim TW, Kim HJ, Lee C, Kim HY, Baek SH, Kim JH, Kwon KS, Kim JR (Apr 2008).
662:
470:
348:
293:
280:
192:
179:
81:
1772:
1729:
1686:
1643:
1592:
1549:
1473:
1435:
1397:
1367:
1348:
1314:
1285:
1234:
1201:
1162:
1516:
1180:
972:
967:
1625:
1525:
956:
807:
788:
1668:
1147:"A gene family of HMG-box transcription factors with homology to TCF-1"
1121:"TCF7L1 transcription factor 7 like 1 [ Homo sapiens (human) ]"
774:
729:
940:
684:
546:
DNA-binding transcription factor activity, RNA polymerase II-specific
1210:
1610:"Dazap2 modulates transcription driven by the Wnt effector TCF-4"
647:
643:
988:
61:
1737:
Brantjes H, Roose J, van De
Wetering M, Clevers H (Apr 2001).
1565:
Graham TA, Weaver C, Mao F, Kimelman D, Xu W (Dec 2000).
317:
1250:
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010).
482:
1481:Barker N, Huls G, Korinek V, Clevers H (Jan 1999).
897:
876:
846:
825:
1060:
1058:
1056:
1039:
1037:
1035:
1014:signaling pathway. The encoded protein contains a
1567:"Crystal structure of a beta-catenin/Tcf complex"
264:
163:
623:regulation of transcription by RNA polymerase II
1145:Castrop J, van Norren K, Clevers H (Feb 1992).
16:Protein-coding gene in the species Homo sapiens
1065:GRCm38: Ensembl release 89: ENSMUSG00000055799
996:T cell factor/lymphoid enhancer factor family
8:
48:, TCF-3, TCF3, transcription factor 7 like 1
1378:International Journal of Colorectal Disease
1044:GRCh38: Ensembl release 89: ENSG00000152284
658:
628:regulation of transcription, DNA-templated
508:
305:
204:
101:
1762:
1719:
1676:
1633:
1582:
1506:
1357:
1347:
1275:
1170:
541:DNA-binding transcription factor activity
1115:
1113:
1031:
18:
269:
230:
225:
168:
127:
122:
7:
987:, also known as TCF7L1, is a human
598:regulation of Wnt signaling pathway
994:This gene encodes a member of the
894:
873:
843:
822:
798:
779:
753:
734:
708:
689:
487:
405:
343:
322:
14:
1700:The American Journal of Pathology
1487:The American Journal of Pathology
633:beta-catenin-TCF complex assembly
998:of transcription factors. These
253:
246:
240:
217:
152:
145:
139:
114:
1012:transforming growth factor beta
618:canonical Wnt signaling pathway
567:transcription regulator complex
471:More reference expression data
1:
1584:10.1016/S0092-8674(00)00192-6
1499:10.1016/S0002-9440(10)65247-9
985:Transcription factor 7-like 1
526:sequence-specific DNA binding
449:tunica media of zone of aorta
238:
137:
1428:10.1016/j.neulet.2006.07.045
613:transcription, DNA-templated
1791:Genes on human chromosome 2
1227:10.1016/j.exger.2007.12.010
1010:and are antagonized by the
391:right lobe of thyroid gland
379:subcutaneous adipose tissue
1817:
1712:10.2353/ajpath.2006.050686
1530:Osteoporosis International
383:left lobe of thyroid gland
1542:10.1007/s00198-009-0931-0
1390:10.1007/s00384-010-0959-9
1336:Cancer Cell International
1307:10.1007/s12015-007-0006-6
1268:10.2119/molmed.2009.00159
1100:"Mouse PubMed Reference:"
1082:"Human PubMed Reference:"
971:
966:
962:
955:
939:
920:
901:
880:
869:
850:
829:
818:
805:
801:
786:
782:
773:
760:
756:
741:
737:
728:
715:
711:
696:
692:
683:
668:
661:
657:
641:
511:
507:
495:
490:
481:
468:
417:
408:
375:Descending thoracic aorta
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1215:Experimental Gerontology
1466:10.3171/2008.9.JNS08551
1454:Journal of Neurosurgery
1016:high mobility group-box
926:Chr 2: 85.13 – 85.31 Mb
425:external carotid artery
421:internal carotid artery
1743:Nucleic Acids Research
1614:Nucleic Acids Research
1349:10.1186/1475-2867-9-28
1151:Nucleic Acids Research
933:Chr 6: 72.6 – 72.77 Mb
603:chromatin organization
1796:Genes mutated in mice
1755:10.1093/nar/29.7.1410
1008:Wnt signaling pathway
1000:transcription factors
608:Wnt signaling pathway
395:right coronary artery
1657:Molecular Psychiatry
1416:Neuroscience Letters
1163:10.1093/nar/20.3.611
531:beta-catenin binding
271:6 C1|6 32.27 cM
232:Chromosome 6 (mouse)
130:Chromosome 2 (human)
1801:Aging-related genes
1669:10.1038/mp.2008.122
1020:cellular senescence
387:canal of the cervix
1626:10.1093/nar/gkp179
1256:Molecular Medicine
763:ENSMUSG00000055799
591:Biological process
560:Cellular component
519:Molecular function
94:TCF7L1 - orthologs
1295:Stem Cell Reviews
1002:are activated by
982:
981:
978:
977:
951:
950:
916:
915:
891:
890:
865:
864:
840:
839:
814:
813:
795:
794:
769:
768:
750:
749:
724:
723:
705:
704:
653:
652:
551:chromatin binding
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
1808:
1776:
1766:
1733:
1723:
1690:
1680:
1647:
1637:
1604:
1586:
1561:
1520:
1510:
1477:
1447:
1409:
1371:
1361:
1351:
1326:
1289:
1279:
1246:
1205:
1184:
1174:
1131:
1130:
1128:
1127:
1117:
1108:
1107:
1096:
1090:
1089:
1078:
1072:
1062:
1051:
1041:
964:
963:
935:
928:
911:
895:
886:
874:
870:RefSeq (protein)
860:
844:
835:
823:
799:
780:
754:
735:
709:
690:
659:
509:
488:
473:
429:genital tubercle
413:
411:Top expressed in
406:
359:popliteal artery
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1816:
1815:
1811:
1810:
1809:
1807:
1806:
1805:
1781:
1780:
1779:
1736:
1693:
1650:
1607:
1564:
1523:
1480:
1450:
1412:
1374:
1329:
1292:
1262:(7–8): 247–53.
