380:
357:
25:
2455:
254:
279:
2470:
645:
638:
631:
386:
285:
99:
125:
2454:
3572:
2375:
Mori T, Kawara S, Shinozaki M, et al. (1999). "Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model".
2338:
Fromigué O, Marie PJ, Lomri A (1998). "Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation".
2029:
Webb NR, Madisen L, Rose TM, Purchio AF (1989). "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing".
2223:"The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands"
2087:
Barton DE, Foellmer BE, Du J, et al. (1989). "Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family".
2469:
2000:
Bodmer S, Podlisny MB, Selkoe DJ, et al. (1990). "Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of
Alzheimer's disease".
3565:
393:
292:
54:
3558:
3049:
2510:
2810:
2531:
1926:
Schlunegger MP, Grütter MG (1992). "An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2".
1403:
1384:
215:
2947:
2941:
2936:
2926:
2921:
2916:
2911:
2906:
2188:"Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction"
3082:
1971:
Noma T, Glick AB, Geiser AG, et al. (1992). "Molecular cloning and structure of the human transforming growth factor-beta 2 gene promoter".
5130:
3307:
2110:"Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family"
5247:
2434:
5229:
5270:
3508:
3503:
3498:
2763:
1811:
2613:
2388:
2351:
1619:
379:
3490:
2855:
2297:"Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites"
1626:
3110:
76:
356:
2503:
5216:
5195:
5049:
4475:
4119:
3815:
3670:
3396:
3325:
2995:
2718:
2553:
3457:
3125:
2258:"Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta"
5212:
2463:: AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
278:
253:
122:
4881:
4717:
4582:
4465:
4367:
4293:
4105:
3996:
3660:
3005:
2678:
2671:
2666:
2661:
2656:
2058:
Madisen L, Webb NR, Rose TM, et al. (1988). "Transforming growth factor-beta 2: cDNA cloning and sequence analysis".
5191:
5007:
4917:
4853:
4673:
4550:
4438:
4249:
3895:
3595:
3581:
3384:
3379:
3075:
2651:
2646:
2641:
2636:
2631:
2626:
195:
37:
3513:
3275:
2496:
392:
291:
47:
41:
33:
4849:
4669:
4546:
4245:
3891:
3784:
3645:
3369:
3352:
3317:
3154:
2957:
2621:
1768:
Wick W, Platten M, Weller M (2002). "Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta".
385:
284:
4993:
3886:
3774:
2740:
2523:
2427:
58:
3539:
3099:
2838:
2783:
2767:
1448:
203:
5280:
3518:
3302:
3068:
1429:
1686:
2420:
1935:
1898:
1715:
1259:
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
1254:
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
267:
182:
5140:
3534:
2890:
2575:
1598:
1573:
1547:
1522:
4334:
3945:
3848:
5090:
4965:
3728:
3587:
2965:
2754:
2400:
2363:
1959:
1793:
227:
4922:
4765:
4604:
4319:
1602:
1577:
1543:
1518:
4523:
4424:
4212:
4207:
4177:
4172:
4072:
5275:
5115:
4192:
3655:
2985:
2545:
2392:
2355:
2326:
2283:
2244:
2209:
2174:
2139:
2096:
2075:
2046:
2017:
1988:
1951:
1914:
1873:
1830:
1785:
1756:
1724:
644:
637:
630:
175:
115:
4414:
4339:
4162:
4062:
3950:
3853:
3703:
1887:"Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily"
5135:
5125:
4217:
4167:
3858:
3708:
3010:
3000:
2759:
2541:
2478:: CRYSTAL STRUCTURE OF TRANSFORMING GROWTH FACTOR-BETA2: AN UNUSUAL FOLD FOR THE SUPERFAMILY
2384:
2347:
2316:
2308:
2273:
2265:
2234:
2199:
2164:
2129:
2121:
2067:
2038:
2009:
1980:
1943:
1906:
1863:
1855:
1820:
1777:
1748:
472:
403:
347:
302:
4518:
4329:
3940:
3843:
3838:
223:
4946:
4876:
4871:
4789:
4712:
4707:
4577:
4572:
4395:
4288:
4283:
4043:
3930:
3925:
3810:
3436:
3431:
3289:
2990:
1694:-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin
447:
2488:
1939:
1902:
3550:
2894:
2519:
2321:
2296:
2278:
2257:
2204:
2187:
2125:
98:
2169:
2152:
2134:
2109:
1868:
1843:
1752:
1318:
1313:
1308:
1303:
1298:
1293:
1288:
1283:
1278:
1273:
1268:
1263:
1258:
1253:
1248:
1243:
1238:
1233:
1228:
1223:
1218:
1213:
1208:
1203:
1198:
1193:
1188:
1183:
1178:
1173:
1168:
1163:
1158:
1153:
1148:
1143:
1138:
1133:
1128:
1123:
1118:
1113:
1108:
1103:
1098:
1093:
1088:
1083:
1078:
1073:
1068:
1063:
1058:
1053:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1013:
1008:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
838:
833:
828:
823:
818:
813:
808:
803:
798:
793:
777:
772:
767:
762:
757:
752:
747:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
5264:
5100:
3693:
3091:
2013:
1700:
1697:
673:
2404:
2367:
1797:
5120:
4503:
4498:
4187:
4147:
4142:
3718:
1963:
1691:
465:
244:
207:
231:
5252:
National Center for
Biotechnology Information, U.S. National Library of Medicine
5234:
National Center for
Biotechnology Information, U.S. National Library of Medicine
5110:
4808:
4508:
4152:
3020:
2980:
1704:
548:
5150:
5061:
5053:
4843:
4663:
4487:
4479:
4182:
4131:
4123:
3990:
3827:
3819:
3768:
3682:
3674:
3634:
3340:
3330:
2876:
2568:
2558:
2153:"Complete amino acid sequence of human transforming growth factor type beta 2"
1984:
1781:
364:
261:
211:
2042:
5043:
5039:
5030:
4940:
4936:
4907:
4839:
4835:
4783:
4779:
4755:
4659:
4655:
4622:
4618:
4460:
4419:
4202:
4100:
4067:
4037:
4033:
4014:
3986:
3982:
3779:
3764:
3760:
3640:
3630:
3626:
3441:
3297:
2713:
1910:
1348:
608:
486:
431:
418:
330:
317:
219:
5016:
4447:
2396:
2239:
2222:
1877:
1834:
1789:
2389:
10.1002/(SICI)1097-4652(199910)181:1<153::AID-JCP16>3.0.CO;2-K
2359:
2352:
10.1002/(SICI)1097-4644(19980315)68:4<411::AID-JCB2>3.0.CO;2-T
2330:
2312:
2287:
2248:
2213:
2178:
2143:
2100:
2079:
2050:
2021:
1992:
1955:
1918:
1760:
1666:
1661:
5167:
3251:
2071:
1682:
1650:
1493:
1474:
1825:
1806:
1739:
Clark DA, Coker R (1998). "Transforming growth factor-beta (TGF-beta)".
