Knowledge (XXG)

TDBzcholine

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TDBzcholine is able to bind to the nicotinic acetylcholine receptor. Once TDBzcholine is bound to the receptor, TDBzcholine can be activated by exposing the sample to
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radical that can react with amino acid residues in the receptor and become covalently bound to the receptor.
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InChI=1S/C14H17F3N3O2/c1-20(2,3)8-9-22-12(21)10-4-6-11(7-5-10)13(18-19-13)14(15,16)17/h4-7H,8-9H2,1-3H3/q+1
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Except where otherwise noted, data are given for materials in their
88: 78: 388: 316:light. This led to formation of a highly reactive 133: 64: 408: 8: 201:C(C)(C)CCOC(C1=CC=C(C2(C(F)(F)F)N=N2)C=C1)=O 415: 401: 108: 18: 153: 341: 198: 173: 354:Biochemical Pharmacology Lecture Notes 180:Key: IQGNIBHYFCIEEE-UHFFFAOYSA-N 7: 369: 367: 124: 387:. You can help Knowledge (XXG) by 14: 454:Nicotinic acetylcholine receptors 350:"Pharmacology of cell excitation" 16:Diazirine analog of acetylcholine 371: 302:nicotinic acetylcholine receptor 240: 234: 228: 25: 274:(at 25 °C , 100 kPa). 300:that can be used to label the 246: 222: 1: 475: 366: 449:Trifluoromethyl compounds 268: 209: 189: 164: 48: 38: 33: 24: 383:-related article is a 330:Photoaffinity labeling 308:Mechanism of action 264: g·mol 21: 459:Pharmacology stubs 278:Infobox references 19: 396: 395: 286:Chemical compound 284: 283: 90:Interactive image 466: 417: 410: 403: 375: 368: 358: 357: 346: 263: 248: 242: 236: 230: 224: 217:Chemical formula 157: 137: 126: 112: 92: 68: 43:4-benzoylcholine 29: 22: 474: 473: 469: 468: 467: 465: 464: 463: 444:Benzoate esters 424: 423: 422: 421: 364: 362: 361: 348: 347: 343: 338: 326: 310: 287: 280: 275: 261: 251: 245: 239: 233: 227: 219: 205: 202: 197: 196: 185: 182: 181: 178: 172: 171: 160: 140: 127: 115: 95: 82: 71: 58: 44: 17: 12: 11: 5: 472: 470: 462: 461: 456: 451: 446: 441: 439:Choline esters 436: 426: 425: 420: 419: 412: 405: 397: 394: 393: 376: 360: 359: 340: 339: 337: 334: 333: 332: 325: 322: 309: 306: 285: 282: 281: 276: 272:standard state 269: 266: 265: 259: 253: 252: 249: 243: 237: 231: 225: 220: 215: 212: 211: 207: 206: 204: 203: 200: 192: 191: 190: 187: 186: 184: 183: 179: 176: 175: 167: 166: 165: 162: 161: 159: 158: 150: 148: 142: 141: 139: 138: 130: 128: 120: 117: 116: 114: 113: 105: 103: 97: 96: 94: 93: 85: 83: 76: 73: 72: 70: 69: 61: 59: 54: 51: 50: 46: 45: 42: 36: 35: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 471: 460: 457: 455: 452: 450: 447: 445: 442: 440: 437: 435: 432: 431: 429: 418: 413: 411: 406: 404: 399: 398: 392: 390: 386: 382: 377: 374: 370: 365: 355: 351: 345: 342: 335: 331: 328: 327: 323: 321: 319: 315: 307: 305: 303: 299: 298:acetylcholine 295: 291: 279: 273: 267: 260: 258: 255: 254: 221: 218: 214: 213: 208: 199: 195: 188: 174: 170: 163: 156: 152: 151: 149: 147: 144: 143: 136: 132: 131: 129: 123: 119: 118: 111: 107: 106: 104: 102: 99: 98: 91: 87: 86: 84: 80: 75: 74: 67: 63: 62: 60: 57: 53: 52: 47: 41: 37: 32: 28: 23: 389:expanding it 381:pharmacology 378: 363: 353: 344: 311: 289: 288: 49:Identifiers 20:TDBzcholine 290:TDBzcholine 210:Properties 66:496972-30-6 434:Diazirines 428:Categories 336:References 296:analog of 257:Molar mass 155:NTU9QE4VZL 101:ChemSpider 77:3D model ( 56:CAS Number 40:IUPAC name 294:diazirine 110:103875307 324:See also 135:90716102 318:carbene 262:316.304 122:PubChem 194:SMILES 34:Names 379:This 292:is a 169:InChI 79:JSmol 385:stub 146:UNII 125:CID 430:: 352:. 314:UV 304:. 232:17 226:14 416:e 409:t 402:v 391:. 356:. 250:2 247:O 244:3 241:N 238:3 235:F 229:H 223:C 81:)

Index


IUPAC name
CAS Number
496972-30-6
JSmol
Interactive image
ChemSpider
103875307
PubChem
90716102
UNII
NTU9QE4VZL
InChI
SMILES
Chemical formula
Molar mass
standard state
Infobox references
diazirine
acetylcholine
nicotinic acetylcholine receptor
UV
carbene
Photoaffinity labeling
"Pharmacology of cell excitation"
Stub icon
pharmacology
stub
expanding it
v

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