1249:
1208:
1196:(21): 5959–62.
1190:Cancer Research
1187:
1144:
1140:
1138:Further reading
1135:
1134:
1125:
1123:
1119:
1118:
1111:
1098:
1097:
1093:
1080:
1079:
1075:
1063:
1054:
1042:
1033:
1028:
973:View/Edit Mouse
968:View/Edit Human
931:
924:
921:Location (UCSC)
907:
903:
882:
856:
852:
831:
744:ENSG00000152284
637:
586:
555:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
371:ascending aorta
369:
365:
363:tibial arteries
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1814:
1812:
1804:
1803:
1798:
1793:
1783:
1782:
1778:
1777:
1734:
1706:(4): 1134–47.
1691:
1648:
1620:(9): 3007–20.
1605:
1562:
1521:
1478:
1448:
1410:
1372:
1327:
1290:
1247:
1206:
1185:
1141:
1139:
1136:
1133:
1132:
1109:
1091:
1073:
1052:
1030:
1029:
1027:
1024:
1006:, mediate the
980:
979:
976:
975:
970:
960:
959:
953:
952:
949:
948:
946:
944:
937:
936:
929:
922:
918:
917:
914:
913:
899:
898:
892:
889:
888:
878:
877:
871:
867:
866:
863:
862:
848:
847:
841:
838:
837:
827:
826:
820:
816:
815:
812:
811:
803:
802:
796:
793:
792:
784:
783:
777:
771:
770:
767:
766:
758:
757:
751:
748:
747:
739:
738:
732:
726:
725:
722:
721:
713:
712:
706:
703:
702:
694:
693:
687:
681:
680:
675:
670:
666:
665:
655:
654:
651:
650:
639:
638:
636:
635:
630:
625:
620:
615:
610:
605:
600:
594:
592:
588:
587:
585:
584:
579:
574:
569:
563:
561:
557:
556:
554:
553:
548:
543:
538:
533:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
453:abdominal wall
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
367:gastric mucosa
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1813:
1802:
1799:
1797:
1794:
1792:
1789:
1788:
1786:
1774:
1770:
1765:
1760:
1756:
1752:
1749:(7): 1410–9.
1748:
1744:
1740:
1735:
1731:
1727:
1722:
1717:
1713:
1709:
1705:
1701:
1697:
1692:
1688:
1684:
1679:
1674:
1670:
1666:
1662:
1658:
1654:
1649:
1645:
1641:
1636:
1631:
1627:
1623:
1619:
1615:
1611:
1606:
1602:
1598:
1594:
1590:
1585:
1580:
1577:(6): 885–96.
1576:
1572:
1568:
1563:
1559:
1555:
1551:
1547:
1543:
1539:
1536:(1): 109–18.
1535:
1531:
1527:
1522:
1518:
1514:
1509:
1504:
1500:
1496:
1492:
1488:
1484:
1479:
1475:
1471:
1467:
1463:
1459:
1455:
1449:
1445:
1441:
1437:
1433:
1429:
1425:
1421:
1417:
1411:
1407:
1403:
1399:
1395:
1391:
1387:
1383:
1379:
1373:
1369:
1365:
1360:
1355:
1350:
1345:
1341:
1337:
1333:
1328:
1324:
1320:
1316:
1312:
1308:
1304:
1300:
1296:
1291:
1287:
1283:
1278:
1273:
1269:
1265:
1261:
1257:
1253:
1248:
1244:
1240:
1236:
1232:
1228:
1224:
1221:(4): 286–95.