5105:
5095:
5035:
4932:
4831:
4775:
4651:
4614:
4029:
3978:
3756:
3622:
3426:
3365:
2975:
2970:
1460:
1415:
1239:
regulation of apoptotic process involved in outflow tract morphogenesis
2269:
1004:
positive regulation of pathway-restricted SMAD protein phosphorylation
152:
148:
144:
5156:
4954:
4950:
4818:
4797:
4793:
4633:
4403:
4399:
4197:
4051:
4047:
3033:
2932:
2902:
2848:
2843:
2820:
2815:
2805:
2798:
2793:
1947:
1859:
1844:"Epithelial-mesenchymal transition and its implications for fibrosis"
1711:
1708:
1634:
1370:
1886:
4232:
3873:
1289:
positive regulation of pri-miRNA transcription by RNA polymerase II
5085:
5017:
4975:
4912:
4760:
4749:
4745:
4701:
4697:
4693:
4566:
4534:
4533:
4469:
4448:
4385:
4379:
4313:
4277:
4273:
4269:
4113:
4109:
4087:
4019:
4008:
3919:
3915:
3804:
3800:
3649:
3480:
3475:
3470:
3465:
3421:
3416:
3411:
3406:
3270:
3265:
3260:
3236:
3230:
3224:
3218:
3198:
3194:
3185:
3181:
3172:
3168:
3028:
2860:
2788:
2733:
2728:
2723:
2602:
2595:
2590:
2585:
1685:
that performs many cellular functions and has a vital role during
3060:
1333:
1329:
4901:
4897:
4893:
4889:
4885:
4865:
4861:
4857:
4741:
4737:
4733:
4729:
4725:
4721:
4689:
4685:
4681:
4677:
4598:
4594:
4590:
4586:
4562:
4558:
4554:
4375:
4371:
4349:
4309:
4305:
4301:
4297:
4265:
4261:
4257:
4253:
4227:
4082:
4004:
4000:
3960:
3911:
3907:
3903:
3899:
3868:
3796:
3792:
3788:
3738:
3664:
3604:
3190:
3177:
3164:
3142:
3138:
3134:
3129:
3121:
2708:
2703:
2698:
2693:
2688:
2683:
2580:
1719:
199:
3554:
3064:
2492:
2416:
2108:
de Martin R, Haendler B, Hofer-Warbinek R, et al. (1988).
653:
4976:
2412:
2186:
Philip A, Bostedt L, Stigbrand T, O'Connor-McCourt MD (1994).
1044:
positive regulation of phosphatidylinositol 3-kinase signaling
18:
2256:
Hildebrand A, Romarís M, Rasmussen LM, et al. (1994).
1714:. There are two named isoforms of this protein, created by
954:
positive regulation of epithelial to mesenchymal transition
2295:
López-Casillas F, Payne HM, Andres JL, Massagué J (1994).
874:
transforming growth factor beta receptor signaling pathway
864:
positive regulation of cell adhesion mediated by integrin
799:
regulation of transforming growth factor beta2 production
697:
type III transforming growth factor beta receptor binding
687:
type II transforming growth factor beta receptor binding
455:
4980:
3582:
4350:
4228:
4083:
3961:
3869:
3739:
3609:
3605:
1194:
negative regulation of Ras protein signal transduction
859:
negative regulation of macrophage cytokine production
620:
186:, TGF-beta2, transforming growth factor beta 2, G-TSF
1039:
positive regulation of cell population proliferation
884:
positive regulation of stress-activated MAPK cascade
879:
negative regulation of cell population proliferation
854:
negative regulation of alkaline phosphatase activity
844:
negative regulation of epithelial cell proliferation
819:
positive regulation of integrin biosynthetic process
5075:
5015:
5006:
4974:
4817:
4632:
4532:
4446:
4437:
4348:
4226:
4081:
3959:
3867:
3737:
3603:
3594:
3527:
3489:
3456:
3393:
3362:
3351:
3316:
3288:
3246:
3207:
3151:
3107:
3098:
3042:
3019:
2956:
2889:
2869:
2831:
2776:
2753:
2611:
2539:
2530:
1591:
1566:
1536:
1511:
5208:
5206:
5204:
5187:
5185:
5183:
4354:
3965:
3743:
2221:Lin HY, Moustakas A, Knaus P, et al. (1995).
1294:embryo development ending in birth or egg hatching
929:positive regulation of cardioblast differentiation
402:
301:
4819:
4634:
1703:protein. It is known to suppress the effects of
904:positive regulation of epithelial cell migration
707:transforming growth factor beta receptor binding
46:but its sources remain unclear because it lacks
4638:
1219:pathway-restricted SMAD protein phosphorylation
974:regulation of complement-dependent cytotoxicity
834:positive regulation of neuron apoptotic process
16:Protein-coding gene in the species Homo sapiens
5213:GRCm38: Ensembl release 89: ENSMUSG00000039239
1885:Daopin S, Piez KA, Ogawa Y, Davies DR (1992).
1279:positive regulation of Notch signaling pathway
1134:ventricular trabecula myocardium morphogenesis
3566:
3076:
2504:
2428:
8:
1807:"Chronic liver injury, TGF-beta, and cancer"
1064:cardiac epithelial to mesenchymal transition
5192:GRCh38: Ensembl release 89: ENSG00000092969
1309:regulation of cell population proliferation
5012:
4443:
3600:
3573:
3559:
3551:
3359:
3104:
3083:
3069:
3061:
2773:
2536:
2511:
2497:
2489:
2435:
2421:
2413:
1679:Transforming growth factor-beta 2 (TGF-β2)
1344:
669:
443:
342:
239:
133:
2320:
2277:
2238:
2203:
2168:
2151:Marquardt H, Lioubin MN, Ikeda T (1987).
2133:
1867:
1824:
1264:regulation of signaling receptor activity
77:Learn how and when to remove this message
1244:substantia propria of cornea development
979:positive regulation of protein secretion
964:positive regulation of timing of catagen
829:positive regulation of heart contraction
778:collagen-containing extracellular matrix
5179:
2450:
1269:negative regulation of gene expression
1029:negative regulation of immune response
969:positive regulation of immune response
88:
1812:Experimental & Molecular Medicine
1129:cardiac right ventricle morphogenesis
1054:activation of protein kinase activity
989:embryonic digestive tract development
894:extrinsic apoptotic signaling pathway
407:
368:
363:
306:
265:
260:
7:
1234:pharyngeal arch artery morphogenesis
1114:atrioventricular valve morphogenesis
1059:positive regulation of cell division
984:epithelial to mesenchymal transition
1274:negative regulation of angiogenesis
1249:cranial skeletal system development
944:positive regulation of ossification
732:protein heterodimerization activity
5083:Endogenous antagonists/inhibitors:
2205:10.1111/j.1432-1033.1994.tb18781.x
2126:10.1002/j.1460-2075.1987.tb02700.x
1588:
1563:
1533:
1508:
1484:
1465:
1439:
1420:
1394:
1375:
1144:atrial septum primum morphogenesis
1099:outflow tract septum morphogenesis
924:negative regulation of cell growth
914:positive regulation of cell growth
625:
543:
481:
460:
14:
1681:is a secreted protein known as a
1189:positive regulation of cell cycle
1124:endocardial cushion morphogenesis
949:cardiac muscle cell proliferation
717:protein homodimerization activity
2468:
2453:
1284:SMAD protein signal transduction
1224:ventricular septum morphogenesis
643:
636:
629:
391:
384:
378:
355:
290:
283:
277:
252:
97:
23:
3397:Relaxin family peptide hormones
2532:TGF beta superfamily of ligands
1314:regulation of apoptotic process
1299:regulation of timing of catagen
1104:membranous septum morphogenesis
889:cell-cell junction organization
3859:ML-347 (LDN-193719, VU0469381)
3709:ML-347 (LDN-193719, VU0469381)
2679:Growth differentiation factors
1842:Kalluri R, Neilson EG (2004).
654:More reference expression data
609:More reference expression data
1:
2170:10.1016/S0021-9258(18)45325-2
2002:Biochem. Biophys. Res. Commun
1753:10.1016/S1357-2725(97)00128-3
1184:dopamine biosynthetic process
1179:ascending aorta morphogenesis
1119:pulmonary valve morphogenesis
869:cell population proliferation
376:
275:
2264:. 302. ( Pt 2) (2): 527–34.