1220:
1216:
1212:
1207:
1203:
1199:
1195:
1191:
1186:
1182:
1178:
1173:
1168:
1164:
1160:
1156:
1152:
1148:
1143:
1142:
1137:
1122:
1116:
1114:
1110:
1105:
1101:
1095:
1092:
1087:
1083:
1077:
1074:
1070:
1066:
1061:
1059:
1057:
1053:
1049:
1045:
1040:
1038:
1036:
1032:
1025:
1023:
1021:
1017:
1013:
1009:
1005:
1001:
997:
992:
990:
986:
974:
969:
965:
961:
958:
954:
947:
945:
942:
938:
934:
930:
927:
923:
919:
912:
910:
906:
900:
896:
893:
887:
885:
879:
875:
872:
868:
861:
859:
855:
849:
845:
842:
836:
834:
828:
824:
821:
819:RefSeq (mRNA)
817:
810:
809:
804:
800:
797:
791:
790:
785:
781:
778:
776:
772:
765:
764:
759:
755:
752:
746:
745:
740:
736:
733:
731:
727:
720:
719:
714:
710:
707:
701:
700:
695:
691:
688:
686:
682:
679:
676:
674:
671:
667:
664:
660:
656:
649:
645:
640:
634:
631:
629:
626:
624:
621:
619:
616:
614:
611:
609:
606:
604:
601:
599:
596:
595:
593:
590:
589:
583:
580:
578:
575:
573:
570:
568:
565:
564:
562:
559:
558:
552:
549:
547:
544:
542:
539:
537:
534:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1746:
1742:
1703:
1699:
1663:(4): 351–3.
1660:
1656:
1617:
1613:
1574:
1570:
1533:
1529:
1493:(1): 29–35.
1490:
1486:
1460:(2): 211–8.
1457:
1453:
1422:(3): 211–6.
1419:
1415:
1384:(8): 931–9.
1381:
1377:
1339:
1335:
1298:
1294:
1259:
1255:
1218:
1214:
1193:
1189:
1154:
1150:
1124:. Retrieved
1103:
1094:
1085:
1076:
1004:beta catenin
993:
984:
983:
905:NP_001073290
902:
881:
854:NM_001079822
851:
830:
806:
787:
761:
742:
716:
697:
677:
672:
457:ciliary body
433:vas deferens
333:
326:
53:External IDs
1301:(1): 30–8.
577:nucleoplasm
536:DNA binding
441:ankle joint
292:72,766,237
279:72,603,361
191:85,310,387
178:85,133,392
31:Identifiers
1785:Categories
1157:(3): 611.
1126:2021-05-29
1071:, May 2017
1050:, May 2017
1026:References
437:left colon
337:(ortholog)
74:HomoloGene
909:NP_033358
884:NP_112573
858:NM_009332
833:NM_031283
663:Orthologs
82:GeneCards
1773:11266540
1730:16565489
1687:19308021
1644:19304756
1601:16865193
1593:11136974
1550:19373426
1474:19301967
1444:53251386
1436:17234346
1406:22778766
1398:20532534
1368:19906297
1323:20861838
1315:17873379
1286:20379614
1243:37034259
1235:18258400
1202:11085512
1067:–
1046:–
957:Wikidata
642:Sources:
445:epiblast
1721:1606554
1678:2694406
1635:2685103
1558:8813712
1517:9916915
1508:1853446
1359:2779787
1277:2896464
1181:1741298
1069:Ensembl
1048:Ensembl
775:UniProt
730:Ensembl
669:Species
648:QuickGO
582:cytosol
572:nucleus
312:pattern
70:1202876
38:Aliases
1771:
1761:
1728:
1718:
1685:
1675:
1642:
1632:
1599:
1591:
1556:
1548:
1515:
1505:
1472:
1442:
1434:
1404:
1396:
1366:
1356:
1342:: 28.
1321:
1313:
1284:
1274:
1241:
1233:
1200:
1179:
1172:310434
1169:
943:search
941:PubMed
808:Q9Z1J1
789:Q9HCS4
685:Entrez
483:BioGPS
170:2p11.2
86:TCF7L1
62:604652
45:TCF7L1
22:TCF7L1
1764:31284
1597:S2CID
1554:S2CID
1440:S2CID
1402:S2CID
1319:S2CID
1239:S2CID
718:21415
699:83439
678:Mouse
673:Human
644:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
1769:PMID
1726:PMID
1683:PMID
1640:PMID
1589:PMID
1571:Cell
1546:PMID
1513:PMID
1470:PMID
1432:PMID
1394:PMID
1364:PMID
1311:PMID
1282:PMID
1231:PMID
1198:PMID
1177:PMID
989:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
78:7563
58:OMIM
1759:PMC
1751:doi
1716:PMC
1708:doi
1704:168
1673:PMC
1665:doi
1630:PMC
1622:doi
1579:doi
1575:103
1538:doi
1503:PMC
1495:doi
1491:154
1462:doi
1458:111
1424:doi
1420:412
1386:doi
1354:PMC
1344:doi
1303:doi
1272:PMC
1264:doi
1223:doi
1167:PMC
1159:doi
491:n/a
288:End
187:End
90:OMA
66:MGI
1787::
1767:.
1757:.
1747:29
1745:.
1741:.
1724:.
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1022:.
991:.
646:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
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72:;
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64:;
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