2014:10.1016/0006-291X(90)91229-L
1304:secondary palate development
1169:embryonic limb morphogenesis
1019:salivary gland morphogenesis
899:collagen fibril organization
758:platelet alpha granule lumen
587:Epithelium of choroid plexus
5271:Genes on human chromosome 1
4198:RepSox (E-616452, SJN-2511)
2622:Bone morphogenetic proteins
1229:atrial septum morphogenesis
1174:hair follicle morphogenesis
1079:skeletal system development
814:cardioblast differentiation
5297:
3370:Insulin-like growth factor
1741:Int. J. Biochem. Cell Biol
1319:regulation of MAPK cascade
1199:somatic stem cell division
1139:endocardial cushion fusion
692:signaling receptor binding
5248:"Mouse PubMed Reference:"
5230:"Human PubMed Reference:"
4188:Galunisertib (LY-2157299)
2448:
1985:10.3109/08977199109043910
1665:
1660:
1656:
1649:
1633:
1627:Chr 1: 186.35 – 186.44 Mb
1620:Chr 1: 218.35 – 218.44 Mb
1614:
1595:
1570:
1559:
1540:
1515:
1504:
1491:
1487:
1472:
1468:
1459:
1446:
1442:
1427:
1423:
1414:
1401:
1397:
1382:
1378:
1369:
1354:
1347:
1343:
1327:
1149:neural retina development
1109:heart valve morphogenesis
1094:hair follicle development
672:
668:
651:
628:
619:
606:
555:
546:
493:
484:
454:
446:
442:
425:
412:
375:
354:
345:
341:
324:
311:
274:
251:
242:
238:
193:
190:
180:
173:
168:
141:
136:
119:
114:
109:
105:
96:
91:
5136:Thrombospondin 1 (THBS1)
4918:Osteogenin (BMP3, BMP3A)
2839:Activin type 2 receptors
2784:Activin type 1 receptors
2043:10.1089/dna.1.1988.7.493
804:response to progesterone
509:tendon of biceps brachii
32:This article includes a
3210:FGF homologous factors:
1911:10.1126/science.1631557
1782:10.1023/A:1012209518843
824:protein phosphorylation
583:internal carotid artery
575:external carotid artery
61:more precise citations.
4335:Dorsomorphin (BML-275)
3946:Dorsomorphin (BML-275)
3849:Dorsomorphin (BML-275)
2741:Anti-müllerian hormone
2524:TGFβ signaling pathway
2240:10.1074/jbc.270.6.2747
1159:male gonad development
1014:platelet degranulation
849:uterine wall breakdown
712:growth factor activity
2313:10.1083/jcb.124.4.557
1687:embryonic development
1209:inner ear development
1069:BMP signaling pathway
1024:generation of neurons
909:neutrophil chemotaxis
517:minor salivary glands
3585:receptor superfamily
3491:Vascular endothelial
2072:10.1089/dna.1988.7.1
1716:alternative splicing
1689:(alternative names:
934:glial cell migration
919:response to wounding
753:extracellular matrix
748:extracellular region
722:amyloid-beta binding
533:smooth muscle tissue
409:1 H5|1 89.95 cM
370:Chromosome 1 (mouse)
268:Chromosome 1 (human)
137:List of PDB id codes
110:Available structures
5153:(against myostatin)
2576:Activin and inhibin
1940:1992Natur.358..430S
1903:1992Sci...257..369D
1826:10.1038/emm.2001.31
1805:Bissell DM (2002).
1089:neural tube closure
1009:heart morphogenesis
999:cell-cell signaling
994:response to hypoxia
763:extracellular space
595:submandibular gland
529:islet of Langerhans
505:germinal epithelium
5159:(against endoglin)
4516:Kinase inhibitors:
4412:Kinase inhibitors:
4327:Kinase inhibitors:
4160:Kinase inhibitors:
4060:Kinase inhibitors:
3938:Kinase inhibitors:
3836:Kinase inhibitors:
3701:Kinase inhibitors:
2755:TGF beta receptors
1449:ENSMUSG00000039239
1214:uterus development
1204:neuron development
1084:kidney development
1034:cell morphogenesis
787:Biological process
773:neuronal cell body
741:Cellular component
680:Molecular function
559:epithelium of lens
34:list of references
5176:
5175:
5071:
5070:
5002:
5001:
4433:
4432:
3726:Other inhibitors:
3548:
3547:
3452:
3451:
3284:
3283:
3058:
3057:
2958:Ligand inhibitors
2885:
2884:
2749:
2748:
2486:
2485:
2270:10.1042/bj3020527
1676:
1675:
1672:
1671:
1645:
1644:
1610:
1609:
1585:
1584:
1555:
1554:
1530:
1529:
1500:
1499:
1481:
1480:
1455:
1454:
1436:
1435:
1410:
1409:
1391:
1390:
1339:
1338:
1154:heart development
702:cytokine activity
664:
663:
660:
659:
615:
614:
602:
601:
540:
539:
438:
437:
337:
336:
232:TGFB2 - orthologs
164:
163:
160:
159:
120:Ortholog search:
87:
86:
79:
5288:
5256:
5255:
5244:
5238:
5237:
5226:
5220:
5210:
5199:
5189:
5019:
5013:
4982:
4978:
4963:Decoy receptors:
4908:Myostatin (GDF8)
4821:
4806:Decoy receptors:
4756:Myostatin (GDF8)
4640:
4636:
4536:
4450:
4444:
4356:
4352:
4234:
4230:
4089:
4085:
4015:Myostatin (GDF8)
3967:
3963:
3875:
3871:
3745:
3741:
3716:Decoy receptors:
3611:
3607:
3601:
3584:
3575:
3568:
3561:
3552:
3458:Platelet-derived
3400:
3373:
3360:
3254:
3212:
3158:
3115:
3105:
3085:
3078:
3071:
3062:
2774:
2537:
2513:
2506:
2499:
2490:
2472:
2457:
2437:
2430:
2423:
2414:
2408:
2377:J. Cell. Physiol
2371:
2340:J. Cell. Biochem
2334:
2324:
2291:
2281:
2252:
2242:
2217:
2207:
2182:
2172:
2163:(25): 12127–31.
2147:
2137:
2104:
2083:
2054:
2025:
1996:
1967:
1948:10.1038/358430a0
1922:
1897:(5068): 369–73.
1881:
1871:
1860:10.1172/JCI20530
1838:
1828:
1801:
1764:
1658:
1657:
1629:
1622:
1605:
1589:
1580:
1564:
1560:RefSeq (protein)
1550:
1534:
1525:
1509:
1485:
1466:
1440:
1421:
1395:
1376:
1345:
1074:cell development
670:
656:
647:
640:
633:
626:
611:
591:semi-lunar valve
579:secondary oocyte
551:
549:Top expressed in
544:
521:ventricular zone
501:cartilage tissue
489:
487:Top expressed in
482:
461:
444:
434:
421:
410:
395:
388:
382:
371:
359:
343:
333:
320:
309:
294:
287:
281:
270:
256:
240:
234:
185:
178:
155:
134:
128:
107:
106:
101:
89:
82:
75:
71:
68:
62:
57:this article by
48:inline citations
27:
26:
19:
5296:
5295:
5291:
5290:
5289:
5287:
5286:
5285:
5261:
5260:
5259:
5246:
5245:
5241:
5228:
5227:
5223:
5211:
5202:
5190:
5181:
5177:
5172:
5091:Cerberus (CER1)
5067:
4998:
4970:
4877:Eptotermin alfa
4872:Dibotermin alfa
4813:
4713:Eptotermin alfa
4708:Dibotermin alfa
4628:
4578:Eptotermin alfa
4573:Dibotermin alfa
4528:
4429:
4344:
4289:Eptotermin alfa
4284:Dibotermin alfa
4222:
4077:
3955:
3931:Eptotermin alfa
3926:Dibotermin alfa
3863:
3811:Eptotermin alfa
3733:
3590:
3579:
3549:
3544:
3523:
3485:
3448:
3394:
3389:
3363:
3354:
3347:
3312:
3290:EGF-like domain
3280:
3247:
3242:
3208:
3203:
3152:
3147:
3108:
3094:
3089:
3059:
3054:
3038:
3015:
2952:
2881:
2865:
2827:
2757:
2745:
2607:
2554:TGF beta family
2526:
2517:
2487:
2482:
2479:
2473:
2464:
2458:
2444:
2441:
2411:
2374:
2337:
2294:
2255:
2220:
2192:Eur. J. Biochem
2185:
2150:
2107:
2086:
2057:
2028:
1999:
1970:
1934:(6385): 430–4.
1925:
1884:
1854:(12): 1776–84.
1848:J. Clin. Invest
1841:
1804:
1767:
1738:
1734:
1732:Further reading
1667:View/Edit Mouse
1662:View/Edit Human
1625:
1618:
1615:Location (UCSC)
1601:
1597:
1576:
1572:
1546:
1542:
1521:
1517:
1430:ENSG00000092969
1323:
794:eye development
782:
736:
727:protein binding
652:
642:
641:
635:
634:
607:
598:
593:
589:
585:
581:
577:
573:
569:
565:
561:
547:
536:
531:
527:
523:
519:
515:
511:
507:
503:
499:
497:Achilles tendon
485:
429:
416:
408:
398:
397:
396:
389:
369:
346:Gene location (
328:
315:
307:
297:
296:
295:
288:
266:
243:Gene location (
194:
181:
174:
143:
121:
83:
72:
66:
63:
52:
38:related reading
28:
24:
17:
12:
11:
5:
5294:
5292:
5284:
5283:
5278:
5273:
5263:
5262:
5258:
5257:
5239:
5221:
5200:
5178:
5174:
5173:
5171:
5170:
5161:
5160:
5154:
5144:
5143:
5138:
5133:
5128:
5123:
5118:
5113:
5108:
5103:
5098:
5093:
5088:
5079:
5077:
5073:
5072:
5069:
5068:
5066:
5065:
5047:
5033:
5024:
5022:
5010:
5004:
5003:
5000:
4999:
4997:
4996:
4987:
4985:
4972:
4971:
4969:
4968:
4959:
4958:
4944:
4926:
4925:
4920:
4915:
4910:
4905:
4879:
4874:
4869:
4847:
4825:
4823:
4815:
4814:
4812:
4811:
4802:
4801:
4787:
4769:
4768:
4763:
4758:
4753:
4715:
4710:
4705:
4667:
4645:
4643:
4630:
4629:
4627:
4626:
4608:
4607:
4602:
4580:
4575:
4570:
4540:
4538:
4530:
4529:
4527:
4526:
4521:
4512:
4511:
4506:
4501:
4492:
4491:
4473:
4463:
4454:
4452:
4441:
4435:
4434:
4431:
4430:
4428:
4427:
4422:
4417:
4408:
4407:
4389:
4388:
4383:
4361:
4359:
4346:
4345:
4343:
4342:
4337:
4332:
4323:
4322:
4317:
4291:
4286:
4281:
4239:
4237:
4224:
4223:
4221:
4220:
4215:
4210:
4205:
4200:
4195:
4190:
4185:
4180:
4175:
4170:
4165:
4156:
4155:
4150:
4145:
4136:
4135:
4117:
4103:
4094:
4092:
4079:
4078:
4076:
4075:
4070:
4065:
4056:
4055:
4041:
4023:
4022:
4017:
4012:
3994:
3972:
3970:
3957:
3956:
3954:
3953:
3948:
3943:
3934:
3933:
3928:
3923:
3889:
3880:
3878:
3865:
3864:
3862:
3861:
3856:
3851:
3846:
3841:
3832:
3831:
3813:
3808:
3782:
3777:
3772:
3750:
3748:
3735:
3734:
3732:
3731:
3722:
3721:
3712:
3711:
3706:
3697:
3696:
3687:
3686:
3668:
3658:
3653:
3643:
3638:
3616:
3614:
3598:
3592:
3591:
3580:
3578:
3577:
3570:
3563:
3555:
3546:
3545:
3543:
3542:
3537:
3531:
3529:
3525:
3524:
3522:
3521:
3516:
3511:
3506:
3501:
3495:
3493:
3487:
3486:
3484:
3483:
3478:
3473:
3468:
3462:
3460:
3454:
3453:
3450:
3449:
3447:
3446:
3445:
3444:
3439:
3434:
3424:
3419:
3414:
3409:
3403:
3401:
3391:
3390:
3388:
3387:
3382:
3376:
3374:
3357:
3355:Relaxin family
3349:
3348:
3346:
3345:
3344:
3343:
3338:
3333:
3322:
3320:
3314:
3313:
3311:
3310:
3305:
3300:
3294:
3292:
3286:
3285:
3282:
3281:
3279:
3278:
3273:
3268:
3263:
3257:
3255:
3244:
3243:
3241:
3240:
3234:
3228:
3222:
3215:
3213:
3205:
3204:
3202:
3201:
3188:
3175:
3161:
3159:
3149:
3148:
3146:
3145:
3132:
3118:
3116:
3102:
3096:
3095:
3092:Growth factors
3090:
3088:
3087:
3080:
3073:
3065:
3056:
3055:
3053:
3052:
3046:
3044:
3040:
3039:
3037:
3036:
3031:
3025:
3023:
3017:
3016:
3014:
3013:
3008:
3003:
2998:
2993:
2988:
2983:
2978:
2973:
2968:
2962:
2960:
2954:
2953:
2951:
2950:
2945:
2939:
2930:
2924:
2919:
2914:
2909:
2899:
2897:
2887:
2886:
2883:
2882:
2880:
2879:
2873:
2871:
2867:
2866:
2864:
2863:
2858:
2853:
2852:
2851:
2846:
2835:
2833:
2829:
2828:
2826:
2825:
2824:
2823:
2818:
2808:
2803:
2802:
2801:
2796:
2791:
2780:
2778:
2771:
2751:
2750:
2747:
2746:
2744:
2743:
2738:
2737:
2736:
2731:
2726:
2721:
2716:
2714:Myostatin/GDF8
2711:
2706:
2701:
2696:
2691:
2686:
2676:
2675:
2674:
2669:
2664:
2659:
2654:
2649:
2644:
2639:
2634:
2629:
2618:
2616:
2609:
2608:
2606:
2605:
2600:
2599:
2598:
2593:
2588:
2583:
2573:
2572:
2571:
2566:
2561:
2550:
2548:
2534:
2528:
2527:
2520:Cell signaling
2518:
2516:
2515:
2508:
2501:
2493:
2484:
2483:
2481:
2480:
2474:
2467:
2465:
2459:
2452:
2449:
2446:
2445:
2442:
2440:
2439:
2432:
2425:
2417:
2410:
2409:
2372:
2335:
2292:
2253:
2233:(6): 2747–54.
2218:
2183:
2148:
2120:(12): 3673–7.
2105:
2084:
2055:
2026:
1997:
1973:Growth Factors
1968:
1923:
1882:
1839:
1802:
1765:
1735:
1733:
1730:
1674:
1673:
1670:
1669:
1664:
1654:
1653:
1647:
1646:
1643:
1642:
1640:
1638:
1631:
1630:
1623:
1616:
1612:
1611:
1608:
1607:
1593:
1592:
1586:
1583:
1582:
1568:
1567:
1561:
1557:
1556:
1553:
1552:
1538:
1537:
1531:
1528:
1527:
1513:
1512:
1506:
1502:
1501:
1498:
1497:
1489:
1488:
1482:
1479:
1478:
1470:
1469:
1463:
1457:
1456:
1453:
1452:
1444:
1443:
1437:
1434:
1433:
1425:
1424:
1418:
1412:
1411:
1408:
1407:
1399:
1398:
1392:
1389:
1388:
1380:
1379:
1373:
1367:
1366:
1361:
1356:
1352:
1351:
1341:
1340:
1337:
1336:
1325:
1324:
1322:
1321:
1316:
1311:
1306:
1301:
1296:
1291:
1286:
1281:
1276:
1271:
1266:
1261:
1256:
1251:
1246:
1241:
1236:
1231:
1226:
1221:
1216:
1211:
1206:
1201:
1196:
1191:
1186:
1181:
1176:
1171:
1166:
1161:
1156:
1151:
1146:
1141:
1136:
1131:
1126:
1121:
1116:
1111:
1106:
1101:
1096:
1091:
1086:
1081:
1076:
1071:
1066:
1061:
1056:
1051:
1049:cell migration
1046:
1041:
1036:
1031:
1026:
1021:
1016:
1011:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
790:
788:
784:
783:
781:
780:
775:
770:
765:
760:
755:
750:
744:
742:
738:
737:
735:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
683:
681:
677:
676:
666:
665:
662:
661:
658:
657:
649:
648:
623:
617:
616:
613:
612:
604:
603:
600:
599:
597:
596:
592:
588:
584:
580:
576:
572:
568:
564:
560:
556:
553:
552:
541:
538:
537:
535:
534:
530:
526:
522:
518:
514:
510:
506:
502:
498:
494:
491:
490:
478:
477:
469:
458:
452:
451:
448:RNA expression
440:
439:
436:
435:
427:
423:
422:
414:
411:
406:
400:
399:
390:
383:
377:
373:
372:
367:
361:
360:
352:
351:
339:
338:
335:
334:
326:
322:
321:
313:
310:
305:
299:
298:
289:
282:
276:
272:
271:
264:
258:
257:
249:
248:
236:
235:
192:
188:
187:
179:
171:
170:
166:
165:
162:
161:
158:
157:
139:
138:
130:
129:
118:
112:
111:
103:
102:
94:
93:
85:
84:
42:external links
31:
29:
22:
15:
13:
10:
9:
6:
4:
3:
2:
5293:
5282:
5279:
5277:
5274:
5272:
5269:
5268:
5266:
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5240:
5235:
5231:
5225:
5222:
5218:
5214:
5209:
5207:
5205:
5201:
5197:
5193:
5188:
5186:
5184:
5180:
5169:
5166:
5163:
5162:
5158:
5155:
5152:
5149:
5146:
5145:
5142:
5141:Tomoregulin 1
5139:
5137:
5134:
5132:
5129:
5127:
5124:
5122:
5119:
5117:
5116:Gremlin (Drm)
5114:
5112:
5109:
5107:
5104:
5102:
5099:
5097:
5094:
5092:
5089:
5087:
5084:
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5074:
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5021:
5014:
5011:
5009:
5005:
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4992:
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4988:
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4771:
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4703:
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4653:
4650:
4647:
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4644:
4642:
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4609:
4606:
4603:
4600:
4596:
4592:
4588:
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4581:
4579:
4576:
4574:
4571:
4568:
4564:
4560:
4556:
4552:
4548:
4545:
4542:
4541:
4539:
4537:
4531:
4525:
4522:
4520:
4517:
4514:
4513:
4510:
4507:
4505:
4502:
4500:
4497:
4494:
4493:
4489:
4485:
4481:
4477:
4474:
4471:
4467:
4464:
4462:
4459:
4456:
4455:
4453:
4451:
4445:
4442:
4440:
4436:
4426:
4423:
4421:
4418:
4416:
4413:
4410:
4409:
4405:
4401:
4397:
4394:
4391:
4390:
4387:
4384:
4381:
4377:
4373:
4369:
4366:
4363:
4362:
4360:
4358:
4347:
4341:
4338:
4336:
4333:
4331:
4328:
4325:
4324:
4321:
4318:
4315:
4311:
4307:
4303:
4299:
4295:
4292:
4290:
4287:
4285:
4282:
4279:
4275:
4271:
4267:
4263:
4259:
4255:
4251:
4247:
4244:
4241:
4240:
4238:
4236:
4225:
4219:
4216:
4214:
4211:
4209:
4206:
4204:
4201:
4199:
4196:
4194:
4191:
4189:
4186:
4184:
4181:
4179:
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4158:
4157:
4154:
4151:
4149:
4146:
4144:
4141:
4138:
4137:
4133:
4129:
4125:
4121:
4118:
4115:
4111:
4107:
4104:
4102:
4099:
4096:
4095:
4093:
4091:
4080:
4074:
4071:
4069:
4066:
4064:
4061:
4058:
4057:
4053:
4049:
4045:
4042:
4039:
4035:
4031:
4028:
4025:
4024:
4021:
4018:
4016:
4013:
4010:
4006:
4002:
3998:
3995:
3992:
3988:
3984:
3980:
3977:
3974:
3973:
3971:
3969:
3958:
3952:
3949:
3947:
3944:
3942:
3939:
3936:
3935:
3932:
3929:
3927:
3924:
3921:
3917:
3913:
3909:
3905:
3901:
3897:
3893:
3890:
3888:
3885:
3882:
3881:
3879:
3877:
3866:
3860:
3857:
3855:
3852:
3850:
3847:
3845:
3842:
3840:
3837:
3834:
3833:
3829:
3825:
3821:
3817:
3814:
3812:
3809:
3806:
3802:
3798:
3794:
3790:
3786:
3783:
3781:
3778:
3776:
3773:
3770:
3766:
3762:
3758:
3755:
3752:
3751:
3749:
3747:
3736:
3730:
3727:
3724:
3723:
3720:
3717:
3714:
3713:
3710:
3707:
3705:
3702:
3699:
3698:
3695:
3694:Ascrinvacumab
3692:
3689:
3688:
3684:
3680:
3676:
3672:
3669:
3666:
3662:
3659:
3657:
3654:
3651:
3647:
3644:
3642:
3639:
3636:
3632:
3628:
3624:
3621:
3618:
3617:
3615:
3613:
3602:
3599:
3597:
3593:
3589:
3586:
3576:
3571:
3569:
3564:
3562:
3557:
3556:
3553:
3541:
3538:
3536:
3533:
3532:
3530:
3526:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3496:
3494:
3492:
3488:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3463:
3461:
3459:
3455:
3443:
3440:
3438:
3435:
3433:
3430:
3429:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3404:
3402:
3399:
3398:
3392:
3386:
3383:
3381:
3378:
3377:
3375:
3372:
3371:
3367:
3361:
3358:
3356:
3350:
3342:
3339:
3337:
3334:
3332:
3329:
3328:
3327:
3324:
3323:
3321:
3319:
3315:
3309:
3306:
3304:
3301:
3299:
3296:
3295:
3293:
3291:
3287:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3258:
3256:
3253:
3250:
3249:hormone-like:
3245:
3238:
3235:
3232:
3229:
3226:
3223:
3220:
3217:
3216:
3214:
3211:
3206:
3200:
3196:
3192:
3189:
3187:
3183:
3179:
3176:
3174:
3170:
3166:
3163:
3162:
3160:
3157:
3156:
3150:
3144:
3140:
3136:
3133:
3131:
3127:
3123:
3120:
3119:
3117:
3114:
3112:
3106:
3103:
3101:
3097:
3093:
3086:
3081:
3079:
3074:
3072:
3067:
3066:
3063:
3051:
3048:
3047:
3045:
3041:
3035:
3032:
3030:
3027:
3026:
3024:
3022:
3018:
3012:
3009:
3007:
3004:
3002:
2999:
2997:
2994:
2992:
2989:
2987:
2984:
2982:
2979:
2977:
2974:
2972:
2969:
2967:
2964:
2963:
2961:
2959:
2955:
2949:
2946:
2943:
2940:
2938:
2934:
2931:
2928:
2925:
2923:
2920:
2918:
2915:
2913:
2910:
2908:
2904:
2901:
2900:
2898:
2896:
2892:
2888:
2878:
2875:
2874:
2872:
2868:
2862:
2859:
2857:
2854:
2850:
2847:
2845:
2842:
2841:
2840:
2837:
2836:
2834:
2830:
2822:
2819:
2817:
2814:
2813:
2812:
2809:
2807:
2804:
2800:
2797:
2795:
2792:
2790:
2787:
2786:
2785:
2782:
2781:
2779:
2775:
2772:
2769:
2765:
2761:
2756:
2752:
2742:
2739:
2735:
2732:
2730:
2727:
2725:
2722:
2720:
2717:
2715:
2712:
2710:
2707:
2705:
2702:
2700:
2697:
2695:
2692:
2690:
2687:
2685:
2682:
2681:
2680:
2677:
2673:
2670:
2668:
2665:
2663:
2660:
2658:
2655:
2653:
2650:
2648:
2645:
2643:
2640:
2638:
2635:
2633:
2630:
2628:
2625:
2624:
2623:
2620:
2619:
2617:
2615:
2610:
2604:
2601:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2578:
2577:
2574:
2570:
2567:
2565:
2562:
2560:
2557:
2556:
2555:
2552:
2551:
2549:
2547:
2543:
2538:
2535:
2533:
2529:
2525:
2521:
2514:
2509:
2507:
2502:
2500:
2495:
2494:
2491:
2477:
2471:
2466:
2462:
2456:
2451:
2447:
2438:
2433:
2431:
2426:
2424:
2419:
2418:
2415:
2406:
2402:
2398:
2394:
2390:
2386:
2382:
2378:
2373:
2369:
2365:
2361:
2357:
2353:
2349:
2346:(4): 411–26.
2345:
2341:
2336:
2332:
2328:
2323:
2318:
2314:
2310:
2307:(4): 557–68.
2306:
2302:
2298:
2293:
2289:
2285:
2280:
2275:
2271:
2267:
2263:
2259:
2254:
2250:
2246:
2241:
2236:
2232:
2228:
2227:J. Biol. Chem
2224:
2219:
2215:
2211:
2206:
2201:
2198:(2): 687–93.
2197:
2193:
2189:
2184:
2180:
2176:
2171:
2166:
2162:
2158:
2157:J. Biol. Chem
2154:
2149:
2145:
2141:
2136:
2131:
2127:
2123:
2119:
2115:
2111:
2106:
2102:
2098:
2095:(4): 323–31.
2094:
2090:
2085:
2081:
2077:
2073:
2069:
2065:
2061:
2056:
2052:
2048:
2044:
2040:
2036:
2032:
2027:
2023:
2019:
2015:
2011:
2007:
2003:
1998:
1994:
1990:
1986:
1982:
1979:(4): 247–55.
1978:
1974:
1969:
1965:
1961:
1957:
1953:
1949:
1945:
1941:
1937:
1933:
1929:
1924:
1920:
1916:
1912:
1908:
1904:
1900:
1896:
1892:
1888:
1883:
1879:
1875:
1870:
1865:
1861:
1857:
1853:
1849:
1845:
1840:
1836:
1832:
1827:
1822:
1819:(4): 179–90.
1818:
1814:
1813:
1808:
1803:
1799:
1795:
1791:
1787:
1783:
1779:
1776:(2): 177–85.
1775:
1771:
1770:J. Neurooncol
1766:
1762:
1758:
1754:
1750:
1746:
1742:
1737:
1736:
1731:
1729:
1727:
1726:
1721:
1717:
1713:
1710:
1706:
1702:
1699:
1698:extracellular
1695:
1693:
1688:
1684:
1680:
1668:
1663:
1659:
1655:
1652:
1648:
1641:
1639:
1636:
1632:
1628:
1624:
1621:
1617:
1613:
1606:
1604:
1600:
1594:
1590:
1587:
1581:
1579:
1575:
1569:
1565:
1562:
1558:
1551:
1549:
1545:
1539:
1535:
1532:
1526:
1524:
1520:
1514:
1510:
1507:
1505:RefSeq (mRNA)
1503:
1496:
1495:
1490:
1486:
1483:
1477:
1476:
1471:
1467:
1464:
1462:
1458:
1451:
1450:
1445:
1441:
1438:
1432:
1431:
1426:
1422:
1419:
1417:
1413:
1406:
1405:
1400:
1396:
1393:
1387:
1386:
1381:
1377:
1374:
1372:
1368:
1365:
1362:
1360:
1357:
1353:
1350:
1346:
1342:
1335:
1331:
1326:
1320:
1317:
1315:
1312:
1310:
1307:
1305:
1302:
1300:
1297:
1295:
1292:
1290:
1287:
1285:
1282:
1280:
1277:
1275:
1272:
1270:
1267:
1265:
1262:
1260:
1257:
1255:
1252:
1250:
1247:
1245:
1242:
1240:
1237:
1235:
1232:
1230:
1227:
1225:
1222:
1220:
1217:
1215:
1212:
1210:
1207:
1205:
1202:
1200:
1197:
1195:
1192:
1190:
1187:
1185:
1182:
1180:
1177:
1175:
1172:
1170:
1167:
1165:
1162:
1160:
1157:
1155:
1152:
1150:
1147:
1145:
1142:
1140:
1137:
1135:
1132:
1130:
1127:
1125:
1122:
1120:
1117:
1115:
1112:
1110:
1107:
1105:
1102:
1100:
1097:
1095:
1092:
1090:
1087:
1085:
1082:
1080:
1077:
1075:
1072:
1070:
1067:
1065:
1062:
1060:
1057:
1055:
1052:
1050:
1047:
1045:
1042:
1040:
1037:
1035:
1032:
1030:
1027:
1025:
1022:
1020:
1017:
1015:
1012:
1010:
1007:
1005:
1002:
1000:
997:
995:
992:
990:
987:
985:
982:
980:
977:
975:
972:
970:
967:
965:
962:
960:
959:odontogenesis
957:
955:
952:
950:
947:
945:
942:
940:
939:wound healing
937:
935:
932:
930:
927:
925:
922:
920:
917:
915:
912:
910:
907:
905:
902:
900:
897:
895:
892:
890:
887:
885:
882:
880:
877:
875:
872:
870:
867:
865:
862:
860:
857:
855:
852:
850:
847:
845:
842:
840:
837:
835:
832:
830:
827:
825:
822:
820:
817:
815:
812:
810:
807:
805:
802:
800:
797:
795:
792:
791:
789:
786:
785:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
754:
751:
749:
746:
745:
743:
740:
739:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
684:
682:
679:
678:
675:
674:Gene ontology
671:
667:
655:
650:
646:
639:
632:
627:
624:
622:
618:
610:
605:
594:
590:
586:
582:
578:
574:
570:
566:
562:
558:
557:
554:
550:
545:
542:
532:
528:
524:
520:
516:
512:
508:
504:
500:
496:
495:
492:
488:
483:
480:
479:
476:
474:
470:
468:
467:
463:
462:
459:
457:
453:
449:
445:
441:
433:
428:
424:
420:
415:
405:
401:
394:
387:
381:
374:
366:
362:
358:
353:
349:
344:
340:
332:
327:
323:
319:
314:
304:
300:
293:
286:
280:
273:
269:
263:
259:
255:
250:
246:
241:
237:
233:
229:
225:
221:
217:
213:
209:
205:
201:
197:
189:
184:
177:
172:
167:
156:
154:
150:
146:
140:
135:
132:
131:
127:
124:
117:
113:
108:
104:
100:
95:
90:
81:
78:
70:
60:
56:
50:
49:
43:
39:
35:
30:
21:
20:
5251:
5242:
5233:
5224:
5164:
5147:
5082:
5057:
5027:
4990:
4962:
4930:Antagonists:
4929:
4828:
4805:
4773:Antagonists:
4772:
4648:
4612:Antagonists:
4611:
4543:
4515:
4504:Lerdelimumab
4499:Fresolimumab
4495:
4483:
4457:
4411:
4393:Antagonists:
4392:
4364:
4326:
4242:
4159:
4148:Lerdelimumab
4143:Fresolimumab
4139:
4127:
4097:
4059:
4027:Antagonists:
4026:
3975:
3937:
3883:
3835:
3823:
3753:
3725:
3719:Dalantercept
3715:
3700:
3690:
3678:
3619:
3395:
3364:
3353:Insulin/IGF/
3335:
3318:TGFβ pathway
3248:
3209:
3153:
3111:FGF receptor
3109:
2563:
2475:
2460:
2383:(1): 153–9.
2380:
2376:
2343:
2339:
2304:
2301:J. Cell Biol
2300:
2261:
2230:
2226:
2195:
2191:
2160:
2156:
2117:
2113:
2092:
2089:Oncogene Res
2088:
2063:
2059:
2037:(7): 493–7.
2034:
2030:
2008:(2): 890–7.
2005:
2001:
1976:
1972:
1931:
1927:
1894:
1890:
1851:
1847:
1816:
1810:
1773:
1769:
1747:(3): 293–8.
1744:
1740:
1723:
1718:of the same
1701:glycosylated
1696:). It is an
1692:Glioblastoma
1690:
1678:
1677:
1599:NP_001316036
1596:
1574:NP_001129071
1571:
1548:NM_001329107
1541:
1523:NM_001135599
1516:
1492:
1473:
1447:
1428:
1402:
1383:
1363:
1358:
839:angiogenesis
567:ciliary body
471:
464:
430:186,438,186
417:186,354,989
329:218,444,619
316:218,345,336
191:External IDs
142:
73:
64:
53:Please help
45:
5281:TGFβ domain
5148:Antibodies:
5111:Follistatin
4966:Ramatercept
4809:Sotatercept
4509:Metelimumab
4496:Antibodies:
4153:Metelimumab
4140:Antibodies:
3729:Disitertide
3691:Antibodies:
3021:Coreceptors
2981:Follistatin
2891:Transducers
2443:PDB gallery
1705:interleukin
1164:hemopoiesis
169:Identifiers
59:introducing
5265:Categories
5219:, May 2017
5198:, May 2017
5151:Stamulumab
5101:DAN (PARN)
5020:(β-glycan)
4923:Radotermin
4766:Radotermin
4746:11 (BMP11)
4702:15 (GDF9B)
4605:Radotermin
4470:10 (BMP3B)
4380:11 (BMP11)
4320:Radotermin
4278:15 (GDF9B)
4183:LY-2109761
4114:11 (BMP11)
4110:10 (BMP3B)
4009:11 (BMP11)
3588:modulators
3540:Hepatocyte
3100:Fibroblast
2877:betaglycan
2612:Ligand of
2540:Ligand of
2262:Biochem. J
2066:(1): 1–8.
1707:dependent
809:cell death
475:(ortholog)
212:HomoloGene
67:March 2019
5031:Avotermin
4994:AMH (MIS)
4991:Agonists:
4902:7 (BMP12)
4898:6 (BMP13)
4894:5 (BMP14)
4829:Agonists:
4738:7 (BMP12)
4734:6 (BMP13)
4730:5 (BMP14)
4649:Agonists:
4599:7 (BMP12)
4595:6 (BMP13)
4591:5 (BMP14)
4544:Agonists:
4524:LY-364947
4461:Avotermin
4458:Agonists:
4425:SB-505124
4420:SB-431542
4365:Agonists:
4306:7 (BMP12)
4302:6 (BMP13)
4298:5 (BMP14)
4243:Agonists:
4213:SB-525334
4208:SB-505124
4203:SB-431542
4178:LY-364947
4173:GW-788388
4101:Avotermin
4098:Agonists:
4073:SB-505124
4068:SB-431542
3976:Agonists:
3887:AMH (MIS)
3884:Agonists:
3780:Avotermin
3775:AMH (MIS)
3754:Agonists:
3641:Avotermin
3620:Agonists:
1603:NP_033393
1578:NP_003229
1544:NM_009367
1519:NM_003238
1349:Orthologs
220:GeneCards
5276:Proteins
5215:–
5194:–
5168:Endoglin
5076:Unsorted
5028:Ligands:
5008:Type III
4587:2 (BMP9)
4193:R-268712
3665:2 (BMP9)
3656:Cetermin
3252:FGF15/19
3113:ligands:
2966:Cerberus
2405:21284888
2397:10457363
2368:85850306
1878:14679171
1835:11795478
1798:21461718
1790:11716069
1683:cytokine
1651:Wikidata
1328:Sources:
5217:Ensembl
5196:Ensembl
5165:Others:
5106:Decorin
5096:Chordin
5036:Inhibin
4933:Inhibin
4832:Activin
4776:Inhibin
4652:Activin
4615:Inhibin
4439:Type II
4415:A 83-01
4340:K-02288
4163:A 83-01
4063:A 83-01
4030:Inhibin
3979:Activin
3951:K-02288
3854:K-02288
3757:Activin
3704:K-02288
3623:Activin
3427:Relaxin
3366:Insulin
2986:Gremlin
2976:Decorin
2971:Chordin
2870:TGFBR3:
2832:TGFBR2:
2777:TGFBR1:
2760:Activin
2360:9493905
2331:8106553
2322:2119924
2288:8093006
2279:1137259
2249:7852346
2214:7513640
2179:3476488
2144:3322813
2101:3226728
2080:3162414
2051:2850146
2022:2119582
1993:1764261
1964:4239431
1956:1641027
1936:Bibcode
1919:1631557
1899:Bibcode
1891:Science
1761:9611771
1722:(i.e.,
1461:UniProt
1416:Ensembl
1355:Species
1334:QuickGO
563:decidua
450:pattern
176:Aliases
55:improve
5157:TRC105
5126:Noggin
5018:TGFβR3
4820:ACVR2B
4635:ACVR2A
4449:TGFβR2
4355:ACVR1C
4233:BMPR1B
4218:SD-208
4168:D-4476
4088:TGFβR1
3966:ACVR1B
3874:BMPR1A
3744:ACVR1A
3610:ACVRL1
3596:Type I
3514:VEGF-D
3509:VEGF-C
3504:VEGF-B
3499:VEGF-A
3308:HB-EGF
3239:(FHF4)
3233:(FHF2)
3227:(FHF1)
3221:(FHF3)
3034:Cripto
3001:Noggin
2933:I-SMAD
2903:R-SMAD
2849:ACVR2B
2844:ACVR2A
2821:BMPR1B
2816:BMPR1A
2806:ACVRL1
2799:ACVR1C
2794:ACVR1B
2768:family
2569:TGF-β3
2564:TGF-β2
2559:TGF-β1
2403:
2395:
2366:
2358:
2329:
2319:
2286:
2276:
2247:
2212:
2177:
2142:
2135:553836
2132:
2114:EMBO J
2099:
2078:
2049:
2020:
1991:
1962:
1954:
1928:Nature
1917:
1876:
1869:297008
1866:
1833:
1796:
1788:
1759:
1712:tumors
1709:T-cell
1637:search
1635:PubMed
1494:P27090
1475:P61812
1371:Entrez
621:BioGPS
200:190220
5121:LTBP1
5086:BAMBI
4977:AMHR2
4947:Lefty
4913:Nodal
4790:Lefty
4761:Nodal
4639:ACVR2
4535:BMPR2
4519:DMH-2
4396:Lefty
4386:Nodal
4330:DMH-2
4044:Lefty
4020:Nodal
3941:DMH-2
3844:DMH-2
3839:DMH-1
3535:Nerve
3528:Other
3481:PDGFD
3476:PDGFC
3471:PDGFB
3466:PDGFA
3422:INSL6
3417:INSL5
3412:INSL4
3407:INSL3
3341:TGFβ3
3336:TGFβ2
3331:TGFβ1
3276:FGF23
3271:FGF21
3266:FGF19
3261:FGF15
3237:FGF14
3231:FGF13
3225:FGF12
3219:FGF11
3199:FGF20
3195:FGF16
3186:FGF18
3182:FGF17
3173:FGF22
3169:FGF10
3043:Other
3029:BAMBI
3011:THBS1
2996:LTBP1
2991:Lefty
2948:SMAD4
2942:SMAD7
2937:SMAD6
2927:SMAD9
2922:SMAD5
2917:SMAD3
2912:SMAD2
2907:SMAD1
2861:BMPR2
2856:AMHR2
2811:BMPR1
2789:ACVR1
2734:GDF15
2729:GDF11
2724:GDF10
2672:BMP15
2667:BMP10
2662:BMP8b
2657:BMP8a
2603:Nodal
2596:INHBC
2591:INHBB
2586:INHBA
2546:TGFBR
2401:S2CID
2364:S2CID
1960:S2CID
1794:S2CID
1725:TGFB2
1404:21808
1364:Mouse
1359:Human
1330:Amigo
525:tibia
513:sperm
473:Mouse
466:Human
413:Start
348:Mouse
312:Start
245:Human
224:TGFB2
208:98726
183:TGFB2
92:TGFB2
40:, or
5131:TGIF
5050:TGFβ
4981:AMHR
4476:TGFβ
4351:ALK7
4229:ALK6
4120:TGFβ
4084:ALK5
3962:ALK4
3870:ALK3
3816:TGFβ
3740:ALK2
3671:TGFβ
3606:ALK1
3583:TGFβ
3385:IGF2
3380:IGF1
3368:and
3326:TGFβ
3298:TGFα
3191:FGF9
3178:FGF8
3165:FGF7
3143:FGF6
3139:FGF4
3135:FGF3
3130:FGF5
3126:FGF2
3122:FGF1
3050:SARA
3006:PARN
2895:SMAD
2719:GDF9
2709:GDF7
2704:GDF6
2699:GDF5
2694:GDF3
2689:GDF2
2684:GDF1
2652:BMP7
2647:BMP6
2642:BMP5
2637:BMP4
2632:BMP3
2627:BMP2
2614:BMPR
2581:INHA
2542:ACVR
2476:2tgi
2461:1tfg
2393:PMID
2356:PMID
2327:PMID
2284:PMID
2245:PMID
2210:PMID
2175:PMID
2140:PMID
2097:PMID
2076:PMID
2047:PMID
2018:PMID
1989:PMID
1952:PMID
1915:PMID
1874:PMID
1831:PMID
1786:PMID
1757:PMID
1720:gene
1385:7042
768:axon
571:iris
456:Bgee
404:Band
365:Chr.
308:1q41
303:Band
262:Chr.
216:2432
196:OMIM
153:4KXZ
149:2TGI
145:1TFG
126:RCSB
123:PDBe
4882:GDF
4850:BMP
4718:GDF
4670:BMP
4583:GDF
4547:BMP
4466:GDF
4368:GDF
4294:GDF
4246:BMP
4106:GDF
3997:GDF
3892:BMP
3785:BMP
3661:GDF
3646:BMP
3519:PGF
3303:EGF
3155:KGF
2764:BMP
2544:or
2385:doi
2381:181
2348:doi
2317:PMC
2309:doi
2305:124
2274:PMC
2266:doi
2235:doi
2231:270
2200:doi
2196:221
2165:doi
2161:262
2130:PMC
2122:doi
2068:doi
2060:DNA
2039:doi
2031:DNA
2010:doi
2006:171
1981:doi
1944:doi
1932:358
1907:doi
1895:257
1864:PMC
1856:doi
1852:112
1821:doi
1778:doi
1749:doi
1728:).
426:End
325:End
228:OMA
204:MGI
116:PDB
5267::
5250:.
5232:.
5203:^
5182:^
5060:,
5056:,
5042:,
4953:,
4939:,
4900:,
4896:,
4892:,
4888:,
4864:,
4860:,
4856:,
4844:AB
4842:,
4838:,
4796:,
4782:,
4750:15
4748:,
4744:,
4740:,
4736:,
4732:,
4728:,
4724:,
4700:,
4698:8B
4696:,
4694:8A
4692:,
4688:,
4684:,
4680:,
4676:,
4664:AB
4662:,
4658:,
4621:,
4597:,
4593:,
4589:,
4567:10
4565:,
4561:,
4557:,
4553:,
4486:,
4482:,
4402:,
4378:,
4374:,
4314:15
4312:,
4308:,
4304:,
4300:,
4276:,
4274:8B
4272:,
4270:8A
4268:,
4264:,
4260:,
4256:,
4252:,
4130:,
4126:,
4112:,
4050:,
4036:,
4007:,
4003:,
3991:AB
3989:,
3985:,
3920:8B
3918:,
3916:8A
3914:,
3910:,
3906:,
3902:,
3898:,
3826:,
3822:,
3805:8B
3803:,
3801:8A
3799:,
3795:,
3791:,
3769:AB
3767:,
3763:,
3681:,
3677:,
3650:10
3635:AB
3633:,
3629:,
2766:,
2762:,
2522::
2399:.
2391:.
2379:.
2362:.
2354:.
2344:68
2342:.
2325:.
2315:.
2303:.
2299:.
2282:.
2272:.
2260:.
2243:.
2229:.
2225:.
2208:.
2194:.
2190:.
2173:.
2159:.
2155:.
2138:.
2128:.
2116:.
2112:.
2091:.
2074:.
2062:.
2045:.
2033:.
2016:.
2004:.
1987:.
1975:.
1958:.
1950:.
1942:.
1930:.
1913:.
1905:.
1893:.
1889:.
1872:.
1862:.
1850:.
1846:.
1829:.
1817:33
1815:.
1809:.
1792:.
1784:.
1774:53
1772:.
1755:.
1745:30
1743:.
1332:/
432:bp
419:bp
331:bp
318:bp
226:;
222::
218:;
214::
210:;
206::
202:;
198::
151:,
147:,
44:,
36:,
5254:.
5236:.
5064:)
5062:3
5058:2
5054:1
5052:(
5046:)
5044:B
5040:A
5038:(
4983:)
4979:(
4957:)
4955:2
4951:1
4949:(
4943:)
4941:B
4937:A
4935:(
4904:)
4890:3
4886:1
4884:(
4868:)
4866:7
4862:6
4858:4
4854:2
4852:(
4846:)
4840:B
4836:A
4834:(
4800:)
4798:2
4794:1
4792:(
4786:)
4784:B
4780:A
4778:(
4752:)
4742:9
4726:3
4722:1
4720:(
4704:)
4690:7
4686:6
4682:5
4678:4
4674:2
4672:(
4666:)
4660:B
4656:A
4654:(
4641:)
4637:(
4625:)
4623:B
4619:A
4617:(
4601:)
4585:(
4569:)
4563:7
4559:6
4555:4
4551:2
4549:(
4490:)
4488:3
4484:2
4480:1
4478:(
4472:)
4468:(
4406:)
4404:2
4400:1
4398:(
4382:)
4376:3
4372:1
4370:(
4357:)
4353:(
4316:)
4310:9
4296:(
4280:)
4266:7
4262:6
4258:5
4254:4
4250:2
4248:(
4235:)
4231:(
4134:)
4132:3
4128:2
4124:1
4122:(
4116:)
4108:(
4090:)
4086:(
4054:)
4052:2
4048:1
4046:(
4040:)
4038:B
4034:A
4032:(
4011:)
4005:3
4001:1
3999:(
3993:)
3987:B
3983:A
3981:(
3968:)
3964:(
3922:)
3912:7
3908:6
3904:5
3900:4
3896:2
3894:(
3876:)
3872:(
3830:)
3828:3
3824:2
3820:1
3818:(
3807:)
3797:7
3793:6
3789:5
3787:(
3771:)
3765:B
3761:A
3759:(
3746:)
3742:(
3685:)
3683:3
3679:2
3675:1
3673:(
3667:)
3663:(
3652:)
3648:(
3637:)
3631:B
3627:A
3625:(
3612:)
3608:(
3574:e
3567:t
3560:v
3442:3
3437:2
3432:1
3197:/
3193:/
3184:/
3180:/
3171:/
3167:/
3141:/
3137:/
3128:/
3124:/
3084:e
3077:t
3070:v
2944:)
2935:(
2929:)
2905:(
2893:/
2770:)
2758:(
2512:e
2505:t
2498:v
2436:e
2429:t
2422:v
2407:.
2387::
2370:.
2350::
2333:.
2311::
2290:.
2268::
2251:.
2237::
2216:.
2202::
2181:.
2167::
2146:.
2124::
2118:6
2103:.
2093:3
2082:.
2070::
2064:7
2053:.
2041::
2035:7
2024:.
2012::
1995:.
1983::
1977:4
1966:.
1946::
1938::
1921:.
1909::
1901::
1880:.
1858::
1837:.
1823::
1800:.
1780::
1763:.
1751::
350:)
247:)
230::
80:)
74:(
69:)
65:(
51:.
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